-
1
-
-
79953048089
-
Regulation and functions of the IL-10 family of cytokines in inflammation and disease
-
Ouyang, W., Rutz, S., Crellin, N. K., Valdez, P. A., Hymowitz, S. G. Regulation and functions of the IL-10 family of cytokines in inflammation and disease. Annu. Rev. Immunol. 29, 71-109 (2011).
-
(2011)
Annu. Rev. Immunol.
, vol.29
, pp. 71-109
-
-
Ouyang, W.1
Rutz, S.2
Crellin, N.K.3
Valdez, P.A.4
Hymowitz, S.G.5
-
2
-
-
84891702406
-
Therapeutic opportunities of the IL-22-IL-22R1 system
-
Sabat, R., Ouyang, W., Wolk, K. Therapeutic opportunities of the IL-22-IL-22R1 system. Nature Rev. Drug Discov. 13, 21-38 (2014).
-
(2014)
Nature Rev. Drug Discov.
, vol.13
, pp. 21-38
-
-
Sabat, R.1
Ouyang, W.2
Wolk, K.3
-
3
-
-
78651375087
-
IL-19 IL-20 and IL-24: Potential therapeutic targets for autoimmune diseases
-
Leng, R.-X., Pan, H.-F., Tao, J.-H., Ye, D.-Q. IL-19, IL-20 and IL-24: potential therapeutic targets for autoimmune diseases. Expert Opin. Ther. Targets 15, 119-126 (2011).
-
(2011)
Expert Opin. Ther. Targets
, vol.15
, pp. 119-126
-
-
Leng, R.-X.1
Pan, H.-F.2
Tao, J.-H.3
Ye, D.-Q.4
-
4
-
-
0034303102
-
Cloning, expression and initial characterization of interleukin-19 (IL-19), a novel homologue of human interleukin-10 (IL-10)
-
Gallagher, G. et al. Cloning, expression and initial characterization of interleukin-19 (IL-19), a novel homologue of human interleukin-10 (IL-10). Genes Immun. 1, 442-450 (2000).
-
(2000)
Genes Immun
, vol.1
, pp. 442-450
-
-
Gallagher, G.1
-
5
-
-
17744373448
-
Interleukin 20: Discovery, receptor identification, and role in epidermal function
-
Blumberg, H. et al. Interleukin 20: discovery, receptor identification, and role in epidermal function. Cell 104, 9-19 (2001).
-
(2001)
Cell
, vol.104
, pp. 9-19
-
-
Blumberg, H.1
-
6
-
-
0034651583
-
Cloning and characterization of IL-10-related T cell-derived inducible factor (IL-TIF), a novel cytokine structurally related to IL-10 and inducible by IL-9
-
Dumoutier, L., Louahed, J., Renauld, J. C. Cloning and characterization of IL-10-related T cell-derived inducible factor (IL-TIF), a novel cytokine structurally related to IL-10 and inducible by IL-9. J. Immunol. 164, 1814-1819 (2000).
-
(2000)
J. Immunol.
, vol.164
, pp. 1814-1819
-
-
Dumoutier, L.1
Louahed, J.2
Renauld, J.C.3
-
7
-
-
0029558740
-
Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression
-
Jiang, H., Lin, J. J., Su, Z. Z., Goldstein, N. I., Fisher, P. B. Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression. Oncogene 11, 2477-2486 (1995).
-
(1995)
Oncogene
, vol.11
, pp. 2477-2486
-
-
Jiang, H.1
Lin, J.J.2
Su, Z.Z.3
Goldstein, N.I.4
Fisher, P.B.5
-
8
-
-
70450224084
-
Cloning of a novel interleukin (IL)-20-like gene in rainbow trout Oncorhynchus mykiss gives an insight into the evolution of the IL-10 family
-
Wang, T., Diaz-Rosales, P., Martin, S. A., Secombes, C. J. Cloning of a novel interleukin (IL)-20-like gene in rainbow trout Oncorhynchus mykiss gives an insight into the evolution of the IL-10 family. Dev. Comp. Immunol. 34, 158-167 (2010).
-
(2010)
Dev. Comp. Immunol.
, vol.34
, pp. 158-167
-
-
Wang, T.1
Diaz-Rosales, P.2
Martin, S.A.3
Secombes, C.J.4
-
9
-
-
0342803595
-
Induction of a novel cellular homolog of interleukin-10, AK155, by transformation of T lymphocytes with herpesvirus saimiri
-
Knappe, A., Hor, S., Wittmann, S., Fickenscher, H. Induction of a novel cellular homolog of interleukin-10, AK155, by transformation of T lymphocytes with herpesvirus saimiri. J. Virol. 74, 3881-3887 (2000).
-
(2000)
J. Virol.
, vol.74
, pp. 3881-3887
-
-
Knappe, A.1
Hor, S.2
Wittmann, S.3
Fickenscher, H.4
-
10
-
-
28244474539
-
Distal enhancer elements transcribe intergenic RNA in the IL-10 family gene cluster
-
Jones, E. A., Flavell, R. A. Distal enhancer elements transcribe intergenic RNA in the IL-10 family gene cluster. J. Immunol. 175, 7437-7446 (2005).
-
(2005)
J. Immunol.
, vol.175
, pp. 7437-7446
-
-
Jones, E.A.1
Flavell, R.A.2
-
11
-
-
2342659126
-
Interleukin-10 and related cytokines and receptors
-
Pestka, S. et al. Interleukin-10 and related cytokines and receptors. Annu. Rev. Immunol. 22, 929-979 (2004).
-
(2004)
Annu. Rev. Immunol.
, vol.22
, pp. 929-979
-
-
Pestka, S.1
-
12
-
-
0035701768
-
Acinar cells of the pancreas are a target of interleukin-22
-
Aggarwal, S., Xie, M. H., Maruoka, M., Foster, J., Gurney, A. L. Acinar cells of the pancreas are a target of interleukin-22. J. Interferon Cytokine Res. 21, 1047-1053 (2001).
-
(2001)
J. Interferon Cytokine Res.
, vol.21
, pp. 1047-1053
-
-
Aggarwal, S.1
Xie, M.H.2
Maruoka, M.3
Foster, J.4
Gurney, A.L.5
-
13
-
-
0035877120
-
Identification, cloning, and characterization of a novel soluble receptor that binds IL-22 and neutralizes its activity
-
Kotenko, S. V. et al. Identification, cloning, and characterization of a novel soluble receptor that binds IL-22 and neutralizes its activity. J. Immunol. 166, 7096-7103 (2001).
-
(2001)
J. Immunol.
, vol.166
, pp. 7096-7103
-
-
Kotenko, S.V.1
-
14
-
-
0035859898
-
A soluble class II cytokine receptor, IL-22RA2, is a naturally occurring IL-22 antagonist
-
Xu, W. et al. A soluble class II cytokine receptor, IL-22RA2, is a naturally occurring IL-22 antagonist. Proc. Natl Acad. Sci. USA 98, 9511-9516 (2001).
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 9511-9516
-
-
Xu, W.1
-
15
-
-
84890905720
-
Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid
-
Martin, J. C. et al. Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid. Mucosal Immunol. 7, 101-113 (2014).
-
(2014)
Mucosal Immunol
, vol.7
, pp. 101-113
-
-
Martin, J.C.1
-
16
-
-
84868615556
-
IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine
-
Huber, S. et al. IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine. Nature 491, 259-263 (2012).
-
(2012)
Nature
, vol.491
, pp. 259-263
-
-
Huber, S.1
-
17
-
-
84903479494
-
Glycogen synthase kinase-3 Stabilizes the interleukin (IL)-22 receptor from proteasomal degradation in murine lung epithelia
-
Weathington, N. M. et al. Glycogen synthase kinase-3 stabilizes the interleukin (IL)-22 receptor from proteasomal degradation in murine lung epithelia. J. Biol. Chem. 289, 17610-17619 (2014).
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 17610-17619
-
-
Weathington, N.M.1
-
18
-
-
0036604122
-
Cutting edge: Immune cells as sources and targets of the IL-10 family members?
-
Wolk, K., Kunz, S., Asadullah, K., Sabat, R. Cutting edge: immune cells as sources and targets of the IL-10 family members? J. Immunol. 168, 5397-5402 (2002).
-
(2002)
J Immunol
, vol.168
, pp. 5397-5402
-
-
Wolk, K.1
Kunz, S.2
Asadullah, K.3
Sabat, R.4
-
19
-
-
33846906224
-
Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
-
Zheng, Y. et al. Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature 445, 648-651 (2007).
-
(2007)
Nature
, vol.445
, pp. 648-651
-
-
Zheng, Y.1
-
20
-
-
40049083827
-
Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens
-
Zheng, Y. et al. Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens. Nature Med. 14, 282-289 (2008).
-
(2008)
Nature Med
, vol.14
, pp. 282-289
-
-
Zheng, Y.1
-
21
-
-
77953802446
-
IL-22 defines a novel immune pathway of antifungal resistance
-
de Luca, A. et al. IL-22 defines a novel immune pathway of antifungal resistance. Mucosal Immunol. 3, 361-373 (2010).
-
(2010)
Mucosal Immunol
, vol.3
, pp. 361-373
-
-
De Luca, A.1
-
22
-
-
67650474246
-
STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing
-
Pickert, G. et al. STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing. J. Exp. Med. 206, 1465-1472 (2009).
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1465-1472
-
-
Pickert, G.1
-
23
-
-
84881110953
-
IL-22-producing neutrophils contribute to antimicrobial defense and restitution of colonic epithelial integrity during colitis
-
Zindl, C. L. et al. IL-22-producing neutrophils contribute to antimicrobial defense and restitution of colonic epithelial integrity during colitis. Proc. Natl Acad. Sci. USA 110, 12768-12773 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 12768-12773
-
-
Zindl, C.L.1
-
24
-
-
33745209428
-
Prominent production of IL-20 by CD68+/CD11c+ myeloid-derived cells in psoriasis: Gene regulation and cellular effects
-
Wang, F. et al. Prominent production of IL-20 by CD68+/CD11c+ myeloid-derived cells in psoriasis: Gene regulation and cellular effects. J. Investigative Dermatol. 126, 1590-1599 (2006).
-
(2006)
J. Investigative Dermatol.
, vol.126
, pp. 1590-1599
-
-
Wang, F.1
-
25
-
-
46949101054
-
Maturing dendritic cells are an important source of IL-29 and IL-20 that may cooperatively increase the innate immunity of keratinocytes
-
Wolk, K. et al. Maturing dendritic cells are an important source of IL-29 and IL-20 that may cooperatively increase the innate immunity of keratinocytes. J. Leukoc. Biol. 83, 1181-1193 (2008).
-
(2008)
J. Leukoc. Biol.
, vol.83
, pp. 1181-1193
-
-
Wolk, K.1
-
26
-
-
33846940253
-
The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis
-
Sa, S. M. et al. The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis. J. Immunol. 178, 2229-2240 (2007)
-
(2007)
J. Immunol.
, vol.178
, pp. 2229-2240
-
-
Sa, S.M.1
-
27
-
-
36849036400
-
Transcriptional responses of human epidermal keratinocytes to cytokine interleukin-1
-
Yano, S., Banno, T., Walsh, R., Blumenberg, M. Transcriptional responses of human epidermal keratinocytes to cytokine interleukin-1. J. Cell. Physiol. 214, 1-13 (2008).
-
(2008)
J. Cell. Physiol.
, vol.214
, pp. 1-13
-
-
Yano, S.1
Banno, T.2
Walsh, R.3
Blumenberg, M.4
-
28
-
-
33750694954
-
Ultraviolet B light stimulates interleukin-20 expression by human epithelial keratinocytes
-
Hunt, D. W. et al. Ultraviolet B light stimulates interleukin-20 expression by human epithelial keratinocytes. Photochem. Photobiol. 82, 1292-1300 (2006).
-
(2006)
Photochem. Photobiol.
, vol.82
, pp. 1292-1300
-
-
Hunt, D.W.1
-
29
-
-
73249116548
-
The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: A novel immunological cascade with potential relevance in psoriasis
-
Wolk, K. et al. The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis. Eur. J. Immunol. 39, 3570-3581 (2009).
-
(2009)
Eur. J. Immunol.
, vol.39
, pp. 3570-3581
-
-
Wolk, K.1
-
30
-
-
40049098958
-
IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia
-
Aujla, S. J. et al. IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia. Nature Med. 14, 275-281 (2008).
-
(2008)
Nature Med
, vol.14
, pp. 275-281
-
-
Aujla, S.J.1
-
31
-
-
44649131954
-
Potentiation of IL-19 expression in airway epithelia by IL-17A and IL-4/IL-13: Important implications in asthma
-
Huang, F. et al. Potentiation of IL-19 expression in airway epithelia by IL-17A and IL-4/IL-13: important implications in asthma. J. Allergy Clin. Immunol. 121, 1415-1421 (2008).
-
(2008)
J. Allergy Clin. Immunol.
, vol.121
, pp. 1415-1421
-
-
Huang, F.1
-
32
-
-
84873688049
-
IL-22 not simply a Th17 cytokine
-
Rutz, S., Eidenschenk, C., Ouyang, W. IL-22, not simply a Th17 cytokine. Immunol. Rev. 252, 116-132 (2013).
-
(2013)
Immunol. Rev.
, vol.252
, pp. 116-132
-
-
Rutz, S.1
Eidenschenk, C.2
Ouyang, W.3
-
33
-
-
41549135632
-
The biological functions of T helper 17 cell effector cytokines in inflammation
-
Ouyang, W., Kolls, J. K., Zheng, Y. The biological functions of T helper 17 cell effector cytokines in inflammation. Immunity 28, 454-467 (2008).
-
(2008)
Immunity
, vol.28
, pp. 454-467
-
-
Ouyang, W.1
Kolls, J.K.2
Zheng, Y.3
-
34
-
-
68249137286
-
Interleukin-22-producing natural killer cells and lymphoid tissue inducer-like cells in mucosal immunity
-
Colonna, M. Interleukin-22-producing natural killer cells and lymphoid tissue inducer-like cells in mucosal immunity. Immunity 31, 15-23 (2009).
-
(2009)
Immunity
, vol.31
, pp. 15-23
-
-
Colonna, M.1
-
35
-
-
57849131584
-
Human fetal lymphoid tissue-inducer cells are interleukin 17-producing precursors to RORC+ CD127+ natural killer-like cells
-
Cupedo, T. et al. Human fetal lymphoid tissue-inducer cells are interleukin 17-producing precursors to RORC+ CD127+ natural killer-like cells. Nature Immunol. 10, 66-74 (2009).
-
(2009)
Nature Immunol
, vol.10
, pp. 66-74
-
-
Cupedo, T.1
-
36
-
-
68649126866
-
Interleukin-17-producing T cells selectively expand in response to pathogen products and environmental signals
-
Martin, B., Hirota, K., Cua, D. J., Stockinger, B., Veldhoen, M. Interleukin-17-producing T cells selectively expand in response to pathogen products and environmental signals. Immunity 31, 321-330 (2009).
-
(2009)
Immunity
, vol.31
, pp. 321-330
-
-
Martin, B.1
Hirota, K.2
Cua, D.J.3
Stockinger, B.4
Veldhoen, M.5
-
37
-
-
68649088121
-
Interleukin-1 and IL-23 induce innate IL-17 production from T cells, amplifying Th17 responses and autoimmunity
-
Sutton, C. E. et al. Interleukin-1 and IL-23 induce innate IL-17 production from T cells, amplifying Th17 responses and autoimmunity. Immunity 31, 331-341 (2009).
-
(2009)
Immunity
, vol.31
, pp. 331-341
-
-
Sutton, C.E.1
-
38
-
-
60549102720
-
Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22
-
Takatori, H. et al. Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22. J. Exp. Med. 206, 35-41 (2009).
-
(2009)
J. Exp. Med.
, vol.206
, pp. 35-41
-
-
Takatori, H.1
-
39
-
-
84872977452
-
Innate lymphoid cells-a proposal for uniform nomenclature
-
Spits, H. et al. Innate lymphoid cells-a proposal for uniform nomenclature. Nature Rev. Immunology 13, 145-149 (2013).
-
(2013)
Nature Rev. Immunology
, vol.13
, pp. 145-149
-
-
Spits, H.1
-
40
-
-
57449118239
-
Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense
-
Satoh-Takayama, N. et al. Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense. Immunity 29, 958-970 (2008).
-
(2008)
Immunity
, vol.29
, pp. 958-970
-
-
Satoh-Takayama, N.1
-
41
-
-
57849145994
-
Influence of the transcription factor ROR?t on the development of NKp46+ cell populations in gut and skin
-
Luci, C. et al. Influence of the transcription factor ROR?t on the development of NKp46+ cell populations in gut and skin. Nature Immunol. 10, 75-82 (2009).
-
(2009)
Nature Immunol
, vol.10
, pp. 75-82
-
-
Luci, C.1
-
42
-
-
57849117363
-
RORt and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells
-
Sanos, S. L. et al. ROR?t and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells. Nature Immunol. 10, 83-91 (2009).
-
(2009)
Nature Immunol
, vol.10
, pp. 83-91
-
-
Sanos, S.L.1
-
43
-
-
59649099774
-
A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity
-
Cella, M. et al. A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity. Nature 457, 722-725 (2009).
-
(2009)
Nature
, vol.457
, pp. 722-725
-
-
Cella, M.1
-
44
-
-
77149135298
-
Human NKp44+IL-22+ cells and LTi-like cells constitute a stable RORC+ lineage distinct from conventional natural killer cells
-
Crellin, N. K., Trifari, S., Kaplan, C. D., Cupedo, T., Spits, H. Human NKp44+IL-22+ cells and LTi-like cells constitute a stable RORC+ lineage distinct from conventional natural killer cells. J. Exp. Med. 207, 281-290 (2010).
-
(2010)
J. Exp. Med.
, vol.207
, pp. 281-290
-
-
Crellin, N.K.1
Trifari, S.2
Kaplan, C.D.3
Cupedo, T.4
Spits, H.5
-
45
-
-
33749318470
-
Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
-
Liang, S. C. et al. Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J. Exp. Med. 203, 2271-2279 (2006)
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2271-2279
-
-
Liang, S.C.1
-
46
-
-
33751120140
-
Expression and regulation of IL-22 in the IL-17-producing CD4+ T lymphocytes
-
Chung, Y. et al. Expression and regulation of IL-22 in the IL-17-producing CD4+ T lymphocytes. Cell Res. 16, 902-907 (2006).
-
(2006)
Cell Res
, vol.16
, pp. 902-907
-
-
Chung, Y.1
-
47
-
-
2142659288
-
IL-22 a Th1 cytokine that targets the pancreas and select other peripheral tissues
-
Gurney, A. L. IL-22, a Th1 cytokine that targets the pancreas and select other peripheral tissues. Int. Immunopharmacol. 4, 669-677 (2004).
-
(2004)
Int. Immunopharmacol.
, vol.4
, pp. 669-677
-
-
Gurney, A.L.1
-
48
-
-
67651154105
-
Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells
-
Duhen, T., Geiger, R., Jarrossay, D., Lanzavecchia, A., Sallusto, F. Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. Nature Immunol. 10, 857-863 (2009).
-
(2009)
Nature Immunol
, vol.10
, pp. 857-863
-
-
Duhen, T.1
Geiger, R.2
Jarrossay, D.3
Lanzavecchia, A.4
Sallusto, F.5
-
49
-
-
72849131815
-
Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling
-
Eyerich, S. et al. Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling. J. Clin. Invest. 119, 3573-3585 (2009).
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 3573-3585
-
-
Eyerich, S.1
-
50
-
-
67651171182
-
Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17 TH1 and TH2 cells
-
Trifari, S., Kaplan, C. D., Tran, E. H., Crellin, N. K., Spits, H. Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells. Nature Immunol. 10, 864-871 (2009).
-
(2009)
Nature Immunol
, vol.10
, pp. 864-871
-
-
Trifari, S.1
Kaplan, C.D.2
Tran, E.H.3
Crellin, N.K.4
Spits, H.5
-
51
-
-
84870876967
-
Th22 cells are an important source of IL-22 for host protection against enteropathogenic bacteria
-
Basu, R. et al. Th22 cells are an important source of IL-22 for host protection against enteropathogenic bacteria. Immunity 37, 1061-1075 (2012).
-
(2012)
Immunity
, vol.37
, pp. 1061-1075
-
-
Basu, R.1
-
52
-
-
36248965294
-
TGF-and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell-mediated pathology
-
McGeachy, M. J. et al. TGF-? and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell-mediated pathology. Nature Immunol. 8, 1390-1397 (2007).
-
(2007)
Nature Immunol
, vol.8
, pp. 1390-1397
-
-
McGeachy, M.J.1
-
53
-
-
34547204946
-
Essential autocrine regulation by IL-21 in the generation of inflammatory T cells
-
Nurieva, R. et al. Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. Nature 448, 480-483 (2007).
-
(2007)
Nature
, vol.448
, pp. 480-483
-
-
Nurieva, R.1
-
54
-
-
40049103352
-
IL-22 is expressed by Th17 cells in an IL-23-dependent fashion, but not required for the development of autoimmune encephalomyelitis
-
Kreymborg, K. et al. IL-22 is expressed by Th17 cells in an IL-23-dependent fashion, but not required for the development of autoimmune encephalomyelitis. J. Immunol. 179, 8098-8104 (2007).
-
(2007)
J. Immunol.
, vol.179
, pp. 8098-8104
-
-
Kreymborg, K.1
-
55
-
-
65549142116
-
Differential IL-23 requirement for IL-22 and IL-17A production during innate immunity against Salmonella enterica serovar Enteritidis
-
Siegemund, S. et al. Differential IL-23 requirement for IL-22 and IL-17A production during innate immunity against Salmonella enterica serovar Enteritidis. Int. Immunol. 21, 555-565 (2009).
-
(2009)
Int. Immunol.
, vol.21
, pp. 555-565
-
-
Siegemund, S.1
-
56
-
-
77950548359
-
Interleukin-23 promotes Th17 differentiation by inhibiting T-bet and FoxP3 and is required for elevation of interleukin-22, but not interleukin-21, in autoimmune experimental arthritis
-
Mus, A. M. C. et al. Interleukin-23 promotes Th17 differentiation by inhibiting T-bet and FoxP3 and is required for elevation of interleukin-22, but not interleukin-21, in autoimmune experimental arthritis. Arthritis Rheum. 62, 1043-1050 (2010).
-
(2010)
Arthritis Rheum
, vol.62
, pp. 1043-1050
-
-
Mus, A.M.C.1
-
57
-
-
67649216137
-
Regulation of T cell activation by Notch ligand, DLL4, promotes IL-17 production and Rorc activation
-
Mukherjee, S., Schaller, M. A., Neupane, R., Kunkel, S. L., Lukacs, N. W. Regulation of T cell activation by Notch ligand, DLL4, promotes IL-17 production and Rorc activation. J. Immunol. 182, 7381-7388 (2009).
-
(2009)
J. Immunol.
, vol.182
, pp. 7381-7388
-
-
Mukherjee, S.1
Schaller, M.A.2
Neupane, R.3
Kunkel, S.L.4
Lukacs, N.W.5
-
58
-
-
77950534839
-
Notch signaling drives IL-22 secretion in CD4+ T cells by stimulating the aryl hydrocarbon receptor
-
Alam, M. S. et al. Notch signaling drives IL-22 secretion in CD4+ T cells by stimulating the aryl hydrocarbon receptor. Proc. Natl Acad. Sci. USA 107, 5943-5948 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 5943-5948
-
-
Alam, M.S.1
-
59
-
-
60549095448
-
Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells
-
Veldhoen, M., Hirota, K., Christensen, J., O.&apos, Garra, A., Stockinger, B. Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells. J. Exp. Med. 206, 43-49 (2009).
-
(2009)
J. Exp. Med.
, vol.206
, pp. 43-49
-
-
Veldhoen, M.1
Hirota, K.2
Christensen, J.O.3
Apos4
Garra, A.5
Stockinger, B.6
-
60
-
-
42649106556
-
The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins
-
Veldhoen, M. et al. The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins. Nature 453, 106-109 (2008).
-
(2008)
Nature
, vol.453
, pp. 106-109
-
-
Veldhoen, M.1
-
61
-
-
0035873471
-
Cutting edge: FISP (IL-4-induced secreted protein), a novel cytokine-like molecule secreted by Th2 cells
-
Schaefer, G., Venkataraman, C., Schindler, U. Cutting edge: FISP (IL-4-induced secreted protein), a novel cytokine-like molecule secreted by Th2 cells. J. Immunol. 166, 5859-5863 (2001).
-
(2001)
J. Immunol.
, vol.166
, pp. 5859-5863
-
-
Schaefer, G.1
Venkataraman, C.2
Schindler, U.3
-
62
-
-
33845589222
-
Involvement of GATA3 in protein kinase C ?-induced Th2 cytokine expression
-
Stevens, L. et al. Involvement of GATA3 in protein kinase C ?-induced Th2 cytokine expression. Eur. J. Immunol. 36, 3305-3314 (2006).
-
(2006)
Eur. J. Immunol.
, vol.36
, pp. 3305-3314
-
-
Stevens, L.1
-
63
-
-
79955043870
-
Stat6 and c-Jun mediate Th2 cell-specific IL-24 gene expression
-
Sahoo, A. et al. Stat6 and c-Jun mediate Th2 cell-specific IL-24 gene expression. J. Immunol. 186, 4098-4109 (2011).
-
(2011)
J. Immunol.
, vol.186
, pp. 4098-4109
-
-
Sahoo, A.1
-
64
-
-
34548133583
-
Development, cytokine profile and function of human interleukin 17-producing helper T cells
-
Wilson, N. J. et al. Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nature Immunol. 8, 950-957 (2007).
-
(2007)
Nature Immunol
, vol.8
, pp. 950-957
-
-
Wilson, N.J.1
-
65
-
-
44049104564
-
The differentiation of human TH-17 cells requires transforming growth factor-and induction of the nuclear receptor RORt
-
Manel, N., Unutmaz, D., Littman, D. R. The differentiation of human TH-17 cells requires transforming growth factor-? and induction of the nuclear receptor ROR?t. Nature Immunol. 9, 641-649 (2008).
-
(2008)
Nature Immunol
, vol.9
, pp. 641-649
-
-
Manel, N.1
Unutmaz, D.2
Littman, D.R.3
-
66
-
-
78650183459
-
Regulation of cytokine secretion in human CD127+ LTi-like innate lymphoid cells by Toll-like receptor 2
-
Crellin, N. K. et al. Regulation of cytokine secretion in human CD127+ LTi-like innate lymphoid cells by Toll-like receptor 2. Immunity 33, 752-764 (2010).
-
(2010)
Immunity
, vol.33
, pp. 752-764
-
-
Crellin, N.K.1
-
67
-
-
84883172356
-
Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens
-
Satpathy, A. T. et al. Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens. Nature Immunol. 14, 937-948 (2013).
-
(2013)
Nature Immunol
, vol.14
, pp. 937-948
-
-
Satpathy, A.T.1
-
68
-
-
77955499820
-
TLR5 signaling stimulates the innate production of IL-17 and IL-22 by CD3negCD127+ immune cells in spleen and mucosa
-
Van Maele, L. et al. TLR5 signaling stimulates the innate production of IL-17 and IL-22 by CD3negCD127+ immune cells in spleen and mucosa. J. Immunol. 185, 1177-1185 (2010).
-
(2010)
J. Immunol.
, vol.185
, pp. 1177-1185
-
-
Van Maele, L.1
-
69
-
-
70049098070
-
Origin of the lamina propria dendritic cell network
-
Bogunovic, M. et al. Origin of the lamina propria dendritic cell network. Immunity 31, 513-525 (2009).
-
(2009)
Immunity
, vol.31
, pp. 513-525
-
-
Bogunovic, M.1
-
70
-
-
70049099836
-
Intestinal lamina propria dendritic cell subsets have different origin and functions
-
Varol, C. et al. Intestinal lamina propria dendritic cell subsets have different origin and functions. Immunity 31, 502-512 (2009).
-
(2009)
Immunity
, vol.31
, pp. 502-512
-
-
Varol, C.1
-
71
-
-
34249298734
-
Control of intestinal homeostasis by regulatory T cells and dendritic cells
-
Coombes, J. L., Maloy, K. J. Control of intestinal homeostasis by regulatory T cells and dendritic cells. Semin. Immunol. 19, 116-126 (2007).
-
(2007)
Semin. Immunol.
, vol.19
, pp. 116-126
-
-
Coombes, J.L.1
Maloy, K.J.2
-
72
-
-
84857444876
-
Interleukin 23 production by intestinal CD103+CD11b+ dendritic cells in response to bacterial flagellin enhances mucosal innate immune defense
-
Kinnebrew, M. A. et al. Interleukin 23 production by intestinal CD103+CD11b+ dendritic cells in response to bacterial flagellin enhances mucosal innate immune defense. Immunity 36, 276-287 (2012).
-
(2012)
Immunity
, vol.36
, pp. 276-287
-
-
Kinnebrew, M.A.1
-
73
-
-
75749133608
-
Bacterial flagellin stimulates Toll-like receptor 5-dependent defense against vancomycin-resistant Enterococcus infection
-
Kinnebrew, M. A. et al. Bacterial flagellin stimulates Toll-like receptor 5-dependent defense against vancomycin-resistant Enterococcus infection. J. Infect. Dis. 201, 534-543 (2010).
-
(2010)
J. Infect. Dis.
, vol.201
, pp. 534-543
-
-
Kinnebrew, M.A.1
-
74
-
-
80052966918
-
IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentium
-
Ota, N. et al. IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentium. Nature Immunol. 12, 941-948 (2011).
-
(2011)
Nature Immunol
, vol.12
, pp. 941-948
-
-
Ota, N.1
-
75
-
-
79960500206
-
Lymphotoxin controls the IL-22 protection pathway in gut innate lymphoid cells during mucosal pathogen challenge
-
Tumanov, A. V. et al. Lymphotoxin controls the IL-22 protection pathway in gut innate lymphoid cells during mucosal pathogen challenge. Cell Host Microbe 10, 44-53 (2011).
-
(2011)
Cell Host Microbe
, vol.10
, pp. 44-53
-
-
Tumanov, A.V.1
-
76
-
-
7644235586
-
The lymphotoxin-receptor is critical for control of murine Citrobacter rodentium-induced colitis
-
Spahn, T. W. et al. The lymphotoxin-receptor is critical for control of murine Citrobacter rodentium-induced colitis. Gastroenterology 127, 1463-1473 (2004).
-
(2004)
Gastroenterology
, vol.127
, pp. 1463-1473
-
-
Spahn, T.W.1
-
77
-
-
77950022870
-
Lymphotoxin receptor signaling in intestinal epithelial cells orchestrates innate immune responses against mucosal bacterial infection
-
Wang, Y. et al. Lymphotoxin ? receptor signaling in intestinal epithelial cells orchestrates innate immune responses against mucosal bacterial infection. Immunity 32, 403-413 (2010).
-
(2010)
Immunity
, vol.32
, pp. 403-413
-
-
Wang, Y.1
-
78
-
-
84874082076
-
CX3CR1+ macrophages support IL-22 production by innate lymphoid cells during infection with Citrobacter rodentium
-
Manta, C. et al. CX3CR1+ macrophages support IL-22 production by innate lymphoid cells during infection with Citrobacter rodentium. Mucosal Immunol. 6, 177-188 (2013)
-
(2013)
Mucosal Immunol
, vol.6
, pp. 177-188
-
-
Manta, C.1
-
79
-
-
78751706261
-
CD4+ lymphoid tissue-inducer cells promote innate immunity in the gut
-
Sonnenberg, G. F., Monticelli, L. A., Elloso, M. M., Fouser, L. A., Artis, D. CD4+ lymphoid tissue-inducer cells promote innate immunity in the gut. Immunity 34, 122-134 (2011).
-
(2011)
Immunity
, vol.34
, pp. 122-134
-
-
Sonnenberg, G.F.1
Monticelli, L.A.2
Elloso, M.M.3
Fouser, L.A.4
Artis, D.5
-
80
-
-
84870900504
-
Ly6Chi monocytes in the inflamed colon give rise to proinflammatory effector cells and migratory antigen-presenting cells
-
Zigmond, E. et al. Ly6Chi monocytes in the inflamed colon give rise to proinflammatory effector cells and migratory antigen-presenting cells. Immunity 37, 1076-1090 (2012).
-
(2012)
Immunity
, vol.37
, pp. 1076-1090
-
-
Zigmond, E.1
-
81
-
-
79956319462
-
The Nod2 sensor promotes intestinal pathogen eradication via the chemokine CCL2-dependent recruitment of inflammatory monocytes
-
Kim, Y.-G. et al. The Nod2 sensor promotes intestinal pathogen eradication via the chemokine CCL2-dependent recruitment of inflammatory monocytes. Immunity 34, 769-780 (2011).
-
(2011)
Immunity
, vol.34
, pp. 769-780
-
-
Kim, Y.-G.1
-
82
-
-
78449291921
-
Skin function for human CD1a-reactive T cells
-
Colonna, M. Skin function for human CD1a-reactive T cells. Nature Immunol. 11, 1079-1080 (2010).
-
(2010)
Nature Immunol
, vol.11
, pp. 1079-1080
-
-
Colonna, M.1
-
83
-
-
78449298644
-
CD1a-autoreactive T cells are a normal component of the human T cell repertoire
-
de Jong, A. et al. CD1a-autoreactive T cells are a normal component of the human T cell repertoire. Nature Immunol. 11, 1102-1109 (2010).
-
(2010)
Nature Immunol
, vol.11
, pp. 1102-1109
-
-
De Jong, A.1
-
84
-
-
79955030498
-
Border patrol: Regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22
-
Sonnenberg, G. F., Fouser, L. A., Artis, D. Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22. Nature Immunol. 12, 383-390 (2011).
-
(2011)
Nature Immunol
, vol.12
, pp. 383-390
-
-
Sonnenberg, G.F.1
Fouser, L.A.2
Artis, D.3
-
85
-
-
84883883299
-
Modulation of respiratory dendritic cells during Klebsiella pneumonia infection
-
Hackstein, H. et al. Modulation of respiratory dendritic cells during Klebsiella pneumonia infection. Respir. Res. 14, 91 (2013).
-
(2013)
Respir. Res.
, vol.14
, pp. 91
-
-
Hackstein, H.1
-
86
-
-
80053898773
-
IL10 family member genes IL19 and IL20 are associated with recurrent wheeze after respiratory syncytial virus bronchiolitis
-
Ermers, M. J. et al. IL10 family member genes IL19 and IL20 are associated with recurrent wheeze after respiratory syncytial virus bronchiolitis. Pediatr. Res. 70, 518-523 (2011).
-
(2011)
Pediatr. Res.
, vol.70
, pp. 518-523
-
-
Ermers, M.J.1
-
87
-
-
84861989207
-
Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria
-
Sonnenberg, G. F. et al. Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria. Science 336, 1321-1325 (2012).
-
(2012)
Science
, vol.336
, pp. 1321-1325
-
-
Sonnenberg, G.F.1
-
88
-
-
84958544987
-
Role of IL-22 in microbial host defense
-
Eidenschenk, C., Rutz, S., Liesenfeld, O., Ouyang, W. Role of IL-22 in microbial host defense. Curr. Top. Microbiol. Immunol. 380, 213-236 (2014).
-
(2014)
Curr. Top. Microbiol. Immunol.
, vol.380
, pp. 213-236
-
-
Eidenschenk, C.1
Rutz, S.2
Liesenfeld, O.3
Ouyang, W.4
-
89
-
-
84858587977
-
Interleukin-22 is produced by invariant natural killer T lymphocytes during influenza A virus infection: Potential role in protection against lung epithelial damages
-
Paget, C. et al. Interleukin-22 is produced by invariant natural killer T lymphocytes during influenza A virus infection: potential role in protection against lung epithelial damages. J. Biol. Chem. 287, 8816-8829 (2012).
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 8816-8829
-
-
Paget, C.1
-
90
-
-
33646552450
-
IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: A potential role in psoriasis
-
Wolk, K. et al. IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis. Eur. J. Immunol. 36, 1309-1323 (2006).
-
(2006)
Eur. J. Immunol.
, vol.36
, pp. 1309-1323
-
-
Wolk, K.1
-
91
-
-
14844342604
-
IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes
-
Boniface, K. et al. IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes. J. Immunol. 174, 3695-3702 (2005).
-
(2005)
J. Immunol.
, vol.174
, pp. 3695-3702
-
-
Boniface, K.1
-
92
-
-
68849124464
-
The role of the novel Th17 cytokine IL-26 in intestinal inflammation
-
Dambacher, J. et al. The role of the novel Th17 cytokine IL-26 in intestinal inflammation. Gut 58, 1207-1217 (2009).
-
(2009)
Gut
, vol.58
, pp. 1207-1217
-
-
Dambacher, J.1
-
93
-
-
84894055913
-
The cytokine IL-22 promotes pathogen colonization by suppressing related commensal bacteria
-
Behnsen, J. et al. The cytokine IL-22 promotes pathogen colonization by suppressing related commensal bacteria. Immunity 40, 262-273 (2014).
-
(2014)
Immunity
, vol.40
, pp. 262-273
-
-
Behnsen, J.1
-
94
-
-
84863338466
-
Zinc sequestration by the neutrophil protein calprotectin enhances Salmonella growth in the inflamed gut
-
Liu, J. Z. et al. Zinc sequestration by the neutrophil protein calprotectin enhances Salmonella growth in the inflamed gut. Cell Host Microbe 11, 227-239 (2012).
-
(2012)
Cell Host Microbe
, vol.11
, pp. 227-239
-
-
Liu, J.Z.1
-
95
-
-
65549099573
-
Lipocalin-2 resistance confers an advantage to Salmonella enterica serotype Typhimurium for growth and survival in the inflamed intestine
-
Raffatellu, M. et al. Lipocalin-2 resistance confers an advantage to Salmonella enterica serotype Typhimurium for growth and survival in the inflamed intestine. Cell Host Microbe 5, 476-486 (2009).
-
(2009)
Cell Host Microbe
, vol.5
, pp. 476-486
-
-
Raffatellu, M.1
-
96
-
-
79958246450
-
Salmonella-induced mucosal lectin RegIII kills competing gut microbiota
-
Stelter, C. et al. Salmonella-induced mucosal lectin RegIII kills competing gut microbiota. PLoS ONE 6, e20749 (2011).
-
(2011)
PLoS ONE
, vol.6
, pp. e20749
-
-
Stelter, C.1
-
97
-
-
84876501381
-
The dynamics of gut-associated microbial communities during inflammation
-
Winter, S. E., Lopez, C. A., Baumler, A. J. The dynamics of gut-associated microbial communities during inflammation. EMBO Rep. 14, 319-327 (2013).
-
(2013)
EMBO Rep
, vol.14
, pp. 319-327
-
-
Winter, S.E.1
Lopez, C.A.2
Baumler, A.J.3
-
98
-
-
84880821538
-
Signaling via the IL-20 receptor inhibits cutaneous production of IL-1? and IL-17A to promote infection with methicillin-resistant Staphylococcus aureus
-
Myles, I. A. et al. Signaling via the IL-20 receptor inhibits cutaneous production of IL-1? and IL-17A to promote infection with methicillin-resistant Staphylococcus aureus. Nature Immunol. 14, 804-811 (2013).
-
(2013)
Nature Immunol
, vol.14
, pp. 804-811
-
-
Myles, I.A.1
-
99
-
-
30444459066
-
MyD88 mediates neutrophil recruitment initiated by IL-1R but not TLR2 activation in immunity against Staphylococcus aureus
-
Miller, L. S. et al. MyD88 mediates neutrophil recruitment initiated by IL-1R but not TLR2 activation in immunity against Staphylococcus aureus. Immunity 24, 79-91 (2006).
-
(2006)
Immunity
, vol.24
, pp. 79-91
-
-
Miller, L.S.1
-
100
-
-
77951861324
-
IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice
-
Cho, J. S. et al. IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice. J. Clin. Invest. 120, 1762-1773 (2010).
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 1762-1773
-
-
Cho, J.S.1
-
101
-
-
33847279025
-
Pathogenesis and therapy of psoriasis
-
Lowes, M. A., Bowcock, A. M., Krueger, J. G. Pathogenesis and therapy of psoriasis. Nature 445, 866-873 (2007).
-
(2007)
Nature
, vol.445
, pp. 866-873
-
-
Lowes, M.A.1
Bowcock, A.M.2
Krueger, J.G.3
-
102
-
-
77949889459
-
IL-24 transgenic mice: In vivo evidence of overlapping functions for IL-20 IL-22 and IL-24 in the epidermis
-
He, M., Liang, P. IL-24 transgenic mice: in vivo evidence of overlapping functions for IL-20, IL-22, and IL-24 in the epidermis. J. Immunol. 184, 1793-1798 (2010).
-
(2010)
J. Immunol.
, vol.184
, pp. 1793-1798
-
-
He, M.1
Liang, P.2
-
103
-
-
67349195975
-
IL-22 and IL-20 are key mediators of the epidermal alterations in psoriasis while IL-17 and IFN- are not
-
Wolk, K. et al. IL-22 and IL-20 are key mediators of the epidermal alterations in psoriasis while IL-17 and IFN- are not. J. Mol. Med. 87, 523-536 (2009).
-
(2009)
J. Mol. Med.
, vol.87
, pp. 523-536
-
-
Wolk, K.1
-
104
-
-
4143095716
-
IL-22 increases the innate immunity of tissues
-
Wolk, K. et al. IL-22 increases the innate immunity of tissues. Immunity 21, 241-254 (2004)
-
(2004)
Immunity
, vol.21
, pp. 241-254
-
-
Wolk, K.1
-
105
-
-
0346364791
-
Epidermal overexpression of interleukin-19 and-20 mRNA in psoriatic skin disappears after short-term treatment with cyclosporine a or calcipotriol
-
Romer, J. et al. Epidermal overexpression of interleukin-19 and-20 mRNA in psoriatic skin disappears after short-term treatment with cyclosporine a or calcipotriol. J. Invest. Dermatol. 121, 1306-1311 (2003).
-
(2003)
J. Invest. Dermatol.
, vol.121
, pp. 1306-1311
-
-
Romer, J.1
-
106
-
-
27544481752
-
The dynamics of gene expression of interleukin-19 and interleukin-20 and their receptors in psoriasis
-
Otkjaer, K. et al. The dynamics of gene expression of interleukin-19 and interleukin-20 and their receptors in psoriasis. Br. J. Dermatol. 153, 911-918 (2005).
-
(2005)
Br. J. Dermatol.
, vol.153
, pp. 911-918
-
-
Otkjaer, K.1
-
107
-
-
78649690842
-
Distinct roles of IL-22 in human psoriasis and inflammatory bowel disease
-
Ouyang, W. Distinct roles of IL-22 in human psoriasis and inflammatory bowel disease. Cytokine Growth Factor Rev. 21, 435-441 (2010).
-
(2010)
Cytokine Growth Factor Rev
, vol.21
, pp. 435-441
-
-
Ouyang, W.1
-
108
-
-
33645829078
-
IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration
-
Brand, S. et al. IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration. Am. J. Physiol. Gastrointest. Liver Physiol. 290, G827-G838 (2006).
-
(2006)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.290
, pp. G827-G838
-
-
Brand, S.1
-
109
-
-
24144477540
-
Interleukin-22, a member of the IL-10 subfamily, induces inflammatory responses in colonic subepithelial myofibroblasts
-
Andoh, A. et al. Interleukin-22, a member of the IL-10 subfamily, induces inflammatory responses in colonic subepithelial myofibroblasts. Gastroenterology 129, 969-984 (2005).
-
(2005)
Gastroenterology
, vol.129
, pp. 969-984
-
-
Andoh, A.1
-
110
-
-
38849141814
-
IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis
-
Sugimoto, K. et al. IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis. J. Clin. Invest. 118, 534-544 (2008).
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 534-544
-
-
Sugimoto, K.1
-
111
-
-
57449090428
-
Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease
-
Zenewicz, L. A. et al. Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease. Immunity 29, 947-957 (2008).
-
(2008)
Immunity
, vol.29
, pp. 947-957
-
-
Zenewicz, L.A.1
-
112
-
-
77953143699
-
Activation of epithelial STAT3 regulates intestinal homeostasis
-
Neufert, C. et al. Activation of epithelial STAT3 regulates intestinal homeostasis. Cell Cycle 9, 652-655 (2010).
-
(2010)
Cell Cycle
, vol.9
, pp. 652-655
-
-
Neufert, C.1
-
113
-
-
84904243497
-
Expression of interleukin (IL)-19 and IL-24 in inflammatory bowel disease patients: A cross-sectional study
-
Fonseca-Camarillo, G., Furuzawa-Carballeda, J., Granados, J., Yamamoto-Furusho, J. K. Expression of interleukin (IL)-19 and IL-24 in inflammatory bowel disease patients: a cross-sectional study. Clin. Exp. Immunol. 177, 64-75 (2014).
-
(2014)
Clin. Exp. Immunol.
, vol.177
, pp. 64-75
-
-
Fonseca-Camarillo, G.1
Furuzawa-Carballeda, J.2
Granados, J.3
Yamamoto-Furusho, J.K.4
-
114
-
-
84879880293
-
IL-10-and IL-20-expressing epithelial and inflammatory cells are increased in patients with ulcerative colitis
-
Fonseca-Camarillo, G., Furuzawa-Carballeda, J., Llorente, L., Yamamoto-Furusho, J. K. IL-10-and IL-20-expressing epithelial and inflammatory cells are increased in patients with ulcerative colitis. J. Clin. Immunol. 33, 640-648 (2013).
-
(2013)
J. Clin. Immunol.
, vol.33
, pp. 640-648
-
-
Fonseca-Camarillo, G.1
Furuzawa-Carballeda, J.2
Llorente, L.3
Yamamoto-Furusho, J.K.4
-
115
-
-
68949122797
-
Expression of IL-24, an activator of the JAK1/STAT3/SOCS3 cascade, is enhanced in inflammatory bowel disease
-
Andoh, A. et al. Expression of IL-24, an activator of the JAK1/STAT3/SOCS3 cascade, is enhanced in inflammatory bowel disease. J. Immunol. 183, 687-695 (2009).
-
(2009)
J. Immunol.
, vol.183
, pp. 687-695
-
-
Andoh, A.1
-
116
-
-
77952716486
-
Interleukin-19 protects mice from innate-mediated colonic inflammation
-
Azuma, Y. T. et al. Interleukin-19 protects mice from innate-mediated colonic inflammation. Inflamm. Bowel Dis. 16, 1017-1028 (2010).
-
(2010)
Inflamm. Bowel Dis.
, vol.16
, pp. 1017-1028
-
-
Azuma, Y.T.1
-
117
-
-
44849111860
-
Expression of IL-19 and its receptors in RA: Potential role for synovial hyperplasia formation
-
Sakurai, N. et al. Expression of IL-19 and its receptors in RA: potential role for synovial hyperplasia formation. Rheumatol. 47, 815-820 (2008).
-
(2008)
Rheumatol
, vol.47
, pp. 815-820
-
-
Sakurai, N.1
-
118
-
-
17244381180
-
Expression of interleukin-22 in rheumatoid arthritis: Potential role as a proinflammatory cytokine
-
Ikeuchi, H. et al. Expression of interleukin-22 in rheumatoid arthritis: potential role as a proinflammatory cytokine. Arthritis Rheum. 52, 1037-1046 (2005).
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1037-1046
-
-
Ikeuchi, H.1
-
119
-
-
37449013636
-
The expression of IL-20 and IL-24 and their shared receptors are increased in rheumatoid arthritis and spondyloarthropathy
-
Kragstrup, T. W. et al. The expression of IL-20 and IL-24 and their shared receptors are increased in rheumatoid arthritis and spondyloarthropathy. Cytokine 41, 16-23 (2008).
-
(2008)
Cytokine
, vol.41
, pp. 16-23
-
-
Kragstrup, T.W.1
-
120
-
-
84866714220
-
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation
-
Corvaisier, M. et al. IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. PLoS Biol. 10, e1001395 (2012).
-
(2012)
PLoS Biol
, vol.10
, pp. e1001395
-
-
Corvaisier, M.1
-
121
-
-
77950243426
-
Expression of IL-10 family cytokines in rheumatoid arthritis: Elevated levels of IL-19 in the joints
-
Alanara, T., Karstila, K., Moilanen, T., Silvennoinen, O., Isomaki, P. Expression of IL-10 family cytokines in rheumatoid arthritis: elevated levels of IL-19 in the joints. Scand. J. Rheumatol 39, 118-126 (2010).
-
(2010)
Scand. J. Rheumatol
, vol.39
, pp. 118-126
-
-
Alanara, T.1
Karstila, K.2
Moilanen, T.3
Silvennoinen, O.4
Isomaki, P.5
-
122
-
-
33749320939
-
Function of interleukin-20 as a proinflammatory molecule in rheumatoid and experimental arthritis
-
Hsu, Y.-H. et al. Function of interleukin-20 as a proinflammatory molecule in rheumatoid and experimental arthritis. Arthritis Rheum. 54, 2722-2733 (2006).
-
(2006)
Arthritis Rheum
, vol.54
, pp. 2722-2733
-
-
Hsu, Y.-H.1
-
123
-
-
47249125726
-
Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes
-
P?ne, J. et al. Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes. J. Immunol. 180, 7423-7430 (2008).
-
(2008)
J. Immunol.
, vol.180
, pp. 7423-7430
-
-
Pne, J.1
-
124
-
-
66449133523
-
Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis
-
Shen, H., Goodall, J. C., Hill Gaston, J. S. Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis. Arthritis Rheum. 60, 1647-1656 (2009).
-
(2009)
Arthritis Rheum
, vol.60
, pp. 1647-1656
-
-
Shen, H.1
Goodall, J.C.2
Hill Gaston, J.S.3
-
125
-
-
79959811817
-
Interleukin 22 serum levels are associated with radiographic progression in rheumatoid arthritis
-
Leipe, J. et al. Interleukin 22 serum levels are associated with radiographic progression in rheumatoid arthritis. Ann. Rheum. Dis. 70, 1453-1457 (2011).
-
(2011)
Ann. Rheum. Dis.
, vol.70
, pp. 1453-1457
-
-
Leipe, J.1
-
126
-
-
84859237495
-
Increased frequencies of Th22 cells as well as Th17 cells in the peripheral blood of patients with ankylosing spondylitis and rheumatoid arthritis
-
Zhang, L. et al. Increased frequencies of Th22 cells as well as Th17 cells in the peripheral blood of patients with ankylosing spondylitis and rheumatoid arthritis. PLoS ONE 7, e31000 (2012).
-
(2012)
PLoS ONE
, vol.7
, pp. e31000
-
-
Zhang, L.1
-
127
-
-
84857551794
-
Interleukin-19 blockade attenuates collagen-induced arthritis in rats
-
Hsu, Y. H., Hsieh, P. P., Chang, M. S. Interleukin-19 blockade attenuates collagen-induced arthritis in rats. Rheumatol. 51, 434-442 (2012).
-
(2012)
Rheumatol
, vol.51
, pp. 434-442
-
-
Hsu, Y.H.1
Hsieh, P.P.2
Chang, M.S.3
-
128
-
-
80555150814
-
Elevated Th22 cells correlated with Th17 cells in patients with rheumatoid arthritis
-
Zhang, L. et al. Elevated Th22 cells correlated with Th17 cells in patients with rheumatoid arthritis. J. Clin. Immunol. 31, 606-614 (2011).
-
(2011)
J. Clin. Immunol.
, vol.31
, pp. 606614
-
-
Zhang, L.1
-
129
-
-
84863507522
-
Increased serum interleukin 22 in patients with rheumatoid arthritis and correlation with disease activity
-
da Rocha, L. F. et al. Increased serum interleukin 22 in patients with rheumatoid arthritis and correlation with disease activity. J. Rheumatol. 39, 1320-1325 (2012).
-
(2012)
J. Rheumatol.
, vol.39
, pp. 1320-1325
-
-
Da Rocha, L.F.1
-
130
-
-
59649086053
-
Proinflammatory role of the Th17 cytokine interleukin-22 in collagen-induced arthritis in C57BL/6 mice
-
Geboes, L. et al. Proinflammatory role of the Th17 cytokine interleukin-22 in collagen-induced arthritis in C57BL/6 mice. Arthritis Rheum. 60, 390-395 (2009).
-
(2009)
Arthritis Rheum
, vol.60
, pp. 390-395
-
-
Geboes, L.1
-
131
-
-
84899835126
-
Endogenous IL-22 plays a dual role in arthritis: Regulation of established arthritis via IFN- responses
-
Justa, S., Zhou, X., Sarkar, S. Endogenous IL-22 plays a dual role in arthritis: regulation of established arthritis via IFN- responses. PLoS ONE 9, e93279 (2014).
-
(2014)
PLoS ONE
, vol.9
, pp. e93279
-
-
Justa, S.1
Zhou, X.2
Sarkar, S.3
-
132
-
-
80053510122
-
Increased expression of interleukin-22 by synovial Th17 cells during late stages of murine experimental arthritis is controlled by interleukin-1 and enhances bone degradation
-
Marijnissen, R. J. et al. Increased expression of interleukin-22 by synovial Th17 cells during late stages of murine experimental arthritis is controlled by interleukin-1 and enhances bone degradation. Arthritis Rheum. 63, 2939-2948 (2011).
-
(2011)
Arthritis Rheum
, vol.63
, Issue.2939-2948
-
-
Marijnissen, R.J.1
-
133
-
-
84863697312
-
IL-23 induces spondyloarthropathy by acting on ROR-?t+ CD3+CD4-CD8-entheseal resident T cells
-
Sherlock, J. P. et al. IL-23 induces spondyloarthropathy by acting on ROR-?t+ CD3+CD4-CD8-entheseal resident T cells. Nature Med. 18, 1069-1076 (2012).
-
(2012)
Nature Med
, vol.18
, pp. 1069-1076
-
-
Sherlock, J.P.1
-
134
-
-
84903473100
-
IL-23-mediates the intestinal response to microbial ?-glucan and the development of spondyloarthritis pathology in SKG mice
-
Benham, H. et al. IL-23-mediates the intestinal response to microbial ?-glucan and the development of spondyloarthritis pathology in SKG mice. Arthritis Rheumatol. 66, 1755-1767 (2014).
-
(2014)
Arthritis Rheumatol
, vol.66
, pp. 1755-1767
-
-
Benham, H.1
-
135
-
-
84884573774
-
Th17 and Th22 cells in psoriatic arthritis and psoriasis
-
Benham, H. et al. Th17 and Th22 cells in psoriatic arthritis and psoriasis. Arthritis Res. Ther. 15, R136 (2013).
-
(2013)
Arthritis Res. Ther.
, vol.15
, pp. R136
-
-
Benham, H.1
-
136
-
-
0029834058
-
Aetiology and pathogenesis of psoriasis
-
Ortonne, J. P. Aetiology and pathogenesis of psoriasis. Br. J. Dermatol. 135 (Suppl. 49), 1-5 (1996).
-
(1996)
Br. J. Dermatol.
, vol.135
, pp. 1-5
-
-
Ortonne, J.P.1
-
137
-
-
13444269249
-
Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model
-
Sano, S. et al. Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model. Nature Med. 11, 43-49 (2005).
-
(2005)
Nature Med
, vol.11
, pp. 43-49
-
-
Sano, S.1
-
138
-
-
84877828212
-
Interleukin (IL)-19 promoted skin wound healing by increasing fibroblast keratinocyte growth factor expression
-
Sun, D. P. et al. Interleukin (IL)-19 promoted skin wound healing by increasing fibroblast keratinocyte growth factor expression. Cytokine 62, 360-368 (2013).
-
(2013)
Cytokine
, vol.62
, pp. 360-368
-
-
Sun, D.P.1
-
139
-
-
84876681730
-
IL-22 promotes fibroblast-mediated wound repair in the skin
-
McGee, H. M. et al. IL-22 promotes fibroblast-mediated wound repair in the skin. J. Invest. Dermatol. 133, 1321-1329 (2013)
-
(2013)
J. Invest. Dermatol.
, vol.133
, pp. 1321-1329
-
-
McGee, H.M.1
-
140
-
-
77954851839
-
IL-24 is expressed during wound repair and inhibits TGF?-induced migration and proliferation of keratinocytes
-
Poindexter, N. J. et al. IL-24 is expressed during wound repair and inhibits TGF?-induced migration and proliferation of keratinocytes. Exp. Dermatol. 19, 714-722 (2010).
-
(2010)
Exp. Dermatol.
, vol.19
, pp. 714-722
-
-
Poindexter, N.J.1
-
141
-
-
64849116779
-
The role of vascular endothelial growth factor in wound healing
-
Bao, P. et al. The role of vascular endothelial growth factor in wound healing. J. Surg. Res. 153, 347-358 (2009).
-
(2009)
J. Surg. Res.
, vol.153
, pp. 347-358
-
-
Bao, P.1
-
142
-
-
84896385770
-
Integrative biology approach identifies cytokine targeting strategies for psoriasis
-
Perera, G. K. et al. Integrative biology approach identifies cytokine targeting strategies for psoriasis. Sci. Transl. Med. 6, 223ra22 (2014).
-
(2014)
Sci. Transl. Med.
, vol.6
, pp. 223ra22
-
-
Perera, G.K.1
-
143
-
-
84865401664
-
Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease
-
Hanash, A. M. et al. Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease. Immunity 37, 339-350 (2012).
-
(2012)
Immunity
, vol.37
, pp. 339-350
-
-
Hanash, A.M.1
-
144
-
-
2342462460
-
Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation
-
Radaeva, S., Sun, R., Pan, H. N., Hong, F., Gao, B. Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation. Hepatology 39, 1332-1342 (2004).
-
(2004)
Hepatology
, vol.39
, pp. 1332-1342
-
-
Radaeva, S.1
Sun, R.2
Pan, H.N.3
Hong, F.4
Gao, B.5
-
145
-
-
35348983341
-
Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation
-
Zenewicz, L. A. et al. Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation. Immunity 27, 647-659 (2007).
-
(2007)
Immunity
, vol.27
, pp. 647-659
-
-
Zenewicz, L.A.1
-
146
-
-
2342458559
-
Hydrodynamic gene delivery of interleukin-22 protects the mouse liver from concanavalin A-, carbon tetrachloride-, and Fas ligand-induced injury via activation of STAT3
-
Pan, H., Hong, F., Radaeva, S., Gao, B. Hydrodynamic gene delivery of interleukin-22 protects the mouse liver from concanavalin A-, carbon tetrachloride-, and Fas ligand-induced injury via activation of STAT3. Cell. Mol. Immunol. 1, 43-49 (2004).
-
(2004)
Cell. Mol. Immunol.
, vol.1
, pp. 43-49
-
-
Pan, H.1
Hong, F.2
Radaeva, S.3
Gao, B.4
-
147
-
-
79955776494
-
In vivo consequences of liver-specific interleukin-22 expression in mice: Implications for human liver disease progression
-
Park, O. et al. In vivo consequences of liver-specific interleukin-22 expression in mice: implications for human liver disease progression. Hepatology 54, 252-261 (2011).
-
(2011)
Hepatology
, vol.54
, pp. 252-261
-
-
Park, O.1
-
148
-
-
77957946415
-
Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: Role of signal transducer and activator of transcription 3
-
Ki, S. H. et al. Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: role of signal transducer and activator of transcription 3. Hepatology 52, 1291-1300 (2010).
-
(2010)
Hepatology
, vol.52
, pp. 1291-1300
-
-
Ki, S.H.1
-
149
-
-
84865564349
-
Interleukin-22 induces hepatic stellate cell senescence and restricts liver fibrosis in mice
-
Kong, X. et al. Interleukin-22 induces hepatic stellate cell senescence and restricts liver fibrosis in mice. Hepatology 56, 1150-1159 (2012).
-
(2012)
Hepatology
, vol.56
, pp. 1150-1159
-
-
Kong, X.1
-
151
-
-
84869754821
-
Aryl hydrocarbon receptor regulates pancreatic IL-22 production and protects mice from acute pancreatitis
-
Xue, J., Nguyen, D. T., Habtezion, A. Aryl hydrocarbon receptor regulates pancreatic IL-22 production and protects mice from acute pancreatitis. Gastroenterology 143, 1670-1680 (2012).
-
(2012)
Gastroenterology
, vol.143
, pp. 1670-1680
-
-
Xue, J.1
Nguyen, D.T.2
Habtezion, A.3
-
152
-
-
84862915680
-
Interleukin-22 ameliorates cerulein-induced pancreatitis in mice by inhibiting the autophagic pathway
-
Feng, D. et al. Interleukin-22 ameliorates cerulein-induced pancreatitis in mice by inhibiting the autophagic pathway. Int. J. Biol. Sci. 8, 249-257 (2012).
-
(2012)
Int. J. Biol. Sci.
, vol.8
, pp. 249-257
-
-
Feng, D.1
-
153
-
-
84906539304
-
Toll-like receptor 4-induced IL-22 accelerates kidney regeneration
-
Kulkarni, O. P. et al. Toll-like receptor 4-induced IL-22 accelerates kidney regeneration. J. Am. Soc. Nephrol. 25, 978-989 (2014).
-
(2014)
J. Am. Soc. Nephrol.
, vol.25
, pp. 978-989
-
-
Kulkarni, O.P.1
-
154
-
-
84902109613
-
IL-22 ameliorates renal ischemia-reperfusion injury by targeting proximal tubule epithelium
-
Xu, M. J. et al. IL-22 ameliorates renal ischemia-reperfusion injury by targeting proximal tubule epithelium. J. Am. Soc. Nephrol. 25, 967-977 (2014).
-
(2014)
J. Am. Soc. Nephrol.
, vol.25
, pp. 967-977
-
-
Xu, M.J.1
-
155
-
-
84859497086
-
Interleukin-22 drives endogenous thymic regeneration in mice
-
Dudakov, J. A. et al. Interleukin-22 drives endogenous thymic regeneration in mice. Science 336, 91-95 (2012).
-
(2012)
Science
, vol.336
, pp. 91-95
-
-
Dudakov, J.A.1
-
156
-
-
84874485590
-
Interleukin-19 mediates tissue damage in murine ischemic acute kidney injury
-
Hsu, Y. H. et al. Interleukin-19 mediates tissue damage in murine ischemic acute kidney injury. PLoS ONE 8, e56028 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e56028
-
-
Hsu, Y.H.1
-
157
-
-
84906940502
-
IL-20 and IL-20R1 antibodies protect against liver fibrosis
-
Chiu, Y. S., Wei, C. C., Lin, Y. J., Hsu, Y. H., Chang, M. S. IL-20 and IL-20R1 antibodies protect against liver fibrosis. Hepatology 60, 1003-1014 (2014).
-
(2014)
Hepatology
, vol.60
, pp. 1003-1014
-
-
Chiu, Y.S.1
Wei, C.C.2
Lin, Y.J.3
Hsu, Y.H.4
Chang, M.S.5
-
158
-
-
84863165532
-
Anti-IL-20 monoclonal antibody suppresses breast cancer progression and bone osteolysis in murine models
-
Hsu, Y. H. et al. Anti-IL-20 monoclonal antibody suppresses breast cancer progression and bone osteolysis in murine models. J. Immunol. 188, 1981-1991 (2012).
-
(2012)
J. Immunol.
, vol.188
, pp. 1981-1991
-
-
Hsu, Y.H.1
-
159
-
-
80051490289
-
IL-20 is epigenetically regulated in NSCLC and down regulates the expression of VEGF
-
Baird, A. M., Gray, S. G., O'Byrne, K. J. IL-20 is epigenetically regulated in NSCLC and down regulates the expression of VEGF. Eur. J. Cancer 47, 1908-1918 (2011).
-
(2011)
Eur. J. Cancer
, vol.47
, pp. 1908-1918
-
-
Baird, A.M.1
Gray, S.G.2
O'Byrne, K.J.3
-
160
-
-
84869228833
-
Anti-IL-20 monoclonal antibody alleviates inflammation in oral cancer and suppresses tumor growth
-
Hsu, Y. H., Wei, C. C., Shieh, D. B., Chan, C. H., Chang, M. S. Anti-IL-20 monoclonal antibody alleviates inflammation in oral cancer and suppresses tumor growth. Mol. Cancer Res. 10, 1430-1439 (2012).
-
(2012)
Mol. Cancer Res.
, vol.10
, pp. 1430-1439
-
-
Hsu, Y.H.1
Wei, C.C.2
Shieh, D.B.3
Chan, C.H.4
Chang, M.S.5
-
161
-
-
84874343878
-
Interleukin-20 promotes migration of bladder cancer cells through extracellular signal-regulated kinase (ERK)-mediated MMP-9 protein expression leading to nuclear factor (NF-?B) activation by inducing the up-regulation of p21WAF1 protein expression
-
Lee, S. J. et al. Interleukin-20 promotes migration of bladder cancer cells through extracellular signal-regulated kinase (ERK)-mediated MMP-9 protein expression leading to nuclear factor (NF-?B) activation by inducing the up-regulation of p21WAF1 protein expression. J. Biol. Chem. 288, 5539-5552 (2013).
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 5539-5552
-
-
Lee, S.J.1
-
162
-
-
84866010102
-
Identification of pro-inflammatory cytokines associated with muscle invasive bladder cancer; The roles of IL-5 IL-20, and IL-28A
-
Lee, S. J. et al. Identification of pro-inflammatory cytokines associated with muscle invasive bladder cancer; the roles of IL-5, IL-20, and IL-28A. PLoS ONE 7, e40267 (2012).
-
(2012)
PLoS ONE
, vol.7
, pp. e40267
-
-
Lee, S.J.1
-
163
-
-
8444223078
-
Expression of interleukin-22 in murine carcinoma cells did not influence tumour growth in vivo but did improve survival of the inoculated hosts
-
Nagakawa, H. et al. Expression of interleukin-22 in murine carcinoma cells did not influence tumour growth in vivo but did improve survival of the inoculated hosts. Scand. J. Immunol. 60, 449-454 (2004).
-
(2004)
Scand. J. Immunol.
, vol.60
, pp. 449-454
-
-
Nagakawa, H.1
-
164
-
-
84891674362
-
High expression of interleukin-22 and its receptor predicts poor prognosis in pancreatic ductal adenocarcinoma
-
Wen, Z. et al. High expression of interleukin-22 and its receptor predicts poor prognosis in pancreatic ductal adenocarcinoma. Ann. Surg. Oncol. 21, 125-132 (2014).
-
(2014)
Ann. Surg. Oncol.
, vol.21
, pp. 125-132
-
-
Wen, Z.1
-
165
-
-
84902077790
-
The role of the IL-22/IL-22R1 axis in cancer
-
Lim, C., Savan, R. The role of the IL-22/IL-22R1 axis in cancer. Cytokine Growth Factor Rev. 25, 257-271 (2014).
-
(2014)
Cytokine Growth Factor Rev
, vol.25
, pp. 257-271
-
-
Lim, C.1
Savan, R.2
-
166
-
-
66149138884
-
Historical perspective and recent insights into our understanding of the molecular and biochemical basis of the antitumor properties of mda-7/IL-24
-
Emdad, L. et al. Historical perspective and recent insights into our understanding of the molecular and biochemical basis of the antitumor properties of mda-7/IL-24. Cancer Biol. Ther. 8, 391-400 (2009).
-
(2009)
Cancer Biol. Ther.
, vol.8
, pp. 391-400
-
-
Emdad, L.1
-
167
-
-
84869864406
-
Interleukin 24: Mechanisms and therapeutic potential of an anti-cancer gene
-
Whitaker, E. L., Filippov, V. A., Duerksen-Hughes, P. J. Interleukin 24: mechanisms and therapeutic potential of an anti-cancer gene. Cytokine Growth Factor Rev. 23, 323-331 (2012).
-
(2012)
Cytokine Growth Factor Rev
, vol.23
, pp. 323-331
-
-
Whitaker, E.L.1
Filippov, V.A.2
Duerksen-Hughes, P.J.3
-
168
-
-
57149138049
-
IL-24: A classic cytokine and/or a potential cure for cancer? J
-
Kreis, S., Philippidou, D., Margue, C., Behrmann, I. IL-24: a classic cytokine and/or a potential cure for cancer? J. Cell. Mol. Med. 16, 2505-2510 (2008).
-
(2008)
Cell. Mol. Med.
, vol.16
, pp. 2505-2510
-
-
Kreis, S.1
Philippidou, D.2
Margue, C.3
Behrmann, I.4
-
169
-
-
44949199373
-
Recombinant interleukin-24 lacks apoptosis-inducing properties in melanoma cells
-
Kreis, S. et al. Recombinant interleukin-24 lacks apoptosis-inducing properties in melanoma cells. PLoS ONE 2, e1300 (2007).
-
(2007)
PLoS ONE
, vol.2
, pp. e1300
-
-
Kreis, S.1
-
170
-
-
70350500225
-
STATs in cancer inflammation and immunity: A leading role for STAT3
-
Yu, H., Pardoll, D., Jove, R. STATs in cancer inflammation and immunity: a leading role for STAT3. Nature Rev. Cancer 9, 798-809 (2009).
-
(2009)
Nature Rev. Cancer
, vol.9
, pp. 798-809
-
-
Yu, H.1
Pardoll, D.2
Jove, R.3
-
171
-
-
77249098774
-
Stat3 is a negative regulator of intestinal tumor progression in ApcMin mice
-
1-5
-
Musteanu, M. et al. Stat3 is a negative regulator of intestinal tumor progression in ApcMin mice. Gastroenterology 138, 1003-1011.e1-5 (2010).
-
(2010)
Gastroenterology
, vol.138
, pp. 1003-1011
-
-
Musteanu, M.1
-
172
-
-
84878003390
-
IL-26 promotes the proliferation and survival of human gastric cancer cells by regulating the balance of STAT1 and STAT3 activation
-
You, W. et al. IL-26 promotes the proliferation and survival of human gastric cancer cells by regulating the balance of STAT1 and STAT3 activation. PLoS ONE 8, e63588 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e63588
-
-
You, W.1
-
173
-
-
46749127004
-
DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice
-
Meira, L. B. et al. DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice. J. Clin. Invest. 118, 2516-2525 (2008).
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 2516-2525
-
-
Meira, L.B.1
-
174
-
-
84879571464
-
Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model
-
Kirchberger, S. et al. Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model. J. Exp. Med. 210, 917-931 (2013).
-
(2013)
J. Exp. Med.
, vol.210
, pp. 917-931
-
-
Kirchberger, S.1
-
175
-
-
77955308513
-
Amelioration of high fat diet induced liver lipogenesis and hepatic steatosis by interleukin-22
-
Yang, L. et al. Amelioration of high fat diet induced liver lipogenesis and hepatic steatosis by interleukin-22. J. Hepatol. 53, 339-347 (2010)
-
(2010)
J. Hepatol.
, vol.53
, pp. 339-347
-
-
Yang, L.1
-
176
-
-
84864118287
-
Immunological complications of obesity
-
Kanneganti, T. D., Dixit, V. D. Immunological complications of obesity. Nature Immunol. 13, 707-712 (2012).
-
(2012)
Nature Immunol
, vol.13
, pp. 707-712
-
-
Kanneganti, T.D.1
Dixit, V.D.2
-
177
-
-
11144357516
-
Role of STAT-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism in vivo
-
Inoue, H. et al. Role of STAT-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism in vivo. Nature Med. 10, 168-174 (2004).
-
(2004)
Nature Med
, vol.10
, pp. 168-174
-
-
Inoue, H.1
-
178
-
-
77950250064
-
Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5
-
Vijay-Kumar, M. et al. Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5. Science 328, 228-231 (2010).
-
(2010)
Science
, vol.328
, pp. 228-231
-
-
Vijay-Kumar, M.1
-
179
-
-
84908311821
-
Interleukin-22 alleviates metabolic disorders and restores mucosal immunity in diabetes
-
Wang, X. et al. Interleukin-22 alleviates metabolic disorders and restores mucosal immunity in diabetes. Nature 514, 237-241 (2014).
-
(2014)
Nature
, vol.514
, pp. 237-241
-
-
Wang, X.1
-
180
-
-
17644412023
-
Inflammation atherosclerosis, and coronary artery disease
-
Hansson, G. K. Inflammation, atherosclerosis, and coronary artery disease. N. Engl. J. Med. 352, 1685-1695 (2005).
-
(2005)
N. Engl. J. Med.
, vol.352
, pp. 1685-1695
-
-
Hansson, G.K.1
-
181
-
-
67449110958
-
Association of psoriasis with coronary artery, cerebrovascular, and peripheral vascular diseases and mortality
-
Prodanovich, S. et al. Association of psoriasis with coronary artery, cerebrovascular, and peripheral vascular diseases and mortality. Arch. Dermatol. 145, 700-703 (2009).
-
(2009)
Arch. Dermatol.
, vol.145
, pp. 700-703
-
-
Prodanovich, S.1
-
182
-
-
84885070573
-
Attenuation of experimental atherosclerosis by interleukin-19
-
Ellison, S. et al. Attenuation of experimental atherosclerosis by interleukin-19. Arterioscler Thromb. Vasc. Biol. 33, 2316-2324 (2013).
-
(2013)
Arterioscler Thromb. Vasc. Biol.
, vol.33
, pp. 2316-2324
-
-
Ellison, S.1
-
183
-
-
33747431572
-
IL-20 is expressed in atherosclerosis plaques and promotes atherosclerosis in apolipoprotein E-deficient mice. Arteriosclerosis
-
Chen, W. Y., Cheng, B. C., Jiang, M. J., Hsieh, M. Y., Chang, M. S. IL-20 is expressed in atherosclerosis plaques and promotes atherosclerosis in apolipoprotein E-deficient mice. Arteriosclerosis, Thromb. Vascular Biol. 26, 2090-2095 (2006).
-
(2006)
Thromb. Vascular Biol.
, vol.26
, pp. 2090-2095
-
-
Chen, W.Y.1
Cheng, B.C.2
Jiang, M.J.3
Hsieh, M.Y.4
Chang, M.S.5
-
184
-
-
84877839153
-
IL-22 deficiency alters colonic microbiota to be transmissible and colitogenic
-
Zenewicz, L. A. et al. IL-22 deficiency alters colonic microbiota to be transmissible and colitogenic. J. Immunol. 190, 5306-5312 (2013).
-
(2013)
J. Immunol.
, vol.190
, pp. 5306-5312
-
-
Zenewicz, L.A.1
-
185
-
-
70349742524
-
The key role of segmented filamentous bacteria in the coordinated maturation of gut helper T cell responses
-
Gaboriau-Routhiau, V. et al. The key role of segmented filamentous bacteria in the coordinated maturation of gut helper T cell responses. Immunity 31, 677-689 (2009).
-
(2009)
Immunity
, vol.31
, pp. 677-689
-
-
Gaboriau-Routhiau, V.1
-
186
-
-
70350343544
-
Induction of intestinal Th17 cells by segmented filamentous bacteria
-
Ivanov, I. I. et al. Induction of intestinal Th17 cells by segmented filamentous bacteria. Cell 139, 485-498 (2009).
-
(2009)
Cell
, vol.139
, pp. 485-498
-
-
Ivanov, I.I.1
-
187
-
-
77953913586
-
Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells
-
Wu, H.-J. et al. Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells. Immunity 32, 815-827 (2010).
-
(2010)
Immunity
, vol.32
, pp. 815-827
-
-
Wu, H.-J.1
-
188
-
-
79952748674
-
Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis
-
Lee, Y. K., Menezes, J. S., Umesaki, Y., Mazmanian, S. K. Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis. Proc. Natl Acad. Sci. USA 108 (Suppl. 1), 4615-4622 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 4615-4622
-
-
Lee, Y.K.1
Menezes, J.S.2
Umesaki, Y.3
Mazmanian, S.K.4
-
189
-
-
84882668842
-
Group 3 innate lymphoid cells inhibit T-cell-mediated intestinal inflammation through aryl hydrocarbon receptor signaling and regulation of microflora
-
Qiu, J. et al. Group 3 innate lymphoid cells inhibit T-cell-mediated intestinal inflammation through aryl hydrocarbon receptor signaling and regulation of microflora. Immunity 39, 386-399 (2013).
-
(2013)
Immunity
, vol.39
, pp. 386-399
-
-
Qiu, J.1
-
190
-
-
84866547629
-
Lymphotoxin regulates commensal responses to enable diet-induced obesity
-
Upadhyay, V. et al. Lymphotoxin regulates commensal responses to enable diet-induced obesity. Nature Immunol. 13, 947-953 (2012).
-
(2012)
Nature Immunol
, vol.13
, pp. 947-953
-
-
Upadhyay, V.1
|