Interleukin 22 serum levels are associated with radiographic progression in rheumatoid arthritis

Annals of the Rheumatic Diseases

Volumn 70, Issue 8, 2011, Pages 1453-1457

  Leipe, Jan ^a   Schramm, Markus A ^a   Grunke, Mathias ^a   Baeuerle, Michael ^a   Dechant, Claudia ^a   Nigg, Axel P ^a   Witt, Matthias N ^a   Vielhauer, Volker ^a   Reindl, Christiane S ^a   Schulze Koops, Hendrik ^a   Skapenko, Alla ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC CITRULLINATED PEPTIDE ANTIBODY; GLUCOCORTICOID; INTERLEUKIN 17; INTERLEUKIN 22; METHOTREXATE; RHEUMATOID FACTOR; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR INHIBITOR;

ADULT; ARTICLE; BONE EROSION; CD4+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ACTIVITY; DISEASE COURSE; DRUG DOSE ESCALATION; FEMALE; FLOW CYTOMETRY; FOLLOW UP; HUMAN; HUMAN CELL; JOINT RADIOGRAPHY; MALE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; T LYMPHOCYTE;

ADULT; AGED; ARTHRITIS, RHEUMATOID; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; DISEASE PROGRESSION; FEMALE; FOLLOW-UP STUDIES; HUMANS; INTERLEUKINS; MALE; MIDDLE AGED; T-LYMPHOCYTE SUBSETS;

EID: 79959811817     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/ard.2011.152074     Document Type: Article

References (23)

1. Skapenko A, Leipe J, Lipsky PE, et al. The role of the T cell in autoimmune inflammation. Arthritis Res Ther 2005;7(Suppl 2):S4-14.
2. Geboes L, Dumoutier L, Kelchtermans H, et al. Proinflammatory role of the Th17 cytokine interleukin-22 in collagen-induced arthritis in C57BL/6 mice. Arthritis Rheum 2009;60:390-5.
3. Ikeuchi H, Kuroiwa T, Hiramatsu N, et al. Expression of interleukin-22 in rheumatoid arthritis: potential role as a proinflammatory cytokine. Arthritis Rheum 2005;52:1037-46. (Pubitemid 40530109)
4. Cascão R, Moura RA, Perpétuo I, et al. Identification of a cytokine network sustaining neutrophil and Th17 activation in untreated early rheumatoid arthritis. Arthritis Res Ther 2010;12:R196.
5. Koch AE, Kunkel SL, Harlow LA, et al. Enhanced production of monocyte chemoattractant protein-1 in rheumatoid arthritis. J Clin Invest 1992;90:772-9.
6. Wolk K, Kunz S, Asadullah K, et al. Cutting edge: immune cells as sources and targets of the IL-10 family members? J Immunol 2002;168:5397-402.
7. Lubberts E. Th17 cytokines and arthritis. Semin Immunopathol 2010;32:43-53.
8. Liang SC, Tan XY, Luxenberg DP, et al. Interleukin (IL)-22 and IL-17 are co-expressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J Exp Med 2006;203:2271-9. (Pubitemid 44498362)
9. Duhen T, Geiger R, Jarrossay D, et al. Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. Nat Immunol 2009;10:857-63.
10. Trifari S, Kaplan CD, Tran EH, et al. Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells. Nat Immunol 2009;10:864-71.
11. Acosta-Rodriguez EV, Rivino L, Geginat J, et al. Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells. Nat Immunol 2007;8:639-46. (Pubitemid 46785128)
12. Arnett FC, Edworthy SM, Bloch DA, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
13. Leipe J, Grunke M, Dechant C, et al. Role of Th17 cells in human autoimmune arthritis. Arthritis Rheum 2010;62:2876-85.
14. Nistala K, Moncrieffe H, Newton KR, et al. Interleukin-17-producing T cells are enriched in the joints of children with arthritis, but have a reciprocal relationship to regulatory T cell numbers. Arthritis Rheum 2008;58:875-87. (Pubitemid 351364887)
15. Colin EM, Asmawidjaja PS, van Hamburg JP, et al. 1,25-dihydroxyvitamin D3 modulates Th17 polarization and interleukin-22 expression by memory T cells from patients with early rheumatoid arthritis. Arthritis Rheum 2010;62:132-42.
16. Shen H, Goodall JC, Hill Gaston JS. Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis. Arthritis Rheum 2009;60:1647-56.
17. Skapenko A, Wendler J, Lipsky PE, et al. Altered memory T cell differentiation in patients with early rheumatoid arthritis. J Immunol 1999;163:491-9. (Pubitemid 29295878)
18. Wolk K, Witte E, Wallace E, et al. IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis. Eur J Immunol 2006;36:1309-23.
19. Ma HL, Liang S, Li J, et al. IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation. J Clin Invest 2008;118:597-607. (Pubitemid 351206549)
20. Wolk K, Witte E, Hoffmann U, et al. IL-22 induces lipopolysaccharide- binding protein in hepatocytes: a potential systemic role of IL-22 in Crohn's disease. J Immunol 2007;178:5973-81. (Pubitemid 46674395)
21. Eyerich S, Eyerich K, Cavani A, et al. IL-17 and IL-22: siblings, not twins. Trends Immunol 2010;31:354-61.
22. Di Stefano A, Caramori G, Gnemmi I, et al. Thelper type 17-related cytokine expression is increased in the bronchial mucosa of stable chronic obstructive pulmonary disease patients. Clin Exp Immunol 2009;157:316-24.
23. Skapenko A, Prots I, Schulze-Koops H. Prognostic factors in rheumatoid arthritis in the era of biologic agents. Nat Rev Rheumatol 2009;5:491-6.