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Volumn 6, Issue , 2017, Pages

Recent insights into the implications of metabolism in plasmacytoid dendritic cell innate functions: Potential ways to control these functions

Author keywords

Cholesterol; Fatty acid; Glycolysis; Immunometabolism; LXR; Plasmacytoid dendritic cells; PPAR; Type I interferon

Indexed keywords

HIGH MOBILITY GROUP B1 PROTEIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INFLUENZA VACCINE; INTERFERON; INTERLEUKIN 6; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; TRANSFORMING GROWTH FACTOR BETA;

EID: 85019568379     PISSN: 20461402     EISSN: 1759796X     Source Type: Journal    
DOI: 10.12688/f1000research.11332.1     Document Type: Review
Times cited : (21)

References (105)
  • 1
    • 84960399221 scopus 로고    scopus 로고
    • Immunometabolism governs dendritic cell and macrophage function
    • 26694970, 4710204
    • O'Neill LA Pearce EJ: Immunometabolism governs dendritic cell and macrophage function. J Exp Med. 2016;213(1):15-23. 26694970 10.1084/jem.20151570 4710204
    • (2016) J Exp Med , vol.213 , Issue.1 , pp. 15-23
    • O'Neill, L.A.1    Pearce, E.J.2
  • 2
    • 84978148203 scopus 로고    scopus 로고
    • A guide to immunometabolism for immunologists
    • 27396447, 5001910
    • O'Neill LA Kishton RJ Rathmell J: A guide to immunometabolism for immunologists. Nat Rev Immunol. 2016;16(9):553-565. 27396447 10.1038/nri.2016.70 5001910
    • (2016) Nat Rev Immunol , vol.16 , Issue.9 , pp. 553-565
    • O'Neill, L.A.1    Kishton, R.J.2    Rathmell, J.3
  • 3
    • 84925546388 scopus 로고    scopus 로고
    • Dendritic cell metabolism
    • 25534620, 4495583
    • Pearce EJ Everts B: Dendritic cell metabolism. Nat Rev Immunol. 2015;15(1):18-29. 25534620 10.1038/nri3771 4495583
    • (2015) Nat Rev Immunol , vol.15 , Issue.1 , pp. 18-29
    • Pearce, E.J.1    Everts, B.2
  • 4
    • 84962030790 scopus 로고    scopus 로고
    • Cutting Edge: Critical Role of Glycolysis in Human Plasmacytoid Dendritic Cell Antiviral Responses
    • 26826244, 4761472
    • Bajwa G DeBerardinis RJ Shao B: Cutting Edge: Critical Role of Glycolysis in Human Plasmacytoid Dendritic Cell Antiviral Responses. J Immunol. 2016;196(5):2004-2009. 26826244 10.4049/jimmunol.1501557 4761472
    • (2016) J Immunol , vol.196 , Issue.5 , pp. 2004-2009
    • Bajwa, G.1    DeBerardinis, R.J.2    Shao, B.3
  • 5
    • 84975044477 scopus 로고    scopus 로고
    • Type 1 Interferons Induce Changes in Core Metabolism that Are Critical for Immune Function
    • 27332732
    • Wu D Sanin DE Everts B: Type 1 Interferons Induce Changes in Core Metabolism that Are Critical for Immune Function. Immunity. 2016;44(6):1325-1336. 27332732 10.1016/j.immuni.2016.06.006
    • (2016) Immunity , vol.44 , Issue.6 , pp. 1325-1336
    • Wu, D.1    Sanin, D.E.2    Everts, B.3
  • 6
    • 84959290932 scopus 로고    scopus 로고
    • The anti-inflammatory effects of platelet-derived microparticles in human plasmacytoid dendritic cells involve liver X receptor activation
    • 26635040, 4815731
    • Ceroi A Delettre FA Marotel C: The anti-inflammatory effects of platelet-derived microparticles in human plasmacytoid dendritic cells involve liver X receptor activation. Haematologica. 2016;101(3):e72-76. 26635040 10.3324/haematol.2015.135459 4815731
    • (2016) Haematologica , vol.101 , Issue.3
    • Ceroi, A.1    Delettre, F.A.2    Marotel, C.3
  • 7
    • 84937967684 scopus 로고    scopus 로고
    • The multifaceted biology of plasmacytoid dendritic cells
    • 26160613, 4808588
    • Swiecki M Colonna M: The multifaceted biology of plasmacytoid dendritic cells. Nat Rev Immunol. 2015;15(8):471-485. 26160613 10.1038/nri3865 4808588
    • (2015) Nat Rev Immunol , vol.15 , Issue.8 , pp. 471-485
    • Swiecki, M.1    Colonna, M.2
  • 8
    • 84942585419 scopus 로고    scopus 로고
    • Regulation of innate immune cell function by mTOR
    • 26403194
    • Weichhart T Hengstschläger M Linke M: Regulation of innate immune cell function by mTOR. Nat Rev Immunol. 2015;15(10):599-614. 26403194 10.1038/nri3901
    • (2015) Nat Rev Immunol , vol.15 , Issue.10 , pp. 599-614
    • Weichhart, T.1    Hengstschläger, M.2    Linke, M.3
  • 9
    • 67650351923 scopus 로고    scopus 로고
    • + Tregs to TH17-like cells in tumor-draining lymph nodes
    • 19366986, 2699232
    • Sharma MD Hou DY Liu Y: Indoleamine 2,3-dioxygenase controls conversion of Foxp3 + Tregs to TH17-like cells in tumor-draining lymph nodes. Blood. 2009;113(24):6102-6111. 19366986 10.1182/blood-2008-12-195354 2699232
    • (2009) Blood , vol.113 , Issue.24 , pp. 6102-6111
    • Sharma, M.D.1    Hou, D.Y.2    Liu, Y.3
  • 10
    • 84876758617 scopus 로고    scopus 로고
    • Metabolic pathways in immune cell activation and quiescence
    • 23601682, 3654249
    • Pearce EL Pearce EJ: Metabolic pathways in immune cell activation and quiescence. Immunity. 2013;38(4):633-643. 23601682 10.1016/j.immuni.2013.04.005 3654249
    • (2013) Immunity , vol.38 , Issue.4 , pp. 633-643
    • Pearce, E.L.1    Pearce, E.J.2
  • 11
    • 84921926094 scopus 로고    scopus 로고
    • Energizing Genetics and Epi-genetics: Role in the Regulation of Mitochondrial Function
    • 25646072, 4311388
    • Audano M Ferrari A Fiorino E: Energizing Genetics and Epi-genetics: Role in the Regulation of Mitochondrial Function. Curr Genomics. 2014;15(6):436-456. 25646072 10.2174/138920291506150106151119 4311388
    • (2014) Curr Genomics , vol.15 , Issue.6 , pp. 436-456
    • Audano, M.1    Ferrari, A.2    Fiorino, E.3
  • 12
    • 84979891789 scopus 로고    scopus 로고
    • Metabolic Factors that Contribute to Lupus Pathogenesis
    • 27480903, 5278665
    • Li W Sivakumar R Titov AA: Metabolic Factors that Contribute to Lupus Pathogenesis. Crit Rev Immunol. 2016;36(1):75-98. 27480903 10.1615/CritRevImmunol.2016017164 5278665
    • (2016) Crit Rev Immunol , vol.36 , Issue.1 , pp. 75-98
    • Li, W.1    Sivakumar, R.2    Titov, A.A.3
  • 13
    • 84905107360 scopus 로고    scopus 로고
    • Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny
    • 25033907, 4638219
    • Guilliams M Ginhoux F Jakubzick C: Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny. Nat Rev Immunol. 2014;14(8):571-578. 25033907 10.1038/nri3712 4638219
    • (2014) Nat Rev Immunol , vol.14 , Issue.8 , pp. 571-578
    • Guilliams, M.1    Ginhoux, F.2    Jakubzick, C.3
  • 14
    • 0032773794 scopus 로고    scopus 로고
    • Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon
    • 10426316
    • Cella M Jarrossay D Facchetti F: Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon. Nat Med. 1999;5(8):919-923. 10426316 10.1038/11360
    • (1999) Nat Med , vol.5 , Issue.8 , pp. 919-923
    • Cella, M.1    Jarrossay, D.2    Facchetti, F.3
  • 15
    • 0033546053 scopus 로고    scopus 로고
    • The nature of the principal type 1 interferon-producing cells in human blood
    • 10364556
    • Siegal FP Kadowaki N Shodell M: The nature of the principal type 1 interferon-producing cells in human blood. Science. 1999;284(5421):1835-1837. 10364556 10.1126/science.284.5421.1835
    • (1999) Science , vol.284 , Issue.5421 , pp. 1835-1837
    • Siegal, F.P.1    Kadowaki, N.2    Shodell, M.3
  • 16
    • 0035202483 scopus 로고    scopus 로고
    • Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology
    • 11713464
    • Asselin-Paturel C Boonstra A Dalod M: Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology. Nat Immunol. 2001;2(12):1144-1150. 11713464 10.1038/ni736
    • (2001) Nat Immunol , vol.2 , Issue.12 , pp. 1144-1150
    • Asselin-Paturel, C.1    Boonstra, A.2    Dalod, M.3
  • 17
    • 0035887505 scopus 로고    scopus 로고
    • + cells in mouse lymph nodes and spleen display characteristics of plasmacytoid dendritic cells
    • 11602645, 2193516
    • Nakano H Yanagita M Gunn MD: CD11c +B220 +Gr-1 + cells in mouse lymph nodes and spleen display characteristics of plasmacytoid dendritic cells. J Exp Med. 2001;194(8):1171-1178. 11602645 10.1084/jem.194.8.1171 2193516
    • (2001) J Exp Med , vol.194 , Issue.8 , pp. 1171-1178
    • Nakano, H.1    Yanagita, M.2    Gunn, M.D.3
  • 18
    • 0037108556 scopus 로고    scopus 로고
    • + plasmacytoid dendritic cells develop independently of the T-cell lineage
    • 12351395
    • Ferrero I Held W Wilson A: Mouse CD11c + B220 + Gr1 + plasmacytoid dendritic cells develop independently of the T-cell lineage. Blood. 2002;100(8):2852-2857. 12351395 10.1182/blood-2002-01-0214
    • (2002) Blood , vol.100 , Issue.8 , pp. 2852-2857
    • Ferrero, I.1    Held, W.2    Wilson, A.3
  • 19
    • 0037100317 scopus 로고    scopus 로고
    • + dendritic cells endowed with type 1 interferon production capacity and tolerogenic potential
    • 12091326
    • Martin P Del Hoyo GM Anjuere F: Characterization of a new subpopulation of mouse CD8α + B220 + dendritic cells endowed with type 1 interferon production capacity and tolerogenic potential. Blood. 2002;100(2):383-390. 12091326 10.1182/blood.V100.2.383
    • (2002) Blood , vol.100 , Issue.2 , pp. 383-390
    • Martin, P.1    Del Hoyo, G.M.2    Anjuere, F.3
  • 20
    • 45749120843 scopus 로고    scopus 로고
    • Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling
    • 18218067, 2395256
    • Robbins SH Walzer T Dembélé D: Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling. Genome Biol. 2008;9(1):R17. 18218067 10.1186/gb-2008-9-1-r17 2395256
    • (2008) Genome Biol , vol.9 , Issue.1 , pp. R17
    • Robbins, S.H.1    Walzer, T.2    Dembélé, D.3
  • 21
    • 65249089638 scopus 로고    scopus 로고
    • In vivo analysis of dendritic cell development and homeostasis
    • 19286519, 2803315
    • Liu K Victora GD Schwickert TA: In vivo analysis of dendritic cell development and homeostasis. Science. 2009;324(5925):392-397. 19286519 10.1126/science.1170540 2803315
    • (2009) Science , vol.324 , Issue.5925 , pp. 392-397
    • Liu, K.1    Victora, G.D.2    Schwickert, T.A.3
  • 22
    • 80053620170 scopus 로고    scopus 로고
    • Cell-intrinsic role for IFN-α-STAT1 signals in regulating murine Peyer patch plasmacytoid dendritic cells and conditioning an inflammatory response
    • 21828128, 3193265
    • Li HS Gelbard A Martinez GJ: Cell-intrinsic role for IFN-α-STAT1 signals in regulating murine Peyer patch plasmacytoid dendritic cells and conditioning an inflammatory response. Blood. 2011;118(14):3879-3889. 21828128 10.1182/blood-2011-04-349761 3193265
    • (2011) Blood , vol.118 , Issue.14 , pp. 3879-3889
    • Li, H.S.1    Gelbard, A.2    Martinez, G.J.3
  • 23
    • 81055144329 scopus 로고    scopus 로고
    • CCR6/CCR10-mediated plasmacytoid dendritic cell recruitment to inflamed epithelia after instruction in lymphoid tissues
    • 21937703, 3217401
    • Sisirak V Vey N Vanbervliet B: CCR6/CCR10-mediated plasmacytoid dendritic cell recruitment to inflamed epithelia after instruction in lymphoid tissues. Blood. 2011;118(19):5130-5140. 21937703 10.1182/blood-2010-07-295626 3217401
    • (2011) Blood , vol.118 , Issue.19 , pp. 5130-5140
    • Sisirak, V.1    Vey, N.2    Vanbervliet, B.3
  • 24
    • 3142720367 scopus 로고    scopus 로고
    • Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen
    • 15238608, 2213319
    • de Heer HJ Hammad H Soullié T: Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen. J Exp Med. 2004;200(1):89-98. 15238608 10.1084/jem.20040035 2213319
    • (2004) J Exp Med , vol.200 , Issue.1 , pp. 89-98
    • de Heer, H.J.1    Hammad, H.2    Soullié, T.3
  • 25
    • 55549148718 scopus 로고    scopus 로고
    • Poor allostimulatory function of liver plasmacytoid DC is associated with pro-apoptotic activity, dependent on regulatory T cells
    • 18926588, 2631180
    • Tokita D Sumpter TL Raimondi G: Poor allostimulatory function of liver plasmacytoid DC is associated with pro-apoptotic activity, dependent on regulatory T cells. J Hepatol. 2008;49(6):1008-1018. 18926588 10.1016/j.jhep.2008.07.028 2631180
    • (2008) J Hepatol , vol.49 , Issue.6 , pp. 1008-1018
    • Tokita, D.1    Sumpter, T.L.2    Raimondi, G.3
  • 26
    • 77957108257 scopus 로고    scopus 로고
    • Tolerogenic plasmacytoid DC
    • 20821731, 3974856
    • Matta BM Castellaneta A Thomson AW: Tolerogenic plasmacytoid DC. Eur J Immunol. 2010;40(10):2667-2676. 20821731 10.1002/eji.201040839 3974856
    • (2010) Eur J Immunol , vol.40 , Issue.10 , pp. 2667-2676
    • Matta, B.M.1    Castellaneta, A.2    Thomson, A.W.3
  • 27
    • 0038068036 scopus 로고    scopus 로고
    • Murine thymic plasmacytoid dendritic cells
    • 12672067
    • Okada T Lian ZX Naiki M: Murine thymic plasmacytoid dendritic cells. Eur J Immunol. 2003;33(4):1012-1019. 12672067 10.1002/eji.200323616
    • (2003) Eur J Immunol , vol.33 , Issue.4 , pp. 1012-1019
    • Okada, T.1    Lian, Z.X.2    Naiki, M.3
  • 28
    • 63449133991 scopus 로고    scopus 로고
    • Thymus-homing peripheral dendritic cells constitute two of the three major subsets of dendritic cells in the steady-state thymus
    • 19273629, 2699131
    • Li J Park J Foss D: Thymus-homing peripheral dendritic cells constitute two of the three major subsets of dendritic cells in the steady-state thymus. J Exp Med. 2009;206(3):607-622. 19273629 10.1084/jem.20082232 2699131
    • (2009) J Exp Med , vol.206 , Issue.3 , pp. 607-622
    • Li, J.1    Park, J.2    Foss, D.3
  • 29
    • 84858786391 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells transport peripheral antigens to the thymus to promote central tolerance
    • 22444632, 3315699
    • Hadeiba H Lahl K Edalati A: Plasmacytoid dendritic cells transport peripheral antigens to the thymus to promote central tolerance. Immunity. 2012;36(3):438-450. 22444632 10.1016/j.immuni.2012.01.017 3315699
    • (2012) Immunity , vol.36 , Issue.3 , pp. 438-450
    • Hadeiba, H.1    Lahl, K.2    Edalati, A.3
  • 30
    • 20044369873 scopus 로고    scopus 로고
    • Role of ChemR23 in directing the migration of myeloid and plasmacytoid dendritic cells to lymphoid organs and inflamed skin
    • 15728234, 2213064
    • Vermi W Riboldi E Wittamer V: Role of ChemR23 in directing the migration of myeloid and plasmacytoid dendritic cells to lymphoid organs and inflamed skin. J Exp Med. 2005;201(4):509-515. 15728234 10.1084/jem.20041310 2213064
    • (2005) J Exp Med , vol.201 , Issue.4 , pp. 509-515
    • Vermi, W.1    Riboldi, E.2    Wittamer, V.3
  • 31
    • 48749085127 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases
    • 18641647
    • Gilliet M Cao W Liu YJ: Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases. Nat Rev Immunol. 2008;8(8):594-606. 18641647 10.1038/nri2358
    • (2008) Nat Rev Immunol , vol.8 , Issue.8 , pp. 594-606
    • Gilliet, M.1    Cao, W.2    Liu, Y.J.3
  • 32
    • 79953059788 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells: recent progress and open questions
    • 21219184, 4160806
    • Reizis B Bunin A Ghosh HS: Plasmacytoid dendritic cells: recent progress and open questions. Annu Rev Immunol. 2011;29:163-183. 21219184 10.1146/annurev-immunol-031210-101345 4160806
    • (2011) Annu Rev Immunol , vol.29 , pp. 163-183
    • Reizis, B.1    Bunin, A.2    Ghosh, H.S.3
  • 33
    • 84857426963 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells control T-cell response to chronic viral infection
    • 22315415, 3286988
    • Cervantes-Barragan L Lewis KL Firner S: Plasmacytoid dendritic cells control T-cell response to chronic viral infection. Proc Natl Acad Sci U S A. 2012;109(8):3012-3017. 22315415 10.1073/pnas.1117359109 3286988
    • (2012) Proc Natl Acad Sci U S A , vol.109 , Issue.8 , pp. 3012-3017
    • Cervantes-Barragan, L.1    Lewis, K.L.2    Firner, S.3
  • 34
    • 78650178928 scopus 로고    scopus 로고
    • + T cell accrual
    • 21130004, 3588567
    • Swiecki M Gilfillan S Vermi W: Plasmacytoid dendritic cell ablation impacts early interferon responses and antiviral NK and CD8 + T cell accrual. Immunity. 2010;33(6):955-966. 21130004 10.1016/j.immuni.2010.11.020 3588567
    • (2010) Immunity , vol.33 , Issue.6 , pp. 955-966
    • Swiecki, M.1    Gilfillan, S.2    Vermi, W.3
  • 35
    • 84255215466 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells are crucial for the initiation of inflammation and T cell immunity in vivo
    • 22177923
    • Takagi H Fukaya T Eizumi K: Plasmacytoid dendritic cells are crucial for the initiation of inflammation and T cell immunity in vivo. Immunity. 2011;35(6):958-971. 22177923 10.1016/j.immuni.2011.10.014
    • (2011) Immunity , vol.35 , Issue.6 , pp. 958-971
    • Takagi, H.1    Fukaya, T.2    Eizumi, K.3
  • 36
    • 84880010925 scopus 로고    scopus 로고
    • IRF5, IRF8, and IRF7 in human pDCs - the good, the bad, and the insignificant?
    • 23828296
    • Pelka K Latz E: IRF5, IRF8, and IRF7 in human pDCs - the good, the bad, and the insignificant? Eur J Immunol. 2013;43(7):1693-1697. 23828296 10.1002/eji.201343739
    • (2013) Eur J Immunol , vol.43 , Issue.7 , pp. 1693-1697
    • Pelka, K.1    Latz, E.2
  • 37
    • 0035903288 scopus 로고    scopus 로고
    • Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens
    • 11561001, 2195968
    • Kadowaki N Ho S Antonenko S: Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens. J Exp Med. 2001;194(6):863-869. 11561001 10.1084/jem.194.6.863 2195968
    • (2001) J Exp Med , vol.194 , Issue.6 , pp. 863-869
    • Kadowaki, N.1    Ho, S.2    Antonenko, S.3
  • 38
    • 1542317550 scopus 로고    scopus 로고
    • Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
    • 14976261
    • Diebold SS Kaisho T Hemmi H: Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science. 2004;303(5663):1529-1531. 14976261 10.1126/science.1093616
    • (2004) Science , vol.303 , Issue.5663 , pp. 1529-1531
    • Diebold, S.S.1    Kaisho, T.2    Hemmi, H.3
  • 39
    • 23744454577 scopus 로고    scopus 로고
    • TLR signalling and activation of IRFs: revisiting old friends from the NF-kappaB pathway
    • 16006187
    • Moynagh PN: TLR signalling and activation of IRFs: revisiting old friends from the NF-kappaB pathway. Trends Immunol. 2005;26(9):469-476. 16006187 10.1016/j.it.2005.06.009
    • (2005) Trends Immunol , vol.26 , Issue.9 , pp. 469-476
    • Moynagh, P.N.1
  • 40
    • 26844467349 scopus 로고    scopus 로고
    • Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus
    • 16230478, 2213213
    • Barrat FJ Meeker T Gregorio J: Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus. J Exp Med. 2005;202(8):1131-1139. 16230478 10.1084/jem.20050914 2213213
    • (2005) J Exp Med , vol.202 , Issue.8 , pp. 1131-1139
    • Barrat, F.J.1    Meeker, T.2    Gregorio, J.3
  • 41
    • 34948862264 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide
    • 17873860
    • Lande R Gregorio J Facchinetti V: Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide. Nature. 2007;449(7162):564-569. 17873860 10.1038/nature06116
    • (2007) Nature , vol.449 , Issue.7162 , pp. 564-569
    • Lande, R.1    Gregorio, J.2    Facchinetti, V.3
  • 42
    • 69549135324 scopus 로고    scopus 로고
    • Self-RNA-antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8
    • 19703986, 2737167
    • Ganguly D Chamilos G Lande R: Self-RNA-antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8. J Exp Med. 2009;206(9):1983-1994. 19703986 10.1084/jem.20090480 2737167
    • (2009) J Exp Med , vol.206 , Issue.9 , pp. 1983-1994
    • Ganguly, D.1    Chamilos, G.2    Lande, R.3
  • 43
    • 17144404177 scopus 로고    scopus 로고
    • IRF-7 is the master regulator of type-I interferon-dependent immune responses
    • 15800576
    • Honda K Yanai H Negishi H: IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature. 2005;434(7034):772-777. 15800576 10.1038/nature03464
    • (2005) Nature , vol.434 , Issue.7034 , pp. 772-777
    • Honda, K.1    Yanai, H.2    Negishi, H.3
  • 44
    • 39549116503 scopus 로고    scopus 로고
    • PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation
    • 18227218, 2271003
    • Guiducci C Ghirelli C Marloie-Provost MA: PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation. J Exp Med. 2008;205(2):315-322. 18227218 10.1084/jem.20070763 2271003
    • (2008) J Exp Med , vol.205 , Issue.2 , pp. 315-322
    • Guiducci, C.1    Ghirelli, C.2    Marloie-Provost, M.A.3
  • 45
    • 0035871737 scopus 로고    scopus 로고
    • + dendritic cells
    • 11290780
    • Bauer M Redecke V Ellwart JW: Bacterial CpG-DNA triggers activation and maturation of human CD11c -, CD123 + dendritic cells. J Immunol. 2001;166(8):5000-5007. 11290780 10.4049/jimmunol.166.8.5000
    • (2001) J Immunol , vol.166 , Issue.8 , pp. 5000-5007
    • Bauer, M.1    Redecke, V.2    Ellwart, J.W.3
  • 46
    • 70449432794 scopus 로고    scopus 로고
    • Endothelial cell-derived microparticles induce plasmacytoid dendritic cell maturation: potential implications in inflammatory diseases
    • 19648164, 2770960
    • Angelot F Seillès E Biichlé S: Endothelial cell-derived microparticles induce plasmacytoid dendritic cell maturation: potential implications in inflammatory diseases. Haematologica. 2009;94(11):1502-1512. 19648164 10.3324/haematol.2009.010934 2770960
    • (2009) Haematologica , vol.94 , Issue.11 , pp. 1502-1512
    • Angelot, F.1    Seillès, E.2    Biichlé, S.3
  • 47
    • 33645518610 scopus 로고    scopus 로고
    • Upon viral exposure, myeloid and plasmacytoid dendritic cells produce 3 waves of distinct chemokines to recruit immune effectors
    • 16317096, 1895384
    • Piqueras B Connolly J Freitas H: Upon viral exposure, myeloid and plasmacytoid dendritic cells produce 3 waves of distinct chemokines to recruit immune effectors. Blood. 2006;107(7):2613-2618. 16317096 10.1182/blood-2005-07-2965 1895384
    • (2006) Blood , vol.107 , Issue.7 , pp. 2613-2618
    • Piqueras, B.1    Connolly, J.2    Freitas, H.3
  • 48
    • 0037407691 scopus 로고    scopus 로고
    • Activation with CpG-A and CpG-B oligonucleotides reveals two distinct regulatory pathways of type I IFN synthesis in human plasmacytoid dendritic cells
    • 12707322
    • Kerkmann M Rothenfusser S Hornung V: Activation with CpG-A and CpG-B oligonucleotides reveals two distinct regulatory pathways of type I IFN synthesis in human plasmacytoid dendritic cells. J Immunol. 2003;170(9):4465-4474. 12707322 10.4049/jimmunol.170.9.4465
    • (2003) J Immunol , vol.170 , Issue.9 , pp. 4465-4474
    • Kerkmann, M.1    Rothenfusser, S.2    Hornung, V.3
  • 49
    • 34247236200 scopus 로고    scopus 로고
    • Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE
    • 17417641
    • Tian J Avalos AM Mao SY: Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE. Nat Immunol. 2007;8(5):487-496. 17417641 10.1038/ni1457
    • (2007) Nat Immunol , vol.8 , Issue.5 , pp. 487-496
    • Tian, J.1    Avalos, A.M.2    Mao, S.Y.3
  • 50
    • 22544445228 scopus 로고    scopus 로고
    • Requirement of HMGB1 and RAGE for the maturation of human plasmacytoid dendritic cells
    • 15915542
    • Dumitriu IE Baruah P Bianchi ME: Requirement of HMGB1 and RAGE for the maturation of human plasmacytoid dendritic cells. Eur J Immunol. 2005;35(7):2184-2190. 15915542 10.1002/eji.200526066
    • (2005) Eur J Immunol , vol.35 , Issue.7 , pp. 2184-2190
    • Dumitriu, I.E.1    Baruah, P.2    Bianchi, M.E.3
  • 51
    • 4444261780 scopus 로고    scopus 로고
    • HMGB1 is an endogenous immune adjuvant released by necrotic cells
    • 15272298, 1299116
    • Rovere-Querini P Capobianco A Scaffidi P: HMGB1 is an endogenous immune adjuvant released by necrotic cells. EMBO Rep. 2004;5(8):825-830. 15272298 10.1038/sj.embor.7400205 1299116
    • (2004) EMBO Rep , vol.5 , Issue.8 , pp. 825-830
    • Rovere-Querini, P.1    Capobianco, A.2    Scaffidi, P.3
  • 52
    • 79952476762 scopus 로고    scopus 로고
    • Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus
    • 21389264, 3143837
    • Garcia-Romo GS Caielli S Vega B: Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus. Sci Transl Med. 2011;3(73):73ra20. 21389264 10.1126/scitranslmed.3001201 3143837
    • (2011) Sci Transl Med , vol.3 , Issue.73
    • Garcia-Romo, G.S.1    Caielli, S.2    Vega, B.3
  • 53
    • 79952468782 scopus 로고    scopus 로고
    • Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes in systemic lupus erythematosus
    • 21389263, 3399524
    • Lande R Ganguly D Facchinetti V: Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes in systemic lupus erythematosus. Sci Transl Med. 2011;3(73):73ra19. 21389263 10.1126/scitranslmed.3001180 3399524
    • (2011) Sci Transl Med , vol.3 , Issue.73
    • Lande, R.1    Ganguly, D.2    Facchinetti, V.3
  • 54
    • 77956454663 scopus 로고    scopus 로고
    • Platelet CD154 potentiates interferon-alpha secretion by plasmacytoid dendritic cells in systemic lupus erythematosus
    • 20811042
    • Duffau P Seneschal J Nicco C: Platelet CD154 potentiates interferon-alpha secretion by plasmacytoid dendritic cells in systemic lupus erythematosus. Sci Transl Med. 2010;2(47):47ra63. 20811042 10.1126/scitranslmed.3001001
    • (2010) Sci Transl Med , vol.2 , Issue.47 , pp. 47ra63
    • Duffau, P.1    Seneschal, J.2    Nicco, C.3
  • 55
    • 84880923978 scopus 로고    scopus 로고
    • Newly described pattern recognition receptors team up against intracellular pathogens
    • 23846113
    • Broz P Monack DM: Newly described pattern recognition receptors team up against intracellular pathogens. Nat Rev Immunol. 2013;13(8):551-565. 23846113 10.1038/nri3479
    • (2013) Nat Rev Immunol , vol.13 , Issue.8 , pp. 551-565
    • Broz, P.1    Monack, D.M.2
  • 56
    • 79956207599 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells play a major role in apoptotic leukocyte-induced immune modulation
    • 21460208
    • Bonnefoy F Perruche S Couturier M: Plasmacytoid dendritic cells play a major role in apoptotic leukocyte-induced immune modulation. J Immunol. 2011;186(10):5696-5705. 21460208 10.4049/jimmunol.1001523
    • (2011) J Immunol , vol.186 , Issue.10 , pp. 5696-5705
    • Bonnefoy, F.1    Perruche, S.2    Couturier, M.3
  • 57
    • 4043092238 scopus 로고    scopus 로고
    • Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes
    • 15254595, 449750
    • Munn DH Sharma MD Hou D: Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes. J Clin Invest. 2004;114(2):280-290. 15254595 10.1172/JCI21583 449750
    • (2004) J Clin Invest , vol.114 , Issue.2 , pp. 280-290
    • Munn, D.H.1    Sharma, M.D.2    Hou, D.3
  • 58
    • 34848915783 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase
    • 17710230, 1940240
    • Sharma MD Baban B Chandler P: Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase. J Clin Invest. 2007;117(9):2570-2582. 17710230 10.1172/JCI31911 1940240
    • (2007) J Clin Invest , vol.117 , Issue.9 , pp. 2570-2582
    • Sharma, M.D.1    Baban, B.2    Chandler, P.3
  • 59
    • 27144552597 scopus 로고    scopus 로고
    • + dendritic cells to acquire potent indoleamine 2,3-dioxygenase-dependent T cell regulatory functions via IFN Type 1 signaling
    • 16237046
    • Mellor AL Baban B Chandler PR: Cutting edge: CpG oligonucleotides induce splenic CD19 + dendritic cells to acquire potent indoleamine 2,3-dioxygenase-dependent T cell regulatory functions via IFN Type 1 signaling. J Immunol. 2005;175(9):5601-5605. 16237046 10.4049/jimmunol.175.9.5601
    • (2005) J Immunol , vol.175 , Issue.9 , pp. 5601-5605
    • Mellor, A.L.1    Baban, B.2    Chandler, P.R.3
  • 60
    • 80052020183 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells
    • 21804557
    • Pallotta MT Orabona C Volpi C: Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells. Nat Immunol. 2011;12(9):870-878. 21804557 10.1038/ni.2077
    • (2011) Nat Immunol , vol.12 , Issue.9 , pp. 870-878
    • Pallotta, M.T.1    Orabona, C.2    Volpi, C.3
  • 61
    • 33745026450 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cell-specific receptor ILT7-Fc epsilonRI gamma inhibits Toll-like receptor-induced interferon production
    • 16735691, 2118323
    • Cao W Rosen DB Ito T: Plasmacytoid dendritic cell-specific receptor ILT7-Fc epsilonRI gamma inhibits Toll-like receptor-induced interferon production. J Exp Med. 2006;203(6):1399-1405. 16735691 10.1084/jem.20052454 2118323
    • (2006) J Exp Med , vol.203 , Issue.6 , pp. 1399-1405
    • Cao, W.1    Rosen, D.B.2    Ito, T.3
  • 62
    • 0035905321 scopus 로고    scopus 로고
    • BDCA-2, a novel plasmacytoid dendritic cell-specific type II C-type lectin, mediates antigen capture and is a potent inhibitor of interferon alpha/beta induction
    • 11748283, 2193584
    • Dzionek A Sohma Y Nagafune J: BDCA-2, a novel plasmacytoid dendritic cell-specific type II C-type lectin, mediates antigen capture and is a potent inhibitor of interferon alpha/beta induction. J Exp Med. 2001;194(12):1823-1834. 11748283 10.1084/jem.194.12.1823 2193584
    • (2001) J Exp Med , vol.194 , Issue.12 , pp. 1823-1834
    • Dzionek, A.1    Sohma, Y.2    Nagafune, J.3
  • 63
    • 84873738307 scopus 로고    scopus 로고
    • Functions of TGF-β-exposed plasmacytoid dendritic cells
    • 23428227
    • Saas P Perruche S: Functions of TGF-β-exposed plasmacytoid dendritic cells. Crit Rev Immunol. 2012;32(6):529-553. 23428227 10.1615/CritRevImmunol.2013005868
    • (2012) Crit Rev Immunol , vol.32 , Issue.6 , pp. 529-553
    • Saas, P.1    Perruche, S.2
  • 64
    • 0030949479 scopus 로고    scopus 로고
    • The enigmatic plasmacytoid T cells develop into dendritic cells with interleukin (IL)-3 and CD40-ligand
    • 9091583, 2196227
    • Grouard G Rissoan MC Filgueira L: The enigmatic plasmacytoid T cells develop into dendritic cells with interleukin (IL)-3 and CD40-ligand. J Exp Med. 1997;185(6):1101-1111. 9091583 10.1084/jem.185.6.1101 2196227
    • (1997) J Exp Med , vol.185 , Issue.6 , pp. 1101-1111
    • Grouard, G.1    Rissoan, M.C.2    Filgueira, L.3
  • 65
    • 77954666119 scopus 로고    scopus 로고
    • Systematic cytokine receptor profiling reveals GM-CSF as a novel TLR-independent activator of human plasmacytoid predendritic cells
    • 20382843
    • Ghirelli C Zollinger R Soumelis V: Systematic cytokine receptor profiling reveals GM-CSF as a novel TLR-independent activator of human plasmacytoid predendritic cells. Blood. 2010;115(24):5037-5040. 20382843 10.1182/blood-2010-01-266932
    • (2010) Blood , vol.115 , Issue.24 , pp. 5037-5040
    • Ghirelli, C.1    Zollinger, R.2    Soumelis, V.3
  • 66
    • 84904305651 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells: development, functions, and role in atherosclerotic inflammation
    • 25120492, 4110479
    • Chistiakov DA Orekhov AN Sobenin IA: Plasmacytoid dendritic cells: development, functions, and role in atherosclerotic inflammation. Front Physiol. 2014;5:279. 25120492 10.3389/fphys.2014.00279 4110479
    • (2014) Front Physiol , vol.5 , pp. 279
    • Chistiakov, D.A.1    Orekhov, A.N.2    Sobenin, I.A.3
  • 67
    • 85009376389 scopus 로고    scopus 로고
    • Effects of Interferons and Viruses on Metabolism
    • 28066439, 5174094
    • Fritsch SD Weichhart T: Effects of Interferons and Viruses on Metabolism. Front Immunol. 2016;7:630. 28066439 10.3389/fimmu.2016.00630 5174094
    • (2016) Front Immunol , vol.7 , pp. 630
    • Fritsch, S.D.1    Weichhart, T.2
  • 68
    • 33748447541 scopus 로고    scopus 로고
    • Type I interferon in systemic lupus erythematosus and other autoimmune diseases
    • 16979570
    • Banchereau J Pascual V: Type I interferon in systemic lupus erythematosus and other autoimmune diseases. Immunity. 2006;25(3):383-392. 16979570 10.1016/j.immuni.2006.08.010
    • (2006) Immunity , vol.25 , Issue.3 , pp. 383-392
    • Banchereau, J.1    Pascual, V.2
  • 69
    • 84872053925 scopus 로고    scopus 로고
    • Crosstalk between neutrophils, B-1a cells and plasmacytoid dendritic cells initiates autoimmune diabetes
    • 23242473
    • Diana J Simoni Y Furio L: Crosstalk between neutrophils, B-1a cells and plasmacytoid dendritic cells initiates autoimmune diabetes. Nat Med. 2013;19(1):65-73. 23242473 10.1038/nm.3042
    • (2013) Nat Med , vol.19 , Issue.1 , pp. 65-73
    • Diana, J.1    Simoni, Y.2    Furio, L.3
  • 70
    • 84893081873 scopus 로고    scopus 로고
    • Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis
    • 24350901, 4040466
    • van Bon L Affandi AJ Broen J: Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis. N Engl J Med. 2014;370(5):433-443. 24350901 10.1056/NEJMoa1114576 4040466
    • (2014) N Engl J Med , vol.370 , Issue.5 , pp. 433-443
    • van Bon, L.1    Affandi, A.J.2    Broen, J.3
  • 71
    • 22344438901 scopus 로고    scopus 로고
    • Plasmacytoid predendritic cells initiate psoriasis through interferon-alpha production
    • 15998792, 2212894
    • Nestle FO Conrad C Tun-Kyi A: Plasmacytoid predendritic cells initiate psoriasis through interferon-alpha production. J Exp Med. 2005;202(1):135-143. 15998792 10.1084/jem.20050500 2212894
    • (2005) J Exp Med , vol.202 , Issue.1 , pp. 135-143
    • Nestle, F.O.1    Conrad, C.2    Tun-Kyi, A.3
  • 72
    • 84946762057 scopus 로고    scopus 로고
    • Proteinase 3 on apoptotic cells disrupts immune silencing in autoimmune vasculitis
    • 26436651, 4639994
    • Millet A Martin KR Bonnefoy F: Proteinase 3 on apoptotic cells disrupts immune silencing in autoimmune vasculitis. J Clin Invest. 2015;125(11):4107-4121. 26436651 10.1172/JCI78182 4639994
    • (2015) J Clin Invest , vol.125 , Issue.11 , pp. 4107-4121
    • Millet, A.1    Martin, K.R.2    Bonnefoy, F.3
  • 73
    • 84863779459 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells and Th17 immune response contribution in gastrointestinal acute graft-versus-host disease
    • 22333879
    • Bossard C Malard F Arbez J: Plasmacytoid dendritic cells and Th17 immune response contribution in gastrointestinal acute graft-versus-host disease. Leukemia. 2012;26(7):1471-1474. 22333879 10.1038/leu.2012.41
    • (2012) Leukemia , vol.26 , Issue.7 , pp. 1471-1474
    • Bossard, C.1    Malard, F.2    Arbez, J.3
  • 74
    • 84888794996 scopus 로고    scopus 로고
    • Increased plasmacytoid dendritic cells and RORγt-expressing immune effectors in cutaneous acute graft-versus-host disease
    • 23990625
    • Malard F Bossard C Brissot E: Increased plasmacytoid dendritic cells and RORγt-expressing immune effectors in cutaneous acute graft-versus-host disease. J Leukoc Biol. 2013;94(6):1337-1343. 23990625 10.1189/jlb.0513295
    • (2013) J Leukoc Biol , vol.94 , Issue.6 , pp. 1337-1343
    • Malard, F.1    Bossard, C.2    Brissot, E.3
  • 75
    • 84866379222 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells in atherosclerosis
    • 22754539, 3385355
    • Döring Y Zernecke A: Plasmacytoid dendritic cells in atherosclerosis. Front Physiol. 2012;3:230. 22754539 10.3389/fphys.2012.00230 3385355
    • (2012) Front Physiol , vol.3 , pp. 230
    • Döring, Y.1    Zernecke, A.2
  • 76
    • 0035883082 scopus 로고    scopus 로고
    • Depletion of circulating natural type 1 interferon-producing cells in HIV-infected AIDS patients
    • 11493432
    • Soumelis V Scott I Gheyas F: Depletion of circulating natural type 1 interferon-producing cells in HIV-infected AIDS patients. Blood. 2001;98(4):906-912. 11493432 10.1182/blood.V98.4.906
    • (2001) Blood , vol.98 , Issue.4 , pp. 906-912
    • Soumelis, V.1    Scott, I.2    Gheyas, F.3
  • 77
    • 39349111657 scopus 로고    scopus 로고
    • The role of plasmacytoid dendritic cell-derived IFN alpha in antiviral immunity
    • 18298384
    • Szabo G Dolganiuc A: The role of plasmacytoid dendritic cell-derived IFN alpha in antiviral immunity. Crit Rev Immunol. 2008;28(1):61-94. 18298384 10.1615/CritRevImmunol.v28.i1.40
    • (2008) Crit Rev Immunol , vol.28 , Issue.1 , pp. 61-94
    • Szabo, G.1    Dolganiuc, A.2
  • 78
    • 52649164583 scopus 로고    scopus 로고
    • RAPping production of type I interferon in pDCs through mTOR
    • 18800159
    • Costa-Mattioli M Sonenberg N: RAPping production of type I interferon in pDCs through mTOR. Nat Immunol. 2008;9(10):1097-1099. 18800159 10.1038/ni1008-1097
    • (2008) Nat Immunol , vol.9 , Issue.10 , pp. 1097-1099
    • Costa-Mattioli, M.1    Sonenberg, N.2
  • 79
    • 52549127241 scopus 로고    scopus 로고
    • Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway
    • 18758466, 3732485
    • Cao W Manicassamy S Tang H: Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway. Nat Immunol. 2008;9(10):1157-1164. 18758466 10.1038/ni.1645 3732485
    • (2008) Nat Immunol , vol.9 , Issue.10 , pp. 1157-1164
    • Cao, W.1    Manicassamy, S.2    Tang, H.3
  • 80
    • 84991619006 scopus 로고    scopus 로고
    • HIF1α and metabolic reprogramming in inflammation
    • 27571407, 5096812
    • Corcoran SE O'Neill LA: HIF1α and metabolic reprogramming in inflammation. J Clin Invest. 2016;126(10):3699-3707. 27571407 10.1172/JCI84431 5096812
    • (2016) J Clin Invest , vol.126 , Issue.10 , pp. 3699-3707
    • Corcoran, S.E.1    O'Neill, L.A.2
  • 81
    • 1842855242 scopus 로고    scopus 로고
    • Characterization of plasmacytoid dendritic cells in inflammatory arthritis synovial fluid
    • 14762226
    • Van Krinks CH Matyszak MK Gaston JS: Characterization of plasmacytoid dendritic cells in inflammatory arthritis synovial fluid. Rheumatology (Oxford). 2004;43(4):453-460. 14762226 10.1093/rheumatology/keh115
    • (2004) Rheumatology (Oxford) , vol.43 , Issue.4 , pp. 453-460
    • Van Krinks, C.H.1    Matyszak, M.K.2    Gaston, J.S.3
  • 82
    • 4043170537 scopus 로고    scopus 로고
    • Characterization and recruitment of plasmacytoid dendritic cells in synovial fluid and tissue of patients with chronic inflammatory arthritis
    • 15295000
    • Lande R Giacomini E Serafini B: Characterization and recruitment of plasmacytoid dendritic cells in synovial fluid and tissue of patients with chronic inflammatory arthritis. J Immunol. 2004;173(4):2815-2824. 15295000 10.4049/jimmunol.173.4.2815
    • (2004) J Immunol , vol.173 , Issue.4 , pp. 2815-2824
    • Lande, R.1    Giacomini, E.2    Serafini, B.3
  • 83
    • 29144531808 scopus 로고    scopus 로고
    • Rheumatoid arthritis synovium contains plasmacytoid dendritic cells
    • 15743469, 1065313
    • Cavanagh LL Boyce A Smith L: Rheumatoid arthritis synovium contains plasmacytoid dendritic cells. Arthritis Res Ther. 2005;7(2):R230-240. 15743469 10.1186/ar1467 1065313
    • (2005) Arthritis Res Ther , vol.7 , Issue.2 , pp. R230-240
    • Cavanagh, L.L.1    Boyce, A.2    Smith, L.3
  • 84
    • 85019547250 scopus 로고    scopus 로고
    • Crucial role of plasmacytoid dendritic cells in the development of acute colitis through the regulation of intestinal inflammation
    • 27848952, In press.
    • Arimura K Takagi H Uto T: Crucial role of plasmacytoid dendritic cells in the development of acute colitis through the regulation of intestinal inflammation. Mucosal Immunol. 2017; In press. 27848952 10.1038/mi.2016.96
    • (2017) Mucosal Immunol
    • Arimura, K.1    Takagi, H.2    Uto, T.3
  • 85
    • 1842631428 scopus 로고    scopus 로고
    • Recognition of single-stranded RNA viruses by Toll-like receptor 7
    • 15034168, 397437
    • Lund JM Alexopoulou L Sato A: Recognition of single-stranded RNA viruses by Toll-like receptor 7. Proc Natl Acad Sci U S A. 2004;101(15):5598-5603. 15034168 10.1073/pnas.0400937101 397437
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.15 , pp. 5598-5603
    • Lund, J.M.1    Alexopoulou, L.2    Sato, A.3
  • 86
    • 84901937811 scopus 로고    scopus 로고
    • Liver X receptors in lipid metabolism: opportunities for drug discovery
    • 24833295
    • Hong C Tontonoz P: Liver X receptors in lipid metabolism: opportunities for drug discovery. Nat Rev Drug Discov. 2014;13(6):433-444. 24833295 10.1038/nrd4280
    • (2014) Nat Rev Drug Discov , vol.13 , Issue.6 , pp. 433-444
    • Hong, C.1    Tontonoz, P.2
  • 87
    • 38849122775 scopus 로고    scopus 로고
    • Liver X receptors (LXRs). Part I: structure, function, regulation of activity, and role in lipid metabolism
    • 18063918
    • Wójcicka G Jamroz-Wisniewska A Horoszewicz K: Liver X receptors (LXRs). Part I: structure, function, regulation of activity, and role in lipid metabolism. Postepy Hig Med Dosw (Online). 2007;61:736-759. 18063918
    • (2007) Postepy Hig Med Dosw (Online) , vol.61 , pp. 736-759
    • Wójcicka, G.1    Jamroz-Wisniewska, A.2    Horoszewicz, K.3
  • 88
    • 84865305956 scopus 로고    scopus 로고
    • Liver X receptor and peroxisome proliferator-activated receptor as integrators of lipid homeostasis and immunity
    • 22889216, 4007066
    • Kidani Y Bensinger SJ: Liver X receptor and peroxisome proliferator-activated receptor as integrators of lipid homeostasis and immunity. Immunol Rev. 2012;249(1):72-83. 22889216 10.1111/j.1600-065X.2012.01153.x 4007066
    • (2012) Immunol Rev , vol.249 , Issue.1 , pp. 72-83
    • Kidani, Y.1    Bensinger, S.J.2
  • 89
    • 78349283454 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha target genes
    • 20936127, 2948931, pii: 612089.
    • Rakhshandehroo M Knoch B Muller M: Peroxisome proliferator-activated receptor alpha target genes. PPAR Res. 2010;2010; pii: 612089. 20936127 10.1155/2010/612089 2948931
    • (2010) PPAR Res , vol.2010
    • Rakhshandehroo, M.1    Knoch, B.2    Muller, M.3
  • 90
    • 84881135383 scopus 로고    scopus 로고
    • The role of lipid-activated nuclear receptors in shaping macrophage and dendritic cell function: From physiology to pathology
    • 23905916
    • Kiss M Czimmerer Z Nagy L: The role of lipid-activated nuclear receptors in shaping macrophage and dendritic cell function: From physiology to pathology. J Allergy Clin Immunol. 2013;132(2):264-286. 23905916 10.1016/j.jaci.2013.05.044
    • (2013) J Allergy Clin Immunol , vol.132 , Issue.2 , pp. 264-286
    • Kiss, M.1    Czimmerer, Z.2    Nagy, L.3
  • 91
    • 0036251153 scopus 로고    scopus 로고
    • SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver
    • 11994399, 150968
    • Horton JD Goldstein JL Brown MS: SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest. 2002;109(9):1125-1131. 11994399 10.1172/JCI15593 150968
    • (2002) J Clin Invest , vol.109 , Issue.9 , pp. 1125-1131
    • Horton, J.D.1    Goldstein, J.L.2    Brown, M.S.3
  • 92
    • 38549141572 scopus 로고    scopus 로고
    • Cellular cholesterol trafficking and compartmentalization
    • 18216769
    • Ikonen E: Cellular cholesterol trafficking and compartmentalization. Nat Rev Mol Cell Biol. 2008;9(2):125-138. 18216769 10.1038/nrm2336
    • (2008) Nat Rev Mol Cell Biol , vol.9 , Issue.2 , pp. 125-138
    • Ikonen, E.1
  • 93
    • 33750927892 scopus 로고    scopus 로고
    • ATP-Binding cassette cholesterol transporters and cardiovascular disease
    • 17095732
    • Oram JF Vaughan AM: ATP-Binding cassette cholesterol transporters and cardiovascular disease. Circ Res. 2006;99(10):1031-1043. 17095732 10.1161/01.RES.0000250171.54048.5c
    • (2006) Circ Res , vol.99 , Issue.10 , pp. 1031-1043
    • Oram, J.F.1    Vaughan, A.M.2
  • 94
    • 79954596966 scopus 로고    scopus 로고
    • Liver x receptors in atherosclerosis and inflammation
    • 21493922, 3082200
    • Im SS Osborne TF: Liver x receptors in atherosclerosis and inflammation. Circ Res. 2011;108(8):996-1001. 21493922 10.1161/CIRCRESAHA.110.226878 3082200
    • (2011) Circ Res , vol.108 , Issue.8 , pp. 996-1001
    • Im, S.S.1    Osborne, T.F.2
  • 95
    • 13644259004 scopus 로고    scopus 로고
    • ApoE-mediated cholesterol efflux from macrophages: separation of autocrine and paracrine effects
    • 15509658
    • Dove DE Linton MF Fazio S: ApoE-mediated cholesterol efflux from macrophages: separation of autocrine and paracrine effects. Am J Physiol Cell Physiol. 2005;288(3):C586-592. 15509658 10.1152/ajpcell.00210.2004
    • (2005) Am J Physiol Cell Physiol , vol.288 , Issue.3 , pp. C586-592
    • Dove, D.E.1    Linton, M.F.2    Fazio, S.3
  • 96
    • 77953767546 scopus 로고    scopus 로고
    • The E3 ubiquitin ligase IDOL induces the degradation of the low density lipoprotein receptor family members VLDLR and ApoER2
    • 20427281, 2888382
    • Hong C Duit S Jalonen P: The E3 ubiquitin ligase IDOL induces the degradation of the low density lipoprotein receptor family members VLDLR and ApoER2. J Biol Chem. 2010;285(26):19720-19726. 20427281 10.1074/jbc.M110.123729 2888382
    • (2010) J Biol Chem , vol.285 , Issue.26 , pp. 19720-19726
    • Hong, C.1    Duit, S.2    Jalonen, P.3
  • 97
    • 77954240134 scopus 로고    scopus 로고
    • Statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, function as inhibitors of cellular and molecular components involved in type I interferon production
    • 20506142
    • Amuro H Ito T Miyamoto R: Statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, function as inhibitors of cellular and molecular components involved in type I interferon production. Arthritis Rheum. 2010;62(7):2073-2085. 20506142 10.1002/art.27478
    • (2010) Arthritis Rheum , vol.62 , Issue.7 , pp. 2073-2085
    • Amuro, H.1    Ito, T.2    Miyamoto, R.3
  • 98
    • 79957899628 scopus 로고    scopus 로고
    • Mechanisms for the anti-inflammatory effects of statins
    • 21412153
    • Bu DX Griffin G Lichtman AH: Mechanisms for the anti-inflammatory effects of statins. Curr Opin Lipidol. 2011;22(3):165-170. 21412153 10.1097/MOL.0b013e3283453e41
    • (2011) Curr Opin Lipidol , vol.22 , Issue.3 , pp. 165-170
    • Bu, D.X.1    Griffin, G.2    Lichtman, A.H.3
  • 99
    • 85015669653 scopus 로고    scopus 로고
    • LXR agonist treatment of blastic plasmacytoid dendritic cell neoplasm restores cholesterol efflux and triggers apoptosis
    • 27702801, 5271175
    • Ceroi A Masson D Roggy A: LXR agonist treatment of blastic plasmacytoid dendritic cell neoplasm restores cholesterol efflux and triggers apoptosis. Blood. 2016;128(23):2694-2707. 27702801 10.1182/blood-2016-06-724807 5271175
    • (2016) Blood , vol.128 , Issue.23 , pp. 2694-2707
    • Ceroi, A.1    Masson, D.2    Roggy, A.3
  • 100
    • 68949145931 scopus 로고    scopus 로고
    • Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR
    • 19646905, 2791787
    • A-Gonzalez N Bensinger SJ Hong C: Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR. Immunity. 2009;31(2):245-258. 19646905 10.1016/j.immuni.2009.06.018 2791787
    • (2009) Immunity , vol.31 , Issue.2 , pp. 245-258
    • A-Gonzalez, N.1    Bensinger, S.J.2    Hong, C.3
  • 101
    • 84950247027 scopus 로고    scopus 로고
    • Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling
    • 26686653, 4783382
    • York AG Williams KJ Argus JP: Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling. Cell. 2015;163(7):1716-1729. 26686653 10.1016/j.cell.2015.11.045 4783382
    • (2015) Cell , vol.163 , Issue.7 , pp. 1716-1729
    • York, A.G.1    Williams, K.J.2    Argus, J.P.3
  • 102
    • 85012863046 scopus 로고    scopus 로고
    • Mining the Human Gut Microbiota for Immunomodulatory Organisms
    • 28215708
    • Geva-Zatorsky N Sefik E Kua L: Mining the Human Gut Microbiota for Immunomodulatory Organisms. Cell. 2017;168(5):928-943.e911. 28215708 10.1016/j.cell.2017.01.022
    • (2017) Cell , vol.168 , Issue.5 , pp. 928-943.e911
    • Geva-Zatorsky, N.1    Sefik, E.2    Kua, L.3
  • 103
    • 84902078711 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor valproic acid affects plasmacytoid dendritic cells phenotype and function
    • 24742998
    • Arbez J Lamarthee B Gaugler B: Histone deacetylase inhibitor valproic acid affects plasmacytoid dendritic cells phenotype and function. Immunobiology. 2014;219(8):637-643. 24742998 10.1016/j.imbio.2014.03.013
    • (2014) Immunobiology , vol.219 , Issue.8 , pp. 637-643
    • Arbez, J.1    Lamarthee, B.2    Gaugler, B.3
  • 104
    • 84968616731 scopus 로고    scopus 로고
    • Molecular Pathways: Immunosuppressive Roles of IRE1α-XBP1 Signaling in Dendritic Cells of the Tumor Microenvironment
    • 26979393, 4854763
    • Cubillos-Ruiz JR Bettigole SE Glimcher LH: Molecular Pathways: Immunosuppressive Roles of IRE1α-XBP1 Signaling in Dendritic Cells of the Tumor Microenvironment. Clin Cancer Res. 2016;22(9):2121-2126. 26979393 10.1158/1078-0432.CCR-15-1570 4854763
    • (2016) Clin Cancer Res , vol.22 , Issue.9 , pp. 2121-2126
    • Cubillos-Ruiz, J.R.1    Bettigole, S.E.2    Glimcher, L.H.3
  • 105
    • 78751522626 scopus 로고    scopus 로고
    • Bortezomib suppresses function and survival of plasmacytoid dendritic cells by targeting intracellular trafficking of Toll-like receptors and endoplasmic reticulum homeostasis
    • 20956804
    • Hirai M Kadowaki N Kitawaki T: Bortezomib suppresses function and survival of plasmacytoid dendritic cells by targeting intracellular trafficking of Toll-like receptors and endoplasmic reticulum homeostasis. Blood. 2011;117(2):500-509. 20956804 10.1182/blood-2010-05-284737
    • (2011) Blood , vol.117 , Issue.2 , pp. 500-509
    • Hirai, M.1    Kadowaki, N.2    Kitawaki, T.3


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