Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 479, Issue 1-2, 2001, Pages 197-206

  Muto, Shigeharu ^a   Fujita, Ken Ichi ^a   Yamazaki, Yoshiyuki ^a   Kamataki, Tetsuya ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Antimutagenicity; Chemoprevention; EGCG

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; 4 NITROPHENOL; 7 ETHOXYCOUMARIN; AFLATOXIN B1; BENZO[A]PYRENE; CARCINOGEN; COUMARIN 7 HYDROXYLASE; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2A6; CYTOCHROME P450 2C19; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; DICLOFENAC; EPICATECHIN; EPICATECHIN GALLATE; EPIGALLOCATECHIN; EPIGALLOCATECHIN GALLATE; ETHOXYRESORUFIN; MIDAZOLAM; PROMUTAGEN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE; UNSPECIFIC MONOOXYGENASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HYDROXYLATION; IC 50; METABOLIC ACTIVATION; MUTAGENIC ACTIVITY; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SALMONELLA TYPHIMURIUM; TEA;

AFLATOXIN B1; ANTICARCINOGENIC AGENTS; ANTIOXIDANTS; BENZO(A)PYRENE; BEVERAGES; CARCINOGENS; CATECHIN; CELL MEMBRANE; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; IMIDAZOLES; KINETICS; MIXED FUNCTION OXYGENASES; MUTAGENESIS; NADPH-FERRIHEMOPROTEIN REDUCTASE; PROTEIN BINDING; SALMONELLA TYPHIMURIUM;

RODENTIA; SALMONELLA TYPHIMURIUM; TYPHIMURIUM;

EID: 0035828180     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(01)00204-4     Document Type: Article

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