The PI3K/Akt pathway is involved in procyanidin-mediated suppression of human colorectal cancer cell growth

Molecular Carcinogenesis

Volumn 55, Issue 12, 2016, Pages 2196-2209

  Choy, Ying Yng ^a   Fraga, Magdalena ^a   Mackenzie, Gerardo G ^b   Waterhouse, Andrew L ^a   Cremonini, Eleonora ^a   Oteiza, Patricia I ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Stony Brook Medicine   (United States)

Author keywords

apoptosis; autophagy; cell cycle arrest; proanthocyanidin

Indexed keywords

CASPASE 3; CASPASE 9; CYTOCHROME C; DNA; EPICATECHIN; MONOMER; PHOSPHATIDYLINOSITOL 3 KINASE; PROCYANIDIN; PROTEIN KINASE B; ANTINEOPLASTIC AGENT; ANTIOXIDANT; BIFLAVONOID; CATECHIN; PROANTHOCYANIDIN;

APOPTOSIS; ARTICLE; AUTOPHAGY; CACO 2 CELL LINE; CANCER INHIBITION; CELL DEATH; CELL VIABILITY; COLORECTAL CANCER; COLORECTAL CANCER CELL LINE; CONTROLLED STUDY; CYTOSOL; DNA FRAGMENTATION; ENZYME ACTIVATION; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN SECRETION; UPREGULATION; CACO-2 CELL LINE; CELL CYCLE CHECKPOINT; CELL PROLIFERATION; COLON; COLORECTAL TUMOR; DRUG EFFECTS; METABOLISM; RECTUM; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; ANTIOXIDANTS; APOPTOSIS; BIFLAVONOIDS; CACO-2 CELLS; CATECHIN; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL PROLIFERATION; COLON; COLORECTAL NEOPLASMS; HUMANS; PHOSPHATIDYLINOSITOL 3-KINASES; PROANTHOCYANIDINS; PROTO-ONCOGENE PROTEINS C-AKT; RECTUM; SIGNAL TRANSDUCTION;

EID: 84955083741     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.22461     Document Type: Article

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