Complex I and cytochrome c are molecular targets of flavonoids that inhibit hydrogen peroxide production by mitochondria

Biochimica et Biophysica Acta - Bioenergetics

Volumn 1807, Issue 12, 2011, Pages 1562-1572

  Lagoa, Ricardo ^a,b   Graziani, Ilaria ^a,c   Lopez Sanchez, Carmen ^a   Garcia Martinez, Virginio ^a   Gutierrez Merino, Carlos ^a  

^a UNIVERSITY OF EXTREMADURA   (Spain)

^b POLYTECHNIC INSTITUTE OF LEIRIA   (Portugal)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

Complex I; Cytochrome c; Flavonoid; Hydrogen peroxide production; Mitochondria; Ubiquinone

Indexed keywords

ANTIMYCIN A1; APIGENIN; CYTOCHROME C; EPICATECHIN; FLAVONOID; HYDROGEN PEROXIDE; KAEMPFEROL; MITOCHONDRIAL ENZYME; QUERCETIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE; SUPEROXIDE DISMUTASE; UBIQUINONE;

ABSORPTION SPECTROSCOPY; ANIMAL TISSUE; ARTICLE; BINDING SITE; BRAIN MITOCHONDRION; ENZYME ACTIVITY; ENZYME PURIFICATION; HEART MITOCHONDRION; MITOCHONDRION; NONHUMAN; OXIDATION REDUCTION REACTION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIMYCIN A; ANTIOXIDANTS; APIGENIN; BRAIN; CATECHIN; CYTOCHROMES C; ELECTRON TRANSPORT COMPLEX I; FLAVONOIDS; HEART; HYDROGEN PEROXIDE; KAEMPFEROLS; MITOCHONDRIA; OXIDANTS; OXIDATION-REDUCTION; OXYGEN CONSUMPTION; QUERCETIN; RATS; RATS, WISTAR; ROTENONE; UBIQUINONE; UNCOUPLING AGENTS;

RATTUS;

EID: 81155128482     PISSN: 00052728     EISSN: 18792650     Source Type: Journal    
DOI: 10.1016/j.bbabio.2011.09.022     Document Type: Article

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