Interleukin (IL)-19 promoted skin wound healing by increasing fibroblast keratinocyte growth factor expression

Cytokine

Volumn 62, Issue 3, 2013, Pages 360-368

  Sun, Ding Ping ^a   Yeh, Ching Hua ^c   So, Edmund ^e,f   Wang, Li Yun ^a   Wei, Tsui Shan ^c   Chang, Ming Shi ^d   Hsing, Chung Hsi ^a,b  

^a CHI MEI MEDICAL CENTER   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c CHANG JUNG CHRISTIAN UNIVERSITY   (Taiwan)

^d NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^e CHINA MEDICAL UNIVERSITY   (Taiwan)

^f CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Cytokines; Interleukin 19; Keratinocyte growth factor; Wound healing

Indexed keywords

INTERLEUKIN 19; KERATINOCYTE GROWTH FACTOR; CULTURE MEDIUM; IL19 PROTEIN, HUMAN; IL19 PROTEIN, MOUSE; INTERLEUKIN 10; INTERLEUKIN 20; INTERLEUKIN DERIVATIVE; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTICLE; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; EPITHELIZATION; FIBROBLAST; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOREGULATION; IN VITRO STUDY; IN VIVO STUDY; KERATINOCYTE; MORPHOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WOUND HEALING; ANIMAL; BAGG ALBINO MOUSE; CELL LINE; CELL MOTION; CULTURE MEDIUM; DRUG EFFECTS; GENETICS; METABOLISM; PATHOLOGY; PHARMACOLOGY; PHOSPHORYLATION; SKIN;

MUS;

ANIMALS; CELL LINE; CELL MOVEMENT; CELL PROLIFERATION; CULTURE MEDIA; FIBROBLAST GROWTH FACTOR 7; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-10; INTERLEUKINS; KERATINOCYTES; MICE; MICE, INBRED BALB C; PHOSPHORYLATION; RNA, MESSENGER; SIGNAL TRANSDUCTION; SKIN; WOUND HEALING;

EID: 84877828212     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2013.03.017     Document Type: Article

References (36)

1. Woodley D.T., O'Keefe E.J., Prunieras M. Cutaneous wound healing: a model for cell-matrix interactions. J Am Acad Dermatol 1985, 12:420-433.
2. Martin P. Wound healing - aiming for perfect skin regeneration. Science 1997, 276:75-81.
3. Midwood K.S., Williams L.V., Schwarzbauer J.E. Tissue repair and the dynamics of the extracellular matrix. Int J Biochem Cell Biol 2004, 36:1031-1037.
4. Martin P., Hopkinson-Woolley J., McCluskey J. Growth factors and cutaneous wound repair. Prog Growth Factor Res 1992, 4:25-44.
5. Werner S. Keratinocyte growth factor: a unique player in epithelial repair processes. Cytokine Growth Factor Rev 1998, 9:153-165.
6. Werner S., Peters K.G., Longaker M.T., Fuller-Pace F., Banda M.J., Williams L.T. Large induction of keratinocyte growth factor expression in the dermis during wound healing. Proc Natl Acad Sci USA 1992, 89:6896-6900.
7. Beer H.D., Gassmann M.G., Munz B., Steiling H., Engelhardt F., Bleuel K., et al. Expression and function of keratinocyte growth factor and activin in skin morphogenesis and cutaneous wound repair. J Invest Dermatol Sympos Proc 2000, 5:34-39. [the Society for Investigative Dermatology, Inc [and] European Society for Dermatological Research].
8. Werner S., Smola H., Liao X., Longaker M.T., Krieg T., Hofschneider P.H., et al. The function of KGF in morphogenesis of epithelium and reepithelialization of wounds. Science 1994, 266:819-822.
9. Commins S., Steinke J.W., Borish L. The extended IL-10 superfamily: IL-10, IL-19, IL-20, IL-22, IL-24, IL-26, IL-28, and IL-29. J Allergy Clin Immunol 2008, 121:1108-1111.
10. Sabat R., Wallace E., Endesfelder S., Wolk K. IL-19 and IL-20: two novel cytokines with importance in inflammatory diseases. Expert Opin Therap Target 2007, 11:601-612.
11. Gallagher G. Interleukin-19: multiple roles in immune regulation and disease. Cytokine Growth Factor Rev 2010, 21:345-352.
12. Hsing C.H., Li H.H., Hsu Y.H., Ho C.L., Chuang S.S., Lan K.M., et al. The distribution of interleukin-19 in healthy and neoplastic tissue. Cytokine 2008, 44:221-228.
13. Gallagher G., Eskdale J., Jordan W., Peat J., Campbell J., Boniotto M., et al. Human interleukin-19 and its receptor: a potential role in the induction of Th2 responses. Int Immunopharmacol. 2004, 4:615-626.
14. Hsing C.H., Hsu C.C., Chen W.Y., Chang L.Y., Hwang J.C., Chang M.S. Expression of IL-19 correlates with Th2 cytokines in uraemic patients. Nephrol Dial Transplant 2007, 22:2230-2238. [official publication of the European Dialysis and Transplant Association - European Renal Association].
15. Hsing C.H., Hsieh M.Y., Chen W.Y., Cheung So E., Cheng B.C., Chang M.S. Induction of interleukin-19 and interleukin-22 after cardiac surgery with cardiopulmonary bypass. Ann Thorac Surg 2006, 81:2196-2201.
16. Hsing C.H., Chiu C.J., Chang L.Y., Hsu C.C., Chang M.S. IL-19 is involved in the pathogenesis of endotoxic shock. Shock 2008, 29:7-15.
17. Hoffman C., Park S.H., Daley E., Emson C., Louten J., Sisco M., et al. Interleukin-19: a constituent of the regulome that controls antigen presenting cells in the lungs and airway responses to microbial products. PLoS ONE 2011, 6:e27629.
18. Wahl C., Muller W., Leithauser F., Adler G., Oswald F., Reimann J., et al. IL-20 receptor 2 signaling down-regulates antigen-specific T cell responses. J Immunol 2009, 182:802-810.
19. Yeh C.H., Cheng B.C., Hsu C.C., Chen H.W., Wang J.J., Chang M.S., et al. Induced interleukin-19 contributes to cell-mediated immunosuppression in patients undergoing coronary artery bypass grafting with cardiopulmonary bypass. Ann Thorac Surg 2011, 92:1252-1259.
20. Hsing C.H., Cheng H.C., Hsu Y.H., Chan C.H., Yeh C.H., Li C.F., et al. Upregulated IL-19 in breast cancer promotes tumor progression and affects clinical outcome. Clin Cancer Res 2012, 18:713-725. [an official journal of the American Association for Cancer Research].
21. Hsu Y.H., Hsieh P.P., Chang M.S. Interleukin-19 blockade attenuates collagen-induced arthritis in rats. Rheumatology (Oxford) 2012, 51:434-442.
22. Azuma Y.T., Matsuo Y., Nakajima H., Yancopoulos G.D., Valenzuela D.M., Murphy A.J., et al. Interleukin-19 is a negative regulator of innate immunity and critical for colonic protection. J Pharmacol Sci 2011, 115:105-111.
23. Jain S., Gabunia K., Kelemen S.E., Panetti T.S., Autieri M.V. The anti-inflammatory cytokine interleukin 19 is expressed by and angiogenic for human endothelial cells. Arterioscler Thromb Vasc Biol 2011, 31:167-175.
24. Wang F., Smith N., Maier L., Xia W., Hammerberg C., Chubb H., et al. Etanercept suppresses regenerative hyperplasia in psoriasis by acutely downregulating epidermal expression of IL-19, IL-20 and IL-24. Br J Dermatol 2012.
25. Li H.H., Lin Y.C., Chen P.J., Hsiao C.H., Lee J.Y., Chen W.C., et al. Interleukin-19 upregulates keratinocyte growth factor and is associated with psoriasis. Br J Dermatol 2005, 153:591-595.
26. Kwon Y.B., Kim H.W., Roh D.H., Yoon S.Y., Baek R.M., Kim J.Y., et al. Topical application of epidermal growth factor accelerates wound healing by myofibroblast proliferation and collagen synthesis in rat. J Vet Sci 2006, 7:105-109.
27. Liao S.C., Cheng Y.C., Wang Y.C., Wang C.W., Yang S.M., Yu C.K., et al. IL-19 induced Th2 cytokines and was up-regulated in asthma patients. J Immunol 2004, 173:6712-6718.
28. Brauchle M., Angermeyer K., Hubner G., Werner S. Large induction of keratinocyte growth factor expression by serum growth factors and pro-inflammatory cytokines in cultured fibroblasts. Oncogene 1994, 9:3199-3204.
29. Chedid M., Rubin J.S., Csaky K.G., Aaronson S.A. Regulation of keratinocyte growth factor gene expression by interleukin 1. J Biol Chem 1994, 269:10753-10757.
30. Quayle J.A., Adams S., Bucknall R.C., Edwards S.W. Cytokine expression by inflammatory neutrophils. FEMS Immunol Med Microbiol 1994, 8:233-239.
31. Hubner G., Brauchle M., Smola H., Madlener M., Fassler R., Werner S. Differential regulation of pro-inflammatory cytokines during wound healing in normal and glucocorticoid-treated mice. Cytokine 1996, 8:548-556.
32. McFarland-Mancini M.M., Funk H.M., Paluch A.M., Zhou M., Giridhar P.V., Mercer C.A., et al. Differences in wound healing in mice with deficiency of IL-6 versus IL-6 receptor. J Immunol 2010, 184:7219-7228.
33. Hsing C.H., Ho C.L., Chang L.Y., Lee Y.L., Chuang S.S., Chang M.S. Tissue microarray analysis of interleukin-20 expression. Cytokine 2006, 35:44-52.
34. Logsdon N.J., Deshpande A., Harris B.D., Rajashankar K.R., Walter M.R. Structural basis for receptor sharing and activation by interleukin-20 receptor-2 (IL-20R2) binding cytokines. Proc Natl Acad Sci USA 2012, 109:12704-12709.
35. Gabunia K., Jain S., England R.N., Autieri M.V. Anti-inflammatory cytokine interleukin-19 inhibits smooth muscle cell migration and activation of cytoskeletal regulators of VSMC motility. Am J Physiol Cell Physiol 2011, 300:C896-C906.
36. Hsing C.H., Cheng H.C., Hsu Y.H., Chan C.H., Yeh C.H., Li C.F., et al. Upregulated IL-19 in breast cancer promotes tumor progression and affects clinical outcome. Clin Cancer Res 2011.