Relationship between left ventricular structural and metabolic remodeling in type 2 diabetes

Diabetes

Volumn 65, Issue 1, 2016, Pages 44-52

  Levelt, Eylem ^a   Mahmod, Masliza ^a   Piechnik, Stefan K ^a   Ariga, Rina ^a   Francis, Jane M ^a   Rodgers, Christopher T ^a   Clarke, William T ^a   Sabharwal, Nikant ^b   Schneider, Jurgen E ^a   Karamitsos, Theodoros D ^a,c   Clarke, Kieran ^a   Rider, Oliver J ^a   Neubauer, Stefan ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^c ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ADENOSINE TRIPHOSPHATE; ALBUMIN; CREATINE PHOSPHATE; CREATININE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FATTY ACID; GADOLINIUM; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IODINATED CONTRAST MEDIUM; LOW DENSITY LIPOPROTEIN CHOLESTEROL; METFORMIN; SULFONYLUREA; TRIACYLGLYCEROL; PHOSPHORUS;

ADULT; ARTICLE; BLOOD PRESSURE; BODY MASS; CARDIAC STEATOSIS; CARDIOVASCULAR MAGNETIC RESONANCE; CLINICAL ARTICLE; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; COMPUTED TOMOGRAPHY SCANNER; CONTROLLED STUDY; DIABETIC PATIENT; DISEASE ASSOCIATION; ECHOCARDIOGRAPH; ENERGY TRANSFER; EXTRACELLULAR SPACE; FEMALE; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE MASS; HEART MUSCLE CONTRACTILITY; HEART MUSCLE METABOLISM; HEART VENTRICLE REMODELING; HUMAN; LEFT VENTRICULAR SYSTOLIC DYSFUNCTION; MALE; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STEATOSIS; TISSUE CHARACTERIZATION; TRANSTHORACIC ECHOCARDIOGRAPHY; ULTRASOUND TRANSDUCER; ADIPOSE TISSUE; CARDIAC MUSCLE; CASE CONTROL STUDY; CINE MAGNETIC RESONANCE IMAGING; COMPLICATION; CORONARY ANGIOGRAPHY; ECHOCARDIOGRAPHY; HEART; HEART LEFT VENTRICLE HYPERTROPHY; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOLOGY; PATHOPHYSIOLOGY; SYSTOLE; X-RAY COMPUTED TOMOGRAPHY;

ADENOSINE TRIPHOSPHATE; ADIPOSE TISSUE; ADULT; CASE-CONTROL STUDIES; CORONARY ANGIOGRAPHY; DIABETES MELLITUS, TYPE 2; ECHOCARDIOGRAPHY; FEMALE; HEART; HUMANS; HYPERTROPHY, LEFT VENTRICULAR; MAGNETIC RESONANCE IMAGING, CINE; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MIDDLE AGED; MYOCARDIUM; PHOSPHOCREATINE; PHOSPHORUS ISOTOPES; PROTON MAGNETIC RESONANCE SPECTROSCOPY; SYSTOLE; TOMOGRAPHY, X-RAY COMPUTED; TRIGLYCERIDES; VENTRICULAR REMODELING;

EID: 84962173633     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db15-0627     Document Type: Article

References (43)

1. Garcia MJ, McNamara PM, Gordon T, Kannel WB. Morbidity and mortality in diabetics in the Framingham population. Sixteen year follow-up study. Diabetes 1974;23:105-111
2. Kannel WB, McGee DL. Diabetes and cardiovascular disease. The Fra-mingham study. JAMA 1979;241:2035-2038
3. Devereux RB, Roman MJ, Paranicas M, et al. Impact of diabetes on cardiac structure and function: the strong heart study. Circulation 2000;101:2271-2276
4. Bella JN, Devereux RB, Roman MJ, et al. Separate and joint effects of systemic hypertension and diabetes mellitus on left ventricular structure and function in American Indians (the Strong Heart Study). Am J Cardiol 2001;87:1260-1265
5. Gjesdal O, Bluemke DA, Lima JA. Cardiac remodeling at the population level-risk factors, screening, and outcomes. Nat Rev Cardiol 2011;8:673-685
6. Bluemke DA, Kronmal RA, Lima JAC, et al. The relationship of left ventricular mass and geometry to incident cardiovascular events: the MESA (MultiEthnic Study of Atherosclerosis) Study. J Am Coll Cardiol 2008;52:2148-2155
7. Dweck MR, Joshi S, Murigu T, et al. Left ventricular remodeling and hypertrophy in patients with aortic stenosis: insights from cardiovascular magnetic resonance. J Cardiovasc Magn Reson 2012;14:50
8. Gao H, Feng XJ, Li ZM, et al. Downregulation of adipose triglyceride lipase promotes cardiomyocyte hypertrophy by triggering the accumulation of ceram-ides. Arch Biochem Biophys 2015;565:76-88
9. Glenn DJ, Cardema MC, Ni W, et al. Cardiac steatosis potentiates angiotensin II effects in the heart. Am J Physiol Heart Circ Physiol 2015;308:H339-H350
10. Glenn DJ, Wang F, Nishimoto M, et al. A murine model of isolated cardiac steatosis leads to cardiomyopathy. Hypertension 2011;57:216-222
11. Szczepaniak LS, Dobbins RL, Metzger GJ, et al. Myocardial triglycerides and systolic function in humans: in vivo evaluation by localized proton spectroscopy and cardiac imaging. Magn Reson Med 2003;49:417-423
12. Nelson MD, Victor RG, Szczepaniak EW, Simha V, Garg A, Szczepaniak LS. Cardiac steatosis and left ventricular hypertrophy in patients with generalized lipodystrophy as determined by magnetic resonance spectroscopy and imaging. Am J Cardiol 2013;112:1019-1024
13. 1H-magnetic resonance spectroscopy study. Circulation 2007;116:1170-1175
14. Scheuermann-Freestone M, Madsen PL, Manners D, et al. Abnormal cardiac and skeletal muscle energy metabolism in patients with type 2 diabetes. Circulation 2003;107:3040-3046
15. Neubauer S, Horn M, Cramer M, et al. Myocardial phosphocreatine-to-ATP ratio is a predictor of mortality in patients with dilated cardiomyopathy. Circulation 1997;96:2190-2196
16. Weber KT, Brilla CG. Pathological hypertrophy and cardiac interstitium. Fi-brosis and renin-angiotensin-aldosterone system. Circulation 1991;83:1849-1865
17. Rubler S, Dlugash J, Yuceoglu YZ, Kumral T, Branwood AW, Grishman A. New type of cardiomyopathy associated with diabetic glomerulosclerosis. Am J Cardiol 1972;30:595-602
18. van Heerebeek L, Hamdani N, Handoko ML, et al. Diastolic stiffness of the failing diabetic heart: importance of fibrosis, advanced glycation end products, and myocyte resting tension. Circulation 2008;117:43-51
19. White SK, Sado DM, Fontana M, et al. T1 mapping for myocardial extracellular volume measurement by CMR: bolus only versus primed infusion technique. JACC Cardiovasc Imaging 2013;6:955-962
20. Liu S, Han J, Nacif MS, et al. Diffuse myocardial fibrosis evaluation using cardiac magnetic resonance T1 mapping: sample size considerations for clinical trials. J Cardiovasc Magn Reson 2012;14:90
21. Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 1998;15:539-553
22. Rider OJ, Tayal U, Francis JM, et al. The effect of obesity and weight loss on aortic pulse wave velocity as assessed by magnetic resonance imaging. Obesity (Silver Spring) 2010;18:2311-2316
23. American Diabetes Association. Standards of medical care in diabetes- 2007. Diabetes Care 2007;30(Suppl. 1):S4-S41
24. Abbara S, Arbab-Zadeh A, Callister TQ, et al. SCCT guidelines for performance of coronary computed tomographic angiography: a report of the Society of Cardiovascular Computed Tomography Guidelines Committee. J Cardiovasc Comput Tomogr 2009;3:190-204
25. Baumgartner H, Hung J, Bermejo J, et al.; American Society of Echocar-diography; European Association of Echocardiography. Echocardiographic assessment of valve stenosis: EAE/ASE recommendations for clinical practice. J Am Soc Echocardiogr 2009;22:1-23; quiz 101-102
26. Rider OJ, Lewandowski A, Nethononda R, et al. Gender-specific differences in left ventricular remodelling in obesity: insights from cardiovascular magnetic resonance imaging. Eur Heart J 2013;34:292-299
27. Lawton JS, Cupps BP, Knutsen AK, et al. Magnetic resonance imaging detects significant sex differences in human myocardial strain. Biomed Eng Online 2011;10:76
28. Stuber M, Spiegel MA, Fischer SE, et al. Single breath-hold slice-following CSPAMM myocardial tagging. MAGMA 1999;9:85-91
29. Piechnik SK, Ferreira VM, Dall'Armellina E, et al. Shortened Modified Look-Locker Inversion recovery (ShMOLLI) for clinical myocardial T1-mapping at 1.5 and 3 T within a 9 heartbeat breathhold. J Cardiovasc Magn Reson 2010;12:69
30. Flett AS, Hayward MP, Ashworth MT, et al. Equilibrium contrast cardiovascular magnetic resonance for the measurement of diffuse myo-cardial fibrosis: preliminary validation in humans. Circulation 2010;122: 138-144
31. Ntusi NA, Piechnik SK, Francis JM, et al. Subclinical myocardial inflammation and diffuse fibrosis are common in systemic sclerosis-a clinical study using myocardial T1-mapping and extracellular volume quantification. J Cardiovasc Magn Reson 2014;16:21
32. Purvis LAB, Clarke WT, Biasiolli L, Robson MD, Rodgers CT. Linewidth constraints in Matlab AMARES using per-metabolite T2 and per-voxel DB0. Concord, CA, ISMRM, 2014, p. 2885
33. Rial B, Robson MD, Neubauer S, Schneider JE. Rapid quantification of myocardial lipid content in humans using single breath-hold 1H MRS at 3 Tesla. Magn Reson Med 2011;66:619-624
34. Verdecchia P, Schillaci G, Borgioni C, et al. Prognostic value of left ventricular mass and geometry in systemic hypertension with left ventricular hypertrophy. Am J Cardiol 1996;78:197-202
35. Rosen BD, Edvardsen T, Lai S, et al. Left ventricular concentric remodeling is associated with decreased global and regional systolic function: the MultiEthnic Study of Atherosclerosis. Circulation 2005;112:984-991
36. Shivu GN, Phan TT, Abozguia K, et al. Relationship between coronary mi-crovascular dysfunction and cardiac energetics impairment in type 1 diabetes mellitus. Circulation 2010;121:1209-1215
37. Monji A, Mitsui T, Bando YK, Aoyama M, Shigeta T, Murohara T. Glucagon-like peptide-1 receptor activation reverses cardiac remodeling via normalizing cardiac steatosis and oxidative stress in type 2 diabetes. Am J Physiol Heart Circ Physiol 2013;305:H295-H304
38. Ramírez E, Klett-Mingo M, Ares-Carrasco S, et al. Eplerenone attenuated cardiac steatosis, apoptosis and diastolic dysfunction in experimental type-II diabetes. Cardiovasc Diabetol 2013;12:172
39. Damsgaard EM, Frøland A, Jørgensen OD, Morgensen CE. Prognostic value of urinary albumin excretion rate and other risk factors in elderly diabetic patients and non-diabetic control subjects surviving the first 5 years after assessment. Diabetologia 1993;36:1030-1036
40. Turkbey EB, McClelland RL, Kronmal RA, et al. The impact of obesity on the left ventricle: the Multi-Ethnic Study of Atherosclerosis (MESA). JACC Cardiovasc Imaging 2010;3:266-274
41. Finck BN, Lehman JJ, Leone TC, et al. The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus. J Clin Invest 2002;109:121-130
42. Schmieder RE, Hilgers KF, Schlaich MP, Schmidt BMW. Renin-angiotensin system and cardiovascular risk. Lancet 2007;369:1208-1219
43. Boudina S, Abel ED. Diabetic cardiomyopathy revisited. Circulation 2007; 115:3213-3223