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Volumn 130, Issue 6, 2012, Pages 1344-1354

Progressive activation of TH2/TH22 cytokines and selective epidermal proteins characterizes acute and chronic atopic dermatitis

Author keywords

acute; Atopic dermatitis; chronic; IL 22; S100A7; S100A8; S100A9; T H17; TH2; TH22; terminal differentiation

Indexed keywords

CALGRANULIN A; CALGRANULIN B; CYTOKINE; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 22; INTERLEUKIN 31; INTERLEUKIN 4; PSORIASIN; TRANSCRIPTOME;

EID: 84870294267     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2012.07.012     Document Type: Article
Times cited : (728)

References (68)
  • 1
    • 37749025593 scopus 로고    scopus 로고
    • Atopic dermatitis
    • T. Bieber Atopic dermatitis N Engl J Med 358 2008 1483 1494
    • (2008) N Engl J Med , vol.358 , pp. 1483-1494
    • Bieber, T.1
  • 3
    • 0346063806 scopus 로고    scopus 로고
    • Atopic dermatitis and the atopic march
    • J.M. Spergel, and A.S. Paller Atopic dermatitis and the atopic march J Allergy Clin Immunol 112 suppl 2003 S118 S127
    • (2003) J Allergy Clin Immunol , vol.112 , Issue.SUPPL.
    • Spergel, J.M.1    Paller, A.S.2
  • 4
    • 79955608104 scopus 로고    scopus 로고
    • Contrasting pathogenesis of atopic dermatitis and psoriasis - Part I: Clinical and pathologic concepts
    • E. Guttman-Yassky, K.E. Nograles, and J.G. Krueger Contrasting pathogenesis of atopic dermatitis and psoriasis - part I: clinical and pathologic concepts J Allergy Clin Immunol 127 2011 1110 1118
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 1110-1118
    • Guttman-Yassky, E.1    Nograles, K.E.2    Krueger, J.G.3
  • 5
    • 33645399288 scopus 로고    scopus 로고
    • Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis
    • C.N. Palmer, A.D. Irvine, and A. Terron-Kwiatkowski Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis Nat Genet 38 2006 441 446
    • (2006) Nat Genet , vol.38 , pp. 441-446
    • Palmer, C.N.1    Irvine, A.D.2    Terron-Kwiatkowski, A.3
  • 7
    • 67649161002 scopus 로고    scopus 로고
    • IL-22-producing "t22" T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17-producing TH17 T cells
    • e2
    • K.E. Nograles, L.C. Zaba, and A. Shemer IL-22-producing "T22" T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17-producing TH17 T cells J Allergy Clin Immunol 123 2009 1244 1252 e2
    • (2009) J Allergy Clin Immunol , vol.123 , pp. 1244-1252
    • Nograles, K.E.1    Zaba, L.C.2    Shemer, A.3
  • 8
    • 14844342604 scopus 로고    scopus 로고
    • IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes
    • K. Boniface, F.X. Bernard, M. Garcia, A.L. Gurney, J.C. Lecron, and F. Morel IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes J Immunol 174 2005 3695 3702
    • (2005) J Immunol , vol.174 , pp. 3695-3702
    • Boniface, K.1    Bernard, F.X.2    Garcia, M.3    Gurney, A.L.4    Lecron, J.C.5    Morel, F.6
  • 9
    • 69249148345 scopus 로고    scopus 로고
    • Cytokine modulation of atopic dermatitis filaggrin skin expression
    • M.D. Howell, B.E. Kim, and P. Gao Cytokine modulation of atopic dermatitis filaggrin skin expression J Allergy Clin Immunol 124 2009 R7 R12
    • (2009) J Allergy Clin Immunol , vol.124
    • Howell, M.D.1    Kim, B.E.2    Gao, P.3
  • 10
    • 54249130813 scopus 로고    scopus 로고
    • Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways
    • K.E. Nograles, L.C. Zaba, and E. Guttman-Yassky Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways Br J Dermatol 159 2008 1092 1102
    • (2008) Br J Dermatol , vol.159 , pp. 1092-1102
    • Nograles, K.E.1    Zaba, L.C.2    Guttman-Yassky, E.3
  • 11
    • 77951890216 scopus 로고    scopus 로고
    • IL-4 regulates skin homeostasis and the predisposition toward allergic skin inflammation
    • S. Sehra, Y. Yao, and M.D. Howell IL-4 regulates skin homeostasis and the predisposition toward allergic skin inflammation J Immunol 184 2010 3186 3190
    • (2010) J Immunol , vol.184 , pp. 3186-3190
    • Sehra, S.1    Yao, Y.2    Howell, M.D.3
  • 12
    • 79955622264 scopus 로고    scopus 로고
    • Contrasting pathogenesis of atopic dermatitis and psoriasis - Part II: Immune cell subsets and therapeutic concepts
    • E. Guttman-Yassky, K.E. Nograles, and J.G. Krueger Contrasting pathogenesis of atopic dermatitis and psoriasis - part II: immune cell subsets and therapeutic concepts J Allergy Clin Immunol 127 2011 1420 1432
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 1420-1432
    • Guttman-Yassky, E.1    Nograles, K.E.2    Krueger, J.G.3
  • 15
    • 42349114941 scopus 로고    scopus 로고
    • Facing psoriasis and atopic dermatitis: Are there more similarities or more differences?
    • D. Wilsmann-Theis, T. Hagemann, J. Jordan, T. Bieber, and N. Novak Facing psoriasis and atopic dermatitis: are there more similarities or more differences? Eur J Dermatol 18 2008 172 180
    • (2008) Eur J Dermatol , vol.18 , pp. 172-180
    • Wilsmann-Theis, D.1    Hagemann, T.2    Jordan, J.3    Bieber, T.4    Novak, N.5
  • 16
    • 0028015581 scopus 로고
    • Differential in situ cytokine gene expression in acute versus chronic atopic dermatitis
    • Q. Hamid, M. Boguniewicz, and D.Y. Leung Differential in situ cytokine gene expression in acute versus chronic atopic dermatitis J Clin Invest 94 1994 870 876
    • (1994) J Clin Invest , vol.94 , pp. 870-876
    • Hamid, Q.1    Boguniewicz, M.2    Leung, D.Y.3
  • 18
    • 0031768650 scopus 로고    scopus 로고
    • Association of increased CD4+ T-cell infiltration with increased IL-16 gene expression in atopic dermatitis
    • S. Laberge, O. Ghaffar, M. Boguniewicz, D.M. Center, D.Y. Leung, and Q. Hamid Association of increased CD4+ T-cell infiltration with increased IL-16 gene expression in atopic dermatitis J Allergy Clin Immunol 102 1998 645 650
    • (1998) J Allergy Clin Immunol , vol.102 , pp. 645-650
    • Laberge, S.1    Ghaffar, O.2    Boguniewicz, M.3    Center, D.M.4    Leung, D.Y.5    Hamid, Q.6
  • 20
    • 0034079576 scopus 로고    scopus 로고
    • Evidence for increased expression of eotaxin and monocyte chemotactic protein-4 in atopic dermatitis
    • R.A. Taha, E.M. Minshall, and D.Y. Leung Evidence for increased expression of eotaxin and monocyte chemotactic protein-4 in atopic dermatitis J Allergy Clin Immunol 105 2000 1002 1007
    • (2000) J Allergy Clin Immunol , vol.105 , pp. 1002-1007
    • Taha, R.A.1    Minshall, E.M.2    Leung, D.Y.3
  • 21
    • 0029098122 scopus 로고
    • Analysis of the cytokine pattern expressed in situ in inhalant allergen patch test reactions of atopic dermatitis patients
    • M. Grewe, S. Walther, K. Gyufko, W. Czech, E. Schopf, and J. Krutmann Analysis of the cytokine pattern expressed in situ in inhalant allergen patch test reactions of atopic dermatitis patients J Invest Dermatol 105 1995 407 410
    • (1995) J Invest Dermatol , vol.105 , pp. 407-410
    • Grewe, M.1    Walther, S.2    Gyufko, K.3    Czech, W.4    Schopf, E.5    Krutmann, J.6
  • 22
    • 0029981818 scopus 로고    scopus 로고
    • Biphasic response against aeroallergen in atopic dermatitis showing a switch from an initial TH2 response to a TH1 response in situ: An immunocytochemical study
    • T. Thepen, E.G. Langeveld-Wildschut, and I.C. Bihari Biphasic response against aeroallergen in atopic dermatitis showing a switch from an initial TH2 response to a TH1 response in situ: an immunocytochemical study J Allergy Clin Immunol 97 1996 828 837
    • (1996) J Allergy Clin Immunol , vol.97 , pp. 828-837
    • Thepen, T.1    Langeveld-Wildschut, E.G.2    Bihari, I.C.3
  • 23
    • 0028176866 scopus 로고
    • Lesional expression of interferon-gamma in atopic eczema
    • M. Grewe, K. Gyufko, E. Schopf, and J. Krutmann Lesional expression of interferon-gamma in atopic eczema Lancet 343 1994 25 26
    • (1994) Lancet , vol.343 , pp. 25-26
    • Grewe, M.1    Gyufko, K.2    Schopf, E.3    Krutmann, J.4
  • 24
    • 0034918980 scopus 로고    scopus 로고
    • Role of aeroallergens in atopic eczema: Proof of concept with the atopy patch test
    • J. Ring, U. Darsow, and H. Behrendt Role of aeroallergens in atopic eczema: proof of concept with the atopy patch test J Am Acad Dermatol 45 suppl 2001 S49 S52
    • (2001) J Am Acad Dermatol , vol.45 , Issue.SUPPL.
    • Ring, J.1    Darsow, U.2    Behrendt, H.3
  • 25
    • 71149092070 scopus 로고    scopus 로고
    • Broad defects in epidermal cornification in atopic dermatitis identified through genomic analysis
    • e58
    • E. Guttman-Yassky, M. Suarez-Farinas, and A. Chiricozzi Broad defects in epidermal cornification in atopic dermatitis identified through genomic analysis J Allergy Clin Immunol 124 2009 1235 1244 e58
    • (2009) J Allergy Clin Immunol , vol.124 , pp. 1235-1244
    • Guttman-Yassky, E.1    Suarez-Farinas, M.2    Chiricozzi, A.3
  • 26
    • 84867887920 scopus 로고    scopus 로고
    • Expanding the psoriasis disease profile: Interrogation of the skin and serum of patients with moderate-to-severe psoriasis
    • [Epub ahed of print]
    • M. Suarez-Farinas, K. Li, and J. Fuentes-Duculan Expanding the psoriasis disease profile: Interrogation of the skin and serum of patients with moderate-to-severe psoriasis J Invest Dermatol 2012 [Epub ahed of print]
    • (2012) J Invest Dermatol
    • Suarez-Farinas, M.1    Li, K.2    Fuentes-Duculan, J.3
  • 27
    • 13844316466 scopus 로고    scopus 로고
    • Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris
    • F. Chamian, M.A. Lowes, and S.L. Lin Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris Proc Natl Acad Sci U S A 102 2005 2075 2080
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 2075-2080
    • Chamian, F.1    Lowes, M.A.2    Lin, S.L.3
  • 30
    • 33845432928 scopus 로고    scopus 로고
    • Adjusting batch effects in microarray expression data using empirical Bayes methods
    • W.E. Johnson, C. Li, and A. Rabinovic Adjusting batch effects in microarray expression data using empirical Bayes methods Biostatistics 8 2007 118 127
    • (2007) Biostatistics , vol.8 , pp. 118-127
    • Johnson, W.E.1    Li, C.2    Rabinovic, A.3
  • 31
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical bayes methods for assessing differential expression in microarray experiments
    • Article3
    • G.K. Smyth Linear models and empirical bayes methods for assessing differential expression in microarray experiments Stat Appl Genet Mol Biol 3 2004 Article3
    • (2004) Stat Appl Genet Mol Biol , vol.3
    • Smyth, G.K.1
  • 32
    • 80052260255 scopus 로고    scopus 로고
    • Interleukin-22 downregulates filaggrin expression and affects expression of profilaggrin processing enzymes
    • D. Gutowska-Owsiak, A.L. Schaupp, M. Salimi, S. Taylor, and G.S. Ogg Interleukin-22 downregulates filaggrin expression and affects expression of profilaggrin processing enzymes Br J Dermatol 165 2011 492 498
    • (2011) Br J Dermatol , vol.165 , pp. 492-498
    • Gutowska-Owsiak, D.1    Schaupp, A.L.2    Salimi, M.3    Taylor, S.4    Ogg, G.S.5
  • 33
    • 33749318470 scopus 로고    scopus 로고
    • Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
    • S.C. Liang, X.Y. Tan, and D.P. Luxenberg Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides J Exp Med 203 2006 2271 2279
    • (2006) J Exp Med , vol.203 , pp. 2271-2279
    • Liang, S.C.1    Tan, X.Y.2    Luxenberg, D.P.3
  • 34
    • 84859759522 scopus 로고    scopus 로고
    • IL-33: A novel danger signal system in atopic dermatitis
    • F. Cevikbas, and M. Steinhoff IL-33: a novel danger signal system in atopic dermatitis J Invest Dermatol 132 2012 1326 1329
    • (2012) J Invest Dermatol , vol.132 , pp. 1326-1329
    • Cevikbas, F.1    Steinhoff, M.2
  • 35
    • 9644302965 scopus 로고    scopus 로고
    • Early up-regulation of Th2 cytokines and late surge of Th1 cytokines in an atopic dermatitis model
    • L. Chen, O. Martinez, L. Overbergh, C. Mathieu, B.S. Prabhakar, and L.S. Chan Early up-regulation of Th2 cytokines and late surge of Th1 cytokines in an atopic dermatitis model Clin Exp Immunol 138 2004 375 387
    • (2004) Clin Exp Immunol , vol.138 , pp. 375-387
    • Chen, L.1    Martinez, O.2    Overbergh, L.3    Mathieu, C.4    Prabhakar, B.S.5    Chan, L.S.6
  • 36
    • 40749156754 scopus 로고    scopus 로고
    • Identification of cellular pathways of "type 1," Th17 T cells, and TNF- and inducible nitric oxide synthase-producing dendritic cells in autoimmune inflammation through pharmacogenomic study of cyclosporine A in psoriasis
    • A.S. Haider, M.A. Lowes, and M. Suarez-Farinas Identification of cellular pathways of "type 1," Th17 T cells, and TNF- and inducible nitric oxide synthase-producing dendritic cells in autoimmune inflammation through pharmacogenomic study of cyclosporine A in psoriasis J Immunol 180 2008 1913 1920
    • (2008) J Immunol , vol.180 , pp. 1913-1920
    • Haider, A.S.1    Lowes, M.A.2    Suarez-Farinas, M.3
  • 38
    • 80052273202 scopus 로고    scopus 로고
    • Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population
    • T. Hirota, A. Takahashi, and M. Kubo Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population Nat Genet 43 2011 893 896
    • (2011) Nat Genet , vol.43 , pp. 893-896
    • Hirota, T.1    Takahashi, A.2    Kubo, M.3
  • 39
    • 33645796414 scopus 로고    scopus 로고
    • Role of CCR5 in the pathogenesis of IL-13-induced inflammation and remodeling
    • B. Ma, W. Liu, and R.J. Homer Role of CCR5 in the pathogenesis of IL-13-induced inflammation and remodeling J Immunol 176 2006 4968 4978
    • (2006) J Immunol , vol.176 , pp. 4968-4978
    • Ma, B.1    Liu, W.2    Homer, R.J.3
  • 40
    • 75949102667 scopus 로고    scopus 로고
    • Interleukin-17 and its target genes: Mechanisms of interleukin-17 function in disease
    • R.M. Onishi, and S.L. Gaffen Interleukin-17 and its target genes: mechanisms of interleukin-17 function in disease Immunology 129 2010 311 321
    • (2010) Immunology , vol.129 , pp. 311-321
    • Onishi, R.M.1    Gaffen, S.L.2
  • 41
    • 79959255489 scopus 로고    scopus 로고
    • Th22 in inflammatory and autoimmune disease: Prospects for therapeutic intervention
    • N. Zhang, H.F. Pan, and D.Q. Ye Th22 in inflammatory and autoimmune disease: prospects for therapeutic intervention Mol Cell Biochem 353 2011 41 46
    • (2011) Mol Cell Biochem , vol.353 , pp. 41-46
    • Zhang, N.1    Pan, H.F.2    Ye, D.Q.3
  • 42
    • 72849131815 scopus 로고    scopus 로고
    • Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling
    • S. Eyerich, K. Eyerich, and D. Pennino Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling J Clin Invest 119 2009 3573 3585
    • (2009) J Clin Invest , vol.119 , pp. 3573-3585
    • Eyerich, S.1    Eyerich, K.2    Pennino, D.3
  • 43
    • 77952746286 scopus 로고    scopus 로고
    • Identification of TNF-related apoptosis-inducing ligand and other molecules that distinguish inflammatory from resident dendritic cells in patients with psoriasis
    • e9
    • L.C. Zaba, J. Fuentes-Duculan, and N.J. Eungdamrong Identification of TNF-related apoptosis-inducing ligand and other molecules that distinguish inflammatory from resident dendritic cells in patients with psoriasis J Allergy Clin Immunol 125 2010 1261 1268 e9
    • (2010) J Allergy Clin Immunol , vol.125 , pp. 1261-1268
    • Zaba, L.C.1    Fuentes-Duculan, J.2    Eungdamrong, N.J.3
  • 44
    • 58149198187 scopus 로고    scopus 로고
    • Low expression of the IL-23/Th17 pathway in atopic dermatitis compared to psoriasis
    • E. Guttman-Yassky, M.A. Lowes, and J. Fuentes-Duculan Low expression of the IL-23/Th17 pathway in atopic dermatitis compared to psoriasis J Immunol 181 2008 7420 7427
    • (2008) J Immunol , vol.181 , pp. 7420-7427
    • Guttman-Yassky, E.1    Lowes, M.A.2    Fuentes-Duculan, J.3
  • 45
    • 79951512605 scopus 로고    scopus 로고
    • Integrative responses to IL-17 and TNF-alpha in human keratinocytes account for key inflammatory pathogenic circuits in psoriasis
    • A. Chiricozzi, E. Guttman-Yassky, and M. Suarez-Farinas Integrative responses to IL-17 and TNF-alpha in human keratinocytes account for key inflammatory pathogenic circuits in psoriasis J Invest Dermatol 131 2011 677 687
    • (2011) J Invest Dermatol , vol.131 , pp. 677-687
    • Chiricozzi, A.1    Guttman-Yassky, E.2    Suarez-Farinas, M.3
  • 46
    • 77956298963 scopus 로고    scopus 로고
    • Evaluation of the psoriasis transcriptome across different studies by gene set enrichment analysis (GSEA)
    • M. Suarez-Farinas, M.A. Lowes, L.C. Zaba, and J.G. Krueger Evaluation of the psoriasis transcriptome across different studies by gene set enrichment analysis (GSEA) PLoS One 5 2010 e10247
    • (2010) PLoS One , vol.5 , pp. 10247
    • Suarez-Farinas, M.1    Lowes, M.A.2    Zaba, L.C.3    Krueger, J.G.4
  • 47
    • 84856458657 scopus 로고    scopus 로고
    • IL-31 regulates differentiation and filaggrin expression in human organotypic skin models
    • e1-8
    • C. Cornelissen, Y. Marquardt, and K. Czaja IL-31 regulates differentiation and filaggrin expression in human organotypic skin models J Allergy Clin Immunol 129 2012 426 433 e1-8
    • (2012) J Allergy Clin Immunol , vol.129 , pp. 426-433
    • Cornelissen, C.1    Marquardt, Y.2    Czaja, K.3
  • 49
    • 77951090253 scopus 로고    scopus 로고
    • Enhanced expression and secretion of antimicrobial peptides in atopic dermatitis and after superficial skin injury
    • J. Harder, S. Dressel, and M. Wittersheim Enhanced expression and secretion of antimicrobial peptides in atopic dermatitis and after superficial skin injury J Invest Dermatol 130 2010 1355 1364
    • (2010) J Invest Dermatol , vol.130 , pp. 1355-1364
    • Harder, J.1    Dressel, S.2    Wittersheim, M.3
  • 50
    • 33745035454 scopus 로고    scopus 로고
    • Elevated serum levels of calcium-binding S100 proteins A8 and A9 reflect disease activity and abnormal differentiation of keratinocytes in psoriasis
    • S. Benoit, A. Toksoy, and M. Ahlmann Elevated serum levels of calcium-binding S100 proteins A8 and A9 reflect disease activity and abnormal differentiation of keratinocytes in psoriasis Br J Dermatol 155 2006 62 66
    • (2006) Br J Dermatol , vol.155 , pp. 62-66
    • Benoit, S.1    Toksoy, A.2    Ahlmann, M.3
  • 51
    • 59949092583 scopus 로고    scopus 로고
    • The antimicrobial protein psoriasin (S100A7) is upregulated in atopic dermatitis and after experimental skin barrier disruption
    • R. Glaser, U. Meyer-Hoffert, and J. Harder The antimicrobial protein psoriasin (S100A7) is upregulated in atopic dermatitis and after experimental skin barrier disruption J Invest Dermatol 129 2009 641 649
    • (2009) J Invest Dermatol , vol.129 , pp. 641-649
    • Glaser, R.1    Meyer-Hoffert, U.2    Harder, J.3
  • 52
    • 15444380167 scopus 로고    scopus 로고
    • Expression patterns of S100A7 (psoriasin) and S100A9 (calgranulin-B) in keratinocyte differentiation
    • H. Martinsson, M. Yhr, and C. Enerback Expression patterns of S100A7 (psoriasin) and S100A9 (calgranulin-B) in keratinocyte differentiation Exp Dermatol 14 2005 161 168
    • (2005) Exp Dermatol , vol.14 , pp. 161-168
    • Martinsson, H.1    Yhr, M.2    Enerback, C.3
  • 53
    • 0037383648 scopus 로고    scopus 로고
    • Phagocyte-specific S100 proteins: A novel group of proinflammatory molecules
    • J. Roth, T. Vogl, C. Sorg, and C. Sunderkotter Phagocyte-specific S100 proteins: a novel group of proinflammatory molecules Trends Immunol 24 2003 155 158
    • (2003) Trends Immunol , vol.24 , pp. 155-158
    • Roth, J.1    Vogl, T.2    Sorg, C.3    Sunderkotter, C.4
  • 54
    • 81555205312 scopus 로고    scopus 로고
    • Inflammation-associated S100 proteins: New mechanisms that regulate function
    • J. Goyette, and C.L. Geczy Inflammation-associated S100 proteins: new mechanisms that regulate function Amino Acids 41 2011 821 842
    • (2011) Amino Acids , vol.41 , pp. 821-842
    • Goyette, J.1    Geczy, C.L.2
  • 56
    • 0037202853 scopus 로고    scopus 로고
    • Hyperzincaemia and hypercalprotectinaemia: A new disorder of zinc metabolism
    • B. Sampson, M.K. Fagerhol, and C. Sunderkotter Hyperzincaemia and hypercalprotectinaemia: a new disorder of zinc metabolism Lancet 360 2002 1742 1745
    • (2002) Lancet , vol.360 , pp. 1742-1745
    • Sampson, B.1    Fagerhol, M.K.2    Sunderkotter, C.3
  • 57
    • 79551643517 scopus 로고    scopus 로고
    • Immunoglobulin e antibody reactivity to bacterial antigens in atopic dermatitis patients
    • K. Reginald, K. Westritschnig, and T. Werfel Immunoglobulin E antibody reactivity to bacterial antigens in atopic dermatitis patients Clin Exp Allergy 41 2011 357 369
    • (2011) Clin Exp Allergy , vol.41 , pp. 357-369
    • Reginald, K.1    Westritschnig, K.2    Werfel, T.3
  • 59
    • 82555169282 scopus 로고    scopus 로고
    • IL-31 serum protein and tissue mRNA levels in patients with atopic dermatitis
    • S. Kim, H.J. Kim, H.S. Yang, E. Kim, I.S. Huh, and J.M. Yang IL-31 serum protein and tissue mRNA levels in patients with atopic dermatitis Ann Dermatol 23 2011 468 473
    • (2011) Ann Dermatol , vol.23 , pp. 468-473
    • Kim, S.1    Kim, H.J.2    Yang, H.S.3    Kim, E.4    Huh, I.S.5    Yang, J.M.6
  • 60
    • 77956881915 scopus 로고    scopus 로고
    • The antimicrobial heterodimer S100A8/S100A9 (calprotectin) is upregulated by bacterial flagellin in human epidermal keratinocytes
    • A. Abtin, L. Eckhart, R. Glaser, R. Gmeiner, M. Mildner, and E. Tschachler The antimicrobial heterodimer S100A8/S100A9 (calprotectin) is upregulated by bacterial flagellin in human epidermal keratinocytes J Invest Dermatol 130 2010 2423 2430
    • (2010) J Invest Dermatol , vol.130 , pp. 2423-2430
    • Abtin, A.1    Eckhart, L.2    Glaser, R.3    Gmeiner, R.4    Mildner, M.5    Tschachler, E.6
  • 61
    • 34447555704 scopus 로고    scopus 로고
    • Complex regulation of S100A8 by IL-17, dexamethasone, IL-4 and IL-13 in HaCat cells (human keratinocyte cell line)
    • B. Bai, K. Yamamoto, H. Sato, H. Sugiura, and T. Tanaka Complex regulation of S100A8 by IL-17, dexamethasone, IL-4 and IL-13 in HaCat cells (human keratinocyte cell line) J Dermatol Sci 47 2007 259 262
    • (2007) J Dermatol Sci , vol.47 , pp. 259-262
    • Bai, B.1    Yamamoto, K.2    Sato, H.3    Sugiura, H.4    Tanaka, T.5
  • 62
    • 77955352799 scopus 로고    scopus 로고
    • Skin inflammation induced by the synergistic action of IL-17A, IL-22, oncostatin M, IL-1α, and TNF-α recapitulates some features of psoriasis
    • [Epub ahead of print]
    • K. Guilloteau, I. Paris, and N. Pedretti Skin inflammation induced by the synergistic action of IL-17A, IL-22, oncostatin M, IL-1α, and TNF-α recapitulates some features of psoriasis J Immunol 2010 [Epub ahead of print]
    • (2010) J Immunol
    • Guilloteau, K.1    Paris, I.2    Pedretti, N.3
  • 63
    • 84859754275 scopus 로고    scopus 로고
    • Vitamin D analog calcipotriol suppresses the Th17 cytokine-induced proinflammatory S100 "alarmins" psoriasin (S100A7) and koebnerisin (S100A15) in psoriasis
    • Z. Hegyi, S. Zwicker, and D. Bureik Vitamin D analog calcipotriol suppresses the Th17 cytokine-induced proinflammatory S100 "alarmins" psoriasin (S100A7) and koebnerisin (S100A15) in psoriasis J Invest Dermatol 132 2012 1416 1424
    • (2012) J Invest Dermatol , vol.132 , pp. 1416-1424
    • Hegyi, Z.1    Zwicker, S.2    Bureik, D.3
  • 64
    • 78651394086 scopus 로고    scopus 로고
    • EGFR and IL-1 signaling synergistically promote keratinocyte antimicrobial defenses in a differentiation-dependent manner
    • A. Johnston, J.E. Gudjonsson, A. Aphale, A.M. Guzman, S.W. Stoll, and J.T. Elder EGFR and IL-1 signaling synergistically promote keratinocyte antimicrobial defenses in a differentiation-dependent manner J Invest Dermatol 131 2011 329 337
    • (2011) J Invest Dermatol , vol.131 , pp. 329-337
    • Johnston, A.1    Gudjonsson, J.E.2    Aphale, A.3    Guzman, A.M.4    Stoll, S.W.5    Elder, J.T.6
  • 65
    • 43449136180 scopus 로고    scopus 로고
    • S100A8/A9, a key mediator for positive feedback growth stimulation of normal human keratinocytes
    • T. Nukui, R. Ehama, and M. Sakaguchi S100A8/A9, a key mediator for positive feedback growth stimulation of normal human keratinocytes J Cell Biochem 104 2008 453 464
    • (2008) J Cell Biochem , vol.104 , pp. 453-464
    • Nukui, T.1    Ehama, R.2    Sakaguchi, M.3
  • 66
    • 58149316658 scopus 로고    scopus 로고
    • Induction of IL-17+ T cell trafficking and development by IFN-gamma: Mechanism and pathological relevance in psoriasis
    • I. Kryczek, A.T. Bruce, and J.E. Gudjonsson Induction of IL-17+ T cell trafficking and development by IFN-gamma: mechanism and pathological relevance in psoriasis J Immunol 181 2008 4733 4741
    • (2008) J Immunol , vol.181 , pp. 4733-4741
    • Kryczek, I.1    Bruce, A.T.2    Gudjonsson, J.E.3
  • 68
    • 84861702522 scopus 로고    scopus 로고
    • Endogenous, or therapeutically induced, type i interferon responses differentially modulate Th1/Th17-mediated autoimmunity in the CNS
    • U. Kalinke, and M. Prinz Endogenous, or therapeutically induced, type I interferon responses differentially modulate Th1/Th17-mediated autoimmunity in the CNS Immunol Cell Biol 90 2012 505 509
    • (2012) Immunol Cell Biol , vol.90 , pp. 505-509
    • Kalinke, U.1    Prinz, M.2


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