Functional evolution and structural conservation in chimeric cytochromes P450: Calibrating a structure-guided approach

Chemistry and Biology

Volumn 11, Issue 3, 2004, Pages 309-318

  Otey, Christopher R ^a   Silberg, Jonathan J ^b   Voigt, Christopher A ^c   Endelman, Jeffrey B ^a   Bandara, Geethani ^b   Arnold, Frances H ^a,b  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b California Institute of Technology   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; HEME; HYBRID PROTEIN; MIXED FUNCTION OXIDASE; OXIDOREDUCTASE; PEROXIDASE; PEROXYGENASE;

ARTICLE; BACILLUS; CALIBRATION; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME STABILITY; ENZYMOLOGY; GENE LIBRARY; GENETICS; METABOLISM; MOLECULAR EVOLUTION; MUTATION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN TERTIARY STRUCTURE; STRUCTURAL HOMOLOGY; TEMPERATURE;

BACILLUS; CALIBRATION; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME STABILITY; EVOLUTION, MOLECULAR; GENE LIBRARY; HEME; MIXED FUNCTION OXYGENASES; MODELS, MOLECULAR; MUTATION; OXIDOREDUCTASES; PEROXIDASE; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; STRUCTURAL HOMOLOGY, PROTEIN; TEMPERATURE;

EID: 4043109994     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2004.02.018     Document Type: Article

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