-
2
-
-
84884311983
-
Major histocompatibility complex genomics and human disease
-
Trowsdale, J. & Knight, J. C. Major histocompatibility complex genomics and human disease. Ann. Rev. Genom. Hum. Genet. 14, 301-323 (2013).
-
(2013)
Ann. Rev. Genom. Hum. Genet.
, vol.14
, pp. 301-323
-
-
Trowsdale, J.1
Knight, J.C.2
-
3
-
-
84944881339
-
The burgeoning family of unconventional T cells
-
Godfrey, D. I., Uldrich, A. P., McCluskey, J., Rossjohn, J. & Moody, D. B. The burgeoning family of unconventional T cells. Nat. Immunol. 16, 1114-1123 (2015).
-
(2015)
Nat. Immunol.
, vol.16
, pp. 1114-1123
-
-
Godfrey, D.I.1
Uldrich, A.P.2
McCluskey, J.3
Rossjohn, J.4
Moody, D.B.5
-
4
-
-
84956609076
-
The IPD-IMGT/HLA database-new developments in reporting HLA variation
-
Robinson, J., Soormally, A. R., Hayhurst, J. D. & Marsh, S. G. E. The IPD-IMGT/HLA database-new developments in reporting HLA variation. Hum. Immunol. 77, 233-237 (2016).
-
(2016)
Hum. Immunol.
, vol.77
, pp. 233-237
-
-
Robinson, J.1
Soormally, A.R.2
Hayhurst, J.D.3
Marsh, S.G.E.4
-
5
-
-
0030006049
-
Population biology of antigen presentation by MHC class i molecules
-
Parham, P. & Ohta, T. Population biology of antigen presentation by MHC class I molecules. Science 272, 67-74 (1996).
-
(1996)
Science
, vol.272
, pp. 67-74
-
-
Parham, P.1
Ohta, T.2
-
6
-
-
0033548497
-
HLA and HIV?1: Heterozygote advantage and B35?Cw04 disadvantage
-
Carrington, M. et al. HLA and HIV?1: heterozygote advantage and B35?Cw04 disadvantage. Science 283, 1748-1752 (1999).
-
(1999)
Science
, vol.283
, pp. 1748-1752
-
-
Carrington, M.1
-
7
-
-
84872920040
-
Variable NK cell receptors and their MHC class i ligands in immunity, reproduction and human evolution
-
Parham, P. & Moffett, A. Variable NK cell receptors and their MHC class I ligands in immunity, reproduction and human evolution. Nat. Rev. Immunol. 13, 133-144 (2013).
-
(2013)
Nat. Rev. Immunol.
, vol.13
, pp. 133-144
-
-
Parham, P.1
Moffett, A.2
-
8
-
-
84866419166
-
Why must T cells be cross-reactive?
-
Sewell, A. K. Why must T cells be cross-reactive? Nat. Rev. Immunol. 12, 668-677 (2012).
-
(2012)
Nat. Rev. Immunol.
, vol.12
, pp. 668-677
-
-
Sewell, A.K.1
-
9
-
-
78650596159
-
Convergent recombination shapes the clonotypic landscape of the naive T?cell repertoire
-
Quigley, M. F. et al. Convergent recombination shapes the clonotypic landscape of the naive T?cell repertoire. Proc. Natl Acad. Sci. USA 107, 19414-19419 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 19414-19419
-
-
Quigley, M.F.1
-
10
-
-
84939510299
-
A bird's eye view of NK cell receptor interactions with their MHC class i ligands
-
Saunders, P. M. et al. A bird's eye view of NK cell receptor interactions with their MHC class I ligands. Immunol. Rev. 267, 148-166 (2015).
-
(2015)
Immunol. Rev.
, vol.267
, pp. 148-166
-
-
Saunders, P.M.1
-
11
-
-
84984617553
-
Leukocyte Ig-Like Receptors-A model for MHC class i disease associations
-
Hudson, L. E. & Allen, R. L. Leukocyte Ig?Like Receptors-a model for MHC class I disease associations. Front. Immunol. 7, 281 (2016).
-
(2016)
Front. Immunol.
, vol.7
, pp. 281
-
-
Hudson, L.E.1
Allen, R.L.2
-
12
-
-
77953414590
-
Peptide antagonism as a mechanism for NK cell activation
-
Fadda, L. et al. Peptide antagonism as a mechanism for NK cell activation. Proc. Natl Acad. Sci. USA 107, 10160-10165 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 10160-10165
-
-
Fadda, L.1
-
13
-
-
85017167240
-
Canonical and cross-reactive binding of NK cell inhibitory receptors to HLA?C allotypes is dictated by peptides bound to HLA?C
-
Sim, M. J. et al. Canonical and cross-reactive binding of NK cell inhibitory receptors to HLA?C allotypes is dictated by peptides bound to HLA?C. Front. Immunol. 8, 193 (2017).
-
(2017)
Front. Immunol.
, vol.8
, pp. 193
-
-
Sim, M.J.1
-
14
-
-
84929950810
-
Understanding the complexity and malleability of T?cell recognition
-
Miles, J. J., McCluskey, J., Rossjohn, J. & Gras, S. Understanding the complexity and malleability of T?cell recognition. Immunol. Cell Biol. 93, 433-441 (2015).
-
(2015)
Immunol. Cell Biol.
, vol.93
, pp. 433-441
-
-
Miles, J.J.1
McCluskey, J.2
Rossjohn, J.3
Gras, S.4
-
15
-
-
0032719206
-
A humanized model for multiple sclerosis using HLA?DR2 and a human T?cell receptor
-
Madsen, L. S. et al. A humanized model for multiple sclerosis using HLA?DR2 and a human T?cell receptor. Nat. Genet. 23, 343-347 (1999).
-
(1999)
Nat. Genet.
, vol.23
, pp. 343-347
-
-
Madsen, L.S.1
-
16
-
-
18244392426
-
Unconventional topology of self peptide-major histocompatibility complex binding by a human autoimmune T cell receptor
-
Hahn, M., Nicholson, M. J., Pyrdol, J. & Wucherpfennig, K. W. Unconventional topology of self peptide-major histocompatibility complex binding by a human autoimmune T cell receptor. Nat. Immunol. 6, 490-496 (2005).
-
(2005)
Nat. Immunol.
, vol.6
, pp. 490-496
-
-
Hahn, M.1
Nicholson, M.J.2
Pyrdol, J.3
Wucherpfennig, K.W.4
-
17
-
-
84857189975
-
Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes
-
Bulek, A. M. et al. Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes. Nat. Immunol. 13, 283-289 (2012).
-
(2012)
Nat. Immunol.
, vol.13
, pp. 283-289
-
-
Bulek, A.M.1
-
18
-
-
18244421874
-
The insulin gene is transcribed in the human thymus and transcription levels correlate with allelic variation at the INS VNTR?IDDM2 susceptibility locus for type 1 diabetes
-
Pugliese, A. et al. The insulin gene is transcribed in the human thymus and transcription levels correlate with allelic variation at the INS VNTR?IDDM2 susceptibility locus for type 1 diabetes. Nat. Genet. 15, 293-297 (1997).
-
(1997)
Nat. Genet.
, vol.15
, pp. 293-297
-
-
Pugliese, A.1
-
19
-
-
84973164846
-
Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity
-
Cole, D. K. et al. Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity. J. Clin. Invest. 126, 2191-2204 (2016).
-
(2016)
J. Clin. Invest.
, vol.126
, pp. 2191-2204
-
-
Cole, D.K.1
-
20
-
-
79952750632
-
Structure of a TCR with high affinity for self-antigen reveals basis for escape from negative selection
-
Yin, Y., Li, Y., Kerzic, M. C., Martin, R. & Mariuzza, R. A. Structure of a TCR with high affinity for self-antigen reveals basis for escape from negative selection. EMBO J. 30, 1137-1148 (2011).
-
(2011)
EMBO J.
, vol.30
, pp. 1137-1148
-
-
Yin, Y.1
Li, Y.2
Kerzic, M.C.3
Martin, R.4
Mariuzza, R.A.5
-
21
-
-
3242800448
-
Unique clinical and pathological features in HLA?DRB10401?restricted MBP 111?129?specific humanized TCR transgenic mice
-
Quandt, J. A. et al. Unique clinical and pathological features in HLA?DRB10401?restricted MBP 111?129?specific humanized TCR transgenic mice. J. Exp. Med. 200, 223-234 (2004).
-
(2004)
J. Exp. Med.
, vol.200
, pp. 223-234
-
-
Quandt, J.A.1
-
22
-
-
54049111388
-
Conformational changes and flexibility in T?cell receptor recognition of peptide-MHC complexes
-
Armstrong, K. M., Piepenbrink, K. H. & Baker, B. M. Conformational changes and flexibility in T?cell receptor recognition of peptide-MHC complexes. Biochem. J. 415, 183-196 (2008).
-
(2008)
Biochem. J.
, vol.415
, pp. 183-196
-
-
Armstrong, K.M.1
Piepenbrink, K.H.2
Baker, B.M.3
-
23
-
-
77954643719
-
Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register
-
Stadinski, B. D. et al. Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register. Proc. Natl Acad. Sci. USA 107, 10978-10983 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 10978-10983
-
-
Stadinski, B.D.1
-
24
-
-
84907901062
-
Autoreactive T cells specific for insulin B:11?23 recognize a low-affinity peptide register in human subjects with autoimmune diabetes
-
Yang, J. et al. Autoreactive T cells specific for insulin B:11?23 recognize a low-affinity peptide register in human subjects with autoimmune diabetes. Proc. Natl Acad. Sci. USA 111, 14840-14845 (2014).
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. 14840-14845
-
-
Yang, J.1
-
25
-
-
85019263685
-
Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells
-
Ooi, J. D. et al. Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells. Nature 545, 243-247 (2017).
-
(2017)
Nature
, vol.545
, pp. 243-247
-
-
Ooi, J.D.1
-
26
-
-
61949241207
-
T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides
-
Harkiolaki, M. et al. T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides. Immunity 30, 348-357 (2009).
-
(2009)
Immunity
, vol.30
, pp. 348-357
-
-
Harkiolaki, M.1
-
27
-
-
78651519759
-
A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC
-
Sethi, D. K. et al. A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC. J. Exp. Med. 208, 91-102 (2011).
-
(2011)
J. Exp. Med.
, vol.208
, pp. 91-102
-
-
Sethi, D.K.1
-
28
-
-
0028926223
-
Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein
-
Wucherpfennig, K. W. & Strominger, J. L. Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein. Cell 80, 695-705 (1995).
-
(1995)
Cell
, vol.80
, pp. 695-705
-
-
Wucherpfennig, K.W.1
Strominger, J.L.2
-
29
-
-
84923285215
-
Environmental risk factors and multiple sclerosis: An umbrella review of systematic reviews and meta-analyses
-
Belbasis, L., Bellou, V., Evangelou, E., Ioannidis, J. P. A. & Tzoulaki, L. Environmental risk factors and multiple sclerosis: an umbrella review of systematic reviews and meta-analyses. Lancet Neurol. 14, 263-273 (2015).
-
(2015)
Lancet Neurol.
, vol.14
, pp. 263-273
-
-
Belbasis, L.1
Bellou, V.2
Evangelou, E.3
Ioannidis, J.P.A.4
Tzoulaki, L.5
-
30
-
-
84942981489
-
Class II HLA interactions modulate genetic risk for multiple sclerosis
-
Moutsianas, L. et al. Class II HLA interactions modulate genetic risk for multiple sclerosis. Nat. Genet. 47, 1107-1113 (2015).
-
(2015)
Nat. Genet.
, vol.47
, pp. 1107-1113
-
-
Moutsianas, L.1
-
31
-
-
63149116383
-
Effects of infectious mononucleosis and HLA?DRB115 in multiple sclerosis
-
Nielsen, T. R. et al. Effects of infectious mononucleosis and HLA?DRB115 in multiple sclerosis. Mult. Scler. J. 15, 431-436 (2009).
-
(2009)
Mult. Scler. J.
, vol.15
, pp. 431-436
-
-
Nielsen, T.R.1
-
32
-
-
0036793245
-
A functional and structural basis for TCR cross-reactivity in multiple sclerosis
-
Lang, H. L. E. et al. A functional and structural basis for TCR cross-reactivity in multiple sclerosis. Nat. Immunol. 3, 940-943 (2002).
-
(2002)
Nat. Immunol.
, vol.3
, pp. 940-943
-
-
Lang, H.L.E.1
-
33
-
-
84992699812
-
Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes
-
Babon, J. A. et al. Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes. Nat. Med. 22, 1482-1487 (2016).
-
(2016)
Nat. Med.
, vol.22
, pp. 1482-1487
-
-
Babon, J.A.1
-
34
-
-
84938423979
-
Coeliac disease and rheumatoid arthritis: Similar mechanisms, different antigens
-
Koning, F., Thomas, R., Rossjohn, J. & Toes, R. E. Coeliac disease and rheumatoid arthritis: similar mechanisms, different antigens. Nat. Rev. Rheumatol. 11, 450-461 (2015).
-
(2015)
Nat. Rev. Rheumatol.
, vol.11
, pp. 450-461
-
-
Koning, F.1
Thomas, R.2
Rossjohn, J.3
Toes, R.E.4
-
35
-
-
84888116736
-
A molecular basis for the association of the HLA?DRB1 locus, citrullination, and rheumatoid arthritis
-
Scally, S. W. et al. A molecular basis for the association of the HLA?DRB1 locus, citrullination, and rheumatoid arthritis. J. Exp. Med. 210, 2569-2582 (2013).
-
(2013)
J. Exp. Med.
, vol.210
, pp. 2569-2582
-
-
Scally, S.W.1
-
36
-
-
54549089744
-
Phosphorylation-dependent interaction between antigenic peptides and MHC class I: A molecular basis for the presentation of transformed self
-
Mohammed, F. et al. Phosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed self. Nat. Immunol. 9, 1236-1243 (2008).
-
(2008)
Nat. Immunol.
, vol.9
, pp. 1236-1243
-
-
Mohammed, F.1
-
37
-
-
27744524215
-
The insulin A?chain epitope recognized by human T cells is posttranslationally modified
-
Mannering, S. I. et al. The insulin A?chain epitope recognized by human T cells is posttranslationally modified. J. Exp. Med. 202, 1191-1197 (2005).
-
(2005)
J. Exp. Med.
, vol.202
, pp. 1191-1197
-
-
Mannering, S.I.1
-
38
-
-
0031779478
-
Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease
-
Molberg, O. et al. Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease. Nat. Med. 4, 713-717 (1998).
-
(1998)
Nat. Med.
, vol.4
, pp. 713-717
-
-
Molberg, O.1
-
39
-
-
84857634950
-
T?Cell response to gluten in patients with HLA?DQ2. 2 reveals requirement of peptide-MHC stability in celiac disease
-
Bodd, M., Kim, C. Y., Lundin, K. E. & Sollid, L. M. T?Cell response to gluten in patients with HLA?DQ2. 2 reveals requirement of peptide-MHC stability in celiac disease. Gastroenterology 142, 552-561 (2012).
-
(2012)
Gastroenterology
, vol.142
, pp. 552-561
-
-
Bodd, M.1
Kim, C.Y.2
Lundin, K.E.3
Sollid, L.M.4
-
40
-
-
70349444985
-
Differences in the risk of celiac disease associated with HLA?DQ2. 5 or HLA?DQ2. 2 are related to sustained gluten antigen presentation
-
Fallang, L. E. et al. Differences in the risk of celiac disease associated with HLA?DQ2. 5 or HLA?DQ2. 2 are related to sustained gluten antigen presentation. Nat. Immunol. 10, 1096-1101 (2009).
-
(2009)
Nat. Immunol.
, vol.10
, pp. 1096-1101
-
-
Fallang, L.E.1
-
41
-
-
57049132880
-
The role of HLA?DQ8 ?57 polymorphism in the anti-gluten T?cell response in coeliac disease
-
Hovhannisyan, Z. et al. The role of HLA?DQ8 ?57 polymorphism in the anti-gluten T?cell response in coeliac disease. Nature 456, 534-538 (2008).
-
(2008)
Nature
, vol.456
, pp. 534-538
-
-
Hovhannisyan, Z.1
-
42
-
-
0023252262
-
HLA?DQ gene contributes to susceptibility and resistance to insulin-dependent diabetes-mellitus
-
Todd, J. A., Bell, J. I. & McDevitt, H. O. HLA?DQ gene contributes to susceptibility and resistance to insulin-dependent diabetes-mellitus. Nature 329, 599-604 (1987).
-
(1987)
Nature
, vol.329
, pp. 599-604
-
-
Todd, J.A.1
Bell, J.I.2
McDevitt, H.O.3
-
43
-
-
0034697101
-
A structural framework for deciphering the link between I-Ag7 and autoimmune diabetes
-
Corper, A. L. et al. A structural framework for deciphering the link between I-Ag7 and autoimmune diabetes. Science 288, 505-511 (2000).
-
(2000)
Science
, vol.288
, pp. 505-511
-
-
Corper, A.L.1
-
44
-
-
84867882809
-
Biased T cell receptor usage directed against human leukocyte antigen DQ8?restricted gliadin peptides is associated with celiac disease
-
Broughton, S. E. et al. Biased T cell receptor usage directed against human leukocyte antigen DQ8?restricted gliadin peptides is associated with celiac disease. Immunity 37, 611-621 (2012).
-
(2012)
Immunity
, vol.37
, pp. 611-621
-
-
Broughton, S.E.1
-
45
-
-
84902078635
-
T?Cell receptor recognition of HLA?DQ2?gliadin complexes associated with celiac disease
-
Petersen, J. et al. T?Cell receptor recognition of HLA?DQ2?gliadin complexes associated with celiac disease. Nat. Struct. Mol. Biol. 21, 480-488 (2014).
-
(2014)
Nat. Struct. Mol. Biol.
, vol.21
, pp. 480-488
-
-
Petersen, J.1
-
46
-
-
0030838044
-
Identification of tissue transglutaminase as the autoantigen of celiac disease
-
Dieterich, W. et al. Identification of tissue transglutaminase as the autoantigen of celiac disease. Nat. Med. 3, 797-801 (1997).
-
(1997)
Nat. Med.
, vol.3
, pp. 797-801
-
-
Dieterich, W.1
-
47
-
-
33845622856
-
Isotype distribution of anti-cyclic citrullinated peptide antibodies in undifferentiated arthritis and rheumatoid arthritis reflects an ongoing immune response
-
Verpoort, K. N. et al. Isotype distribution of anti-cyclic citrullinated peptide antibodies in undifferentiated arthritis and rheumatoid arthritis reflects an ongoing immune response. Arthritis Rheum. 54, 3799-3808 (2006).
-
(2006)
Arthritis Rheum.
, vol.54
, pp. 3799-3808
-
-
Verpoort, K.N.1
-
48
-
-
84992027493
-
A large fraction of HLA class i ligands are proteasome-generated spliced peptides
-
Liepe, J. et al. A large fraction of HLA class I ligands are proteasome-generated spliced peptides. Science 354, 354-358 (2016).
-
(2016)
Science
, vol.354
, pp. 354-358
-
-
Liepe, J.1
-
49
-
-
67649842408
-
MHC class i antigen presentation: Learning from viral evasion strategies
-
Hansen, T. H. & Bouvier, M. MHC class I antigen presentation: learning from viral evasion strategies. Nat. Rev. Immunol. 9, 503-513 (2009).
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 503-513
-
-
Hansen, T.H.1
Bouvier, M.2
-
50
-
-
84945976228
-
N?Terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes
-
Jin, N. et al. N?Terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes. Proc. Natl Acad. Sci. USA 112, 13318-13323 (2015).
-
(2015)
Proc. Natl Acad. Sci. USA
, vol.112
, pp. 13318-13323
-
-
Jin, N.1
-
51
-
-
84957922058
-
Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion
-
Delong, T. et al. Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion. Science 351, 711-714 (2016).
-
(2016)
Science
, vol.351
, pp. 711-714
-
-
Delong, T.1
-
52
-
-
84961275681
-
Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity
-
Raj, P. et al. Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity. eLife 5, e12089 (2016).
-
(2016)
ELife
, vol.5
, pp. e12089
-
-
Raj, P.1
-
53
-
-
80052701463
-
The molecular origin and consequences of escape from miRNA regulation by HLA?C alleles
-
O'Huigin, C. et al. The molecular origin and consequences of escape from miRNA regulation by HLA?C alleles. Am. J. Hum. Genet. 89, 424-431 (2011).
-
(2011)
Am. J. Hum. Genet.
, vol.89
, pp. 424-431
-
-
O'Huigin, C.1
-
54
-
-
84855912630
-
Bare lymphocyte syndrome: An opportunity to discover our immune system
-
Shrestha, D., Szollosi, J. & Jenei, A. Bare lymphocyte syndrome: an opportunity to discover our immune system. Immunol. Lett. 141, 147-157 (2012).
-
(2012)
Immunol. Lett.
, vol.141
, pp. 147-157
-
-
Shrestha, D.1
Szollosi, J.2
Jenei, A.3
-
55
-
-
33847615627
-
Host shutoff during productive Epstein-Barr virus infection is mediated by BGLF5 and may contribute to immune evasion
-
Rowe, M. et al. Host shutoff during productive Epstein-Barr virus infection is mediated by BGLF5 and may contribute to immune evasion. Proc. Natl Acad. Sci. USA 104, 3366-3371 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 3366-3371
-
-
Rowe, M.1
-
56
-
-
84960445097
-
Repression of CIITA by the Epstein-Barr virus transcription factor Zta is independent of its dimerization and DNA binding
-
Balan, N., Osborn, K. & Sinclair, A. J. Repression of CIITA by the Epstein-Barr virus transcription factor Zta is independent of its dimerization and DNA binding. J. Gen. Virol. 97, 725-732 (2016).
-
(2016)
J. Gen. Virol.
, vol.97
, pp. 725-732
-
-
Balan, N.1
Osborn, K.2
Sinclair, A.J.3
-
57
-
-
84919465848
-
HLA?C expression levels define permissible mismatches in hematopoietic cell transplantation
-
Petersdorf, E. W. et al. HLA?C expression levels define permissible mismatches in hematopoietic cell transplantation. Blood 124, 3996-4003 (2014).
-
(2014)
Blood
, vol.124
, pp. 3996-4003
-
-
Petersdorf, E.W.1
-
58
-
-
84941622235
-
High HLA?DP expression and graft-versus-host disease
-
Petersdorf, E. W. et al. High HLA?DP expression and graft-versus-host disease. N. Engl. J. Med. 373, 599-609 (2015).
-
(2015)
N. Engl. J. Med.
, vol.373
, pp. 599-609
-
-
Petersdorf, E.W.1
-
59
-
-
85014448693
-
HLA?G: At the interface of maternal-fetal tolerance
-
Ferreira, L. M. R., Meissner, T. B., Tilburgs, T. & Strominger, J. L. HLA?G: at the interface of maternal-fetal tolerance. Trends Immunol. 38, 272-286 (2017).
-
(2017)
Trends Immunol.
, vol.38
, pp. 272-286
-
-
Ferreira, L.M.R.1
Meissner, T.B.2
Tilburgs, T.3
Strominger, J.L.4
-
60
-
-
84927552890
-
A combination of single nucleotide polymorphisms in the 3' untranslated region of HLA?G is associated with preeclampsia
-
Quach, K., Grover, S. A., Kenigsberg, S. & Librach, C. L. A combination of single nucleotide polymorphisms in the 3' untranslated region of HLA?G is associated with preeclampsia. Hum. Immunol. 75, 1163-1170 (2014).
-
(2014)
Hum. Immunol.
, vol.75
, pp. 1163-1170
-
-
Quach, K.1
Grover, S.A.2
Kenigsberg, S.3
Librach, C.L.4
-
61
-
-
0025076114
-
Empty MHC class?I molecules come out in the cold
-
Ljunggren, H. G. et al. Empty MHC class?I molecules come out in the cold. Nature 346, 476-480 (1990).
-
(1990)
Nature
, vol.346
, pp. 476-480
-
-
Ljunggren, H.G.1
-
62
-
-
34547121970
-
Selective loading of high-affinity peptides onto major histocompatibility complex class i molecules by the tapasin?ERp57 heterodimer
-
Wearsch, P. A. & Cresswell, P. Selective loading of high-affinity peptides onto major histocompatibility complex class I molecules by the tapasin?ERp57 heterodimer. Nat. Immunol. 8, 873-881 (2007).
-
(2007)
Nat. Immunol.
, vol.8
, pp. 873-881
-
-
Wearsch, P.A.1
Cresswell, P.2
-
63
-
-
0036230677
-
Optimization of the MHC class i peptide cargo is dependent on tapasin
-
Williams, A. P., Peh, C. A., Purcell, A. W., McCluskey, J. & Elliott, T. Optimization of the MHC class I peptide cargo is dependent on tapasin. Immunity 16, 509-520 (2002).
-
(2002)
Immunity
, vol.16
, pp. 509-520
-
-
Williams, A.P.1
Peh, C.A.2
Purcell, A.W.3
McCluskey, J.4
Elliott, T.5
-
64
-
-
84969405928
-
Distinct assembly profiles of HLA?B molecules
-
Rizvi, S. M. et al. Distinct assembly profiles of HLA?B molecules. J. Immunol. 192, 4967-4976 (2014).
-
(2014)
J. Immunol.
, vol.192
, pp. 4967-4976
-
-
Rizvi, S.M.1
-
65
-
-
33747766822
-
HLA?B44 polymorphisms at position 116 of the heavy chain influence TAP complex minding via an effect on peptide occupancy
-
Thammavongsa, V., Raghuraman, G., Filzen, T. M., Collins, K. L. & Raghavan, M. HLA?B44 polymorphisms at position 116 of the heavy chain influence TAP complex minding via an effect on peptide occupancy. J. Immunol. 177, 3150-3161 (2006).
-
(2006)
J. Immunol.
, vol.177
, pp. 3150-3161
-
-
Thammavongsa, V.1
Raghuraman, G.2
Filzen, T.M.3
Collins, K.L.4
Raghavan, M.5
-
66
-
-
2942753075
-
Natural HLA class i polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion
-
Zernich, D. et al. Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion. J. Exp. Med. 200, 13-24 (2004).
-
(2004)
J. Exp. Med.
, vol.200
, pp. 13-24
-
-
Zernich, D.1
-
67
-
-
84927602620
-
Relative expression levels of the HLA class?I proteins in normal and HIV-infected cells
-
Apps, R. et al. Relative expression levels of the HLA class?I proteins in normal and HIV-infected cells. J. Immunol. 194, 3594-3600 (2015).
-
(2015)
J. Immunol.
, vol.194
, pp. 3594-3600
-
-
Apps, R.1
-
68
-
-
85021421984
-
Structural and regulatory diversity shape HLA?C protein expression levels
-
Kaur, G. et al. Structural and regulatory diversity shape HLA?C protein expression levels. Nat. Commun. 8, 15924 (2017).
-
(2017)
Nat. Commun.
, vol.8
, pp. 15924
-
-
Kaur, G.1
-
69
-
-
85058216329
-
Class i HLA haplotypes form two schools that educate NK cells in different ways
-
Horowitz, A. et al. Class I HLA haplotypes form two schools that educate NK cells in different ways. Sci. Immunol. 1, eaag1672 (2016).
-
(2016)
Sci. Immunol.
, vol.1
, pp. eaag1672
-
-
Horowitz, A.1
-
70
-
-
84874606648
-
Genome-wide association study of spontaneous resolution of hepatitis C virus infection: Data from multiple cohorts
-
Duggal, P. et al. Genome-wide association study of spontaneous resolution of hepatitis C virus infection: data from multiple cohorts. Ann. Intern. Med. 158, 235-245 (2013).
-
(2013)
Ann. Intern. Med.
, vol.158
, pp. 235-245
-
-
Duggal, P.1
-
71
-
-
84920381515
-
Cell-surface MHC density profiling reveals instability of autoimmunity-associated HLA
-
Miyadera, H., Ohashi, J., Lernmark, Å., Kitamura, T. & Tokunaga, K. Cell-surface MHC density profiling reveals instability of autoimmunity-associated HLA. J. Clin. Invest. 125, 275-291 (2015).
-
(2015)
J. Clin. Invest.
, vol.125
, pp. 275-291
-
-
Miyadera, H.1
Ohashi, J.2
Lernmark, Å.3
Kitamura, T.4
Tokunaga, K.5
-
72
-
-
84883735387
-
Structural characteristics of HLA?DQ that may impact DM editing and susceptibility to type?1 diabetes
-
Zhou, Z. & Jensen, P. E. Structural characteristics of HLA?DQ that may impact DM editing and susceptibility to type?1 diabetes. Front. Immunol. 4, 262 (2013).
-
(2013)
Front. Immunol.
, vol.4
, pp. 262
-
-
Zhou, Z.1
Jensen, P.E.2
-
73
-
-
84857496758
-
High-density SNP mapping of the HLA region identifies multiple independent susceptibility loci associated with selective IgA deficiency
-
Ferreira, R. C. et al. High-density SNP mapping of the HLA region identifies multiple independent susceptibility loci associated with selective IgA deficiency. PLOS Genet. 8, e1002476 (2012).
-
(2012)
PLOS Genet.
, vol.8
, pp. e1002476
-
-
Ferreira, R.C.1
-
74
-
-
79952398727
-
Autoimmune polyglandular syndrome type 2 shows the same HLA class II pattern as type 1 diabetes
-
Weinstock, C. et al. Autoimmune polyglandular syndrome type 2 shows the same HLA class II pattern as type 1 diabetes. Tissue Antigens 77, 317-324 (2011).
-
(2011)
Tissue Antigens
, vol.77
, pp. 317-324
-
-
Weinstock, C.1
-
75
-
-
84938256620
-
Additive and interaction effects at three amino acid positions in HLA?DQ and HLA?DR molecules drive type 1 diabetes risk
-
Hu, X. L. et al. Additive and interaction effects at three amino acid positions in HLA?DQ and HLA?DR molecules drive type 1 diabetes risk. Nat. Genet. 47, 898-905 (2015).
-
(2015)
Nat. Genet.
, vol.47
, pp. 898-905
-
-
Hu, X.L.1
-
76
-
-
0035091595
-
Complex HLA?DR and-DQ interactions confer risk of narcolepsy-cataplexy in three ethnic groups
-
Mignot, E. et al. Complex HLA?DR and-DQ interactions confer risk of narcolepsy-cataplexy in three ethnic groups. Am. J. Hum. Genet. 68, 686-699 (2001).
-
(2001)
Am. J. Hum. Genet.
, vol.68
, pp. 686-699
-
-
Mignot, E.1
-
77
-
-
85028691452
-
Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank
-
Cortes, A. et al. Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank. Nat. Genet. 49, 1311-1318 (2017).
-
(2017)
Nat. Genet.
, vol.49
, pp. 1311-1318
-
-
Cortes, A.1
-
78
-
-
84948712615
-
MHC-I-opathy-unified concept for spondyloarthritis and Behcet disease
-
McGonagle, D., Aydin, S. Z., Gul, A., Mahr, A. & Direskeneli, H. MHC-I-opathy-unified concept for spondyloarthritis and Behcet disease. Nat. Rev. Rheumatol. 11, 731-740 (2015).
-
(2015)
Nat. Rev. Rheumatol.
, vol.11
, pp. 731-740
-
-
McGonagle, D.1
Aydin, S.Z.2
Gul, A.3
Mahr, A.4
Direskeneli, H.5
-
79
-
-
84956807918
-
Genetics of ankylosing spondylitis-insights into pathogenesis
-
Brown, M. A., Kenna, T. & Wordsworth, B. P. Genetics of ankylosing spondylitis-insights into pathogenesis. Nat. Rev. Rheumatol. 12, 81-91 (2016).
-
(2016)
Nat. Rev. Rheumatol.
, vol.12
, pp. 81-91
-
-
Brown, M.A.1
Kenna, T.2
Wordsworth, B.P.3
-
80
-
-
84940590102
-
Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases
-
Lenz, T. L. et al. Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases. Nat. Genet. 47, 1085-1090 (2015).
-
(2015)
Nat. Genet.
, vol.47
, pp. 1085-1090
-
-
Lenz, T.L.1
-
81
-
-
0142091358
-
The HLA?DQ2 gene dose effect in celiac disease is directly related to the magnitude and breadth of gluten-specific T cell responses
-
Vader, W. et al. The HLA?DQ2 gene dose effect in celiac disease is directly related to the magnitude and breadth of gluten-specific T cell responses. Proc. Natl Acad. Sci. USA 100, 12390-12395 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 12390-12395
-
-
Vader, W.1
-
82
-
-
33749515298
-
Functional epistasis on a common MHC haplotype associated with multiple sclerosis
-
Gregersen, J. W. et al. Functional epistasis on a common MHC haplotype associated with multiple sclerosis. Nature 443, 574-577 (2006).
-
(2006)
Nature
, vol.443
, pp. 574-577
-
-
Gregersen, J.W.1
-
83
-
-
85021661653
-
T cells from patients with Parkinson's disease recognize ?-synuclein peptides
-
Sulzer, D. et al. T cells from patients with Parkinson's disease recognize ?-synuclein peptides. Nature 546, 656-661 (2017).
-
(2017)
Nature
, vol.546
, pp. 656-661
-
-
Sulzer, D.1
-
84
-
-
55549116694
-
Host ethnicity and virus genotype shape the hepatitis B virus-specific T?cell repertoire
-
Tan, A. T. et al. Host ethnicity and virus genotype shape the hepatitis B virus-specific T?cell repertoire. J. Virol. 82, 10986-10997 (2008).
-
(2008)
J. Virol.
, vol.82
, pp. 10986-10997
-
-
Tan, A.T.1
-
85
-
-
85017255964
-
Genome-to?genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus
-
Ansari, M. A. et al. Genome-to?genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus. Nat. Genet, 49, 666-673 (2017).
-
(2017)
Nat. Genet
, vol.49
, pp. 666-673
-
-
Ansari, M.A.1
-
86
-
-
84908876253
-
A human vaccine strategy based on chimpanzee adenoviral and MVA vectors that primes, boosts, and sustains functional HCV-specific T cell memory
-
Swadling, L. et al. A human vaccine strategy based on chimpanzee adenoviral and MVA vectors that primes, boosts, and sustains functional HCV-specific T cell memory. Sci. Transl. Med. 6, 261ra153 (2014).
-
(2014)
Sci. Transl. Med.
, vol.6
, pp. 261ra153
-
-
Swadling, L.1
-
87
-
-
84889885286
-
Subinfectious hepatitis C virus exposures suppress T cell responses against subsequent acute infection
-
Park, S. H. et al. Subinfectious hepatitis C virus exposures suppress T cell responses against subsequent acute infection. Nat. Med. 19, 1638-1642 (2013).
-
(2013)
Nat. Med.
, vol.19
, pp. 1638-1642
-
-
Park, S.H.1
-
88
-
-
84946565788
-
Comprehensive analysis of cancer-associated somatic mutations in class i HLA genes
-
Shukla, S. A. et al. Comprehensive analysis of cancer-associated somatic mutations in class I HLA genes. Nat. Biotechnol. 33, 1152-1158 (2015).
-
(2015)
Nat. Biotechnol.
, vol.33
, pp. 1152-1158
-
-
Shukla, S.A.1
-
89
-
-
85032583704
-
Allele-specific HLA loss and immune escape in lung cancer evolution
-
McGranahan, N. et al. Allele-specific HLA loss and immune escape in lung cancer evolution. Cell 171, 1259-1271. e11 (2017).
-
(2017)
Cell
, vol.171
, pp. 1259e11-1271e11
-
-
McGranahan, N.1
-
90
-
-
85032580176
-
MHC?1 genotype restricts the oncogenic mutational landscape
-
Marty, R. et al. MHC?1 genotype restricts the oncogenic mutational landscape. Cell 171, 1272-1283. e15 (2017).
-
(2017)
Cell
, vol.171
, pp. 1272e15-1283e15
-
-
Marty, R.1
-
91
-
-
0036481263
-
Epitope spreading in immune-mediated diseases: Implications for immunotherapy
-
Vanderlugt, C. L. & Miller, S. D. Epitope spreading in immune-mediated diseases: implications for immunotherapy. Nat. Rev. Immunol. 2, 85-95 (2002).
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 85-95
-
-
Vanderlugt, C.L.1
Miller, S.D.2
-
92
-
-
0036082955
-
The gluten response in children with celiac disease is directed toward multiple gliadin and glutenin peptides
-
Vader, W. et al. The gluten response in children with celiac disease is directed toward multiple gliadin and glutenin peptides. Gastroenterology 122, 1729-1737 (2002).
-
(2002)
Gastroenterology
, vol.122
, pp. 1729-1737
-
-
Vader, W.1
-
93
-
-
0029743737
-
Phenotypic analysis of antigen-specific T lymphocytes
-
Altman, J. D. et al. Phenotypic analysis of antigen-specific T lymphocytes. Science 274, 94-96 (1996).
-
(1996)
Science
, vol.274
, pp. 94-96
-
-
Altman, J.D.1
-
94
-
-
84904240682
-
Comparison of peptide-major histocompatibility complex tetramers and dextramers for the identification of antigen-specific T cells
-
Dolton, G. et al. Comparison of peptide-major histocompatibility complex tetramers and dextramers for the identification of antigen-specific T cells. Clin. Exp. Immunol. 177, 47-63 (2014).
-
(2014)
Clin. Exp. Immunol.
, vol.177
, pp. 47-63
-
-
Dolton, G.1
-
95
-
-
84857822895
-
MHC class II tetramers
-
Nepom, G. T. MHC class II tetramers. J. Immunol. 188, 2477-2482 (2012).
-
(2012)
J. Immunol.
, vol.188
, pp. 2477-2482
-
-
Nepom, G.T.1
-
96
-
-
84880289310
-
Combinatorial tetramer staining and mass cytometry analysis facilitate T?cell epitope mapping and characterization
-
Newell, E. W. et al. Combinatorial tetramer staining and mass cytometry analysis facilitate T?cell epitope mapping and characterization. Nat. Biotechnol. 31, 623-629 (2013).
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 623-629
-
-
Newell, E.W.1
-
97
-
-
85022229481
-
Identifying specificity groups in the T cell receptor repertoire
-
Glanville, J. et al. Identifying specificity groups in the T cell receptor repertoire. Nature 547, 94-98 (2017).
-
(2017)
Nature
, vol.547
, pp. 94-98
-
-
Glanville, J.1
-
98
-
-
84960194523
-
T cell fate and clonality inference from single-cell transcriptomes
-
Stubbington, M. J. et al. T cell fate and clonality inference from single-cell transcriptomes. Nat. Methods 13, 329-332 (2016).
-
(2016)
Nat. Methods
, vol.13
, pp. 329-332
-
-
Stubbington, M.J.1
-
99
-
-
84976292366
-
Hydrophobic CDR3 residues promote the development of self-reactive T cells
-
Stadinski, B. D. et al. Hydrophobic CDR3 residues promote the development of self-reactive T cells. Nat. Immunol. 17, 946-955 (2016).
-
(2016)
Nat. Immunol.
, vol.17
, pp. 946-955
-
-
Stadinski, B.D.1
-
100
-
-
84901295133
-
Deconstructing the peptide-MHC specificity of T cell recognition
-
Birnbaum, M. E. et al. Deconstructing the peptide-MHC specificity of T cell recognition. Cell 157, 1073-1087 (2014).
-
(2014)
Cell
, vol.157
, pp. 1073-1087
-
-
Birnbaum, M.E.1
-
101
-
-
80052677601
-
TCRs used in cancer gene therapy cross-react with MART?1/Melan?A tumor antigens via distinct mechanisms
-
Borbulevych, O. Y., Santhanagopolan, S. M., Hossain, M. & Baker, B. M. TCRs used in cancer gene therapy cross-react with MART?1/Melan?A tumor antigens via distinct mechanisms. J. Immunol. 187, 2453-2463 (2011).
-
(2011)
J. Immunol.
, vol.187
, pp. 2453-2463
-
-
Borbulevych, O.Y.1
Santhanagopolan, S.M.2
Hossain, M.3
Baker, B.M.4
-
102
-
-
84877957880
-
Cytomegalovirus vectors violate CD8+ T cell epitope recognition paradigms
-
Hansen, S. G. et al. Cytomegalovirus vectors violate CD8+ T cell epitope recognition paradigms. Science 340, 1237874 (2013).
-
(2013)
Science
, vol.340
, pp. 1237874
-
-
Hansen, S.G.1
-
103
-
-
84944879331
-
T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex
-
Beringer, D. X. et al. T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex. Nat. Immunol. 16, 1153-1161 (2015).
-
(2015)
Nat. Immunol.
, vol.16
, pp. 1153-1161
-
-
Beringer, D.X.1
-
104
-
-
84994885777
-
Reversed T cell receptor docking on a major histocompatibility class i complex limits involvement in the immune response
-
Gras, S. et al. Reversed T cell receptor docking on a major histocompatibility class I complex limits involvement in the immune response. Immunity 45, 749-760 (2016).
-
(2016)
Immunity
, vol.45
, pp. 749-760
-
-
Gras, S.1
-
105
-
-
84937422078
-
Efficacy and safety of RTS, S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: Final results of a phase 3, individually randomised, controlled trial
-
RTS, S Clinical Trials Partnership
-
RTS, S Clinical Trials Partnership. Efficacy and safety of RTS, S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial. Lancet 386, 31-45 (2015).
-
(2015)
Lancet
, vol.386
, pp. 31-45
-
-
-
106
-
-
84940952795
-
Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: Interim results from the Guinea ring vaccination cluster-randomised trial
-
Henao-Restrepo, A. M. et al. Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial. Lancet 386, 857-866 (2015).
-
(2015)
Lancet
, vol.386
, pp. 857-866
-
-
Henao-Restrepo, A.M.1
-
107
-
-
84942436806
-
Efficacy and long-term safety of a Dengue vaccine in regions of endemic disease
-
Hadinegoro, S. R. et al. Efficacy and long-term safety of a Dengue vaccine in regions of endemic disease. N. Engl. J. Med. 373, 1195-1206 (2015).
-
(2015)
N. Engl. J. Med.
, vol.373
, pp. 1195-1206
-
-
Hadinegoro, S.R.1
-
108
-
-
84895732582
-
The pertussis problem
-
Plotkin, S. A. The pertussis problem. Clin. Infect. Dis. 58, 830-833 (2014).
-
(2014)
Clin. Infect. Dis.
, vol.58
, pp. 830-833
-
-
Plotkin, S.A.1
-
109
-
-
33646490633
-
Human leukocyte antigen polymorphisms: Variable humoral immune responses to viral vaccines
-
Ovsyannikova, I. G., Dhiman, N., Jacobson, R. M. & Poland, G. A. Human leukocyte antigen polymorphisms: variable humoral immune responses to viral vaccines. Expert Rev. Vaccines 5, 33-43 (2006).
-
(2006)
Expert Rev. Vaccines
, vol.5
, pp. 33-43
-
-
Ovsyannikova, I.G.1
Dhiman, N.2
Jacobson, R.M.3
Poland, G.A.4
-
110
-
-
85015916804
-
The immunogenetics of narcolepsy associated with A(H1N1)pdm09 vaccination (Pandemrix) supports a potent gene-environment interaction
-
Bomfim, I. L. et al. The immunogenetics of narcolepsy associated with A(H1N1)pdm09 vaccination (Pandemrix) supports a potent gene-environment interaction. Genes Immun. 18, 75-81 (2017).
-
(2017)
Genes Immun.
, vol.18
, pp. 75-81
-
-
Bomfim, I.L.1
-
111
-
-
85016410136
-
Effect of simultaneous vaccination with H1N1 and GAD-alum on GAD65?induced immune response
-
Tavira, B. et al. Effect of simultaneous vaccination with H1N1 and GAD-alum on GAD65?induced immune response. Diabetologia 60, 1276-1283 (2017).
-
(2017)
Diabetologia
, vol.60
, pp. 1276-1283
-
-
Tavira, B.1
-
112
-
-
17644401678
-
Peptide-based therapeutic vaccines for allergic and autoimmune diseases
-
Larche, M. & Wraith, D. C. Peptide-based therapeutic vaccines for allergic and autoimmune diseases. Nat. Med. 11, S69-S76 (2005).
-
(2005)
Nat. Med.
, vol.11
, pp. S69-S76
-
-
Larche, M.1
Wraith, D.C.2
-
113
-
-
85027408203
-
Metabolic and immune effects of immunotherapy with proinsulin peptide in human new-onset type 1 diabetes
-
Alhadj Ali, M. et al. Metabolic and immune effects of immunotherapy with proinsulin peptide in human new-onset type 1 diabetes. Sci. Transl. Med. 9, eaaf7779 (2017).
-
(2017)
Sci. Transl. Med.
, vol.9
, pp. eaaf7779
-
-
Alhadj Ali, M.1
-
114
-
-
84975527586
-
Mechanistic understanding and significance of small peptides interaction with MHC class II molecules for therapeutic applications
-
Afridi, S., Hoessli, D. C. & Hameed, M. W. Mechanistic understanding and significance of small peptides interaction with MHC class II molecules for therapeutic applications. Immunol. Rev. 272, 151-168 (2016).
-
(2016)
Immunol. Rev.
, vol.272
, pp. 151-168
-
-
Afridi, S.1
Hoessli, D.C.2
Hameed, M.W.3
-
115
-
-
85013482359
-
Intralymphatic injection of autoantigen in type 1 diabetes
-
Ludvigsson, J., Wahlberg, J. & Casas, R. Intralymphatic injection of autoantigen in type 1 diabetes. N. Engl. J. Med. 376, 697-699 (2017).
-
(2017)
N. Engl. J. Med.
, vol.376
, pp. 697-699
-
-
Ludvigsson, J.1
Wahlberg, J.2
Casas, R.3
-
116
-
-
84959450362
-
Expanding antigen-specific regulatory networks to treat autoimmunity
-
Clemente-Casares, X. et al. Expanding antigen-specific regulatory networks to treat autoimmunity. Nature 530, 434-440 (2016).
-
(2016)
Nature
, vol.530
, pp. 434-440
-
-
Clemente-Casares, X.1
-
117
-
-
84964597343
-
Dendritic cell-derived exosomes for cancer therapy
-
Pitt, J. M. et al. Dendritic cell-derived exosomes for cancer therapy. J. Clin. Invest. 126, 1224-1232 (2016).
-
(2016)
J. Clin. Invest.
, vol.126
, pp. 1224-1232
-
-
Pitt, J.M.1
-
118
-
-
84862025335
-
Monoclonal TCR-redirected tumor cell killing
-
Liddy, N. et al. Monoclonal TCR-redirected tumor cell killing. Nat. Med. 18, 980-987 (2012).
-
(2012)
Nat. Med.
, vol.18
, pp. 980-987
-
-
Liddy, N.1
-
119
-
-
84954443667
-
Type 1 diabetes immunotherapy using polyclonal regulatory T cells
-
Bluestone, J. A. et al. Type 1 diabetes immunotherapy using polyclonal regulatory T cells. Sci. Transl. Med. 7, 315ra189 (2015).
-
(2015)
Sci. Transl. Med.
, vol.7
, pp. 315ra189
-
-
Bluestone, J.A.1
-
120
-
-
85032276992
-
Polyclonal regulatory T cell therapy for control of inflammation in kidney transplants
-
Chandran, S. et al. Polyclonal regulatory T cell therapy for control of inflammation in kidney transplants. Am. J. Transplant. 17, 2945-2954 (2017).
-
(2017)
Am. J. Transplant.
, vol.17
, pp. 2945-2954
-
-
Chandran, S.1
-
121
-
-
84976406873
-
Neoantigen landscape dynamics during human melanoma?T cell interactions
-
Verdegaal, E. M. E. et al. Neoantigen landscape dynamics during human melanoma?T cell interactions. Nature 536, 91-95 (2016).
-
(2016)
Nature
, vol.536
, pp. 91-95
-
-
Verdegaal, E.M.E.1
-
122
-
-
84969764539
-
Targeting of cancer neoantigens with donor-derived T cell receptor repertoires
-
Stronen, E. et al. Targeting of cancer neoantigens with donor-derived T cell receptor repertoires. Science 352, 1337-1341 (2016).
-
(2016)
Science
, vol.352
, pp. 1337-1341
-
-
Stronen, E.1
-
123
-
-
33749137515
-
A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC
-
de Bakker, P. I. W. et al. A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC. Nat. Genet. 38, 1166-1172 (2006).
-
(2006)
Nat. Genet.
, vol.38
, pp. 1166-1172
-
-
De Bakker, P.I.W.1
-
124
-
-
84930083227
-
Improved genome inference in the MHC using a population reference graph
-
Dilthey, A., Cox, C., Iqbal, Z., Nelson, M. R. & McVean, G. Improved genome inference in the MHC using a population reference graph. Nat. Genet. 47, 682-688 (2015).
-
(2015)
Nat. Genet.
, vol.47
, pp. 682-688
-
-
Dilthey, A.1
Cox, C.2
Iqbal, Z.3
Nelson, M.R.4
McVean, G.5
-
125
-
-
84862776511
-
Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis
-
Raychaudhuri, S. et al. Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis. Nat. Genet. 44, 291-296 (2012).
-
(2012)
Nat. Genet.
, vol.44
, pp. 291-296
-
-
Raychaudhuri, S.1
-
126
-
-
84969786267
-
Deep sequencing of the MHC region in the Chinese population contributes to studies of complex disease
-
Zhou, F. S. et al. Deep sequencing of the MHC region in the Chinese population contributes to studies of complex disease. Nat. Genet. 48, 740-746 (2016).
-
(2016)
Nat. Genet.
, vol.48
, pp. 740-746
-
-
Zhou, F.S.1
-
127
-
-
84938363499
-
More tricks with tetramers: A practical guide to staining T cells with peptide-MHC multimers
-
Dolton, G. et al. More tricks with tetramers: a practical guide to staining T cells with peptide-MHC multimers. Immunology 146, 11-22 (2015).
-
(2015)
Immunology
, vol.146
, pp. 11-22
-
-
Dolton, G.1
-
128
-
-
78651490414
-
High prevalence of low affinity peptide-MHC II tetramer-negative effectors during polyclonal CD4+ T cell responses
-
Sabatino, J. J. Jr, Huang, J., Zhu, C. & Evavold, B. D. High prevalence of low affinity peptide-MHC II tetramer-negative effectors during polyclonal CD4+ T cell responses. J. Exp. Med. 208, 81-90 (2011).
-
(2011)
J. Exp. Med.
, vol.208
, pp. 81-90
-
-
Sabatino, J.J.1
Huang, J.2
Zhu, C.3
Evavold, B.D.4
-
129
-
-
84855555044
-
Autoimmunity's next top models
-
Wekerle, H., Flugel, A., Fugger, L., Schett, G. & Serreze, D. Autoimmunity's next top models. Nat. Med. 18, 66-70 (2012).
-
(2012)
Nat. Med.
, vol.18
, pp. 66-70
-
-
Wekerle, H.1
Flugel, A.2
Fugger, L.3
Schett, G.4
Serreze, D.5
-
130
-
-
36048946330
-
Roquin represses autoimmunity by limiting inducible T?cell co?stimulator messenger RNA
-
Yu, D. et al. Roquin represses autoimmunity by limiting inducible T?cell co?stimulator messenger RNA. Nature 450, 299-303 (2007).
-
(2007)
Nature
, vol.450
, pp. 299-303
-
-
Yu, D.1
|