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Volumn 59, Issue 8, 2015, Pages 1504-1512

Influence of age on the absorption, metabolism, and excretion of cocoa flavanols in healthy subjects

Author keywords

( ) Epicatechin; ADME; Age; Cocoa flavanols; Pharmacokinetics

Indexed keywords

THEOBROMA CACAO;

EID: 84938500112     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201500091     Document Type: Article
Times cited : (52)

References (25)
  • 1
    • 78149327504 scopus 로고    scopus 로고
    • Flavanols and cardiovascular disease prevention
    • Heiss, C., Keen, C. L., Kelm, M., Flavanols and cardiovascular disease prevention. Eur. Heart J. 2010, 31, 2583-2592.
    • (2010) Eur. Heart J. , vol.31 , pp. 2583-2592
    • Heiss, C.1    Keen, C.L.2    Kelm, M.3
  • 2
    • 84857892715 scopus 로고    scopus 로고
    • Effects of chocolate, cocoa, and flavan-3-ols on cardiovascular health: a systematic review and meta-analysis of randomized trials
    • Hooper, L., Kay, C., Abdelhamid, A., Kroon, P. A. et al., Effects of chocolate, cocoa, and flavan-3-ols on cardiovascular health: a systematic review and meta-analysis of randomized trials. Am. J. Clin. Nutr. 2012, 95, 740-751.
    • (2012) Am. J. Clin. Nutr. , vol.95 , pp. 740-751
    • Hooper, L.1    Kay, C.2    Abdelhamid, A.3    Kroon, P.A.4
  • 4
    • 84864397350 scopus 로고    scopus 로고
    • Elucidation of (-)-epicatechin metabolites after ingestion of chocolate by healthy humans
    • Actis-Goretta, L., Leveques, A., Giuffrida, F., Romanov-Michailidis, F. et al., Elucidation of (-)-epicatechin metabolites after ingestion of chocolate by healthy humans. Free Rad. Biol. Med. 2012, 53, 787-795.
    • (2012) Free Rad. Biol. Med. , vol.53 , pp. 787-795
    • Actis-Goretta, L.1    Leveques, A.2    Giuffrida, F.3    Romanov-Michailidis, F.4
  • 5
    • 84859010162 scopus 로고    scopus 로고
    • Structurally related (-)-epicatechin metabolites in humans: assessment using de novo chemically synthesized authentic standards
    • Ottaviani, J. I., Momma, T. Y., Kuhnle, G. K., Keen, C. L., Schroeter, H., Structurally related (-)-epicatechin metabolites in humans: assessment using de novo chemically synthesized authentic standards. Free Rad. Biol. Med. 2012, 52, 1403-1412.
    • (2012) Free Rad. Biol. Med. , vol.52 , pp. 1403-1412
    • Ottaviani, J.I.1    Momma, T.Y.2    Kuhnle, G.K.3    Keen, C.L.4    Schroeter, H.5
  • 6
    • 84859048094 scopus 로고    scopus 로고
    • Intake of dietary procyanidins does not contribute to the pool of circulating flavanols in humans
    • Ottaviani, J. I., Kwik-Uribe, C., Keen, C. L., Schroeter, H., Intake of dietary procyanidins does not contribute to the pool of circulating flavanols in humans. Am. J. Clin. Nutr. 2012, 95, 851-858.
    • (2012) Am. J. Clin. Nutr. , vol.95 , pp. 851-858
    • Ottaviani, J.I.1    Kwik-Uribe, C.2    Keen, C.L.3    Schroeter, H.4
  • 7
    • 0142155211 scopus 로고    scopus 로고
    • Development and optimization of a reversed-phase high-performance liquid chromatographic method for the determination of acetaminophen and its major metabolites in rabbit plasma and urine after a toxic dose
    • Vertzoni, M. V., Archontaki, H. A., Galanopoulou, P., Development and optimization of a reversed-phase high-performance liquid chromatographic method for the determination of acetaminophen and its major metabolites in rabbit plasma and urine after a toxic dose. J. Pharm. Biomed. Anal. 2003, 32, 487-493.
    • (2003) J. Pharm. Biomed. Anal. , vol.32 , pp. 487-493
    • Vertzoni, M.V.1    Archontaki, H.A.2    Galanopoulou, P.3
  • 10
    • 84875953344 scopus 로고    scopus 로고
    • Dietary (poly)phenolics in human health: structures, bioavailability, and evidence of protective effects against chronic diseases
    • Del Rio D., Rodriguez-Mateos, A., Spencer, J.P., Tognolini, M., Borges, G., Crozier, A., Dietary (poly)phenolics in human health: structures, bioavailability, and evidence of protective effects against chronic diseases. Antioxid. Redox Signal. 2013, 18, 1818-1892.
    • (2013) Antioxid. Redox Signal. , vol.18 , pp. 1818-1892
    • Del Rio, D.1    Rodriguez-Mateos, A.2    Spencer, J.P.3    Tognolini, M.4    Borges, G.5    Crozier, A.6
  • 11
    • 0037228105 scopus 로고    scopus 로고
    • Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey
    • Coresh, J., Astor, B.C., Greene, T., Eknoyan, G., Levey, A.S. Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey. Am. J. Kidney Dis. 2003, 41:1-12.
    • (2003) Am. J. Kidney Dis. , vol.41 , pp. 1-12
    • Coresh, J.1    Astor, B.C.2    Greene, T.3    Eknoyan, G.4    Levey, A.S.5
  • 12
    • 2942592005 scopus 로고    scopus 로고
    • Characterization of bacterial communities in feces from healthy elderly volunteers and hospitalized elderly patients by using real-time PCR and effects of antibiotic treatment on the fecal microbiota
    • Bartosch, S., Fite, A., Macfarlane, G. T., McMurdo, M. E., Characterization of bacterial communities in feces from healthy elderly volunteers and hospitalized elderly patients by using real-time PCR and effects of antibiotic treatment on the fecal microbiota. Appl. Environ. Microbiol. 2004, 70, 3575-3581.
    • (2004) Appl. Environ. Microbiol. , vol.70 , pp. 3575-3581
    • Bartosch, S.1    Fite, A.2    Macfarlane, G.T.3    McMurdo, M.E.4
  • 13
    • 0024510314 scopus 로고
    • Comparison of fecal microflora of elderly persons in rural and urban areas of Japan
    • Benno, Y., Endo, K., Mizutani, T., Namba, Y. et al., Comparison of fecal microflora of elderly persons in rural and urban areas of Japan. Appl. Environ. Microbiol. 1989, 55, 1100-1105.
    • (1989) Appl. Environ. Microbiol. , vol.55 , pp. 1100-1105
    • Benno, Y.1    Endo, K.2    Mizutani, T.3    Namba, Y.4
  • 14
    • 0042471955 scopus 로고    scopus 로고
    • Molecular analysis of fecal microbiota in elderly individuals using 16S rDNA library and T-RFLP
    • Hayashi, H., Sakamoto, M., Kitahara, M., Benno, Y., Molecular analysis of fecal microbiota in elderly individuals using 16S rDNA library and T-RFLP. Microbiol. Immunol. 2003, 47, 557-570.
    • (2003) Microbiol. Immunol. , vol.47 , pp. 557-570
    • Hayashi, H.1    Sakamoto, M.2    Kitahara, M.3    Benno, Y.4
  • 15
    • 33144460422 scopus 로고    scopus 로고
    • Differences in fecal microbiota in different European study populations in relation to age, gender, and country: a cross-sectional study
    • Mueller, S., Saunier, K., Hanisch, C., Norin, E. et al., Differences in fecal microbiota in different European study populations in relation to age, gender, and country: a cross-sectional study. Appl. Environ. Microbiol. 2006, 72, 1027-1033.
    • (2006) Appl. Environ. Microbiol. , vol.72 , pp. 1027-1033
    • Mueller, S.1    Saunier, K.2    Hanisch, C.3    Norin, E.4
  • 16
    • 53149150212 scopus 로고    scopus 로고
    • The effect of ageing with and without non-steroidal anti-inflammatory drugs on gastrointestinal microbiology and immunology
    • Tiihonen, K., Tynkkynen, S., Ouwehand, A., Ahlroos, T., Rautonen, N., The effect of ageing with and without non-steroidal anti-inflammatory drugs on gastrointestinal microbiology and immunology. Brit. J. Nutr. 2008, 100, 130-137.
    • (2008) Brit. J. Nutr. , vol.100 , pp. 130-137
    • Tiihonen, K.1    Tynkkynen, S.2    Ouwehand, A.3    Ahlroos, T.4    Rautonen, N.5
  • 17
    • 0034761174 scopus 로고    scopus 로고
    • Differences in composition and mucosal adhesion of bifidobacteria isolated from healthy adults and healthy seniors
    • He, F., Ouwehand, A. C., Isolauri, E., Hosoda, M. et al., Differences in composition and mucosal adhesion of bifidobacteria isolated from healthy adults and healthy seniors. Curr. Microbiol. 2001, 43, 351-354.
    • (2001) Curr. Microbiol. , vol.43 , pp. 351-354
    • He, F.1    Ouwehand, A.C.2    Isolauri, E.3    Hosoda, M.4
  • 18
    • 0035124967 scopus 로고    scopus 로고
    • Age and disease related changes in intestinal bacterial populations assessed by cell culture, 16S rRNA abundance, and community cellular fatty acid profiles
    • Hopkins, M. J., Sharp, R., Macfarlane, G. T., Age and disease related changes in intestinal bacterial populations assessed by cell culture, 16S rRNA abundance, and community cellular fatty acid profiles. Gut 2001, 48, 198-205.
    • (2001) Gut , vol.48 , pp. 198-205
    • Hopkins, M.J.1    Sharp, R.2    Macfarlane, G.T.3
  • 19
    • 0027094135 scopus 로고
    • Intestinal flora and aging
    • Mitsuoka, T., Intestinal flora and aging. Nutr. Rev. 1992, 50, 438-446.
    • (1992) Nutr. Rev. , vol.50 , pp. 438-446
    • Mitsuoka, T.1
  • 20
    • 84871545316 scopus 로고    scopus 로고
    • Isolation and characterization of a human intestinal bacterium Eggerthella sp. CAT-1 capable of cleaving the C-ring of (+)-catechin and (-)-epicatechin, followed by p-dehydroxylation of the B-ring
    • Jin, J. S., Hattori, M., Isolation and characterization of a human intestinal bacterium Eggerthella sp. CAT-1 capable of cleaving the C-ring of (+)-catechin and (-)-epicatechin, followed by p-dehydroxylation of the B-ring. Biol. Pharm. Bull. 2012, 35, 2252-2256.
    • (2012) Biol. Pharm. Bull. , vol.35 , pp. 2252-2256
    • Jin, J.S.1    Hattori, M.2
  • 21
    • 79958812230 scopus 로고    scopus 로고
    • Isolation of catechin-converting human intestinal bacteria
    • Kutschera, M., Engst, W., Blaut, M., Braune, A., Isolation of catechin-converting human intestinal bacteria. J. Appl. Microbiol. 2011, 111, 165-175.
    • (2011) J. Appl. Microbiol. , vol.111 , pp. 165-175
    • Kutschera, M.1    Engst, W.2    Blaut, M.3    Braune, A.4
  • 22
    • 27744449813 scopus 로고    scopus 로고
    • Acute consumption of flavanol-rich cocoa and the reversal of endothelial dysfunction in smokers
    • Heiss, C., Kleinbongard, P., Dejam, A., Perre, S. et al., Acute consumption of flavanol-rich cocoa and the reversal of endothelial dysfunction in smokers. J. Am. Coll. Cardiol. 2005, 46, 1276-1283.
    • (2005) J. Am. Coll. Cardiol. , vol.46 , pp. 1276-1283
    • Heiss, C.1    Kleinbongard, P.2    Dejam, A.3    Perre, S.4
  • 23
    • 32244437985 scopus 로고    scopus 로고
    • (-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans
    • Schroeter, H., Heiss, C., Balzer, J., Kleinbongard, P. et al., (-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans. Proc. Natl. Acad. Sci. USA 2006, 103, 1024-1029.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 1024-1029
    • Schroeter, H.1    Heiss, C.2    Balzer, J.3    Kleinbongard, P.4
  • 24
    • 84958177346 scopus 로고    scopus 로고
    • Scientific opinion on the substantiation of a health claim related to cocoa flavanols and maintenance of normalendothelium-dependent vasodilation pursuant to Article 13(5) of Regulation (EC) No. 1924/2006
    • EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). Scientific opinion on the substantiation of a health claim related to cocoa flavanols and maintenance of normalendothelium-dependent vasodilation pursuant to Article 13(5) of Regulation (EC) No. 1924/2006. EFSA J. 2012, 10, 2809-2830.
    • (2012) EFSA J. , vol.10 , pp. 2809-2830
  • 25
    • 84897114818 scopus 로고    scopus 로고
    • Assessment of the dietary intake of total flavan-3-ols, monomeric flavan-3-ols, proanthocyanidins and theaflavins in the European Union
    • Vogiatzoglou, A., Mulligan, A. A., Luben, R. N., Lentjes, M. A. et al., Assessment of the dietary intake of total flavan-3-ols, monomeric flavan-3-ols, proanthocyanidins and theaflavins in the European Union. Brit. J. Nutr. 2014, 111, 1463-1473.
    • (2014) Brit. J. Nutr. , vol.111 , pp. 1463-1473
    • Vogiatzoglou, A.1    Mulligan, A.A.2    Luben, R.N.3    Lentjes, M.A.4


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