A pathogenic role for T cell-derived IL-22BP in inflammatory bowel disease

Science

Volumn 354, Issue 6310, 2016, Pages 358-362

  Pelczar, Penelope ^a   Witkowski, Mario ^a,b   Perez, Laura Garcia ^a   Kempski, Jan ^a   Hammel, Anna G ^a   Brockmann, Leonie ^a   Kleinschmidt, Dörte ^a   Wende, Sandra ^a   Haueis, Cathleen ^a   Bedke, Tanja ^a   Witkowski, Marco ^c   Krasemann, Susanne ^a   Steurer, Stefan ^a   Booth, Carmen J ^d   Busch, Philipp ^a   König, Alexandra ^a,f   Rauch, Ursula ^c   Benten, Daniel ^a   Izbicki, Jakob R ^a   Rösch, Thomas ^a   Lohse, Ansgar W ^a   Strowig, Till ^e   Gagliani, Nicola ^a   Flavell, Richard A ^d   Huber, Samuel ^a   more..

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^f Klinikum Wilhelmshaven   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADALIMUMAB; BIOLOGICAL MARKER; CARRIER PROTEINS AND BINDING PROTEINS; CD45RB ANTIGEN; GAMMA INTERFERON; IMMUNOMODULATING AGENT; INFLIXIMAB; INHIBITOR PROTEIN; INTERLEUKIN 17; INTERLEUKIN 18; INTERLEUKIN 22; INTERLEUKIN 22 BINDING PROTEIN; INTERLEUKIN 22 RECEPTOR 1; INTERLEUKIN 23; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN RECEPTOR; MESSENGER RNA; PROTEIN; RAG1 PROTEIN; RETINOID RELATED ORPHAN RECEPTOR GAMMA; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET; UNCLASSIFIED DRUG; ANTIBODY; INTERLEUKIN-22 RECEPTOR; TUMOR NECROSIS FACTOR;

ANTIBODY; CELLS AND CELL COMPONENTS; DIGESTIVE SYSTEM DISORDER; GENE EXPRESSION; INHIBITOR; MUCUS; PATHOGENICITY; PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CROHN DISEASE; CYTOKINE PRODUCTION; DRUG TARGETING; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPATHOGENESIS; INFLAMMATORY BOWEL DISEASE; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ULCERATIVE COLITIS; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; DISEASE MODEL; IMMUNOLOGY; IMMUNOTHERAPY; INFLAMMATORY BOWEL DISEASES; INTESTINE MUCOSA; MUCOSAL IMMUNITY;

ANIMALS; ANTIBODIES; CD4-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; HUMANS; IMMUNITY, MUCOSAL; IMMUNOTHERAPY; INFLAMMATORY BOWEL DISEASES; INTESTINAL MUCOSA; MICE; RECEPTORS, INTERLEUKIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84992028009     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aah5903     Document Type: Article

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