-
1
-
-
84946409554
-
Time course of cardiometabolic alterations in a high fat high sucrose diet mice model and improvement after GLP-1 analog treatment using multimodal cardiovascular magnetic resonance
-
Abdesselam, I., Pepino, P., Troalen, T., Macia, M., Ancel, P., Masi, B., et al. (2015). Time course of cardiometabolic alterations in a high fat high sucrose diet mice model and improvement after GLP-1 analog treatment using multimodal cardiovascular magnetic resonance. J. Cardiovasc. Magn. Reson. 17:95. doi: 10.1186/s12968-015-0198-x
-
(2015)
J. Cardiovasc. Magn. Reson.
, vol.17
, pp. 95
-
-
Abdesselam, I.1
Pepino, P.2
Troalen, T.3
Macia, M.4
Ancel, P.5
Masi, B.6
-
2
-
-
84910067714
-
Cardiac diastolic dysfunction in high-fat diet fed mice is associated with lipotoxicity without impairment of cardiac energetics in vivo
-
Abdurrachim, D., Ciapaite, J., Wessels, B., Nabben, M., Luiken, J. J., Nicolay, K., et al. (2014). Cardiac diastolic dysfunction in high-fat diet fed mice is associated with lipotoxicity without impairment of cardiac energetics in vivo. Biochim. Biophys. Acta Mol. Cell Biol. Lipids 1841, 1525-1537. doi: 10.1016/j.bbalip.2014.07.016
-
(2014)
Biochim. Biophys. Acta Mol. Cell Biol. Lipids
, vol.1841
, pp. 1525-1537
-
-
Abdurrachim, D.1
Ciapaite, J.2
Wessels, B.3
Nabben, M.4
Luiken, J.J.5
Nicolay, K.6
-
3
-
-
85031718578
-
Diabetic db/db mice do not develop heart failure upon pressure overload: A longitudinal in vivo PET, MRI, and MRS study on cardiac metabolic, structural, and functional adaptations
-
Abdurrachim, D., Nabben, M., Hoerr, V., Kuhlmann, M. T., Bovenkamp, P., Ciapaite, J., et al. (2017). Diabetic db/db mice do not develop heart failure upon pressure overload: a longitudinal in vivo PET, MRI, and MRS study on cardiac metabolic, structural, and functional adaptations. Cardiovasc. Res. 113, 1148-1160. doi: 10.1093/cvr/cvx100
-
(2017)
Cardiovasc. Res.
, vol.113
, pp. 1148-1160
-
-
Abdurrachim, D.1
Nabben, M.2
Hoerr, V.3
Kuhlmann, M.T.4
Bovenkamp, P.5
Ciapaite, J.6
-
4
-
-
84936889159
-
Current state and future challenges of mass spectrometry imaging for clinical research
-
Addie, R. D., Balluff, B., Bovée, J. V., Morreau, H., and McDonnell, L. A. (2015). Current state and future challenges of mass spectrometry imaging for clinical research. Anal. Chem. 87, 6426-6433. doi: 10.1021/acs.analchem.5b00416
-
(2015)
Anal. Chem.
, vol.87
, pp. 6426-6433
-
-
Addie, R.D.1
Balluff, B.2
Bovée, J.V.3
Morreau, H.4
McDonnell, L.A.5
-
5
-
-
84959431623
-
A diet rich in medium-chain fatty acids improves systolic function and alters the lipidomic profile in patients with type 2 diabetes: A pilot study
-
Airhart, S., Cade, W. T., Jiang, H., Coggan, A. R., Racette, S. B., Korenblat, K., et al. (2016). A diet rich in medium-chain fatty acids improves systolic function and alters the lipidomic profile in patients with type 2 diabetes: a pilot study. J. Clin. Endocrinol. Metab. 101, 504-512. doi: 10.1210/jc.2015-3292
-
(2016)
J. Clin. Endocrinol. Metab.
, vol.101
, pp. 504-512
-
-
Airhart, S.1
Cade, W.T.2
Jiang, H.3
Coggan, A.R.4
Racette, S.B.5
Korenblat, K.6
-
6
-
-
84921732687
-
Dietary nitrate increases arginine availability and protects mitochondrial complex I and energetics in the hypoxic rat heart
-
Ashmore, T., Fernandez, B. O., Branco-Price, C., West, J. A., Cowburn, A. S., Heather, L. C., et al. (2014). Dietary nitrate increases arginine availability and protects mitochondrial complex I and energetics in the hypoxic rat heart. J. Physiol. 592, 4715-4731. doi: 10.1113/jphysiol.2014.275263
-
(2014)
J. Physiol.
, vol.592
, pp. 4715-4731
-
-
Ashmore, T.1
Fernandez, B.O.2
Branco-Price, C.3
West, J.A.4
Cowburn, A.S.5
Heather, L.C.6
-
7
-
-
79951820751
-
Validation of the in vivo assessment of pyruvate dehydrogenase activity using hyperpolarised 13C MRS
-
Atherton, H. J., Schroeder, M. A., Dodd, M. S., Heather, L. C., Carter, E. E., Cochlin, L. E., et al. (2011). Validation of the in vivo assessment of pyruvate dehydrogenase activity using hyperpolarised 13C MRS. NMR Biomed. 24, 201-208. doi: 10.1002/nbm.1573
-
(2011)
NMR Biomed
, vol.24
, pp. 201-208
-
-
Atherton, H.J.1
Schroeder, M.A.2
Dodd, M.S.3
Heather, L.C.4
Carter, E.E.5
Cochlin, L.E.6
-
8
-
-
84975775560
-
The failing heart relies on ketone bodies as a fuel
-
Aubert, G., Martin, O. J., Horton, J. L., Lai, L., Vega, R. B., Leone, T. C., et al. (2016). The failing heart relies on ketone bodies as a fuel. Circulation 133, 698-705. doi: 10.1161/CIRCULATIONAHA.115.017355
-
(2016)
Circulation
, vol.133
, pp. 698-705
-
-
Aubert, G.1
Martin, O.J.2
Horton, J.L.3
Lai, L.4
Vega, R.B.5
Leone, T.C.6
-
9
-
-
0025266282
-
Myocardial metabolism in insulin-deficient diabetic humans without coronary artery disease
-
Avogaro, A., Nosadini, R., Doria, A., Fioretto, P., Velussi, M., Vigorito, C., et al. (1990). Myocardial metabolism in insulin-deficient diabetic humans without coronary artery disease. Am. J. Physiol. Endocrinol. Metab. 258, E606-E618. doi: 10.1152/ajpendo.1990.258.4.E606
-
(1990)
Am. J. Physiol. Endocrinol. Metab.
, vol.258
, pp. E606-E618
-
-
Avogaro, A.1
Nosadini, R.2
Doria, A.3
Fioretto, P.4
Velussi, M.5
Vigorito, C.6
-
10
-
-
73149086391
-
Myocardium of type 2 diabetic and obese patients is characterized by alterations in sphingolipid metabolic enzymes but not by accumulation of ceramide
-
Baranowski, M., Blachnio-Zabielska, A., Hirnle, T., Harasiuk, D., Matlak, K., Knapp, M., et al. (2010). Myocardium of type 2 diabetic and obese patients is characterized by alterations in sphingolipid metabolic enzymes but not by accumulation of ceramide. J. Lipid Res. 51, 74-80. doi: 10.1194/jlr.M900002-JLR200
-
(2010)
J. Lipid Res.
, vol.51
, pp. 74-80
-
-
Baranowski, M.1
Blachnio-Zabielska, A.2
Hirnle, T.3
Harasiuk, D.4
Matlak, K.5
Knapp, M.6
-
11
-
-
72249100585
-
Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function
-
Basu, R., Oudit, G. Y., Wang, X., Zhang, L., Ussher, J. R., Lopaschuk, G. D., et al. (2009). Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function. Am. J. Physiol. Heart Circ. Physiol. 297, H2096-H2108. doi: 10.1152/ajpheart.00452.2009
-
(2009)
Am. J. Physiol. Heart Circ. Physiol.
, vol.297
, pp. H2096-H2108
-
-
Basu, R.1
Oudit, G.Y.2
Wang, X.3
Zhang, L.4
Ussher, J.R.5
Lopaschuk, G.D.6
-
12
-
-
84975775436
-
Evidence for intramyocardial disruption of lipid metabolism and increased myocardial ketone utilization in advanced human heart failure
-
Bedi, K. C. Jr., Snyder, N. W., Brandimarto, J., Aziz, M., Mesaros, C., Worth, A. J., et al. (2016). Evidence for intramyocardial disruption of lipid metabolism and increased myocardial ketone utilization in advanced human heart failure. Circulation 133, 706-716. doi: 10.1161/CIRCULATIONAHA.115.017545
-
(2016)
Circulation
, vol.133
, pp. 706-716
-
-
Bedi, K.C.1
Snyder, N.W.2
Brandimarto, J.3
Aziz, M.4
Mesaros, C.5
Worth, A.J.6
-
13
-
-
0141669148
-
Diabetic cardiomyopathy
-
Bell, D. S. H. (2003). Diabetic cardiomyopathy. Diabetes Care 26, 2949-2951. doi: 10.2337/diacare.26.10.2949
-
(2003)
Diabetes Care
, vol.26
, pp. 2949-2951
-
-
Bell, D.S.H.1
-
14
-
-
79957829995
-
Exercise-induced modulation of cardiac lipid content in healthy lean young men
-
Bilet, L., van de Weijer, T., Hesselink, M. K., Glatz, J. F., Lamb, H. J., Wildberger, J., et al. (2011). Exercise-induced modulation of cardiac lipid content in healthy lean young men. Basic Res. Cardiol. 106, 307-315. doi: 10.1007/s00395-010-0144-x
-
(2011)
Basic Res. Cardiol.
, vol.106
, pp. 307-315
-
-
Bilet, L.1
Van De Weijer, T.2
Hesselink, M.K.3
Glatz, J.F.4
Lamb, H.J.5
Wildberger, J.6
-
15
-
-
50449119332
-
Metabolism of the human heart: II. Studies on fat, ketone and amino acid metabolism
-
Bing, R. J., Siegel, A., Ungar, I., and Gilbert, M. (1954). Metabolism of the human heart: II. Studies on fat, ketone and amino acid metabolism. Am. J. Med. 16, 504-515. doi: 10.1016/0002-9343(54)90365-4
-
(1954)
Am. J. Med.
, vol.16
, pp. 504-515
-
-
Bing, R.J.1
Siegel, A.2
Ungar, I.3
Gilbert, M.4
-
16
-
-
85042096322
-
Diabetes and branched-chain amino acids: What is the link?
-
Bloomgarden, Z. (2018). Diabetes and branched-chain amino acids: what is the link? J. Diabetes 10, 350-352. doi: 10.1111/1753-0407.12645
-
(2018)
J. Diabetes
, vol.10
, pp. 350-352
-
-
Bloomgarden, Z.1
-
17
-
-
85033215915
-
Exercise of obese mice induces cardioprotection and oxygen sparing in hearts exposed to high-fat load
-
Boardman, N. T., Hafstad, A. D., Lund, J., Rossvoll, L., and Aasum, E. (2017). Exercise of obese mice induces cardioprotection and oxygen sparing in hearts exposed to high-fat load. Am. J. Physiol. Heart Circ. Physiol. 313, H1054-H1062. doi: 10.1152/ajpheart.00382.2017
-
(2017)
Am. J. Physiol. Heart Circ. Physiol.
, vol.313
, pp. H1054-H1062
-
-
Boardman, N.T.1
Hafstad, A.D.2
Lund, J.3
Rossvoll, L.4
Aasum, E.5
-
18
-
-
33751255379
-
Cardiac remodeling rather than disturbed myocardial energy metabolism is associated with cardiac dysfunction in diabetic rats
-
Bollano, E., Omerovic, E., Svensson, H., Waagstein, F., and Fu, M. (2007). Cardiac remodeling rather than disturbed myocardial energy metabolism is associated with cardiac dysfunction in diabetic rats. Int. J. Cardiol. 114, 195-201. doi: 10.1016/j.ijcard.2006.01.027
-
(2007)
Int. J. Cardiol.
, vol.114
, pp. 195-201
-
-
Bollano, E.1
Omerovic, E.2
Svensson, H.3
Waagstein, F.4
Fu, M.5
-
19
-
-
84930874656
-
Heart failure: An overview
-
A. Fishman New York, NY: McGraw Hill
-
Braunwald, E. (1978). “Heart failure: an overview,” in Heart Failure, ed. A. P. Fishman (New York, NY: McGraw Hill), 55-70.
-
(1978)
Heart Failure
, pp. 55-70
-
-
Braunwald, E.1
-
20
-
-
84869081812
-
Trimetazidine reduces endogenous free fatty acid oxidation and improves myocardial efficiency in obese humans
-
Bucci, M., Borra, R., Någren, K., Pärkkä, J. P., Ry, S. D., Maggio, R., et al. (2012). Trimetazidine reduces endogenous free fatty acid oxidation and improves myocardial efficiency in obese humans. Cardiovasc. Ther. 30, 333-341. doi: 10.1111/j.1755-5922.2011.00275.x
-
(2012)
Cardiovasc. Ther.
, vol.30
, pp. 333-341
-
-
Bucci, M.1
Borra, R.2
Någren, K.3
Pärkkä, J.P.4
Ry, S.D.5
Maggio, R.6
-
21
-
-
34248393099
-
High-fat diets: Modeling the metabolic disorders of human obesity in rodents
-
Buettner, R., Schölmerich, J., and Bollheimer, L. C. (2007). High-fat diets: modeling the metabolic disorders of human obesity in rodents. Obesity 15, 798-808. doi: 10.1038/oby.2007.608
-
(2007)
Obesity
, vol.15
, pp. 798-808
-
-
Buettner, R.1
Schölmerich, J.2
Bollheimer, L.C.3
-
22
-
-
70450211783
-
Rodent models of diabetic cardiomyopathy
-
Bugger, H., and Abel, E. D. (2009). Rodent models of diabetic cardiomyopathy. Dis. Model. Mech. 2, 454-466. doi: 10.1242/dmm.001941
-
(2009)
Dis. Model. Mech.
, vol.2
, pp. 454-466
-
-
Bugger, H.1
Abel, E.D.2
-
23
-
-
77956572071
-
Mitochondria in the diabetic heart
-
Bugger, H., and Abel, E. D. (2010). Mitochondria in the diabetic heart. Cardiovasc. Res. 88, 229-240. doi: 10.1093/cvr/cvq239
-
(2010)
Cardiovasc. Res.
, vol.88
, pp. 229-240
-
-
Bugger, H.1
Abel, E.D.2
-
24
-
-
0027330056
-
A 13C-NMR study of glucose oxidation in the intact functioning rat heart following diabetes-induced cardiomyopathy
-
Chatham, J. C., and Forder, J. R. (1993). A 13C-NMR study of glucose oxidation in the intact functioning rat heart following diabetes-induced cardiomyopathy. J. Mol. Cell. Cardiol. 25, 1203-1213. doi: 10.1006/jmcc.1993.1133
-
(1993)
J. Mol. Cell. Cardiol.
, vol.25
, pp. 1203-1213
-
-
Chatham, J.C.1
Forder, J.R.2
-
25
-
-
0010288836
-
Relationship between cardiac function and substrate oxidation in hearts of diabetic rats
-
Chatham, J. C., and Forder, J. R. (1997). Relationship between cardiac function and substrate oxidation in hearts of diabetic rats. Am. J. Physiol. Heart Circ. Physiol. 273, H52-H58. doi: 10.1152/ajpheart.1997.273.1.H52
-
(1997)
Am. J. Physiol. Heart Circ. Physiol.
, vol.273
, pp. H52-H58
-
-
Chatham, J.C.1
Forder, J.R.2
-
26
-
-
0032848847
-
Impact of 1 wk of diabetes on the regulation of myocardial carbohydrate and fatty acid oxidation
-
Chatham, J. C., Gao, Z.-P., and Forder, J. R. (1999). Impact of 1 wk of diabetes on the regulation of myocardial carbohydrate and fatty acid oxidation. Am. J. Physiol. Endocrinol. Metab. 277, E342-E351. doi: 10.1152/ajpendo.1999.277.2.E342
-
(1999)
Am. J. Physiol. Endocrinol. Metab.
, vol.277
, pp. E342-E351
-
-
Chatham, J.C.1
Gao, Z.-P.2
Forder, J.R.3
-
27
-
-
0036274119
-
Cardiac carbohydrate metabolism in Zucker diabetic fatty rats
-
Chatham, J. C., and Seymour, A.-M. (2002). Cardiac carbohydrate metabolism in Zucker diabetic fatty rats. Cardiovasc. Res. 55, 104-112. doi: 10.1016/s0008-6363(02)00399-1
-
(2002)
Cardiovasc. Res.
, vol.55
, pp. 104-112
-
-
Chatham, J.C.1
Seymour, A.-M.2
-
28
-
-
13344259300
-
Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice
-
Chen, H., Charlat, O., Tartaglia, L. A., Woolf, E. A., Weng, X., Ellis, S. J., et al. (1996). Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell 84, 491-495. doi: 10.1016/s0092-8674(00)81294-5
-
(1996)
Cell
, vol.84
, pp. 491-495
-
-
Chen, H.1
Charlat, O.2
Tartaglia, L.A.3
Woolf, E.A.4
Weng, X.5
Ellis, S.J.6
-
29
-
-
84862137804
-
Ventricular assist device implantation corrects myocardial lipotoxicity, reverses insulin resistance, and normalizes cardiac metabolism in patients with advanced heart failure
-
Chokshi, A., Drosatos, K., Cheema, F. H., Ji, R., Khawaja, T., Yu, S., et al. (2012). Ventricular assist device implantation corrects myocardial lipotoxicity, reverses insulin resistance, and normalizes cardiac metabolism in patients with advanced heart failure. Circulation 125, 2844-2853. doi: 10.1161/CIRCULATIONAHA.111.060889
-
(2012)
Circulation
, vol.125
, pp. 2844-2853
-
-
Chokshi, A.1
Drosatos, K.2
Cheema, F.H.3
Ji, R.4
Khawaja, T.5
Yu, S.6
-
30
-
-
85019616260
-
Metabolic remodelling in diabetic cardiomyopathy
-
Chong, C.-R., Clarke, K., and Levelt, E. (2017). Metabolic remodelling in diabetic cardiomyopathy. Cardiovasc. Res. 113, 422-430. doi: 10.1093/cvr/cvx018
-
(2017)
Cardiovasc. Res.
, vol.113
, pp. 422-430
-
-
Chong, C.-R.1
Clarke, K.2
Levelt, E.3
-
31
-
-
79955537175
-
A high fat diet increases mitochondrial fatty acid oxidation and uncoupling to decrease efficiency in rat heart
-
Cole, M. A., Murray, A. J., Cochlin, L. E., Heather, L. C., McAleese, S., Knight, N. S., et al. (2011). A high fat diet increases mitochondrial fatty acid oxidation and uncoupling to decrease efficiency in rat heart. Basic Res. Cardiol. 106, 447-457. doi: 10.1007/s00395-011-0156-1
-
(2011)
Basic Res. Cardiol.
, vol.106
, pp. 447-457
-
-
Cole, M.A.1
Murray, A.J.2
Cochlin, L.E.3
Heather, L.C.4
McAleese, S.5
Knight, N.S.6
-
32
-
-
3042739406
-
Enhanced sarcolemmal FAT/CD36 content and triacylglycerol storage in cardiac myocytes from obese zucker rats
-
Coort, S. L. M., Hasselbaink, D. M., Koonen, D. P. Y., Willems, J., Coumans, W. A., Chabowski, A., et al. (2004). Enhanced sarcolemmal FAT/CD36 content and triacylglycerol storage in cardiac myocytes from obese zucker rats. Diabetes 53, 1655-1663. doi: 10.2337/diabetes.53.7.1655
-
(2004)
Diabetes
, vol.53
, pp. 1655-1663
-
-
Coort, S.L.M.1
Hasselbaink, D.M.2
Koonen, D.P.Y.3
Willems, J.4
Coumans, W.A.5
Chabowski, A.6
-
33
-
-
15444366991
-
Metabolic syndrome: A comprehensive perspective based on interactions between obesity, diabetes, and inflammation
-
Dandona, P., Aljada, A., Chaudhuri, A., Mohanty, P., and Garg, R. (2005). Metabolic syndrome: a comprehensive perspective based on interactions between obesity, diabetes, and inflammation. Circulation 111, 1448-1454. doi: 10.1161/01.CIR.0000158483.13093.9D
-
(2005)
Circulation
, vol.111
, pp. 1448-1454
-
-
Dandona, P.1
Aljada, A.2
Chaudhuri, A.3
Mohanty, P.4
Garg, R.5
-
34
-
-
8644285092
-
The role of glimepiride in the effective management of Type 2 diabetes
-
Davis, S. N. (2004). The role of glimepiride in the effective management of Type 2 diabetes. J. Diabetes Complicat. 18, 367-376. doi: 10.1016/j.jdiacomp.2004.07.001
-
(2004)
J. Diabetes Complicat.
, vol.18
, pp. 367-376
-
-
Davis, S.N.1
-
35
-
-
80054695683
-
Single dose streptozotocin induced diabetes: Considerations for study design in islet transplantation models
-
Deeds, M., Anderson, J., Armstrong, A., Gastineau, D., Hiddinga, H., Jahangir, A., et al. (2011). Single dose streptozotocin induced diabetes: considerations for study design in islet transplantation models. Lab. Anim. 45, 131-140. doi: 10.1258/la.2010.010090
-
(2011)
Lab. Anim.
, vol.45
, pp. 131-140
-
-
Deeds, M.1
Anderson, J.2
Armstrong, A.3
Gastineau, D.4
Hiddinga, H.5
Jahangir, A.6
-
36
-
-
0014116416
-
Concentrations of glycerides and phospholipids in rat heart and gastrocnemius muscles. Effects of alloxan-diabetes and perfusion
-
Denton, R. M., and Randle, P. J. (1967). Concentrations of glycerides and phospholipids in rat heart and gastrocnemius muscles. Effects of alloxan-diabetes and perfusion. Biochem. J. 104, 416-422. doi: 10.1042/bj1040416
-
(1967)
Biochem. J.
, vol.104
, pp. 416-422
-
-
Denton, R.M.1
Randle, P.J.2
-
38
-
-
85002781495
-
Evidence of glycolysis up-regulation and pyruvate mitochondrial oxidation mismatch during mechanical unloading of the failing human heart: Implications for cardiac reloading and conditioning
-
Diakos, N. A., Navankasattusas, S., Abel, E. D., Rutter, J., McCreath, L., Ferrin, P., et al. (2016). Evidence of glycolysis up-regulation and pyruvate mitochondrial oxidation mismatch during mechanical unloading of the failing human heart: implications for cardiac reloading and conditioning. JACC Basic Transl. Sci. 1, 432-444. doi: 10.1016/j.jacbts.2016.06.009
-
(2016)
JACC Basic Transl. Sci.
, vol.1
, pp. 432-444
-
-
Diakos, N.A.1
Navankasattusas, S.2
Abel, E.D.3
Rutter, J.4
McCreath, L.5
Ferrin, P.6
-
39
-
-
0038488294
-
Diastolic dysfunction is associated with altered myocardial metabolism in asymptomatic normotensive patients with well-controlled type 2 diabetes mellitus
-
Diamant, M., Lamb, H. J., Groeneveld, Y., Endert, E. L., Smit, J. W. A., Bax, J. J., et al. (2003). Diastolic dysfunction is associated with altered myocardial metabolism in asymptomatic normotensive patients with well-controlled type 2 diabetes mellitus. J. Am. Coll. Cardiol. 42, 328-335. doi: 10.1016/s0735-1097(03)00625-9
-
(2003)
J. Am. Coll. Cardiol.
, vol.42
, pp. 328-335
-
-
Diamant, M.1
Lamb, H.J.2
Groeneveld, Y.3
Endert, E.L.4
Smit, J.W.A.5
Bax, J.J.6
-
40
-
-
85053829816
-
Fatty acids prevent hypoxia-inducible factor-1α signaling through decreased succinate in diabetes
-
Dodd, M. S., Sousa Fialho, M., da, L., Montes Aparicio, C. N., Kerr, M., Timm, K. N., et al. (2018). Fatty acids prevent hypoxia-inducible factor-1α signaling through decreased succinate in diabetes. JACC Basic Transl. Sci. 3, 485-498. doi: 10.1016/j.jacbts.2018.04.005
-
(2018)
JACC Basic Transl. Sci.
, vol.3
, pp. 485-498
-
-
Dodd, M.S.1
Sousa Fialho, M.2
Da, L.3
Montes Aparicio, C.N.4
Kerr, M.5
Timm, K.N.6
-
41
-
-
85025078604
-
Changes of myocardial lipidomics profiling in a rat model of diabetic cardiomyopathy using UPLC/Q-TOF/MS analysis
-
Dong, S., Zhang, R., Liang, Y., Shi, J., Li, J., Shang, F., et al. (2017). Changes of myocardial lipidomics profiling in a rat model of diabetic cardiomyopathy using UPLC/Q-TOF/MS analysis. Diabetol. Metab. Syndr. 9:56. doi: 10.1186/s13098-017-0249-6
-
(2017)
Diabetol. Metab. Syndr.
, vol.9
, pp. 56
-
-
Dong, S.1
Zhang, R.2
Liang, Y.3
Shi, J.4
Li, J.5
Shang, F.6
-
42
-
-
85054932478
-
Berberine could ameliorate cardiac dysfunction via interfering myocardial lipidomic profiles in the rat model of diabetic cardiomyopathy
-
Dong, S., Zhang, S., Chen, Z., Zhang, R., Tian, L., Cheng, L., et al. (2018). Berberine could ameliorate cardiac dysfunction via interfering myocardial lipidomic profiles in the rat model of diabetic cardiomyopathy. Front. Physiol. 9:1042. doi: 10.3389/fphys.2018.01042
-
(2018)
Front. Physiol.
, vol.9
, pp. 1042
-
-
Dong, S.1
Zhang, S.2
Chen, Z.3
Zhang, R.4
Tian, L.5
Cheng, L.6
-
43
-
-
78650315006
-
Systems level studies of mammalian metabolomes: The roles of mass spectrometry and nuclear magnetic resonance spectroscopy
-
Dunn, W. B., Broadhurst, D. I., Atherton, H. J., Goodacre, R., and Griffin, J. L. (2011). Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy. Chem. Soc. Rev. 40, 387-426. doi: 10.1039/B906712B
-
(2011)
Chem. Soc. Rev.
, vol.40
, pp. 387-426
-
-
Dunn, W.B.1
Broadhurst, D.I.2
Atherton, H.J.3
Goodacre, R.4
Griffin, J.L.5
-
44
-
-
84861601268
-
Diabetic cardiomyopathy: Myth or reality?
-
Ernande, L., and Derumeaux, G. (2012). Diabetic cardiomyopathy: myth or reality? Arch. Cardiovasc. Dis. 105, 218-225. doi: 10.1016/j.acvd.2011.11.007
-
(2012)
Arch. Cardiovasc. Dis.
, vol.105
, pp. 218-225
-
-
Ernande, L.1
Derumeaux, G.2
-
45
-
-
84964608804
-
Shift to fatty substrate utilization in response to sodium-glucose cotransporter 2 inhibition in subjects without diabetes and patients with type 2 diabetes
-
Ferrannini, E., Baldi, S., Frascerra, S., Astiarraga, B., Heise, T., Bizzotto, R., et al. (2016). Shift to fatty substrate utilization in response to sodium-glucose cotransporter 2 inhibition in subjects without diabetes and patients with type 2 diabetes. Diabetes 65, 1190-1195. doi: 10.2337/db15-1356
-
(2016)
Diabetes
, vol.65
, pp. 1190-1195
-
-
Ferrannini, E.1
Baldi, S.2
Frascerra, S.3
Astiarraga, B.4
Heise, T.5
Bizzotto, R.6
-
46
-
-
0037417725
-
A critical role for PPARα-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: Modulation by dietary fat content
-
Finck, B. N., Han, X., Courtois, M., Aimond, F., Nerbonne, J. M., Kovacs, A., et al. (2003). A critical role for PPARα-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content. Proc. Natl. Acad. Sci. U.S.A. 100, 1226-1231. doi: 10.1073/pnas.0336724100
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 1226-1231
-
-
Finck, B.N.1
Han, X.2
Courtois, M.3
Aimond, F.4
Nerbonne, J.M.5
Kovacs, A.6
-
47
-
-
0026331625
-
Molecular mapping of the mouse ob mutation
-
Friedman, J. M., Leibel, R. L., Siegel, D. S., Walsh, J., and Bahary, N. (1991). Molecular mapping of the mouse ob mutation. Genomics 11, 1054-1062. doi: 10.1016/0888-7543(91)90032-A
-
(1991)
Genomics
, vol.11
, pp. 1054-1062
-
-
Friedman, J.M.1
Leibel, R.L.2
Siegel, D.S.3
Walsh, J.4
Bahary, N.5
-
48
-
-
61749086774
-
Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic β cells recapitulates neonatal diabetes
-
Girard, C. A., Wunderlich, F. T., Shimomura, K., Collins, S., Kaizik, S., Proks, P., et al. (2009). Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic β cells recapitulates neonatal diabetes. J. Clin. Invest. 119, 80-90. doi: 10.1172/JCI35772
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 80-90
-
-
Girard, C.A.1
Wunderlich, F.T.2
Shimomura, K.3
Collins, S.4
Kaizik, S.5
Proks, P.6
-
49
-
-
42549171517
-
Cardiac metabolism measured noninvasively by hyperpolarized 13C MRI
-
Golman, K., Petersson, J. S., Magnusson, P., Johansson, E., Åkeson, P., Chai, C.-M., et al. (2008). Cardiac metabolism measured noninvasively by hyperpolarized 13C MRI. Magn. Reson. Med. 59, 1005-1013. doi: 10.1002/mrm.21460
-
(2008)
Magn. Reson. Med.
, vol.59
, pp. 1005-1013
-
-
Golman, K.1
Petersson, J.S.2
Magnusson, P.3
Johansson, E.4
Åkeson, P.5
Chai, C.-M.6
-
50
-
-
80055026433
-
Metabolomics as a tool for cardiac research
-
Griffin, J. L., Atherton, H., Shockcor, J., and Atzori, L. (2011). Metabolomics as a tool for cardiac research. Nat. Rev. Cardiol. 8, 630-643. doi: 10.1038/nrcardio.2011.138
-
(2011)
Nat. Rev. Cardiol.
, vol.8
, pp. 630-643
-
-
Griffin, J.L.1
Atherton, H.2
Shockcor, J.3
Atzori, L.4
-
51
-
-
85012072430
-
Lipid zonation and phospholipid remodeling in nonalcoholic fatty liver disease
-
Hall, Z., Bond, N. J., Ashmore, T., Sanders, F., Ament, Z., Wang, X., et al. (2017). Lipid zonation and phospholipid remodeling in nonalcoholic fatty liver disease. Hepatology 65, 1165-1180. doi: 10.1002/hep.28953
-
(2017)
Hepatology
, vol.65
, pp. 1165-1180
-
-
Hall, Z.1
Bond, N.J.2
Ashmore, T.3
Sanders, F.4
Ament, Z.5
Wang, X.6
-
52
-
-
53149114140
-
Short-term flexibility of myocardial triglycerides and diastolic function in patients with type 2 diabetes mellitus
-
Hammer, S., van der Meer, R. W., Lamb, H. J., de Boer, H. H., Bax, J. J., de Roos, A., et al. (2008a). Short-term flexibility of myocardial triglycerides and diastolic function in patients with type 2 diabetes mellitus. Am. J. Physiol. Endocrinol. Metab. 295, E714-E718. doi: 10.1152/ajpendo.90413.2008
-
(2008)
Am. J. Physiol. Endocrinol. Metab.
, vol.295
, pp. E714-E718
-
-
Hammer, S.1
Van Der Meer, R.W.2
Lamb, H.J.3
De Boer, H.H.4
Bax, J.J.5
De Roos, A.6
-
53
-
-
39049116617
-
Progressive caloric restriction induces dose-dependent changes in myocardial triglyceride content and diastolic function in healthy men
-
Hammer, S., van der Meer, R. W., Lamb, H. J., Schär, M., de Roos, A., Smit, J. W. A., et al. (2008b). Progressive caloric restriction induces dose-dependent changes in myocardial triglyceride content and diastolic function in healthy men. J. Clin. Endocrinol. Metab. 93, 497-503. doi: 10.1210/jc.2007-2015
-
(2008)
J. Clin. Endocrinol. Metab.
, vol.93
, pp. 497-503
-
-
Hammer, S.1
Van Der Meer, R.W.2
Lamb, H.J.3
Schär, M.4
De Roos, A.5
Smit, J.W.A.6
-
54
-
-
29244477536
-
Shotgun lipidomics identifies cardiolipin depletion in diabetic myocardium linking altered substrate utilization with mitochondrial dysfunction
-
Han, X., Yang, J., Cheng, H., Yang, K., Abendschein, D. R., and Gross, R. W. (2005). Shotgun lipidomics identifies cardiolipin depletion in diabetic myocardium linking altered substrate utilization with mitochondrial dysfunction. Biochemistry 44, 16684-16694. doi: 10.1021/bi051908a
-
(2005)
Biochemistry
, vol.44
, pp. 16684-16694
-
-
Han, X.1
Yang, J.2
Cheng, H.3
Yang, K.4
Abendschein, D.R.5
Gross, R.W.6
-
55
-
-
34249672811
-
Alterations in myocardial cardiolipin content and composition occur at the very earliest stages of diabetes:? A shotgun lipidomics study
-
Han, X., Yang, J., Yang, K., Zhao, Z., Abendschein, D. R., and Gross, R. W. (2007). Alterations in myocardial cardiolipin content and composition occur at the very earliest stages of diabetes:? a shotgun lipidomics study. Biochemistry 46, 6417-6428. doi: 10.1021/bi7004015
-
(2007)
Biochemistry
, vol.46
, pp. 6417-6428
-
-
Han, X.1
Yang, J.2
Yang, K.3
Zhao, Z.4
Abendschein, D.R.5
Gross, R.W.6
-
56
-
-
31644445201
-
Increased myocardial fatty acid metabolism in patients with type 1 diabetes mellitus
-
Herrero, P., Peterson, L. R., McGill, J. B., Matthew, S., Lesniak, D., Dence, C., et al. (2006). Increased myocardial fatty acid metabolism in patients with type 1 diabetes mellitus. J. Am. Coll. Cardiol. 47, 598-604. doi: 10.1016/j.jacc.2005.09.030
-
(2006)
J. Am. Coll. Cardiol.
, vol.47
, pp. 598-604
-
-
Herrero, P.1
Peterson, L.R.2
McGill, J.B.3
Matthew, S.4
Lesniak, D.5
Dence, C.6
-
57
-
-
33947237562
-
The chemical nature of heart failure
-
Herrmann, G., and Decherd, G. M. Jr. (1939). The chemical nature of heart failure. Ann. Intern. Med. 12, 1233-1244. doi: 10.7326/0003-4819-12-8-1233
-
(1939)
Ann. Intern. Med.
, vol.12
, pp. 1233-1244
-
-
Herrmann, G.1
Decherd, G.M.2
-
58
-
-
79953214035
-
A high-fat diet impairs cardiac high-energy phosphate metabolism and cognitive function in healthy human subjects
-
Holloway, C. J., Cochlin, L. E., Emmanuel, Y., Murray, A., Codreanu, I., Edwards, L. M., et al. (2011). A high-fat diet impairs cardiac high-energy phosphate metabolism and cognitive function in healthy human subjects. Am. J. Clin. Nutr. 93, 748-755. doi: 10.3945/ajcn.110.002758
-
(2011)
Am. J. Clin. Nutr.
, vol.93
, pp. 748-755
-
-
Holloway, C.J.1
Cochlin, L.E.2
Emmanuel, Y.3
Murray, A.4
Codreanu, I.5
Edwards, L.M.6
-
59
-
-
85007240955
-
Diabetic cardiomyopathy: Does the type of diabetes matter?
-
Hölscher, M. E., Bode, C., and Bugger, H. (2016). Diabetic cardiomyopathy: does the type of diabetes matter? Int. J. Mol. Sci. 17:2136. doi: 10.3390/ijms17122136
-
(2016)
Int. J. Mol. Sci.
, vol.17
, pp. 2136
-
-
Hölscher, M.E.1
Bode, C.2
Bugger, H.3
-
60
-
-
33644784921
-
Increased myocardial oxygen consumption reduces cardiac efficiency in diabetic mice
-
How, O.-J., Aasum, E., Severson, D. L., Chan, W. Y. A., Essop, M. F., and Larsen, T. S. (2006). Increased myocardial oxygen consumption reduces cardiac efficiency in diabetic mice. Diabetes 55, 466-473. doi: 10.2337/diabetes.55.02.06.db05-1164
-
(2006)
Diabetes
, vol.55
, pp. 466-473
-
-
How, O.-J.1
Aasum, E.2
Severson, D.L.3
Chan, W.Y.A.4
Essop, M.F.5
Larsen, T.S.6
-
61
-
-
0014004384
-
Diabetes, a new mutation in the mouse
-
Hummel, K. P., Dickie, M. M., and Coleman, D. L. (1966). Diabetes, a new mutation in the mouse. Science 153, 1127-1128. doi: 10.1126/science.153.3740.1127
-
(1966)
Science
, vol.153
, pp. 1127-1128
-
-
Hummel, K.P.1
Dickie, M.M.2
Coleman, D.L.3
-
62
-
-
84964253599
-
Human amylin proteotoxicity impairs protein biosynthesis, and alters major cellular signaling pathways in the heart, brain and liver of humanized diabetic rat model in vivo
-
Ilaiwy, A., Liu, M., Parry, T. L., Bain, J. R., Newgard, C. B., Schisler, J. C., et al. (2016). Human amylin proteotoxicity impairs protein biosynthesis, and alters major cellular signaling pathways in the heart, brain and liver of humanized diabetic rat model in vivo. Metabolomics 12:95. doi: 10.1007/s11306-016-1022-9
-
(2016)
Metabolomics
, vol.12
, pp. 95
-
-
Ilaiwy, A.1
Liu, M.2
Parry, T.L.3
Bain, J.R.4
Newgard, C.B.5
Schisler, J.C.6
-
63
-
-
0028873551
-
Elevated lipid peroxidation and Vitamin E-quinone levels in heart ventricles of streptozotocin-treated diabetic rats
-
Jain, S. K., and Levine, S. N. (1995). Elevated lipid peroxidation and vitamin E-quinone levels in heart ventricles of streptozotocin-treated diabetic rats. Free Radic. Biol. Med. 18, 337-341. doi: 10.1016/0891-5849(94)00114-Y
-
(1995)
Free Radic. Biol. Med.
, vol.18
, pp. 337-341
-
-
Jain, S.K.1
Levine, S.N.2
-
64
-
-
84870663187
-
Effects of insulin therapy on myocardial lipid content and cardiac geometry in patients with type-2 diabetes mellitus
-
Jankovic, D., Winhofer, Y., Promintzer-Schifferl, M., Wohlschläger-Krenn, E., Anderwald, C. H., Wolf, P., et al. (2012). Effects of insulin therapy on myocardial lipid content and cardiac geometry in patients with type-2 diabetes mellitus. PLoS One 7:e50077. doi: 10.1371/journal.pone.0050077
-
(2012)
PLoS One
, vol.7
-
-
Jankovic, D.1
Winhofer, Y.2
Promintzer-Schifferl, M.3
Wohlschläger-Krenn, E.4
Anderwald, C.H.5
Wolf, P.6
-
65
-
-
0028793745
-
Substrate selection in the isolated working rat heart: Effects of reperfusion, afterload, and concentration
-
Jeffrey, F. M., Diczku, V., Sherry, A. D., and Malloy, C. R. (1995). Substrate selection in the isolated working rat heart: effects of reperfusion, afterload, and concentration. Basic Res. Cardiol. 90, 388-396. doi: 10.1007/BF00788500
-
(1995)
Basic Res. Cardiol.
, vol.90
, pp. 388-396
-
-
Jeffrey, F.M.1
Diczku, V.2
Sherry, A.D.3
Malloy, C.R.4
-
66
-
-
85044730815
-
Diabetic cardiomyopathy: An update of mechanisms contributing to this clinical entity
-
Jia, G., Hill, M. A., and Sowers, J. R. (2018). Diabetic cardiomyopathy: an update of mechanisms contributing to this clinical entity. Circ. Res. 122, 624-638. doi: 10.1161/CIRCRESAHA.117.311586
-
(2018)
Circ. Res.
, vol.122
, pp. 624-638
-
-
Jia, G.1
Hill, M.A.2
Sowers, J.R.3
-
67
-
-
85013469521
-
Activation of PPAR-α in the early stage of heart failure maintained myocardial function and energetics in pressure-overload heart failure
-
Kaimoto, S., Hoshino, A., Ariyoshi, M., Okawa, Y., Tateishi, S., Ono, K., et al. (2017). Activation of PPAR-α in the early stage of heart failure maintained myocardial function and energetics in pressure-overload heart failure. Am. J. Physiol. Heart Circ. Physiol. 312, H305-H313. doi: 10.1152/ajpheart.00553.2016
-
(2017)
Am. J. Physiol. Heart Circ. Physiol.
, vol.312
, pp. H305-H313
-
-
Kaimoto, S.1
Hoshino, A.2
Ariyoshi, M.3
Okawa, Y.4
Tateishi, S.5
Ono, K.6
-
68
-
-
33751546348
-
Myocardial triglyceride content and epicardial fat mass in human obesity: Relationship to left ventricular function and serum free fatty acid levels
-
Kankaanpää, M., Lehto, H.-R., Pärkkä, J. P., Komu, M., Viljanen, A., Ferrannini, E., et al. (2006). Myocardial triglyceride content and epicardial fat mass in human obesity: relationship to left ventricular function and serum free fatty acid levels. J. Clin. Endocrinol. Metab. 91, 4689-4695. doi: 10.1210/jc.2006-0584
-
(2006)
J. Clin. Endocrinol. Metab.
, vol.91
, pp. 4689-4695
-
-
Kankaanpää, M.1
Lehto, H.-R.2
Pärkkä, J.P.3
Komu, M.4
Viljanen, A.5
Ferrannini, E.6
-
69
-
-
0026343898
-
Quantitation of acyl-CoA and acylcarnitine esters accumulated during abnormal mitochondrial fatty acid oxidation
-
Kler, R. S., Jackson, S., Bartlett, K., Bindoff, L. A., Eaton, S., Pourfarzam, M., et al. (1991). Quantitation of acyl-CoA and acylcarnitine esters accumulated during abnormal mitochondrial fatty acid oxidation. J. Biol. Chem. 266, 22932-22938.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 22932-22938
-
-
Kler, R.S.1
Jackson, S.2
Bartlett, K.3
Bindoff, L.A.4
Eaton, S.5
Pourfarzam, M.6
-
70
-
-
0020626828
-
Defective oxidative metabolism of heart mitochondria from genetically diabetic mice
-
Kuo, T. H., Moore, K. H., Giacomelli, F., and Wiener, J. (1983). Defective oxidative metabolism of heart mitochondria from genetically diabetic mice. Diabetes 32, 781-787. doi: 10.2337/diab.32.9.781
-
(1983)
Diabetes
, vol.32
, pp. 781-787
-
-
Kuo, T.H.1
Moore, K.H.2
Giacomelli, F.3
Wiener, J.4
-
71
-
-
0030846522
-
Changes in microsomal membrane phospholipids and fatty acids and in activities of membrane-bound enzyme in diabetic rat heart
-
Kuwahara, Y., Yanagishita, T., Konno, N., and Katagiri, T. (1997). Changes in microsomal membrane phospholipids and fatty acids and in activities of membrane-bound enzyme in diabetic rat heart. Basic Res. Cardiol. 92, 214-222. doi: 10.1007/BF00788516
-
(1997)
Basic Res. Cardiol.
, vol.92
, pp. 214-222
-
-
Kuwahara, Y.1
Yanagishita, T.2
Konno, N.3
Katagiri, T.4
-
72
-
-
65449179559
-
Functional assessment of isolated mitochondria in vitro
-
Lanza, I. R., and Nair, K. S. (2009). Functional assessment of isolated mitochondria in vitro. Methods Enzymol. 457, 349-372. doi: 10.1016/S0076-6879(09)05020-4
-
(2009)
Methods Enzymol
, vol.457
, pp. 349-372
-
-
Lanza, I.R.1
Nair, K.S.2
-
73
-
-
42549169797
-
Metabolic (In)flexibility of the diabetic heart
-
Larsen, T. S., and Aasum, E. (2008). Metabolic (In)flexibility of the diabetic heart. Cardiovasc. Drugs Ther. 22, 91-95. doi: 10.1007/s10557-008-6083-1
-
(2008)
Cardiovasc. Drugs Ther.
, vol.22
, pp. 91-95
-
-
Larsen, T.S.1
Aasum, E.2
-
74
-
-
84977838083
-
Increasing pyruvate dehydrogenase flux as a treatment for diabetic cardiomyopathy: A combined 13C hyperpolarized magnetic resonance and echocardiography study
-
Le Page, L. M., Rider, O. J., Lewis, A. J., Ball, V., Clarke, K., Johansson, E., et al. (2015). Increasing pyruvate dehydrogenase flux as a treatment for diabetic cardiomyopathy: a combined 13C hyperpolarized magnetic resonance and echocardiography study. Diabetes 64, 2735-2743. doi: 10.2337/db14-1560
-
(2015)
Diabetes
, vol.64
, pp. 2735-2743
-
-
Le Page, L.M.1
Rider, O.J.2
Lewis, A.J.3
Ball, V.4
Clarke, K.5
Johansson, E.6
-
75
-
-
84879375034
-
Cardiovascular changes in animal models of metabolic syndrome
-
Lehnen, A. M., Rodrigues, B., Irigoyen, M. C., De Angelis, K., and Schaan, B. D. (2013). Cardiovascular changes in animal models of metabolic syndrome. J. Diabetes Res. 2013:761314. doi: 10.1155/2013/761314
-
(2013)
J. Diabetes Res.
, vol.2013
, pp. 761314
-
-
Lehnen, A.M.1
Rodrigues, B.2
Irigoyen, M.C.3
De Angelis, K.4
Schaan, B.D.5
-
76
-
-
37549029242
-
The mechanisms of alloxan- And streptozotocin-induced diabetes
-
Lenzen, S. (2008). The mechanisms of alloxan- and streptozotocin-induced diabetes. Diabetologia 51, 216-226. doi: 10.1007/s00125-007-0886-7
-
(2008)
Diabetologia
, vol.51
, pp. 216-226
-
-
Lenzen, S.1
-
77
-
-
84962173633
-
Relationship between left ventricular structural and metabolic remodeling in type 2 diabetes
-
Levelt, E., Mahmod, M., Piechnik, S. K., Ariga, R., Francis, J. M., Rodgers, C. T., et al. (2016a). Relationship between left ventricular structural and metabolic remodeling in type 2 diabetes. Diabetes 65, 44-52. doi: 10.2337/db15-0627
-
(2016)
Diabetes
, vol.65
, pp. 44-52
-
-
Levelt, E.1
Mahmod, M.2
Piechnik, S.K.3
Ariga, R.4
Francis, J.M.5
Rodgers, C.T.6
-
78
-
-
85015953289
-
Cardiac energetics, oxygenation, and perfusion during increased workload in patients with type 2 diabetes mellitus
-
Levelt, E., Rodgers, C. T., Clarke, W. T., Mahmod, M., Ariga, R., Francis, J. M., et al. (2016b). Cardiac energetics, oxygenation, and perfusion during increased workload in patients with type 2 diabetes mellitus. Eur. Heart J. 37, 3461-3469. doi: 10.1093/eurheartj/ehv442
-
(2016)
Eur. Heart J.
, vol.37
, pp. 3461-3469
-
-
Levelt, E.1
Rodgers, C.T.2
Clarke, W.T.3
Mahmod, M.4
Ariga, R.5
Francis, J.M.6
-
79
-
-
50949096938
-
Mice deficient in mitochondrial glycerol-3-phosphate acyltransferase-1 have diminished myocardial triacylglycerol accumulation during lipogenic diet and altered phospholipid fatty acid composition
-
Lewin, T. M., de Jong, H., Schwerbrock, N. J. M., Hammond, L. E., Watkins, S. M., Combs, T. P., et al. (2008). Mice deficient in mitochondrial glycerol-3-phosphate acyltransferase-1 have diminished myocardial triacylglycerol accumulation during lipogenic diet and altered phospholipid fatty acid composition. Biochim. Biophys. Acta Mol. Cell Biol. Lipids 1781, 352-358. doi: 10.1016/j.bbalip.2008.05.001
-
(2008)
Biochim. Biophys. Acta Mol. Cell Biol. Lipids
, vol.1781
, pp. 352-358
-
-
Lewin, T.M.1
De Jong, H.2
Schwerbrock, N.J.M.3
Hammond, L.E.4
Watkins, S.M.5
Combs, T.P.6
-
80
-
-
84929094858
-
Triptolide improves systolic function and myocardial energy metabolism of diabetic cardiomyopathy in streptozotocin-induced diabetic rats
-
Liang, Z., Leo, S., Wen, H., Ouyang, M., Jiang, W., and Yang, K. (2015). Triptolide improves systolic function and myocardial energy metabolism of diabetic cardiomyopathy in streptozotocin-induced diabetic rats. BMC Cardiovasc. Disord. 15:42. doi: 10.1186/s12872-015-0030-4
-
(2015)
BMC Cardiovasc. Disord.
, vol.15
, pp. 42
-
-
Liang, Z.1
Leo, S.2
Wen, H.3
Ouyang, M.4
Jiang, W.5
Yang, K.6
-
81
-
-
84868095524
-
Overview of animal models of obesity
-
Lutz, T. A., and Woods, S. C. (2012). Overview of animal models of obesity. Curr. Protoc. Pharmacol. 58, 5.61.1-5.61.18. doi: 10.1002/0471141755.ph0561s58
-
(2012)
Curr. Protoc. Pharmacol.
, vol.58
, pp. 5611-56118
-
-
Lutz, T.A.1
Woods, S.C.2
-
82
-
-
84884680593
-
Cardiac metabolism in a new rat model of type 2 diabetes using high-fat diet with low dose streptozotocin
-
Mansor, L. S., Gonzalez, E. R., Cole, M. A., Tyler, D. J., Beeson, J. H., Clarke, K., et al. (2013). Cardiac metabolism in a new rat model of type 2 diabetes using high-fat diet with low dose streptozotocin. Cardiovasc. Diabetol. 12:136. doi: 10.1186/1475-2840-12-136
-
(2013)
Cardiovasc. Diabetol.
, vol.12
, pp. 136
-
-
Mansor, L.S.1
Gonzalez, E.R.2
Cole, M.A.3
Tyler, D.J.4
Beeson, J.H.5
Clarke, K.6
-
83
-
-
0030902933
-
Increased oxysterol contents in diabetic rat hearts: Their involvement in diabetic cardiomyopathy
-
Matsui, H., Okumura, K., Mukawa, H., Hibino, M., Toki, Y., and Ito, T. (1997). Increased oxysterol contents in diabetic rat hearts: their involvement in diabetic cardiomyopathy. Can. J. Cardiol. 13, 373-379.
-
(1997)
Can. J. Cardiol.
, vol.13
, pp. 373-379
-
-
Matsui, H.1
Okumura, K.2
Mukawa, H.3
Hibino, M.4
Toki, Y.5
Ito, T.6
-
84
-
-
34548385838
-
Cardiac steatosis in diabetes mellitus: A 1H-magnetic resonance spectroscopy study
-
McGavock, J. M., Lingvay, I., Zib, I., Tillery, T., Salas, N., Unger, R., et al. (2007). Cardiac steatosis in diabetes mellitus: a 1H-magnetic resonance spectroscopy study. Circulation 116, 1170-1175. doi: 10.1161/CIRCULATIONAHA.106.645614
-
(2007)
Circulation
, vol.116
, pp. 1170-1175
-
-
McGavock, J.M.1
Lingvay, I.2
Zib, I.3
Tillery, T.4
Salas, N.5
Unger, R.6
-
85
-
-
84855968181
-
MALDI mass spectrometric imaging of cardiac tissue following myocardial infarction in a rat coronary artery ligation model
-
Menger, R. F., Stutts, W. L., Anbukumar, D. S., Bowden, J. A., Ford, D. A., and Yost, R. A. (2012). MALDI mass spectrometric imaging of cardiac tissue following myocardial infarction in a rat coronary artery ligation model. Anal. Chem. 84, 1117-1125. doi: 10.1021/ac202779h
-
(2012)
Anal. Chem.
, vol.84
, pp. 1117-1125
-
-
Menger, R.F.1
Stutts, W.L.2
Anbukumar, D.S.3
Bowden, J.A.4
Ford, D.A.5
Yost, R.A.6
-
86
-
-
84959223174
-
Hyperpolarization MRI
-
Miloushev, V. Z., Keshari, K. R., and Holodny, A. I. (2016). Hyperpolarization MRI. Top. Magn. Reson. Imaging 25, 31-37. doi: 10.1097/RMR.0000000000000076
-
(2016)
Top. Magn. Reson. Imaging
, vol.25
, pp. 31-37
-
-
Miloushev, V.Z.1
Keshari, K.R.2
Holodny, A.I.3
-
87
-
-
4143091440
-
Myocardial insulin resistance associated with chronic hypertriglyceridemia and increased FFA levels in type 2 diabetic patients
-
Monti, L. D., Landoni, C., Setola, E., Galluccio, E., Lucotti, P., Sandoli, E. P., et al. (2004). Myocardial insulin resistance associated with chronic hypertriglyceridemia and increased FFA levels in type 2 diabetic patients. Am. J. Physiol. Heart Circ. Physiol. 287, H1225-H1231. doi: 10.1152/ajpheart.00629.2003
-
(2004)
Am. J. Physiol. Heart Circ. Physiol.
, vol.287
, pp. H1225-H1231
-
-
Monti, L.D.1
Landoni, C.2
Setola, E.3
Galluccio, E.4
Lucotti, P.5
Sandoli, E.P.6
-
88
-
-
85079121634
-
Worldwide trends in diabetes since 1980: A pooled analysis of 751 population-based studies with 44 million participants
-
NCD Risk Factor Collaboration (NCD-RisC) (2016). Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 44 million participants. Lancet 387, 1513-1530. doi: 10.1016/s0140-6736(16)00618-8
-
(2016)
Lancet
, vol.387
, pp. 1513-1530
-
-
-
89
-
-
33947239659
-
The failing heart - An engine out of fuel
-
Neubauer, S. (2007). The failing heart - an engine out of fuel. N. Engl. J. Med. 356, 1140-1151. doi: 10.1056/NEJMra063052
-
(2007)
N. Engl. J. Med.
, vol.356
, pp. 1140-1151
-
-
Neubauer, S.1
-
90
-
-
0030819144
-
Myocardial phosphocreatine-to-ATP ratio is a predictor of mortality in patients with dilated cardiomyopathy
-
Neubauer, S., Horn, M., Cramer, M., Harre, K., Newell, J. B., Peters, W., et al. (1997). Myocardial phosphocreatine-to-ATP ratio is a predictor of mortality in patients with dilated cardiomyopathy. Circulation 96, 2190-2196. doi: 10.1161/01.CIR.96.7.2190
-
(1997)
Circulation
, vol.96
, pp. 2190-2196
-
-
Neubauer, S.1
Horn, M.2
Cramer, M.3
Harre, K.4
Newell, J.B.5
Peters, W.6
-
91
-
-
78650683294
-
Myocardial steatosis and biventricular strain and strain rate imaging in patients with type 2 diabetes mellitus
-
Ng, A. C. T., Delgado, V., Bertini, M., van der Meer, R. W., Rijzewijk, L. J., Hooi Ewe, S., et al. (2010). Myocardial steatosis and biventricular strain and strain rate imaging in patients with type 2 diabetes mellitus. Circulation 122, 2538-2544. doi: 10.1161/CIRCULATIONAHA.110.955542
-
(2010)
Circulation
, vol.122
, pp. 2538-2544
-
-
Ng, A.C.T.1
Delgado, V.2
Bertini, M.3
Van Der Meer, R.W.4
Rijzewijk, L.J.5
Hooi Ewe, S.6
-
92
-
-
84887340400
-
Cardiac steatosis and left ventricular function in men with metabolic syndrome
-
Nyman, K., Granér, M., Pentikäinen, M. O., Lundbom, J., Hakkarainen, A., Sirén, R., et al. (2013). Cardiac steatosis and left ventricular function in men with metabolic syndrome. J. Cardiovasc. Magn. Reson. 15:103. doi: 10.1186/1532-429X-15-103
-
(2013)
J. Cardiovasc. Magn. Reson.
, vol.15
, pp. 103
-
-
Nyman, K.1
Granér, M.2
Pentikäinen, M.O.3
Lundbom, J.4
Hakkarainen, A.5
Sirén, R.6
-
93
-
-
84946544768
-
Mitochondrial responses to extreme environments: Insights from metabolomics
-
O'Brien, K. A., Griffin, J. L., Murray, A. J., and Edwards, L. M. (2015). Mitochondrial responses to extreme environments: insights from metabolomics. Extrem Physiol. Med. 4:7. doi: 10.1186/s13728-015-0026-9
-
(2015)
Extrem Physiol. Med.
, vol.4
, pp. 7
-
-
O'Brien, K.A.1
Griffin, J.L.2
Murray, A.J.3
Edwards, L.M.4
-
94
-
-
33645093211
-
Accelerated triacylglycerol turnover kinetics in hearts of diabetic rats include evidence for compartmented lipid storage
-
O'Donnell, J. M., Zampino, M., Alpert, N. M., Fasano, M. J., Geenen, D. L., and Lewandowski, E. D. (2006). Accelerated triacylglycerol turnover kinetics in hearts of diabetic rats include evidence for compartmented lipid storage. Am. J. Physiol. Endocrinol. Metab. 290, E448-E455. doi: 10.1152/ajpendo.00139.2005
-
(2006)
Am. J. Physiol. Endocrinol. Metab.
, vol.290
, pp. E448-E455
-
-
O'Donnell, J.M.1
Zampino, M.2
Alpert, N.M.3
Fasano, M.J.4
Geenen, D.L.5
Lewandowski, E.D.6
-
95
-
-
84893919243
-
Prevention of type 2 diabetes mellitus: Is it feasible?
-
Palermo, A., Maggi, D., Maurizi, A. R., Pozzilli, P., and Buzzetti, R. (2014). Prevention of type 2 diabetes mellitus: is it feasible? Diabetes Metab. Res. Rev. 30, 4-12. doi: 10.1002/dmrr.2513
-
(2014)
Diabetes Metab. Res. Rev.
, vol.30
, pp. 4-12
-
-
Palermo, A.1
Maggi, D.2
Maurizi, A.R.3
Pozzilli, P.4
Buzzetti, R.5
-
96
-
-
84896545275
-
Diabetic cardiomyopathy: Pathophysiology, diagnostic evaluation and management
-
Pappachan, J. M., Varughese, G. I., Sriraman, R., and Arunagirinathan, G. (2013). Diabetic cardiomyopathy: pathophysiology, diagnostic evaluation and management. World J. Diabetes 4, 177-189. doi: 10.4239/wjd.v4.i5.177
-
(2013)
World J. Diabetes
, vol.4
, pp. 177-189
-
-
Pappachan, J.M.1
Varughese, G.I.2
Sriraman, R.3
Arunagirinathan, G.4
-
97
-
-
34249903324
-
Abnormal left ventricular energy metabolism in obese men with preserved systolic and diastolic functions is associated with insulin resistance
-
Perseghin, G., Ntali, G., Cobelli, F. D., Lattuada, G., Esposito, A., Belloni, E., et al. (2007). Abnormal left ventricular energy metabolism in obese men with preserved systolic and diastolic functions is associated with insulin resistance. Diabetes Care 30, 1520-1526. doi: 10.2337/dc06-2429
-
(2007)
Diabetes Care
, vol.30
, pp. 1520-1526
-
-
Perseghin, G.1
Ntali, G.2
Cobelli, F.D.3
Lattuada, G.4
Esposito, A.5
Belloni, E.6
-
98
-
-
2442492971
-
Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women
-
Peterson, L. R., Herrero, P., Schechtman, K. B., Racette, S. B., Waggoner, A. D., Kisrieva-Ware, Z., et al. (2004). Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women. Circulation 109, 2191-2196. doi: 10.1161/01.CIR.0000127959.28627.F8
-
(2004)
Circulation
, vol.109
, pp. 2191-2196
-
-
Peterson, L.R.1
Herrero, P.2
Schechtman, K.B.3
Racette, S.B.4
Waggoner, A.D.5
Kisrieva-Ware, Z.6
-
99
-
-
50549202600
-
The glucose fatty acid cycle its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
-
Randle, P. J., Garland, P. B., Hales, C. N., and Newsholme, E. A. (1963). The glucose fatty acid cycle its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet 281, 785-789. doi: 10.1016/S0140-6736(63)91500-9
-
(1963)
Lancet
, vol.281
, pp. 785-789
-
-
Randle, P.J.1
Garland, P.B.2
Hales, C.N.3
Newsholme, E.A.4
-
100
-
-
17144404203
-
Animal models of diabetes mellitus
-
Rees, D. A., and Alcolado, J. C. (2005). Animal models of diabetes mellitus. Diabet. Med. 22, 359-370. doi: 10.1111/j.1464-5491.2005.01499.x
-
(2005)
Diabet. Med.
, vol.22
, pp. 359-370
-
-
Rees, D.A.1
Alcolado, J.C.2
-
101
-
-
0014852350
-
Effect of a high fat diet on the metabolism and mechanical behaviour of the isolated rat heart
-
Reid, J. V. O., Lochner, A., and Brink, A. J. (1970). Effect of a high fat diet on the metabolism and mechanical behaviour of the isolated rat heart. J. Mol. Cell. Cardiol. 1, 209-220. doi: 10.1016/0022-2828(70)90002-7
-
(1970)
J. Mol. Cell. Cardiol.
, vol.1
, pp. 209-220
-
-
Reid, J.V.O.1
Lochner, A.2
Brink, A.J.3
-
102
-
-
27144543513
-
Determination of triglyceride in the human myocardium by magnetic resonance spectroscopy: Reproducibility and sensitivity of the method
-
Reingold, J. S., McGavock, J. M., Kaka, S., Tillery, T., Victor, R. G., and Szczepaniak, L. S. (2005). Determination of triglyceride in the human myocardium by magnetic resonance spectroscopy: reproducibility and sensitivity of the method. Am. J. Physiol. Endocrinol. Metab. 289, E935-E939. doi: 10.1152/ajpendo.00095.2005
-
(2005)
Am. J. Physiol. Endocrinol. Metab.
, vol.289
, pp. E935-E939
-
-
Reingold, J.S.1
McGavock, J.M.2
Kaka, S.3
Tillery, T.4
Victor, R.G.5
Szczepaniak, L.S.6
-
103
-
-
84893662844
-
Effects of weight loss on myocardial energetics and diastolic function in obesity
-
Rider, O. J., Francis, J. M., Tyler, D., Byrne, J., Clarke, K., and Neubauer, S. (2013). Effects of weight loss on myocardial energetics and diastolic function in obesity. Int. J. Cardiovasc. Imaging 29, 1043-1050. doi: 10.1007/s10554-012-0174-6
-
(2013)
Int. J. Cardiovasc. Imaging
, vol.29
, pp. 1043-1050
-
-
Rider, O.J.1
Francis, J.M.2
Tyler, D.3
Byrne, J.4
Clarke, K.5
Neubauer, S.6
-
104
-
-
70350459556
-
Altered myocardial substrate metabolism and decreased diastolic function in nonischemic human diabetic cardiomyopathy: Studies with cardiac positron emission tomography and magnetic resonance imaging
-
Rijzewijk, L. J., van der Meer, R. W., Lamb, H. J., de Jong, H. W. A. M., Lubberink, M., Romijn, J. A., et al. (2009). Altered myocardial substrate metabolism and decreased diastolic function in nonischemic human diabetic cardiomyopathy: studies with cardiac positron emission tomography and magnetic resonance imaging. J. Am. Coll. Cardiol. 54, 1524-1532. doi: 10.1016/j.jacc.2009.04.074
-
(2009)
J. Am. Coll. Cardiol.
, vol.54
, pp. 1524-1532
-
-
Rijzewijk, L.J.1
Van Der Meer, R.W.2
Lamb, H.J.3
De Jong, H.W.A.M.4
Lubberink, M.5
Romijn, J.A.6
-
105
-
-
55949119360
-
Myocardial steatosis is an independent predictor of diastolic dysfunction in type 2 diabetes mellitus
-
Rijzewijk, L. J., van der Meer, R. W., Smit, J. W. A., Diamant, M., Bax, J. J., Hammer, S., et al. (2008). Myocardial steatosis is an independent predictor of diastolic dysfunction in type 2 diabetes mellitus. J. Am. Coll. Cardiol. 52, 1793-1799. doi: 10.1016/j.jacc.2008.07.062
-
(2008)
J. Am. Coll. Cardiol.
, vol.52
, pp. 1793-1799
-
-
Rijzewijk, L.J.1
Van Der Meer, R.W.2
Smit, J.W.A.3
Diamant, M.4
Bax, J.J.5
Hammer, S.6
-
106
-
-
85047767414
-
Cardiac dysfunction and metabolic inflexibility in a mouse model of diabetes without dyslipidemia
-
Rohm, M., Savic, D., Ball, V., Curtis, M. K., Bonham, S., Fischer, R., et al. (2018). Cardiac dysfunction and metabolic inflexibility in a mouse model of diabetes without dyslipidemia. Diabetes 67, 1057-1067. doi: 10.2337/db17-1195
-
(2018)
Diabetes
, vol.67
, pp. 1057-1067
-
-
Rohm, M.1
Savic, D.2
Ball, V.3
Curtis, M.K.4
Bonham, S.5
Fischer, R.6
-
107
-
-
77956586695
-
Mitochondria in heart failure
-
Rosca, M. G., and Hoppel, C. L. (2010). Mitochondria in heart failure. Cardiovasc. Res. 88, 40-50. doi: 10.1093/cvr/cvq240
-
(2010)
Cardiovasc. Res.
, vol.88
, pp. 40-50
-
-
Rosca, M.G.1
Hoppel, C.L.2
-
108
-
-
0017648112
-
Studies of streptozotocin-induced insulitis and diabetes
-
Rossini, A. A., Like, A. A., Chick, W. L., Appel, M. C., and Cahill, G. F. (1977). Studies of streptozotocin-induced insulitis and diabetes. Proc. Natl. Acad. Sci. U.S.A. 74, 2485-2489. doi: 10.1073/pnas.74.6.2485
-
(1977)
Proc. Natl. Acad. Sci. U.S.A.
, vol.74
, pp. 2485-2489
-
-
Rossini, A.A.1
Like, A.A.2
Chick, W.L.3
Appel, M.C.4
Cahill, G.F.5
-
109
-
-
0038677068
-
Abnormal cardiac and skeletal muscle energy metabolism in patients with type 2 diabetes
-
Scheuermann-Freestone, M., Madsen, P. L., Manners, D., Blamire, A. M., Buckingham, R. E., Styles, P., et al. (2003). Abnormal cardiac and skeletal muscle energy metabolism in patients with type 2 diabetes. Circulation 107, 3040-3046. doi: 10.1161/01.CIR.0000072789.89096.10
-
(2003)
Circulation
, vol.107
, pp. 3040-3046
-
-
Scheuermann-Freestone, M.1
Madsen, P.L.2
Manners, D.3
Blamire, A.M.4
Buckingham, R.E.5
Styles, P.6
-
110
-
-
0028604486
-
STZ transport and cytotoxicity: Specific enhancement in GLUT2-expressing cells
-
Schnedl, W. J., Ferber, S., Johnson, J. H., and Newgard, C. B. (1994). STZ transport and cytotoxicity: specific enhancement in GLUT2-expressing cells. Diabetes 43, 1326-1333. doi: 10.2337/diab.43.11.1326
-
(1994)
Diabetes
, vol.43
, pp. 1326-1333
-
-
Schnedl, W.J.1
Ferber, S.2
Johnson, J.H.3
Newgard, C.B.4
-
111
-
-
84872051718
-
Acylcarnitines: Reflecting or inflicting insulin resistance?
-
Schooneman, M. G., Vaz, F. M., Houten, S. M., and Soeters, M. R. (2013). Acylcarnitines: reflecting or inflicting insulin resistance? Diabetes 62, 1-8. doi: 10.2337/db12-0466
-
(2013)
Diabetes
, vol.62
, pp. 1-8
-
-
Schooneman, M.G.1
Vaz, F.M.2
Houten, S.M.3
Soeters, M.R.4
-
112
-
-
68849099655
-
Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy
-
Schroeder, M. A., Atherton, H. J., Ball, D. R., Cole, M. A., Heather, L. C., Griffin, J. L., et al. (2009). Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy. FASEB J. 23, 2529-2538. doi: 10.1096/fj.09-129171
-
(2009)
FASEB J
, vol.23
, pp. 2529-2538
-
-
Schroeder, M.A.1
Atherton, H.J.2
Ball, D.R.3
Cole, M.A.4
Heather, L.C.5
Griffin, J.L.6
-
113
-
-
80052855442
-
Determining the in vivo regulation of cardiac pyruvate dehydrogenase based on label flux from hyperpolarised [1-13C]pyruvate
-
Schroeder, M. A., Atherton, H. J., Heather, L. C., Griffin, J. L., Clarke, K., Radda, G. K., et al. (2011). Determining the in vivo regulation of cardiac pyruvate dehydrogenase based on label flux from hyperpolarised [1-13C]pyruvate. NMR Biomed. 24, 980-987. doi: 10.1002/nbm.1668
-
(2011)
NMR Biomed
, vol.24
, pp. 980-987
-
-
Schroeder, M.A.1
Atherton, H.J.2
Heather, L.C.3
Griffin, J.L.4
Clarke, K.5
Radda, G.K.6
-
114
-
-
50149105620
-
In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance
-
Schroeder, M. A., Cochlin, L. E., Heather, L. C., Clarke, K., Radda, G. K., and Tyler, D. J. (2008). In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance. Proc. Natl. Acad. Sci. U.S.A. 105, 12051-12056. doi: 10.1073/pnas.0805953105
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 12051-12056
-
-
Schroeder, M.A.1
Cochlin, L.E.2
Heather, L.C.3
Clarke, K.4
Radda, G.K.5
Tyler, D.J.6
-
115
-
-
0028603590
-
Genetic and pathogenic basis of autoimmune diabetes in NOD mice
-
Serreze, D. V., and Leiter, E. H. (1994). Genetic and pathogenic basis of autoimmune diabetes in NOD mice. Curr. Opin. Immunol. 6, 900-906. doi: 10.1016/0952-7915(94)90011-6
-
(1994)
Curr. Opin. Immunol.
, vol.6
, pp. 900-906
-
-
Serreze, D.V.1
Leiter, E.H.2
-
116
-
-
84929103952
-
In vivo assessment of cardiac metabolism and function in the abdominal aortic banding model of compensated cardiac hypertrophy
-
Seymour, A.-M. L., Giles, L., Ball, V., Miller, J. J., Clarke, K., Carr, C. A., et al. (2015). In vivo assessment of cardiac metabolism and function in the abdominal aortic banding model of compensated cardiac hypertrophy. Cardiovasc. Res. 106, 249-260. doi: 10.1093/cvr/cvv101
-
(2015)
Cardiovasc. Res.
, vol.106
, pp. 249-260
-
-
Seymour, A.-M.L.1
Giles, L.2
Ball, V.3
Miller, J.J.4
Clarke, K.5
Carr, C.A.6
-
117
-
-
50349127453
-
Necrosis of islets of langerhans produced experimentally
-
Shaw Dunn, J., Sheehan, H. L., and Mcletchie, N. G. B. (1943). Necrosis of islets of langerhans produced experimentally. Lancet 241, 484-487. doi: 10.1016/s0140-6736(00)42072-6
-
(1943)
Lancet
, vol.241
, pp. 484-487
-
-
Shaw Dunn, J.1
Sheehan, H.L.2
Mcletchie, N.G.B.3
-
118
-
-
84934434996
-
Diabetes in zucker diabetic fatty rat
-
eds H.-G. Joost, H. Al-Hasani, and A. Schürmann Totowa, NJ: Humana Press
-
Shiota, M., and Printz, R. L. (2012). “Diabetes in zucker diabetic fatty rat,” in Animal Models in Diabetes Research Methods in Molecular Biology, eds H.-G. Joost, H. Al-Hasani, and A. Schürmann (Totowa, NJ: Humana Press), 103-123. doi: 10.1007/978-1-62703-068-7_8
-
(2012)
Animal Models in Diabetes Research Methods in Molecular Biology
, pp. 103-123
-
-
Shiota, M.1
Printz, R.L.2
-
119
-
-
48749113999
-
Time course of alterations in myocardial glucose utilization in the zucker diabetic fatty rat with correlation to gene expression of glucose transporters: A small-animal PET investigation
-
Shoghi, K. I., Gropler, R. J., Sharp, T., Herrero, P., Fettig, N., Su, Y., et al. (2008). Time course of alterations in myocardial glucose utilization in the zucker diabetic fatty rat with correlation to gene expression of glucose transporters: a small-animal PET investigation. J. Nucl. Med. 49, 1320-1327. doi: 10.2967/jnumed.108.051672
-
(2008)
J. Nucl. Med.
, vol.49
, pp. 1320-1327
-
-
Shoghi, K.I.1
Gropler, R.J.2
Sharp, T.3
Herrero, P.4
Fettig, N.5
Su, Y.6
-
120
-
-
0033399059
-
Altered creatine kinase enzyme kinetics in diabetic cardiomyopathy. A 31P NMR magnetization transfer study of the intact beating rat heart
-
Spindler, M., Saupe, K. W., Tian, R., Ahmed, S., Matlib, M. A., and Ingwall, J. S. (1999). Altered creatine kinase enzyme kinetics in diabetic cardiomyopathy. A 31P NMR magnetization transfer study of the intact beating rat heart. J. Mol. Cell. Cardiol. 31, 2175-2189. doi: 10.1006/jmcc.1999.1044
-
(1999)
J. Mol. Cell. Cardiol.
, vol.31
, pp. 2175-2189
-
-
Spindler, M.1
Saupe, K.W.2
Tian, R.3
Ahmed, S.4
Matlib, M.A.5
Ingwall, J.S.6
-
121
-
-
23844504364
-
Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: A model for type 2 diabetes and pharmacological screening
-
Srinivasan, K., Viswanad, B., Asrat, L., Kaul, C. L., and Ramarao, P. (2005). Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: a model for type 2 diabetes and pharmacological screening. Pharmacol. Res. 52, 313-320. doi: 10.1016/j.phrs.2005.05.004
-
(2005)
Pharmacol. Res.
, vol.52
, pp. 313-320
-
-
Srinivasan, K.1
Viswanad, B.2
Asrat, L.3
Kaul, C.L.4
Ramarao, P.5
-
122
-
-
21244492310
-
Myocardial substrate metabolism in the normal and failing heart
-
Stanley, W. C., Recchia, F. A., and Lopaschuk, G. D. (2005). Myocardial substrate metabolism in the normal and failing heart. Physiol. Rev. 85, 1093-1129. doi: 10.1152/physrev.00006.2004
-
(2005)
Physiol. Rev.
, vol.85
, pp. 1093-1129
-
-
Stanley, W.C.1
Recchia, F.A.2
Lopaschuk, G.D.3
-
123
-
-
16344395330
-
Accumulation of long-chain acylcarnitine and 3-hydroxy acylcarnitine molecular species in diabetic myocardium:? Identification of alterations in mitochondrial fatty acid processing in diabetic myocardium by shotgun lipidomics
-
Su, X., Han, X., Mancuso, D. J., Abendschein, D. R., and Gross, R. W. (2005). Accumulation of long-chain acylcarnitine and 3-hydroxy acylcarnitine molecular species in diabetic myocardium:? identification of alterations in mitochondrial fatty acid processing in diabetic myocardium by shotgun lipidomics. Biochemistry 44, 5234-5245. doi: 10.1021/bi047773a
-
(2005)
Biochemistry
, vol.44
, pp. 5234-5245
-
-
Su, X.1
Han, X.2
Mancuso, D.J.3
Abendschein, D.R.4
Gross, R.W.5
-
124
-
-
0024229140
-
Diet-induced type II diabetes in C57BL/6J mice
-
Surwit, R. S., Kuhn, C. M., Cochrane, C., McCubbin, J. A., and Feinglos, M. N. (1988). Diet-induced type II diabetes in C57BL/6J mice. Diabetes 37, 1163-1167. doi: 10.2337/diab.37.9.1163
-
(1988)
Diabetes
, vol.37
, pp. 1163-1167
-
-
Surwit, R.S.1
Kuhn, C.M.2
Cochrane, C.3
McCubbin, J.A.4
Feinglos, M.N.5
-
125
-
-
0028080510
-
Insulin resistance in chronic heart failure
-
Swan, J. W., Walton, C., Godsland, I. F., Clark, A. L., Coats, A. J. S., and Oliver, M. F. (1994). Insulin resistance in chronic heart failure. Eur. Heart J. 15, 1528-1532. doi: 10.1093/oxfordjournals.eurheartj.a060425
-
(1994)
Eur. Heart J.
, vol.15
, pp. 1528-1532
-
-
Swan, J.W.1
Walton, C.2
Godsland, I.F.3
Clark, A.L.4
Coats, A.J.S.5
Oliver, M.F.6
-
126
-
-
0037371754
-
Myocardial triglycerides and systolic function in humans: In vivo evaluation by localized proton spectroscopy and cardiac imaging
-
Szczepaniak, L. S., Dobbins, R. L., Metzger, G. J., Sartoni-D'Ambrosia, G., Arbique, D., Vongpatanasin, W., et al. (2003). Myocardial triglycerides and systolic function in humans: in vivo evaluation by localized proton spectroscopy and cardiac imaging. Magn. Reson. Med. 49, 417-423. doi: 10.1002/mrm.10372
-
(2003)
Magn. Reson. Med.
, vol.49
, pp. 417-423
-
-
Szczepaniak, L.S.1
Dobbins, R.L.2
Metzger, G.J.3
Sartoni-D'Ambrosia, G.4
Arbique, D.5
Vongpatanasin, W.6
-
127
-
-
85068267961
-
Novel “Dual Hit” rat model of diabetic cardiomyopathy
-
Thisted, L., Lindsay, R. T., Fosgerau, K., Secher, T., Thomsen, M. B., Jespersen, T., et al. (2018). Novel “Dual Hit” rat model of diabetic cardiomyopathy. Diabetes 67, 466-P. doi: 10.2337/db18-466-P
-
(2018)
Diabetes
, vol.67
, pp. 466
-
-
Thisted, L.1
Lindsay, R.T.2
Fosgerau, K.3
Secher, T.4
Thomsen, M.B.5
Jespersen, T.6
-
128
-
-
84938589054
-
In vivo targeted molecular magnetic resonance imaging of free radicals in diabetic cardiomyopathy within mice
-
Towner, R. A., Smith, N., Saunders, D., Carrizales, J., Lupu, F., Silasi-Mansat, R., et al. (2015). In vivo targeted molecular magnetic resonance imaging of free radicals in diabetic cardiomyopathy within mice. Free Radic. Res. 49, 1140-1146. doi: 10.3109/10715762.2015.1050587
-
(2015)
Free Radic. Res.
, vol.49
, pp. 1140-1146
-
-
Towner, R.A.1
Smith, N.2
Saunders, D.3
Carrizales, J.4
Lupu, F.5
Silasi-Mansat, R.6
-
129
-
-
0033694535
-
Lipotoxic diseases of nonadipose tissues in obesity
-
Unger, R., and Orci, L. (2000). Lipotoxic diseases of nonadipose tissues in obesity. Int. J. Obes. 24, S28-S32. doi: 10.1038/sj.ijo.0801498
-
(2000)
Int. J. Obes.
, vol.24
, pp. S28-S32
-
-
Unger, R.1
Orci, L.2
-
130
-
-
84880923169
-
Moderate dietary weight loss reduces myocardial steatosis in obese and overweight women
-
Utz, W., Engeli, S., Haufe, S., Kast, P., Böhnke, J., Haas, V., et al. (2013). Moderate dietary weight loss reduces myocardial steatosis in obese and overweight women. Int. J. Cardiol. 167, 905-909. doi: 10.1016/j.ijcard.2012.03.104
-
(2013)
Int. J. Cardiol.
, vol.167
, pp. 905-909
-
-
Utz, W.1
Engeli, S.2
Haufe, S.3
Kast, P.4
Böhnke, J.5
Haas, V.6
-
131
-
-
68949215755
-
Altered myocardial substrate metabolism is associated with myocardial dysfunction in early diabetic cardiomyopathy in rats: Studies using positron emission tomography
-
van den Brom, C. E., Huisman, M. C., Vlasblom, R., Boontje, N. M., Duijst, S., Lubberink, M., et al. (2009). Altered myocardial substrate metabolism is associated with myocardial dysfunction in early diabetic cardiomyopathy in rats: studies using positron emission tomography. Cardiovasc. Diabetol. 8:39. doi: 10.1186/1475-2840-8-39
-
(2009)
Cardiovasc. Diabetol.
, vol.8
, pp. 39
-
-
Van Den Brom, C.E.1
Huisman, M.C.2
Vlasblom, R.3
Boontje, N.M.4
Duijst, S.5
Lubberink, M.6
-
132
-
-
65449182043
-
Pioglitazone improves cardiac function and alters myocardial substrate metabolism without affecting cardiac triglyceride accumulation and high-energy phosphate metabolism in patients with well-controlled type 2 diabetes mellitus
-
van der Meer, R. W., Rijzewijk, L. J., de Jong, H. W. A. M., Lamb, H. J., Lubberink, M., Romijn, J. A., et al. (2009). Pioglitazone improves cardiac function and alters myocardial substrate metabolism without affecting cardiac triglyceride accumulation and high-energy phosphate metabolism in patients with well-controlled type 2 diabetes mellitus. Circulation 119, 2069-2077. doi: 10.1161/CIRCULATIONAHA.108.803916
-
(2009)
Circulation
, vol.119
, pp. 2069-2077
-
-
Van Der Meer, R.W.1
Rijzewijk, L.J.2
De Jong, H.W.A.M.3
Lamb, H.J.4
Lubberink, M.5
Romijn, J.A.6
-
133
-
-
84948129560
-
Mitochondrial complex I defect and increased fatty acid oxidation enhance protein lysine acetylation in the diabetic heart
-
Vazquez, E. J., Berthiaume, J. M., Kamath, V., Achike, O., Buchanan, E., Montano, M. M., et al. (2015). Mitochondrial complex I defect and increased fatty acid oxidation enhance protein lysine acetylation in the diabetic heart. Cardiovasc. Res. 107, 453-465. doi: 10.1093/cvr/cvv183
-
(2015)
Cardiovasc. Res.
, vol.107
, pp. 453-465
-
-
Vazquez, E.J.1
Berthiaume, J.M.2
Kamath, V.3
Achike, O.4
Buchanan, E.5
Montano, M.M.6
-
134
-
-
80052800016
-
The creatine kinase system and pleiotropic effects of creatine
-
Wallimann, T., Tokarska-Schlattner, M., and Schlattner, U. (2011). The creatine kinase system and pleiotropic effects of creatine. Amino Acids 40, 1271-1296. doi: 10.1007/s00726-011-0877-3
-
(2011)
Amino Acids
, vol.40
, pp. 1271-1296
-
-
Wallimann, T.1
Tokarska-Schlattner, M.2
Schlattner, U.3
-
135
-
-
84925228644
-
Leptin- And leptin receptor-deficient rodent models: Relevance for human type 2 diabetes
-
Wang, B., Chandrasekera, P. C., and Pippin, J. J. (2014). Leptin- and leptin receptor-deficient rodent models: relevance for human type 2 diabetes. Curr. Diabetes Rev. 10, 131-145. doi: 10.2174/1573399810666140508121012
-
(2014)
Curr. Diabetes Rev.
, vol.10
, pp. 131-145
-
-
Wang, B.1
Chandrasekera, P.C.2
Pippin, J.J.3
-
136
-
-
0032918044
-
A mutation in the insulin 2 gene induces diabetes with severe pancreatic β-cell dysfunction in the Mody mouse
-
Wang, J., Takeuchi, T., Tanaka, S., Kubo, S.-K., Kayo, T., Lu, D., et al. (1999). A mutation in the insulin 2 gene induces diabetes with severe pancreatic β-cell dysfunction in the Mody mouse. J. Clin. Invest. 103, 27-37. doi: 10.1172/JCI4431
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 27-37
-
-
Wang, J.1
Takeuchi, T.2
Tanaka, S.3
Kubo, S.-K.4
Kayo, T.5
Lu, D.6
-
137
-
-
18044389144
-
Impact of altered substrate utilization on cardiac function in isolated hearts from Zucker diabetic fatty rats
-
Wang, P., Lloyd, S. G., Zeng, H., Bonen, A., and Chatham, J. C. (2005). Impact of altered substrate utilization on cardiac function in isolated hearts from Zucker diabetic fatty rats. Am. J. Physiol. Heart Circ. Physiol. 288, H2102-H2110. doi: 10.1152/ajpheart.00935.2004
-
(2005)
Am. J. Physiol. Heart Circ. Physiol.
, vol.288
, pp. H2102-H2110
-
-
Wang, P.1
Lloyd, S.G.2
Zeng, H.3
Bonen, A.4
Chatham, J.C.5
-
138
-
-
84947262080
-
Comprehensive metabolic profiling of age-related mitochondrial dysfunction in the high-fat-fed ob/ob mouse heart
-
Wang, X., West, J. A., Murray, A. J., and Griffin, J. L. (2015). Comprehensive metabolic profiling of age-related mitochondrial dysfunction in the high-fat-fed ob/ob mouse heart. J. Proteome Res. 14, 2849-2862. doi: 10.1021/acs.jproteome.5b00128
-
(2015)
J. Proteome Res.
, vol.14
, pp. 2849-2862
-
-
Wang, X.1
West, J.A.2
Murray, A.J.3
Griffin, J.L.4
-
139
-
-
33745070330
-
Assessment of myocardial metabolism in diabetic rats using small-animal PET: A feasibility study
-
Welch, M. J., Lewis, J. S., Kim, J., Sharp, T. L., Dence, C. S., Gropler, R. J., et al. (2006). Assessment of myocardial metabolism in diabetic rats using small-animal PET: a feasibility study. J. Nucl. Med. 47, 689-697.
-
(2006)
J. Nucl. Med.
, vol.47
, pp. 689-697
-
-
Welch, M.J.1
Lewis, J.S.2
Kim, J.3
Sharp, T.L.4
Dence, C.S.5
Gropler, R.J.6
-
140
-
-
0023240892
-
Genetic control of diabetes and insulitis in the nonobese diabetic (n.d.) mouse
-
Wicker, L. S., Miller, B. J., Coker, L. Z., McNally, S. E., Scott, S., Mullen, Y., et al. (1987). Genetic control of diabetes and insulitis in the nonobese diabetic (n.d.) mouse. J. Exp. Med. 165, 1639-1654. doi: 10.1084/jem.165.6.1639
-
(1987)
J. Exp. Med.
, vol.165
, pp. 1639-1654
-
-
Wicker, L.S.1
Miller, B.J.2
Coker, L.Z.3
McNally, S.E.4
Scott, S.5
Mullen, Y.6
-
141
-
-
33846088138
-
HMDB: The human metabolome database
-
Wishart, D. S., Tzur, D., Knox, C., Eisner, R., Guo, A. C., Young, N., et al. (2007). HMDB: the human metabolome database. Nucleic Acids Res. 35, D521-D526. doi: 10.1093/nar/gkl923
-
(2007)
Nucleic Acids Res
, vol.35
, pp. D521-D526
-
-
Wishart, D.S.1
Tzur, D.2
Knox, C.3
Eisner, R.4
Guo, A.C.5
Young, N.6
-
142
-
-
84990821378
-
Animal models of metabolic syndrome: A review
-
Wong, S. K., Chin, K.-Y., Suhaimi, F. H., Fairus, A., and Ima-Nirwana, S. (2016). Animal models of metabolic syndrome: a review. Nutr. Metab. 13:65.
-
(2016)
Nutr. Metab.
, vol.13
, pp. 65
-
-
Wong, S.K.1
Chin, K.-Y.2
Suhaimi, F.H.3
Fairus, A.4
Ima-Nirwana, S.5
-
143
-
-
84936942895
-
Streptozotocin-induced type 1 diabetes in rodents as a model for studying mitochondrial mechanisms of diabetic β cell glucotoxicity
-
Wu, J., and Yan, L.-J. (2015). Streptozotocin-induced type 1 diabetes in rodents as a model for studying mitochondrial mechanisms of diabetic β cell glucotoxicity. Diabetes Metab. Syndr. Obes. 8, 181-188. doi: 10.2147/DMSO.S82272
-
(2015)
Diabetes Metab. Syndr. Obes.
, vol.8
, pp. 181-188
-
-
Wu, J.1
Yan, L.-J.2
-
144
-
-
0030907296
-
A novel locus, Mody4, distal to D7Mit189 o chromosome 7 determines early-onset NIDDM in nonobese C57BL/6 (Akita) mutant mice
-
Yoshioka, M., Kayo, T., Ikeda, T., and Koizuni, A. (1997). A novel locus, Mody4, distal to D7Mit189 o chromosome 7 determines early-onset NIDDM in nonobese C57BL/6 (Akita) mutant mice. Diabetes 46, 887-894. doi: 10.2337/diab.46.5.887
-
(1997)
Diabetes
, vol.46
, pp. 887-894
-
-
Yoshioka, M.1
Kayo, T.2
Ikeda, T.3
Koizuni, A.4
-
145
-
-
84874672555
-
Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload
-
Zhabyeyev, P., Gandhi, M., Mori, J., Basu, R., Kassiri, Z., Clanachan, A., et al. (2013). Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload. Cardiovasc. Res. 97, 676-685. doi: 10.1093/cvr/cvs424
-
(2013)
Cardiovasc. Res.
, vol.97
, pp. 676-685
-
-
Zhabyeyev, P.1
Gandhi, M.2
Mori, J.3
Basu, R.4
Kassiri, Z.5
Clanachan, A.6
-
146
-
-
78650481257
-
Cardiac diacylglycerol accumulation in high fat-fed mice is associated with impaired insulin-stimulated glucose oxidation
-
Zhang, L., Ussher, J. R., Oka, T., Cadete, V. J. J., Wagg, C., and Lopaschuk, G. D. (2011). Cardiac diacylglycerol accumulation in high fat-fed mice is associated with impaired insulin-stimulated glucose oxidation. Cardiovasc. Res. 89, 148-156. doi: 10.1093/cvr/cvq266
-
(2011)
Cardiovasc. Res.
, vol.89
, pp. 148-156
-
-
Zhang, L.1
Ussher, J.R.2
Oka, T.3
Cadete, V.J.J.4
Wagg, C.5
Lopaschuk, G.D.6
-
147
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., and Friedman, J. M. (1994). Positional cloning of the mouse obese gene and its human homologue. Nature 372, 425-432. doi: 10.1038/372425a0
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
148
-
-
85052467314
-
Identification of energy metabolism changes in diabetic cardiomyopathy rats using a metabonomic approach
-
Zhao, L., Dong, M., Xu, C., Zheng, H., Wei, T., Liu, K., et al. (2018). Identification of energy metabolism changes in diabetic cardiomyopathy rats using a metabonomic approach. Cell. Physiol. Biochem. 48, 934-946. doi: 10.1159/000491960
-
(2018)
Cell. Physiol. Biochem.
, vol.48
, pp. 934-946
-
-
Zhao, L.1
Dong, M.2
Xu, C.3
Zheng, H.4
Wei, T.5
Liu, K.6
-
149
-
-
0015336896
-
Insulin and obesity in the zucker genetically obese rat “Fatty
-
Zucker, L. M., and Antoniades, H. N. (1972). Insulin and obesity in the zucker genetically obese rat “Fatty.”. Endocrinology 90, 1320-1330. doi: 10.1210/endo-90-5-1320
-
(1972)
Endocrinology
, vol.90
, pp. 1320-1330
-
-
Zucker, L.M.1
Antoniades, H.N.2
-
150
-
-
77957216320
-
Fatty, a new mutation in the rat
-
Zucker, L. M., and Zucker, T. F. (1961). Fatty, a new mutation in the rat. J. Hered. 52, 275-278. doi: 10.1093/oxfordjournals.jhered.a107093
-
(1961)
J. Hered.
, vol.52
, pp. 275-278
-
-
Zucker, L.M.1
Zucker, T.F.2
-
151
-
-
84880343712
-
Preparative gas chromatography and its applications
-
Zuo, H.-L., Yang, F.-Q., Huang, W.-H., and Xia, Z.-N. (2013). Preparative gas chromatography and its applications. J. Chromatogr. Sci. 51, 704-715. doi: 10.1093/chromsci/bmt040
-
(2013)
J. Chromatogr. Sci.
, vol.51
, pp. 704-715
-
-
Zuo, H.-L.1
Yang, F.-Q.2
Huang, W.-H.3
Xia, Z.-N.4
|