Proteinase 3 on apoptotic cells disrupts immune silencing in autoimmune vasculitis

Journal of Clinical Investigation

Volumn 125, Issue 11, 2015, Pages 4107-4121

  Millet, Arnaud ^a,b,c   Martin, Katherine R ^a,b,c   Bonnefoy, Francis ^d   Saas, Philippe ^d   Mocek, Julie ^a,b,c   Alkan, Manal ^a,b,c   Terrier, Benjamin ^a,b,c,e   Kerstein, Anja ^f   Tamassia, Nicola ^g   Satyanarayanan, Senthil Kumaran ^h   Ariel, Amiram ^h   Ribeil, Jean Antoine ^b,i   Guillevin, Loïc ^e   Cassatella, Marco A ^g   Mueller, Antje ^f   Thieblemont, Nathalie ^a,b,c   Lamprecht, Peter ^f   Mouthon, Luc ^a,b,c,e   Perruche, Sylvain ^d   Witko Sarsat, Véronique ^a,b,c  

^a INSTITUT COCHIN   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c Labex Inflamex   (France)

^d UNIVERSITÉ BOURGOGNE FRANCHE COMTÉ   (France)

^e University Bourgogne Franche Comté ^*  (France)

^f UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^g UNIVERSITY OF VERONA   (Italy)

^h UNIVERSITY OF HAIFA   (Israel)

ⁱ HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CHEMOKINE; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 1 RECEPTOR TYPE I; MYELOBLASTIN; MYELOID DIFFERENTIATION FACTOR 88; NEUTROPHIL CYTOPLASMIC ANTIBODY; AUTOANTIGEN; CYTOKINE; IL1R1 PROTEIN, MOUSE; MYD88 PROTEIN, MOUSE; NITRIC OXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTOIMMUNE DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; GENE DISRUPTION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; MACROPHAGE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TH2 CELL; TH9 CELL; VASCULITIS; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL MEMBRANE; DEFICIENCY; DENDRITIC CELL; ENZYMOLOGY; IMMUNOLOGY; LUNG; PATHOLOGY; PERITONITIS; PHAGOCYTOSIS; PHYSIOLOGY; SECRETION (PROCESS); T LYMPHOCYTE SUBPOPULATION; TUMOR MICROENVIRONMENT; WEGENER GRANULOMATOSIS;

ANIMALS; ANTIBODIES, ANTINEUTROPHIL CYTOPLASMIC; APOPTOSIS; AUTOANTIGENS; CELL MEMBRANE; CELLULAR MICROENVIRONMENT; CYTOKINES; DENDRITIC CELLS; GRANULOCYTE COLONY-STIMULATING FACTOR; GRANULOMATOSIS WITH POLYANGIITIS; HUMANS; LUNG; MACROPHAGES; MICE; MICE, INBRED C57BL; MYELOBLASTIN; MYELOID DIFFERENTIATION FACTOR 88; NEUTROPHILS; NITRIC OXIDE; PERITONITIS; PHAGOCYTOSIS; RECEPTORS, INTERLEUKIN-1 TYPE I; SIGNAL TRANSDUCTION; T-LYMPHOCYTE SUBSETS;

EID: 84946762057     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI78182     Document Type: Article

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