메뉴 건너뛰기




Volumn 16, Issue 11, 2015, Pages 1114-1123

The burgeoning family of unconventional T cells

Author keywords

[No Author keywords available]

Indexed keywords

CD1 ANTIGEN; CD1D ANTIGEN; HLA ANTIGEN CLASS 1; LYMPHOCYTE ANTIGEN RECEPTOR;

EID: 84944881339     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3298     Document Type: Review
Times cited : (611)

References (159)
  • 1
    • 0025836948 scopus 로고
    • Site-specific recombination in the immune system
    • Lieber M.R. Site-specific recombination in the immune system. FASEB J. 5, 2934-2944 (1991
    • (1991) Faseb J. , vol.5 , pp. 2934-2944
    • Lieber, M.R.1
  • 2
    • 0033615678 scopus 로고    scopus 로고
    • A direct estimate of the human alphabeta T cell receptor diversity
    • Arstila T.P., et al. A direct estimate of the human alphabeta T cell receptor diversity. Science 286, 958-961 (1999
    • (1999) Science , vol.286 , pp. 958-961
    • Arstila, T.P.1
  • 3
    • 84860346184 scopus 로고    scopus 로고
    • The role of naive T cell precursor frequency and recruitment in dictating immune response magnitude
    • Jenkins M.K., & Moon J.J. The role of naive T cell precursor frequency and recruitment in dictating immune response magnitude. J. Immunol. 188, 4135-4140 (2012
    • (2012) J. Immunol , vol.188 , pp. 4135-4140
    • Jenkins, M.K.1    Moon, J.J.2
  • 5
  • 10
    • 84865399909 scopus 로고    scopus 로고
    • Immunomodulatory type II natural killer T lymphocytes in health and disease
    • Rhost S., Sedimbi S., Kadri N., & Cardell S.L. Immunomodulatory type II natural killer T lymphocytes in health and disease. Scand. J. Immunol. 76, 246-255 (2012
    • (2012) Scand. J. Immunol , vol.76 , pp. 246-255
    • Rhost, S.1    Sedimbi, S.2    Kadri, N.3    Cardell, S.L.4
  • 11
    • 0030696696 scopus 로고    scopus 로고
    • Cd1d-restricted and TCR-mediated Activation of V14 NKT cells by glycosylceramides
    • Kawano T., et al. Cd1d-restricted and TCR-mediated Activation of V14 NKT cells by glycosylceramides. Science 278, 1626-1629 (1997
    • (1997) Science , vol.278 , pp. 1626-1629
    • Kawano, T.1
  • 12
  • 13
    • 84892171393 scopus 로고    scopus 로고
    • NKT cells as an ideal anti-tumor immunotherapeutic
    • Fujii S.I., et al. NKT cells as an ideal anti-tumor immunotherapeutic. Front. Immunology 4, 409 (2013
    • (2013) Front. Immunology , vol.4 , pp. 409
    • Fujii, S.I.1
  • 14
    • 0035423370 scopus 로고    scopus 로고
    • CD1d-restricted NKT cells: An interstrain comparison
    • Hammond K.J.L., et al. CD1d-restricted NKT cells: An interstrain comparison. J. Immunol. 167, 1164-1173 (2001
    • (2001) J. Immunol , vol.167 , pp. 1164-1173
    • Hammond, K.J.L.1
  • 15
    • 84874994399 scopus 로고    scopus 로고
    • Ex-vivo analysis of human natural killer T cells demonstrates het-erogeneity between tissues and within established CD4+ and CD4- subsets
    • Chan A.C., et al. Ex-vivo analysis of human natural killer T cells demonstrates het-erogeneity between tissues and within established CD4+ and CD4- subsets. Clin. Exp. Immunol. 172, 129-137 (2013
    • (2013) Clin. Exp. Immunol , vol.172 , pp. 129-137
    • Chan, A.C.1
  • 16
    • 84860238236 scopus 로고    scopus 로고
    • Interplay between carbohydrate and lipid in recognition of glycolipid antigens by natural killer T cells
    • Pei B., Vela J.L., Zajonc D., & Kronenberg M. Interplay between carbohydrate and lipid in recognition of glycolipid antigens by natural killer T cells. Ann. NY Acad. Sci. 1253, 68-79 (2012
    • (2012) Ann. NY Acad. Sci , vol.1253 , pp. 68-79
    • Pei, B.1    Vela, J.L.2    Zajonc, D.3    Kronenberg, M.4
  • 17
    • 34247613348 scopus 로고    scopus 로고
    • Implications for invariant natural killer T cell ligands due to the restricted presence of isoglobotrihexosylceramide in mammals
    • Speak A.O., et al. Implications for invariant natural killer T cell ligands due to the restricted presence of isoglobotrihexosylceramide in mammals. Proc. Natl. Acad. Sci. USA 104, 5971-5976 (2007
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 5971-5976
    • Speak, A.O.1
  • 18
    • 10044280324 scopus 로고    scopus 로고
    • Lysosomal glycosphingolipid recognition by NKT cells
    • Zhou D., et al. Lysosomal glycosphingolipid recognition by NKT cells. Science 306, 1786-1789 (2004
    • (2004) Science , vol.306 , pp. 1786-1789
    • Zhou, D.1
  • 19
    • 84907289353 scopus 로고    scopus 로고
    • Activation of iNKT cells by a distinct constituent of the endog-enous glucosylceramide fraction
    • Brennan P.J., et al. Activation of iNKT cells by a distinct constituent of the endog-enous glucosylceramide fraction. Proc. Natl. Acad. Sci. USA 111, 13433-13438 (2014
    • (2014) Proc. Natl. Acad. Sci. USA , vol.111 , pp. 13433-13438
    • Brennan, P.J.1
  • 20
    • 84908148732 scopus 로고    scopus 로고
    • The identification of the endogenous ligands of natural killer T cells reveals the presence of mammalian alpha-linked glycosylceramides
    • Kain L., et al. The identification of the endogenous ligands of natural killer T cells reveals the presence of mammalian alpha-linked glycosylceramides. Immunity 41, 543-554 (2014
    • (2014) Immunity , vol.41 , pp. 543-554
    • Kain, L.1
  • 21
    • 84957426921 scopus 로고    scopus 로고
    • Endogenous ligands of natural killer T cells are a-linked glycosylce-ramides
    • 30 June
    • Kain L., et al. Endogenous ligands of natural killer T cells are a-linked glycosylce-ramides. Mol. Immunol. doi: 10.1016/j.molimm.2015.06.009 (30 June2015
    • (2015) Mol. Immunol
    • Kain, L.1
  • 22
    • 84880941717 scopus 로고    scopus 로고
    • Production of a-galactosylceramide by a prominent mem-ber of the human gut microbiota
    • Wieland Brown L.C., et al. Production of a-galactosylceramide by a prominent mem-ber of the human gut microbiota. PLoS Biol. 11, e1001610 (2013
    • (2013) Plos Biol , vol.11 , pp. e1001610
    • Wieland Brown, L.C.1
  • 23
    • 0141958207 scopus 로고    scopus 로고
    • Glycolipid antigen drives rapid expansion and sustained cytokine production by NK T cells
    • Crowe N.Y., et al. Glycolipid antigen drives rapid expansion and sustained cytokine production by NK T cells. J. Immunol. 171, 4020-4027 (2003
    • (2003) J. Immunol , vol.171 , pp. 4020-4027
    • Crowe, N.Y.1
  • 24
    • 0141814650 scopus 로고    scopus 로고
    • The response of natural killer T cells to glycolipid antigens is characterized by surface receptor down-modulation and expansion
    • Wilson M.T., et al. The response of natural killer T cells to glycolipid antigens is characterized by surface receptor down-modulation and expansion. Proc. Natl. Acad. Sci. USA 100, 10913-10918 (2003
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 10913-10918
    • Wilson, M.T.1
  • 25
    • 49649123906 scopus 로고    scopus 로고
    • Diverse cytokine production by nkt cell subsets and identification of an il-17-producing cd4-nk1.1- nkt cell population
    • Coquet J.M., et al. Diverse cytokine production by NKT cell subsets and identification of an IL-17-producing CD4-NK1.1- NKT cell population. Proc. Natl. Acad. Sci. USA 105, 11287-11292 (2008
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 11287-11292
    • Coquet, J.M.1
  • 26
    • 78049384898 scopus 로고    scopus 로고
    • Antigen-specific cytotoxic-ity by invariant nkt cells in vivo is cd95/cd178-dependent and is correlated with antigenic potency
    • Wingender G., Krebs P., Beutler B., & Kronenberg M. Antigen-specific cytotoxic-ity by invariant NKT cells in vivo is CD95/CD178-dependent and is correlated with antigenic potency. J. Immunol. 185, 2721-2729 (2010
    • (2010) J. Immunol , vol.185 , pp. 2721-2729
    • Wingender, G.1    Krebs, P.2    Beutler, B.3    Kronenberg, M.4
  • 27
    • 0036882074 scopus 로고    scopus 로고
    • CD1-dependent dendritic cell instruction
    • Vincent M.S., et al. CD1-dependent dendritic cell instruction. Nat. Immunol. 3, 1163-1168 (2002
    • (2002) Nat. Immunol , vol.3 , pp. 1163-1168
    • Vincent, M.S.1
  • 28
    • 3042545974 scopus 로고    scopus 로고
    • The linkage of innate to adaptive immunity via maturing dendritic cells in vivo requires cd40 ligation in addition to antigen presentation and cd80/86 costimulation
    • Fujii S., Liu K., Smith C., Bonito A.J., & Steinman R.M. The linkage of innate to adaptive immunity via maturing dendritic cells in vivo requires CD40 ligation in addition to antigen presentation and CD80/86 costimulation. J. Exp. Med. 199, 1607-1618 (2004
    • (2004) J. Exp. Med , vol.199 , pp. 1607-1618
    • Fujii, S.1    Liu, K.2    Smith, C.3    Bonito, A.J.4    Steinman, R.M.5
  • 29
    • 0034002676 scopus 로고    scopus 로고
    • Selective induction of nk cell proliferation and cyto-toxicity by activated nkt cells
    • Eberl G., & MacDonald H.R. Selective induction of NK cell proliferation and cyto-toxicity by activated NKT cells. Eur. J. Immunol. 30, 985-992 (2000
    • (2000) Eur. J. Immunol , vol.30 , pp. 985-992
    • Eberl, G.1    MacDonald, H.R.2
  • 30
    • 0037460057 scopus 로고    scopus 로고
    • CD1d-restricted help to B cells by human invariant natural killer T lymphocytes
    • Galli G., et al. CD1d-restricted help to B cells by human invariant natural killer T lymphocytes. J. Exp. Med. 197, 1051-1057 (2003
    • (2003) J. Exp. Med , vol.197 , pp. 1051-1057
    • Galli, G.1
  • 32
    • 79955980763 scopus 로고    scopus 로고
    • Natural killer T cells in health and disease
    • Wu L., & Van Kaer L. Natural killer T cells in health and disease. Front. Biosci. 3, 236-251 (2011
    • (2011) Front. Biosci , vol.3 , pp. 236-251
    • Wu, L.1    Van Kaer, L.2
  • 33
    • 57449088879 scopus 로고    scopus 로고
    • Invariant NKT cells reduce the immunosuppressive activity of influenza A virus-induced myeloid-derived suppressor cells in mice and humans
    • De Santo C., et al. Invariant NKT cells reduce the immunosuppressive activity of influenza A virus-induced myeloid-derived suppressor cells in mice and humans. J. Clin. Invest. 118, 4036-4048 (2008
    • (2008) J. Clin. Invest , vol.118 , pp. 4036-4048
    • De Santo, C.1
  • 34
    • 62549116236 scopus 로고    scopus 로고
    • Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity
    • Guillonneau C., et al. Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity. Proc. Natl. Acad. Sci. USA 106, 3330-3335 (2009
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 3330-3335
    • Guillonneau, C.1
  • 35
    • 83755166410 scopus 로고    scopus 로고
    • Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses
    • Chang P.P., et al. Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses. Nat. Immunol. 13, 35-43 (2011
    • (2011) Nat. Immunol , vol.13 , pp. 35-43
    • Chang, P.P.1
  • 36
    • 84886673181 scopus 로고    scopus 로고
    • Steady-state pro-duction of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells
    • Lee Y.J., Holzapfel K.L., Zhu J., Jameson S.C., & Hogquist K.A. Steady-state pro-duction of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells. Nat. Immunol. 14, 1146-1154 (2013
    • (2013) Nat. Immunol , vol.14 , pp. 1146-1154
    • Lee, Y.J.1    Holzapfel, K.L.2    Zhu, J.3    Jameson, S.C.4    Hogquist, K.A.5
  • 37
    • 34249059942 scopus 로고    scopus 로고
    • Identification of an IL-17-producing NK1.1neg iNKT cell popula-tion involved in airway neutrophilia
    • Michel M.L., et al. Identification of an IL-17-producing NK1.1neg iNKT cell popula-tion involved in airway neutrophilia. J. Exp. Med. 204, 995-1001 (2007
    • (2007) J. Exp. Med , vol.204 , pp. 995-1001
    • Michel, M.L.1
  • 38
    • 84907008497 scopus 로고    scopus 로고
    • IL-10-producing NKT10 cells are a distinct regulatory invariant NKT cell subset
    • Sag D., Krause P., Hedrick C.C., Kronenberg M., & Wingender G. IL-10-producing NKT10 cells are a distinct regulatory invariant NKT cell subset. J. Clin. Invest. 124, 3725-3740 (2014
    • (2014) J. Clin. Invest , vol.124 , pp. 3725-3740
    • Sag, D.1    Krause, P.2    Hedrick, C.C.3    Kronenberg, M.4    Wingender, G.5
  • 39
    • 83755166409 scopus 로고    scopus 로고
    • Invariant natural killer T cells direct B cell responses to cognate lipid antigen in an IL-21-dependent manner
    • King I.L., et al. Invariant natural killer T cells direct B cell responses to cognate lipid antigen in an IL-21-dependent manner. Nat. Immunol. 13, 44-50 (2012
    • (2012) Nat. Immunol , vol.13 , pp. 44-50
    • King, I.L.1
  • 40
    • 79851515703 scopus 로고    scopus 로고
    • Induction of NKT cell-specific immune responses in cancer tis-sues after NKT cell-targeted adoptive immunotherapy
    • Yamasaki K., et al. Induction of NKT cell-specific immune responses in cancer tis-sues after NKT cell-targeted adoptive immunotherapy. Clin. Immunol. 138, 255-265 (2011
    • (2011) Clin. Immunol , vol.138 , pp. 255-265
    • Yamasaki, K.1
  • 41
    • 0345167831 scopus 로고    scopus 로고
    • Superior protection against malaria and melanoma metastases by a C-glycoside analogue of the natural killer T cell ligand a-galactosylceramide
    • Schmieg J., Yang G., Franck R.W., & Tsuji M. Superior protection against malaria and melanoma metastases by a C-glycoside analogue of the natural killer T cell ligand a-galactosylceramide. J. Exp. Med. 198, 1631-1641 (2003
    • (2003) J. Exp. Med , vol.198 , pp. 1631-1641
    • Schmieg, J.1    Yang, G.2    Franck, R.W.3    Tsuji, M.4
  • 42
    • 0035807302 scopus 로고    scopus 로고
    • A synthetic glycolipid prevents autoim-mune encephalomyelitis by inducing TH2 bias of natural killer T cells
    • Miyamoto K., Miyake S., & Yamamura T. A synthetic glycolipid prevents autoim-mune encephalomyelitis by inducing TH2 bias of natural killer T cells. Nature 413, 531-534 (2001
    • (2001) Nature , vol.413 , pp. 531-534
    • Miyamoto, K.1    Miyake, S.2    Yamamura, T.3
  • 43
    • 84864116698 scopus 로고    scopus 로고
    • Lower TCR repertoire diversity in Traj18-deficient mice
    • Bedel R., et al. Lower TCR repertoire diversity in Traj18-deficient mice. Nat. Immunol. 13, 705-706 (2012
    • (2012) Nat. Immunol , vol.13 , pp. 705-706
    • Bedel, R.1
  • 44
    • 84937812406 scopus 로고    scopus 로고
    • A new mouse strain for the analysis of invariant NKT cell function
    • Chandra S., et al. A new mouse strain for the analysis of invariant NKT cell function. Nat. Immunol. 16, 799-800 (2015
    • (2015) Nat. Immunol , vol.16 , pp. 799-800
    • Chandra, S.1
  • 45
    • 1842682026 scopus 로고    scopus 로고
    • Prevention of autoimmunity by targeting a distinct, noninvariant CD1d-reactive T cell population reactive to sulfatide
    • Jahng A., et al. Prevention of autoimmunity by targeting a distinct, noninvariant CD1d-reactive T cell population reactive to sulfatide. J. Exp. Med. 199, 947-957 (2004
    • (2004) J. Exp. Med , vol.199 , pp. 947-957
    • Jahng, A.1
  • 46
    • 29144484782 scopus 로고    scopus 로고
    • A nonclassical non-Va14Ja18 CD1d-restricted (type II) NKT cell is sufficient for down-regulation of tumor immunosurveillance
    • Terabe M., et al. A nonclassical non-Va14Ja18 CD1d-restricted (type II) NKT cell is sufficient for down-regulation of tumor immunosurveillance. J. Exp. Med. 202, 1627-1633 (2005
    • (2005) J. Exp. Med , vol.202 , pp. 1627-1633
    • Terabe, M.1
  • 47
    • 36049022618 scopus 로고    scopus 로고
    • Cross-regulation between type i and type II NKT cells in regulat-ing tumor immunity: A new immunoregulatory axis
    • Ambrosino E., et al. Cross-regulation between type I and type II NKT cells in regulat-ing tumor immunity: a new immunoregulatory axis. J. Immunol. 179, 5126-5136 (2007
    • (2007) J. Immunol , vol.179 , pp. 5126-5136
    • Ambrosino, E.1
  • 49
    • 51649127569 scopus 로고    scopus 로고
    • Inflammation-associated lysophospholipids as ligands for CD1d-restricted T cells in human cancer
    • Chang D.H., et al. Inflammation-associated lysophospholipids as ligands for CD1d-restricted T cells in human cancer. Blood 112, 1308-1316 (2008
    • (2008) Blood , vol.112 , pp. 1308-1316
    • Chang, D.H.1
  • 50
    • 84873208755 scopus 로고    scopus 로고
    • Recognition of microbial and mammalian phospholipid antigens by NKT cells with diverse TCRs
    • Tatituri R.V., et al. Recognition of microbial and mammalian phospholipid antigens by NKT cells with diverse TCRs. Proc. Natl. Acad. Sci. USA 110, 1827-1832 (2013
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. 1827-1832
    • Tatituri, R.V.1
  • 51
    • 84863707404 scopus 로고    scopus 로고
    • Hepatitis B virus-induced lipid alterations contribute to natural killer T cell-dependent protective immunity
    • Zeissig S., et al. Hepatitis B virus-induced lipid alterations contribute to natural killer T cell-dependent protective immunity. Nat. Med. 18, 1060-1068 (2012
    • (2012) Nat. Med , vol.18 , pp. 1060-1068
    • Zeissig, S.1
  • 52
    • 4544346543 scopus 로고    scopus 로고
    • CD1d-restricted T cell activation by nonlipidic small molecules
    • Van Rhijn I., et al. CD1d-restricted T cell activation by nonlipidic small molecules. Proc. Natl. Acad. Sci. USA 101, 13578-13583 (2004
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 13578-13583
    • Van Rhijn, I.1
  • 53
    • 0035889883 scopus 로고    scopus 로고
    • Cutting edge: A major fraction of human bone marrow lymphocytes are Th2-like CD1d-reactive T cells that can suppress mixed lymphocyte responses
    • Exley M.A., et al. Cutting edge: A major fraction of human bone marrow lymphocytes are Th2-like CD1d-reactive T cells that can suppress mixed lymphocyte responses. J. Immunol. 167, 5531-5534 (2001
    • (2001) J. Immunol , vol.167 , pp. 5531-5534
    • Exley, M.A.1
  • 54
    • 79951796594 scopus 로고    scopus 로고
    • High-frequency and adaptive-like dynamics of human CD1 self-reactive T cells
    • de Lalla C., et al. High-frequency and adaptive-like dynamics of human CD1 self-reactive T cells. Eur. J. Immunol. 41, 602-610 (2011
    • (2011) Eur. J. Immunol , vol.41 , pp. 602-610
    • De Lalla, C.1
  • 55
    • 0028588920 scopus 로고
    • Recognition of a lipid antigen by CD1-restricted ab+ T cells
    • Beckman E.M., et al. Recognition of a lipid antigen by CD1-restricted ab+ T cells. Nature 372, 691-694 (1994
    • (1994) Nature , vol.372 , pp. 691-694
    • Beckman, E.M.1
  • 56
    • 84940105961 scopus 로고    scopus 로고
    • Donor unrestricted T cells: A shared human T cell response
    • Van Rhijn I., & Moody D. Donor unrestricted T cells: a shared human T cell response. J. Immunol. 195, 1927-1932 (2015
    • (2015) J. Immunol , vol.195 , pp. 1927-1932
    • Van Rhijn, I.1    Moody, D.2
  • 57
    • 84886050639 scopus 로고    scopus 로고
    • Cutting edge: CD1a tetramers and dextramers identify human lipopeptide-specific T cells ex vivo
    • Kasmar A.G., et al. Cutting edge: CD1a tetramers and dextramers identify human lipopeptide-specific T cells ex vivo. J. Immunol. 191, 4499-4503 (2013
    • (2013) J. Immunol , vol.191 , pp. 4499-4503
    • Kasmar, A.G.1
  • 58
    • 80054831155 scopus 로고    scopus 로고
    • CD1b tetramers bind ab T cell receptors to identify a mycobacte-rial glycolipid-reactive T cell repertoire in humans
    • Kasmar A.G., et al. CD1b tetramers bind ab T cell receptors to identify a mycobacte-rial glycolipid-reactive T cell repertoire in humans. J. Exp. Med. 208, 1741-1747 (2011
    • (2011) J. Exp. Med , vol.208 , pp. 1741-1747
    • Kasmar, A.G.1
  • 59
    • 84878629559 scopus 로고    scopus 로고
    • CD1c tetramers detect ex vivo T cell responses to processed phospho-mycoketide antigens
    • Ly D., et al. CD1c tetramers detect ex vivo T cell responses to processed phospho-mycoketide antigens. J. Exp. Med. 210, 729-741 (2013
    • (2013) J. Exp. Med , vol.210 , pp. 729-741
    • Ly, D.1
  • 60
    • 84879377957 scopus 로고    scopus 로고
    • A conserved human T cell population targets mycobacterial antigens presented by CD1b
    • Van Rhijn I., et al. A conserved human T cell population targets mycobacterial antigens presented by CD1b. Nat. Immunol. 14, 706-713 (2013
    • (2013) Nat. Immunol , vol.14 , pp. 706-713
    • Van Rhijn, I.1
  • 61
    • 84899539572 scopus 로고    scopus 로고
    • TCR bias and affinity define two compartments of the CD1b-glycolipid-specific T cell repertoire
    • Van Rhijn I., et al. TCR bias and affinity define two compartments of the CD1b-glycolipid-specific T cell repertoire. J. Immunol. 192, 4054-4060 (2014
    • (2014) J. Immunol , vol.192 , pp. 4054-4060
    • Van Rhijn, I.1
  • 62
    • 82755167981 scopus 로고    scopus 로고
    • Discovery of deoxyceramides and diacylglycerols as CD1b scaffold lipids among diverse groove-blocking lipids of the human CD1 system
    • Huang S., et al. Discovery of deoxyceramides and diacylglycerols as CD1b scaffold lipids among diverse groove-blocking lipids of the human CD1 system. Proc. Natl. Acad. Sci. USA 108, 19335-19340 (2011
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 19335-19340
    • Huang, S.1
  • 63
    • 84910140815 scopus 로고    scopus 로고
    • Discovery of invariant T cells by next-generation sequencing of the human TCR a-chain repertoire
    • van Schaik B., et al. Discovery of invariant T cells by next-generation sequencing of the human TCR a-chain repertoire. J. Immunol. 193, 5338-5344 (2014
    • (2014) J. Immunol , vol.193 , pp. 5338-5344
    • Van Schaik, B.1
  • 64
    • 78449298644 scopus 로고    scopus 로고
    • CD1a-autoreactive T cells are a normal component of the human ab T cell repertoire
    • de Jong A., et al. CD1a-autoreactive T cells are a normal component of the human ab T cell repertoire. Nat. Immunol. 11, 1102-1109 (2010
    • (2010) Nat. Immunol , vol.11 , pp. 1102-1109
    • De Jong, A.1
  • 65
    • 84892799782 scopus 로고    scopus 로고
    • CD1a-autoreactive T cells recognize natural skin oils that function as headless antigens
    • de Jong A., et al. CD1a-autoreactive T cells recognize natural skin oils that function as headless antigens. Nat. Immunol. 15, 177-185 (2014
    • (2014) Nat. Immunol , vol.15 , pp. 177-185
    • De Jong, A.1
  • 66
    • 84922746478 scopus 로고    scopus 로고
    • Bee venom processes human skin lipids for presentation by CD1a
    • Bourgeois E.A., et al. Bee venom processes human skin lipids for presentation by CD1a. J. Exp. Med. 212, 149-163 (2015
    • (2015) J. Exp. Med , vol.212 , pp. 149-163
    • Bourgeois, E.A.1
  • 67
    • 0024444653 scopus 로고
    • Recognition of cluster of differentiation 1 antigens by human CD4-CD8- cytolytic T lymphocytes
    • Porcelli S., et al. Recognition of cluster of differentiation 1 antigens by human CD4-CD8- cytolytic T lymphocytes. Nature 341, 447-450 (1989
    • (1989) Nature , vol.341 , pp. 447-450
    • Porcelli, S.1
  • 68
    • 84903754024 scopus 로고    scopus 로고
    • A novel self-lipid antigen targets human T cells against CD1c+ leukemias
    • Lepore M., et al. A novel self-lipid antigen targets human T cells against CD1c+ leukemias. J. Exp. Med. 211, 1363-1377 (2014
    • (2014) J. Exp. Med , vol.211 , pp. 1363-1377
    • Lepore, M.1
  • 69
    • 84927661328 scopus 로고    scopus 로고
    • T cell antigen receptor recognition of antigen-presenting molecules
    • Rossjohn J., et al. T cell antigen receptor recognition of antigen-presenting molecules. Annu. Rev. Immunol. 33, 169-200 (2015
    • (2015) Annu. Rev. Immunol , vol.33 , pp. 169-200
    • Rossjohn, J.1
  • 70
    • 0037434974 scopus 로고    scopus 로고
    • Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1
    • Treiner E., et al. Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1. Nature 422, 164-169 (2003
    • (2003) Nature , vol.422 , pp. 164-169
    • Treiner, E.1
  • 71
    • 84918836018 scopus 로고    scopus 로고
    • Mucosal-associated invariant T-cells: New players in anti-bacterial immunity
    • Ussher J.E., Klenerman P., & Willberg C.B. Mucosal-associated invariant T-cells: new players in anti-bacterial immunity. Front. Immunol. 5, 450 (2014
    • (2014) Front. Immunol , vol.5 , pp. 450
    • Ussher, J.E.1    Klenerman, P.2    Willberg, C.B.3
  • 72
    • 84885981736 scopus 로고    scopus 로고
    • Antigen-loaded MR1 tetramers define T cell receptor heteroge-neity in mucosal-associated invariant T cells
    • Reantragoon R., et al. Antigen-loaded MR1 tetramers define T cell receptor heteroge-neity in mucosal-associated invariant T cells. J. Exp. Med. 210, 2305-2320 (2013
    • (2013) J. Exp. Med , vol.210 , pp. 2305-2320
    • Reantragoon, R.1
  • 73
    • 84905118556 scopus 로고    scopus 로고
    • MR1-restricted MAIT cells display ligand discrimination and patho-gen selectivity through distinct T cell receptor usage
    • Gold M.C., et al. MR1-restricted MAIT cells display ligand discrimination and patho-gen selectivity through distinct T cell receptor usage. J. Exp. Med. 211, 1601-1610 (2014
    • (2014) J. Exp. Med , vol.211 , pp. 1601-1610
    • Gold, M.C.1
  • 74
    • 84900842237 scopus 로고    scopus 로고
    • Parallel T-cell cloning and deep sequencing of human MAIT cells reveal stable oligoclonal TCRb repertoire
    • Lepore M., et al. Parallel T-cell cloning and deep sequencing of human MAIT cells reveal stable oligoclonal TCRb repertoire. Nat. Commun. 5, 3866 (2014
    • (2014) Nat. Commun , vol.5 , pp. 3866
    • Lepore, M.1
  • 75
    • 84944872887 scopus 로고    scopus 로고
    • Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers
    • Rahimpour A., et al. Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers. J. Exp. Med. 212, 1095-1108 (2015
    • (2015) J. Exp. Med , vol.212 , pp. 1095-1108
    • Rahimpour, A.1
  • 76
    • 79251585935 scopus 로고    scopus 로고
    • Human mait cells are xenobiotic-resistant, tissue-targeted, cd161hi il-17-secreting t cells
    • Dusseaux M., et al. Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells. Blood 117, 1250-1259 (2011
    • (2011) Blood , vol.117 , pp. 1250-1259
    • Dusseaux, M.1
  • 77
    • 77954914800 scopus 로고    scopus 로고
    • Antimicrobial activity of mucosal-associated invariant T cells
    • Le Bourhis L., et al. Antimicrobial activity of mucosal-associated invariant T cells. Nat. Immunol. 11, 701-708 (2010
    • (2010) Nat. Immunol , vol.11 , pp. 701-708
    • Le Bourhis, L.1
  • 78
    • 77954701928 scopus 로고    scopus 로고
    • Human mucosal associated invariant T cells detect bacterially infected cells
    • Gold M.C., et al. Human mucosal associated invariant T cells detect bacterially infected cells. PLoS Biol. 8, e1000407 (2010
    • (2010) Plos Biol , vol.8 , pp. e1000407
    • Gold, M.C.1
  • 79
    • 84900551126 scopus 로고    scopus 로고
    • T-cell activation by transitory neo-antigens derived from distinct microbial pathways
    • Corbett A.J., et al. T-cell activation by transitory neo-antigens derived from distinct microbial pathways. Nature 509, 361-365 (2014
    • (2014) Nature , vol.509 , pp. 361-365
    • Corbett, A.J.1
  • 80
    • 84905122431 scopus 로고    scopus 로고
    • A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells
    • Eckle S.B., et al. A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells. J. Exp. Med. 211, 1585-1600 (2014
    • (2014) J. Exp. Med , vol.211 , pp. 1585-1600
    • Eckle, S.B.1
  • 81
    • 84870284140 scopus 로고    scopus 로고
    • MR1 presents microbial vitamin B metabolites to MAIT cells
    • Kjer-Nielsen L., et al. MR1 presents microbial vitamin B metabolites to MAIT cells. Nature 491, 717-723 (2012
    • (2012) Nature , vol.491 , pp. 717-723
    • Kjer-Nielsen, L.1
  • 82
    • 84880288515 scopus 로고    scopus 로고
    • Recognition of vitamin B metabolites by mucosal-associated invariant T cells
    • Patel O., et al. Recognition of vitamin B metabolites by mucosal-associated invariant T cells. Nat. Commun. 4, 2142 (2013
    • (2013) Nat. Commun , vol.4 , pp. 2142
    • Patel, O.1
  • 83
    • 84929094958 scopus 로고    scopus 로고
    • In vitro and in vivo analysis of the Gram-negative bacteria-derived riboflavin precursor derivatives activating mouse MAIT Cells
    • Soudais C., et al. In vitro and in vivo analysis of the Gram-negative bacteria-derived riboflavin precursor derivatives activating mouse MAIT Cells. J. Immunol. 194, 4641-4649 (2015
    • (2015) J. Immunol , vol.194 , pp. 4641-4649
    • Soudais, C.1
  • 84
    • 84882380657 scopus 로고    scopus 로고
    • Mait cells are critical for optimal mucosal immune responses during in vivo pulmonary bacterial infection
    • Meierovics A., Yankelevich W.J., & Cowley S.C. MAIT cells are critical for optimal mucosal immune responses during in vivo pulmonary bacterial infection. Proc. Natl. Acad. Sci. USA 110, E3119-E3128 (2013
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. E3119-E3128
    • Meierovics, A.1    Yankelevich, W.J.2    Cowley, S.C.3
  • 85
    • 84874085954 scopus 로고    scopus 로고
    • Activation, exhaustion, and persistent decline of the antimi-crobial mr1-restricted mait-cell population in chronic hiv-1 infection
    • Leeansyah E., et al. Activation, exhaustion, and persistent decline of the antimi-crobial MR1-restricted MAIT-cell population in chronic HIV-1 infection. Blood 121, 1124-1135 (2013
    • (2013) Blood , vol.121 , pp. 1124-1135
    • Leeansyah, E.1
  • 86
    • 84922649275 scopus 로고    scopus 로고
    • Mait cells are depleted early but retain functional cytokine expression in hiv infection
    • Fernandez C.S., et al. MAIT cells are depleted early but retain functional cytokine expression in HIV infection. Immunol. Cell Biol. 93, 177-188 (2015
    • (2015) Immunol. Cell Biol , vol.93 , pp. 177-188
    • Fernandez, C.S.1
  • 87
    • 84940743009 scopus 로고    scopus 로고
    • Arming of mait cell cytolytic antimicrobial activity is induced by il-7 and defective in hiv-1 infection
    • Leeansyah E., et al. Arming of MAIT cell cytolytic antimicrobial activity is induced by IL-7 and defective in HIV-1 infection. PLoS Pathog. 11, e1005072 (2015
    • (2015) Plos Pathog , vol.11 , pp. e1005072
    • Leeansyah, E.1
  • 88
    • 84892453502 scopus 로고    scopus 로고
    • CD161++ CD8+ T cells, including the MAIT cell subset, are specifi-cally activated by IL-12+IL-18 in a TCR-independent manner
    • Ussher J.E., et al. CD161++ CD8+ T cells, including the MAIT cell subset, are specifi-cally activated by IL-12+IL-18 in a TCR-independent manner. Eur. J. Immunol. 44, 195-203 (2014
    • (2014) Eur. J. Immunol , vol.44 , pp. 195-203
    • Ussher, J.E.1
  • 90
    • 84897937905 scopus 로고    scopus 로고
    • Innate mucosal-associated invariant t (mait) cells are activated in inflammatory bowel diseases
    • Serriari N.E., et al. Innate mucosal-associated invariant T (MAIT) cells are activated in inflammatory bowel diseases. Clin. Exp. Immunol. 176, 266-274 (2014
    • (2014) Clin. Exp. Immunol , vol.176 , pp. 266-274
    • Serriari, N.E.1
  • 91
    • 84926318323 scopus 로고    scopus 로고
    • Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients
    • Magalhaes I., et al. Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients. J. Clin. Invest. 125, 1752-1762 (2015
    • (2015) J. Clin. Invest , vol.125 , pp. 1752-1762
    • Magalhaes, I.1
  • 92
    • 84909959109 scopus 로고    scopus 로고
    • The IL-17A-producing CD8 T cell population in psoriatic lesional skin comprises mucosa-associated invariant T cells and conventional T cells
    • Teunissen M.B., et al. The IL-17A-producing CD8 T cell population in psoriatic lesional skin comprises mucosa-associated invariant T cells and conventional T cells. J. Invest. Dermatol. 134, 2898-2907 (2014
    • (2014) J. Invest. Dermatol , vol.134 , pp. 2898-2907
    • Teunissen, M.B.1
  • 93
    • 84907487373 scopus 로고    scopus 로고
    • Mucosal-associated invariant T cell deficiency in systemic lupus erythematosus
    • Cho Y.N., et al. Mucosal-associated invariant T cell deficiency in systemic lupus erythematosus. J. Immunol. 193, 3891-3901 (2014
    • (2014) J. Immunol , vol.193 , pp. 3891-3901
    • Cho, Y.N.1
  • 94
    • 84907835420 scopus 로고    scopus 로고
    • Reduced mucosal associated invariant T-cells are associated with increased disease severity and Pseudomonas aeruginosa infection in cystic fibrosis
    • Smith D.J., Hill G.R., Bell S.C., & Reid D.W. Reduced mucosal associated invariant T-cells are associated with increased disease severity and Pseudomonas aeruginosa infection in cystic fibrosis. PLoS ONE 9, e109891 (2014
    • (2014) Plos One , vol.9 , pp. e109891
    • Smith, D.J.1    Hill, G.R.2    Bell, S.C.3    Reid, D.W.4
  • 95
    • 84896966923 scopus 로고    scopus 로고
    • Gammadelta T cells: First line of defense and beyond
    • Chien Y.H., Meyer C., & Bonneville M. gammadelta T cells: first line of defense and beyond. Annu. Rev. Immunol. 32, 121-155 (2014
    • (2014) Annu. Rev. Immunol , vol.32 , pp. 121-155
    • Chien, Y.H.1    Meyer, C.2    Bonneville, M.3
  • 96
    • 84872930787 scopus 로고    scopus 로고
    • Six-of-the-best: Unique contributions of gd T cells to immunology
    • Vantourout P., & Hayday A. Six-of-the-best: unique contributions of gd T cells to immunology. Nat. Rev. Immunol. 13, 88-100 (2013
    • (2013) Nat. Rev. Immunol , vol.13 , pp. 88-100
    • Vantourout, P.1    Hayday, A.2
  • 97
  • 98
    • 84930572248 scopus 로고    scopus 로고
    • Dermal gd T cells-What have we learned?
    • O'Brien R.L., & Born W.K. Dermal gd T cells-What have we learned?. Cell. Immunol. 296, 62-69 (2015
    • (2015) Cell. Immunol , vol.296 , pp. 62-69
    • O'brien, R.L.1    Born, W.K.2
  • 99
    • 0024370995 scopus 로고
    • Diversity of gd T-cell recep-tors on murine intestinal intra-epithelial lymphocytes
    • Takagaki Y., DeCloux A., Bonneville M., & Tonegawa S. Diversity of gd T-cell recep-tors on murine intestinal intra-epithelial lymphocytes. Nature 339, 712-714 (1989
    • (1989) Nature , vol.339 , pp. 712-714
    • Takagaki, Y.1    Decloux, A.2    Bonneville, M.3    Tonegawa, S.4
  • 100
    • 0030940303 scopus 로고    scopus 로고
    • The T cell receptor repertoire of intestinal intraepithelial gd T lymphocytes is influenced by genes linked to the major histocompatibility complex and to the T cell receptor loci
    • Pereira P., Lafaille J.J., Gerber D., & Tonegawa S. The T cell receptor repertoire of intestinal intraepithelial gd T lymphocytes is influenced by genes linked to the major histocompatibility complex and to the T cell receptor loci. Proc. Natl. Acad. Sci. USA 94, 5761-5766 (1997
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 5761-5766
    • Pereira, P.1    Lafaille, J.J.2    Gerber, D.3    Tonegawa, S.4
  • 101
    • 0033567957 scopus 로고    scopus 로고
    • IL4-producing gd T cells that express a very restricted TCR reper-toire are preferentially localized in liver and spleen
    • Gerber D.J., et al. IL4-producing gd T cells that express a very restricted TCR reper-toire are preferentially localized in liver and spleen. J. Immunol. 163, 3076-3082 (1999
    • (1999) J. Immunol , vol.163 , pp. 3076-3082
    • Gerber, D.J.1
  • 102
    • 0027990765 scopus 로고
    • Homing and in situ differentia-tion of resident pulmonary lymphocytes
    • Sim G.K., Rajaserkar R., Dessing M., & Augustin A. Homing and in situ differentia-tion of resident pulmonary lymphocytes. Int. Immunol. 6, 1287-1295 (1994
    • (1994) Int. Immunol , vol.6 , pp. 1287-1295
    • Sim, G.K.1    Rajaserkar, R.2    Dessing, M.3    Augustin, A.4
  • 103
    • 0025019254 scopus 로고
    • Homing of a gd thymocyte subset with homogeneous T-cell receptors to mucosal epithelia
    • Itohara S., et al. Homing of a gd thymocyte subset with homogeneous T-cell receptors to mucosal epithelia. Nature 343, 754-757 (1990
    • (1990) Nature , vol.343 , pp. 754-757
    • Itohara, S.1
  • 104
    • 77954657540 scopus 로고    scopus 로고
    • Gd T cell subsets: A link between TCR and function?
    • O'Brien R.L., & Born W.K. gd T cell subsets: a link between TCR and function?. Semin. Immunol. 22, 193-198 (2010
    • (2010) Semin. Immunol , vol.22 , pp. 193-198
    • O'brien, R.L.1    Born, W.K.2
  • 105
    • 33646068413 scopus 로고    scopus 로고
    • Homing and function of human skin T cells and NK cells: Relevance for tumor surveillance
    • Ebert L.M., Meuter S., & Moser B. Homing and function of human skin T cells and NK cells: relevance for tumor surveillance. J. Immunol. 176, 4331-4336 (2006
    • (2006) J. Immunol , vol.176 , pp. 4331-4336
    • Ebert, L.M.1    Meuter, S.2    Moser, B.3
  • 106
    • 65549105119 scopus 로고    scopus 로고
    • A role for human skin-resident T cells in wound healing
    • Toulon A., et al. A role for human skin-resident T cells in wound healing. J. Exp. Med. 206, 743-750 (2009
    • (2009) J. Exp. Med , vol.206 , pp. 743-750
    • Toulon, A.1
  • 107
    • 0025782480 scopus 로고
    • A major fraction of human intraepithelial lymphocytes simultane-ously expresses the gd T cell receptor, the CD8 accessory molecule and preferentially uses the V1 gene segment
    • Deusch K., et al. A major fraction of human intraepithelial lymphocytes simultane-ously expresses the gd T cell receptor, the CD8 accessory molecule and preferentially uses the V1 gene segment. Eur. J. Immunol. 21, 1053-1059 (1991
    • (1991) Eur. J. Immunol , vol.21 , pp. 1053-1059
    • Deusch, K.1
  • 108
    • 84896490142 scopus 로고    scopus 로고
    • V9 and v2 t cell antigen receptor genes and butyrophilin 3 (btn3) emerged with placental mammals and are concomitantly preserved in selected species like alpaca (vicugna pacos
    • Karunakaran M.M., Gobel T.W., Starick L., Walter L., & Herrmann T. V9 and V2 T cell antigen receptor genes and butyrophilin 3 (BTN3) emerged with placental mammals and are concomitantly preserved in selected species like alpaca (Vicugna pacos). Immunogenetics 66, 243-254 (2014
    • (2014) Immunogenetics , vol.66 , pp. 243-254
    • Karunakaran, M.M.1    Gobel, T.W.2    Starick, L.3    Walter, L.4    Herrmann, T.5
  • 109
    • 0035824794 scopus 로고    scopus 로고
    • Identification of (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate as a major activator for human gd T cells in Escherichia coli
    • Hintz M., et al. Identification of (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate as a major activator for human gd T cells in Escherichia coli. FEBS Lett. 509, 317-322 (2001
    • (2001) Febs Lett , vol.509 , pp. 317-322
    • Hintz, M.1
  • 110
    • 84939513492 scopus 로고    scopus 로고
    • Sensing of pyrophosphate metabolites by V9V2 T cells
    • Gu S., Nawrocka W., & Adams E.J. Sensing of pyrophosphate metabolites by V9V2 T cells. Front. Immunol. 5, 688 (2014
    • (2014) Front. Immunol , vol.5 , pp. 688
    • Gu, S.1    Nawrocka, W.2    Adams, E.J.3
  • 111
    • 0010159927 scopus 로고    scopus 로고
    • Human gd T cells recognize alkylamines derived from microbes, edible plants, and tea: Implications for innate immunity
    • Bukowski J.F., Morita C.T., & Brenner M.B. Human gd T cells recognize alkylamines derived from microbes, edible plants, and tea: implications for innate immunity. Immunity 11, 57-65 (1999
    • (1999) Immunity , vol.11 , pp. 57-65
    • Bukowski, J.F.1    Morita, C.T.2    Brenner, M.B.3
  • 112
    • 0029073751 scopus 로고
    • Natural and synthetic non-peptide antigens recognized by human gd T cells
    • Tanaka Y., et al. Natural and synthetic non-peptide antigens recognized by human gd T cells. Nature 375, 155-158 (1995
    • (1995) Nature , vol.375 , pp. 155-158
    • Tanaka, Y.1
  • 113
    • 0032576633 scopus 로고    scopus 로고
    • Structure of the -Rfvn1 domain of a human gd T-cell antigen receptor
    • Li H., et al. Structure of the V domain of a human gd T-cell antigen receptor. Nature 391, 502-506 (1998
    • (1998) Nature , vol.391 , pp. 502-506
    • Li, H.1
  • 115
    • 84883147590 scopus 로고    scopus 로고
    • Butyrophilin 3A1 binds phosphorylated antigens and stimulates human gd T cells
    • Vavassori S., et al. Butyrophilin 3A1 binds phosphorylated antigens and stimulates human gd T cells. Nat. Immunol. 14, 908-916 (2013
    • (2013) Nat. Immunol , vol.14 , pp. 908-916
    • Vavassori, S.1
  • 116
    • 84899121545 scopus 로고    scopus 로고
    • The intracellular B30.2 domain of butyrophilin 3A1 binds phos-phoantigens to mediate activation of human V9V2 T cells
    • Sandstrom A., et al. The intracellular B30.2 domain of butyrophilin 3A1 binds phos-phoantigens to mediate activation of human V9V2 T cells. Immunity 40, 490-500 (2014
    • (2014) Immunity , vol.40 , pp. 490-500
    • Sandstrom, A.1
  • 117
    • 84924388810 scopus 로고    scopus 로고
    • Activation of human gd T cells by cytosolic interactions of BTN3A1 with soluble phosphoantigens and the cytoskeletal adaptor periplakin
    • Rhodes D.A., et al. Activation of human gd T cells by cytosolic interactions of BTN3A1 with soluble phosphoantigens and the cytoskeletal adaptor periplakin. J. Immunol. 194, 2390-2398 (2015
    • (2015) J. Immunol , vol.194 , pp. 2390-2398
    • Rhodes, D.A.1
  • 118
    • 84865419573 scopus 로고    scopus 로고
    • Cytomegalovirus and tumor stress surveillance by binding of a human gd T cell antigen receptor to endothelial protein C receptor
    • Willcox C.R., et al. Cytomegalovirus and tumor stress surveillance by binding of a human gd T cell antigen receptor to endothelial protein C receptor. Nat. Immunol. 13, 872-879 (2012
    • (2012) Nat. Immunol , vol.13 , pp. 872-879
    • Willcox, C.R.1
  • 119
    • 0034689029 scopus 로고    scopus 로고
    • Self-recognition of CD1 by gd T cells: Implications for innate immunity
    • Spada F.M., et al. Self-recognition of CD1 by gd T cells: implications for innate immunity. J. Exp. Med. 191, 937-948 (2000
    • (2000) J. Exp. Med , vol.191 , pp. 937-948
    • Spada, F.M.1
  • 120
    • 84886726570 scopus 로고    scopus 로고
    • CD1d-lipid antigen recognition by the gd TCR
    • Uldrich A.P., et al. CD1d-lipid antigen recognition by the gd TCR. Nat. Immunol. 14, 1137-1145 (2013
    • (2013) Nat. Immunol , vol.14 , pp. 1137-1145
    • Uldrich, A.P.1
  • 121
    • 84865762611 scopus 로고    scopus 로고
    • The majority of CD1d-sulfatide-specific T cells in human blood use a semiinvariant V1 TCR
    • Bai L., et al. The majority of CD1d-sulfatide-specific T cells in human blood use a semiinvariant V1 TCR. Eur. J. Immunol. 42, 2505-2510 (2012
    • (2012) Eur. J. Immunol , vol.42 , pp. 2505-2510
    • Bai, L.1
  • 122
    • 0036681809 scopus 로고    scopus 로고
    • T cell antigen receptor engagement and specificity in the recognition of stress-inducible MHC class I-related chains by human epithelial gd T cells
    • Wu J., Groh V., & Spies T. T cell antigen receptor engagement and specificity in the recognition of stress-inducible MHC class I-related chains by human epithelial gd T cells. J. Immunol. 169, 1236-1240 (2002
    • (2002) J. Immunol , vol.169 , pp. 1236-1240
    • Wu, J.1    Groh, V.2    Spies, T.3
  • 123
    • 67651087317 scopus 로고    scopus 로고
    • The nkg2d ligand ulbp4 binds to tcrg9/d2 and induces cytotoxicity to tumor cells through both tcrgd and nkg2d
    • Kong Y., et al. The NKG2D ligand ULBP4 binds to TCRg9/d2 and induces cytotoxicity to tumor cells through both TCRgd and NKG2D. Blood 114, 310-317 (2009
    • (2009) Blood , vol.114 , pp. 310-317
    • Kong, Y.1
  • 124
    • 84890207005 scopus 로고    scopus 로고
    • Crystal structure of Vdelta1 T cell receptor in complex with CD1d-sulfatide shows MHC-like recognition of a self-lipid by human gd T cells
    • Luoma A.M., et al. Crystal structure of Vdelta1 T cell receptor in complex with CD1d-sulfatide shows MHC-like recognition of a self-lipid by human gd T cells. Immunity 39, 1032-1042 (2013
    • (2013) Immunity , vol.39 , pp. 1032-1042
    • Luoma, A.M.1
  • 125
    • 22944439737 scopus 로고    scopus 로고
    • Human CD1-restricted T cell recognition of lipids from pollens
    • Agea E., et al. Human CD1-restricted T cell recognition of lipids from pollens. J. Exp. Med. 202, 295-308 (2005
    • (2005) J. Exp. Med , vol.202 , pp. 295-308
    • Agea, E.1
  • 126
    • 33646153985 scopus 로고    scopus 로고
    • Recognition of pollen-derived phosphatidyl-ethanolamine by human CD1d-restricted gd T cells
    • Russano A.M., et al. Recognition of pollen-derived phosphatidyl-ethanolamine by human CD1d-restricted gd T cells. J. Allergy Clin. Immunol. 117, 1178-1184 (2006
    • (2006) J. Allergy Clin. Immunol , vol.117 , pp. 1178-1184
    • Russano, A.M.1
  • 127
    • 84879614529 scopus 로고    scopus 로고
    • Cutting edge: CD1d restriction and th1/th2/th17 cytokine secre-tion by human Vd3 T cells
    • Mangan B.A., et al. Cutting edge: CD1d restriction and th1/th2/th17 cytokine secre-tion by human Vd3 T cells. J. Immunol. 191, 30-34 (2013
    • (2013) J. Immunol , vol.191 , pp. 30-34
    • Mangan, B.A.1
  • 128
    • 84866483674 scopus 로고    scopus 로고
    • Gd T cells recognize a microbial encoded B cell antigen to initiate a rapid antigen-specific interleukin-17 response
    • Zeng X., et al. gd T cells recognize a microbial encoded B cell antigen to initiate a rapid antigen-specific interleukin-17 response. Immunity 37, 524-534 (2012
    • (2012) Immunity , vol.37 , pp. 524-534
    • Zeng, X.1
  • 129
    • 84862297455 scopus 로고    scopus 로고
    • Target specificity of an autoreactive pathogenic human gd-T cell receptor in myositis
    • Bruder J., et al. Target specificity of an autoreactive pathogenic human gd-T cell receptor in myositis. J. Biol. Chem. 287, 20986-20995 (2012
    • (2012) J. Biol. Chem , vol.287 , pp. 20986-20995
    • Bruder, J.1
  • 130
    • 20644439105 scopus 로고    scopus 로고
    • MHC class Ib molecules bridge innate and acquired immunity
    • Rodgers J.R., & Cook R.G. MHC class Ib molecules bridge innate and acquired immunity. Nat. Rev. Immunol. 5, 459-471 (2005
    • (2005) Nat. Rev. Immunol , vol.5 , pp. 459-471
    • Rodgers, J.R.1    Cook, R.G.2
  • 131
    • 54049123706 scopus 로고    scopus 로고
    • The major histocompat-ibility complex class ib molecule hla-e at the interface between innate and adaptive immunity
    • Sullivan L.C., Clements C.S., Rossjohn J., & Brooks A.G. The major histocompat-ibility complex class Ib molecule HLA-E at the interface between innate and adaptive immunity. Tissue Antigens 72, 415-424 (2008
    • (2008) Tissue Antigens , vol.72 , pp. 415-424
    • Sullivan, L.C.1    Clements, C.S.2    Rossjohn, J.3    Brooks, A.G.4
  • 132
    • 0037087403 scopus 로고    scopus 로고
    • Recognition of nonclassical HLA class i antigens by gd T cells during pregnancy
    • Barakonyi A., et al. Recognition of nonclassical HLA class I antigens by gd T cells during pregnancy. J. Immunol. 168, 2683-2688 (2002
    • (2002) J. Immunol , vol.168 , pp. 2683-2688
    • Barakonyi, A.1
  • 133
    • 79251565506 scopus 로고    scopus 로고
    • Nonconventional cd8+ t cell responses to listeria infection in mice lacking mhc class ia and h2-m3
    • Cho H., Choi H.-J., Xu H., Felio K., & Wang C.-R. Nonconventional CD8+ T cell responses to listeria infection in mice lacking MHC class Ia and H2-M3. J. Immunol. 186, 489-498 (2011
    • (2011) J. Immunol , vol.186 , pp. 489-498
    • Cho, H.1    Choi, H.-J.2    Xu, H.3    Felio, K.4    Wang, C.-R.5
  • 134
    • 84927071832 scopus 로고    scopus 로고
    • Human CD8 T lymphocytes recognize Mycobacterium tuberculosis antigens presented by HLA-E during active tuberculosis and express type 2 cytokines
    • Caccamo N., et al. Human CD8 T lymphocytes recognize Mycobacterium tuberculosis antigens presented by HLA-E during active tuberculosis and express type 2 cytokines. Eur. J. Immunol. 45, 1069-1081 (2015
    • (2015) Eur. J. Immunol , vol.45 , pp. 1069-1081
    • Caccamo, N.1
  • 135
    • 84926431092 scopus 로고    scopus 로고
    • Human cd8+ t-cells recognizing peptides from mycobacterium tuberculosis (mtb) presented by hla-e have an unorthodox th2- like, multifunctional, mtb inhibitory phenotype and represent a novel human t-cell subset
    • van Meijgaarden K.E., et al. Human CD8+ T-cells recognizing peptides from Mycobacterium tuberculosis (Mtb) presented by HLA-E have an unorthodox Th2- like, multifunctional, Mtb inhibitory phenotype and represent a novel human T-cell subset. PLoS Pathog. 11, e1004671 (2015
    • (2015) Plos Pathog , vol.11 , pp. e1004671
    • Van Meijgaarden, K.E.1
  • 137
    • 0033373337 scopus 로고    scopus 로고
    • The selection of M3-restricted T cells is dependent on M3 expres-sion and presentation of N-formylated peptides in the thymus
    • Chiu N.M., et al. The selection of M3-restricted T cells is dependent on M3 expres-sion and presentation of N-formylated peptides in the thymus. J. Exp. Med. 190, 1869-1878 (1999
    • (1999) J. Exp. Med , vol.190 , pp. 1869-1878
    • Chiu, N.M.1
  • 138
    • 46949090374 scopus 로고    scopus 로고
    • An MHC class Ib-restricted CD8 T cell response confers antiviral immunity
    • Swanson P.A., et al. An MHC class Ib-restricted CD8 T cell response confers antiviral immunity. J. Exp. Med. 205, 1647-1657 (2008
    • (2008) J. Exp. Med , vol.205 , pp. 1647-1657
    • Swanson, P.A.1
  • 139
    • 17844388378 scopus 로고    scopus 로고
    • Protective immunity against disparate tumors is medi-ated by a nonpolymorphic MHC class i molecule
    • Chiang E.Y., & Stroynowski I. Protective immunity against disparate tumors is medi-ated by a nonpolymorphic MHC class I molecule. J. Immunol. 174, 5367-5374 (2005
    • (2005) J. Immunol , vol.174 , pp. 5367-5374
    • Chiang, E.Y.1    Stroynowski, I.2
  • 140
    • 84859392140 scopus 로고    scopus 로고
    • MHC class Ib-restricted CD8 T cells differ in dependence on CD4 T cell Help and CD28 costimulation over the course of mouse polyomavirus infection
    • Hofstetter A.R., et al. MHC class Ib-restricted CD8 T cells differ in dependence on CD4 T cell Help and CD28 costimulation over the course of mouse polyomavirus infection. J. Immunol. 188, 3071-3079 (2012
    • (2012) J. Immunol , vol.188 , pp. 3071-3079
    • Hofstetter, A.R.1
  • 141
    • 24644446820 scopus 로고    scopus 로고
    • Direct recognition by ab cytolytic T cells of Hfe, a MHC class Ib molecule without antigen-presenting function
    • Rohrlich P.S., et al. Direct recognition by ab cytolytic T cells of Hfe, a MHC class Ib molecule without antigen-presenting function. Proc. Natl. Acad. Sci. USA 102, 12855-12860 (2005
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 12855-12860
    • Rohrlich, P.S.1
  • 142
    • 0033621534 scopus 로고    scopus 로고
    • A population of murine gd T cells that recognize an inducible MHC class Ib molecule
    • Crowley M.P., et al. A population of murine gd T cells that recognize an inducible MHC class Ib molecule. Science 287, 314-316 (2000
    • (2000) Science , vol.287 , pp. 314-316
    • Crowley, M.P.1
  • 143
    • 0030895323 scopus 로고    scopus 로고
    • The recognition of the nonclassical major histocompatibility complex (mhc) class i molecule t10, by the gd t cell, g8
    • Crowley M.P., Reich Z., Mavaddat N., Altman J.D., & Chien Y. The recognition of the nonclassical major histocompatibility complex (MHC) class I molecule, T10, by the gd T cell, G8. J. Exp. Med. 185, 1223-1230 (1997
    • (1997) J. Exp. Med , vol.185 , pp. 1223-1230
    • Crowley, M.P.1    Reich, Z.2    Mavaddat, N.3    Altman, J.D.4    Chien, Y.5
  • 144
    • 84907996747 scopus 로고    scopus 로고
    • Efficacy of ABX196, a new NKT agonist, in prophylactic human vaccination
    • Tefit J.N., et al. Efficacy of ABX196, a new NKT agonist, in prophylactic human vaccination. Vaccine 32, 6138-6145 (2014
    • (2014) Vaccine , vol.32 , pp. 6138-6145
    • Tefit, J.N.1
  • 145
    • 78650412279 scopus 로고    scopus 로고
    • Targeting gd T lymphocytes for cancer immunotherapy: From novel mechanistic insight to clinical application
    • Gomes A.Q., Martins D.S., & Silva-Santos B. Targeting gd T lymphocytes for cancer immunotherapy: from novel mechanistic insight to clinical application. Cancer Res. 70, 10024-10027 (2010
    • (2010) Cancer Res , vol.70 , pp. 10024-10027
    • Gomes, A.Q.1    Martins, D.S.2    Silva-Santos, B.3
  • 146
    • 84923575748 scopus 로고    scopus 로고
    • Ab T cell antigen receptor recognition of CD1a presenting self lipid ligands
    • Birkinshaw R.W., et al. ab T cell antigen receptor recognition of CD1a presenting self lipid ligands. Nat. Immunol. 16, 258-266 (2015
    • (2015) Nat. Immunol , vol.16 , pp. 258-266
    • Birkinshaw, R.W.1
  • 147
    • 77951242341 scopus 로고    scopus 로고
    • NKT cell responses to glycolipid activation
    • Tefit J.N., Davies G., & Serra V. NKT cell responses to glycolipid activation. Methods Mol. Biol. 626, 149-167 (2010
    • (2010) Methods Mol. Biol , vol.626 , pp. 149-167
    • Tefit, J.N.1    Davies, G.2    Serra, V.3
  • 148
    • 35748954102 scopus 로고    scopus 로고
    • Cross-presentation of glycolipid from tumor cells loaded with a-galactosylceramide leads to potent and long-lived t cell mediated immunity via dendritic cells
    • Shimizu K., Kurosawa Y., Taniguchi M., Steinman R.M., & Fujii S. Cross-presentation of glycolipid from tumor cells loaded with a-galactosylceramide leads to potent and long-lived T cell mediated immunity via dendritic cells. J. Exp. Med. 204, 2641-2653 (2007
    • (2007) J. Exp. Med , vol.204 , pp. 2641-2653
    • Shimizu, K.1    Kurosawa, Y.2    Taniguchi, M.3    Steinman, R.M.4    Fujii, S.5
  • 149
    • 68149168633 scopus 로고    scopus 로고
    • Incorporation of nkt cell-activating glycolipids enhances immunogenicity and vaccine efficacy of mycobacterium bovis bacillus calmette- guerin
    • Venkataswamy M.M., et al. Incorporation of NKT cell-activating glycolipids enhances immunogenicity and vaccine efficacy of Mycobacterium bovis bacillus Calmette- Guerin. J. Immunol. 183, 1644-1656 (2009
    • (2009) J. Immunol , vol.183 , pp. 1644-1656
    • Venkataswamy, M.M.1
  • 150
    • 84937846973 scopus 로고    scopus 로고
    • Evolving synergistic combinations of targeted immunotherapies to combat cancer
    • Melero I., et al. Evolving synergistic combinations of targeted immunotherapies to combat cancer. Nat. Rev. Cancer 15, 457-472 (2015
    • (2015) Nat. Rev. Cancer , vol.15 , pp. 457-472
    • Melero, I.1
  • 151
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • Pardoll D.M. The blockade of immune checkpoints in cancer immunotherapy. Nat. Rev. Cancer 12, 252-264 (2012
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 252-264
    • Pardoll, D.M.1
  • 152
    • 0025348508 scopus 로고
    • T-cell receptor-gd bearing lymphocytes in normal and inflammatory human skin
    • Dupuy P., et al. T-cell receptor-gd bearing lymphocytes in normal and inflammatory human skin. J. Invest. Dermatol. 94, 764-768 (1990
    • (1990) J. Invest. Dermatol , vol.94 , pp. 764-768
    • Dupuy, P.1
  • 153
    • 70449713763 scopus 로고    scopus 로고
    • CD1-restricted adaptive immune responses to Mycobacteria in human group 1 CD1 transgenic mice
    • Felio K., et al. CD1-restricted adaptive immune responses to Mycobacteria in human group 1 CD1 transgenic mice. J. Exp. Med. 206, 2497-2509 (2009
    • (2009) J. Exp. Med , vol.206 , pp. 2497-2509
    • Felio, K.1
  • 154
    • 79959757265 scopus 로고    scopus 로고
    • Analysis of the CD1 antigen presenting system in humanized SCID mice
    • Lockridge J.L., et al. Analysis of the CD1 antigen presenting system in humanized SCID mice. PLoS ONE 6, e21701 (2011
    • (2011) Plos One , vol.6 , pp. e21701
    • Lockridge, J.L.1
  • 155
    • 0033571445 scopus 로고    scopus 로고
    • Conservation of a CD1 multigene family in the guinea pig
    • Dascher C.C., et al. Conservation of a CD1 multigene family in the guinea pig. J. Immunol. 163, 5478-5488 (1999
    • (1999) J. Immunol , vol.163 , pp. 5478-5488
    • Dascher, C.C.1
  • 156
    • 80054831155 scopus 로고    scopus 로고
    • CD1b tetramers bind ab T cell receptors to identify a mycobacterial glycolipid-reactive T cell repertoire in humans
    • Kasmar A.G., et al. CD1b tetramers bind ab T cell receptors to identify a mycobacterial glycolipid-reactive T cell repertoire in humans. J. Exp. Med. 208, 1741-1747 (2011
    • (2011) J. Exp. Med , vol.208 , pp. 1741-1747
    • Kasmar, A.G.1
  • 157
    • 84878629559 scopus 로고    scopus 로고
    • CD1c tetramers detect ex vivo T cell responses to processed phospho-mycoketide antigens
    • Ly D., et al. CD1c tetramers detect ex vivo T cell responses to processed phospho-mycoketide antigens. J. Exp. Med. 210, 729-741 (2013
    • (2013) J. Exp. Med , vol.210 , pp. 729-741
    • Ly, D.1
  • 158
    • 18844432751 scopus 로고    scopus 로고
    • Limited cor-relation between human thymus and blood nkt cell content revealed by an ontogeny study of paired tissue samples
    • Berzins S.P., Cochrane A.D., Pellicci D.G., Smyth M.J., & Godfrey D.I. Limited cor-relation between human thymus and blood NKT cell content revealed by an ontogeny study of paired tissue samples. Eur. J. Immunol. 35, 1399-1407 (2005
    • (2005) Eur. J. Immunol , vol.35 , pp. 1399-1407
    • Berzins, S.P.1    Cochrane, A.D.2    Pellicci, D.G.3    Smyth, M.J.4    Godfrey, D.I.5
  • 159
    • 0034605065 scopus 로고    scopus 로고
    • Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers
    • Matsuda J.L., et al. Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers. J. Exp. Med. 192, 741-754 (2000
    • (2000) J. Exp. Med , vol.192 , pp. 741-754
    • Matsuda, J.L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.