Dietary nitrate increases arginine availability and protects mitochondrial complex I and energetics in the hypoxic rat heart

Journal of Physiology

Volumn 592, Issue 21, 2014, Pages 4715-4731

  Ashmore, Tom ^a   Fernandez, Bernadette O ^b   Branco Price, Cristina ^a   West, James A ^a,c   Cowburn, Andrew S ^a   Heather, Lisa C ^d   Griffin, Julian L ^a,c   Johnson, Randall S ^a   Feelisch, Martin ^b   Murray, Andrew J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^c MRC HUMAN NUTRITION RESEARCH   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ARGINASE; ARGININE; NITRATE; OXYGEN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SODIUM CHLORIDE; SODIUM NITRATE; HYPOXIA INDUCIBLE FACTOR 1; NITRIC ACID DERIVATIVE; NITRITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOAVAILABILITY; BIOENERGY; BLOOD FLOW; BREATHING RATE; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENZYME ACTIVITY; HEART INJURY; HEART MUSCLE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; METABOLIC DISORDER; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PROTEIN CARBONYLATION; PROTEIN EXPRESSION; RAT; RESPIRATORY CHAIN; TISSUE OXYGENATION; WISTAR RAT; ANIMAL; CHEMISTRY; DIET; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HEART; MALE; METABOLISM; PHYSIOLOGY;

ANIMALS; ARGINASE; ARGININE; DIET; ELECTRON TRANSPORT COMPLEX I; GENE EXPRESSION REGULATION; HEART; HYPOXIA-INDUCIBLE FACTOR 1; MALE; MYOCARDIUM; NITRATES; NITRITES; OXIDATIVE STRESS; OXYGEN; RATS; RATS, WISTAR;

EID: 84921732687     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2014.275263     Document Type: Article

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