Acetyl-coenzyme A carboxylase alpha promotion of glucose-mediated fatty acid synthesis enhances survival of hepatocellular carcinoma in mice and patients

Hepatology

Volumn 63, Issue 4, 2016, Pages 1272-1286

  Wang, Ming Da ^a   Wu, Han ^a   Fu, Gong Bo ^a   Zhang, Hui Lu ^a   Zhou, Xu ^a   Tang, Liang ^a   Dong, Li Wei ^a,b   Qin, Chen Jie ^a   Huang, Shuai ^a   Zhao, Ling Hao ^a   Zeng, Min ^a   Wu, Meng Chao ^a   Yan, He Xin ^a,b   Wang, Hong Yang ^a,b  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b National Center for Liver Cancer   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE ALPHA; ACYLTRANSFERASE; CARNITINE PALMITOYLTRANSFERASE IA; GLUCOSE; LIGASE; LIPID; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; SHORT HAIRPIN RNA; SORAFENIB; TETRAHYDROLIPSTATIN; UNCLASSIFIED DRUG; ACETYL COENZYME A CARBOXYLASE; FATTY ACID; FATTY ACID SYNTHASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CANCER PROGNOSIS; CANCER SURVIVAL; CELL SURVIVAL; CONTROLLED STUDY; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FATTY ACID OXIDATION; FATTY ACID SYNTHESIS; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; HUMAN TISSUE; LIPOGENESIS; LIVER CELL CARCINOMA; METABOLIC STRESS; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; APOPTOSIS; COMPARATIVE STUDY; DISEASE MODEL; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; KAPLAN MEIER METHOD; LIPID METABOLISM; LIVER TUMOR; METABOLISM; MORTALITY; OXIDATIVE STRESS; PATHOLOGY; PHYSIOLOGY; PREDICTIVE VALUE; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; SURVIVAL ANALYSIS; TUMOR CELL LINE; UPREGULATION; XENOGRAFT;

ACETYL-COA CARBOXYLASE; ANIMALS; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL SURVIVAL; DISEASE MODELS, ANIMAL; FATTY ACID SYNTHASES; FATTY ACIDS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GLUCOSE; HETEROGRAFTS; HUMANS; KAPLAN-MEIER ESTIMATE; LIPID METABOLISM; LIVER NEOPLASMS; MICE; OXIDATIVE STRESS; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; SURVIVAL ANALYSIS; UP-REGULATION;

EID: 84975726280     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.28415     Document Type: Article

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