Altered creatine kinase enzyme kinetics in diabetic cardiomyopathy. A 31P NMR magnetization transfer study of the intact beating rat heart

Journal of Molecular and Cellular Cardiology

Volumn 31, Issue 12, 1999, Pages 2175-2189

  Spindler, Matthias ^a   Saupe, Kurt W ^a   Tian, Rong ^a   Ahmed, Saadia ^b   Matlib, Mohammed A ^b   Ingwall, Joanne S ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

31P NMR; ATP; Creatine; Creatine kinase; Creatine kinase reaction velocity; Diabetes mellitus; Heart failure

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM; CREATINE; CREATINE KINASE; ISOENZYME;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOMYOPATHY; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME ACTIVITY; ENZYME KINETICS; HEART BEAT; HEART MUSCLE CONTRACTILITY; HEART MUSCLE PERFUSION; HEART STIMULATION; HEART WORK; HIGH ENERGY PHOSPHATE; MALE; NONHUMAN; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0033399059     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1999.1044     Document Type: Article

References (54)

1. Allison TB, Bruttig SP, Crass MF, Eliot RS, Shipp JC. Reduced high-energy phosphate levels in rat hearts. I. Effect of alloxan diabetes. Am J Physiol. 230:1976;1744-1750.
2. Awaji Y, Hashimoto H, Matsui Y, Kawaguchi K, Okumura K, Ito T, Satake T. Isoenzyme profiles of creatine kinase, lactate dehydrogenase, and aspartate aminotransferase in the diabetic heart: comparison with hereditary and catecholamine cardiomyopathies. Cardiovasc Res. 24:1990;547-554.
3. Bak MI, Ingwall JS. NMR-invisible ATP in heart: fact or fiction? Am J Physiol. 262 (Endocrinol Metab 25):1992;E943-E947.
4. Bielefeld DR, Pace CS, Boshell BR. Altered sensitivity of chronic diabetic rat heart to calcium. Am J Physiol. 245:1983;E560-E567.
5. 31P NMR surface coil studies in living rat. Circ Res. 26:1987;6083-6090.
6. 31P NMR magnetization transfer study. J Biol Chem. 260:1985;3512-3517.
7. Brooks WW, Healey NA, Sen S, Conrad CH, Bing OHL. Oxygen cost of stress development in hypertrophied and failing hearts from the spontaneously hypertensive rat. Hypertension. 2:1993;56-64.
8. 13C-NMR study of glucose oxidation in the intact functioning rat heart following diabetes-induced cardiomyopathy. J Mol Cell Cardiol. 25:1993;1203-1213.
9. Chatham JC, Forder JR. Relationship between cardiac function and substrate oxidation in hearts of diabetic rats. Am J Physiol. 273 (Heart Circ Physiol 42):1997;H52-H58.
10. Davidoff AJ, Pinault FM, Rodgers RL. Ventricular relaxation of diabetic spontaneously hypertensive rat. Hypertension. 15:1990;643-651.
11. Dhalla NS, Golfman LS, Elimban V, Takeda N. Remodelling of subcellular organelles during the development of diabetic cardiomyopathy. In: Chatham JC, Forder JR, McNeill JH, eds. The Heart in Diabetes. Kluwer Academic Publishers. 1996;100-142.
12. Fein FS, Kornstein LB, Strobeck JE, Caspasso JM, Sonnenblick EH. Altered myocardial mechanics in diabetic rats. Circ Res. 47:1980;922-933.
13. Fein FS, Sonnenblick EH. Diabetic cardiomyopathy. Cardiovasc Drug Therap. 8:1994;65-73.
14. Flarsheim CE, Grupp IL, Matlib MA. Mitochondrial dysfunction accompanies diastolic dysfunction in diabetic cardiomyopathy. Am J Physiol. 271:1996;H192-H202.
15. Forsen S, Hoffmann RA. Study of moderately rapid chemical exchange reactions by means of nuclear magnetic double resonance. J Chem Phys. 39:1963;2892-2901.
16. 1measurements with and without exchange in the heart. Magn Reson Med. 30:1993;45-50.
17. 4in diabetes. Diabetes. 30:1981;694-699.
18. Hoit BD, Castro C, Bultron G, Knight S, Matlib MA. Non-invasive evaluation of cardiac dysfunction by echocardiography in streptozotocin-induced diabetic rat. J. Cardiac Failure. 5: in press:1999.
19. Ingebretsen CG, Moreau P, Hawelu-Johnson C, Ingebretsen WR. Performance of diabetic rat hearts: effect of anoxia and increased work. Am J Physiol (Heart Circ Physiol 8). 239:1980;H614-H620.
20. Ingwall JS, Kramer MF, Fifer MA, Lorell BH, Shemin R, Grossman W, Allen PD. The creatine kinase system in normal and diseased myocardium. N Engl J Med. 313:1985;1050-1054.
21. 31P magnetization transfer studies. In: Smirnoff VN, Katz A, eds. Proc 6th Joint USA-USSR Symposium on Myocardial Metabolism. New York, NY: Gordon and Brach. 1987;3-48.
22. Ingwall JS. Is cardiac failure a consequence of decreased energy reserve? Circulation. 87 (Suppl. VII):1993;VII58-VII62.
23. Kammermeier H. Microassay of free and total creatine from tissue extracts by combination of chromatographic and fluorometric methods. Anal Biochem. 56:1973;341-345.
24. Kannel WB, Hjortland M, Castelli WP. Role of diabetes in congestive heart failure: The Framingham Study. Am J Cardiol. 34:1974;29-34.
25. eqof the creatine kinase reaction and other phosphate hydrolyses and phosphate transfer reactions. J Biol Chem. 254:1979;6528-6537.
26. Liao R, Nascimben L, Friedrich J, Gwathmey JK, Ingwall JS. Decreased energy reserve in an animal model of dilated cardiomyopathy: Relationship to contractile performance. Circ Res. 78:1996;893-902.
27. Litwin SE, Raya TE, Anderson PG, Daugherty S, Goldman S. Abnormal cardiac function in the streptozotocin-diabetic rat. J Clin Invest. 86:1990;481-488.
28. Lopaschuk GD, Spafford M. Response of isolated working hearts to fatty acids and carnitine palmitoyltransferase I inhibition during reduction of coronary flow in acutely and chronically diabetic rats. Circ Res. 65:1989;378-387.
29. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem. 193:1951;265-275.
30. Matsumoto Y, Kaneko M, Kobayashi A, Fujise Y, Yamazaki N. Creatine kinase kinetics in diabetic cardiomyopathy. Am J Physiol (Endocrinol Metab 31). 268:1995;E1070-E1076.
31. McAuliffe JJ, Perry SB, Brooks EE, Ingwall JS. Kinetics of the creatine kinase reaction in neonatal rabbit heart. Biochemistry. 30:1991;2585-2593.
32. Mokhtar N, Rousseau-Migneron S, Tancrede G, Nadeau A. Physical training attenuates phosphocreatine and long-chain acyl-CoA alterations in diabetic rat heart. J Appl Physiol. 74(4):1993;1785-1790.
33. Morrison JF, Cleland WW. Isotope exchange studies of the mechanism of the reaction catalyzed by adenosin triphosphate: creatine phosphotransferase. J Biol Chem. 241:1966;673-683.
34. Nascimben L, Friedrich J, Liao R, Pauletto P, Pessina AC, Ingwall JS. Enalapril treatment increases cardiac performance and energy reserve via creatine kinase reaction in myocardium of Syrian myopathic hamster with advanced heart failure. Circulation. 91:1995;1824-1833.
35. Neubauer S, Horn M, Naumann A, Tian R, Hu K, Laser M, Friedrich J, Gaudron P, Schnackerz K, Ingwall JS, Ertl G. Impairment of energy metabolism in intact residual myocardium of rat hearts with chronic myocardial infarction. J Clin Invest. 95:1995;1092-1100.
36. cprat heart. J Mol Cell Cardiol. 30:1998;235-241.
37. Penpargkul S, Schaible T, Yipintsol T, Scheuer J. The effect of diabetes on performance and metabolism of rat hearts. Circ Res. 47:1980;911-921.
38. 31P nuclear-magnetic-resonance study. Biochem J. 210:1983;477-481.
39. Pieper GM, Salhany JM, Murray WJ, Shao TW, Eliot RS. Lipid-mediated impairment of normal energy metabolism in the isolated perfused diabetic rat heart studied by phosphorus-31 NMR and chemical extraction. BBA. 803:1984;229-240.
40. Ponticos M, Lu QL, Morgan JE, Hardie DG, Partridge TA, Carling D. Dual regulation of the AMP-activated protein kinase provides a novel mechanism for the control of creatine kinase in skeletal muscle. EMBO J. 17(6):1998;1688-1699.
41. Popovich BK, Boeheler KR, Dillmann WH. Diabetes decreased creatine kinase enzyme activity and mRNA levels in the rat heart. Am J Physiol (Endocrinol Metab 20). 257:1989;E573-E577.
42. Popovich BK, Sayen MR, Dillmann WH. Insulin responsiveness of CK-M and CK-B mRNA in the diabetic rat heart. Am J Physiol (Endocrinol Metab 24). 261:1991;E377-E381.
43. Regan TJ, Lyons MM, Ahmed SS, Levinson GE, Oldewurtel HA, Ahmed MR, Haider B. Evidence for cardiomyopathy in familial diabetes mellitus. J Clin Invest. 60:1977;885-899.
44. Rao V, Vadlamudi SV, Rogers RL, McNeill JH. The effect of chronic alloxan- and streptozotocin-induced diabetes on isolated rat heart performance. Can J Pharmacol. 60:1982;902-911.
45. Rosalski SB. An improved procedure for serum creatine phosphokinase determination. J Lab Clin Med. 69:1967;696-705.
46. Rubler S, Dlugash J, Yuceoglu YZ, Kumral T, Branwood AW, Grishman A. New type of cardiomyopathy associated with diabetic glomerulosclerosis. Am J Cardiol. 30:1972;595-602.
47. Savabi F, Kirsch A. Alteration of the phosphocreatine energy shuttle components in diabetic rat hearts. J Mol Cell Cardiol. 23:1991;1323-1333.
48. Savabi F. Mitochondrial creatine phosphokinase deficiency in diabetic rat heart. Biochem Biophys Res Commun. 154:1988;469-475.
49. Savarese JJ, Berkowitz BA. β -adrenergic receptor decrease in diabetic rat hearts. Life Sci. 25:1979;2075-2078.
50. Seppet EK, Saks VA. Thyroid hormones and the creatine kinase system in cardiac cells. Mol Cell Biochem. 133/134:1994;299-309.
51. Smith SH, Kramer MF, Reis I, Bishop SP, Ingwall JS. Regional changes in creatine kinase and myocyte size in hypertensive and nonhypertensive cardiac hypertrophy. Circ Res. 67:1990;1334-1344.
52. Stroedter D, Schmidt T, Bretzel RG, Federlin K. Glucose metabolism and left ventricular dysfunction are normalized by insulin and islet transplantation in mild diabetes in the rat. Acta Diabetol. 32:1995;235-243.
53. Uusitupa MIJ, Mustonen JN, Airaksinen KEJ. Diabetic heart muscle disease. Ann Med. 22:1990;377-386.
54. Veech RL, Lawson JWR, Cornell NW, Krebs HA. Cytosolic phosphorylation potential. J Biol Chem. 254:1979;6538-6547.