메뉴 건너뛰기




Volumn 11, Issue 2, 2019, Pages

Targeting IL-10 family cytokines for the treatment of human diseases

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 10;

EID: 85060906306     PISSN: None     EISSN: 19430264     Source Type: Journal    
DOI: 10.1101/cshperspect.a028548     Document Type: Article
Times cited : (197)

References (261)
  • 2
    • 0032822627 scopus 로고    scopus 로고
    • IL-10 expression by CT26 colon carcinoma cells inhibits their malignant phenotype and induces a T-cell-mediated tu-tu-mor rejection in the context of a systemic Th2 response
    • mor
    • Adris S, Klein S, Jasnis M, Chuluyan E, Ledda M, Bravo A, Carbone C, Chernajovsky Y, Podhajcer O. 1999. IL-10 expression by CT26 colon carcinoma cells inhibits their malignant phenotype and induces a T-cell-mediated tu-tu-mor rejection in the context of a systemic Th2 response. Gene Ther 6: 1705–1712. mor
    • (1999) Gene Ther , vol.6 , pp. 1705-1712
    • Adris, S.1    Klein, S.2    Jasnis, M.3    Chuluyan, E.4    Ledda, M.5    Bravo, A.6    Carbone, C.7    Chernajovsky, Y.8    Podhajcer, O.9
  • 4
    • 77950243426 scopus 로고    scopus 로고
    • Expression of IL-10 family cytokines in rheumatoid arthritis: Elevated levels of IL-19 in the joints
    • Alanärä T, Karstila K, Moilanen T, Silvennoinen O, Isomäki P. 2010. Expression of IL-10 family cytokines in rheumatoid arthritis: Elevated levels of IL-19 in the joints. Scand J Rheumatol 39: 118–126.
    • (2010) Scand J Rheumatol , vol.39 , pp. 118-126
    • Alanärä, T.1    Karstila, K.2    Moilanen, T.3    Silvennoinen, O.4    Isomäki, P.5
  • 6
    • 33646185492 scopus 로고    scopus 로고
    • Lambda interferon (IFN-λ), a type III IFN, is induced by viruses and IFNs and displays potent antiviral activity against select virus infections in vivo
    • Ank N, West H, Bartholdy C, Eriksson K, Thomsen AR, Paludan SR. 2006. Lambda interferon (IFN-λ), a type III IFN, is induced by viruses and IFNs and displays potent antiviral activity against select virus infections in vivo. J Virol 80: 4501–4509.
    • (2006) J Virol , vol.80 , pp. 4501-4509
    • Ank, N.1    West, H.2    Bartholdy, C.3    Eriksson, K.4    Thomsen, A.R.5    Paludan, S.R.6
  • 8
    • 0038283161 scopus 로고    scopus 로고
    • Interleukin-10 ther-apy—Review of a new approach
    • Asadullah K, Sterry W, Volk H-D. 2003. Interleukin-10 ther-apy—Review of a new approach. Pharmacol Rev 55: 241– 269.
    • (2003) Pharmacol Rev , vol.55 , pp. 241-269
    • Asadullah, K.1    Sterry, W.2    Volk, H.-D.3
  • 10
    • 84871172866 scopus 로고    scopus 로고
    • Classification of acute pancreatitis—2012: Revision of the Atlanta classification and definitions by international consensus
    • Banks PA, Bollen TL, Dervenis C, Gooszen HG, Johnson CD, Sarr MG, Tsiotos GG, Vege SS; Acute Pancreatitis Classification Working Group. 2013. Classification of acute pancreatitis—2012: Revision of the Atlanta classification and definitions by international consensus. Gut 62: 102–111.
    • (2013) Gut , vol.62 , pp. 102-111
    • Banks, P.A.1    Bollen, T.L.2    Dervenis, C.3    Gooszen, H.G.4    Johnson, C.D.5    Sarr, M.G.6    Tsiotos, G.G.7    Vege, S.S.8
  • 11
    • 84885839639 scopus 로고    scopus 로고
    • Development of a stress-inducible controlled expression (SICE) system in Lactococcus lactis for the production and delivery of therapeutic molecules at mucosal surfaces
    • Benbouziane B, Ribelles P, Aubry C, Martin R, Kharrat P, Riazi A, Langella P, Bermúdez-Humarán LG. 2013. Development of a stress-inducible controlled expression (SICE) system in Lactococcus lactis for the production and delivery of therapeutic molecules at mucosal surfaces. J Biotechnol 168: 120–129.
    • (2013) J Biotechnol , vol.168 , pp. 120-129
    • Benbouziane, B.1    Ribelles, P.2    Aubry, C.3    Martin, R.4    Kharrat, P.5    Riazi, A.6    Langella, P.7    Bermúdez-Humarán, L.G.8
  • 13
    • 14844342604 scopus 로고    scopus 로고
    • IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes
    • Boniface K, Bernard FX, Garcia M, Gurney AL, Lecron JC, Morel F. 2005. IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes. J Immunol 174: 3695– 3702.
    • (2005) J Immunol , vol.174 , pp. 3695-3702
    • Boniface, K.1    Bernard, F.X.2    Garcia, M.3    Gurney, A.L.4    Lecron, J.C.5    Morel, F.6
  • 16
    • 84868542644 scopus 로고    scopus 로고
    • Expression of IL-24 and IL-24 receptors in human wound tissues and the biological implications of IL-24 on keratinocytes
    • Bosanquet DC, Harding KG, Ruge F, Sanders AJ, Jiang WG. 2012. Expression of IL-24 and IL-24 receptors in human wound tissues and the biological implications of IL-24 on keratinocytes. Wound Repair Regen 20: 896–903.
    • (2012) Wound Repair Regen , vol.20 , pp. 896-903
    • Bosanquet, D.C.1    Harding, K.G.2    Ruge, F.3    Sanders, A.J.4    Jiang, W.G.5
  • 20
    • 34248225758 scopus 로고    scopus 로고
    • Cellular and molecular basis of wound healing in diabetes
    • Brem H, Tomic-Canic M. 2007. Cellular and molecular basis of wound healing in diabetes. J Clin Invest 117: 1219– 1222.
    • (2007) J Clin Invest , vol.117 , pp. 1219-1222
    • Brem, H.1    Tomic-Canic, M.2
  • 22
    • 84880018473 scopus 로고    scopus 로고
    • Usp18 deficient mammary epithelial cells create an antitumour environment driven by hypersensitivity to IFN-λ and elevated secretion of Cxcl10
    • Burkart C, Arimoto KI, Tang T, Cong X, Xiao N, Liu YC, Kotenko SV, Ellies LG, Zhang DE. 2013. Usp18 deficient mammary epithelial cells create an antitumour environment driven by hypersensitivity to IFN-λ and elevated secretion of Cxcl10. EMBO Mol Med 5: 1035–1050.
    • (2013) EMBO Mol Med , vol.5 , pp. 1035-1050
    • Burkart, C.1    Arimoto, K.I.2    Tang, T.3    Cong, X.4    Xiao, N.5    Liu, Y.C.6    Kotenko, S.V.7    Ellies, L.G.8    Zhang, D.E.9
  • 23
    • 44949162009 scopus 로고    scopus 로고
    • Recombinant human interleukin 10 for induction of remission in Crohn’s disease
    • Buruiana FE, Solà I, Alonso-Coello P. 2010. Recombinant human interleukin 10 for induction of remission in Crohn’s disease. Cochrane Database Syst Rev 119: CD005109.
    • (2010) Cochrane Database Syst Rev , vol.119
    • Buruiana, F.E.1    Solà, I.2    Alonso-Coello, P.3
  • 24
    • 0029742433 scopus 로고    scopus 로고
    • IL-10 fails to abrogate experimental autoimmune encephalomyelitis
    • Cannella B, Gao YL, Brosnan C, Raine CS. 1996. IL-10 fails to abrogate experimental autoimmune encephalomyelitis. J Neurosci Res 45: 735–746.
    • (1996) J Neurosci Res , vol.45 , pp. 735-746
    • Cannella, B.1    Gao, Y.L.2    Brosnan, C.3    Raine, C.S.4
  • 26
    • 0027517422 scopus 로고
    • Interleukin 10 (IL-10) inhibits the release of proinflammatory cytokines from human polymorphonuclear leukocytes. Evidence for an autocrine role of tumor necrosis factor and IL-1 β in mediating the production of IL-8 triggered by lipopolysaccharide
    • Cassatella MA, Meda L, Bonora S, Ceska M, Constantin G. 1993. Interleukin 10 (IL-10) inhibits the release of proinflammatory cytokines from human polymorphonuclear leukocytes. Evidence for an autocrine role of tumor necrosis factor and IL-1 β in mediating the production of IL-8 triggered by lipopolysaccharide. J Exp Med 178: 2207– 2211.
    • (1993) J Exp Med , vol.178 , pp. 2207-2211
    • Cassatella, M.A.1    Meda, L.2    Bonora, S.3    Ceska, M.4    Constantin, G.5
  • 27
    • 0037097637 scopus 로고    scopus 로고
    • The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory activity and is designated IL-24
    • Caudell EG, Mumm JB, Poindexter N, Ekmekcioglu S, Mhashilkar AM, Yang XH, Retter MW, Hill P, Chada S, Grimm EA. 2002. The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory activity and is designated IL-24. J Immunol 168: 6041–6046.
    • (2002) J Immunol , vol.168 , pp. 6041-6046
    • Caudell, E.G.1    Mumm, J.B.2    Poindexter, N.3    Ekmekcioglu, S.4    Mhashilkar, A.M.5    Yang, X.H.6    Retter, M.W.7    Hill, P.8    Chada, S.9    Grimm, E.A.10
  • 29
    • 85016548232 scopus 로고    scopus 로고
    • Elements of cancer immunity and the cancer-immune set point
    • Chen DS, Mellman I. 2017. Elements of cancer immunity and the cancer-immune set point. Nature 541: 321–330.
    • (2017) Nature , vol.541 , pp. 321-330
    • Chen, D.S.1    Mellman, I.2
  • 33
    • 0030048535 scopus 로고    scopus 로고
    • Differential modulation of B7–1 and B7–2 isoform expression on human monocytes by cytokines which influence the development of T helper cell phenotype
    • Creery WD, Diaz-Mitoma F, Filion L, Kumar A. 1996. Differential modulation of B7–1 and B7–2 isoform expression on human monocytes by cytokines which influence the development of T helper cell phenotype. Eur J Immunol 26: 1273–1277.
    • (1996) Eur J Immunol , vol.26 , pp. 1273-1277
    • Creery, W.D.1    Diaz-Mitoma, F.2    Filion, L.3    Kumar, A.4
  • 34
    • 19944379432 scopus 로고    scopus 로고
    • Clinical and local biological effects of an intratumoral injection of mda-7 (IL24; INGN 241) in patients with advanced carcinoma: A phase I study
    • Cunningham CC, Chada S, Merritt JA, Tong A, Senzer N, Zhang Y, Mhashilkar A, Parker K, Vukelja S, Richards D, et al. 2005. Clinical and local biological effects of an intratumoral injection of mda-7 (IL24; INGN 241) in patients with advanced carcinoma: A phase I study. Mol Ther 11: 149–159.
    • (2005) Mol Ther , vol.11 , pp. 149-159
    • Cunningham, C.C.1    Chada, S.2    Merritt, J.A.3    Tong, A.4    Senzer, N.5    Zhang, Y.6    Mhashilkar, A.7    Parker, K.8    Vukelja, S.9    Richards, D.10
  • 36
    • 0027240219 scopus 로고
    • Interleukin 10 (IL-10) inhibits human lymphocyte interferon λ-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells
    • D’Andrea A, Aste-Amezaga M, Valiante NM, Ma X, Kubin M, Trinchieri G. 1993. Interleukin 10 (IL-10) inhibits human lymphocyte interferon λ-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells. J Exp Med 178: 1041–1048.
    • (1993) J Exp Med , vol.178 , pp. 1041-1048
    • D’Andrea, A.1    Aste-Amezaga, M.2    Valiante, N.M.3    Ma, X.4    Kubin, M.5    Trinchieri, G.6
  • 38
    • 0033663130 scopus 로고    scopus 로고
    • In vivo effects of recombinant human interleukin-10 on lymphocyte phenotypes and leukocyte activation markers in inflammatory bowel disease
    • Dejaco C, Reinisch W, Lichtenberger C, Waldhoer T, Kuhn I, Tilg H, Gasche C. 2000. In vivo effects of recombinant human interleukin-10 on lymphocyte phenotypes and leukocyte activation markers in inflammatory bowel disease. J Investig Med 48: 449–456.
    • (2000) J Investig Med , vol.48 , pp. 449-456
    • Dejaco, C.1    Reinisch, W.2    Lichtenberger, C.3    Waldhoer, T.4    Kuhn, I.5    Tilg, H.6    Gasche, C.7
  • 41
    • 0026094306 scopus 로고
    • Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: An autoregulatory role of IL-10 produced by monocytes
    • de Waal-Malefyt R, Abrams J, Bennett B, Figdor CG, de Vries JE. 1991a. Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: An autoregulatory role of IL-10 produced by monocytes. J Exp Med 174: 1209– 1220.
    • (1991) J Exp Med , vol.174 , pp. 1209-1220
    • de Waal-Malefyt, R.1    Abrams, J.2    Bennett, B.3    Figdor, C.G.4    de Vries, J.E.5
  • 42
    • 0026000892 scopus 로고
    • Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression
    • de Waal-Malefyt R, Haanen J, Spits H, Roncarolo MG, Velde Te A, Figdor C, Johnson K, Kastelein R, Yssel H, de Vries JE. 1991b. Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression. J Exp Med 174: 915–924.
    • (1991) J Exp Med , vol.174 , pp. 915-924
    • de Waal-Malefyt, R.1    Haanen, J.2    Spits, H.3    Roncarolo, M.G.4    Velde Te, A.5    Figdor, C.6    Johnson, K.7    Kastelein, R.8    Yssel, H.9    de Vries, J.E.10
  • 43
    • 84884603722 scopus 로고    scopus 로고
    • Murine analogues of etanercept and of F8-IL10 inhibit the progression of collagen-induced arthritis in the mouse
    • Doll F, Schwager K, Hemmerle T, Neri D. 2013. Murine analogues of etanercept and of F8-IL10 inhibit the progression of collagen-induced arthritis in the mouse. Arthritis Res Ther 15: R138.
    • (2013) Arthritis Res Ther , vol.15 , pp. R138
    • Doll, F.1    Schwager, K.2    Hemmerle, T.3    Neri, D.4
  • 44
    • 0032729983 scopus 로고    scopus 로고
    • Survival, physiology, and lysis of Lactococcus lactis in the digestive tract
    • Drouault S, Corthier G, Ehrlich SD, Renault P. 1999. Survival, physiology, and lysis of Lactococcus lactis in the digestive tract. Appl Environ Microbiol 65: 4881–4886.
    • (1999) Appl Environ Microbiol , vol.65 , pp. 4881-4886
    • Drouault, S.1    Corthier, G.2    Ehrlich, S.D.3    Renault, P.4
  • 46
    • 84881658991 scopus 로고    scopus 로고
    • Interferon induction and function at the mucosal surface
    • Durbin RK, Kotenko SV, Durbin JE. 2013. Interferon induction and function at the mucosal surface. Immunol Rev 255: 25–39.
    • (2013) Immunol Rev , vol.255 , pp. 25-39
    • Durbin, R.K.1    Kotenko, S.V.2    Durbin, J.E.3
  • 48
    • 66149138884 scopus 로고    scopus 로고
    • Historical perspective and recent insights into our understanding of the molecular and biochemical basis of the antitumor properties of mda-7/IL-24
    • Emdad L, Lebedeva IV, Su ZZ, Gupta P, Sauane M, Dash R, Grant S, Dent P, Curiel DT, Sarkar D, et al. 2009. Historical perspective and recent insights into our understanding of the molecular and biochemical basis of the antitumor properties of mda-7/IL-24. Cancer Biol Ther 8: 391– 400.
    • (2009) Cancer Biol Ther , vol.8 , pp. 391-400
    • Emdad, L.1    Lebedeva, I.V.2    Su, Z.Z.3    Gupta, P.4    Sauane, M.5    Dash, R.6    Grant, S.7    Dent, P.8    Curiel, D.T.9    Sarkar, D.10
  • 51
    • 27744448125 scopus 로고    scopus 로고
    • Wound healing and its impairment in the diabetic foot
    • Falanga V. 2005. Wound healing and its impairment in the diabetic foot. Lancet 366: 1736–1743.
    • (2005) Lancet , vol.366 , pp. 1736-1743
    • Falanga, V.1
  • 53
    • 0034463305 scopus 로고    scopus 로고
    • Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn’s disease. The Interleukin 10 Inflammatory Bowel Disease Cooperative Study Group
    • Fedorak RN, Gangl A, Elson CO, Rutgeerts P, Schreiber S, Wild G, Hanauer SB, Kilian A, Cohard M, LeBeaut A, et al. 2000. Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn’s disease. The Interleukin 10 Inflammatory Bowel Disease Cooperative Study Group. Gastroenterology 119: 1473– 1482.
    • (2000) Gastroenterology , vol.119 , pp. 1473-1482
    • Fedorak, R.N.1    Gangl, A.2    Elson, C.O.3    Rutgeerts, P.4    Schreiber, S.5    Wild, G.6    Hanauer, S.B.7    Kilian, A.8    Cohard, M.9    Lebeaut, A.10
  • 54
    • 84862769727 scopus 로고    scopus 로고
    • Interleukin-22 promotes proliferation of liver stem/progenitor cells in mice and patients with chronic hepatitis B virus infection
    • Feng D, Kong X, Weng H, Park O, Wang H, Dooley S, Gershwin ME, Gao B. 2012a. Interleukin-22 promotes proliferation of liver stem/progenitor cells in mice and patients with chronic hepatitis B virus infection. Gastroenterology 143: 188–198.e7.
    • (2012) Gastroenterology , vol.143 , pp. 188-198
    • Feng, D.1    Kong, X.2    Weng, H.3    Park, O.4    Wang, H.5    Dooley, S.6    Gershwin, M.E.7    Gao, B.8
  • 57
    • 0024408824 scopus 로고
    • Two types of mouse T helper cell. IV: Th2 clones secrete a factor that inhibits cytokine production by Th1 clones
    • Fiorentino DF, Bond MW, Mosmann TR. 1989. Two types of mouse T helper cell. IV: Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med 170: 2081–2095.
    • (1989) J Exp Med , vol.170 , pp. 2081-2095
    • Fiorentino, D.F.1    Bond, M.W.2    Mosmann, T.R.3
  • 59
    • 63749132070 scopus 로고    scopus 로고
    • The role of genomic data in the discovery, annotation and evolutionary interpretation of the interferon-λ family
    • Fox BA, Sheppard PO, O’Hara PJ. 2009. The role of genomic data in the discovery, annotation and evolutionary interpretation of the interferon-λ family. PloS ONE 4: e4933.
    • (2009) Plos ONE , vol.4
    • Fox, B.A.1    Sheppard, P.O.2    O’Hara, P.J.3
  • 62
    • 84937540562 scopus 로고    scopus 로고
    • Targeted delivery of interleukin-10 to chronic cardiac allo-graft rejection using a human antibody specific to the extra domain A of fibronectin
    • Franz M, Doll F, Grün K, Richter P, Köse N, Ziffels B, Schubert H, Figulla HR, Jung C, Gummert J, et al. 2015. Targeted delivery of interleukin-10 to chronic cardiac allo-graft rejection using a human antibody specific to the extra domain A of fibronectin. Int J Cardiol 195: 311–322.
    • (2015) Int J Cardiol , vol.195 , pp. 311-322
    • Franz, M.1    Doll, F.2    Grün, K.3    Richter, P.4    Köse, N.5    Ziffels, B.6    Schubert, H.7    Figulla, H.R.8    Jung, C.9    Gummert, J.10
  • 63
    • 84946728644 scopus 로고    scopus 로고
    • Peginterferon Lambda-1a is associated with a low incidence of autoimmune thyroid disease in chronic hepatitis C
    • Fredlund P, Hillson J, Gray T, Shemanski L, Dimitrova D, Srinivasan S. 2015. Peginterferon Lambda-1a is associated with a low incidence of autoimmune thyroid disease in chronic hepatitis C. J Interferon Cytokine Res 35: 841– 843.
    • (2015) J Interferon Cytokine Res , vol.35 , pp. 841-843
    • Fredlund, P.1    Hillson, J.2    Gray, T.3    Shemanski, L.4    Dimitrova, D.5    Srinivasan, S.6
  • 64
    • 84874030693 scopus 로고    scopus 로고
    • Combinations of λ interferon with direct-acting antiviral agents are highly efficient in suppressing hepatitis C virus replication
    • Friborg J, Levine S, Chen C, Sheaffer AK, Chaniewski S, Voss S, Lemm JA, McPhee F. 2013. Combinations of λ interferon with direct-acting antiviral agents are highly efficient in suppressing hepatitis C virus replication. Antimi-crob Agents Chemother 57: 1312–1322.
    • (2013) Antimi-Crob Agents Chemother , vol.57 , pp. 1312-1322
    • Friborg, J.1    Levine, S.2    Chen, C.3    Sheaffer, A.K.4    Chaniewski, S.5    Voss, S.6    Lemm, J.A.7    McPhee, F.8
  • 65
    • 68949110201 scopus 로고    scopus 로고
    • Interferon-λ is functionally an interferon but structurally related to the interleukin-10 family
    • Gad HH, Dellgren C, Hamming OJ, Vends S, Paludan SR, Hartmann R. 2009. Interferon-λ is functionally an interferon but structurally related to the interleukin-10 family. J Biol Chem 284: 20869–20875.
    • (2009) J Biol Chem , vol.284 , pp. 20869-20875
    • Gad, H.H.1    Dellgren, C.2    Hamming, O.J.3    Vends, S.4    Paludan, S.R.5    Hartmann, R.6
  • 66
    • 84908201258 scopus 로고    scopus 로고
    • A phase IB clinical trial with Dekavil (F8-IL10), an immunoregulatory “armed antibody” for the treatment of rheumatoid arthritis, used in combination wiIh methotrexate
    • Galeazzi M, Bazzichi L, Sebastiani GD, Neri D, Garcia E, Ravenni N, Giovannoni L, Wilton J, Bardelli M, Baldi C, et al. 2014. A phase IB clinical trial with Dekavil (F8-IL10), an immunoregulatory “armed antibody” for the treatment of rheumatoid arthritis, used in combination wiIh methotrexate. Isr Med Assoc J 16: 666.
    • (2014) Isr Med Assoc J , vol.16 , pp. 666
    • Galeazzi, M.1    Bazzichi, L.2    Sebastiani, G.D.3    Neri, D.4    Garcia, E.5    Ravenni, N.6    Giovannoni, L.7    Wilton, J.8    Bardelli, M.9    Baldi, C.10
  • 69
    • 84874244715 scopus 로고    scopus 로고
    • IFN-α subtypes: Distinct biological activities in anti-viral therapy
    • Gibbert K, Schlaak JF, Yang D, Dittmer U. 2013. IFN-α subtypes: Distinct biological activities in anti-viral therapy. Br J Pharmacol 168: 1048–1058.
    • (2013) Br J Pharmacol , vol.168 , pp. 1048-1058
    • Gibbert, K.1    Schlaak, J.F.2    Yang, D.3    Dittmer, U.4
  • 72
    • 84941991984 scopus 로고    scopus 로고
    • First-in-human, phase 1, randomized, dose-escalation trial with recombinant anti-IL-20 monoclonal antibody in patients with psoriasis
    • Gottlieb AB, Krueger JG, Sandberg Lundblad M, Göthberg M, Skolnick BE. 2015. First-in-human, phase 1, randomized, dose-escalation trial with recombinant anti-IL-20 monoclonal antibody in patients with psoriasis. PloS ONE 10: e0134703.
    • (2015) Plos ONE , vol.10
    • Gottlieb, A.B.1    Krueger, J.G.2    Sandberg Lundblad, M.3    Göthberg, M.4    Skolnick, B.E.5
  • 81
    • 77949889459 scopus 로고    scopus 로고
    • IL-24 transgenic mice: In vivo evidence of overlapping functions for IL-20, IL-22, and IL-24 in the epidermis
    • He M, Liang P. 2010. IL-24 transgenic mice: In vivo evidence of overlapping functions for IL-20, IL-22, and IL-24 in the epidermis. J Immunol 184: 1793–1798.
    • (2010) J Immunol , vol.184 , pp. 1793-1798
    • He, M.1    Liang, P.2
  • 83
    • 64049087021 scopus 로고    scopus 로고
    • Lambda interferon inhibits human immunodefi-ciency virus type 1 infection of macrophages
    • Hou W, Wang X, Ye L, Zhou L, Yang Z-Q, Riedel E, Ho WZ. 2009. Lambda interferon inhibits human immunodefi-ciency virus type 1 infection of macrophages. J Virol 83: 3834–3842.
    • (2009) J Virol , vol.83 , pp. 3834-3842
    • Hou, W.1    Wang, X.2    Ye, L.3    Zhou, L.4    Yang, Z.-Q.5    Riedel, E.6    Ho, W.Z.7
  • 85
    • 84857551794 scopus 로고    scopus 로고
    • Interleukin-19 blockade attenuates collagen-induced arthritis in rats
    • Hsu YH, Hsieh PP, Chang MS. 2012. Interleukin-19 blockade attenuates collagen-induced arthritis in rats. Rheumatology (Oxford) 51: 434–442.
    • (2012) Rheumatology (Oxford) , vol.51 , pp. 434-442
    • Hsu, Y.H.1    Hsieh, P.P.2    Chang, M.S.3
  • 89
    • 0030031182 scopus 로고    scopus 로고
    • Pharmacoki-netics and immunomodulatory properties of intravenously administered recombinant human interleukin-10 in healthy volunteers
    • Huhn RD, Radwanski E, O’Connell SM, Sturgill MG, Clarke L, Cody RP, Affrime MB, Cutler DL. 1996. Pharmacoki-netics and immunomodulatory properties of intravenously administered recombinant human interleukin-10 in healthy volunteers. Blood 87: 699–705.
    • (1996) Blood , vol.87 , pp. 699-705
    • Huhn, R.D.1    Radwanski, E.2    O’Connell, S.M.3    Sturgill, M.G.4    Clarke, L.5    Cody, R.P.6    Affrime, M.B.7    Cutler, D.L.8
  • 92
    • 17244381180 scopus 로고    scopus 로고
    • Expression of interleukin-22 in rheumatoid arthritis: Potential role as a proinflammatory cytokine
    • Ikeuchi H, Kuroiwa T, Hiramatsu N, Kaneko Y, Hiromura K, Ueki K, Nojima Y. 2005. Expression of interleukin-22 in rheumatoid arthritis: Potential role as a proinflammatory cytokine. Arthritis Rheum 52: 1037–1046.
    • (2005) Arthritis Rheum , vol.52 , pp. 1037-1046
    • Ikeuchi, H.1    Kuroiwa, T.2    Hiramatsu, N.3    Kaneko, Y.4    Hiromura, K.5    Ueki, K.6    Nojima, Y.7
  • 93
    • 67650500615 scopus 로고    scopus 로고
    • Lactococcus lactis expressing either Staphylococcus aureus fibronectin-binding protein AorListeria monocytogenes internalin A can efficiently internalize and deliver DNA in human epithelial cells
    • Innocentin S, Guimarães V, Miyoshi A, Azevedo V, Langella P, Chatel JM, Lefèvre F. 2009. Lactococcus lactis expressing either Staphylococcus aureus fibronectin-binding protein AorListeria monocytogenes internalin A can efficiently internalize and deliver DNA in human epithelial cells. Appl Environ Microbiol 75: 4870–4878.
    • (2009) Appl Environ Microbiol , vol.75 , pp. 4870-4878
    • Innocentin, S.1    Guimarães, V.2    Miyoshi, A.3    Azevedo, V.4    Langella, P.5    Chatel, J.M.6    Lefèvre, F.7
  • 94
    • 0029069423 scopus 로고
    • The role of IL-10 in human B cell activation, proliferation, and differentiation
    • Itoh K, Hirohata S. 1995. The role of IL-10 in human B cell activation, proliferation, and differentiation. J Immunol 154: 4341–4350.
    • (1995) J Immunol , vol.154 , pp. 4341-4350
    • Itoh, K.1    Hirohata, S.2
  • 96
    • 0037961580 scopus 로고    scopus 로고
    • Diabetic foot ulcers
    • Jeffcoate WJ, Harding KG. 2003. Diabetic foot ulcers. Lancet 361: 1545–1551.
    • (2003) Lancet , vol.361 , pp. 1545-1551
    • Jeffcoate, W.J.1    Harding, K.G.2
  • 97
    • 0029558740 scopus 로고
    • Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression
    • Jiang H, Lin JJ, Su ZZ, Goldstein NI, Fisher PB. 1995. Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression. Oncogene 11: 2477–2486.
    • (1995) Oncogene , vol.11 , pp. 2477-2486
    • Jiang, H.1    Lin, J.J.2    Su, Z.Z.3    Goldstein, N.I.4    Fisher, P.B.5
  • 100
    • 84899835126 scopus 로고    scopus 로고
    • Endogenous IL-22 plays a dual role in arthritis: Regulation of established arthritis via IFN-γ responses
    • Justa S, Zhou X, Sarkar S. 2014. Endogenous IL-22 plays a dual role in arthritis: Regulation of established arthritis via IFN-γ responses. PloS ONE 9: e93279.
    • (2014) Plos ONE , vol.9
    • Justa, S.1    Zhou, X.2    Sarkar, S.3
  • 105
    • 77957946415 scopus 로고    scopus 로고
    • Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: Role of signal transducer and activator of transcription 3
    • Ki SH, Park O, Zheng M, Morales-Ibanez O, Kolls JK, Batal-ler R, Gao B. 2010. Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: Role of signal transducer and activator of transcription 3. Hepatology 52: 1291–1300.
    • (2010) Hepatology , vol.52 , pp. 1291-1300
    • Ki, S.H.1    Park, O.2    Zheng, M.3    Morales-Ibanez, O.4    Kolls, J.K.5    Batal-Ler, R.6    Gao, B.7
  • 109
    • 84925014280 scopus 로고    scopus 로고
    • New drugs and treatment targets in psoriasis
    • Kofoed K, Skov L, Zachariae C. 2015. New drugs and treatment targets in psoriasis. Acta Derm Venereol 95: 133–139.
    • (2015) Acta Derm Venereol , vol.95 , pp. 133-139
    • Kofoed, K.1    Skov, L.2    Zachariae, C.3
  • 111
    • 84944570278 scopus 로고    scopus 로고
    • Innate lymphoid cells in graft-versus-host disease
    • Konya V, Mjösberg J. 2015. Innate lymphoid cells in graft-versus-host disease. Am J Transplant 15: 2795–2801.
    • (2015) Am J Transplant , vol.15 , pp. 2795-2801
    • Konya, V.1    Mjösberg, J.2
  • 112
    • 0038189842 scopus 로고    scopus 로고
    • IL-23 production by cosecretion of endogenous p19 and transgenic p40 in keratin 14/p40 transgenic mice: Evidence for enhanced cutaneous immunity
    • Kopp T, Lenz P, Bello-Fernandez C, Kastelein RA, Kupper TS, Stingl G. 2003. IL-23 production by cosecretion of endogenous p19 and transgenic p40 in keratin 14/p40 transgenic mice: Evidence for enhanced cutaneous immunity. J Immunol 170: 5438–5444.
    • (2003) J Immunol , vol.170 , pp. 5438-5444
    • Kopp, T.1    Lenz, P.2    Bello-Fernandez, C.3    Kastelein, R.A.4    Kupper, T.S.5    Stingl, G.6
  • 114
    • 37449013636 scopus 로고    scopus 로고
    • The expression of IL-20 and IL-24 and their shared receptors are increased in rheumatoid arthritis and spondyloarthropathy
    • Kragstrup TW, Otkjaer K, Holm C, Jørgensen A, Hokland M, Iversen L, Deleuran B. 2008. The expression of IL-20 and IL-24 and their shared receptors are increased in rheumatoid arthritis and spondyloarthropathy. Cytokine 41: 16–23.
    • (2008) Cytokine , vol.41 , pp. 16-23
    • Kragstrup, T.W.1    Otkjaer, K.2    Holm, C.3    Jørgensen, A.4    Hokland, M.5    Iversen, L.6    Deleuran, B.7
  • 116
    • 57149138049 scopus 로고    scopus 로고
    • IL-24: A classic cytokine and/or a potential cure for cancer?
    • Kreis S, Philippidou D, Margue C, Behrmann I. 2008. IL-24: A classic cytokine and/or a potential cure for cancer? J Cell Mol Med 12: 2505–2510.
    • (2008) J Cell Mol Med , vol.12 , pp. 2505-2510
    • Kreis, S.1    Philippidou, D.2    Margue, C.3    Behrmann, I.4
  • 117
    • 0027521572 scopus 로고
    • Interleukin-10-deficient mice develop chronic enterocolitis
    • Kühn R, Löhler J, Rennick D, Rajewsky K, Muller W. 1993. Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75: 263–274.
    • (1993) Cell , vol.75 , pp. 263-274
    • Kühn, R.1    Löhler, J.2    Rennick, D.3    Rajewsky, K.4    Muller, W.5
  • 122
    • 0028084441 scopus 로고
    • Interleukin-10 prevents spontaneous death of germinal center B cells by induction of the bcl-2 protein
    • Levy Y, Brouet JC. 1994. Interleukin-10 prevents spontaneous death of germinal center B cells by induction of the bcl-2 protein. J Clin Invest 93: 424–428.
    • (1994) J Clin Invest , vol.93 , pp. 424-428
    • Levy, Y.1    Brouet, J.C.2
  • 123
    • 33846627240 scopus 로고    scopus 로고
    • Pathophysiology of acute wound healing
    • Li J, Chen J, Kirsner R. 2007. Pathophysiology of acute wound healing. Clin Dermatol 25: 9–18.
    • (2007) Clin Dermatol , vol.25 , pp. 9-18
    • Li, J.1    Chen, J.2    Kirsner, R.3
  • 125
    • 58649110860 scopus 로고    scopus 로고
    • The serine protease marapsin is expressed in stratified squamous epithelia and is up-regulated in the hyper-proliferative epidermis of psoriasis and regenerating wounds
    • Li W, Danilenko DM, Bunting S, Ganesan R, Sa S, Ferrando R, Wu TD, Kolumam GA, Ouyang W, Kirchhofer D. 2009. The serine protease marapsin is expressed in stratified squamous epithelia and is up-regulated in the hyper-proliferative epidermis of psoriasis and regenerating wounds. J Biol Chem 284: 218–228.
    • (2009) J Biol Chem , vol.284 , pp. 218-228
    • Li, W.1    Danilenko, D.M.2    Bunting, S.3    Ganesan, R.4    Sa, S.5    Ferrando, R.6    Wu, T.D.7    Kolumam, G.A.8    Ouyang, W.9    Kirchhofer, D.10
  • 127
    • 33749318470 scopus 로고    scopus 로고
    • Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
    • Liang SC, Tan XY, Luxenberg DP, Karim R, Dunussi-Joannopoulos K, Collins M, Fouser LA. 2006. Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J Exp Med 203: 2271–2279.
    • (2006) J Exp Med , vol.203 , pp. 2271-2279
    • Liang, S.C.1    Tan, X.Y.2    Luxenberg, D.P.3    Karim, R.4    Dunussi-Joannopoulos, K.5    Collins, M.6    Fouser, L.A.7
  • 128
    • 84907966104 scopus 로고    scopus 로고
    • Interferons: Success in anti-viral immunotherapy
    • Lin FC, Young HA. 2014. Interferons: Success in anti-viral immunotherapy. Cytokine Growth Factor Rev 25: 369– 376.
    • (2014) Cytokine Growth Factor Rev , vol.25 , pp. 369-376
    • Lin, F.C.1    Young, H.A.2
  • 134
    • 33845605155 scopus 로고    scopus 로고
    • Interferons α and λ inhibit hepatitis C virus replication with distinct signal transduction and gene regulation kinetics
    • Marcello T, Grakoui A, Barba-Spaeth G, Machlin ES, Kotenko SV, MacDonald MR, Rice CM. 2006. Interferons α and λ inhibit hepatitis C virus replication with distinct signal transduction and gene regulation kinetics. Gastroenterology 131: 1887–1898.
    • (2006) Gastroenterology , vol.131 , pp. 1887-1898
    • Marcello, T.1    Grakoui, A.2    Barba-Spaeth, G.3    Machlin, E.S.4    Kotenko, S.V.5    Macdonald, M.R.6    Rice, C.M.7
  • 135
  • 136
    • 84899876481 scopus 로고    scopus 로고
    • Effects in the use of a genetically engineered strain of Lactococcus lactis delivering in situ IL-10 as a therapy to treat low-grade colon inflammation
    • Martin R, Chain F, Miquel S, Natividad JM, Sokol H, Verdu EF, Langella P, Bermúdez-Humarán LG. 2014. Effects in the use of a genetically engineered strain of Lactococcus lactis delivering in situ IL-10 as a therapy to treat low-grade colon inflammation. Hum Vaccin Immunother 10: 1611–1621.
    • (2014) Hum Vaccin Immunother , vol.10 , pp. 1611-1621
    • Martin, R.1    Chain, F.2    Miquel, S.3    Natividad, J.M.4    Sokol, H.5    Verdu, E.F.6    Langella, P.7    Bermúdez-Humarán, L.G.8
  • 138
    • 21344467289 scopus 로고    scopus 로고
    • Biological activity of interleukins-28 and-29: Comparison with type I interferons
    • Meager A, Visvalingam K, Dilger P, Bryan D, Wadhwa M. 2005. Biological activity of interleukins-28 and-29: Comparison with type I interferons. Cytokine 31: 109–118.
    • (2005) Cytokine , vol.31 , pp. 109-118
    • Meager, A.1    Visvalingam, K.2    Dilger, P.3    Bryan, D.4    Wadhwa, M.5
  • 139
    • 34848870970 scopus 로고    scopus 로고
    • Db/db mice exhibit severe wound-healing impairments compared with other murine diabetic strains in a silicone-splinted excisional wound model
    • Michaels J, Churgin SS, Blechman KM, Greives MR, Aarabi S, Galiano RD, Gurtner GC. 2007. db/db mice exhibit severe wound-healing impairments compared with other murine diabetic strains in a silicone-splinted excisional wound model. Wound Repair Regen 15: 665–670.
    • (2007) Wound Repair Regen , vol.15 , pp. 665-670
    • Michaels, J.1    Churgin, S.S.2    Blechman, K.M.3    Greives, M.R.4    Aarabi, S.5    Galiano, R.D.6    Gurtner, G.C.7
  • 144
    • 53049101323 scopus 로고    scopus 로고
    • Interferon-λ contributes to innate immunity of mice against influenza A virus but not against hepatotropic viruses
    • Mordstein M, Kochs G, Dumoutier L, Renauld JC, Paludan SR, Klucher K, Staeheli P. 2008. Interferon-λ contributes to innate immunity of mice against influenza A virus but not against hepatotropic viruses. PloS Pathog 4: e1000151.
    • (2008) Plos Pathog , vol.4
    • Mordstein, M.1    Kochs, G.2    Dumoutier, L.3    Renauld, J.C.4    Paludan, S.R.5    Klucher, K.6    Staeheli, P.7
  • 150
    • 0030862594 scopus 로고    scopus 로고
    • IL-4 abrogates the inhibitory effect of IL-10 on the development of experimental allergic encephalomyelitis in SJL mice
    • Nagelkerken L, Blauw B, Tielemans M. 1997. IL-4 abrogates the inhibitory effect of IL-10 on the development of experimental allergic encephalomyelitis in SJL mice. Int Immunol 9: 1243–1251.
    • (1997) Int Immunol , vol.9 , pp. 1243-1251
    • Nagelkerken, L.1    Blauw, B.2    Tielemans, M.3
  • 152
    • 0035029602 scopus 로고    scopus 로고
    • Comparison of serum interleukin-10 (IL-10) levels between normal volunteers and patients with advanced melanoma
    • Nemunaitis J, Fong T, Shabe P, Martineau D, Ando D. 2001. Comparison of serum interleukin-10 (IL-10) levels between normal volunteers and patients with advanced melanoma. Cancer Invest 19: 239–247.
    • (2001) Cancer Invest , vol.19 , pp. 239-247
    • Nemunaitis, J.1    Fong, T.2    Shabe, P.3    Martineau, D.4    Ando, D.5
  • 158
    • 84897149169 scopus 로고    scopus 로고
    • In search of magic bullets: The golden age of immunotherapeutics
    • O’Shea JJ, Kanno Y, Chan AC. 2014. In search of magic bullets: The golden age of immunotherapeutics. Cell 157: 227–240.
    • (2014) Cell , vol.157 , pp. 227-240
    • O’Shea, J.J.1    Kanno, Y.2    Chan, A.C.3
  • 159
    • 80052966918 scopus 로고    scopus 로고
    • IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentium
    • Ota N, Wong K, Valdez PA, Zheng Y, Crellin NK, Diehl L, Ouyang W. 2011. IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentium. Nat Immunol 12: 941–948.
    • (2011) Nat Immunol , vol.12 , pp. 941-948
    • Ota, N.1    Wong, K.2    Valdez, P.A.3    Zheng, Y.4    Crellin, N.K.5    Diehl, L.6    Ouyang, W.7
  • 161
    • 78649690842 scopus 로고    scopus 로고
    • Distinct roles of IL-22 in human psoriasis and inflammatory bowel disease
    • Ouyang W. 2010. Distinct roles of IL-22 in human psoriasis and inflammatory bowel disease. Cytokine Growth Factor Rev 21: 435–441.
    • (2010) Cytokine Growth Factor Rev , vol.21 , pp. 435-441
    • Ouyang, W.1
  • 162
    • 79953048089 scopus 로고    scopus 로고
    • Regulation and functions of the IL-10 family of cytokines in inflammation and disease
    • Ouyang W, Rutz S, Crellin NK, Valdez PA, Hymowitz SG. 2011. Regulation and functions of the IL-10 family of cytokines in inflammation and disease. Annu Rev Immunol 29: 71–109.
    • (2011) Annu Rev Immunol , vol.29 , pp. 71-109
    • Ouyang, W.1    Rutz, S.2    Crellin, N.K.3    Valdez, P.A.4    Hymowitz, S.G.5
  • 163
    • 2342458559 scopus 로고    scopus 로고
    • Hydrodynamic gene delivery of interleukin-22 protects the mouse liver from concanavalin A-, carbon tetrachloride-, and Fas ligand-induced injury via activation of STAT3
    • Pan H, Hong F, Radaeva S, Gao B. 2004. Hydrodynamic gene delivery of interleukin-22 protects the mouse liver from concanavalin A-, carbon tetrachloride-, and Fas ligand-induced injury via activation of STAT3. Cell Mol Immunol 1: 43–49.
    • (2004) Cell Mol Immunol , vol.1 , pp. 43-49
    • Pan, H.1    Hong, F.2    Radaeva, S.3    Gao, B.4
  • 164
    • 79955776494 scopus 로고    scopus 로고
    • In vivo consequences of liver-specific interleukin-22 expression: Implications for human liver disease progression
    • Park O, Wang H, Weng H, Feigenbaum L, Li H, Yin S, Ki SH, Yoo SH, Dooley S, Wang FS, et al. 2011. In vivo consequences of liver-specific interleukin-22 expression: Implications for human liver disease progression. Hepatology 54: 252–261.
    • (2011) Hepatology , vol.54 , pp. 252-261
    • Park, O.1    Wang, H.2    Weng, H.3    Feigenbaum, L.4    Li, H.5    Yin, S.6    Ki, S.H.7    Yoo, S.H.8    Dooley, S.9    Wang, F.S.10
  • 171
    • 2342462460 scopus 로고    scopus 로고
    • Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation
    • Radaeva S, Sun R, Pan HN, Hong F, Gao B. 2004. Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation. Hepatology 39: 1332–1342.
    • (2004) Hepatology , vol.39 , pp. 1332-1342
    • Radaeva, S.1    Sun, R.2    Pan, H.N.3    Hong, F.4    Gao, B.5
  • 173
    • 0346364791 scopus 로고    scopus 로고
    • Epidermal overexpression of interleukin-19 and-20 mRNA in psoriatic skin disap-disap-pears after short-term treatment with cyclosporine a or calcipotriol
    • pears
    • Rømer J, Hasselager E, Nørby PL, Steiniche T, Thorn Clausen J, Kragballe K. 2003. Epidermal overexpression of interleukin-19 and-20 mRNA in psoriatic skin disap-disap-pears after short-term treatment with cyclosporine a or calcipotriol. J Invest Dermatol 121: 1306–1311. pears
    • (2003) J Invest Dermatol , vol.121 , pp. 1306-1311
    • Rømer, J.1    Hasselager, E.2    Nørby, P.L.3    Steiniche, T.4    Thorn Clausen, J.5    Kragballe, K.6
  • 176
    • 0029103042 scopus 로고
    • Long-term cultured CD40-activated B lymphocytes differentiate into plasma cells in response to IL-10 but not IL-4
    • Rousset F, Peyrol S, Garcia E, Vezzio N, Andujar M, Gri-maud JA, Banchereau J. 1995. Long-term cultured CD40-activated B lymphocytes differentiate into plasma cells in response to IL-10 but not IL-4. Int Immunol 7: 1243– 1253.
    • (1995) Int Immunol , vol.7 , pp. 1243-1253
    • Rousset, F.1    Peyrol, S.2    Garcia, E.3    Vezzio, N.4    Andujar, M.5    Gri-Maud, J.A.6    Banchereau, J.7
  • 178
    • 80053614883 scopus 로고    scopus 로고
    • Regulation of interleukin-10 and interleukin-22 expression in T helper cells
    • Rutz S, Ouyang W. 2011. Regulation of interleukin-10 and interleukin-22 expression in T helper cells. Curr Opin Immunol 23: 605–612.
    • (2011) Curr Opin Immunol , vol.23 , pp. 605-612
    • Rutz, S.1    Ouyang, W.2
  • 179
    • 84991643976 scopus 로고    scopus 로고
    • Regulation of interleukin-10 expression
    • Rutz S, Ouyang W. 2016. Regulation of interleukin-10 expression. Adv Exp Med Biol 941: 89–116.
    • (2016) Adv Exp Med Biol , vol.941 , pp. 89-116
    • Rutz, S.1    Ouyang, W.2
  • 181
    • 84873688049 scopus 로고    scopus 로고
    • IL-22, not simply a Th17 cytokine
    • Rutz S, Eidenschenk C, Ouyang W. 2013. IL-22, not simply a Th17 cytokine. Immunol Rev 252: 116–132.
    • (2013) Immunol Rev , vol.252 , pp. 116-132
    • Rutz, S.1    Eidenschenk, C.2    Ouyang, W.3
  • 182
    • 84922479625 scopus 로고    scopus 로고
    • The IL-20 subfamily of cytokines—From host defence to tissue homeostasis
    • Rutz S, Wang X, Ouyang W. 2014. The IL-20 subfamily of cytokines—From host defence to tissue homeostasis. Nat Rev Immunol 14: 783–795.
    • (2014) Nat Rev Immunol , vol.14 , pp. 783-795
    • Rutz, S.1    Wang, X.2    Ouyang, W.3
  • 183
    • 33846940253 scopus 로고    scopus 로고
    • The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis
    • Sa SM, Valdez PA, Wu J, Jung K, Zhong F, Hall L, Kasman I, Winer J, Modrusan Z, Danilenko DM, et al. 2007. The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis. J Immunol 178: 2229–2240.
    • (2007) J Immunol , vol.178 , pp. 2229-2240
    • Sa, S.M.1    Valdez, P.A.2    Wu, J.3    Jung, K.4    Zhong, F.5    Hall, L.6    Kasman, I.7    Winer, J.8    Modrusan, Z.9    Danilenko, D.M.10
  • 184
    • 84891702406 scopus 로고    scopus 로고
    • Therapeutic opportunities of the IL-22-IL-22R1 system
    • Sabat R, Ouyang W, Wolk K. 2013. Therapeutic opportunities of the IL-22-IL-22R1 system. Nat Rev Drug Discov 13: 21–38.
    • (2013) Nat Rev Drug Discov , vol.13 , pp. 21-38
    • Sabat, R.1    Ouyang, W.2    Wolk, K.3
  • 187
    • 53049091561 scopus 로고    scopus 로고
    • A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn’s disease
    • Sandborn WJ, Feagan BG, Fedorak RN, Scherl E, Fleisher MR, Katz S, Johanns J, Blank M, Rutgeerts P, Ustekinumab Crohn’s Disease Study. 2008. A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn’s disease. Gastroenterology 135: 1130–1141.
    • (2008) Gastroenterology , vol.135 , pp. 1130-1141
    • Sandborn, W.J.1    Feagan, B.G.2    Fedorak, R.N.3    Scherl, E.4    Fleisher, M.R.5    Katz, S.6    Johanns, J.7    Blank, M.8    Rutgeerts, P.9
  • 188
    • 77649184739 scopus 로고    scopus 로고
    • The regulation of IL-10 production by immune cells
    • Saraiva M, O’Garra A. 2010. The regulation of IL-10 production by immune cells. Nat Rev Immunol 10: 170–181.
    • (2010) Nat Rev Immunol , vol.10 , pp. 170-181
    • Saraiva, M.1    O’Garra, A.2
  • 191
    • 84930177232 scopus 로고    scopus 로고
    • Interleukin-10 paradox: A potent immunoregulatory cytokine that has been difficult to harness for immunotherapy
    • Saxena A, Khosraviani S, Noel S, Mohan D, Donner T, Hamad ARA. 2015. Interleukin-10 paradox: A potent immunoregulatory cytokine that has been difficult to harness for immunotherapy. Cytokine 74: 27–34.
    • (2015) Cytokine , vol.74 , pp. 27-34
    • Saxena, A.1    Khosraviani, S.2    Noel, S.3    Mohan, D.4    Donner, T.5    Hamad, A.R.A.6
  • 193
    • 25444492676 scopus 로고    scopus 로고
    • IL-12 family members: Differential kinetics of their TLR4-mediated induction by Salmonella enteritidis and the impact of IL-10 in bone marrow-derived macrophages
    • Schuetze N, Schoeneberger S, Mueller U, Freudenberg MA, Alber G, Straubinger RK. 2005. IL-12 family members: Differential kinetics of their TLR4-mediated induction by Salmonella enteritidis and the impact of IL-10 in bone marrow-derived macrophages. Int Immunol 17: 649–659.
    • (2005) Int Immunol , vol.17 , pp. 649-659
    • Schuetze, N.1    Schoeneberger, S.2    Mueller, U.3    Freudenberg, M.A.4    Alber, G.5    Straubinger, R.K.6
  • 194
    • 75649113035 scopus 로고    scopus 로고
    • Preclinical characterization of DEKAVIL (F8-IL10), a novel clinical-stage immunocyto-kine which inhibits the progression of collagen-induced arthritis
    • Schwager K, Kaspar M, Bootz F, Marcolongo R, Paresce E, Neri D, Trachsel E. 2009. Preclinical characterization of DEKAVIL (F8-IL10), a novel clinical-stage immunocyto-kine which inhibits the progression of collagen-induced arthritis. Arthritis Res Ther 11: R142.
    • (2009) Arthritis Res Ther , vol.11 , pp. R142
    • Schwager, K.1    Kaspar, M.2    Bootz, F.3    Marcolongo, R.4    Paresce, E.5    Neri, D.6    Trachsel, E.7
  • 195
    • 80051947187 scopus 로고    scopus 로고
    • The antibody-mediated targeted delivery of interleukin-10 inhibits endometriosis in a syngeneic mouse model
    • Schwager K, Bootz F, Imesch P, Kaspar M, Trachsel E, Neri D. 2011. The antibody-mediated targeted delivery of interleukin-10 inhibits endometriosis in a syngeneic mouse model. Hum Reprod 26: 2344–2352.
    • (2011) Hum Reprod , vol.26 , pp. 2344-2352
    • Schwager, K.1    Bootz, F.2    Imesch, P.3    Kaspar, M.4    Trachsel, E.5    Neri, D.6
  • 196
    • 0032412057 scopus 로고    scopus 로고
    • Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice
    • Sellon RK, Tonkonogy S, Schultz M, Dieleman LA, Grenther W, Balish E, Rennick DM, Sartor RB. 1998. Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice. Infect Immun 66: 5224–5231.
    • (1998) Infect Immun , vol.66 , pp. 5224-5231
    • Sellon, R.K.1    Tonkonogy, S.2    Schultz, M.3    Dieleman, L.A.4    Grenther, W.5    Balish, E.6    Rennick, D.M.7    Sartor, R.B.8
  • 197
    • 84929849291 scopus 로고    scopus 로고
    • Efficacy and safety of anti-interleukin-20 monoclonal antibody in patients with rheumatoid arthritis: A randomized phase IIa trial
    • Šenolt L, Leszczynski P, Dokoupilová E, Göthberg M, Valencia X, Hansen BB, Cañete JD. 2015. Efficacy and safety of anti-interleukin-20 monoclonal antibody in patients with rheumatoid arthritis: A randomized phase IIa trial. Arthritis Rheumatol 67: 1438–1448.
    • (2015) Arthritis Rheumatol , vol.67 , pp. 1438-1448
    • Šenolt, L.1    Leszczynski, P.2    Dokoupilová, E.3    Göthberg, M.4    Valencia, X.5    Hansen, B.B.6    Cañete, J.D.7
  • 198
    • 84883577100 scopus 로고    scopus 로고
    • The first decade of biologic TNF antagonists in clinical practice: Lessons learned, unresolved issues and future directions
    • Sfikakis PP. 2010. The first decade of biologic TNF antagonists in clinical practice: Lessons learned, unresolved issues and future directions. Curr Dir Autoimmun 11: 180– 210.
    • (2010) Curr Dir Autoimmun , vol.11 , pp. 180-210
    • Sfikakis, P.P.1
  • 199
    • 84928774156 scopus 로고    scopus 로고
    • The future of immune checkpoint therapy
    • Sharma P, Allison JP. 2015. The future of immune checkpoint therapy. Science 348: 56–61.
    • (2015) Science , vol.348 , pp. 56-61
    • Sharma, P.1    Allison, J.P.2
  • 200
    • 85012158583 scopus 로고    scopus 로고
    • Primary, adaptive, and acquired resistance to cancer immunotherapy
    • Sharma P, Hu-Lieskovan S, Wargo JA, Ribas A. 2017. Primary, adaptive, and acquired resistance to cancer immunotherapy. Cell 168: 707–723.
    • (2017) Cell , vol.168 , pp. 707-723
    • Sharma, P.1    Hu-Lieskovan, S.2    Wargo, J.A.3    Ribas, A.4
  • 201
    • 66449133523 scopus 로고    scopus 로고
    • Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis
    • Shen H, Goodall JC, Hill Gaston JS. 2009. Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis. Arthritis Rheum 60: 1647–1656.
    • (2009) Arthritis Rheum , vol.60 , pp. 1647-1656
    • Shen, H.1    Goodall, J.C.2    Hill Gaston, J.S.3
  • 204
    • 0033517356 scopus 로고    scopus 로고
    • Cutaneous wound healing
    • Singer AJ, Clark RA. 1999. Cutaneous wound healing. N Engl J Med 341: 738–746.
    • (1999) N Engl J Med , vol.341 , pp. 738-746
    • Singer, A.J.1    Clark, R.A.2
  • 205
    • 42949160129 scopus 로고    scopus 로고
    • IFN-lambda (IFN-λ) is expressed in a tissue-dependent fashion and primarily acts on epithelial cells in vivo
    • Sommereyns C, Paul S, Staeheli P, Michiels T. 2008. IFN-lambda (IFN-λ) is expressed in a tissue-dependent fashion and primarily acts on epithelial cells in vivo. PloS Pathog 4: e1000017.
    • (2008) Plos Pathog , vol.4
    • Sommereyns, C.1    Paul, S.2    Staeheli, P.3    Michiels, T.4
  • 206
    • 79955030498 scopus 로고    scopus 로고
    • Border patrol: Regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22
    • Sonnenberg GF, Fouser LA, Artis D. 2011. Border patrol: Regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22. Nat Immunol 12: 383– 390.
    • (2011) Nat Immunol , vol.12 , pp. 383-390
    • Sonnenberg, G.F.1    Fouser, L.A.2    Artis, D.3
  • 208
    • 77955886364 scopus 로고    scopus 로고
    • Interferon-λ as a potential therapeutic agent in cancer treatment
    • Steen HC, Gamero AM. 2010. Interferon-λ as a potential therapeutic agent in cancer treatment. J Interferon Cytokine Res 30: 597–602.
    • (2010) J Interferon Cytokine Res , vol.30 , pp. 597-602
    • Steen, H.C.1    Gamero, A.M.2
  • 214
    • 0032564357 scopus 로고    scopus 로고
    • The cancer growth suppressor gene mda-7 selectively induces apoptosis in human breast cancer cells and inhibits tumor growth in nude mice
    • Su ZZ, Madireddi MT, Lin JJ, Young CS, Kitada S, Reed JC, Goldstein NI, Fisher PB. 1998. The cancer growth suppressor gene mda-7 selectively induces apoptosis in human breast cancer cells and inhibits tumor growth in nude mice. Proc Natl Acad Sci 95: 14400–14405.
    • (1998) Proc Natl Acad Sci , vol.95 , pp. 14400-14405
    • Su, Z.Z.1    Madireddi, M.T.2    Lin, J.J.3    Young, C.S.4    Kitada, S.5    Reed, J.C.6    Goldstein, N.I.7    Fisher, P.B.8
  • 216
    • 84877828212 scopus 로고    scopus 로고
    • Interleukin (IL)-19 promoted skin wound healing by increasing fibroblast keratinocyte growth factor expression
    • Sun DP, Yeh CH, So E, Wang LY, Wei TS, Chang MS, Hsing CH. 2013. Interleukin (IL)-19 promoted skin wound healing by increasing fibroblast keratinocyte growth factor expression. Cytokine 62: 360–368.
    • (2013) Cytokine , vol.62 , pp. 360-368
    • Sun, D.P.1    Yeh, C.H.2    So, E.3    Wang, L.Y.4    Wei, T.S.5    Chang, M.S.6    Hsing, C.H.7
  • 220
    • 84862777861 scopus 로고    scopus 로고
    • HCV infection induces a unique hepatic innate immune response associated with robust production of type III interferons
    • Thomas E, Gonzalez VD, Li Q, Modi AA, Chen W, Nou-reddin M, Rotman Y, Liang TJ. 2012. HCV infection induces a unique hepatic innate immune response associated with robust production of type III interferons. Gastroenterology 142: 978–988.
    • (2012) Gastroenterology , vol.142 , pp. 978-988
    • Thomas, E.1    Gonzalez, V.D.2    Li, Q.3    Modi, A.A.4    Chen, W.5    Nou-Reddin, M.6    Rotman, Y.7    Liang, T.J.8
  • 223
    • 19944384118 scopus 로고    scopus 로고
    • Intratumoral injection of INGN 241, a nonreplicat-ing adenovector expressing the melanoma-differentiation associated gene-7 (Mda-7/IL24): Biologic outcome in advanced cancer patients
    • Tong AW, Nemunaitis J, Su D, Zhang Y, Cunningham C, Senzer N, Netto G, Rich D, Mhashilkar A, Parker K, et al. 2005. Intratumoral injection of INGN 241, a nonreplicat-ing adenovector expressing the melanoma-differentiation associated gene-7 (mda-7/IL24): Biologic outcome in advanced cancer patients. Mol Ther 11: 160–172.
    • (2005) Mol Ther , vol.11 , pp. 160-172
    • Tong, A.W.1    Nemunaitis, J.2    Su, D.3    Zhang, Y.4    Cunningham, C.5    Senzer, N.6    Netto, G.7    Rich, D.8    Mhashilkar, A.9    Parker, K.10
  • 225
    • 84928062583 scopus 로고    scopus 로고
    • Immune checkpoint blockade: A common denominator approach to cancer therapy
    • Topalian SL, Drake CG, Pardoll DM. 2015. Immune checkpoint blockade: A common denominator approach to cancer therapy. Cancer Cell 27: 450–461.
    • (2015) Cancer Cell , vol.27 , pp. 450-461
    • Topalian, S.L.1    Drake, C.G.2    Pardoll, D.M.3
  • 226
    • 33847286913 scopus 로고    scopus 로고
    • Antibody-mediated delivery of IL-10 inhibits the progression of established collagen-induced arthritis
    • Trachsel E, Bootz F, Silacci M, Kaspar M, Kosmehl H, Neri D. 2007. Antibody-mediated delivery of IL-10 inhibits the progression of established collagen-induced arthritis. Arthritis Res Ther 9: R9.
    • (2007) Arthritis Res Ther , vol.9 , pp. R9
    • Trachsel, E.1    Bootz, F.2    Silacci, M.3    Kaspar, M.4    Kosmehl, H.5    Neri, D.6
  • 227
    • 34347259525 scopus 로고    scopus 로고
    • IL-28 and IL-29: Newcomers to the interferon family
    • Uzé G, Monneron D. 2007. IL-28 and IL-29: Newcomers to the interferon family. Biochimie 89: 729–734.
    • (2007) Biochimie , vol.89 , pp. 729-734
    • Uzé, G.1    Monneron, D.2
  • 228
    • 0030835754 scopus 로고    scopus 로고
    • Multiple doses of intravenous interleukin 10 in steroid-refractory Crohn’s disease
    • van Deventer SJ, Elson CO, Fedorak RN; Crohn’s Disease Study Group. 1997. Multiple doses of intravenous interleukin 10 in steroid-refractory Crohn’s disease. Gastroenterology 113: 383–389.
    • (1997) Gastroenterology , vol.113 , pp. 383-389
    • van Deventer, S.J.1    Elson, C.O.2    Fedorak, R.N.3
  • 229
    • 9644302458 scopus 로고    scopus 로고
    • Interleukin-10 in viral diseases and cancer: Exiting the labyrinth?
    • Vicari AP, Trinchieri G. 2004. Interleukin-10 in viral diseases and cancer: Exiting the labyrinth? Immunol Rev 202: 223–236.
    • (2004) Immunol Rev , vol.202 , pp. 223-236
    • Vicari, A.P.1    Trinchieri, G.2
  • 230
    • 80052301263 scopus 로고    scopus 로고
    • High fat diet induces formation of spontaneous liposarcoma in mouse adipose tissue with overexpression of interleukin 22
    • Wang Z, Yang L, Jiang Y, Ling ZQ, Li Z, Cheng Y, Huang H, Wang L, Pan Y, Wang Z, et al. 2011. High fat diet induces formation of spontaneous liposarcoma in mouse adipose tissue with overexpression of interleukin 22. PloS ONE 6: e23737.
    • (2011) Plos ONE , vol.6
    • Wang, Z.1    Yang, L.2    Jiang, Y.3    Ling, Z.Q.4    Li, Z.5    Cheng, Y.6    Huang, H.7    Wang, L.8    Pan, Y.9    Wang, Z.10
  • 232
    • 0030639030 scopus 로고    scopus 로고
    • Pathways for the regulation of macrophage iron metabolism by the anti-inflammatory cytokines IL-4 and IL-13
    • Weiss G, Bogdan C, Hentze MW. 1997. Pathways for the regulation of macrophage iron metabolism by the anti-inflammatory cytokines IL-4 and IL-13. J Immunol 158: 420–425.
    • (1997) J Immunol , vol.158 , pp. 420-425
    • Weiss, G.1    Bogdan, C.2    Hentze, M.W.3
  • 235
    • 19644366045 scopus 로고    scopus 로고
    • Clinical practice. Atopic dermatitis
    • Williams HC. 2005. Clinical practice. Atopic dermatitis. N Engl J Med 352: 2314–2324.
    • (2005) N Engl J Med , vol.352 , pp. 2314-2324
    • Williams, H.C.1
  • 237
    • 73849130903 scopus 로고    scopus 로고
    • Despite IFN-λ receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: Implications for therapeutic applications of these cytokines
    • Witte K, Gruetz G, Volk H-D, Looman AC, Asadullah K, Sterry W, Sabat R, Wolk K. 2009. Despite IFN-λ receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: Implications for therapeutic applications of these cytokines. Genes Immun 10: 702–714.
    • (2009) Genes Immun , vol.10 , pp. 702-714
    • Witte, K.1    Gruetz, G.2    Volk, H.-D.3    Looman, A.C.4    Asadullah, K.5    Sterry, W.6    Sabat, R.7    Wolk, K.8
  • 238
    • 0028346888 scopus 로고
    • Production of interleukin 10 by islet cells accelerates immune-mediated destruction of β cells in nonobese diabetic mice
    • Wogensen L, Lee MS, Sarvetnick N. 1994. Production of interleukin 10 by islet cells accelerates immune-mediated destruction of β cells in nonobese diabetic mice. J Exp Med 179: 1379–1384.
    • (1994) J Exp Med , vol.179 , pp. 1379-1384
    • Wogensen, L.1    Lee, M.S.2    Sarvetnick, N.3
  • 239
    • 33749983749 scopus 로고    scopus 로고
    • Interleukin-22: A novel T-and NK-cell derived cytokine that regulates the biology of tissue cells
    • Wolk K, Sabat R. 2006. Interleukin-22: A novel T-and NK-cell derived cytokine that regulates the biology of tissue cells. Cytokine Growth Factor Rev 17: 367–380.
    • (2006) Cytokine Growth Factor Rev , vol.17 , pp. 367-380
    • Wolk, K.1    Sabat, R.2
  • 240
    • 0036604122 scopus 로고    scopus 로고
    • Cutting edge: Immune cells as sources and targets of the IL-10 family members?
    • Wolk K, Kunz S, Asadullah K, Sabat R. 2002. Cutting edge: Immune cells as sources and targets of the IL-10 family members? J Immunol 168: 5397–5402.
    • (2002) J Immunol , vol.168 , pp. 5397-5402
    • Wolk, K.1    Kunz, S.2    Asadullah, K.3    Sabat, R.4
  • 242
    • 33646552450 scopus 로고    scopus 로고
    • IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: A potential role in psoriasis
    • Wolk K, Witte E, Wallace E, Döcke WD, Kunz S, Asadullah K, Volk HD, Sterry W, Sabat R. 2006. IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: A potential role in psoriasis. Eur J Immunol 36: 1309–1323.
    • (2006) Eur J Immunol , vol.36 , pp. 1309-1323
    • Wolk, K.1    Witte, E.2    Wallace, E.3    Döcke, W.D.4    Kunz, S.5    Asadullah, K.6    Volk, H.D.7    Sterry, W.8    Sabat, R.9
  • 245
    • 34547176642 scopus 로고    scopus 로고
    • Unravelling the pathogenesis of inflammatory bowel disease
    • Xavier RJ, Podolsky DK. 2007. Unravelling the pathogenesis of inflammatory bowel disease. Nature 448: 427–434.
    • (2007) Nature , vol.448 , pp. 427-434
    • Xavier, R.J.1    Podolsky, D.K.2
  • 246
    • 0034613201 scopus 로고    scopus 로고
    • Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2–4 and IL-22R
    • Xie MH, Aggarwal S, Ho WH, Foster J, Zhang Z, Stinson J, Wood WI, Goddard AD, Gurney AL. 2000. Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2–4 and IL-22R. J Biol Chem 275: 31335–31339.
    • (2000) J Biol Chem , vol.275 , pp. 31335-31339
    • Xie, M.H.1    Aggarwal, S.2    Ho, W.H.3    Foster, J.4    Zhang, Z.5    Stinson, J.6    Wood, W.I.7    Goddard, A.D.8    Gurney, A.L.9
  • 247
  • 249
    • 84877330590 scopus 로고    scopus 로고
    • Expression of interleukin-22/STAT3 signaling pathway in ulcerative colitis and related carcinogenesis
    • Yu LZ, Wang HY, Yang SP, Yuan ZP, Xu FY, Sun C, Shi RH. 2013. Expression of interleukin-22/STAT3 signaling pathway in ulcerative colitis and related carcinogenesis. World J Gastroenterol 19: 2638–2649.
    • (2013) World J Gastroenterol , vol.19 , pp. 2638-2649
    • Yu, L.Z.1    Wang, H.Y.2    Yang, S.P.3    Yuan, Z.P.4    Xu, F.Y.5    Sun, C.6    Shi, R.H.7
  • 250
    • 84908161000 scopus 로고    scopus 로고
    • Revisiting STAT3 signalling in cancer: New and unexpected biological functions
    • Yu H, Lee H, Herrmann A, Buettner R, Jove R. 2014. Revisiting STAT3 signalling in cancer: New and unexpected biological functions. Nat Rev Cancer 14: 736–746.
    • (2014) Nat Rev Cancer , vol.14 , pp. 736-746
    • Yu, H.1    Lee, H.2    Herrmann, A.3    Buettner, R.4    Jove, R.5
  • 251
    • 35348983341 scopus 로고    scopus 로고
    • Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation
    • Zenewicz LA, Yancopoulos GD, Valenzuela DM, Murphy AJ, Karow M, Flavell RA. 2007. Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation. Immunity 27: 647–659.
    • (2007) Immunity , vol.27 , pp. 647-659
    • Zenewicz, L.A.1    Yancopoulos, G.D.2    Valenzuela, D.M.3    Murphy, A.J.4    Karow, M.5    Flavell, R.A.6
  • 253
    • 84877839153 scopus 로고    scopus 로고
    • IL-22 deficiency alters colonic micro-biota to be transmissible and colitogenic
    • Zenewicz LA, Yin X, Wang G, Elinav E, Hao L, Zhao L, Flavell RA. 2013. IL-22 deficiency alters colonic micro-biota to be transmissible and colitogenic. J Immunol 190: 5306–5312.
    • (2013) J Immunol , vol.190 , pp. 5306-5312
    • Zenewicz, L.A.1    Yin, X.2    Wang, G.3    Elinav, E.4    Hao, L.5    Zhao, L.6    Flavell, R.A.7
  • 255
    • 84859237495 scopus 로고    scopus 로고
    • Increased frequencies of Th22 cells as well as Th17 cells in the peripheral blood of patients with ankylosing spondylitis and rheumatoid arthritis
    • Zhang L, Li Y-G, Li Y-H, Qi L, Liu X-G, Yuan C-Z, Hu N-W, Ma D-X, Li Z-F, Yang Q, et al. 2012. Increased frequencies of Th22 cells as well as Th17 cells in the peripheral blood of patients with ankylosing spondylitis and rheumatoid arthritis. PloS ONE 7: e31000.
    • (2012) Plos ONE , vol.7
    • Zhang, L.1    Li, Y.-G.2    Li, Y.-H.3    Qi, L.4    Liu, X.-G.5    Yuan, C.-Z.6    Hu, N.-W.7    Ma, D.-X.8    Li, Z.-F.9    Yang, Q.10
  • 256


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.