-
1
-
-
84864397350
-
Elucidation of (-)-epicatechin metabolites after ingestion of chocolate by healthy humans
-
Actis-Goretta, L., Lévèques, A., Giuffrida, F., Romanov-Michailidis, F., Viton, F., Barron, D., Duenas-Paton, M., Gonzalez-Manzano, S., Santos-Buelga, C., Williamson, G., Dionisi, F., Elucidation of (-)-epicatechin metabolites after ingestion of chocolate by healthy humans. Free Radic. Biol. Med. 53 (2012), 787–795 https://doi.org/10.1016/j.freeradbiomed.2012.05.023.
-
(2012)
Free Radic. Biol. Med.
, vol.53
, pp. 787-795
-
-
Actis-Goretta, L.1
Lévèques, A.2
Giuffrida, F.3
Romanov-Michailidis, F.4
Viton, F.5
Barron, D.6
Duenas-Paton, M.7
Gonzalez-Manzano, S.8
Santos-Buelga, C.9
Williamson, G.10
Dionisi, F.11
-
2
-
-
84884874365
-
Intestinal absorption, metabolism, and excretion of (-)-epicatechin in healthy humans assessed by using an intestinal perfusion technique
-
Actis-Goretta, L., Lévèques, A., Rein, M., Teml, A., Schäfer, C., Hofmann, U., Li, H., Schwab, M., Eichelbaum, M., Williamson, G., Intestinal absorption, metabolism, and excretion of (-)-epicatechin in healthy humans assessed by using an intestinal perfusion technique. Am. J. Clin. Nutr. 98 (2013), 924–933 https://doi.org/10.3945/ajcn.113.065789.
-
(2013)
Am. J. Clin. Nutr.
, vol.98
, pp. 924-933
-
-
Actis-Goretta, L.1
Lévèques, A.2
Rein, M.3
Teml, A.4
Schäfer, C.5
Hofmann, U.6
Li, H.7
Schwab, M.8
Eichelbaum, M.9
Williamson, G.10
-
3
-
-
23744451730
-
Heteroactivation of cytochrome P450 1A1 by teas and tea polyphenols
-
Anger, D.L., Petre, M.-A., Crankshaw, D.J., Heteroactivation of cytochrome P450 1A1 by teas and tea polyphenols. Br. J. Pharmacol. 145 (2005), 926–933 https://doi.org/10.1038/sj.bjp.0706255.
-
(2005)
Br. J. Pharmacol.
, vol.145
, pp. 926-933
-
-
Anger, D.L.1
Petre, M.-A.2
Crankshaw, D.J.3
-
4
-
-
8244264753
-
A clinical trial of the effects of dietary patterns on blood pressure
-
Appel, L.J., Moore, T.J., Obarzanek, E., Vollmer, W.M., Svetkey, L.P., Sacks, F.M., Bray, G.A., Vogt, T.M., Cutler, J.A., Windhauser, M.M., Lin, P.H., Karanja, N., DASH Collaborative Research Group. A clinical trial of the effects of dietary patterns on blood pressure. N. Engl. J. Med. 336 (1997), 1117–1124 https://doi.org/10.1056/NEJM199704173361601.
-
(1997)
N. Engl. J. Med.
, vol.336
, pp. 1117-1124
-
-
Appel, L.J.1
Moore, T.J.2
Obarzanek, E.3
Vollmer, W.M.4
Svetkey, L.P.5
Sacks, F.M.6
Bray, G.A.7
Vogt, T.M.8
Cutler, J.A.9
Windhauser, M.M.10
Lin, P.H.11
Karanja, N.12
-
5
-
-
85018726557
-
Fruit and vegetable intake and the risk of cardiovascular disease, total cancer and all-cause mortality-a systematic review and dose-response meta-analysis of prospective studies
-
Aune, D., Giovannucci, E., Boffetta, P., Fadnes, L.T., Keum, N., Norat, T., Greenwood, D.C., Riboli, E., Vatten, L.J., Tonstad, S., Fruit and vegetable intake and the risk of cardiovascular disease, total cancer and all-cause mortality-a systematic review and dose-response meta-analysis of prospective studies. Int. J. Epidemiol. 46 (2017), 1029–1056 https://doi.org/10.1093/ije/dyw319.
-
(2017)
Int. J. Epidemiol.
, vol.46
, pp. 1029-1056
-
-
Aune, D.1
Giovannucci, E.2
Boffetta, P.3
Fadnes, L.T.4
Keum, N.5
Norat, T.6
Greenwood, D.C.7
Riboli, E.8
Vatten, L.J.9
Tonstad, S.10
-
6
-
-
85038252382
-
Antioxidants: wonder drugs or quackery?
-
Azzi, A., Antioxidants: wonder drugs or quackery?. Biofactors 43 (2017), 785–788 https://doi.org/10.1002/biof.1388.
-
(2017)
Biofactors
, vol.43
, pp. 785-788
-
-
Azzi, A.1
-
7
-
-
49549112269
-
Dietary flavonoid (-)epicatechin stimulates phosphatidylinositol 3-kinase-dependent anti-oxidant response element activity and up-regulates glutathione in cortical astrocytes
-
Bahia, P.K., Rattray, M., Williams, R.J., Dietary flavonoid (-)epicatechin stimulates phosphatidylinositol 3-kinase-dependent anti-oxidant response element activity and up-regulates glutathione in cortical astrocytes. J. Neurochem. 106 (2008), 2194–2204 https://doi.org/10.1111/j.1471-4159.2008.05542.x.
-
(2008)
J. Neurochem.
, vol.106
, pp. 2194-2204
-
-
Bahia, P.K.1
Rattray, M.2
Williams, R.J.3
-
8
-
-
84925424662
-
Pharmacokinetic, partial pharmacodynamic and initial safety analysis of (-)-epicatechin in healthy volunteers
-
Barnett, C.F., Moreno-Ulloa, A., Shiva, S., Ramirez-Sanchez, I., Taub, P.R., Su, Y., Ceballos, G., Dugar, S., Schreiner, G., Villarreal, F., Pharmacokinetic, partial pharmacodynamic and initial safety analysis of (-)-epicatechin in healthy volunteers. Food Funct. 6 (2015), 824–833 https://doi.org/10.1039/c4fo00596a.
-
(2015)
Food Funct.
, vol.6
, pp. 824-833
-
-
Barnett, C.F.1
Moreno-Ulloa, A.2
Shiva, S.3
Ramirez-Sanchez, I.4
Taub, P.R.5
Su, Y.6
Ceballos, G.7
Dugar, S.8
Schreiner, G.9
Villarreal, F.10
-
9
-
-
84866975119
-
A state-of-the-art overview of the effect of metabolic conjugation on the biological activity of flavonoids
-
Beekmann, K., Actis-Goretta, L., van Bladeren, P.J., Dionisi, F., Destaillats, F., Rietjens, I.M.C.M., A state-of-the-art overview of the effect of metabolic conjugation on the biological activity of flavonoids. Food Funct. 3 (2012), 1008–1018 https://doi.org/10.1039/c2fo30065f.
-
(2012)
Food Funct.
, vol.3
, pp. 1008-1018
-
-
Beekmann, K.1
Actis-Goretta, L.2
van Bladeren, P.J.3
Dionisi, F.4
Destaillats, F.5
Rietjens, I.M.C.M.6
-
10
-
-
76949114628
-
The inhibition of xanthine oxidase by flavonoids and related compounds
-
Beiler, J.M., Martin, G.J., The inhibition of xanthine oxidase by flavonoids and related compounds. J. Biol. Chem. 192 (1951), 831–834.
-
(1951)
J. Biol. Chem.
, vol.192
, pp. 831-834
-
-
Beiler, J.M.1
Martin, G.J.2
-
11
-
-
84896140767
-
An intimate Relationship between ROS and insulin signalling: implications for antioxidant treatment of fatty liver disease
-
Besse-Patin, A., Estall, J.L., An intimate Relationship between ROS and insulin signalling: implications for antioxidant treatment of fatty liver disease. Int. J. Cell Biol., 2014, 2014, 519153 https://doi.org/10.1155/2014/519153.
-
(2014)
Int. J. Cell Biol.
, vol.2014
, pp. 519153
-
-
Besse-Patin, A.1
Estall, J.L.2
-
12
-
-
84995426957
-
Anti-inflammatory actions of (-)-epicatechin in the adipose tissue of obese mice
-
Bettaieb, A., Cremonini, E., Kang, H., Kang, J., Haj, F.G., Oteiza, P.I., Anti-inflammatory actions of (-)-epicatechin in the adipose tissue of obese mice. Int. J. Biochem. Cell Biol., 2016 https://doi.org/10.1016/j.biocel.2016.08.044.
-
(2016)
Int. J. Biochem. Cell Biol.
-
-
Bettaieb, A.1
Cremonini, E.2
Kang, H.3
Kang, J.4
Haj, F.G.5
Oteiza, P.I.6
-
13
-
-
84901054689
-
(-)-Epicatechin mitigates high-fructose-associated insulin resistance by modulating redox signaling and endoplasmic reticulum stress
-
Bettaieb, A., Vazquez Prieto, M.A., Rodriguez Lanzi, C., Miatello, R.M., Haj, F.G., Fraga, C.G., Oteiza, P.I., (-)-Epicatechin mitigates high-fructose-associated insulin resistance by modulating redox signaling and endoplasmic reticulum stress. Free Radic. Biol. Med. 72 (2014), 247–256 https://doi.org/10.1016/j.freeradbiomed.2014.04.011.
-
(2014)
Free Radic. Biol. Med.
, vol.72
, pp. 247-256
-
-
Bettaieb, A.1
Vazquez Prieto, M.A.2
Rodriguez Lanzi, C.3
Miatello, R.M.4
Haj, F.G.5
Fraga, C.G.6
Oteiza, P.I.7
-
14
-
-
70149091965
-
Subcellular localization of Nox4 and regulation in diabetes
-
Block, K., Gorin, Y., Abboud, H.E., Subcellular localization of Nox4 and regulation in diabetes. Proc. Natl. Acad. Sci. 106 (2009), 14385–14390 https://doi.org/10.1073/pnas.0906805106.
-
(2009)
Proc. Natl. Acad. Sci.
, vol.106
, pp. 14385-14390
-
-
Block, K.1
Gorin, Y.2
Abboud, H.E.3
-
15
-
-
85033371810
-
Absorption, metabolism, distribution and excretion of (-)-epicatechin: a review of recent findings
-
Borges, G., Ottaviani, J.I., van der Hooft, J.J.J., Schroeter, H., Crozier, A., Absorption, metabolism, distribution and excretion of (-)-epicatechin: a review of recent findings. Mol. Aspect. Med., 2017 https://doi.org/10.1016/j.mam.2017.11.002.
-
(2017)
Mol. Aspect. Med.
-
-
Borges, G.1
Ottaviani, J.I.2
van der Hooft, J.J.J.3
Schroeter, H.4
Crozier, A.5
-
16
-
-
0021288856
-
Determination of the production of superoxide radicals and hydrogen peroxide in mitochondria
-
Boveris, A., Determination of the production of superoxide radicals and hydrogen peroxide in mitochondria. Methods Enzymol. 105 (1984), 429–435.
-
(1984)
Methods Enzymol.
, vol.105
, pp. 429-435
-
-
Boveris, A.1
-
17
-
-
0015882341
-
The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen
-
Boveris, A., Chance, B., The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. Biochem. J. 134 (1973), 707–716.
-
(1973)
Biochem. J.
, vol.134
, pp. 707-716
-
-
Boveris, A.1
Chance, B.2
-
18
-
-
84893825263
-
Nox family NADPH oxidases in mechano-transduction: mechanisms and consequences
-
Brandes, R.P., Weissmann, N., Schröder, K., Nox family NADPH oxidases in mechano-transduction: mechanisms and consequences. Antioxidants Redox Signal. 20 (2014), 887–898 https://doi.org/10.1089/ars.2013.5414.
-
(2014)
Antioxidants Redox Signal.
, vol.20
, pp. 887-898
-
-
Brandes, R.P.1
Weissmann, N.2
Schröder, K.3
-
19
-
-
33644599022
-
Cocoa intake, blood pressure, and cardiovascular mortality: the zutphen elderly study
-
Buijsse, B., Feskens, E.J.M., Kok, F.J., Kromhout, D., Cocoa intake, blood pressure, and cardiovascular mortality: the zutphen elderly study. Arch. Intern. Med. 166 (2006), 411–417 https://doi.org/10.1001/archinte.166.4.411.
-
(2006)
Arch. Intern. Med.
, vol.166
, pp. 411-417
-
-
Buijsse, B.1
Feskens, E.J.M.2
Kok, F.J.3
Kromhout, D.4
-
20
-
-
84966378395
-
Modifications in nitric oxide and superoxide anion metabolism induced by fructose overload in rat heart are prevented by (-)-epicatechin
-
Calabró V., Piotrkowski, B., Fischerman, L., Vazquez Prieto, M.A., Galleano, M., Fraga, C.G., Modifications in nitric oxide and superoxide anion metabolism induced by fructose overload in rat heart are prevented by (-)-epicatechin. Food Funct. 7 (2016), 1876–1883 https://doi.org/10.1039/c6fo00048g.
-
(2016)
Food Funct.
, vol.7
, pp. 1876-1883
-
-
Calabró, V.1
Piotrkowski, B.2
Fischerman, L.3
Vazquez Prieto, M.A.4
Galleano, M.5
Fraga, C.G.6
-
21
-
-
84917707357
-
Molecular mechanisms of the microsomal mixed function oxidases and biological and pathological implications
-
Cederbaum, A.I., Molecular mechanisms of the microsomal mixed function oxidases and biological and pathological implications. Redox Biol. 4 (2015), 60–73 https://doi.org/10.1016/j.redox.2014.11.008.
-
(2015)
Redox Biol.
, vol.4
, pp. 60-73
-
-
Cederbaum, A.I.1
-
22
-
-
84900546063
-
Resveratrol decreases fructose-induced oxidative stress, mediated by NADPH oxidase via an AMPK-dependent mechanism
-
Cheng, P.-W., Ho, W.-Y., Su, Y.-T., Lu, P.-J., Chen, B.-Z., Cheng, W.-H., Lu, W.-H., Sun, G.-C., Yeh, T.-C., Hsiao, M., Tseng, C.-J., Resveratrol decreases fructose-induced oxidative stress, mediated by NADPH oxidase via an AMPK-dependent mechanism. Br. J. Pharmacol. 171 (2014), 2739–2750 https://doi.org/10.1111/bph.12648.
-
(2014)
Br. J. Pharmacol.
, vol.171
, pp. 2739-2750
-
-
Cheng, P.-W.1
Ho, W.-Y.2
Su, Y.-T.3
Lu, P.-J.4
Chen, B.-Z.5
Cheng, W.-H.6
Lu, W.-H.7
Sun, G.-C.8
Yeh, T.-C.9
Hsiao, M.10
Tseng, C.-J.11
-
23
-
-
84954509048
-
Cerebroprotection of flavanol (-)-epicatechin after traumatic brain injury via Nrf2-dependent and -independent pathways
-
Cheng, T., Wang, W., Li, Q., Han, X., Xing, J., Qi, C., Lan, X., Wan, J., Potts, A., Guan, F., Wang, J., Cerebroprotection of flavanol (-)-epicatechin after traumatic brain injury via Nrf2-dependent and -independent pathways. Free Radic. Biol. Med. 92 (2016), 15–28 https://doi.org/10.1016/j.freeradbiomed.2015.12.027.
-
(2016)
Free Radic. Biol. Med.
, vol.92
, pp. 15-28
-
-
Cheng, T.1
Wang, W.2
Li, Q.3
Han, X.4
Xing, J.5
Qi, C.6
Lan, X.7
Wan, J.8
Potts, A.9
Guan, F.10
Wang, J.11
-
24
-
-
84955083741
-
The PI3K/Akt pathway is involved in procyanidin-mediated suppression of human colorectal cancer cell growth
-
Choy, Y.Y., Fraga, M., Mackenzie, G.G., Waterhouse, A.L., Cremonini, E., Oteiza, P.I., The PI3K/Akt pathway is involved in procyanidin-mediated suppression of human colorectal cancer cell growth. Mol. Carcinog. 55 (2016), 2196–2209 https://doi.org/10.1002/mc.22461.
-
(2016)
Mol. Carcinog.
, vol.55
, pp. 2196-2209
-
-
Choy, Y.Y.1
Fraga, M.2
Mackenzie, G.G.3
Waterhouse, A.L.4
Cremonini, E.5
Oteiza, P.I.6
-
25
-
-
0031886669
-
Structure-activity relationship and classification of flavonoids as inhibitors of xanthine oxidase and superoxide scavengers
-
Cos, P., Ying, L., Calomme, M., Hu, J.P., Cimanga, K., Van Poel, B., Pieters, L., Vlietinck, A.J., Vanden Berghe, D., Structure-activity relationship and classification of flavonoids as inhibitors of xanthine oxidase and superoxide scavengers. J. Nat. Prod. 61 (1998), 71–76 https://doi.org/10.1021/np970237h.
-
(1998)
J. Nat. Prod.
, vol.61
, pp. 71-76
-
-
Cos, P.1
Ying, L.2
Calomme, M.3
Hu, J.P.4
Cimanga, K.5
Van Poel, B.6
Pieters, L.7
Vlietinck, A.J.8
Vanden Berghe, D.9
-
26
-
-
84960377761
-
(-)-Epicatechin improves insulin sensitivity in high fat diet-fed mice
-
Cremonini, E., Bettaieb, A., Haj, F.G., Fraga, C.G., Oteiza, P.I., (-)-Epicatechin improves insulin sensitivity in high fat diet-fed mice. Arch. Biochem. Biophys. 599 (2016), 13–21 https://doi.org/10.1016/j.abb.2016.03.006.
-
(2016)
Arch. Biochem. Biophys.
, vol.599
, pp. 13-21
-
-
Cremonini, E.1
Bettaieb, A.2
Haj, F.G.3
Fraga, C.G.4
Oteiza, P.I.5
-
27
-
-
85034034558
-
(-)-Epicatechin protects the intestinal barrier from high fat diet-induced permeabilization: implications for steatosis and insulin resistance
-
Cremonini, E., Wang, Z., Bettaieb, A., Adamo, A.M., Daveri, E., Mills, D.A., Kalanetra, K.M., Haj, F.G., Karakas, S., Oteiza, P.I., (-)-Epicatechin protects the intestinal barrier from high fat diet-induced permeabilization: implications for steatosis and insulin resistance. Redox Biol. 14 (2018), 588–599 https://doi.org/10.1016/j.redox.2017.11.002.
-
(2018)
Redox Biol.
, vol.14
, pp. 588-599
-
-
Cremonini, E.1
Wang, Z.2
Bettaieb, A.3
Adamo, A.M.4
Daveri, E.5
Mills, D.A.6
Kalanetra, K.M.7
Haj, F.G.8
Karakas, S.9
Oteiza, P.I.10
-
28
-
-
78649631235
-
Bioavailability of dietary flavonoids and phenolic compounds
-
Crozier, A., Del Rio, D., Clifford, M.N., Bioavailability of dietary flavonoids and phenolic compounds. Mol. Aspect. Med. 31 (2010), 446–467 https://doi.org/10.1016/j.mam.2010.09.007.
-
(2010)
Mol. Aspect. Med.
, vol.31
, pp. 446-467
-
-
Crozier, A.1
Del Rio, D.2
Clifford, M.N.3
-
29
-
-
0141752795
-
Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival
-
Cullinan, S.B., Zhang, D., Hannink, M., Arvisais, E., Kaufman, R.J., Diehl, J.A., Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival. Mol. Cell Biol. 23 (2003), 7198–7209.
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 7198-7209
-
-
Cullinan, S.B.1
Zhang, D.2
Hannink, M.3
Arvisais, E.4
Kaufman, R.J.5
Diehl, J.A.6
-
30
-
-
84859080819
-
Chronic ingestion of flavan-3-ols and isoflavones improves insulin sensitivity and lipoprotein status and attenuates estimated 10-year CVD risk in medicated postmenopausal women with type 2 diabetes: a 1-year, double-blind, randomized, controlled trial
-
Curtis, P.J., Sampson, M., Potter, J., Dhatariya, K., Kroon, P.A., Cassidy, A., Chronic ingestion of flavan-3-ols and isoflavones improves insulin sensitivity and lipoprotein status and attenuates estimated 10-year CVD risk in medicated postmenopausal women with type 2 diabetes: a 1-year, double-blind, randomized, controlled trial. Diabetes Care 35 (2012), 226–232 https://doi.org/10.2337/dc11-1443.
-
(2012)
Diabetes Care
, vol.35
, pp. 226-232
-
-
Curtis, P.J.1
Sampson, M.2
Potter, J.3
Dhatariya, K.4
Kroon, P.A.5
Cassidy, A.6
-
31
-
-
84655163461
-
Large procyanidins prevent bile-acid-induced oxidant production and membrane-initiated ERK1/2, p38, and Akt activation in Caco-2 cells
-
Da Silva, M., Jaggers, G.K., Verstraeten, S.V., Erlejman, A.G., Fraga, C.G., Oteiza, P.I., Large procyanidins prevent bile-acid-induced oxidant production and membrane-initiated ERK1/2, p38, and Akt activation in Caco-2 cells. Free Radic. Biol. Med. 52 (2012), 151–159 https://doi.org/10.1016/j.freeradbiomed.2011.10.436.
-
(2012)
Free Radic. Biol. Med.
, vol.52
, pp. 151-159
-
-
Da Silva, M.1
Jaggers, G.K.2
Verstraeten, S.V.3
Erlejman, A.G.4
Fraga, C.G.5
Oteiza, P.I.6
-
32
-
-
54349124273
-
Nrf2-induced antioxidant protection: a promising target to counteract ROS-mediated damage in neurodegenerative disease?
-
de Vries, H.E., Witte, M., Hondius, D., Rozemuller, A.J.M., Drukarch, B., Hoozemans, J., van Horssen, J., Nrf2-induced antioxidant protection: a promising target to counteract ROS-mediated damage in neurodegenerative disease?. Free Radic. Biol. Med. 45 (2008), 1375–1383 https://doi.org/10.1016/j.freeradbiomed.2008.09.001.
-
(2008)
Free Radic. Biol. Med.
, vol.45
, pp. 1375-1383
-
-
de Vries, H.E.1
Witte, M.2
Hondius, D.3
Rozemuller, A.J.M.4
Drukarch, B.5
Hoozemans, J.6
van Horssen, J.7
-
33
-
-
84989851768
-
Flavonoids and naphthoflavonoids: wider roles in the modulation of cytochrome P450 family 1 enzymes
-
Dong, J., Zhang, Q., Cui, Q., Huang, G., Pan, X., Li, S., Flavonoids and naphthoflavonoids: wider roles in the modulation of cytochrome P450 family 1 enzymes. ChemMedChem 11 (2016), 2102–2118 https://doi.org/10.1002/cmdc.201600316.
-
(2016)
ChemMedChem
, vol.11
, pp. 2102-2118
-
-
Dong, J.1
Zhang, Q.2
Cui, Q.3
Huang, G.4
Pan, X.5
Li, S.6
-
34
-
-
17144408313
-
The interaction of flavonoids with mitochondria: effects on energetic processes
-
Dorta, D.J., Pigoso, A.A., Mingatto, F.E., Rodrigues, T., Prado, I.M.R., Helena, A.F.C., Uyemura, S.A., Santos, A.C., Curti, C., The interaction of flavonoids with mitochondria: effects on energetic processes. Chem. Biol. Interact. 152 (2005), 67–78 https://doi.org/10.1016/j.cbi.2005.02.004.
-
(2005)
Chem. Biol. Interact.
, vol.152
, pp. 67-78
-
-
Dorta, D.J.1
Pigoso, A.A.2
Mingatto, F.E.3
Rodrigues, T.4
Prado, I.M.R.5
Helena, A.F.C.6
Uyemura, S.A.7
Santos, A.C.8
Curti, C.9
-
35
-
-
84935509803
-
Supplementation of the pure flavonoids epicatechin and quercetin affects some biomarkers of endothelial dysfunction and inflammation in (pre)hypertensive adults: a randomized double-blind, placebo-controlled, crossover trial
-
Dower, J.I., Geleijnse, J.M., Gijsbers, L., Schalkwijk, C., Kromhout, D., Hollman, P.C., Supplementation of the pure flavonoids epicatechin and quercetin affects some biomarkers of endothelial dysfunction and inflammation in (pre)hypertensive adults: a randomized double-blind, placebo-controlled, crossover trial. J. Nutr. 145 (2015), 1459–1463 https://doi.org/10.3945/jn.115.211888.
-
(2015)
J. Nutr.
, vol.145
, pp. 1459-1463
-
-
Dower, J.I.1
Geleijnse, J.M.2
Gijsbers, L.3
Schalkwijk, C.4
Kromhout, D.5
Hollman, P.C.6
-
36
-
-
33749044156
-
Procyanidins protect Caco-2 cells from bile acid- and oxidant-induced damage
-
Erlejman, A.G., Fraga, C.G., Oteiza, P.I., Procyanidins protect Caco-2 cells from bile acid- and oxidant-induced damage. Free Radic. Biol. Med. 41 (2006), 1247–1256 https://doi.org/10.1016/j.freeradbiomed.2006.07.002.
-
(2006)
Free Radic. Biol. Med.
, vol.41
, pp. 1247-1256
-
-
Erlejman, A.G.1
Fraga, C.G.2
Oteiza, P.I.3
-
37
-
-
48049104552
-
TNFalpha-induced NF-kappaB activation and cell oxidant production are modulated by hexameric procyanidins in Caco-2 cells
-
Erlejman, A.G., Jaggers, G., Fraga, C.G., Oteiza, P.I., TNFalpha-induced NF-kappaB activation and cell oxidant production are modulated by hexameric procyanidins in Caco-2 cells. Arch. Biochem. Biophys. 476 (2008), 186–195 https://doi.org/10.1016/j.abb.2008.01.024.
-
(2008)
Arch. Biochem. Biophys.
, vol.476
, pp. 186-195
-
-
Erlejman, A.G.1
Jaggers, G.2
Fraga, C.G.3
Oteiza, P.I.4
-
38
-
-
11044234344
-
The interaction of flavonoids with membranes: potential determinant of flavonoid antioxidant effects
-
Erlejman, A.G., Verstraeten, S.V., Fraga, C.G., Oteiza, P.I., The interaction of flavonoids with membranes: potential determinant of flavonoid antioxidant effects. Free Radic. Res. 38 (2004), 1311–1320 https://doi.org/10.1080/10715760400016105.
-
(2004)
Free Radic. Res.
, vol.38
, pp. 1311-1320
-
-
Erlejman, A.G.1
Verstraeten, S.V.2
Fraga, C.G.3
Oteiza, P.I.4
-
39
-
-
84892369382
-
How do nutritional antioxidants really work: nucleophilic tone and para-hormesis versus free radical scavenging in vivo
-
Forman, H.J., Davies, K.J.A., Ursini, F., How do nutritional antioxidants really work: nucleophilic tone and para-hormesis versus free radical scavenging in vivo. Free Radic. Biol. Med. 66 (2014), 24–35 https://doi.org/10.1016/j.freeradbiomed.2013.05.045.
-
(2014)
Free Radic. Biol. Med.
, vol.66
, pp. 24-35
-
-
Forman, H.J.1
Davies, K.J.A.2
Ursini, F.3
-
40
-
-
34248572037
-
Plant polyphenols: how to translate their in vitro antioxidant actions to in vivo conditions
-
Fraga, C.G., Plant polyphenols: how to translate their in vitro antioxidant actions to in vivo conditions. IUBMB Life 59 (2007), 308–315 https://doi.org/10.1080/15216540701230529.
-
(2007)
IUBMB Life
, vol.59
, pp. 308-315
-
-
Fraga, C.G.1
-
41
-
-
78649636886
-
Basic biochemical mechanisms behind the health benefits of polyphenols
-
Fraga, C.G., Galleano, M., Verstraeten, S.V., Oteiza, P.I., Basic biochemical mechanisms behind the health benefits of polyphenols. Mol. Aspect. Med. 31 (2010), 435–445 https://doi.org/10.1016/j.mam.2010.09.006.
-
(2010)
Mol. Aspect. Med.
, vol.31
, pp. 435-445
-
-
Fraga, C.G.1
Galleano, M.2
Verstraeten, S.V.3
Oteiza, P.I.4
-
42
-
-
78650740147
-
Cocoa flavanols: effects on vascular nitric oxide and blood pressure
-
Fraga, C.G., Litterio, M.C., Prince, P.D., Calabró V., Piotrkowski, B., Galleano, M., Cocoa flavanols: effects on vascular nitric oxide and blood pressure. J. Clin. Biochem. Nutr. 48 (2011), 63–67 https://doi.org/10.3164/jcbn.11-010FR.
-
(2011)
J. Clin. Biochem. Nutr.
, vol.48
, pp. 63-67
-
-
Fraga, C.G.1
Litterio, M.C.2
Prince, P.D.3
Calabró, V.4
Piotrkowski, B.5
Galleano, M.6
-
43
-
-
79960957271
-
Dietary flavonoids: role of (-)-epicatechin and related procyanidins in cell signaling
-
Fraga, C.G., Oteiza, P.I., Dietary flavonoids: role of (-)-epicatechin and related procyanidins in cell signaling. Free Radic. Biol. Med. 51 (2011), 813–823 https://doi.org/10.1016/j.freeradbiomed.2011.06.002.
-
(2011)
Free Radic. Biol. Med.
, vol.51
, pp. 813-823
-
-
Fraga, C.G.1
Oteiza, P.I.2
-
44
-
-
84890124989
-
In vitro measurements and interpretation of total antioxidant capacity
-
Fraga, C.G., Oteiza, P.I., Galleano, M., In vitro measurements and interpretation of total antioxidant capacity. Biochim. Biophys. Acta 1840 (2014), 931–934 https://doi.org/10.1016/j.bbagen.2013.06.030.
-
(2014)
Biochim. Biophys. Acta
, vol.1840
, pp. 931-934
-
-
Fraga, C.G.1
Oteiza, P.I.2
Galleano, M.3
-
45
-
-
84964057137
-
The effect of increasing fruit and vegetable consumption on overall diet: a systematic review and meta-analysis
-
Fulton, S.L., McKinley, M.C., Young, I.S., Cardwell, C.R., Woodside, J.V., The effect of increasing fruit and vegetable consumption on overall diet: a systematic review and meta-analysis. Crit. Rev. Food Sci. Nutr. 56 (2016), 802–816 https://doi.org/10.1080/10408398.2012.727917.
-
(2016)
Crit. Rev. Food Sci. Nutr.
, vol.56
, pp. 802-816
-
-
Fulton, S.L.1
McKinley, M.C.2
Young, I.S.3
Cardwell, C.R.4
Woodside, J.V.5
-
46
-
-
84890743972
-
(-)-Epicatechin reduces blood pressure and improves vasorelaxation in spontaneously hypertensive rats by NO-mediated mechanism
-
Galleano, M., Bernatova, I., Puzserova, A., Balis, P., Sestakova, N., Pechanova, O., Fraga, C.G., (-)-Epicatechin reduces blood pressure and improves vasorelaxation in spontaneously hypertensive rats by NO-mediated mechanism. IUBMB Life 65 (2013), 710–715 https://doi.org/10.1002/iub.1185.
-
(2013)
IUBMB Life
, vol.65
, pp. 710-715
-
-
Galleano, M.1
Bernatova, I.2
Puzserova, A.3
Balis, P.4
Sestakova, N.5
Pechanova, O.6
Fraga, C.G.7
-
47
-
-
78650735365
-
Hypertension, nitric oxide, oxidants, and dietary plant polyphenols
-
Galleano, M., Pechanova, O., Fraga, C.G., Hypertension, nitric oxide, oxidants, and dietary plant polyphenols. Curr. Pharmaceut. Biotechnol. 11 (2010), 837–848.
-
(2010)
Curr. Pharmaceut. Biotechnol.
, vol.11
, pp. 837-848
-
-
Galleano, M.1
Pechanova, O.2
Fraga, C.G.3
-
48
-
-
77956179560
-
Antioxidant actions of flavonoids: thermodynamic and kinetic analysis
-
Galleano, M., Verstraeten, S.V., Oteiza, P.I., Fraga, C.G., Antioxidant actions of flavonoids: thermodynamic and kinetic analysis. Arch. Biochem. Biophys. 501 (2010), 23–30 https://doi.org/10.1016/j.abb.2010.04.005.
-
(2010)
Arch. Biochem. Biophys.
, vol.501
, pp. 23-30
-
-
Galleano, M.1
Verstraeten, S.V.2
Oteiza, P.I.3
Fraga, C.G.4
-
49
-
-
84906790006
-
Consumption of both low and high (-)-epicatechin apple puree attenuates platelet reactivity and increases plasma concentrations of nitric oxide metabolites: a randomized controlled trial
-
Gasper, A., Hollands, W., Casgrain, A., Saha, S., Teucher, B., Dainty, J.R., Venema, D.P., Hollman, P.C., Rein, M.J., Nelson, R., Williamson, G., Kroon, P.A., Consumption of both low and high (-)-epicatechin apple puree attenuates platelet reactivity and increases plasma concentrations of nitric oxide metabolites: a randomized controlled trial. Arch. Biochem. Biophys. 559 (2014), 29–37 https://doi.org/10.1016/j.abb.2014.05.026.
-
(2014)
Arch. Biochem. Biophys.
, vol.559
, pp. 29-37
-
-
Gasper, A.1
Hollands, W.2
Casgrain, A.3
Saha, S.4
Teucher, B.5
Dainty, J.R.6
Venema, D.P.7
Hollman, P.C.8
Rein, M.J.9
Nelson, R.10
Williamson, G.11
Kroon, P.A.12
-
50
-
-
84929085559
-
The cysteine proteome
-
Go, Y.-M., Chandler, J.D., Jones, D.P., The cysteine proteome. Free Radic. Biol. Med. 84 (2015), 227–245 https://doi.org/10.1016/j.freeradbiomed.2015.03.022.
-
(2015)
Free Radic. Biol. Med.
, vol.84
, pp. 227-245
-
-
Go, Y.-M.1
Chandler, J.D.2
Jones, D.P.3
-
51
-
-
80055058069
-
Chronic (-)-epicatechin improves vascular oxidative and inflammatory status but not hypertension in chronic nitric oxide-deficient rats
-
Gómez-Guzmán, M., Jiménez, R., Sánchez, M., Romero, M., O'Valle, F., Lopez-Sepulveda, R., Quintela, A.M., Galindo, P., Zarzuelo, M.J., Bailón, E., Delpón, E., Perez-Vizcaino, F., Duarte, J., Chronic (-)-epicatechin improves vascular oxidative and inflammatory status but not hypertension in chronic nitric oxide-deficient rats. Br. J. Nutr. 106 (2011), 1337–1348 https://doi.org/10.1017/S0007114511004314.
-
(2011)
Br. J. Nutr.
, vol.106
, pp. 1337-1348
-
-
Gómez-Guzmán, M.1
Jiménez, R.2
Sánchez, M.3
Romero, M.4
O'Valle, F.5
Lopez-Sepulveda, R.6
Quintela, A.M.7
Galindo, P.8
Zarzuelo, M.J.9
Bailón, E.10
Delpón, E.11
Perez-Vizcaino, F.12
Duarte, J.13
-
52
-
-
84655165055
-
Epicatechin lowers blood pressure, restores endothelial function, and decreases oxidative stress and endothelin-1 and NADPH oxidase activity in DOCA-salt hypertension
-
Gómez-Guzmán, M., Jiménez, R., Sánchez, M., Zarzuelo, M.J., Galindo, P., Quintela, A.M., López-Sepúlveda, R., Romero, M., Tamargo, J., Vargas, F., Pérez-Vizcaíno, F., Duarte, J., Epicatechin lowers blood pressure, restores endothelial function, and decreases oxidative stress and endothelin-1 and NADPH oxidase activity in DOCA-salt hypertension. Free Radic. Biol. Med. 52 (2012), 70–79 https://doi.org/10.1016/j.freeradbiomed.2011.09.015.
-
(2012)
Free Radic. Biol. Med.
, vol.52
, pp. 70-79
-
-
Gómez-Guzmán, M.1
Jiménez, R.2
Sánchez, M.3
Zarzuelo, M.J.4
Galindo, P.5
Quintela, A.M.6
López-Sepúlveda, R.7
Romero, M.8
Tamargo, J.9
Vargas, F.10
Pérez-Vizcaíno, F.11
Duarte, J.12
-
53
-
-
75549090203
-
Epicatechin induces NF-kappaB, activator protein-1 (AP-1) and nuclear transcription factor erythroid 2p45-related factor-2 (Nrf2) via phosphatidylinositol-3-kinase/protein kinase B (PI3K/AKT) and extracellular regulated kinase (ERK) signalling in HepG2 cells
-
Granado-Serrano, A.B., Martín, M.A., Haegeman, G., Goya, L., Bravo, L., Ramos, S., Epicatechin induces NF-kappaB, activator protein-1 (AP-1) and nuclear transcription factor erythroid 2p45-related factor-2 (Nrf2) via phosphatidylinositol-3-kinase/protein kinase B (PI3K/AKT) and extracellular regulated kinase (ERK) signalling in HepG2 cells. Br. J. Nutr. 103 (2010), 168–179 https://doi.org/10.1017/S0007114509991747.
-
(2010)
Br. J. Nutr.
, vol.103
, pp. 168-179
-
-
Granado-Serrano, A.B.1
Martín, M.A.2
Haegeman, G.3
Goya, L.4
Bravo, L.5
Ramos, S.6
-
54
-
-
84927611320
-
The role of p38 MAPK in the induction of intestinal inflammation by dietary oxysterols: modulation by wine phenolics
-
Guina, T., Deiana, M., Calfapietra, S., Cabboi, B., Maina, M., Tuberoso, C.I., Leonarduzzi, G., Gamba, P., Gargiulo, S., Testa, G., Poli, G., Biasi, F., The role of p38 MAPK in the induction of intestinal inflammation by dietary oxysterols: modulation by wine phenolics. Food Funct. 6 (2015), 1218–1228 https://doi.org/10.1039/C4FO01116C.
-
(2015)
Food Funct.
, vol.6
, pp. 1218-1228
-
-
Guina, T.1
Deiana, M.2
Calfapietra, S.3
Cabboi, B.4
Maina, M.5
Tuberoso, C.I.6
Leonarduzzi, G.7
Gamba, P.8
Gargiulo, S.9
Testa, G.10
Poli, G.11
Biasi, F.12
-
55
-
-
0037105296
-
Structure and function of xanthine oxidoreductase: where are we now?
-
Harrison, R., Structure and function of xanthine oxidoreductase: where are we now?. Free Radic. Biol. Med. 33 (2002), 774–797.
-
(2002)
Free Radic. Biol. Med.
, vol.33
, pp. 774-797
-
-
Harrison, R.1
-
56
-
-
84885122596
-
Increased consumption of fruit and vegetables for the primary prevention of cardiovascular diseases
-
CD009874
-
Hartley, L., Igbinedion, E., Holmes, J., Flowers, N., Thorogood, M., Clarke, A., Stranges, S., Hooper, L., Rees, K., Increased consumption of fruit and vegetables for the primary prevention of cardiovascular diseases. Cochrane Database Syst. Rev., 2013 CD009874 https://doi.org/10.1002/14651858.CD009874.pub2.
-
(2013)
Cochrane Database Syst. Rev.
-
-
Hartley, L.1
Igbinedion, E.2
Holmes, J.3
Flowers, N.4
Thorogood, M.5
Clarke, A.6
Stranges, S.7
Hooper, L.8
Rees, K.9
-
57
-
-
84880268679
-
Biological nitric oxide signalling: chemistry and terminology
-
Heinrich, T.A., da Silva, R.S., Miranda, K.M., Switzer, C.H., Wink, D.A., Fukuto, J.M., Biological nitric oxide signalling: chemistry and terminology. Br. J. Pharmacol. 169 (2013), 1417–1429 https://doi.org/10.1111/bph.12217.
-
(2013)
Br. J. Pharmacol.
, vol.169
, pp. 1417-1429
-
-
Heinrich, T.A.1
da Silva, R.S.2
Miranda, K.M.3
Switzer, C.H.4
Wink, D.A.5
Fukuto, J.M.6
-
58
-
-
68849121542
-
Aspects of antioxidant foods and supplements in health and disease
-
Herrera, E., Jiménez, R., Aruoma, O.I., Hercberg, S., Sánchez-García, I., Fraga, C., Aspects of antioxidant foods and supplements in health and disease. Nutr. Rev. 67 (2009), S140–S144 https://doi.org/10.1111/j.1753-4887.2009.00177.x.
-
(2009)
Nutr. Rev.
, vol.67
, pp. S140-S144
-
-
Herrera, E.1
Jiménez, R.2
Aruoma, O.I.3
Hercberg, S.4
Sánchez-García, I.5
Fraga, C.6
-
59
-
-
0027504187
-
Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study
-
Hertog, M.G., Feskens, E.J., Hollman, P.C., Katan, M.B., Kromhout, D., Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study. Lancet 342 (1993), 1007–1011.
-
(1993)
Lancet
, vol.342
, pp. 1007-1011
-
-
Hertog, M.G.1
Feskens, E.J.2
Hollman, P.C.3
Katan, M.B.4
Kromhout, D.5
-
60
-
-
0036784053
-
Procyanidin dimer B2 [epicatechin-(4beta-8)-epicatechin] in human plasma after the consumption of a flavanol-rich cocoa
-
Holt, R.R., Lazarus, S.A., Sullards, M.C., Zhu, Q.Y., Schramm, D.D., Hammerstone, J.F., Fraga, C.G., Schmitz, H.H., Keen, C.L., Procyanidin dimer B2 [epicatechin-(4beta-8)-epicatechin] in human plasma after the consumption of a flavanol-rich cocoa. Am. J. Clin. Nutr. 76 (2002), 798–804.
-
(2002)
Am. J. Clin. Nutr.
, vol.76
, pp. 798-804
-
-
Holt, R.R.1
Lazarus, S.A.2
Sullards, M.C.3
Zhu, Q.Y.4
Schramm, D.D.5
Hammerstone, J.F.6
Fraga, C.G.7
Schmitz, H.H.8
Keen, C.L.9
-
61
-
-
46649098436
-
Flavonoids, flavonoid-rich foods, and cardiovascular risk: a meta-analysis of randomized controlled trials
-
Hooper, L., Kroon, P.A., Rimm, E.B., Cohn, J.S., Harvey, I., Le Cornu, K.A., Ryder, J.J., Hall, W.L., Cassidy, A., Flavonoids, flavonoid-rich foods, and cardiovascular risk: a meta-analysis of randomized controlled trials. Am. J. Clin. Nutr. 88 (2008), 38–50.
-
(2008)
Am. J. Clin. Nutr.
, vol.88
, pp. 38-50
-
-
Hooper, L.1
Kroon, P.A.2
Rimm, E.B.3
Cohn, J.S.4
Harvey, I.5
Le Cornu, K.A.6
Ryder, J.J.7
Hall, W.L.8
Cassidy, A.9
-
62
-
-
84956697082
-
Sulforaphane and other nutrigenomic Nrf2 activators: can the Clinician's expectation be matched by the reality?
-
Houghton, C.A., Fassett, R.G., Coombes, J.S., Sulforaphane and other nutrigenomic Nrf2 activators: can the Clinician's expectation be matched by the reality?. Oxid. Med. Cell. Longev, 2016, 2016, 7857186 https://doi.org/10.1155/2016/7857186.
-
(2016)
Oxid. Med. Cell. Longev
, vol.2016
, pp. 7857186
-
-
Houghton, C.A.1
Fassett, R.G.2
Coombes, J.S.3
-
63
-
-
84983150554
-
The complexity of the Nrf2 pathway: beyond the antioxidant response
-
Huang, Y., Li, W., Su, Z., Kong, A.-N.T., The complexity of the Nrf2 pathway: beyond the antioxidant response. J. Nutr. Biochem. 26 (2015), 1401–1413 https://doi.org/10.1016/j.jnutbio.2015.08.001.
-
(2015)
J. Nutr. Biochem.
, vol.26
, pp. 1401-1413
-
-
Huang, Y.1
Li, W.2
Su, Z.3
Kong, A.-N.T.4
-
64
-
-
84860912859
-
(-)-Epicatechin maintains endurance training adaptation in mice after 14 days of detraining
-
Hüttemann, M., Lee, I., Malek, M.H., (-)-Epicatechin maintains endurance training adaptation in mice after 14 days of detraining. Faseb. J. 26 (2012), 1413–1422 https://doi.org/10.1096/fj.11-196154.
-
(2012)
Faseb. J.
, vol.26
, pp. 1413-1422
-
-
Hüttemann, M.1
Lee, I.2
Malek, M.H.3
-
65
-
-
84874684795
-
(-)-Epicatechin is associated with increased angiogenic and mitochondrial signalling in the hindlimb of rats selectively bred for innate low running capacity
-
Hüttemann, M., Lee, I., Perkins, G.A., Britton, S.L., Koch, L.G., Malek, M.H., (-)-Epicatechin is associated with increased angiogenic and mitochondrial signalling in the hindlimb of rats selectively bred for innate low running capacity. Clin. Sci. London 124 (2013), 663–674 https://doi.org/10.1042/CS20120469.
-
(2013)
Clin. Sci. London
, vol.124
, pp. 663-674
-
-
Hüttemann, M.1
Lee, I.2
Perkins, G.A.3
Britton, S.L.4
Koch, L.G.5
Malek, M.H.6
-
66
-
-
0033862093
-
Effects of cocoa extracts on endothelium-dependent relaxation
-
Karim, M., McCormick, K., Kappagoda, C.T., Effects of cocoa extracts on endothelium-dependent relaxation. J. Nutr. 130 (2000), 2105S–2108S.
-
(2000)
J. Nutr.
, vol.130
, pp. 2105S-2108S
-
-
Karim, M.1
McCormick, K.2
Kappagoda, C.T.3
-
67
-
-
4644237615
-
Inhibitory effects of epicatechin on interleukin-1beta-induced inducible nitric oxide synthase expression in RINm5F cells and rat pancreatic islets by down-regulation of NF-kappaB activation
-
Kim, M.-J., Ryu, G.R., Kang, J.-H., Sim, S.S., Min, D.S., Rhie, D.-J., Yoon, S.H., Hahn, S.J., Jeong, I.-K., Hong, K.-J., Kim, M.-S., Jo, Y.-H., Inhibitory effects of epicatechin on interleukin-1beta-induced inducible nitric oxide synthase expression in RINm5F cells and rat pancreatic islets by down-regulation of NF-kappaB activation. Biochem. Pharmacol. 68 (2004), 1775–1785 https://doi.org/10.1016/j.bcp.2004.06.031.
-
(2004)
Biochem. Pharmacol.
, vol.68
, pp. 1775-1785
-
-
Kim, M.-J.1
Ryu, G.R.2
Kang, J.-H.3
Sim, S.S.4
Min, D.S.5
Rhie, D.-J.6
Yoon, S.H.7
Hahn, S.J.8
Jeong, I.-K.9
Hong, K.-J.10
Kim, M.-S.11
Jo, Y.-H.12
-
68
-
-
84996992938
-
(-)-Epicatechin prevents blood pressure increase and reduces locomotor hyperactivity in young spontaneously hypertensive rats
-
Kluknavsky, M., Balis, P., Puzserova, A., Radosinska, J., Berenyiova, A., Drobna, M., Lukac, S., Muchova, J., Bernatova, I., (-)-Epicatechin prevents blood pressure increase and reduces locomotor hyperactivity in young spontaneously hypertensive rats. Oxid. Med. Cell. Longev, 2016, 2016, 6949020 https://doi.org/10.1155/2016/6949020.
-
(2016)
Oxid. Med. Cell. Longev
, vol.2016
, pp. 6949020
-
-
Kluknavsky, M.1
Balis, P.2
Puzserova, A.3
Radosinska, J.4
Berenyiova, A.5
Drobna, M.6
Lukac, S.7
Muchova, J.8
Bernatova, I.9
-
69
-
-
0028349156
-
Nitric oxide synthases in mammals
-
Knowles, R.G., Moncada, S., Nitric oxide synthases in mammals. Biochem. J. 298 (1994), 249–258.
-
(1994)
Biochem. J.
, vol.298
, pp. 249-258
-
-
Knowles, R.G.1
Moncada, S.2
-
70
-
-
81155128482
-
Complex I and cytochrome c are molecular targets of flavonoids that inhibit hydrogen peroxide production by mitochondria
-
Lagoa, R., Graziani, I., Lopez-Sanchez, C., Garcia-Martinez, V., Gutierrez-Merino, C., Complex I and cytochrome c are molecular targets of flavonoids that inhibit hydrogen peroxide production by mitochondria. Biochim. Biophys. Acta 1807 (2011), 1562–1572 https://doi.org/10.1016/j.bbabio.2011.09.022.
-
(2011)
Biochim. Biophys. Acta
, vol.1807
, pp. 1562-1572
-
-
Lagoa, R.1
Graziani, I.2
Lopez-Sanchez, C.3
Garcia-Martinez, V.4
Gutierrez-Merino, C.5
-
71
-
-
84926467838
-
(-)-Epicatechin combined with 8 weeks of treadmill exercise is associated with increased angiogenic and mitochondrial signaling in mice
-
Lee, I., Hüttemann, M., Kruger, A., Bollig-Fischer, A., Malek, M.H., (-)-Epicatechin combined with 8 weeks of treadmill exercise is associated with increased angiogenic and mitochondrial signaling in mice. Front. Pharmacol., 6, 2015, 43 https://doi.org/10.3389/fphar.2015.00043.
-
(2015)
Front. Pharmacol.
, vol.6
, pp. 43
-
-
Lee, I.1
Hüttemann, M.2
Kruger, A.3
Bollig-Fischer, A.4
Malek, M.H.5
-
72
-
-
84953888562
-
(-)-Epicatechin attenuates degradation of mouse oxidative muscle following hindlimb suspension
-
Lee, I., Hüttemann, M., Malek, M.H., (-)-Epicatechin attenuates degradation of mouse oxidative muscle following hindlimb suspension. J. Strength Condit Res. 30 (2016), 1–10 https://doi.org/10.1519/JSC.0000000000001205.
-
(2016)
J. Strength Condit Res.
, vol.30
, pp. 1-10
-
-
Lee, I.1
Hüttemann, M.2
Malek, M.H.3
-
73
-
-
84897051682
-
Oral administration of the flavanol (-)-epicatechin bolsters endogenous protection against focal ischemia through the Nrf2 cytoprotective pathway
-
Leonardo, C.C., Agrawal, M., Singh, N., Moore, J.R., Biswal, S., Doré S., Oral administration of the flavanol (-)-epicatechin bolsters endogenous protection against focal ischemia through the Nrf2 cytoprotective pathway. Eur. J. Neurosci. 38 (2013), 3659–3668 https://doi.org/10.1111/ejn.12362.
-
(2013)
Eur. J. Neurosci.
, vol.38
, pp. 3659-3668
-
-
Leonardo, C.C.1
Agrawal, M.2
Singh, N.3
Moore, J.R.4
Biswal, S.5
Doré, S.6
-
74
-
-
84937397854
-
Efficacy of prophylactic flavan-3-ol in permanent focal ischemia in 12-mo-old mice
-
Leonardo, C.C., Mendes, M., Ahmad, A.S., Doré S., Efficacy of prophylactic flavan-3-ol in permanent focal ischemia in 12-mo-old mice. Am. J. Physiol. Heart Circ. Physiol. 308 (2015), H583–H591 https://doi.org/10.1152/ajpheart.00239.2014.
-
(2015)
Am. J. Physiol. Heart Circ. Physiol.
, vol.308
, pp. H583-H591
-
-
Leonardo, C.C.1
Mendes, M.2
Ahmad, A.S.3
Doré, S.4
-
75
-
-
78650105442
-
NADPH oxidase links endoplasmic reticulum stress, oxidative stress, and PKR activation to induce apoptosis
-
Li, G., Scull, C., Ozcan, L., Tabas, I., NADPH oxidase links endoplasmic reticulum stress, oxidative stress, and PKR activation to induce apoptosis. J. Cell Biol. 191 (2010), 1113–1125 https://doi.org/10.1083/jcb.201006121.
-
(2010)
J. Cell Biol.
, vol.191
, pp. 1113-1125
-
-
Li, G.1
Scull, C.2
Ozcan, L.3
Tabas, I.4
-
76
-
-
84867369706
-
Blood pressure-lowering effect of dietary (-)-epicatechin administration in L-NAME-treated rats is associated with restored nitric oxide levels
-
Litterio, M.C., Jaggers, G., Sagdicoglu Celep, G., Adamo, A.M., Costa, M.A., Oteiza, P.I., Fraga, C.G., Galleano, M., Blood pressure-lowering effect of dietary (-)-epicatechin administration in L-NAME-treated rats is associated with restored nitric oxide levels. Free Radic. Biol. Med. 53 (2012), 1894–1902 https://doi.org/10.1016/j.freeradbiomed.2012.08.585.
-
(2012)
Free Radic. Biol. Med.
, vol.53
, pp. 1894-1902
-
-
Litterio, M.C.1
Jaggers, G.2
Sagdicoglu Celep, G.3
Adamo, A.M.4
Costa, M.A.5
Oteiza, P.I.6
Fraga, C.G.7
Galleano, M.8
-
77
-
-
84942983825
-
(-)-Epicatechin reduces blood pressure increase in high-fructose-fed rats: effects on the determinants of nitric oxide bioavailability
-
Litterio, M.C., Vazquez Prieto, M.A., Adamo, A.M., Elesgaray, R., Oteiza, P.I., Galleano, M., Fraga, C.G., (-)-Epicatechin reduces blood pressure increase in high-fructose-fed rats: effects on the determinants of nitric oxide bioavailability. J. Nutr. Biochem. 26 (2015), 745–751 https://doi.org/10.1016/j.jnutbio.2015.02.004.
-
(2015)
J. Nutr. Biochem.
, vol.26
, pp. 745-751
-
-
Litterio, M.C.1
Vazquez Prieto, M.A.2
Adamo, A.M.3
Elesgaray, R.4
Oteiza, P.I.5
Galleano, M.6
Fraga, C.G.7
-
78
-
-
84891035918
-
Health-promoting components of fruits and vegetables in the diet
-
Liu, R.H., Health-promoting components of fruits and vegetables in the diet. Adv. Nutr. 4 (2013), 384S–392S https://doi.org/10.3945/an.112.003517.
-
(2013)
Adv. Nutr.
, vol.4
, pp. 384S-392S
-
-
Liu, R.H.1
-
79
-
-
84894248052
-
Exploring the benefits and challenges of establishing a DRI-like process for bioactives
-
Lupton, J.R., Atkinson, S.A., Chang, N., Fraga, C.G., Levy, J., Messina, M., Richardson, D.P., van Ommen, B., Yang, Y., Griffiths, J.C., Hathcock, J., Exploring the benefits and challenges of establishing a DRI-like process for bioactives. Eur. J. Nutr. 53:Suppl. l (2014), 1–9 https://doi.org/10.1007/s00394-014-0666-3.
-
(2014)
Eur. J. Nutr.
, vol.53
, pp. 1-9
-
-
Lupton, J.R.1
Atkinson, S.A.2
Chang, N.3
Fraga, C.G.4
Levy, J.5
Messina, M.6
Richardson, D.P.7
van Ommen, B.8
Yang, Y.9
Griffiths, J.C.10
Hathcock, J.11
-
80
-
-
40649105973
-
Dimeric procyanidin B2 inhibits constitutively active NF-kappaB in Hodgkin's lymphoma cells independently of the presence of IkappaB mutations
-
Mackenzie, G.G., Adamo, A.M., Decker, N.P., Oteiza, P.I., Dimeric procyanidin B2 inhibits constitutively active NF-kappaB in Hodgkin's lymphoma cells independently of the presence of IkappaB mutations. Biochem. Pharmacol. 75 (2008), 1461–1471 https://doi.org/10.1016/j.bcp.2007.12.013.
-
(2008)
Biochem. Pharmacol.
, vol.75
, pp. 1461-1471
-
-
Mackenzie, G.G.1
Adamo, A.M.2
Decker, N.P.3
Oteiza, P.I.4
-
81
-
-
1342268337
-
Epicatechin, catechin, and dimeric procyanidins inhibit PMA-induced NF-kappaB activation at multiple steps in Jurkat T cells
-
Mackenzie, G.G., Carrasquedo, F., Delfino, J.M., Keen, C.L., Fraga, C.G., Oteiza, P.I., Epicatechin, catechin, and dimeric procyanidins inhibit PMA-induced NF-kappaB activation at multiple steps in Jurkat T cells. Faseb. J. 18 (2004), 167–169 https://doi.org/10.1096/fj.03-0402fje.
-
(2004)
Faseb. J.
, vol.18
, pp. 167-169
-
-
Mackenzie, G.G.1
Carrasquedo, F.2
Delfino, J.M.3
Keen, C.L.4
Fraga, C.G.5
Oteiza, P.I.6
-
82
-
-
70249118880
-
Dimeric procyanidins are inhibitors of NF-kappaB-DNA binding
-
Mackenzie, G.G., Delfino, J.M., Keen, C.L., Fraga, C.G., Oteiza, P.I., Dimeric procyanidins are inhibitors of NF-kappaB-DNA binding. Biochem. Pharmacol. 78 (2009), 1252–1262 https://doi.org/10.1016/j.bcp.2009.06.111.
-
(2009)
Biochem. Pharmacol.
, vol.78
, pp. 1252-1262
-
-
Mackenzie, G.G.1
Delfino, J.M.2
Keen, C.L.3
Fraga, C.G.4
Oteiza, P.I.5
-
83
-
-
77953476933
-
Transcriptional regulation of NADPH oxidase isoforms, Nox1 and Nox4, by nuclear factor-kappaB in human aortic smooth muscle cells
-
Manea, A., Tanase, L.I., Raicu, M., Simionescu, M., Transcriptional regulation of NADPH oxidase isoforms, Nox1 and Nox4, by nuclear factor-kappaB in human aortic smooth muscle cells. Biochem. Biophys. Res. Commun. 396 (2010), 901–907 https://doi.org/10.1016/j.bbrc.2010.05.019.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.396
, pp. 901-907
-
-
Manea, A.1
Tanase, L.I.2
Raicu, M.3
Simionescu, M.4
-
84
-
-
0014691242
-
Superoxide dismutase. an enzymic function for erythrocuprein (hemocuprein)
-
McCord, J.M., Fridovich, I., Superoxide dismutase. an enzymic function for erythrocuprein (hemocuprein). J. Biol. Chem. 244 (1969), 6049–6055.
-
(1969)
J. Biol. Chem.
, vol.244
, pp. 6049-6055
-
-
McCord, J.M.1
Fridovich, I.2
-
85
-
-
84856370253
-
Flavonoid intake and cardiovascular disease mortality in a prospective cohort of US adults
-
McCullough, M.L., Peterson, J.J., Patel, R., Jacques, P.F., Shah, R., Dwyer, J.T., Flavonoid intake and cardiovascular disease mortality in a prospective cohort of US adults. Am. J. Clin. Nutr. 95 (2012), 454–464 https://doi.org/10.3945/ajcn.111.016634.
-
(2012)
Am. J. Clin. Nutr.
, vol.95
, pp. 454-464
-
-
McCullough, M.L.1
Peterson, J.J.2
Patel, R.3
Jacques, P.F.4
Shah, R.5
Dwyer, J.T.6
-
86
-
-
0033026122
-
Bioflavonoid effects on the mitochondrial respiratory electron transport chain and cytochrome c redox state
-
Moini, H., Arroyo, A., Vaya, J., Packer, L., Bioflavonoid effects on the mitochondrial respiratory electron transport chain and cytochrome c redox state. Redox Rep. 4 (1999), 35–41 https://doi.org/10.1179/135100099101534729.
-
(1999)
Redox Rep.
, vol.4
, pp. 35-41
-
-
Moini, H.1
Arroyo, A.2
Vaya, J.3
Packer, L.4
-
87
-
-
84879689589
-
Effects of (-)-epicatechin and derivatives on nitric oxide mediated induction of mitochondrial proteins
-
Moreno-Ulloa, A., Cid, A., Rubio-Gayosso, I., Ceballos, G., Villarreal, F., Ramirez-Sanchez, I., Effects of (-)-epicatechin and derivatives on nitric oxide mediated induction of mitochondrial proteins. Bioorg. Med. Chem. Lett 23 (2013), 4441–4446 https://doi.org/10.1016/j.bmcl.2013.05.079.
-
(2013)
Bioorg. Med. Chem. Lett
, vol.23
, pp. 4441-4446
-
-
Moreno-Ulloa, A.1
Cid, A.2
Rubio-Gayosso, I.3
Ceballos, G.4
Villarreal, F.5
Ramirez-Sanchez, I.6
-
88
-
-
84941128004
-
The effects of (-)-epicatechin on endothelial cells involve the G protein-coupled estrogen receptor (GPER)
-
Moreno-Ulloa, A., Mendez-Luna, D., Beltran-Partida, E., Castillo, C., Guevara, G., Ramirez-Sanchez, I., Correa-Basurto, J., Ceballos, G., Villarreal, F., The effects of (-)-epicatechin on endothelial cells involve the G protein-coupled estrogen receptor (GPER). Pharmacol. Res. 100 (2015), 309–320 https://doi.org/10.1016/j.phrs.2015.08.014.
-
(2015)
Pharmacol. Res.
, vol.100
, pp. 309-320
-
-
Moreno-Ulloa, A.1
Mendez-Luna, D.2
Beltran-Partida, E.3
Castillo, C.4
Guevara, G.5
Ramirez-Sanchez, I.6
Correa-Basurto, J.7
Ceballos, G.8
Villarreal, F.9
-
89
-
-
84900793436
-
Cell membrane mediated (-)-epicatechin effects on upstream endothelial cell signaling: evidence for a surface receptor
-
Moreno-Ulloa, A., Romero-Perez, D., Villarreal, F., Ceballos, G., Ramirez-Sanchez, I., Cell membrane mediated (-)-epicatechin effects on upstream endothelial cell signaling: evidence for a surface receptor. Bioorg. Med. Chem. Lett 24 (2014), 2749–2752 https://doi.org/10.1016/j.bmcl.2014.04.038.
-
(2014)
Bioorg. Med. Chem. Lett
, vol.24
, pp. 2749-2752
-
-
Moreno-Ulloa, A.1
Romero-Perez, D.2
Villarreal, F.3
Ceballos, G.4
Ramirez-Sanchez, I.5
-
90
-
-
0035828180
-
Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450
-
Muto, S., Fujita, K., Yamazaki, Y., Kamataki, T., Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450. Mutat. Res. 479 (2001), 197–206.
-
(2001)
Mutat. Res.
, vol.479
, pp. 197-206
-
-
Muto, S.1
Fujita, K.2
Yamazaki, Y.3
Kamataki, T.4
-
91
-
-
0033202439
-
Inhibition of xanthine oxidase by flavonoids
-
Nagao, A., Seki, M., Kobayashi, H., Inhibition of xanthine oxidase by flavonoids. Biosci. Biotechnol. Biochem. 63 (1999), 1787–1790.
-
(1999)
Biosci. Biotechnol. Biochem.
, vol.63
, pp. 1787-1790
-
-
Nagao, A.1
Seki, M.2
Kobayashi, H.3
-
92
-
-
84884556412
-
Bidirectional regulation of NF-κB by reactive oxygen species: a role of unfolded protein response
-
Nakajima, S., Kitamura, M., Bidirectional regulation of NF-κB by reactive oxygen species: a role of unfolded protein response. Free Radic. Biol. Med. 65 (2013), 162–174 https://doi.org/10.1016/j.freeradbiomed.2013.06.020.
-
(2013)
Free Radic. Biol. Med.
, vol.65
, pp. 162-174
-
-
Nakajima, S.1
Kitamura, M.2
-
93
-
-
0029810902
-
Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B
-
Natarajan, K., Singh, S., Burke, T.R., Grunberger, D., Aggarwal, B.B., Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B. Proc. Natl. Acad. Sci. U. S. A 93 (1996), 9090–9095.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A
, vol.93
, pp. 9090-9095
-
-
Natarajan, K.1
Singh, S.2
Burke, T.R.3
Grunberger, D.4
Aggarwal, B.B.5
-
94
-
-
84884172868
-
Angiotensin II, NADPH oxidase, and redox signaling in the vasculature
-
Nguyen Dinh Cat, A., Montezano, A.C., Burger, D., Touyz, R.M., Angiotensin II, NADPH oxidase, and redox signaling in the vasculature. Antioxidants Redox Signal. 19 (2013), 1110–1120 https://doi.org/10.1089/ars.2012.4641.
-
(2013)
Antioxidants Redox Signal.
, vol.19
, pp. 1110-1120
-
-
Nguyen Dinh Cat, A.1
Montezano, A.C.2
Burger, D.3
Touyz, R.M.4
-
95
-
-
0037763721
-
Regulatory mechanisms controlling gene expression mediated by the antioxidant response element
-
Nguyen, T., Sherratt, P.J., Pickett, C.B., Regulatory mechanisms controlling gene expression mediated by the antioxidant response element. Annu. Rev. Pharmacol. Toxicol. 43 (2003), 233–260 https://doi.org/10.1146/annurev.pharmtox.43.100901.140229.
-
(2003)
Annu. Rev. Pharmacol. Toxicol.
, vol.43
, pp. 233-260
-
-
Nguyen, T.1
Sherratt, P.J.2
Pickett, C.B.3
-
96
-
-
84905985979
-
Nox4: a hydrogen peroxide-generating oxygen sensor
-
Nisimoto, Y., Diebold, B.A., Cosentino-Gomes, D., Constentino-Gomes, D., Lambeth, J.D., Nox4: a hydrogen peroxide-generating oxygen sensor. Biochemistry (Mosc.) 53 (2014), 5111–5120 https://doi.org/10.1021/bi500331y.
-
(2014)
Biochemistry (Mosc.)
, vol.53
, pp. 5111-5120
-
-
Nisimoto, Y.1
Diebold, B.A.2
Cosentino-Gomes, D.3
Constentino-Gomes, D.4
Lambeth, J.D.5
-
97
-
-
80052793189
-
(-)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle
-
Nogueira, L., Ramirez-Sanchez, I., Perkins, G.A., Murphy, A., Taub, P.R., Ceballos, G., Villarreal, F.J., Hogan, M.C., Malek, M.H., (-)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle. J. Physiol. 589 (2011), 4615–4631 https://doi.org/10.1113/jphysiol.2011.209924.
-
(2011)
J. Physiol.
, vol.589
, pp. 4615-4631
-
-
Nogueira, L.1
Ramirez-Sanchez, I.2
Perkins, G.A.3
Murphy, A.4
Taub, P.R.5
Ceballos, G.6
Villarreal, F.J.7
Hogan, M.C.8
Malek, M.H.9
-
98
-
-
84918801034
-
Co-administration of the flavanol (-)-epicatechin with doxycycline synergistically reduces infarct size in a model of ischemia reperfusion injury by inhibition of mitochondrial swelling
-
Ortiz-Vilchis, P., Yamazaki, K.G., Rubio-Gayosso, I., Ramirez-Sanchez, I., Calzada, C., Romero-Perez, D., Ortiz, A., Meaney, E., Taub, P., Villarreal, F., Ceballos, G., Co-administration of the flavanol (-)-epicatechin with doxycycline synergistically reduces infarct size in a model of ischemia reperfusion injury by inhibition of mitochondrial swelling. Eur. J. Pharmacol. 744 (2014), 76–82 https://doi.org/10.1016/j.ejphar.2014.09.042.
-
(2014)
Eur. J. Pharmacol.
, vol.744
, pp. 76-82
-
-
Ortiz-Vilchis, P.1
Yamazaki, K.G.2
Rubio-Gayosso, I.3
Ramirez-Sanchez, I.4
Calzada, C.5
Romero-Perez, D.6
Ortiz, A.7
Meaney, E.8
Taub, P.9
Villarreal, F.10
Ceballos, G.11
-
99
-
-
18444383384
-
Flavonoid-membrane interactions: a protective role of flavonoids at the membrane surface?
-
Oteiza, P.I., Erlejman, A.G., Verstraeten, S.V., Keen, C.L., Fraga, C.G., Flavonoid-membrane interactions: a protective role of flavonoids at the membrane surface?. Clin. Dev. Immunol. 12 (2005), 19–25.
-
(2005)
Clin. Dev. Immunol.
, vol.12
, pp. 19-25
-
-
Oteiza, P.I.1
Erlejman, A.G.2
Verstraeten, S.V.3
Keen, C.L.4
Fraga, C.G.5
-
100
-
-
85040443288
-
Flavonoids and the gastrointestinal tract: local and systemic effects
-
Oteiza, P.I., Fraga, C.G., Mills, D.A., Taft, D.H., Flavonoids and the gastrointestinal tract: local and systemic effects. Mol. Aspect. Med., 2018 https://doi.org/10.1016/j.mam.2018.01.001.
-
(2018)
Mol. Aspect. Med.
-
-
Oteiza, P.I.1
Fraga, C.G.2
Mills, D.A.3
Taft, D.H.4
-
101
-
-
84948807551
-
Safety and efficacy of cocoa flavanol intake in healthy adults: a randomized, controlled, double-masked trial
-
Ottaviani, J.I., Balz, M., Kimball, J., Ensunsa, J.L., Fong, R., Momma, T.Y., Kwik-Uribe, C., Schroeter, H., Keen, C.L., Safety and efficacy of cocoa flavanol intake in healthy adults: a randomized, controlled, double-masked trial. Am. J. Clin. Nutr. 102 (2015), 1425–1435 https://doi.org/10.3945/ajcn.115.116178.
-
(2015)
Am. J. Clin. Nutr.
, vol.102
, pp. 1425-1435
-
-
Ottaviani, J.I.1
Balz, M.2
Kimball, J.3
Ensunsa, J.L.4
Fong, R.5
Momma, T.Y.6
Kwik-Uribe, C.7
Schroeter, H.8
Keen, C.L.9
-
102
-
-
84976897467
-
The metabolome of [2-(14)C](-)-epicatechin in humans: implications for the assessment of efficacy, safety, and mechanisms of action of polyphenolic bioactives
-
Ottaviani, J.I., Borges, G., Momma, T.Y., Spencer, J.P.E., Keen, C.L., Crozier, A., Schroeter, H., The metabolome of [2-(14)C](-)-epicatechin in humans: implications for the assessment of efficacy, safety, and mechanisms of action of polyphenolic bioactives. Sci. Rep., 6, 2016, 29034 https://doi.org/10.1038/srep29034.
-
(2016)
Sci. Rep.
, vol.6
, pp. 29034
-
-
Ottaviani, J.I.1
Borges, G.2
Momma, T.Y.3
Spencer, J.P.E.4
Keen, C.L.5
Crozier, A.6
Schroeter, H.7
-
103
-
-
84878897773
-
Epicatechin regulation of mitochondrial structure and function is opioid receptor dependent
-
Panneerselvam, M., Ali, S.S., Finley, J.C., Kellerhals, S.E., Migita, M.Y., Head, B.P., Patel, P.M., Roth, D.M., Patel, H.H., Epicatechin regulation of mitochondrial structure and function is opioid receptor dependent. Mol. Nutr. Food Res. 57 (2013), 1007–1014 https://doi.org/10.1002/mnfr.201300026.
-
(2013)
Mol. Nutr. Food Res.
, vol.57
, pp. 1007-1014
-
-
Panneerselvam, M.1
Ali, S.S.2
Finley, J.C.3
Kellerhals, S.E.4
Migita, M.Y.5
Head, B.P.6
Patel, P.M.7
Roth, D.M.8
Patel, H.H.9
-
104
-
-
78249257802
-
Dark chocolate receptors: epicatechin-induced cardiac protection is dependent on delta-opioid receptor stimulation
-
Panneerselvam, M., Tsutsumi, Y.M., Bonds, J.A., Horikawa, Y.T., Saldana, M., Dalton, N.D., Head, B.P., Patel, P.M., Roth, D.M., Patel, H.H., Dark chocolate receptors: epicatechin-induced cardiac protection is dependent on delta-opioid receptor stimulation. Am. J. Physiol. Heart Circ. Physiol. 299 (2010), H1604–H1609 https://doi.org/10.1152/ajpheart.00073.2010.
-
(2010)
Am. J. Physiol. Heart Circ. Physiol.
, vol.299
, pp. H1604-H1609
-
-
Panneerselvam, M.1
Tsutsumi, Y.M.2
Bonds, J.A.3
Horikawa, Y.T.4
Saldana, M.5
Dalton, N.D.6
Head, B.P.7
Patel, P.M.8
Roth, D.M.9
Patel, H.H.10
-
105
-
-
84928009064
-
(-)-Epicatechin prevents alterations in the metabolism of superoxide anion and nitric oxide in the hearts of L-NAME-treated rats
-
Piotrkowski, B., Calabró V., Galleano, M., Fraga, C.G., (-)-Epicatechin prevents alterations in the metabolism of superoxide anion and nitric oxide in the hearts of L-NAME-treated rats. Food Funct. 6 (2015), 155–161 https://doi.org/10.1039/c4fo00554f.
-
(2015)
Food Funct.
, vol.6
, pp. 155-161
-
-
Piotrkowski, B.1
Calabró, V.2
Galleano, M.3
Fraga, C.G.4
-
106
-
-
85007107358
-
LPS-induced renal inflammation is prevented by (-)-epicatechin in rats
-
Prince, P.D., Fischerman, L., Toblli, J.E., Fraga, C.G., Galleano, M., LPS-induced renal inflammation is prevented by (-)-epicatechin in rats. Redox Biol. 11 (2017), 342–349 https://doi.org/10.1016/j.redox.2016.12.023.
-
(2017)
Redox Biol.
, vol.11
, pp. 342-349
-
-
Prince, P.D.1
Fischerman, L.2
Toblli, J.E.3
Fraga, C.G.4
Galleano, M.5
-
107
-
-
84947967500
-
Dietary (-)-epicatechin mitigates oxidative stress, NO metabolism alterations, and inflammation in renal cortex from fructose-fed rats
-
Prince, P.D., Lanzi, C.R., Toblli, J.E., Elesgaray, R., Oteiza, P.I., Fraga, C.G., Galleano, M., Dietary (-)-epicatechin mitigates oxidative stress, NO metabolism alterations, and inflammation in renal cortex from fructose-fed rats. Free Radic. Biol. Med. 90 (2016), 35–46 https://doi.org/10.1016/j.freeradbiomed.2015.11.009.
-
(2016)
Free Radic. Biol. Med.
, vol.90
, pp. 35-46
-
-
Prince, P.D.1
Lanzi, C.R.2
Toblli, J.E.3
Elesgaray, R.4
Oteiza, P.I.5
Fraga, C.G.6
Galleano, M.7
-
108
-
-
84885174559
-
Analysis of the mechanisms underlying the antinociceptive effect of epicatechin in diabetic rats
-
Quiñonez-Bastidas, G.N., Cervantes-Durán, C., Rocha-González, H.I., Murbartián, J., Granados-Soto, V., Analysis of the mechanisms underlying the antinociceptive effect of epicatechin in diabetic rats. Life Sci. 93 (2013), 637–645 https://doi.org/10.1016/j.lfs.2013.08.022.
-
(2013)
Life Sci.
, vol.93
, pp. 637-645
-
-
Quiñonez-Bastidas, G.N.1
Cervantes-Durán, C.2
Rocha-González, H.I.3
Murbartián, J.4
Granados-Soto, V.5
-
109
-
-
85020316727
-
Antinociceptive effect of (-)-epicatechin in inflammatory and neuropathic pain in rats
-
Quiñonez-Bastidas, G.N., Pineda-Farias, J.B., Flores-Murrieta, F.J., Rodríguez-Silverio, J., Reyes-García, J.G., Godínez-Chaparro, B., Granados-Soto, V., Rocha-González, H.I., Antinociceptive effect of (-)-epicatechin in inflammatory and neuropathic pain in rats. Behav. Pharmacol., 2017 https://doi.org/10.1097/FBP.0000000000000320.
-
(2017)
Behav. Pharmacol.
-
-
Quiñonez-Bastidas, G.N.1
Pineda-Farias, J.B.2
Flores-Murrieta, F.J.3
Rodríguez-Silverio, J.4
Reyes-García, J.G.5
Godínez-Chaparro, B.6
Granados-Soto, V.7
Rocha-González, H.I.8
-
110
-
-
77952951185
-
(-)-Epicatechin activation of endothelial cell endothelial nitric oxide synthase, nitric oxide, and related signaling pathways
-
Ramirez-Sanchez, I., Maya, L., Ceballos, G., Villarreal, F., (-)-Epicatechin activation of endothelial cell endothelial nitric oxide synthase, nitric oxide, and related signaling pathways. Hypertension 55 (2010), 1398–1405 https://doi.org/10.1161/HYPERTENSIONAHA.109.147892.
-
(2010)
Hypertension
, vol.55
, pp. 1398-1405
-
-
Ramirez-Sanchez, I.1
Maya, L.2
Ceballos, G.3
Villarreal, F.4
-
111
-
-
84964323832
-
(-)-Epicatechin-induced recovery of mitochondria from simulated diabetes: potential role of endothelial nitric oxide synthase
-
Ramírez-Sánchez, I., Rodríguez, A., Moreno-Ulloa, A., Ceballos, G., Villarreal, F., (-)-Epicatechin-induced recovery of mitochondria from simulated diabetes: potential role of endothelial nitric oxide synthase. Diabetes Vasc. Dis. Res. 13 (2016), 201–210 https://doi.org/10.1177/1479164115620982.
-
(2016)
Diabetes Vasc. Dis. Res.
, vol.13
, pp. 201-210
-
-
Ramírez-Sánchez, I.1
Rodríguez, A.2
Moreno-Ulloa, A.3
Ceballos, G.4
Villarreal, F.5
-
112
-
-
84886241944
-
(-)-Epicatechin rich cocoa mediated modulation of oxidative stress regulators in skeletal muscle of heart failure and type 2 diabetes patients
-
Ramirez-Sanchez, I., Taub, P.R., Ciaraldi, T.P., Nogueira, L., Coe, T., Perkins, G., Hogan, M., Maisel, A.S., Henry, R.R., Ceballos, G., Villarreal, F., (-)-Epicatechin rich cocoa mediated modulation of oxidative stress regulators in skeletal muscle of heart failure and type 2 diabetes patients. Int. J. Cardiol. 168 (2013), 3982–3990 https://doi.org/10.1016/j.ijcard.2013.06.089.
-
(2013)
Int. J. Cardiol.
, vol.168
, pp. 3982-3990
-
-
Ramirez-Sanchez, I.1
Taub, P.R.2
Ciaraldi, T.P.3
Nogueira, L.4
Coe, T.5
Perkins, G.6
Hogan, M.7
Maisel, A.S.8
Henry, R.R.9
Ceballos, G.10
Villarreal, F.11
-
113
-
-
84954453639
-
Vasculoprotective effects of dietary cocoa flavanols in patients on hemodialysis: a double-blind, randomized, placebo-controlled trial
-
Rassaf, T., Rammos, C., Hendgen-Cotta, U.B., Heiss, C., Kleophas, W., Dellanna, F., Floege, J., Hetzel, G.R., Kelm, M., Vasculoprotective effects of dietary cocoa flavanols in patients on hemodialysis: a double-blind, randomized, placebo-controlled trial. Clin. J. Am. Soc. Nephrol. 11 (2016), 108–118 https://doi.org/10.2215/CJN.05560515.
-
(2016)
Clin. J. Am. Soc. Nephrol.
, vol.11
, pp. 108-118
-
-
Rassaf, T.1
Rammos, C.2
Hendgen-Cotta, U.B.3
Heiss, C.4
Kleophas, W.5
Dellanna, F.6
Floege, J.7
Hetzel, G.R.8
Kelm, M.9
-
114
-
-
85010988962
-
Differentiated Caco-2 cell monolayers exhibit adaptation in the transport and metabolism of flavan-3-ols with chronic exposure to both isolated flavan-3-ols and enriched extracts
-
Redan, B.W., Chegeni, M., Ferruzzi, M.G., Differentiated Caco-2 cell monolayers exhibit adaptation in the transport and metabolism of flavan-3-ols with chronic exposure to both isolated flavan-3-ols and enriched extracts. Food Funct. 8 (2017), 111–121 https://doi.org/10.1039/c6fo01289b.
-
(2017)
Food Funct.
, vol.8
, pp. 111-121
-
-
Redan, B.W.1
Chegeni, M.2
Ferruzzi, M.G.3
-
115
-
-
0033867415
-
Epicatechin in human plasma: in vivo determination and effect of chocolate consumption on plasma oxidation status
-
Rein, D., Lotito, S., Holt, R.R., Keen, C.L., Schmitz, H.H., Fraga, C.G., Epicatechin in human plasma: in vivo determination and effect of chocolate consumption on plasma oxidation status. J. Nutr. 130 (2000), 2109S–2114S.
-
(2000)
J. Nutr.
, vol.130
, pp. 2109S-2114S
-
-
Rein, D.1
Lotito, S.2
Holt, R.R.3
Keen, C.L.4
Schmitz, H.H.5
Fraga, C.G.6
-
116
-
-
70349876563
-
Dietary polyphenols generate nitric oxide from nitrite in the stomach and induce smooth muscle relaxation
-
Rocha, B.S., Gago, B., Barbosa, R.M., Laranjinha, J., Dietary polyphenols generate nitric oxide from nitrite in the stomach and induce smooth muscle relaxation. Toxicology 265 (2009), 41–48 https://doi.org/10.1016/j.tox.2009.09.008.
-
(2009)
Toxicology
, vol.265
, pp. 41-48
-
-
Rocha, B.S.1
Gago, B.2
Barbosa, R.M.3
Laranjinha, J.4
-
117
-
-
84856266699
-
Intragastric nitration by dietary nitrite: implications for modulation of protein and lipid signaling
-
Rocha, B.S., Gago, B., Barbosa, R.M., Lundberg, J.O., Radi, R., Laranjinha, J., Intragastric nitration by dietary nitrite: implications for modulation of protein and lipid signaling. Free Radic. Biol. Med. 52 (2012), 693–698 https://doi.org/10.1016/j.freeradbiomed.2011.11.011.
-
(2012)
Free Radic. Biol. Med.
, vol.52
, pp. 693-698
-
-
Rocha, B.S.1
Gago, B.2
Barbosa, R.M.3
Lundberg, J.O.4
Radi, R.5
Laranjinha, J.6
-
118
-
-
84938500112
-
Influence of age on the absorption, metabolism, and excretion of cocoa flavanols in healthy subjects
-
Rodriguez-Mateos, A., Cifuentes-Gomez, T., Gonzalez-Salvador, I., Ottaviani, J.I., Schroeter, H., Kelm, M., Heiss, C., Spencer, J.P.E., Influence of age on the absorption, metabolism, and excretion of cocoa flavanols in healthy subjects. Mol. Nutr. Food Res. 59 (2015), 1504–1512 https://doi.org/10.1002/mnfr.201500091.
-
(2015)
Mol. Nutr. Food Res.
, vol.59
, pp. 1504-1512
-
-
Rodriguez-Mateos, A.1
Cifuentes-Gomez, T.2
Gonzalez-Salvador, I.3
Ottaviani, J.I.4
Schroeter, H.5
Kelm, M.6
Heiss, C.7
Spencer, J.P.E.8
-
119
-
-
0024997241
-
Transcriptional regulation of the rat glutathione S-transferase Ya subunit gene. Characterization of a xenobiotic-responsive element controlling inducible expression by phenolic antioxidants
-
Rushmore, T.H., Pickett, C.B., Transcriptional regulation of the rat glutathione S-transferase Ya subunit gene. Characterization of a xenobiotic-responsive element controlling inducible expression by phenolic antioxidants. J. Biol. Chem. 265 (1990), 14648–14653.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 14648-14653
-
-
Rushmore, T.H.1
Pickett, C.B.2
-
120
-
-
85011636506
-
Methylxanthines enhance the effects of cocoa flavanols on cardiovascular function: randomized, double-masked controlled studies
-
Sansone, R., Ottaviani, J.I., Rodriguez-Mateos, A., Heinen, Y., Noske, D., Spencer, J.P., Crozier, A., Merx, M.W., Kelm, M., Schroeter, H., Heiss, C., Methylxanthines enhance the effects of cocoa flavanols on cardiovascular function: randomized, double-masked controlled studies. Am. J. Clin. Nutr. 105 (2017), 352–360 https://doi.org/10.3945/ajcn.116.140046.
-
(2017)
Am. J. Clin. Nutr.
, vol.105
, pp. 352-360
-
-
Sansone, R.1
Ottaviani, J.I.2
Rodriguez-Mateos, A.3
Heinen, Y.4
Noske, D.5
Spencer, J.P.6
Crozier, A.7
Merx, M.W.8
Kelm, M.9
Schroeter, H.10
Heiss, C.11
-
121
-
-
84973897659
-
Inhibitory effects of eight green tea catechins on cytochrome P450 1A2, 2C9, 2D6, and 3A4 activities
-
Satoh, T., Fujisawa, H., Nakamura, A., Takahashi, N., Watanabe, K., Inhibitory effects of eight green tea catechins on cytochrome P450 1A2, 2C9, 2D6, and 3A4 activities. J. Pharm. Pharmaceut. Sci. 19 (2016), 188–197.
-
(2016)
J. Pharm. Pharmaceut. Sci.
, vol.19
, pp. 188-197
-
-
Satoh, T.1
Fujisawa, H.2
Nakamura, A.3
Takahashi, N.4
Watanabe, K.5
-
122
-
-
48049106159
-
How do dietary flavanols improve vascular function? A position paper
-
Schewe, T., Steffen, Y., Sies, H., How do dietary flavanols improve vascular function? A position paper. Arch. Biochem. Biophys. 476 (2008), 102–106 https://doi.org/10.1016/j.abb.2008.03.004.
-
(2008)
Arch. Biochem. Biophys.
, vol.476
, pp. 102-106
-
-
Schewe, T.1
Steffen, Y.2
Sies, H.3
-
123
-
-
85015983040
-
Organizers and activators: cytosolic Nox proteins impacting on vascular function
-
Schröder, K., Weissmann, N., Brandes, R.P., Organizers and activators: cytosolic Nox proteins impacting on vascular function. Free Radic. Biol. Med. 109 (2017), 22–32 https://doi.org/10.1016/j.freeradbiomed.2017.03.017.
-
(2017)
Free Radic. Biol. Med.
, vol.109
, pp. 22-32
-
-
Schröder, K.1
Weissmann, N.2
Brandes, R.P.3
-
124
-
-
32244437985
-
(-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans
-
Schroeter, H., Heiss, C., Balzer, J., Kleinbongard, P., Keen, C.L., Hollenberg, N.K., Sies, H., Kwik-Uribe, C., Schmitz, H.H., Kelm, M., (-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans. Proc. Natl. Acad. Sci. U. S. A 103 (2006), 1024–1029 https://doi.org/10.1073/pnas.0510168103.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A
, vol.103
, pp. 1024-1029
-
-
Schroeter, H.1
Heiss, C.2
Balzer, J.3
Kleinbongard, P.4
Keen, C.L.5
Hollenberg, N.K.6
Sies, H.7
Kwik-Uribe, C.8
Schmitz, H.H.9
Kelm, M.10
-
125
-
-
78649710411
-
The flavanol (-)-epicatechin prevents stroke damage through the Nrf2/HO1 pathway
-
Shah, Z.A., Li, R., Ahmad, A.S., Kensler, T.W., Yamamoto, M., Biswal, S., Doré S., The flavanol (-)-epicatechin prevents stroke damage through the Nrf2/HO1 pathway. J. Cerebr. Blood Flow Metabol. 30 (2010), 1951–1961 https://doi.org/10.1038/jcbfm.2010.53.
-
(2010)
J. Cerebr. Blood Flow Metabol.
, vol.30
, pp. 1951-1961
-
-
Shah, Z.A.1
Li, R.2
Ahmad, A.S.3
Kensler, T.W.4
Yamamoto, M.5
Biswal, S.6
Doré, S.7
-
126
-
-
85009877414
-
Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: oxidative eustress
-
Sies, H., Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: oxidative eustress. Redox Biol. 11 (2017), 613–619 https://doi.org/10.1016/j.redox.2016.12.035.
-
(2017)
Redox Biol.
, vol.11
, pp. 613-619
-
-
Sies, H.1
-
127
-
-
78649636576
-
Dietary isoflavones and vascular protection: activation of cellular antioxidant defenses by SERMs or hormesis?
-
Siow, R.C.M., Mann, G.E., Dietary isoflavones and vascular protection: activation of cellular antioxidant defenses by SERMs or hormesis?. Mol. Aspect. Med. 31 (2010), 468–477 https://doi.org/10.1016/j.mam.2010.09.003.
-
(2010)
Mol. Aspect. Med.
, vol.31
, pp. 468-477
-
-
Siow, R.C.M.1
Mann, G.E.2
-
128
-
-
84873568286
-
(-) Epicatechin attenuates mitochondrial damage by enhancing mitochondrial multi-marker enzymes, adenosine triphosphate and lowering calcium in isoproterenol induced myocardial infarcted rats
-
Stanely Mainzen Prince, P., (-) Epicatechin attenuates mitochondrial damage by enhancing mitochondrial multi-marker enzymes, adenosine triphosphate and lowering calcium in isoproterenol induced myocardial infarcted rats. Food Chem. Toxicol. Int. 53 (2013), 409–416 https://doi.org/10.1016/j.fct.2012.12.010.
-
(2013)
Food Chem. Toxicol. Int.
, vol.53
, pp. 409-416
-
-
Stanely Mainzen Prince, P.1
-
129
-
-
37549011857
-
Mono-O-methylated flavanols and other flavonoids as inhibitors of endothelial NADPH oxidase
-
Steffen, Y., Gruber, C., Schewe, T., Sies, H., Mono-O-methylated flavanols and other flavonoids as inhibitors of endothelial NADPH oxidase. Arch. Biochem. Biophys. 469 (2008), 209–219 https://doi.org/10.1016/j.abb.2007.10.012.
-
(2008)
Arch. Biochem. Biophys.
, vol.469
, pp. 209-219
-
-
Steffen, Y.1
Gruber, C.2
Schewe, T.3
Sies, H.4
-
130
-
-
34250212563
-
(-)-Epicatechin elevates nitric oxide in endothelial cells via inhibition of NADPH oxidase
-
Steffen, Y., Schewe, T., Sies, H., (-)-Epicatechin elevates nitric oxide in endothelial cells via inhibition of NADPH oxidase. Biochem. Biophys. Res. Commun. 359 (2007), 828–833 https://doi.org/10.1016/j.bbrc.2007.05.200.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.359
, pp. 828-833
-
-
Steffen, Y.1
Schewe, T.2
Sies, H.3
-
131
-
-
84868369214
-
Epicatechin limits renal injury by mitochondrial protection in cisplatin nephropathy
-
Tanabe, K., Tamura, Y., Lanaspa, M.A., Miyazaki, M., Suzuki, N., Sato, W., Maeshima, Y., Schreiner, G.F., Villarreal, F.J., Johnson, R.J., Nakagawa, T., Epicatechin limits renal injury by mitochondrial protection in cisplatin nephropathy. Am. J. Physiol. Ren. Physiol. 303 (2012), F1264–F1274 https://doi.org/10.1152/ajprenal.00227.2012.
-
(2012)
Am. J. Physiol. Ren. Physiol.
, vol.303
, pp. F1264-F1274
-
-
Tanabe, K.1
Tamura, Y.2
Lanaspa, M.A.3
Miyazaki, M.4
Suzuki, N.5
Sato, W.6
Maeshima, Y.7
Schreiner, G.F.8
Villarreal, F.J.9
Johnson, R.J.10
Nakagawa, T.11
-
132
-
-
84857649267
-
Alterations in skeletal muscle indicators of mitochondrial structure and biogenesis in patients with type 2 diabetes and heart failure: effects of epicatechin rich cocoa
-
Taub, P.R., Ramirez-Sanchez, I., Ciaraldi, T.P., Perkins, G., Murphy, A.N., Naviaux, R., Hogan, M., Maisel, A.S., Henry, R.R., Ceballos, G., Villarreal, F., Alterations in skeletal muscle indicators of mitochondrial structure and biogenesis in patients with type 2 diabetes and heart failure: effects of epicatechin rich cocoa. Clin. Transl. Sci. 5 (2012), 43–47 https://doi.org/10.1111/j.1752-8062.2011.00357.x.
-
(2012)
Clin. Transl. Sci.
, vol.5
, pp. 43-47
-
-
Taub, P.R.1
Ramirez-Sanchez, I.2
Ciaraldi, T.P.3
Perkins, G.4
Murphy, A.N.5
Naviaux, R.6
Hogan, M.7
Maisel, A.S.8
Henry, R.R.9
Ceballos, G.10
Villarreal, F.11
-
133
-
-
84927662178
-
Interactions of flavan-3-ols and procyanidins with membranes: mechanisms and the physiological relevance
-
Verstraeten, S.V., Fraga, C.G., Oteiza, P.I., Interactions of flavan-3-ols and procyanidins with membranes: mechanisms and the physiological relevance. Food Funct. 6 (2015), 32–41 https://doi.org/10.1039/c4fo00647j.
-
(2015)
Food Funct.
, vol.6
, pp. 32-41
-
-
Verstraeten, S.V.1
Fraga, C.G.2
Oteiza, P.I.3
-
134
-
-
21644464080
-
Antioxidant and membrane effects of procyanidin dimers and trimers isolated from peanut and cocoa
-
Verstraeten, S.V., Hammerstone, J.F., Keen, C.L., Fraga, C.G., Oteiza, P.I., Antioxidant and membrane effects of procyanidin dimers and trimers isolated from peanut and cocoa. J. Agric. Food Chem. 53 (2005), 5041–5048 https://doi.org/10.1021/jf058018m.
-
(2005)
J. Agric. Food Chem.
, vol.53
, pp. 5041-5048
-
-
Verstraeten, S.V.1
Hammerstone, J.F.2
Keen, C.L.3
Fraga, C.G.4
Oteiza, P.I.5
-
135
-
-
84881488637
-
Procyanidins can interact with Caco-2 cell membrane lipid rafts: involvement of cholesterol
-
Verstraeten, S.V., Jaggers, G.K., Fraga, C.G., Oteiza, P.I., Procyanidins can interact with Caco-2 cell membrane lipid rafts: involvement of cholesterol. Biochim. Biophys. Acta 1828 (2013), 2646–2653 https://doi.org/10.1016/j.bbamem.2013.07.023.
-
(2013)
Biochim. Biophys. Acta
, vol.1828
, pp. 2646-2653
-
-
Verstraeten, S.V.1
Jaggers, G.K.2
Fraga, C.G.3
Oteiza, P.I.4
-
136
-
-
12244287615
-
Flavan-3-ols and procyanidins protect liposomes against lipid oxidation and disruption of the bilayer structure
-
Verstraeten, S.V., Keen, C.L., Schmitz, H.H., Fraga, C.G., Oteiza, P.I., Flavan-3-ols and procyanidins protect liposomes against lipid oxidation and disruption of the bilayer structure. Free Radic. Biol. Med. 34 (2003), 84–92.
-
(2003)
Free Radic. Biol. Med.
, vol.34
, pp. 84-92
-
-
Verstraeten, S.V.1
Keen, C.L.2
Schmitz, H.H.3
Fraga, C.G.4
Oteiza, P.I.5
-
137
-
-
55849145504
-
(-)-Epicatechin and related procyanidins modulate intracellular calcium and prevent oxidation in Jurkat T cells
-
Verstraeten, S.V., Mackenzie, G.G., Oteiza, P.I., Fraga, C.G., (-)-Epicatechin and related procyanidins modulate intracellular calcium and prevent oxidation in Jurkat T cells. Free Radic. Res. 42 (2008), 864–872 https://doi.org/10.1080/10715760802471452.
-
(2008)
Free Radic. Res.
, vol.42
, pp. 864-872
-
-
Verstraeten, S.V.1
Mackenzie, G.G.2
Oteiza, P.I.3
Fraga, C.G.4
-
138
-
-
82255173966
-
The unfolded protein response: from stress pathway to homeostatic regulation
-
Walter, P., Ron, D., The unfolded protein response: from stress pathway to homeostatic regulation. Science 334 (2011), 1081–1086 https://doi.org/10.1126/science.1209038.
-
(2011)
Science
, vol.334
, pp. 1081-1086
-
-
Walter, P.1
Ron, D.2
-
139
-
-
0033867144
-
A dose-response effect from chocolate consumption on plasma epicatechin and oxidative damage
-
Wang, J.F., Schramm, D.D., Holt, R.R., Ensunsa, J.L., Fraga, C.G., Schmitz, H.H., Keen, C.L., A dose-response effect from chocolate consumption on plasma epicatechin and oxidative damage. J. Nutr. 130 (2000), 2115S–2119S.
-
(2000)
J. Nutr.
, vol.130
, pp. 2115S-2119S
-
-
Wang, J.F.1
Schramm, D.D.2
Holt, R.R.3
Ensunsa, J.L.4
Fraga, C.G.5
Schmitz, H.H.6
Keen, C.L.7
-
140
-
-
85016058326
-
Role of the small intestine, colon and microbiota in determining the metabolic fate of polyphenols
-
Williamson, G., Clifford, M.N., Role of the small intestine, colon and microbiota in determining the metabolic fate of polyphenols. Biochem. Pharmacol. 139 (2017), 24–39 https://doi.org/10.1016/j.bcp.2017.03.012.
-
(2017)
Biochem. Pharmacol.
, vol.139
, pp. 24-39
-
-
Williamson, G.1
Clifford, M.N.2
-
141
-
-
84924119180
-
Are free radicals involved in thiol-based redox signaling?
-
Winterbourn, C.C., Are free radicals involved in thiol-based redox signaling?. Free Radic. Biol. Med. 80 (2015), 164–170 https://doi.org/10.1016/j.freeradbiomed.2014.08.017.
-
(2015)
Free Radic. Biol. Med.
, vol.80
, pp. 164-170
-
-
Winterbourn, C.C.1
-
142
-
-
48449107159
-
Thiol chemistry and specificity in redox signaling
-
Winterbourn, C.C., Hampton, M.B., Thiol chemistry and specificity in redox signaling. Free Radic. Biol. Med. 45 (2008), 549–561 https://doi.org/10.1016/j.freeradbiomed.2008.05.004.
-
(2008)
Free Radic. Biol. Med.
, vol.45
, pp. 549-561
-
-
Winterbourn, C.C.1
Hampton, M.B.2
-
143
-
-
84904254220
-
Intravenous (-)-epicatechin reduces myocardial ischemic injury by protecting mitochondrial function
-
Yamazaki, K.G., Andreyev, A.Y., Ortiz-Vilchis, P., Petrosyan, S., Divakaruni, A.S., Wiley, S.E., De La Fuente, C., Perkins, G., Ceballos, G., Villarreal, F., Murphy, A.N., Intravenous (-)-epicatechin reduces myocardial ischemic injury by protecting mitochondrial function. Int. J. Cardiol. 175 (2014), 297–306 https://doi.org/10.1016/j.ijcard.2014.05.009.
-
(2014)
Int. J. Cardiol.
, vol.175
, pp. 297-306
-
-
Yamazaki, K.G.1
Andreyev, A.Y.2
Ortiz-Vilchis, P.3
Petrosyan, S.4
Divakaruni, A.S.5
Wiley, S.E.6
De La Fuente, C.7
Perkins, G.8
Ceballos, G.9
Villarreal, F.10
Murphy, A.N.11
-
144
-
-
84926631100
-
Mitochondria: the cellular hub of the dynamic coordinated network
-
Yin, F., Cadenas, E., Mitochondria: the cellular hub of the dynamic coordinated network. Antioxidants Redox Signal. 22 (2015), 961–964 https://doi.org/10.1089/ars.2015.6313.
-
(2015)
Antioxidants Redox Signal.
, vol.22
, pp. 961-964
-
-
Yin, F.1
Cadenas, E.2
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