Comprehensive Metabolic Profiling of Age-Related Mitochondrial Dysfunction in the High-Fat-Fed ob/ob Mouse Heart

Journal of Proteome Research

Volumn 14, Issue 7, 2015, Pages 2849-2862

  Wang, Xinzhu ^a,b   West, James A ^a,b   Murray, Andrew J ^c   Griffin, Julian L ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b MEDICAL RESEARCH COUNCIL   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

aging; high fat diet; metabolomics; obesity; Respiratory capacity

Indexed keywords

8 HYDROXYGUANINE; ACYLCARNITINE; CITRATE SYNTHASE; DIACYLGLYCEROL; GLUCOSE; GLUTATHIONE; GLUTATHIONE DISULFIDE; HEMOGLOBIN A1C; INSULIN; LIPID; TRIACYLGLYCEROL; BIOLOGICAL MARKER;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FAT INTAKE; FATTY ACID OXIDATION; HEART MUSCLE; LIPID DIET; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; METABOLOMICS; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OBESITY; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PRIORITY JOURNAL; ANIMAL; HEART MITOCHONDRION; METABOLISM; PHYSIOLOGY;

AGING; ANIMALS; BIOMARKERS; DIET, HIGH-FAT; MALE; MICE; MITOCHONDRIA, HEART; OXIDATIVE STRESS;

EID: 84947262080     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/acs.jproteome.5b00128     Document Type: Article

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