Triptolide improves systolic function and myocardial energy metabolism of diabetic cardiomyopathy in streptozotocin-induced diabetic rats

BMC Cardiovascular Disorders

Volumn 15, Issue 1, 2015, Pages

  Liang, Zhongshu ^a   Leo, Sunnar ^a   Wen, Helin ^a   Ouyang, Mao ^a   Jiang, Weihong ^a   Yang, Kan ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

31P NMR spectroscopy; Cardiac energy metabolism; Diabetic cardiomyopathy; MAPK; Triptolide

Indexed keywords

ADENOSINE TRIPHOSPHATE; CREATINE PHOSPHATE; MITOGEN ACTIVATED PROTEIN KINASE P38; TRIPTOLIDE; DITERPENE; EPOXIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PHENANTHRENE DERIVATIVE; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIAC MASS INDEX; CARDIOVASCULAR EFFECT; CARDIOVASCULAR PARAMETERS; CONTROLLED STUDY; DIABETIC CARDIOMYOPATHY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG MECHANISM; ECHOCARDIOGRAPHY; ENERGY METABOLISM; HEART EJECTION FRACTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE ENDSYSTOLIC VOLUME; HEART MUSCLE METABOLISM; HEART PERFUSION; HEART SIZE; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REAL TIME ULTRASOUND SCANNER; SIGNAL TRANSDUCTION; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; TISSUE PREPARATION; TREATMENT DURATION; UPREGULATION; WESTERN BLOTTING; ANIMAL; CARDIAC MUSCLE; DIABETIC CARDIOMYOPATHIES; DIAGNOSTIC IMAGING; DRUG EFFECTS; ECHOGRAPHY; EXPERIMENTAL DIABETES MELLITUS; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT; SYSTOLE;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC CARDIOMYOPATHIES; DITERPENES; ENERGY METABOLISM; EPOXY COMPOUNDS; MAGNETIC RESONANCE SPECTROSCOPY; MYOCARDIUM; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHENANTHRENES; RATS, SPRAGUE-DAWLEY; STREPTOZOCIN; SYSTOLE; ULTRASONOGRAPHY;

EID: 84929094858     PISSN: None     EISSN: 14712261     Source Type: Journal    
DOI: 10.1186/s12872-015-0030-4     Document Type: Article

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