Epicatechin induces NF-κB, activator protein-1 (AP-1) and nuclear transcription factor erythroid 2p45-related factor-2 (Nrf2) via phosphatidylinositol-3-kinase/protein kinase B (PI3K/AKT) and extracellular regulated kinase (ERK) signalling in HepG2 cells

British Journal of Nutrition

Volumn 103, Issue 2, 2010, Pages 168-179

  Granado Serrano, Ana Belén ^a   Martín, María Angeles ^a   Haegeman, Guy ^b   Goya, Luis ^a   Bravo, Laura ^a   Ramos, Sonia ^a  

^a INSTITUTO DEL FRÍO CSIC   (Spain)

^b GHENT UNIVERSITY   (Belgium)

Author keywords

Activator protein 1; Epicatechin; NF B signalling; Nuclear factor erythroid 2p45 related factor 2

Indexed keywords

EPICATECHIN; I KAPPA B KINASE; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN C JUN; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NRF2; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CATECHIN; FLAVONOID; NFE2L2 PROTEIN, HUMAN;

ARTICLE; BIOLOGICAL ACTIVITY; CELL PROLIFERATION; CELL STRAIN HEPG2; CELL SURVIVAL; CONTROLLED STUDY; HUMAN; HUMAN CELL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION; BIOSYNTHESIS; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENETICS; KINETICS; METABOLISM; OLIGONUCLEOTIDE PROBE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASES; CATECHIN; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVONOIDS; HEP G2 CELLS; HUMANS; KINETICS; NF-E2-RELATED FACTOR 2; NF-KAPPA B; OLIGONUCLEOTIDE PROBES; PROTO-ONCOGENE PROTEINS C-AKT; TRANSCRIPTION FACTOR AP-1;

EID: 75549090203     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114509991747     Document Type: Article

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