Accumulation of long-chain acylcarnitine and 3-hydroxy acylcarnitine molecular species in diabetic myocardium: Identification of alterations in mitochondrial fatty acid processing in diabetic myocardium by shotgun lipidomics

Biochemistry

Volumn 44, Issue 13, 2005, Pages 5234-5245

  Su, Xiong ^a   Han, Xianlin ^a   Mancuso, David J ^a   Abendschein, Dana R ^a   Gross, Richard W ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; ENZYMES; INSULIN; LIPIDS; MASS SPECTROMETRY; METABOLISM; RNA;

DIABETIC CARDIOMYOPATHY; LIPID METABOLISM; MOLECULAR SPECIES; TANDEM MASS SPECTROMETRY;

BIOCHEMISTRY;

3 HYDROXYACYLCARNITINE; ACYLCARNITINE; CALCIUM INDEPENDENT PHOSPHOLIPASE A2; FATTY ACID; INSULIN; MESSENGER RNA; PHOSPHOLIPASE A2; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOMYOPATHY; CONTROLLED STUDY; DIABETES MELLITUS; ENERGY; ENERGY YIELD; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INACTIVATION; FATTY ACID ANALYSIS; FATTY ACID SYNTHESIS; HEART MITOCHONDRION; HEART MUSCLE; HOMEOSTASIS; HYDROXYLATION; LIPID METABOLISM; LIPID STORAGE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SHOTGUN LIPIDOMICS; TANDEM MASS SPECTROMETRY; TRANSGENIC ANIMAL;

ANIMALS; BASE SEQUENCE; CARDIOMYOPATHIES; CARNITINE; CRICETINAE; DIABETES MELLITUS, EXPERIMENTAL; DNA; HYDROXYLATION; INSULIN; MALE; MICE; MICE, TRANSGENIC; MYOCARDIAL ISCHEMIA; MYOCARDIUM; PHOSPHOLIPASES A; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 16344395330     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi047773a     Document Type: Article

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