Understanding thermostability in cytochrome P450 by combinatorial mutagenesis

Protein Science

Volumn 10, Issue 1, 2001, Pages 161-168

  Maves, Shelley A ^a   Sligar, Stephen G ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Cytochrome P450; Electrostatic interactions; Random mutagenesis; Salt links; Thermostability

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 119; CYTOCHROME P450 ISOENZYME; MUTANT PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CROSS LINKING; DIFFERENTIAL SCANNING CALORIMETRY; ENZYME STABILITY; MELTING POINT; MOLECULAR INTERACTION; MUTAGENESIS; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; STEROIDOGENESIS; SULFOLOBUS SOLFATARICUS; THERMOSTABILITY; XENOBIOTIC METABOLISM;

CYTOCHROME P-450 ENZYME SYSTEM; ENZYME STABILITY; MODELS, MOLECULAR; MUTAGENESIS; PROTEIN ENGINEERING; SULFOLOBUS; THERMODYNAMICS;

BACTERIA (MICROORGANISMS); SULFOLOBUS SOLFATARICUS;

EID: 0035100923     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.17601     Document Type: Article

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