Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation

Cell

Volumn 173, Issue 2, 2018, Pages 338-354.e15

  Malta, Tathiane M ^a,b   Sokolov, Artem ^c   Gentles, Andrew J ^d   Burzykowski, Tomasz ^e   Poisson, Laila ^a   Weinstein, John N ^f,w   Kamińska, Bożena ^g   Huelsken, Joerg ^h   Omberg, Larsson ⁱ   Gevaert, Olivier ^d   Colaprico, Antonio ^j,k   Czerwińska, Patrycja ^l   Mazurek, Sylwia ^l,m   Mishra, Lopa ⁿ   Heyn, Holger ^o   Krasnitz, Alex ^p   Godwin, Andrew K ^q,w   Lazar, Alexander J ^f,w   Caesar Johnson, Samantha J ^w   Demchok, John A ^w   Felau, Ina ^w   Kasapi, Melpomeni ^w   Ferguson, Martin L ^w   Hutter, Carolyn M ^w   Sofia, Heidi J ^w   Tarnuzzer, Roy ^w   Wang, Zhining ^w   Yang, Liming ^w   Zenklusen, Jean C ^w   Stuart, Joshua M ^r   Hoadley, Katherine A ^s,t   Wiznerowicz, Maciej ^l,u,v   Noushmehr, Houtan ^a,b   more..

^a HENRY FORD HEALTH SYSTEM   (United States)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c HARVARD MEDICAL SCHOOL   (United States)

^d STANFORD UNIVERSITY   (United States)

^e HASSELT UNIVERSITY   (Belgium)

^f UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^g NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

^h EPFL   (Switzerland)

ⁱ SAGE BIONETWORKS   (United States)

^j UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^k Interuniversity Institute of Bioinformatics in Brussels (IB)2   (Belgium)

^l POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

^m MEDICAL UNIVERSITY OF WARSAW   (Poland)

ⁿ GEORGE WASHINGTON UNIVERSITY   (United States)

^o CENTRE FOR GENOMIC REGULATION CRG   (Spain)

^p Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^q UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^r UNIVERSITY OF CALIFORNIA   (United States)

^s UNIVERSITY OF NORTH CAROLINA   (United States)

^t VAN ANDEL RESEARCH INSTITUTE   (United States)

^u GREATER POLAND CANCER CENTER   (Poland)

^v International Institute for Molecular Oncology   (Poland)

^w Julia)

more..

Author keywords

cancer stem cells; dedifferentiation; epigenomic; genomic; machine learning; pan cancer; stemness; The Cancer Genome Atlas

Indexed keywords

MESSENGER RNA; MICRORNA; TRANSCRIPTOME;

ARTICLE; CELL DEDIFFERENTIATION; CELL INFILTRATION; CONTROLLED STUDY; DNA METHYLATION; EPIGENETICS; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; MACHINE LEARNING; PHENOTYPE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; TRANSCRIPTOMICS; TUMOR MICROENVIRONMENT; CARCINOGENESIS; CYTOLOGY; GENETIC DATABASE; GENETIC EPIGENESIS; GENETICS; METABOLISM; METASTASIS; NEOPLASM; PATHOLOGY; STEM CELL;

CARCINOGENESIS; CELL DEDIFFERENTIATION; DATABASES, GENETIC; DNA METHYLATION; EPIGENESIS, GENETIC; HUMANS; MACHINE LEARNING; MICRORNAS; NEOPLASM METASTASIS; NEOPLASMS; STEM CELLS; TRANSCRIPTOME; TUMOR MICROENVIRONMENT;

EID: 85044967234     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2018.03.034     Document Type: Article

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