Highly Efficient CYP167A1 (EpoK) dependent Epothilone B Formation and Production of 7-Ketone Epothilone D as a New Epothilone Derivative

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Kern, Fredy ^a   Dier, Tobias K F ^a   Khatri, Yogan ^a   Ewen, Kerstin M ^a   Jacquot, Jean Pierre ^b   Volmer, Dietrich A ^a   Bernhardt, Rita ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b UNIVERSITÉ DE LORRAINE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BACTERIAL PROTEIN; CYTOCHROME P450; EPOTHILONE DERIVATIVE; FERREDOXIN; KETONE; RECOMBINANT PROTEIN;

BIOCATALYSIS; BIOSYNTHESIS; CHEMISTRY; ELECTRON; ELECTRON TRANSPORT; ENZYMOLOGY; ESCHERICHIA COLI; GENE EXPRESSION; GENETICS; METABOLISM; MOLECULAR CLONING; MYXOCOCCALES; OXIDATION REDUCTION REACTION; PHYLOGENY; PROTEIN ENGINEERING;

ANTINEOPLASTIC AGENTS; BACTERIAL PROTEINS; BIOCATALYSIS; CLONING, MOLECULAR; CYTOCHROME P-450 ENZYME SYSTEM; ELECTRON TRANSPORT; ELECTRONS; EPOTHILONES; ESCHERICHIA COLI; FERREDOXINS; GENE EXPRESSION; KETONES; MYXOCOCCALES; OXIDATION-REDUCTION; PHYLOGENY; PROTEIN ENGINEERING; RECOMBINANT PROTEINS;

EID: 84943574826     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep14881     Document Type: Article

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