Improved genome inference in the MHC using a population reference graph

Nature Genetics

Volumn 47, Issue 6, 2015, Pages 682-688

  Dilthey, Alexander ^a   Cox, Charles ^b   Iqbal, Zamin ^a   Nelson, Matthew R ^c   McVean, Gil ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HLA DQB1 ANTIGEN; HLA DRB1 ANTIGEN; HLA DRB5 ANTIGEN; HLA ANTIGEN CLASS 2;

ALLELE; ARTICLE; CHROMOSOME 6; DIPLOIDY; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HIDDEN MARKOV MODEL; HLA SYSTEM; HLA TYPING; HUMAN; HUMAN GENOME; MAJOR HISTOCOMPATIBILITY COMPLEX; MAXIMUM LIKELIHOOD METHOD; PARALOGY; POPULATION REFERENCE GRAPH; PRIORITY JOURNAL; PSEUDOGENE; SEGMENTAL DUPLICATION; SIMULATION; SINGLE NUCLEOTIDE POLYMORPHISM; ALGORITHM; BIOLOGICAL MODEL; COMPUTER SIMULATION; DNA SEQUENCE; GENETICS; GENOTYPING TECHNIQUE; STANDARD; STANDARDS;

ALGORITHMS; COMPUTER SIMULATION; GENOME, HUMAN; GENOTYPING TECHNIQUES; HAPLOTYPES; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; MODELS, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; REFERENCE STANDARDS; SEQUENCE ANALYSIS, DNA;

EID: 84930083227     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3257     Document Type: Article

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