Serum cytokine profile in patients with active lupus nephritis

Cytokine

Volumn 60, Issue 2, 2012, Pages 410-416

  Koenig, Katrin Franzika ^a   Groeschl, Isabel ^a   Pesickova, Satu Sinikka ^b   Tesar, Vladimir ^b   Eisenberger, Ute ^c   Trendelenburg, Marten ^a  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b CHARLES UNIVERSITY   (Czech Republic)

^c UNIVERSITY OF BERN   (Switzerland)

Author keywords

Cytokines; Diagnostic marker; Ds DNA; IFN; IL; LN; Lupus nephritis; SLE; TGF 2; TNF ; TNF RII

Indexed keywords

ALPHA2 INTERFERON; BIOLOGICAL MARKER; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR A; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 12P70; INTERLEUKIN 18; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOKINE MULTIPLEX ASSAY; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; DISEASE ACTIVITY; DISEASE DURATION; FEMALE; HUMAN; KIDNEY BIOPSY; LUPUS ERYTHEMATOSUS NEPHRITIS; MALE; MULTICENTER STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; REMISSION; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY;

ADULT; CASE-CONTROL STUDIES; CYTOKINES; FEMALE; FOLLOW-UP STUDIES; HUMANS; KIDNEY; LUPUS NEPHRITIS; MALE; MIDDLE AGED; REPRODUCIBILITY OF RESULTS;

EID: 84866750489     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2012.07.004     Document Type: Article

References (46)

1. Jimenez S., Cervera R., Font J., Ingelmo M. The epidemiology of systemic lupus erythematosus. Clin Rev Allergy Immunol 2003, 25:3-12.
2. Vilar M.J., Sato E.I. Estimating the incidence of systemic lupus erythematosus in a tropical region (Natal, Brazil). Lupus 2002, 11:528-532.
3. Chung E.Y., Kim S.J., Ma X.J. Regulation of cytokine production during phagocytosis of apoptotic cells. Cell Res 2006, 16:154-161.
4. Yap D.Y., Lai K.N. Cytokines and their roles in the pathogenesis of systemic lupus erythematosus: from basics to recent advances. J Biomed Biotechnol 2010, 2010:365083.
5. Adhya Z., Borozdenkova S., Karim M.Y. The role of cytokines as biomarkers in systemic lupus erythematosus and lupus nephritis. Nephrol Dial Transplant 2011, 26:3273-3280.
6. Tan E.M., Cohen A.S., Fries J.F., Masi A.T., McShane D.J., Rothfield N.F., et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982, 25:1271-1277.
7. Weening J.J., D'Agati V.D., Schwartz M.M., Seshan S.V., Alpers C.E., Appel G.B., et al. The classification of glomerulonephritis in systemic lupus erythematosus revisited. J Am Soc Nephrol 2004, 15:241-250.
8. Korbet S.M., Lewis E.J., Schwartz M.M., Reichlin M., Evans J., Rohde R.D. Factors predictive of outcome in severe lupus nephritis. Lupus Nephritis Collaborative Study Group. Am J Kidney Dis 2000, 35:904-914.
9. al-Janadi M., al-Balla S., al-Dalaan A., Raziuddin S. Cytokine profile in systemic lupus erythematosus: rheumatoid arthritis: and other rheumatic diseases. J Clin Immunol 1993, 13:58-67.
10. Atkins R.C. Interleukin-1 in crescentic glomerulonephritis. Kidney Int 1995, 48:576-586.
11. Ballardie F.W., Gordon M.T., Sharpe P.T., Darvill A.M., Cheng H. Intrarenal cytokine mRNA expression and location in normal and IgA nephropathy tissue: TGF alpha, TGF beta, IGF 1, IL-4 and IL-6. Nephrol Dial Transplant 1994, 9:1545-1552.
12. Dohi K., Iwano M., Horii Y. Interleukin 6 (IL-6). Nihon Rinsho 1992, 50:2916-2920.
13. Ishida H., Muchamuel T., Sakaguchi S., Andrade S., Menon S., Howard M. Continuous administration of anti-interleukin 10 antibodies delays onset of autoimmunity in NZB/W F1 mice. J Exp Med 1994, 179:305-310.
14. Tucci M., Lombardi L., Richards H.B., Dammacco F., Silvestris F. Overexpression of interleukin-12 and T helper 1 predominance in lupus nephritis. Clin Exp Immunol 2008, 154:247-254.
15. Tesar V., Jirsa M., Zima T., Kalousova M., Bartunkova J., Stejskalova A., et al. Soluble cytokine receptors in renal vasculitis and lupus nephritis. Med Sci Monit 2002, 8:BR24-BR29.
16. Lit L.C., Wong C.K., Tam L.S., Li E.K., Lam C.W. Raised plasma concentration and ex vivo production of inflammatory chemokines in patients with systemic lupus erythematosus. Ann Rheum Dis 2006, 65:209-215.
17. Tesar V., Masek Z., Rychlik I., Merta M., Bartunkova J., Stejskalova A., et al. Cytokines and adhesion molecules in renal vasculitis and lupus nephritis. Nephrol Dial Transplant 1998, 13:1662-1667.
18. Aderka D., Engelmann H., Maor Y., Brakebusch C., Wallach D. Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors. J Exp Med 1992, 175:323-329.
19. Aderka D., Wysenbeek A., Engelmann H., Cope A.P., Brennan F., Molad Y., et al. Correlation between serum levels of soluble tumor necrosis factor receptor and disease activity in systemic lupus erythematosus. Arthritis Rheum 1993, 36:1111-1120.
20. Studnicka-Benke A., Steiner G., Petera P., Smolen J.S. Tumour necrosis factor alpha and its soluble receptors parallel clinical disease and autoimmune activity in systemic lupus erythematosus. Br J Rheumatol 1996, 35:1067-1074.
21. Roux-Lombard P., Punzi L., Hasler F., Bas S., Todesco S., Gallati H., et al. Soluble tumor necrosis factor receptors in human inflammatory synovial fluids. Arthritis Rheum 1993, 36:485-489.
22. Aringer M., Smolen J.S. Therapeutic blockade of TNF in patients with SLE-Promising or crazy?. Autoimmun Rev 2011.
23. Aringer M., Steiner G., Graninger W.B., Hofler E., Steiner C.W., Smolen J.S. Effects of short-term infliximab therapy on autoantibodies in systemic lupus erythematosus. Arthritis Rheum 2007, 56:274-279.
24. Aringer M., Houssiau F., Gordon C., Graninger W.B., Voll R.E., Rath E., et al. Adverse events and efficacy of TNF-alpha blockade with infliximab in patients with systemic lupus erythematosus: long-term follow-up of 13 patients. Rheumatology (Oxford) 2009, 48:1451-1454.
25. Puertas-Abreu E., Polanco E.R., Azocar M., Mundarain L.A., Nunez-Sotelo C.M., Montano R., et al. Onset of lupus like syndrome in patients with spondyloarthritis treated with anti-TNF-alpha. Int Arch Med 2012, 5:7.
26. Calvani N., Tucci M., Richards H.B., Tartaglia P., Silvestris F. Th1 cytokines in the pathogenesis of lupus nephritis: the role of IL-18. Autoimmun Rev 2005, 4:542-548.
27. Esfandiari E., McInnes I.B., Lindop G., Huang F.P., Field M., Komai-Koma M., et al. A proinflammatory role of IL-18 in the development of spontaneous autoimmune disease. J Immunol 2001, 167:5338-5347.
28. Gigante A., Gasperini M.L., Afeltra A., Barbano B., Margiotta D., Cianci R., et al. Cytokines expression in SLE nephritis. Eur Rev Med Pharmacol Sci 2011, 15:15-24.
29. Lauwerys B.R., Van S.J., Houssiau F.A. Serum IL-12 in systemic lupus erythematosus: absence of p70 heterodimers but presence of p40 monomers correlating with disease activity. Lupus 2002, 11:384-387.
30. Liu X., Bao C., Hu D. Elevated interleukin-18 and skewed Th1:Th2 immune response in lupus nephritis. Rheumatol Int 2010.
31. Llorente L., Zou W., Levy Y., Richaud-Patin Y., Wijdenes J., cocer-Varela J., et al. Role of interleukin 10 in the B lymphocyte hyperactivity and autoantibody production of human systemic lupus erythematosus. J Exp Med 1995, 181:839-844.
32. Lourenco E.V., La C.A. Cytokines in systemic lupus erythematosus. Curr Mol Med 2009, 9:242-254.
33. Uhm W.S., Na K., Song G.W., Jung S.S., Lee T., Park M.H., et al. Cytokine balance in kidney tissue from lupus nephritis patients. Rheumatology (Oxford) 2003, 42:935-938.
34. Wang Y., Ito S., Chino Y., Goto D., Matsumoto I., Murata H., et al. Laser microdissection-based analysis of cytokine balance in the kidneys of patients with lupus nephritis. Clin Exp Immunol 2010, 159:1-10.
35. Amerio P., Frezzolini A., Abeni D., Teofoli P., Girardelli C.R., De P.O., et al. Increased IL-18 in patients with systemic lupus erythematosus: relations with Th-1, Th-2, pro-inflammatory cytokines and disease activity. IL-18 is a marker of disease activity but does not correlate with pro-inflammatory cytokines. Clin Exp Rheumatol 2002, 20:535-538.
36. Park M.C., Park Y.B., Lee S.K. Elevated interleukin-18 levels correlated with disease activity in systemic lupus erythematosus. Clin Rheumatol 2004, 23:225-229.
37. Robak E., Robak T., Wozniacka A., Zak-Prelich M., Sysa-Jedrzejowska A., Stepien H. Proinflammatory interferon-gamma - inducing monokines (interleukin-12, interleukin-18, interleukin-15) - serum profile in patients with systemic lupus erythematosus. Eur Cytokine Netw 2002, 13:364-368.
38. Wong C.K., Ho C.Y., Li E.K., Tam L.S., Lam C.W. Elevated production of interleukin-18 is associated with renal disease in patients with systemic lupus erythematosus. Clin Exp Immunol 2002, 130:345-351.
39. Chang J.T., Segal B.M., Nakanishi K., Okamura H., Shevach E.M. The costimulatory effect of IL-18 on the induction of antigen-specific IFN-gamma production by resting T cells is IL-12 dependent and is mediated by up-regulation of the IL-12 receptor beta2 subunit. Eur J Immunol 2000, 30:1113-1119.
40. Heinzel F.P., Hujer A.M., Ahmed F.N., Rerko R.M. In vivo production and function of IL-12 p40 homodimers. J Immunol 1997, 158:4381-4388.
41. Baechler E.C., Gregersen P.K., Behrens T.W. The emerging role of interferon in human systemic lupus erythematosus. Curr Opin Immunol 2004, 16:801-807.
42. Bengtsson A.A., Sturfelt G., Truedsson L., Blomberg J., Alm G., Vallin H., et al. Activation of type I interferon system in systemic lupus erythematosus correlates with disease activity but not with antiretroviral antibodies. Lupus 2000, 9:664-671.
43. Hooks J.J., Moutsopoulos H.M., Geis S.A., Stahl N.I., Decker J.L., Notkins A.L. Immune interferon in the circulation of patients with autoimmune disease. N Engl J Med 1979, 301:5-8.
44. Preble O.T., Black R.J., Friedman R.M., Klippel J.H., Vilcek J. Systemic lupus erythematosus: presence in human serum of an unusual acid-labile leukocyte interferon. Science 1982, 216:429-431.
45. Ytterberg S.R., Schnitzer T.J. Serum interferon levels in patients with systemic lupus erythematosus. Arthritis Rheum 1982, 25:401-406.
46. Djoba Siawaya J.F., Roberts T., Babb C., Black G., Golakai H.J., Stanley K., et al. An evaluation of commercial fluorescent bead-based luminex cytokine assays. PLoS One 2008, 3:e2535.