-
1
-
-
0037115062
-
Uptake and metabolism of epicatechin and its access to the brain after oral ingestion
-
Abd El Mohsen MM, Kuhnle G, Rechner AR, Schroeter H, Rose S, Jenner P, Rice-Evans CA (2002) Uptake and metabolism of epicatechin and its access to the brain after oral ingestion. Free Radic Biol Med 33:1693-702
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 1693-702
-
-
Abd El Mohsen, M.M.1
Kuhnle, G.2
Rechner, A.R.3
Schroeter, H.4
Rose, S.5
Jenner, P.6
Rice-Evans, C.A.7
-
2
-
-
33747232569
-
Heme oxygenase-1 protects brain from acute excitotoxicity
-
Ahmad AS, Zhuang H, Doré S (2006) Heme oxygenase-1 protects brain from acute excitotoxicity. Neuroscience 141:1703-8
-
(2006)
Neuroscience
, vol.141
, pp. 1703-8
-
-
Ahmad, A.S.1
Zhuang, H.2
Doré, S.3
-
3
-
-
0029900542
-
ESR spin-trapping of a protein-derived tyrosyl radical from the reaction of cytochrome c with hydrogen peroxide
-
Barr DP, Gunther MR, Deterding LJ, Tomer KB, Mason RP (1996) ESR spin-trapping of a protein-derived tyrosyl radical from the reaction of cytochrome c with hydrogen peroxide. J Biol Chem 271:15498-503
-
(1996)
J Biol Chem
, vol.271
, pp. 15498-503
-
-
Barr, D.P.1
Gunther, M.R.2
Deterding, L.J.3
Tomer, K.B.4
Mason, R.P.5
-
4
-
-
67749107941
-
Antioxidant effects of epicatechin on the hippocampal toxicity caused by amyloid-beta 25-35 in rats
-
Cuevas E, Limon D, Perez-Severiano F, Diaz A, Ortega L, Zenteno E, Guevara J (2009) Antioxidant effects of epicatechin on the hippocampal toxicity caused by amyloid-beta 25-35 in rats. Eur J Pharmacol 616:122-7
-
(2009)
Eur J Pharmacol
, vol.616
, pp. 122-7
-
-
Cuevas, E.1
Limon, D.2
Perez-Severiano, F.3
Diaz, A.4
Ortega, L.5
Zenteno, E.6
Guevara, J.7
-
5
-
-
0037096194
-
Decreased activity of the antioxidant heme oxygenase enzyme: Implications in ischemia and in Alzheimer's disease
-
Doré S (2002) Decreased activity of the antioxidant heme oxygenase enzyme: implications in ischemia and in Alzheimer's disease. Free Radic Biol Med 32:1276-82
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 1276-82
-
-
Doré, S.1
-
6
-
-
0033515043
-
Bilirubin, formed by activation of heme oxygenase-2, protects neurons against oxidative stress injury
-
Doré S, Takahashi M, Ferris CD, Hester LD, Guastella D, Snyder SH (1999) Bilirubin, formed by activation of heme oxygenase-2, protects neurons against oxidative stress injury. Proc Natl Acad Sci USA 96:2445-50
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 2445-50
-
-
Doré, S.1
Takahashi, M.2
Ferris, C.D.3
Hester, L.D.4
Guastella, D.5
Snyder, S.H.6
-
7
-
-
0027306056
-
Vasodilatory effects of flavonoids in rat aortic smooth muscle. Structure-activity relationships
-
Duarte J, Perez Vizcaino F, Utrilla P, Jimenez J, Tamargo J, Zarzuelo A (1993) Vasodilatory effects of flavonoids in rat aortic smooth muscle. Structure-activity relationships. Gen Pharmacol 24:857-62
-
(1993)
Gen Pharmacol
, vol.24
, pp. 857-62
-
-
Duarte, J.1
Perez Vizcaino, F.2
Utrilla, P.3
Jimenez, J.4
Tamargo, J.5
Zarzuelo, A.6
-
8
-
-
2942516022
-
Flavonoid-rich dark chocolate improves endothelial function and increases plasma epicatechin concentrations in healthy adults
-
Engler MB, Engler MM, Chen CY, Malloy MJ, Browne A, Chiu EY, Kwak HK, Milbury P, Paul SM, Blumberg J, Mietus-Snyder ML (2004) Flavonoid-rich dark chocolate improves endothelial function and increases plasma epicatechin concentrations in healthy adults. J Am Coll Nutr 23:197-204
-
(2004)
J Am Coll Nutr
, vol.23
, pp. 197-204
-
-
Engler, M.B.1
Engler, M.M.2
Chen, C.Y.3
Malloy, M.J.4
Browne, A.5
Chiu, E.Y.6
Kwak, H.K.7
Milbury, P.8
Paul, S.M.9
Blumberg, J.10
Mietus-Snyder, M.L.11
-
10
-
-
14644432404
-
Epicatechin and catechin in cocoa inhibit amyloid beta protein induced apoptosis
-
Heo HJ, Lee CY (2005) Epicatechin and catechin in cocoa inhibit amyloid beta protein induced apoptosis. J Agric Food Chem 53:1445-8
-
(2005)
J Agric Food Chem
, vol.53
, pp. 1445-8
-
-
Heo, H.J.1
Lee, C.Y.2
-
11
-
-
0037155806
-
Gene transfection of H25A mutant heme oxyge-nase-1 protects cells against hydroperoxide-induced cytotoxicity
-
Hori R, Kashiba M, Toma T, Yachie A, Goda N, Makino N, Soejima A, Nagasawa T, Nakabayashi K, Suematsu M (2002) Gene transfection of H25A mutant heme oxyge-nase-1 protects cells against hydroperoxide-induced cytotoxicity. J Biol Chem 277:10712-8
-
(2002)
J Biol Chem
, vol.277
, pp. 10712-8
-
-
Hori, R.1
Kashiba, M.2
Toma, T.3
Yachie, A.4
Goda, N.5
Makino, N.6
Soejima, A.7
Nagasawa, T.8
Nakabayashi, K.9
Suematsu, M.10
-
12
-
-
10744230015
-
2
-
2. Mol Cell Biol 24:36-45
-
(2004)
Mol Cell Biol
, vol.24
, pp. 36-45
-
-
Itoh, K.1
Mochizuki, M.2
Ishii, Y.3
Ishii, T.4
Shibata, T.5
Kawamoto, Y.6
Kelly, V.7
Sekizawa, K.8
Uchida, K.9
Yamamoto, M.10
-
13
-
-
0033862093
-
Effects of cocoa extracts on endothelium-dependent relaxation
-
Karim M, McCormick K, Kappagoda CT (2000) Effects of cocoa extracts on endothelium-dependent relaxation. J Nutr 130:2105S-8S
-
(2000)
J Nutr
, vol.130
-
-
Karim, M.1
McCormick, K.2
Kappagoda, C.T.3
-
14
-
-
22544454485
-
Catalytically inactive heme oxygenase-2 mutant is cytoprotective
-
Kim YS, Doré S (2005) Catalytically inactive heme oxygenase-2 mutant is cytoprotective. Free Radic Biol Med 39:558-64
-
(2005)
Free Radic Biol Med
, vol.39
, pp. 558-64
-
-
Kim, Y.S.1
Doré, S.2
-
15
-
-
4444326084
-
Protective effect of green tea polyphenol EGCG against neuronal damage and brain edema after unilateral cerebral ischemia in gerbils
-
Lee H, Bae JH, Lee SR (2004) Protective effect of green tea polyphenol EGCG against neuronal damage and brain edema after unilateral cerebral ischemia in gerbils. J Neurosci Res 77:892-900
-
(2004)
J Neurosci Res
, vol.77
, pp. 892-900
-
-
Lee, H.1
Bae, J.H.2
Lee, S.R.3
-
16
-
-
0034733810
-
Protective effects of the green tea polyphenol (-)-epigallocatechin gallate against hippocampal neuronal damage after transient global ischemia in gerbils
-
Lee S, Suh S, Kim S (2000) Protective effects of the green tea polyphenol (-)-epigallocatechin gallate against hippocampal neuronal damage after transient global ischemia in gerbils. Neurosci Lett 287:191-4
-
(2000)
Neurosci Lett
, vol.287
, pp. 191-4
-
-
Lee, S.1
Suh, S.2
Kim, S.3
-
17
-
-
49849099361
-
Heme oxygenase-1 and the vascular bed: From molecular mechanisms to therapeutic opportunities
-
Loboda A, Jazwa A, Grochot-Przeczek A, Rutkowski AJ, Cisowski J, Agarwal A, Jozkowicz A, Dulak J (2008) Heme oxygenase-1 and the vascular bed: from molecular mechanisms to therapeutic opportunities. Antioxid Redox Signal 10:1767-812
-
(2008)
Antioxid Redox Signal
, vol.10
, pp. 1767-812
-
-
Loboda, A.1
Jazwa, A.2
Grochot-Przeczek, A.3
Rutkowski, A.J.4
Cisowski, J.5
Agarwal, A.6
Jozkowicz, A.7
Dulak, J.8
-
18
-
-
11044228866
-
In vitro antioxidative activity of (-)-epicatechin glucuronide metabolites present in human and rat plasma
-
Natsume M, Osakabe N, Yasuda A, Baba S, Tokunaga T, Kondo K, Osawa T, Terao J (2004) In vitro antioxidative activity of (-)-epicatechin glucuronide metabolites present in human and rat plasma. Free Radic Res 38:1341-8
-
(2004)
Free Radic Res
, vol.38
, pp. 1341-8
-
-
Natsume, M.1
Osakabe, N.2
Yasuda, A.3
Baba, S.4
Tokunaga, T.5
Kondo, K.6
Osawa, T.7
Terao, J.8
-
19
-
-
0030886381
-
Heme oxygenase 1 is required for mammalian iron reutilization
-
Poss KD, Tonegawa S (1997) Heme oxygenase 1 is required for mammalian iron reutilization. Proc Natl Acad Sci USA 94:10919-24
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 10919-24
-
-
Poss, K.D.1
Tonegawa, S.2
-
20
-
-
31444447800
-
Activation of the Keap1/Nrf2 pathway for neuroprotection by electrophi-lic [correction of electrophillic] phase II inducers
-
Satoh T, Okamoto SI, Cui J, Watanabe Y, Furuta K, Suzuki M, Tohyama K, Lipton SA (2006) Activation of the Keap1/Nrf2 pathway for neuroprotection by electrophi-lic [correction of electrophillic] phase II inducers. Proc Natl Acad Sci USA 103:768-73
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 768-73
-
-
Satoh, T.1
Okamoto, S.I.2
Cui, J.3
Watanabe, Y.4
Furuta, K.5
Suzuki, M.6
Tohyama, K.7
Lipton, S.A.8
-
21
-
-
32244437985
-
(-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans
-
Schroeter H, Heiss C, Balzer J, Kleinbongard P, Keen CL, Hollenberg NK, Sies H, Kwik-Uribe C, Schmitz HH, Kelm M (2006) (-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans. Proc Natl Acad Sci USA 103:1024-9
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 1024-9
-
-
Schroeter, H.1
Heiss, C.2
Balzer, J.3
Kleinbongard, P.4
Keen, C.L.5
Hollenberg, N.K.6
Sies, H.7
Kwik-Uribe, C.8
Schmitz, H.H.9
Kelm, M.10
-
22
-
-
24644489772
-
Cerebroprotective effect of Korean ginseng tea against global and focal models of ischemia in rats
-
Shah ZA, Gilani RA, Sharma P, Vohora SB (2005) Cerebroprotective effect of Korean ginseng tea against global and focal models of ischemia in rats. J Ethno-pharmacol 101:299-307
-
(2005)
J Ethno-pharmacol
, vol.101
, pp. 299-307
-
-
Shah, Z.A.1
Gilani, R.A.2
Sharma, P.3
Vohora, S.B.4
-
23
-
-
34249990013
-
Role of reactive oxygen species in modulation of Nrf2 following ischemic reperfusion injury
-
Shah ZA, Li RC, Thimmulappa RK, Kensler TW, Yamamoto M, Biswal S, Dore S (2007) Role of reactive oxygen species in modulation of Nrf2 following ischemic reperfusion injury. Neuroscience 147:53-9
-
(2007)
Neuroscience
, vol.147
, pp. 53-9
-
-
Shah, Z.A.1
Li, R.C.2
Thimmulappa, R.K.3
Kensler, T.W.4
Yamamoto, M.5
Biswal, S.6
Dore, S.7
-
24
-
-
33745745265
-
Use of an optimized transient occlusion of the middle cerebral artery protocol for the mouse stroke model
-
Shah ZA, Namiranian K, Klaus J, Kibler K, Dore S (2006) Use of an optimized transient occlusion of the middle cerebral artery protocol for the mouse stroke model. J Stroke Cerebrovasc Dis 15:133-8
-
(2006)
J Stroke Cerebrovasc Dis
, vol.15
, pp. 133-8
-
-
Shah, Z.A.1
Namiranian, K.2
Klaus, J.3
Kibler, K.4
Dore, S.5
-
25
-
-
27744438478
-
A small-molecule-inducible Nrf2-mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo
-
Shih AY, Li P, Murphy TH (2005) A small-molecule-inducible Nrf2-mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo. J Neurosci 25:10321-35
-
(2005)
J Neurosci
, vol.25
, pp. 10321-35
-
-
Shih, A.Y.1
Li, P.2
Murphy, T.H.3
-
26
-
-
33644878337
-
Polyphenol amento-flavone affords neuroprotection against neonatal hypoxic-ischemic brain damage via multiple mechanisms
-
Shin DH, Bae YC, Kim-Han JS, Lee JH, Choi IY, Son KH, Kang SS, Kim WK, Han BH (2006) Polyphenol amento-flavone affords neuroprotection against neonatal hypoxic-ischemic brain damage via multiple mechanisms. J Neurochem 96:561-72
-
(2006)
J Neurochem
, vol.96
, pp. 561-72
-
-
Shin, D.H.1
Bae, Y.C.2
Kim-Han, J.S.3
Lee, J.H.4
Choi, I.Y.5
Son, K.H.6
Kang, S.S.7
Kim, W.K.8
Han, B.H.9
-
27
-
-
20344382855
-
Polyphenols in cerebral ischemia: Novel targets for neuroprotection
-
Simonyi A, Wang Q, Miller RL, Yusof M, Shelat PB, Sun AY, Sun GY (2005) Polyphenols in cerebral ischemia: novel targets for neuroprotection. Mol Neurobiol 31:135-47
-
(2005)
Mol Neurobiol
, vol.31
, pp. 135-47
-
-
Simonyi, A.1
Wang, Q.2
Miller, R.L.3
Yusof, M.4
Shelat, P.B.5
Sun, A.Y.6
Sun, G.Y.7
-
28
-
-
0034943173
-
Recommendations for clinical trial evaluation of acute stroke therapies
-
Stroke Therapy Academic Industry Roundtable
-
Stroke Therapy Academic Industry Roundtable (2001) Recommendations for clinical trial evaluation of acute stroke therapies. Stroke 32:1598-606
-
(2001)
Stroke
, vol.32
, pp. 1598-606
-
-
-
29
-
-
34249805083
-
Plant-derived flavanol (-)epicatechin enhances angiogenesis and retention of spatial memory in mice
-
van Praag H, Lucero MJ, Yeo GW, Stecker K, Heivand N, Zhao C, Yip E, Afanador M, Schroeter H, Hammerstone J, Gage FH (2007) Plant-derived flavanol (-)epicatechin enhances angiogenesis and retention of spatial memory in mice. J Neurosci 27:5869-78
-
(2007)
J Neurosci
, vol.27
, pp. 5869-78
-
-
Van Praag, H.1
Lucero, M.J.2
Yeo, G.W.3
Stecker, K.4
Heivand, N.5
Zhao, C.6
Yip, E.7
Afanador, M.8
Schroeter, H.9
Hammerstone, J.10
Gage, F.H.11
-
30
-
-
2142766831
-
Delayed treatment of ischemia/reperfusion brain injury: Extended therapeutic window with the proteosome inhibitor MLN519
-
Williams AJ, Berti R, Dave JR, Elliot PJ, Adams J, Tortella FC (2004) Delayed treatment of ischemia/reperfusion brain injury: extended therapeutic window with the proteosome inhibitor MLN519. Stroke 35:1186-91
-
(2004)
Stroke
, vol.35
, pp. 1186-91
-
-
Williams, A.J.1
Berti, R.2
Dave, J.R.3
Elliot, P.J.4
Adams, J.5
Tortella, F.C.6
-
31
-
-
0037215550
-
Delayed treatment with MLN519 reduces infarction and associated neurologic deficit caused by focal ischemic brain injury in rats via antiinflammatory mechanisms involving nuclear fac
-
tor-kappaB activation, gliosis, and leukocyte infiltration
-
Williams AJ, Hale SL, Moffett JR, Dave JR, Elliott PJ, Adams J, Tortella FC (2003) Delayed treatment with MLN519 reduces infarction and associated neurologic deficit caused by focal ischemic brain injury in rats via antiinflammatory mechanisms involving nuclear fac-tor-kappaB activation, gliosis, and leukocyte infiltration. J Cereb Blood Flow Metab 23:75-87
-
(2003)
J Cereb Blood Flow Metab
, vol.23
, pp. 75-87
-
-
Williams, A.J.1
Hale, S.L.2
Moffett, J.R.3
Dave, J.R.4
Elliott, P.J.5
Adams, J.6
Tortella, F.C.7
-
32
-
-
33646588319
-
Extended therapeutic window and functional recovery after intraarterial administration of neuregulin-1 after focal ischemic stroke
-
Xu Z, Croslan DR, Harris AE, Ford GD, Ford BD (2006) Extended therapeutic window and functional recovery after intraarterial administration of neuregulin-1 after focal ischemic stroke. J Cereb Blood Flow Metab 26:527-35
-
(2006)
J Cereb Blood Flow Metab
, vol.26
, pp. 527-35
-
-
Xu, Z.1
Croslan, D.R.2
Harris, A.E.3
Ford, G.D.4
Ford, B.D.5
-
33
-
-
70349730056
-
Low doses of carbon monoxide protect against experimental focal brain ischemia
-
Zeynalov E, Dore S (2009) Low doses of carbon monoxide protect against experimental focal brain ischemia. Neurotox Res 15:133-7
-
(2009)
Neurotox Res
, vol.15
, pp. 133-7
-
-
Zeynalov, E.1
Dore, S.2
-
34
-
-
29244479186
-
Sulfor-aphane reduces infarct volume following focal cerebral ischemia in rodents
-
Zhao J, Kobori N, Aronowski J, Dash PK (2006) Sulfor-aphane reduces infarct volume following focal cerebral ischemia in rodents. Neurosci Lett 393:108-12
-
(2006)
Neurosci Lett
, vol.393
, pp. 108-12
-
-
Zhao, J.1
Kobori, N.2
Aronowski, J.3
Dash, P.K.4
|