Determinants of thermostability in the cytochrome P450 fold

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1866, Issue 1, 2018, Pages 97-115

  Harris, Kurt L ^a   Thomson, Raine E S ^a   Strohmaier, Silja J ^a   Gumulya, Yosephine ^a   Gillam, Elizabeth M J ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Biocatalysis; Cytochrome P450; Directed evolution; Extremophile; Thermostability

Indexed keywords

2 OXOACID; CYSTEINE; CYTOCHROME P450; CYTOCHROME P450 119A2; CYTOCHROME P450 175A1; CYTOCHROME P450 231A2; CYTOCHROME P450 BM3; FERREDOXIN; OXIDOREDUCTASE; THREONINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENVIRONMENT; ENZYME STABILITY; MESOPHILIC BACTERIUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN STRUCTURE; REVIEW; SURFACE PROPERTY; TEMPERATURE; THERMOPHILIC BACTERIUM; THERMOSTABILITY; ALPHA HELIX; ANIMAL; ARCHAEON; BACTERIUM; BETA SHEET; BIOCATALYSIS; CHEMISTRY; ENZYME SPECIFICITY; ENZYMOLOGY; GENE EXPRESSION; GENETICS; HUMAN; MOLECULAR MODEL; PROCEDURES; PROTEIN FOLDING; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; ARCHAEA; BACTERIA; BIOCATALYSIS; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME STABILITY; GENE EXPRESSION; HUMANS; MODELS, MOLECULAR; PROTEIN CONFORMATION, ALPHA-HELICAL; PROTEIN CONFORMATION, BETA-STRAND; PROTEIN ENGINEERING; PROTEIN FOLDING; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

EID: 85029760233     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2017.08.003     Document Type: Review

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