The anti-inflammatory effects of platelet-derived microparticles in human plasmacytoid dendritic cells involve liver X receptor activation

Haematologica

Volumn 101, Issue 3, 2016, Pages e72-e76

  Ceroi, Adam ^a,b,c,d   Delettre, Fanny Angelot ^a,b,c,d   Marotel, Charline ^a,b,c   Gauthier, Thierry ^a,b,c,d   Asgarova, Afag ^a,b,c   Biichlé, Sabéha ^a,b,c,d   Duperrier, Anne ^a,b,c   Mourey, Guillaume ^a,b,c   Perruche, Sylvain ^a,b,c,d   Lagrost, Laurent ^c,d,e,f   Masson, David ^c,d,e,f   Saas, Philippe ^a,b,c,d,g  

^a INSERM   (France)

^b ETABLISSEMENT FRANÇAIS DU SANG   (France)

^c UNIVERSITÉ BOURGOGNE FRANCHE COMTÉ   (France)

^d LipSTIC LabEx   (France)

^e Institut Médical de Génétique et d Immunologie   (France)

^f DIJON UNIVERSITY HOSPITAL   (France)

^g UNIVERSITY HOSPITAL OF BESANÇON   (France)

Author keywords

Ectosomes; Extracellular vesicles; Inflammation; LXR; Microvesicles; Plasmacytoid dendritic cells

Indexed keywords

22 HYDROXYCHOLESTEROL; 3 [3 [[2 CHLORO 3 (TRIFLUOROMETHYL)BENZYL](2 DIPHENYLETHYL)AMINO]PROPOXY]PHENYLACETIC ACID; ABC TRANSPORTER A1; ALPHA INTERFERON; ANGIOGENESIS INHIBITOR; CD123 ANTIGEN; CD303 ANTIGEN; CPG OLIGODEOXYNUCLEOTIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; LIVER X RECEPTOR; MESSENGER RNA; MONOCLONAL ANTIBODY; N (2,2,2 TRIFLUOROETHYL) N [4 (2,2,2 TRIFLUORO 1 HYDROXY 1 TRIFLUOROMETHYLETHYL)PHENYL]BENZENESULFONAMIDE; PHOSPHATIDYLSERINE; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 22-HYDROXYCHOLESTEROL; 4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE; ABCA1 PROTEIN, HUMAN; ANGIOGENIC PROTEIN; BAI1 PROTEIN, HUMAN; BENZOIC ACID DERIVATIVE; BENZYLAMINE DERIVATIVE; CHOLESTEROL DERIVATIVE; CPG-OLIGONUCLEOTIDE; FLUORINATED HYDROCARBON; IMIDAZOLE DERIVATIVE; NR1H3 PROTEIN, HUMAN; OLIGODEOXYRIBONUCLEOTIDE; PHENYLENEDIAMINE DERIVATIVE; RESIQUIMOD; SREBF1 PROTEIN, HUMAN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; SULFONAMIDE; TLR7 PROTEIN, HUMAN; TO-901317; TOLL LIKE RECEPTOR 7; TUMOR NECROSIS FACTOR;

ANTIINFLAMMATORY ACTIVITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOMETRY; DOWN REGULATION; GENE EXPRESSION; HUMAN; HUMAN CELL; LETTER; NORMAL HUMAN; PARTICLE SIZE; PLASMACYTOID DENDRITIC CELL; PLATELET MICROPARTICLE; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; AGONISTS; ANTAGONISTS AND INHIBITORS; CHEMISTRY; CYTOLOGY; DENDRITIC CELL; DRUG EFFECTS; ENDOTHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; INNATE IMMUNITY; MEMBRANE MICROPARTICLE; PRIMARY CELL CULTURE; THROMBOCYTE;

ANGIOGENIC PROTEINS; ATP BINDING CASSETTE TRANSPORTER 1; BENZOATES; BENZYLAMINES; BLOOD PLATELETS; CELL-DERIVED MICROPARTICLES; DENDRITIC CELLS; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION; HUMANS; HYDROCARBONS, FLUORINATED; HYDROXYCHOLESTEROLS; IMIDAZOLES; IMMUNITY, INNATE; LIVER X RECEPTORS; NF-KAPPA B; OLIGODEOXYRIBONUCLEOTIDES; PHENYLENEDIAMINES; PRIMARY CELL CULTURE; SIGNAL TRANSDUCTION; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; SULFONAMIDES; TOLL-LIKE RECEPTOR 7; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84959290932     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2015.135459     Document Type: Letter

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