Cardiac diastolic dysfunction in high-fat diet fed mice is associated with lipotoxicity without impairment of cardiac energetics in vivo

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1841, Issue 10, 2014, Pages 1525-1537

  Abdurrachim, Desiree ^a   Ciapaite, Jolita ^a,b   Wessels, Bart ^a   Nabben, Miranda ^a   Luiken, Joost J F P ^c   Nicolay, Klaas ^a   Prompers, Jeanine J ^a  

^a EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

^c MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Calcium homeostasis; Cardiac energetics; Cardiomyopathy; Diet induced obesity; Lipotoxicity

Indexed keywords

CASPASE 3; CASPASE 9; CITRATE SYNTHASE; FATTY ACID; MITOCHONDRIAL PROTEIN; PHOSPHORUS 31; PROCASPASE 3; PROCASPASE 9; REACTIVE OXYGEN METABOLITE; TRIACYLGLYCEROL; TROPONIN T;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CALCIUM HOMEOSTASIS; CARDIOMYOPATHY; CONTROLLED STUDY; DIASTOLIC DYSFUNCTION; ENDOPLASMIC RETICULUM; ENERGY METABOLISM; ENZYME ACTIVITY; GLUCOSE ASSAY; GLUCOSE BLOOD LEVEL; GLUCOSE OXIDATION; HEART LEFT VENTRICLE MASS; HEART MITOCHONDRION; HEART MUSCLE FIBROSIS; INSULIN BLOOD LEVEL; LIPID DIET; LIPID STORAGE; LIPOTOXICITY; MALE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OBESITY; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 84910067714     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2014.07.016     Document Type: Article

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