메뉴 건너뛰기




Volumn 12, Issue 12, 2016, Pages 716-730

New insights into the immunopathogenesis of systemic lupus erythematosus

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; INTERFERON; MICRORNA; NUCLEIC ACID; ANTIGEN ANTIBODY COMPLEX; TOLL LIKE RECEPTOR;

EID: 84996604183     PISSN: 17594790     EISSN: 17594804     Source Type: Journal    
DOI: 10.1038/nrrheum.2016.186     Document Type: Review
Times cited : (920)

References (236)
  • 1
    • 33746936116 scopus 로고    scopus 로고
    • Mortality in systemic lupus erythematosus
    • Bernatsky S., et al. Mortality in systemic lupus erythematosus. Arthritis Rheum. 54, 2550-2557 (2006
    • (2006) Arthritis Rheum , vol.54 , pp. 2550-2557
    • Bernatsky, S.1
  • 2
    • 79958818391 scopus 로고    scopus 로고
    • Cost of illness studies in systemic lupus erythematosus: A systematic review
    • Zhu T. Y., Tam L. S., & Li E. K. Cost of illness studies in systemic lupus erythematosus: a systematic review. Arthritis Care Res. (Hoboken) 63, 751-760 (2011
    • (2011) Arthritis Care Res. (Hoboken , vol.63 , pp. 751-760
    • Zhu, T.Y.1    Tam, L.S.2    Li, E.K.3
  • 3
    • 0028288510 scopus 로고
    • Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes
    • Casciola-Rosen L. A., Anhalt G., & Rosen A. Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes. J. Exp. Med. 179, 1317-1330 (1994
    • (1994) J. Exp. Med , vol.179 , pp. 1317-1330
    • Casciola-Rosen, L.A.1    Anhalt, G.2    Rosen, A.3
  • 5
    • 84956739280 scopus 로고    scopus 로고
    • Circulating apoptotic microparticles in systemic lupus erythematosus patients drive the activation of dendritic cell subsets and prime neutrophils for netosis
    • Dieker J., et al. Circulating apoptotic microparticles in systemic lupus erythematosus patients drive the activation of dendritic cell subsets and prime neutrophils for NETosis. Arthritis Rheumatol. 68, 462-472 (2016
    • (2016) Arthritis Rheumatol , vol.68 , pp. 462-472
    • Dieker, J.1
  • 6
    • 0037061453 scopus 로고    scopus 로고
    • Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
    • Leadbetter E. A., et al. Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors. Nature 416, 603-607 (2002
    • (2002) Nature , vol.416 , pp. 603-607
    • Leadbetter, E.A.1
  • 7
    • 84938690926 scopus 로고    scopus 로고
    • Pathophysiology of cutaneous lupus erythematosus
    • Achtman J. C., & Werth V. P. Pathophysiology of cutaneous lupus erythematosus. Arthritis Res. Ther. 17, 182 (2015
    • (2015) Arthritis Res. Ther , vol.17 , pp. 182
    • Achtman, J.C.1    Werth, V.P.2
  • 8
    • 33746864127 scopus 로고    scopus 로고
    • Sex and systemic lupus erythematosus: The role of the sex hormones estrogen and prolactin on the regulation of autoreactive B cells
    • Grimaldi C. M. Sex and systemic lupus erythematosus: the role of the sex hormones estrogen and prolactin on the regulation of autoreactive B cells. Curr. Opin. Rheumatol. 18, 456-461 (2006
    • (2006) Curr. Opin. Rheumatol , vol.18 , pp. 456-461
    • Grimaldi, C.M.1
  • 10
  • 11
    • 84950146989 scopus 로고    scopus 로고
    • Ultraviolet light converts propranolol a nonselective β blocker and potential lupus-inducing drug into a proinflammatory ahr ligand
    • Dorgham K., et al. Ultraviolet light converts propranolol a nonselective β blocker and potential lupus-inducing drug into a proinflammatory AhR ligand. Eur. J. Immunol. 45, 3174-3187 (2015
    • (2015) Eur. J. Immunol , vol.45 , pp. 3174-3187
    • Dorgham, K.1
  • 12
    • 84899506816 scopus 로고    scopus 로고
    • Viruses as potential pathogenic agents in systemic lupus erythematosus
    • Nelson P., Rylance P., Roden D., Trela M., & Tugnet N. Viruses as potential pathogenic agents in systemic lupus erythematosus. Lupus 23, 596-605 (2014
    • (2014) Lupus , vol.23 , pp. 596-605
    • Nelson, P.1    Rylance, P.2    Roden, D.3    Trela, M.4    Tugnet, N.5
  • 13
    • 3442889943 scopus 로고    scopus 로고
    • Association between systemic lupus erythematosus and Helicobacter pylori seronegativity
    • Sawalha A. H., Schmid W. R., Binder S. R., Bacino D. K., & Harley J. B. Association between systemic lupus erythematosus and Helicobacter pylori seronegativity. J. Rheumatol. 31, 1546-1550 (2004
    • (2004) J. Rheumatol , vol.31 , pp. 1546-1550
    • Sawalha, A.H.1    Schmid, W.R.2    Binder, S.R.3    Bacino, D.K.4    Harley, J.B.5
  • 14
    • 50949126626 scopus 로고    scopus 로고
    • The putative protective role of hepatitis B virus (HBV) infection from autoimmune disorders
    • Ram M., et al. The putative protective role of hepatitis B virus (HBV) infection from autoimmune disorders. Autoimmun. Rev. 7, 621-625 (2008
    • (2008) Autoimmun. Rev , vol.7 , pp. 621-625
    • Ram, M.1
  • 15
    • 3242808067 scopus 로고    scopus 로고
    • Toxoplasma gondii infection inhibits the development of lupus-like syndrome in autoimmune (New Zealand Black × New Zealand White) F1 mice
    • Chen M., et al. Toxoplasma gondii infection inhibits the development of lupus-like syndrome in autoimmune (New Zealand Black × New Zealand White) F1 mice. Int. Immunol. 16, 937-946 (2004
    • (2004) Int. Immunol , vol.16 , pp. 937-946
    • Chen, M.1
  • 16
    • 84953239488 scopus 로고    scopus 로고
    • Gene expression profiles from disease discordant twins suggest shared antiviral pathways and viral exposures among multiple systemic autoimmune diseases
    • Gan L., et al. Gene expression profiles from disease discordant twins suggest shared antiviral pathways and viral exposures among multiple systemic autoimmune diseases. PLoS ONE 10, e0142486 2015
    • (2015) Plos One , vol.10 , pp. e0142486
    • Gan, L.1
  • 17
    • 84900415568 scopus 로고    scopus 로고
    • The SLE transcriptome exhibits evidence of chronic endotoxin exposure and has widespread dysregulation of non-coding and coding RNAs
    • Shi L., et al. The SLE transcriptome exhibits evidence of chronic endotoxin exposure and has widespread dysregulation of non-coding and coding RNAs. PLoS ONE 9, e93846 2014
    • (2014) Plos One , vol.9 , pp. e93846
    • Shi, L.1
  • 18
    • 0028275841 scopus 로고
    • Elevated levels of soluble CD14 in serum of patients with systemic lupus erythematosus
    • Nockher W. A., Wigand R., Schoeppe W., & Scherberich J. E. Elevated levels of soluble CD14 in serum of patients with systemic lupus erythematosus. Clin. Exp. Immunol. 96, 15-19 (1994
    • (1994) Clin. Exp. Immunol , vol.96 , pp. 15-19
    • Nockher, W.A.1    Wigand, R.2    Schoeppe, W.3    Scherberich, J.E.4
  • 19
    • 84864281576 scopus 로고    scopus 로고
    • PDTC attenuate LPS-induced kidney injury in systemic lupus erythematosus-prone MRL/lpr mice
    • Zhai J. X., et al. PDTC attenuate LPS-induced kidney injury in systemic lupus erythematosus-prone MRL/lpr mice. Mol. Biol. Rep. 39, 6763-6771 (2012
    • (2012) Mol. Biol. Rep , vol.39 , pp. 6763-6771
    • Zhai, J.X.1
  • 20
    • 16644366474 scopus 로고    scopus 로고
    • Toll-like receptors: Linking innate and adaptive immunity
    • Pasare C., & Medzhitov R. Toll-like receptors: linking innate and adaptive immunity. Microbes Infect. 6, 1382-1387 (2004
    • (2004) Microbes Infect , vol.6 , pp. 1382-1387
    • Pasare, C.1    Medzhitov, R.2
  • 21
    • 84937611284 scopus 로고    scopus 로고
    • Amyloid-DNA composites of bacterial biofilms stimulate autoimmunity
    • Gallo P. M., et al. Amyloid-DNA composites of bacterial biofilms stimulate autoimmunity. Immunity 42, 1171-1184 (2015
    • (2015) Immunity , vol.42 , pp. 1171-1184
    • Gallo, P.M.1
  • 22
    • 84897138296 scopus 로고    scopus 로고
    • Role of the microbiota in immunity and inflammation
    • Belkaid Y., & Hand T. W. Role of the microbiota in immunity and inflammation. Cell 157, 121-141 (2014
    • (2014) Cell , vol.157 , pp. 121-141
    • Belkaid, Y.1    Hand, T.W.2
  • 23
    • 84908425997 scopus 로고    scopus 로고
    • Intestinal dysbiosis associated with systemic lupus erythematosus
    • Hevia A., et al. Intestinal dysbiosis associated with systemic lupus erythematosus. mBio 5, e01548-e01514 2014
    • (2014) MBio , vol.5 , pp. e01548-e011514
    • Hevia, A.1
  • 24
    • 84944382714 scopus 로고    scopus 로고
    • Impact of dietary deviation on disease progression and gut microbiome composition in lupus-prone SNF1 mice
    • Johnson B. M., Gaudreau M. C., Al Gadban M. M., Gudi R., & Vasu C. Impact of dietary deviation on disease progression and gut microbiome composition in lupus-prone SNF1 mice. Clin. Exp. Immunol. 181, 323-337 (2015
    • (2015) Clin. Exp. Immunol , vol.181 , pp. 323-337
    • Johnson, B.M.1    Gaudreau, M.C.2    Al Gadban, M.M.3    Gudi, R.4    Vasu, C.5
  • 26
    • 84890564250 scopus 로고    scopus 로고
    • Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
    • Furusawa Y., et al. Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells. Nature 504, 446-450 (2013
    • (2013) Nature , vol.504 , pp. 446-450
    • Furusawa, Y.1
  • 27
    • 84890550163 scopus 로고    scopus 로고
    • Metabolites produced by commensal bacteria promote peripheral regulatory T cell generation
    • Arpaia N., et al. Metabolites produced by commensal bacteria promote peripheral regulatory T cell generation. Nature 504, 451-455 (2013
    • (2013) Nature , vol.504 , pp. 451-455
    • Arpaia, N.1
  • 28
    • 84923116269 scopus 로고    scopus 로고
    • Commensal microbiotqa nfluence systemic autoimmune responses
    • Van Praet J. T., et al. Commensal microbiota influence systemic autoimmune responses. EMBO J. 34, 466-474 (2015
    • (2015) EMBO J. , vol.34 , pp. 466-474
    • An Praet, J.T.1
  • 29
    • 17244373451 scopus 로고    scopus 로고
    • Familial aggregation of systemic lupus erythematosus rheumatoid arthritis and other autoimmune diseases in 1,177 lupus patients from the gladel cohort
    • Alarcon-Segovia D., et al. Familial aggregation of systemic lupus erythematosus rheumatoid arthritis and other autoimmune diseases in 1,177 lupus patients from the GLADEL cohort. Arthritis Rheum. 52, 1138-1147 (2005
    • (2005) Arthritis Rheum , vol.52 , pp. 1138-1147
    • Alarcon-Segovia, D.1
  • 30
    • 84868444383 scopus 로고    scopus 로고
    • Unraveling multiple MHC gene associations with systemic lupus erythematosus: Model choice indicates a role for HLA alleles and non-HLA genes in Europeans
    • Morris D. L., et al. Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans. Am. J. Hum. Genet. 91, 778-793 (2012
    • (2012) Am. J. Hum. Genet , vol.91 , pp. 778-793
    • Morris, D.L.1
  • 31
    • 84875937513 scopus 로고    scopus 로고
    • Genetic susceptibility to SLE: Recent progress from GWAS
    • Cui Y., Sheng Y., & Zhang X. Genetic susceptibility to SLE: recent progress from GWAS. J. Autoimmun. 41, 25-33 (2013
    • (2013) J. Autoimmun , vol.41 , pp. 25-33
    • Cui, Y.1    Sheng, Y.2    Zhang, X.3
  • 32
    • 84923326765 scopus 로고    scopus 로고
    • Genetic and epigenetic fine mapping of causal autoimmune disease variants
    • Farh K. K., et al. Genetic and epigenetic fine mapping of causal autoimmune disease variants. Nature 518, 337-343 (2015
    • (2015) Nature , vol.518 , pp. 337-343
    • Farh, K.K.1
  • 33
    • 84948686586 scopus 로고    scopus 로고
    • Capture Hi C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci
    • Martin P., et al. Capture Hi C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci. Nat. Commun. 6, 10069 (2015
    • (2015) Nat. Commun , vol.6 , pp. 10069
    • Martin, P.1
  • 34
    • 84941025159 scopus 로고    scopus 로고
    • Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases
    • Li Y. R., et al. Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. Nat. Med. 21, 1018-1027 (2015
    • (2015) Nat. Med , vol.21 , pp. 1018-1027
    • Li, Y.R.1
  • 35
    • 67349120686 scopus 로고    scopus 로고
    • Genetic susceptibility to SLE: New insights from fine mapping and genome-wide association studies
    • Harley I. T., Kaufman K. M., Langefeld C. D., Harley J. B., & Kelly J. A. Genetic susceptibility to SLE: new insights from fine mapping and genome-wide association studies. Nat. Rev. Genet. 10, 285-290 (2009
    • (2009) Nat. Rev. Genet , vol.10 , pp. 285-290
    • Harley, I.T.1    Kaufman, K.M.2    Langefeld, C.D.3    Harley, J.B.4    Kelly, J.A.5
  • 36
    • 84864820680 scopus 로고    scopus 로고
    • Monogenic forms of systemic lupus erythematosus: New insights into SLE pathogenesis
    • Belot A., & Cimaz R. Monogenic forms of systemic lupus erythematosus: new insights into SLE pathogenesis. Pediatr. Rheumatol. Online J. 10, 21 (2012
    • (2012) Pediatr. Rheumatol. Online J. , vol.10 , pp. 21
    • Belot, A.1    Cimaz, R.2
  • 37
    • 0025666735 scopus 로고
    • Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis
    • Richardson B., et al. Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis. Arthritis Rheum. 33, 1665-1673 (1990
    • (1990) Arthritis Rheum , vol.33 , pp. 1665-1673
    • Richardson, B.1
  • 38
    • 16644397869 scopus 로고    scopus 로고
    • Murine models of lupus induced by hypomethylated T cells
    • Richardson B., Ray D., & Yung R. Murine models of lupus induced by hypomethylated T cells. Methods Mol. Med. 102, 285-294 (2004
    • (2004) Methods Mol. Med , vol.102 , pp. 285-294
    • Richardson, B.1    Ray, D.2    Yung, R.3
  • 39
    • 44849087740 scopus 로고    scopus 로고
    • Defective T cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients
    • Sawalha A. H., et al. Defective T cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients. Genes Immun. 9, 368-378 (2008
    • (2008) Genes Immun , vol.9 , pp. 368-378
    • Sawalha, A.H.1
  • 40
    • 84937516401 scopus 로고    scopus 로고
    • Renal involvement in lupus is characterized by unique DNA methylation changes in naive CD4+ T cells
    • Coit P., et al. Renal involvement in lupus is characterized by unique DNA methylation changes in naive CD4+ T cells. J. Autoimmun. 61, 29-35 (2015
    • (2015) J. Autoimmun , vol.61 , pp. 29-35
    • Coit, P.1
  • 41
    • 84983551816 scopus 로고    scopus 로고
    • Epigenetic reprogramming in naive CD4+ T cells favoring T cell activation and non-TH1 effector T cell immune response as an early event in lupus flares
    • Coit P., et al. Epigenetic reprogramming in naive CD4+ T cells favoring T cell activation and non-TH1 effector T cell immune response as an early event in lupus flares. Arthritis Rheumatol. 68, 2200-2209 (2016
    • (2016) Arthritis Rheumatol , vol.68 , pp. 2200-2209
    • Coit, P.1
  • 42
    • 84860006823 scopus 로고    scopus 로고
    • Dietary and lifestyle factors of DNA methylation
    • Lim U., & Song M. A. Dietary and lifestyle factors of DNA methylation. Methods Mol. Biol. 863, 359-376 (2012
    • (2012) Methods Mol. Biol , vol.863 , pp. 359-376
    • Lim, U.1    Song, M.A.2
  • 43
    • 0036322831 scopus 로고    scopus 로고
    • Maternal methyl supplements in mice affect epigenetic variation and DNA methylation of offspring
    • Cooney C. A., Dave A. A., & Wolff G. L. Maternal methyl supplements in mice affect epigenetic variation and DNA methylation of offspring. J. Nutr. 132, 2393S-2400S (2002
    • (2002) J. Nutr , vol.132 , pp. 2393S-2400S
    • Cooney, C.A.1    Dave, A.A.2    Wolff, G.L.3
  • 44
    • 84960444957 scopus 로고    scopus 로고
    • Increased 5 hydroxymethylcytosine in CD4+ T cells in systemic lupus erythematosus
    • Zhao M., et al. Increased 5 hydroxymethylcytosine in CD4+ T cells in systemic lupus erythematosus. J. Autoimmun. 69, 64-73 (2016
    • (2016) J. Autoimmun , vol.69 , pp. 64-73
    • Zhao, M.1
  • 45
    • 0037330279 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse
    • Mishra N., Reilly C. M., Brown D. R., Ruiz P., & Gilkeson G. S. Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse. J. Clin. Invest. 111, 539-552 (2003
    • (2003) J. Clin. Invest , vol.111 , pp. 539-552
    • Mishra, N.1    Reilly, C.M.2    Brown, D.R.3    Ruiz, P.4    Gilkeson, G.S.5
  • 46
    • 84948462107 scopus 로고    scopus 로고
    • HDAC expression and activity is upregulated in diseased lupus-prone mice
    • Regna N. L., et al. HDAC expression and activity is upregulated in diseased lupus-prone mice. Int. Immunopharmacol. 29, 494-503 (2015
    • (2015) Int. Immunopharmacol , vol.29 , pp. 494-503
    • Regna, N.L.1
  • 47
    • 84947815530 scopus 로고    scopus 로고
    • Specific HDAC6 inhibition by ACY 738 reduces SLE pathogenesis in NZB/W mice
    • Regna N. L., et al. Specific HDAC6 inhibition by ACY 738 reduces SLE pathogenesis in NZB/W mice. Clin. Immunol. 162, 58-73 (2016
    • (2016) Clin. Immunol , vol.162 , pp. 58-73
    • Regna, N.L.1
  • 48
    • 0037441885 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: A new class of immunosuppressors targeting a novel signal pathway essential for CD154 expression
    • Skov S., et al. Histone deacetylase inhibitors: a new class of immunosuppressors targeting a novel signal pathway essential for CD154 expression. Blood 101, 1430-1438 (2003
    • (2003) Blood , vol.101 , pp. 1430-1438
    • Skov, S.1
  • 49
    • 84928340468 scopus 로고    scopus 로고
    • The effect of mycophenolic acid on epigenetic modifications in lupus CD4+ T cells
    • Yang Y., et al. The effect of mycophenolic acid on epigenetic modifications in lupus CD4+ T cells. Clin. Immunol. 158, 67-76 (2015
    • (2015) Clin. Immunol , vol.158 , pp. 67-76
    • Yang, Y.1
  • 50
    • 77649340053 scopus 로고    scopus 로고
    • Global H4 acetylation analysis by ChIP-chip in systemic lupus erythematosus monocytes
    • Zhang Z., Song L., Maurer K., Petri M. A., & Sullivan K. E. Global H4 acetylation analysis by ChIP-chip in systemic lupus erythematosus monocytes. Genes Immun. 11, 124-133 (2010
    • (2010) Genes Immun , vol.11 , pp. 124-133
    • Zhang, Z.1    Song, L.2    Maurer, K.3    Petri, M.A.4    Sullivan, K.E.5
  • 51
    • 84878361920 scopus 로고    scopus 로고
    • Genome-wide qDNA ethylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naive CD4+ T cells from lupus patients
    • Coit P., et al. Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naive CD4+ T cells from lupus patients. J. Autoimmun. 43, 78-84 (2013
    • (2013) J. Autoimmun , vol.43 , pp. 78-84
    • Coit, P.1
  • 52
    • 84923640030 scopus 로고    scopus 로고
    • Interferon regulatory factor 1 marks activated genes and can induce target gene expression in systemic lupus erythematosus
    • Zhang Z., et al. Interferon regulatory factor 1 marks activated genes and can induce target gene expression in systemic lupus erythematosus. Arthritis Rheumatol. 67, 785-796 (2015
    • (2015) Arthritis Rheumatol , vol.67 , pp. 785-796
    • Zhang, Z.1
  • 53
    • 84947597215 scopus 로고    scopus 로고
    • Monocyte enhancers are highly altered in systemic lupus erythematosus
    • Shi L., et al. Monocyte enhancers are highly altered in systemic lupus erythematosus. Epigenomics 7, 921-935 (2015
    • (2015) Epigenomics , vol.7 , pp. 921-935
    • Shi, L.1
  • 54
    • 80052278172 scopus 로고    scopus 로고
    • Monocyte polarization: The relationship of genome-wide changes in H4 acetylation with polarization
    • Zhang Z., Song L., Maurer K., Bagashev A., & Sullivan K. E. Monocyte polarization: the relationship of genome-wide changes in H4 acetylation with polarization. Genes Immun. 12, 445-456 (2011
    • (2011) Genes Immun , vol.12 , pp. 445-456
    • Zhang, Z.1    Song, L.2    Maurer, K.3    Bagashev, A.4    Sullivan, K.E.5
  • 56
    • 84925556593 scopus 로고    scopus 로고
    • BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones
    • Kanno T., et al. BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones. Nat. Struct. Mol. Biol. 21, 1047-1057 (2014
    • (2014) Nat. Struct. Mol. Biol , vol.21 , pp. 1047-1057
    • Kanno, T.1
  • 57
    • 84948439554 scopus 로고    scopus 로고
    • Therapeutic targeting of BET protein BRD4 delays murine lupus
    • Wei S., Sun Y., & Sha H. Therapeutic targeting of BET protein BRD4 delays murine lupus. Int. Immunopharmacol. 29, 314-319 (2015
    • (2015) Int. Immunopharmacol , vol.29 , pp. 314-319
    • Wei, S.1    Sun, Y.2    Sha, H.3
  • 58
    • 38148999355 scopus 로고    scopus 로고
    • Let me count the ways: Mechanisms of gene regulation by miRNAs and siRNAs
    • Wu L., & Belasco J. G. Let me count the ways: mechanisms of gene regulation by miRNAs and siRNAs. Mol. Cell 29, 1-7 (2008
    • (2008) Mol. Cell , vol.29 , pp. 1-7
    • Wu, L.1    Belasco, J.G.2
  • 59
    • 37849031502 scopus 로고    scopus 로고
    • Microarray analysis of microRNA expression in peripheral blood cells of systemic lupus erythematosus patients
    • Dai Y., et al. Microarray analysis of microRNA expression in peripheral blood cells of systemic lupus erythematosus patients. Lupus 16, 939-946 (2007
    • (2007) Lupus , vol.16 , pp. 939-946
    • Dai, Y.1
  • 60
    • 67349211490 scopus 로고    scopus 로고
    • Comprehensive analysis of microRNA expression patterns in renal biopsies of lupus nephritis patients
    • Dai Y., et al. Comprehensive analysis of microRNA expression patterns in renal biopsies of lupus nephritis patients. Rheumatol. Int. 29, 749-754 (2009
    • (2009) Rheumatol. Int , vol.29 , pp. 749-754
    • Dai, Y.1
  • 61
    • 84940112282 scopus 로고    scopus 로고
    • The role of microRNAs and human epidermal growth factor receptor 2 in proliferative lupus nephritis
    • Costa-Reis P., et al. The role of microRNAs and human epidermal growth factor receptor 2 in proliferative lupus nephritis. Arthritis Rheumatol. 67, 2415-2426 (2015
    • (2015) Arthritis Rheumatol , vol.67 , pp. 2415-2426
    • Costa-Reis, P.1
  • 62
    • 84876554579 scopus 로고    scopus 로고
    • Circulating microRNA expression profiles associated with systemic lupus erythematosus
    • Carlsen A. L., et al. Circulating microRNA expression profiles associated with systemic lupus erythematosus. Arthritis Rheum. 65, 1324-1334 (2013
    • (2013) Arthritis Rheum , vol.65 , pp. 1324-1334
    • Carlsen, A.L.1
  • 63
    • 84922461464 scopus 로고    scopus 로고
    • MicroRNA regulation in systemic lupus erythematosus pathogenesis
    • Yan S., Yim L. Y., Lu L., Lau C. S., & Chan V. S. MicroRNA regulation in systemic lupus erythematosus pathogenesis. Immune Netw. 14, 138-148 (2014
    • (2014) Immune Netw , vol.14 , pp. 138-148
    • Yan, S.1    Yim, L.Y.2    Lu, L.3    Lau, C.S.4    Chan, V.S.5
  • 64
    • 84878551158 scopus 로고    scopus 로고
    • MicroRNA 30a promotes B cell hyperactivity in patients with systemic lupus erythematosus by direct interaction with Lyn
    • Liu Y., et al. MicroRNA 30a promotes B cell hyperactivity in patients with systemic lupus erythematosus by direct interaction with Lyn. Arthritis Rheum. 65, 1603-1611 (2013
    • (2013) Arthritis Rheum , vol.65 , pp. 1603-1611
    • Liu, Y.1
  • 65
    • 77953624215 scopus 로고    scopus 로고
    • MicroRNA 21 and microRNA 148a contribute to DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1
    • Pan W., et al. MicroRNA 21 and microRNA 148a contribute to DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1. J. Immunol. 184, 6773-6781 (2010
    • (2010) J. Immunol , vol.184 , pp. 6773-6781
    • Pan, W.1
  • 66
    • 39749163245 scopus 로고    scopus 로고
    • Lymphoproliferative disease and autoimmunity in mice with increased miR 17 92 expression in lymphocytes
    • Xiao C., et al. Lymphoproliferative disease and autoimmunity in mice with increased miR 17 92 expression in lymphocytes. Nat. Immunol. 9, 405-414 (2008
    • (2008) Nat. Immunol , vol.9 , pp. 405-414
    • Xiao, C.1
  • 67
    • 84880767787 scopus 로고    scopus 로고
    • MicroRNAs of the miR 17 approximately 92 family are critical regulators of TFH differentiation
    • Kang S. G., et al. MicroRNAs of the miR 17 approximately 92 family are critical regulators of TFH differentiation. Nat. Immunol. 14, 849-857 (2013
    • (2013) Nat. Immunol , vol.14 , pp. 849-857
    • Kang, S.G.1
  • 68
    • 84890284251 scopus 로고    scopus 로고
    • Deletion of microRNA 155 reduces autoantibody responses and alleviates lupus-like disease in the Faslpr mouse
    • Thai T. H., et al. Deletion of microRNA 155 reduces autoantibody responses and alleviates lupus-like disease in the Faslpr mouse. Proc. Natl Acad. Sci. USA 110, 20194-20199 (2013
    • (2013) Proc. Natl Acad. Sci. USA , vol.110 , pp. 20194-20199
    • Thai, T.H.1
  • 69
    • 79959784552 scopus 로고    scopus 로고
    • Identification of novel microRNA signatures linked to human lupus disease activity and pathogenesis: MiR 21 regulates aberrant T cell responses through regulation of PDCD4 expression
    • Stagakis E., et al. Identification of novel microRNA signatures linked to human lupus disease activity and pathogenesis: miR 21 regulates aberrant T cell responses through regulation of PDCD4 expression. Ann. Rheum. Dis. 70, 1496-1506 (2011
    • (2011) Ann. Rheum. Dis , vol.70 , pp. 1496-1506
    • Stagakis, E.1
  • 70
    • 84884672205 scopus 로고    scopus 로고
    • Using microRNA as an alternative treatment for hyperlipidemia and cardiovascular disease: Cardio-miRs in the pipeline
    • Hennessy E. J., & Moore K. J. Using microRNA as an alternative treatment for hyperlipidemia and cardiovascular disease: cardio-miRs in the pipeline. J. Cardiovasc. Pharmacol. 62, 247-254 (2013
    • (2013) J. Cardiovasc. Pharmacol , vol.62 , pp. 247-254
    • Hennessy, E.J.1    Moore, K.J.2
  • 71
    • 0037451167 scopus 로고    scopus 로고
    • Interferon and granulopoiesis signatures in systemic lupus erythematosus blood
    • Bennett L., et al. Interferon and granulopoiesis signatures in systemic lupus erythematosus blood. J. Exp. Med. 197, 711-723 (2003
    • (2003) J. Exp. Med , vol.197 , pp. 711-723
    • Bennett, L.1
  • 72
    • 0344492212 scopus 로고    scopus 로고
    • Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus
    • Baechler E. C., et al. Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus. Proc. Natl Acad. Sci. USA 100, 2610-2615 (2003
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 2610-2615
    • Baechler, E.C.1
  • 73
    • 10444248118 scopus 로고    scopus 로고
    • Coordinate overexpression of interferon-α induced genes in systemic lupus erythematosus
    • Kirou K. A., et al. Coordinate overexpression of interferon-α induced genes in systemic lupus erythematosus. Arthritis Rheum. 50, 3958-3967 (2004
    • (2004) Arthritis Rheum , vol.50 , pp. 3958-3967
    • Kirou, K.A.1
  • 74
    • 84931009595 scopus 로고    scopus 로고
    • Widely divergent transcriptional patterns between SLE patients of different ancestral backgrounds in sorted immune cell populations
    • Sharma S., et al. Widely divergent transcriptional patterns between SLE patients of different ancestral backgrounds in sorted immune cell populations. J. Autoimmun. 60, 51-58 (2015
    • (2015) J. Autoimmun , vol.60 , pp. 51-58
    • Sharma, S.1
  • 75
    • 79958713761 scopus 로고    scopus 로고
    • A systemic lupus erythematosus gene expression array in disease diagnosis and classification: A preliminary report
    • Juang Y T., et al. A systemic lupus erythematosus gene expression array in disease diagnosis and classification: a preliminary report. Lupus 20 243-249 2011
    • (2011) Lupus , vol.20 , pp. 243-249
    • Juang, Y.T.1
  • 76
    • 84892458522 scopus 로고    scopus 로고
    • A T cell gene expression panel for the diagnosis and monitoring of disease activity in patients with systemic lupus erythematosus
    • Grammatikos A. P., et al. A T cell gene expression panel for the diagnosis and monitoring of disease activity in patients with systemic lupus erythematosus. Clin. Immunol. 150, 192-200 (2014
    • (2014) Clin Immunol , vol.150 , pp. 192-200
    • Grammatikos, A.P.1
  • 77
    • 84952313223 scopus 로고    scopus 로고
    • T cell transcriptomes describe patient subtypes in systemic lupus erythematosus
    • Bradley S J., Suarez-Fueyo A., Moss D. R., Kyttaris V. C., & Tsokos G. C. T cell transcriptomes describe patient subtypes in systemic lupus erythematosus. PLoS ONE 10, e0141171 (2015
    • (2015) Plos One , vol.10 , pp. e0141171
    • Bradley, S.J.1    Suarez-Fueyo, A.2    Moss, D.R.3    Kyttaris, V.C.4    Tsokos, G.C.5
  • 78
    • 84962128086 scopus 로고    scopus 로고
    • Personalized immunomonitoring uncovers molecular networks that stratify lupus patients
    • Banchereau R., et al. Personalized immunomonitoring uncovers molecular networks that stratify lupus patients. Cell 165, 551-565 (2016
    • (2016) Cell , vol.165 , pp. 551-565
    • Banchereau, R.1
  • 79
    • 1042290326 scopus 로고    scopus 로고
    • Cooperation between C1q and DNase i in the clearance of necrotic cell-derived chromatin
    • Gaipl U. S., et al. Cooperation between C1q and DNase I in the clearance of necrotic cell-derived chromatin. Arthritis Rheum. 50, 640-649 (2004
    • (2004) Arthritis Rheum , vol.50 , pp. 640-649
    • Gaipl, U.S.1
  • 80
    • 84859064901 scopus 로고    scopus 로고
    • CRP/anti-CRP antibodies assembly on the surfaces of cell remnants switches their phagocytic clearance toward inflammation
    • Janko C., et al. CRP/anti-CRP antibodies assembly on the surfaces of cell remnants switches their phagocytic clearance toward inflammation. Front. Immunol. 2, 70 (2011
    • (2011) Front. Immunol , vol.2 , pp. 70
    • Janko, C.1
  • 82
    • 82255192363 scopus 로고    scopus 로고
    • Loss of function variant in DNASE1L3 causes a familial form of systemic lupus erythematosus
    • Al Mayouf S. M., et al. Loss of function variant in DNASE1L3 causes a familial form of systemic lupus erythematosus. Nat. Genet. 43, 1186-1188 (2011
    • (2011) Nat. Genet , vol.43 , pp. 1186-1188
    • Al Mayouf, S.M.1
  • 83
    • 84881339076 scopus 로고    scopus 로고
    • Protein kinase Cδ deficiency causes Mendelian systemic lupus erythematosus with B cell-defective apoptosis and hyperproliferation
    • Belot A., et al. Protein kinase Cδ deficiency causes Mendelian systemic lupus erythematosus with B cell-defective apoptosis and hyperproliferation. Arthritis Rheum. 65, 2161-2171 (2013
    • (2013) Arthritis Rheum , vol.65 , pp. 2161-2171
    • Belot, A.1
  • 84
    • 84928822934 scopus 로고    scopus 로고
    • Enhanced activation of dendritic cells by autologous apoptotic microvesicles in MRL/lpr mice
    • Dieker J., et al. Enhanced activation of dendritic cells by autologous apoptotic microvesicles in MRL/lpr mice. Arthritis Res. Ther. 17, 103 (2015
    • (2015) Arthritis Res. Ther , vol.17 , pp. 103
    • Dieker, J.1
  • 85
    • 17844380477 scopus 로고    scopus 로고
    • Spatiotemporal regulation of MyD88-IRF 7 signalling for robust type i interferon induction
    • Honda K., et al. Spatiotemporal regulation of MyD88-IRF 7 signalling for robust type I interferon induction. Nature 434, 1035-1040 (2005
    • (2005) Nature , vol.434 , pp. 1035-1040
    • Honda, K.1
  • 86
    • 29244450802 scopus 로고    scopus 로고
    • Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA
    • Barton G. M., Kagan J. C., & Medzhitov R. Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA. Nat. Immunol. 7, 49-56 (2006
    • (2006) Nat. Immunol , vol.7 , pp. 49-56
    • Barton, G.M.1    Kagan, J.C.2    Medzhitov, R.3
  • 87
    • 42449117483 scopus 로고    scopus 로고
    • Requirement of Toll-like receptor 7 for pristane-induced production of autoantibodies and development of murine lupus nephritis
    • Savarese E., et al. Requirement of Toll-like receptor 7 for pristane-induced production of autoantibodies and development of murine lupus nephritis. Arthritis Rheum. 58, 1107-1115 (2008
    • (2008) Arthritis Rheum , vol.58 , pp. 1107-1115
    • Savarese, E.1
  • 88
    • 34249915031 scopus 로고    scopus 로고
    • Inhibition of Toll-like receptor 7 (TLR 7) or TLR 7 plus TLR 9 attenuates glomerulonephritis and lung injury in experimental lupus
    • Pawar R. D., et al. Inhibition of Toll-like receptor 7 (TLR 7) or TLR 7 plus TLR 9 attenuates glomerulonephritis and lung injury in experimental lupus. J. Am. Soc. Nephrol. 18, 1721-1731 (2007
    • (2007) J. Am. Soc. Nephrol , vol.18 , pp. 1721-1731
    • Pawar, R.D.1
  • 89
    • 33644515263 scopus 로고    scopus 로고
    • Toll-like receptor 7 modulates immune complex glomerulonephritis
    • Pawar R. D., et al. Toll-like receptor 7 modulates immune complex glomerulonephritis. J. Am. Soc. Nephrol. 17, 141-149 (2006
    • (2006) J. Am. Soc. Nephrol , vol.17 , pp. 141-149
    • Pawar, R.D.1
  • 90
    • 33745617886 scopus 로고    scopus 로고
    • A TLR7 translocation accelerates systemic autoimmunity in murine lupus
    • Subramanian S., et al. A TLR7 translocation accelerates systemic autoimmunity in murine lupus. Proc. Natl Acad. Sci. USA 103, 9970-9975 (2006
    • (2006) Proc Natl Acad. Sci. USA , vol.103 , pp. 9970-9975
    • Subramanian, S.1
  • 91
    • 84928543526 scopus 로고    scopus 로고
    • The receptor TREML4 amplifies TLR7 mediated signaling during antiviral responses and autoimmunity
    • Ramirez-Ortiz Z. G., et al. The receptor TREML4 amplifies TLR7 mediated signaling during antiviral responses and autoimmunity. Nat. Immunol. 16, 495-504 (2015
    • (2015) Nat. Immunol , vol.16 , pp. 495-504
    • Ramirez-Ortiz, Z.G.1
  • 92
    • 33750953650 scopus 로고    scopus 로고
    • Expansion of Toll-like receptor 9 expressing B cells in active systemic lupus erythematosus: Implications for the induction and maintenance of the autoimmune process
    • Papadimitraki E. D., et al. Expansion of Toll-like receptor 9 expressing B cells in active systemic lupus erythematosus: implications for the induction and maintenance of the autoimmune process. Arthritis Rheum. 54, 3601-3611 (2006
    • (2006) Arthritis Rheum , vol.54 , pp. 3601-3611
    • Papadimitraki, E.D.1
  • 93
    • 22944490869 scopus 로고    scopus 로고
    • Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus
    • Christensen S. R., et al. Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus. J. Exp. Med. 202, 321-331 (2005
    • (2005) J. Exp. Med , vol.202 , pp. 321-331
    • Christensen, S.R.1
  • 94
    • 79960470158 scopus 로고    scopus 로고
    • Unc93B1 restricts systemic lethal inflammation by orchestrating Toll-like receptor 7 and 9 trafficking
    • Fukui R., et al. Unc93B1 restricts systemic lethal inflammation by orchestrating Toll-like receptor 7 and 9 trafficking. Immunity 35, 69-81 (2011
    • (2011) Immunity , vol.35 , pp. 69-81
    • Fukui, R.1
  • 95
    • 53349178089 scopus 로고    scopus 로고
    • STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
    • Ishikawa H., & Barber G. N. STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. Nature 455, 674-678 (2008
    • (2008) Nature , vol.455 , pp. 674-678
    • Ishikawa, H.1    Barber, G.N.2
  • 96
    • 84980385738 scopus 로고    scopus 로고
    • Discriminating self from non-self in nucleic acid sensing
    • Schlee M., & Hartmann G. Discriminating self from non-self in nucleic acid sensing. Nat. Rev. Immunol. 16, 566-580 (2016
    • (2016) Nat. Rev. Immunol , vol.16 , pp. 566-580
    • Schlee, M.1    Hartmann, G.2
  • 97
    • 84874774951 scopus 로고    scopus 로고
    • Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis inflammation and autoantibody production
    • Molineros J. E., et al. Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis inflammation and autoantibody production. PLoS Genet. 9, e1003222 2013
    • (2013) Plos Genet , vol.9 , pp. e1003222
    • Molineros, J.E.1
  • 98
    • 63649133278 scopus 로고    scopus 로고
    • AIM2 recognizes cytosolic dsDNA and forms a caspase 1 activating inflammasome with ASC
    • Hornung V., et al. AIM2 recognizes cytosolic dsDNA and forms a caspase 1 activating inflammasome with ASC. Nature 458, 514-518 (2009
    • (2009) Nature , vol.458 , pp. 514-518
    • Hornung, V.1
  • 99
    • 84865394537 scopus 로고    scopus 로고
    • Interferon-inducible Ifi200 family genes as modifiers of lupus susceptibility
    • Choubey D. Interferon-inducible Ifi200 family genes as modifiers of lupus susceptibility. Immunol. Lett. 147, 10-17 (2012
    • (2012) Immunol. Lett , vol.147 , pp. 10-17
    • Choubey, D.1
  • 100
    • 84933279572 scopus 로고    scopus 로고
    • Aicardi-Goutières syndrome and the type i interferonopathies
    • Crow Y. J., & Manel N. Aicardi-Goutières syndrome and the type I interferonopathies. Nat. Rev. Immunol. 15, 429-440 (2015
    • (2015) Nat. Rev. Immunol , vol.15 , pp. 429-440
    • Crow, Y.J.1    Manel, N.2
  • 101
    • 84942855451 scopus 로고    scopus 로고
    • Aicardi-Goutières syndrome harbours abundant systemic and brain-reactive autoantibodies
    • Cuadrado E., et al. Aicardi-Goutières syndrome harbours abundant systemic and brain-reactive autoantibodies. Ann. Rheum. Dis. 74, 1931-1939 (2015
    • (2015) Ann. Rheum. Dis , vol.74 , pp. 1931-1939
    • Cuadrado, E.1
  • 102
    • 84962191041 scopus 로고    scopus 로고
    • Altered type II interferon precedes autoantibody accrual and elevated type i interferon activity prior to systemic lupus erythematosus classification
    • Munroe M. E., et al. Altered type II interferon precedes autoantibody accrual and elevated type I interferon activity prior to systemic lupus erythematosus classification. Ann. Rheum. Dis. 75, 2014-2021 (2016
    • (2016) Ann. Rheum. Dis , vol.75 , pp. 2014-2021
    • Munroe, M.E.1
  • 103
    • 84992568338 scopus 로고    scopus 로고
    • Dysregulation of innate and adaptive serum mediators precedes systemic lupus erythematosus classification and improves prognostic accuracy of autoantibodies
    • Lu R., et al. Dysregulation of innate and adaptive serum mediators precedes systemic lupus erythematosus classification and improves prognostic accuracy of autoantibodies. J. Autoimmun. 74, 182-193 (2016
    • (2016) J. Autoimmun , vol.74 , pp. 182-193
    • Lu, R.1
  • 104
    • 84863583259 scopus 로고    scopus 로고
    • Large-scale analysis of tumor necrosis factor α levels in systemic lupus erythematosus
    • Weckerle C. E., et al. Large-scale analysis of tumor necrosis factor α levels in systemic lupus erythematosus. Arthritis Rheum. 64, 2947-2952 (2012
    • (2012) Arthritis Rheum , vol.64 , pp. 2947-2952
    • Weckerle, C.E.1
  • 105
    • 40949123747 scopus 로고    scopus 로고
    • TNF activates an IRF1 dependent autocrine loop leading to sustained expression of chemokines and STAT1 dependent type i interferon-response genes
    • Yarilina A., Park-Min K. H., Antoniv T., Hu X., & Ivashkiv L. B. TNF activates an IRF1 dependent autocrine loop leading to sustained expression of chemokines and STAT1 dependent type I interferon-response genes. Nat. Immunol. 9, 378-387 (2008
    • (2008) Nat. Immunol , vol.9 , pp. 378-387
    • Yarilina, A.1    Park-Min, K.H.2    Antoniv, T.3    Hu, X.4    Ivashkiv, L.B.5
  • 106
    • 84885409854 scopus 로고    scopus 로고
    • IFNα inducible models of murine SLE
    • Liu Z., & Davidson A. IFNα inducible models of murine SLE. Front. Immunol. 4, 306 (2013
    • (2013) Front. Immunol , vol.4 , pp. 306
    • Liu, Z.1    Davidson, A.2
  • 107
    • 84926292764 scopus 로고    scopus 로고
    • Local synthesis of interferon α in lupus nephritis is associated with type i interferons signature and LMP7 induction in renal tubular epithelial cells
    • Castellano G., et al. Local synthesis of interferon α in lupus nephritis is associated with type I interferons signature and LMP7 induction in renal tubular epithelial cells. Arthritis Res. Ther. 17, 72 (2015
    • (2015) Arthritis Res. Ther , vol.17 , pp. 72
    • Castellano, G.1
  • 108
    • 0035403969 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells (natural interferon α/β producing cells) accumulate in cutaneous lupus erythematosus lesions
    • Farkas L., Beiske K., Lund-Johansen F., Brandtzaeg P., & Jahnsen F. L. Plasmacytoid dendritic cells (natural interferon α/β producing cells) accumulate in cutaneous lupus erythematosus lesions. Am. J. Pathol. 159, 237-243 (2001
    • (2001) Am. J. Pathol , vol.159 , pp. 237-243
    • Farkas, L.1    Beiske, K.2    Lund-Johansen, F.3    Brandtzaeg, P.4    Jahnsen, F.L.5
  • 109
    • 50549103097 scopus 로고    scopus 로고
    • Systemic IFN α drives kidney nephritis in B6.Sle123 mice
    • Fairhurst A. M., et al. Systemic IFN α drives kidney nephritis in B6.Sle123 mice. Eur. J. Immunol. 38, 1948-1960 (2008
    • (2008) Eur. J. Immunol , vol.38 , pp. 1948-1960
    • Fairhurst, A.M.1
  • 110
    • 78650765873 scopus 로고    scopus 로고
    • Interferon α accelerates murine systemic lupus erythematosus in a T cell-dependent manner
    • Liu Z., et al. Interferon α accelerates murine systemic lupus erythematosus in a T cell-dependent manner. Arthritis Rheum. 63, 219-229 (2011
    • (2011) Arthritis Rheum , vol.63 , pp. 219-229
    • Liu, Z.1
  • 111
    • 84948419437 scopus 로고    scopus 로고
    • Brief report: Interleukin 38 exerts antiinflammatory functions and is associated with disease activity in systemic lupus erythematosus
    • Rudloff I., et al. Brief report: interleukin 38 exerts antiinflammatory functions and is associated with disease activity in systemic lupus erythematosus. Arthritis Rheumatol. 67, 3219-3225 (2015
    • (2015) Arthritis Rheumatol , vol.67 , pp. 3219-3225
    • Rudloff, I.1
  • 112
    • 54949137275 scopus 로고    scopus 로고
    • Evidence for a pathogenetic role of interleukin 18 in cutaneous lupus erythematosus
    • Wang D., Drenker M., Eiz-Vesper B., Werfel T., & Wittmann M. Evidence for a pathogenetic role of interleukin 18 in cutaneous lupus erythematosus. Arthritis Rheum. 58, 3205-3215 (2008
    • (2008) Arthritis Rheum , vol.58 , pp. 3205-3215
    • Wang, D.1    Drenker, M.2    Eiz-Vesper, B.3    Werfel, T.4    Wittmann, M.5
  • 113
    • 84922065273 scopus 로고    scopus 로고
    • TH1/TH2/TH17/TReg cytokine imbalance in systemic lupus erythematosus (SLE) patients: Correlation with disease activity
    • Talaat R. M., Mohamed S. F., Bassyouni I. H., & Raouf A. A. TH1/TH2/TH17/TReg cytokine imbalance in systemic lupus erythematosus (SLE) patients: correlation with disease activity. Cytokine 72, 146-153 (2015
    • (2015) Cytokine , vol.72 , pp. 146-153
    • Talaat, R.M.1    Mohamed, S.F.2    Bassyouni, I.H.3    Raouf, A.A.4
  • 114
    • 4344718846 scopus 로고    scopus 로고
    • Cyclic adenosine 5′ monophosphate response element modulator is responsible for the decreased expression of c fos and activator protein 1 binding in T cells from patients with systemic lupus erythematosus
    • Kyttaris V. C., Juang Y. T., Tenbrock K., Weinstein A., & Tsokos G. C. Cyclic adenosine 5′ monophosphate response element modulator is responsible for the decreased expression of c fos and activator protein 1 binding in T cells from patients with systemic lupus erythematosus. J. Immunol. 173, 3557-3563 (2004
    • (2004) J. Immunol , vol.173 , pp. 3557-3563
    • Kyttaris, V.C.1    Juang, Y.T.2    Tenbrock, K.3    Weinstein, A.4    Tsokos, G.C.5
  • 115
    • 0035869333 scopus 로고    scopus 로고
    • Molecular basis of deficient IL 2 production in T cells from patients with systemic lupus erythematosus
    • Solomou E. E., Juang Y. T., Gourley M. F., Kammer G. M., & Tsokos G. C. Molecular basis of deficient IL 2 production in T cells from patients with systemic lupus erythematosus. J. Immunol. 166, 4216-4222 (2001
    • (2001) J. Immunol , vol.166 , pp. 4216-4222
    • Solomou, E.E.1    Juang, Y.T.2    Gourley, M.F.3    Kammer, G.M.4    Tsokos, G.C.5
  • 116
    • 84879407426 scopus 로고    scopus 로고
    • Treatment with anti-interleukin 23 antibody ameliorates disease in lupus-prone mice
    • Kyttaris V. C., Kampagianni O., & Tsokos G. C. Treatment with anti-interleukin 23 antibody ameliorates disease in lupus-prone mice. Biomed. Res. Int. 2013, 861028 (2013
    • (2013) Biomed. Res. Int , vol.2013 , pp. 861028
    • Kyttaris, V.C.1    Kampagianni, O.2    Tsokos, G.C.3
  • 117
    • 23744476832 scopus 로고    scopus 로고
    • BAFF overexpression is associated with autoantibody production in autoimmune diseases
    • Pers J. O., et al. BAFF overexpression is associated with autoantibody production in autoimmune diseases. Ann. NY Acad. Sci. 1050, 34-39 (2005
    • (2005) Ann. NY Acad. Sci , vol.1050 , pp. 34-39
    • Pers, J.O.1
  • 118
    • 22244484101 scopus 로고    scopus 로고
    • BAFF overexpression and accelerated glomerular disease in mice with an incomplete genetic predisposition to systemic lupus erythematosus
    • Stohl W., et al. BAFF overexpression and accelerated glomerular disease in mice with an incomplete genetic predisposition to systemic lupus erythematosus. Arthritis Rheum. 52, 2080-2091 (2005
    • (2005) Arthritis Rheum , vol.52 , pp. 2080-2091
    • Stohl, W.1
  • 119
    • 79960918034 scopus 로고    scopus 로고
    • BAFF and selection of autoreactive B cells
    • Liu Z., & Davidson A. BAFF and selection of autoreactive B cells. Trends Immunol. 32, 388-394 (2011
    • (2011) Trends Immunol , vol.32 , pp. 388-394
    • Liu, Z.1    Davidson, A.2
  • 120
    • 84885090679 scopus 로고    scopus 로고
    • Elevated serum BAFF levels are associated with rising anti-double-stranded DNA antibody levels and disease flare following B cell depletion therapy in systemic lupus erythematosus
    • Carter L. M., Isenberg D. A., & Ehrenstein M. R. Elevated serum BAFF levels are associated with rising anti-double-stranded DNA antibody levels and disease flare following B cell depletion therapy in systemic lupus erythematosus. Arthritis Rheum. 65, 2672-2679 (2013
    • (2013) Arthritis Rheum , vol.65 , pp. 2672-2679
    • Carter, L.M.1    Isenberg, D.A.2    Ehrenstein, M.R.3
  • 121
    • 79957805027 scopus 로고    scopus 로고
    • After half-century?s wait approval paves path for new lupus drugs
    • Ledford H. After half-century?s wait approval paves path for new lupus drugs. Nat. Med. 17, 400 (2011
    • (2011) Nat. Med , vol.17 , pp. 400
    • Ledford, H.1
  • 122
    • 82455198794 scopus 로고    scopus 로고
    • A phase III randomized placebo-controlled study of belimumab a monoclonal antibody that inhibits B lymphocyte stimulator in patients with systemic lupus erythematosus
    • Furie R., et al. A phase III randomized placebo-controlled study of belimumab a monoclonal antibody that inhibits B lymphocyte stimulator in patients with systemic lupus erythematosus. Arthritis Rheum. 63, 3918-3930 2011
    • (2011) Arthritis Rheum , vol.63 , pp. 3918-3930
    • Furie, R.1
  • 123
    • 79952070370 scopus 로고    scopus 로고
    • Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: A randomised placebo-controlled phase 3 trial
    • Navarra S. V., et al. Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised placebo-controlled phase 3 trial. Lancet 377, 721-731 (2011
    • (2011) Lancet , vol.377 , pp. 721-731
    • Navarra, S.V.1
  • 124
    • 48249107477 scopus 로고    scopus 로고
    • Systemic lupus erythematosus patients have increased number of circulating plasmacytoid dendritic cells but decreased myeloid dendritic cells with deficient CD83 expression
    • Jin O., et al. Systemic lupus erythematosus patients have increased number of circulating plasmacytoid dendritic cells but decreased myeloid dendritic cells with deficient CD83 expression. Lupus 17, 654-662 (2008
    • (2008) Lupus , vol.17 , pp. 654-662
    • Jin, O.1
  • 125
    • 0032586001 scopus 로고    scopus 로고
    • FcγRII (CD32)-dependent induction of interferon α by serum from patients with lupus erythematosus
    • Batteux F., Palmer P., Daeron M., Weill B., & Lebon P. FcγRII (CD32)-dependent induction of interferon α by serum from patients with lupus erythematosus. Eur. Cytokine Netw. 10, 509-514 (1999
    • (1999) Eur. Cytokine Netw , vol.10 , pp. 509-514
    • Batteux, F.1    Palmer, P.2    Daeron, M.3    Weill, B.4    Lebon, P.5
  • 126
    • 50849135184 scopus 로고    scopus 로고
    • Active systemic lupus erythematosus is associated with failure of antigen-presenting cells to express programmed death ligand 1
    • Mozaffarian N., Wiedeman A. E., & Stevens A. M. Active systemic lupus erythematosus is associated with failure of antigen-presenting cells to express programmed death ligand 1. Rheumatology (Oxford) 47, 1335-1341 (2008
    • (2008) Rheumatology (Oxford , vol.47 , pp. 1335-1341
    • Mozaffarian, N.1    Wiedeman, A.E.2    Stevens, A.M.3
  • 127
    • 84984977910 scopus 로고    scopus 로고
    • Activated T cells enhance interferon α production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes
    • Leonard D., et al. Activated T cells enhance interferon α production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes. Ann. Rheum. Dis. 75, 1728-1734 (2015
    • (2015) Ann. Rheum. Dis , vol.75 , pp. 1728-1734
    • Leonard, D.1
  • 128
    • 84946762351 scopus 로고    scopus 로고
    • RNA sensing by conventional dendritic cells is central to the development of lupus nephritis
    • Celhar T., et al. RNA sensing by conventional dendritic cells is central to the development of lupus nephritis. Proc. Natl Acad. Sci. USA 112, E6195-E6204 2015
    • (2015) Proc. Natl Acad. Sci. USA , vol.112 , pp. E6195-E6204
    • Celhar, T.1
  • 129
    • 84874434432 scopus 로고    scopus 로고
    • Impaired phagocytosis and susceptibility to infection in pediatric-onset systemic lupus erythematosus
    • Wu S. A., et al. Impaired phagocytosis and susceptibility to infection in pediatric-onset systemic lupus erythematosus. Lupus 22, 279-288 (2013
    • (2013) Lupus , vol.22 , pp. 279-288
    • Wu, S.A.1
  • 130
    • 84903134145 scopus 로고    scopus 로고
    • Low production of reactive oxygen species in granulocytes is associated with organ damage in systemic lupus erythematosus
    • Bengtsson A. A., et al. Low production of reactive oxygen species in granulocytes is associated with organ damage in systemic lupus erythematosus. Arthritis Res. Ther. 16, R120 2014
    • (2014) Arthritis Res. Ther , vol.16 , pp. R120
    • Bengtsson, A.A.1
  • 131
    • 57149129432 scopus 로고    scopus 로고
    • Chronic granulomatous disease as a risk factor for autoimmune disease
    • De Ravin S. S., et al. Chronic granulomatous disease as a risk factor for autoimmune disease. J. Allergy Clin. Immunol. 122, 1097-1103 (2008
    • (2008) J. Allergy Clin. Immunol , vol.122 , pp. 1097-1103
    • De Ravin, S.S.1
  • 132
    • 85027940542 scopus 로고    scopus 로고
    • Inflammatory manifestations in a single-center cohort of patients with chronic granulomatous disease
    • Magnani A., et al. Inflammatory manifestations in a single-center cohort of patients with chronic granulomatous disease. J. Allergy Clin. Immunol. 134, 655-662 (2014
    • (2014) J. Allergy Clin. Immunol , vol.134 , pp. 655-662
    • Magnani, A.1
  • 133
    • 84868020491 scopus 로고    scopus 로고
    • NADPH oxidase inhibits the pathogenesis of systemic lupus erythematosus
    • 157ra141
    • Campbell A. M., Kashgarian M., & Shlomchik M. J. NADPH oxidase inhibits the pathogenesis of systemic lupus erythematosus. Sci. Transl Med. 4, 157ra141 (2012
    • (2012) Sci. Transl Med , vol.4
    • Campbell, A.M.1    Kashgarian, M.2    Shlomchik, M.J.3
  • 134
    • 84913594061 scopus 로고    scopus 로고
    • Reactive oxygen species deficiency induces autoimmunity with type 1 interferon signature
    • Kelkka T., et al. Reactive oxygen species deficiency induces autoimmunity with type 1 interferon signature. Antioxid. Redox Signal. 21, 2231-2245 (2014
    • (2014) Antioxid. Redox Signal , vol.21 , pp. 2231-2245
    • Kelkka, T.1
  • 135
    • 84957441476 scopus 로고    scopus 로고
    • Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease
    • Lood C., et al. Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease. Nat. Med. 22, 146-153 (2016
    • (2016) Nat. Med , vol.22 , pp. 146-153
    • Lood, C.1
  • 136
    • 31544436673 scopus 로고    scopus 로고
    • Abnormal apoptosis in chronic granulomatous disease and autoantibody production characteristic of lupus
    • Sanford A. N., Suriano A. R., Herche D., Dietzmann K., & Sullivan K. E. Abnormal apoptosis in chronic granulomatous disease and autoantibody production characteristic of lupus. Rheumatology (Oxford) 45, 178-181 (2006
    • (2006) Rheumatology (Oxford , vol.45 , pp. 178-181
    • Sanford, A.N.1    Suriano, A.R.2    Herche, D.3    Dietzmann, K.4    Sullivan, K.E.5
  • 137
    • 79960392810 scopus 로고    scopus 로고
    • Netting neutrophils induce endothelial damage infiltrate tissues and expose immunostimulatory molecules in systemic lupus erythematosus
    • Villanueva E., et al. Netting neutrophils induce endothelial damage infiltrate tissues and expose immunostimulatory molecules in systemic lupus erythematosus. J. Immunol. 187, 538-552 (2011
    • (2011) J. Immunol , vol.187 , pp. 538-552
    • Illanueva, E.1
  • 138
    • 84942570773 scopus 로고    scopus 로고
    • The role of neutrophils in the pathogenesis of systemic lupus erythematosus
    • Smith C. K., & Kaplan M. J. The role of neutrophils in the pathogenesis of systemic lupus erythematosus. Curr. Opin. Rheumatol. 27, 448-453 (2015
    • (2015) Curr. Opin. Rheumatol , vol.27 , pp. 448-453
    • Smith, C.K.1    Kaplan, M.J.2
  • 139
    • 79952476762 scopus 로고    scopus 로고
    • Netting neutrophils are major inducers of type i IFN production in pediatric systemic lupus erythematosus
    • Garcia-Romo G. S., et al. Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus. Sci. Transl Med. 3, 73ra20 (2011
    • (2011) Sci. Transl Med , vol.3 , pp. 73ra20
    • Garcia-Romo, G.S.1
  • 140
    • 79952468782 scopus 로고    scopus 로고
    • Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes in systemic lupus erythematosus
    • 73ra19
    • Lande R., et al. Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes in systemic lupus erythematosus. Sci. Transl Med. 3, 73ra19 (2011
    • (2011) Sci. Transl Med , vol.3
    • Lande, R.1
  • 141
    • 84957447776 scopus 로고    scopus 로고
    • Single-cell systems-level analysis of human Toll-like receptor activation defines a chemokine signature in patients with systemic lupus erythematosus
    • O?Gorman W. E., et al. Single-cell systems-level analysis of human Toll-like receptor activation defines a chemokine signature in patients with systemic lupus erythematosus. J. Allergy Clin. Immunol. 136, 1326-1336 (2015
    • (2015) J. Allergy Clin. Immunol , vol.136 , pp. 1326-1336
    • O'Gorman, W.E.1
  • 142
    • 0035188299 scopus 로고    scopus 로고
    • Predictive power of the second renal biopsy in lupus nephritis: Significance of macrophages
    • Hill G. S., et al. Predictive power of the second renal biopsy in lupus nephritis: significance of macrophages. Kidney Int. 59, 304-316 (2001
    • (2001) Kidney Int , vol.59 , pp. 304-316
    • Hill, G.S.1
  • 143
    • 0347922145 scopus 로고    scopus 로고
    • Premature coronary-artery atherosclerosis in systemic lupus erythematosus
    • Asanuma Y., et al. Premature coronary-artery atherosclerosis in systemic lupus erythematosus. N. Engl. J. Med. 349, 2407-2415 (2003
    • (2003) N. Engl. J. Med , vol.349 , pp. 2407-2415
    • Asanuma, Y.1
  • 144
    • 84946542731 scopus 로고    scopus 로고
    • Significance of CD163 positive macrophages in proliferative glomerulonephritis
    • Li J., Liu C. H., Xu D. L., & Gao B. Significance of CD163 positive macrophages in proliferative glomerulonephritis. Am. J. Med. Sci. 350, 387-392 (2015
    • (2015) Am. J. Med. Sci , vol.350 , pp. 387-392
    • Li, J.1    Liu, C.H.2    Xu, D.L.3    Gao, B.4
  • 145
    • 84955212444 scopus 로고    scopus 로고
    • Monoclonal antibody against macrophage colony-stimulating factor suppresses circulating monocytes and tissue macrophage function but does not alter cell infiltration/activation in cutaneous lesions or clinical outcomes in patients with cutaneous lupus erythematosus
    • Masek-Hammerman K., et al. Monoclonal antibody against macrophage colony-stimulating factor suppresses circulating monocytes and tissue macrophage function but does not alter cell infiltration/activation in cutaneous lesions or clinical outcomes in patients with cutaneous lupus erythematosus. Clin. Exp. Immunol. 183, 258-270 (2016
    • (2016) Clin. Exp. Immunol , vol.183 , pp. 258-270
    • Masek-Hammerman, K.1
  • 146
    • 20444364910 scopus 로고    scopus 로고
    • Genetic determination of T cell help in loss of tolerance to nuclear antigens
    • Chen Y., Cuda C., & Morel L. Genetic determination of T cell help in loss of tolerance to nuclear antigens. J. Immunol. 174, 7692-7702 (2005
    • (2005) J. Immunol , vol.174 , pp. 7692-7702
    • Chen, Y.1    Cuda, C.2    Morel, L.3
  • 147
    • 81755184312 scopus 로고    scopus 로고
    • Regulatory T cells in systemic lupus erythematosus and rheumatoid arthritis
    • Chavele K. M., & Ehrenstein M. R. Regulatory T cells in systemic lupus erythematosus and rheumatoid arthritis. FEBS Lett. 585, 3603-3610 (2011
    • (2011) FEBS Lett , vol.585 , pp. 3603-3610
    • Chavele, K.M.1    Ehrenstein, M.R.2
  • 148
    • 16844376445 scopus 로고    scopus 로고
    • Systemic lupus erythematosus serum IgG increases CREM binding to the IL 2 promoter and suppresses IL 2 production through CaMKIV
    • Juang Y. T., et al. Systemic lupus erythematosus serum IgG increases CREM binding to the IL 2 promoter and suppresses IL 2 production through CaMKIV. J. Clin. Invest. 115, 996-1005 (2005
    • (2005) J. Clin. Invest , vol.115 , pp. 996-1005
    • Juang, Y.T.1
  • 149
    • 0034744286 scopus 로고    scopus 로고
    • Fc ϵ receptor type i γ chain replaces the deficient T cell receptor ζ chain in T cells of patients with systemic lupus erythematosus
    • Enyedy E. J., et al. Fc ϵ receptor type I γ chain replaces the deficient T cell receptor ζ chain in T cells of patients with systemic lupus erythematosus. Arthritis Rheum. 44, 1114-1121 (2001
    • (2001) Arthritis Rheum , vol.44 , pp. 1114-1121
    • Enyedy, E.J.1
  • 150
    • 0032036481 scopus 로고    scopus 로고
    • Altered pattern of TCR/CD3 mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythematosus deficient expression of the T cell receptor ζ chain
    • Liossis S. N., Ding X. Z., Dennis G. J., & Tsokos G. C. Altered pattern of TCR/CD3 mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythematosus. Deficient expression of the T cell receptor ζ chain. J. Clin. Invest. 101, 1448-1457 (1998
    • (1998) J. Clin. Invest , vol.101 , pp. 1448-1457
    • Liossis, S.N.1    Ding, X.Z.2    Dennis, G.J.3    Tsokos, G.C.4
  • 151
    • 61449084536 scopus 로고    scopus 로고
    • Activation of mammalian target of rapamycin controls the loss of TCRζ in lupus T cells through HRES 1/Rab4 regulated lysosomal degradation
    • Fernandez D. R., et al. Activation of mammalian target of rapamycin controls the loss of TCRζ in lupus T cells through HRES 1/Rab4 regulated lysosomal degradation. J. Immunol. 182, 2063-2073 (2009
    • (2009) J. Immunol , vol.182 , pp. 2063-2073
    • Fernandez, D.R.1
  • 152
    • 58849162766 scopus 로고    scopus 로고
    • Expanded double negative T cells in patients with systemic lupus erythematosus produce IL 17 and infiltrate the kidneys
    • Crispin J. C., et al. Expanded double negative T cells in patients with systemic lupus erythematosus produce IL 17 and infiltrate the kidneys. J. Immunol. 181, 8761-8766 (2008
    • (2008) J. Immunol , vol.181 , pp. 8761-8766
    • Crispin, J.C.1
  • 153
    • 84940960375 scopus 로고    scopus 로고
    • Increased expression of TLR2 in CD4+ T cells from SLE patients enhances immune reactivity and promotes IL 17 expression through histone modifications
    • Liu Y., et al. Increased expression of TLR2 in CD4+ T cells from SLE patients enhances immune reactivity and promotes IL 17 expression through histone modifications. Eur. J. Immunol. 45, 2683-2693 (2015
    • (2015) Eur. J. Immunol , vol.45 , pp. 2683-2693
    • Liu, Y.1
  • 154
    • 79953323051 scopus 로고    scopus 로고
    • IL 17 producing T cells in lupus nephritis
    • Apostolidis S. A., Crispin J. C., & Tsokos G. C. IL 17 producing T cells in lupus nephritis. Lupus 20, 120-124 (2011
    • (2011) Lupus , vol.20 , pp. 120-124
    • Apostolidis, S.A.1    Crispin, J.C.2    Tsokos, G.C.3
  • 155
    • 70449719356 scopus 로고    scopus 로고
    • Human TCR αβ+ CD4- CD8- T cells can derive from CD8+ T cells and display an inflammatory effector phenotype
    • Crispin J. C., & Tsokos G. C. Human TCR αβ+ CD4- CD8- T cells can derive from CD8+ T cells and display an inflammatory effector phenotype. J. Immunol. 183, 4675-4681 (2009
    • (2009) J. Immunol , vol.183 , pp. 4675-4681
    • Crispin, J.C.1    Tsokos, G.C.2
  • 156
    • 0024341842 scopus 로고
    • T cell receptor α/β expressing double-negative (CD4-/CD8-) and CD4+ T helper cells in humans augment the production of pathogenic anti-DNA autoantibodies associated with lupus nephritis
    • Shivakumar S., Tsokos G. C., & Datta S. K. T cell receptor α/β expressing double-negative (CD4-/CD8-) and CD4+ T helper cells in humans augment the production of pathogenic anti-DNA autoantibodies associated with lupus nephritis. J. Immunol. 143, 103-112 1989
    • (1989) J. Immunol , vol.143 , pp. 103-112
    • Shivakumar, S.1    Tsokos, G.C.2    Datta, S.K.3
  • 157
    • 0033532630 scopus 로고    scopus 로고
    • MRL-lpr/lpr mice exhibit a defect in maintaining developmental arrest and follicular exclusion of anti-double-stranded DNA B cells
    • Mandik-Nayak L., et al. MRL-lpr/lpr mice exhibit a defect in maintaining developmental arrest and follicular exclusion of anti-double-stranded DNA B cells. J. Exp. Med. 189, 1799-1814 (1999
    • (1999) J. Exp. Med , vol.189 , pp. 1799-1814
    • Mandik-Nayak, L.1
  • 158
    • 84924302055 scopus 로고    scopus 로고
    • T/B cell interactions are more transient in response to weak stimuli in SLE-prone mice
    • Sinai P., et al. T/B cell interactions are more transient in response to weak stimuli in SLE-prone mice. Eur. J. Immunol. 44, 3522-3531 (2014
    • (2014) Eur J. Immunol , vol.44 , pp. 3522-3531
    • Sinai, P.1
  • 159
    • 47749123498 scopus 로고    scopus 로고
    • Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors
    • Mietzner B., et al. Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors. Proc. Natl Acad. Sci. USA 105, 9727-9732 (2008
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 9727-9732
    • Mietzner, B.1
  • 160
    • 84881172662 scopus 로고    scopus 로고
    • Expansion of an osteopontin-expressing T follicular helper cell subset correlates with autoimmunity in B6.Sle1b mice and is suppressed by the H1 isoform of the Slamf6 receptor
    • Keszei M., et al. Expansion of an osteopontin-expressing T follicular helper cell subset correlates with autoimmunity in B6.Sle1b mice and is suppressed by the H1 isoform of the Slamf6 receptor. FASEB J. 27, 3123-3131 (2013
    • (2013) FASEB J. , vol.27 , pp. 3123-3131
    • Keszei, M.1
  • 161
    • 84876513517 scopus 로고    scopus 로고
    • T follicular helper cells mediate expansion of regulatory B cells via IL 21 in lupus-prone MRL/lpr mice
    • Yang X., et al T follicular helper cells mediate expansion of regulatory B cells via IL 21 in lupus-prone MRL/lpr mice. PLoS ONE 8, e62855 2013
    • (2013) Plos One , vol.8 , pp. e62855
    • Yang, X.1
  • 162
    • 84925762443 scopus 로고    scopus 로고
    • Circulating follicular helper-like T cells in systemic lupus erythematosus: Association with disease activity
    • Choi J. Y., et al. Circulating follicular helper-like T cells in systemic lupus erythematosus: association with disease activity. Arthritis Rheumatol. 67, 988-999 (2015
    • (2015) Arthritis Rheumatol , vol.67 , pp. 988-999
    • Choi, J.Y.1
  • 163
    • 84996487741 scopus 로고    scopus 로고
    • A comprehensive investigation on the distribution of circulating follicular t helper cells and b cell subsets in primary sjögren?s syndrome and systemic lupus erythematosus
    • Szabo K., Papp G., Szanto A., Tarr T., & Zeher M. A comprehensive investigation on the distribution of circulating follicular T helper cells and B cell subsets in primary Sjögren?s syndrome and systemic lupus erythematosus. Clin. Exp. Immunol. (2015
    • (2015) Clin Exp. Immunol
    • Szabo, K.1    Papp, G.2    Szanto, A.3    Tarr, T.4    Zeher, M.5
  • 164
    • 84884367704 scopus 로고    scopus 로고
    • Circulating TFH subset distribution is strongly affected in lupus patients with an active disease
    • Le Coz C., et al. Circulating TFH subset distribution is strongly affected in lupus patients with an active disease. PLoS ONE 8, e75319 (2013
    • (2013) Plos One , vol.8 , pp. e75319
    • Le Coz, C.1
  • 165
    • 84899112642 scopus 로고    scopus 로고
    • Cell distance mapping identifies functional T follicular helper cells in inflamed human renal tissue
    • Liarski V. M., et al. Cell distance mapping identifies functional T follicular helper cells in inflamed human renal tissue. Sci. Transl Med. 6, 230ra46 (2014
    • (2014) Sci. Transl Med , vol.6 , pp. 230ra46
    • Liarski, V.M.1
  • 166
    • 74849138095 scopus 로고    scopus 로고
    • Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus
    • Simpson N., et al. Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus. Arthritis Rheum. 62, 234-244 (2010
    • (2010) Arthritis Rheum , vol.62 , pp. 234-244
    • Simpson, N.1
  • 167
    • 84937641822 scopus 로고    scopus 로고
    • OX40 ligand contributes to human lupus pathogenesis by promoting T follicular helper response
    • Jacquemin C., et al. OX40 ligand contributes to human lupus pathogenesis by promoting T follicular helper response. Immunity 42, 1159-1170 (2015
    • (2015) Immunity , vol.42 , pp. 1159-1170
    • Jacquemin, C.1
  • 168
    • 84992071354 scopus 로고    scopus 로고
    • Low-dose interleukin 2 selectively corrects regulatory T cell defects in patients with systemic lupus erythematosus
    • von Spee-Mayer C., et al. Low-dose interleukin 2 selectively corrects regulatory T cell defects in patients with systemic lupus erythematosus. Ann. Rheum. Dis. (2015
    • (2015) Ann. Rheum. Dis
    • Von Spee-Mayer, C.1
  • 169
    • 78650014073 scopus 로고    scopus 로고
    • Abnormalities of B cell subsets in patients with systemic lupus erythematosus
    • Dörner T., Jacobi A. M., Lee J., & Lipsky P. E. Abnormalities of B cell subsets in patients with systemic lupus erythematosus. J. Immunol. Methods 363, 187-197 (2011
    • (2011) J. Immunol. Methods , vol.363 , pp. 187-197
    • Dörner, T.1    Jacobi, A.M.2    Lee, J.3    Lipsky, P.E.4
  • 170
    • 84865400741 scopus 로고    scopus 로고
    • TLR9 drives the development of transitional B cells towards the marginal zone pathway and promotes autoimmunity
    • Guerrier T., Youinou P., Pers J. O., & Jamin C. TLR9 drives the development of transitional B cells towards the marginal zone pathway and promotes autoimmunity. J. Autoimmun. 39, 173-179 (2012
    • (2012) J. Autoimmun , vol.39 , pp. 173-179
    • Guerrier, T.1    Youinou, P.2    Pers, J.O.3    Jamin, C.4
  • 171
    • 2942518502 scopus 로고    scopus 로고
    • Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches
    • Thien M., et al. Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches. Immunity 20, 785-798 (2004
    • (2004) Immunity , vol.20 , pp. 785-798
    • Thien, M.1
  • 172
    • 1842633887 scopus 로고    scopus 로고
    • Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF
    • Lesley R., et al. Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF. Immunity 20, 441-453 (2004
    • (2004) Immunity , vol.20 , pp. 441-453
    • Lesley, R.1
  • 173
    • 0033428703 scopus 로고    scopus 로고
    • Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations
    • Mackay F., et al. Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J. Exp. Med. 190, 1697-1710 (1999
    • (1999) J. Exp. Med , vol.190 , pp. 1697-1710
    • Mackay, F.1
  • 174
    • 0142009533 scopus 로고    scopus 로고
    • Development of autoantibodies before the clinical onset of systemic lupus erythematosus
    • Arbuckle M. R., et al. Development of autoantibodies before the clinical onset of systemic lupus erythematosus. N. Engl. J. Med. 349, 1526-1533 (2003
    • (2003) N. Engl. J. Med , vol.349 , pp. 1526-1533
    • Arbuckle, M.R.1
  • 175
    • 0041689676 scopus 로고    scopus 로고
    • Predominant autoantibody production by early human B cell precursors
    • Wardemann H., et al. Predominant autoantibody production by early human B cell precursors. Science 301, 1374-1377 (2003
    • (2003) Science , vol.301 , pp. 1374-1377
    • Wardemann, H.1
  • 176
    • 0034669990 scopus 로고    scopus 로고
    • Disturbed peripheral B lymphocyte homeostasis in systemic lupus erythematosus
    • Odendahl M., et al. Disturbed peripheral B lymphocyte homeostasis in systemic lupus erythematosus. J. Immunol. 165, 5970-5979 (2000
    • (2000) J. Immunol , vol.165 , pp. 5970-5979
    • Odendahl, M.1
  • 177
    • 84908371398 scopus 로고    scopus 로고
    • Impaired suppressive capacity of activation-induced regulatory B cells in systemic lupus erythematosus
    • Gao N., et al. Impaired suppressive capacity of activation-induced regulatory B cells in systemic lupus erythematosus. Arthritis Rheumatol. 66, 2849-2861 (2014
    • (2014) Arthritis Rheumatol , vol.66 , pp. 2849-2861
    • Gao, N.1
  • 179
    • 0031571270 scopus 로고    scopus 로고
    • Autoantibodies to ribosomal P proteins penetrate into live hepatocytes and cause cellular dysfunction in culture
    • Koscec M., et al. Autoantibodies to ribosomal P proteins penetrate into live hepatocytes and cause cellular dysfunction in culture. J. Immunol. 159, 2033-2041 (1997
    • (1997) J. Immunol , vol.159 , pp. 2033-2041
    • Koscec, M.1
  • 180
    • 84944810495 scopus 로고    scopus 로고
    • The Ro60 autoantigen binds endogenous retroelements and regulates inflammatory gene expression
    • Hung T., et al. The Ro60 autoantigen binds endogenous retroelements and regulates inflammatory gene expression. Science 350, 455-459 (2015
    • (2015) Science , vol.350 , pp. 455-459
    • Hung, T.1
  • 181
    • 84929192209 scopus 로고    scopus 로고
    • High affinity antibodies against influenza characterize the plasmablast response in SLE patients after vaccination
    • Kaur K., et al. High affinity antibodies against influenza characterize the plasmablast response in SLE patients after vaccination. PLoS ONE 10, e0125618 2015
    • (2015) Plos One , vol.10 , pp. e0125618
    • Kaur, K.1
  • 182
    • 84896518122 scopus 로고    scopus 로고
    • Autoreactive IgE is prevalent in systemic lupus erythematosus and is associated with increased disease activity and nephritis
    • Dema B., et al. Autoreactive IgE is prevalent in systemic lupus erythematosus and is associated with increased disease activity and nephritis. PLoS ONE 9, e90424 2014
    • (2014) Plos One , vol.9 , pp. e90424
    • Dema, B.1
  • 183
    • 84955188359 scopus 로고    scopus 로고
    • Self-reactive IgE exacerbates interferon responses associated with autoimmunity
    • Henault J., et al. Self-reactive IgE exacerbates interferon responses associated with autoimmunity. Nat. Immunol. 17, 196-203 (2016
    • (2016) Nat. Immunol , vol.17 , pp. 196-203
    • Henault, J.1
  • 184
    • 84870462253 scopus 로고    scopus 로고
    • Increased IgE serum levels are unrelated to allergic and parasitic diseases in patients with juvenile systemic lupus erythematosus
    • Liphaus B. L., Jesus A. A., Silva C. A., Coutinho A., & Carneiro-Sampaio M. Increased IgE serum levels are unrelated to allergic and parasitic diseases in patients with juvenile systemic lupus erythematosus. Clinics (São Paulo) 67, 1275-1280 (2012
    • (2012) Clinics (São Paulo , vol.67 , pp. 1275-1280
    • Liphaus, B.L.1    Jesus, A.A.2    Silva, C.A.3    Coutinho, A.4    Carneiro-Sampaio, M.5
  • 185
    • 77953212872 scopus 로고    scopus 로고
    • Basophils and the T helper 2 environment can promote the development of lupus nephritis
    • Charles N., Hardwick D., Daugas E., Illei G. G., & Rivera J. Basophils and the T helper 2 environment can promote the development of lupus nephritis. Nat. Med. 16, 701-707 (2010
    • (2010) Nat. Med , vol.16 , pp. 701-707
    • Charles, N.1    Hardwick, D.2    Daugas, E.3    Illei, G.G.4    Rivera, J.5
  • 186
    • 64049085018 scopus 로고    scopus 로고
    • Lyn kinase controls basophil GATA 3 transcription factor expression and induction of TH2 cell differentiation
    • Charles N., et al. Lyn kinase controls basophil GATA 3 transcription factor expression and induction of TH2 cell differentiation. Immunity 30, 533-543 (2009
    • (2009) Immunity , vol.30 , pp. 533-543
    • Charles, N.1
  • 187
    • 84908256449 scopus 로고    scopus 로고
    • Immunoglobulin e plays an immunoregulatory role in lupus
    • Dema B., et al. Immunoglobulin E plays an immunoregulatory role in lupus. J. Exp. Med. 211, 2159-2168 (2014
    • (2014) J. Exp. Med , vol.211 , pp. 2159-2168
    • Dema, B.1
  • 188
    • 84886855686 scopus 로고    scopus 로고
    • Cgnz1 allele confers kidney resistance to damage preventing progression of immune complex-mediated acute lupus glomerulonephritis
    • Ge Y., et al. Cgnz1 allele confers kidney resistance to damage preventing progression of immune complex-mediated acute lupus glomerulonephritis. J. Exp. Med. 210, 2387-2401 (2013
    • (2013) J. Exp. Med , vol.210 , pp. 2387-2401
    • Ge, Y.1
  • 189
    • 84922496674 scopus 로고    scopus 로고
    • IRF5 deficiency ameliorates lupus but promotes atherosclerosis and metabolic dysfunction in a mouse model of lupus-associated atherosclerosis
    • Watkins A. A., et al. IRF5 deficiency ameliorates lupus but promotes atherosclerosis and metabolic dysfunction in a mouse model of lupus-associated atherosclerosis. J. Immunol. 194, 1467-1479 (2015
    • (2015) J. Immunol , vol.194 , pp. 1467-1479
    • Watkins, A.A.1
  • 190
    • 0032953105 scopus 로고    scopus 로고
    • Morbidity and mortality in systemic lupus erythematosus during a 5 year period A multicenter prospective study of 1,000 patients European working party on systemic lupus erythematosus
    • Cervera R., et al. Morbidity and mortality in systemic lupus erythematosus during a 5 year period. A multicenter prospective study of 1,000 patients. European Working Party on Systemic Lupus Erythematosus. Medicine (Baltimore) 78, 167-175 (1999
    • (1999) Medicine (Baltimore , vol.78 , pp. 167-175
    • Cervera, R.1
  • 191
    • 33750596706 scopus 로고    scopus 로고
    • Lupus nephritis in an Afro-Caribbean population: Renal indices and clinical outcomes
    • Flower C., Hennis A., Hambleton I. R., & Nicholson G. Lupus nephritis in an Afro-Caribbean population: renal indices and clinical outcomes. Lupus 15, 689-694 (2006
    • (2006) Lupus , vol.15 , pp. 689-694
    • Flower, C.1    Hennis, A.2    Hambleton, I.R.3    Nicholson, G.4
  • 192
    • 84923869887 scopus 로고    scopus 로고
    • Lupus nephritis susceptibility loci in women with systemic lupus erythematosus
    • Chung S. A., et al. Lupus nephritis susceptibility loci in women with systemic lupus erythematosus. J. Am. Soc. Nephrol. 25, 2859-2870 (2014
    • (2014) J. Am. Soc. Nephrol , vol.25 , pp. 2859-2870
    • Chung, S.A.1
  • 193
    • 0031040349 scopus 로고    scopus 로고
    • Gene expression of PDGF and PDGF receptor in various forms of glomerulonephritis
    • Matsuda M., et al. Gene expression of PDGF and PDGF receptor in various forms of glomerulonephritis. Am. J. Nephrol. 17, 25-31 (1997
    • (1997) Am. J. Nephrol , vol.17 , pp. 25-31
    • Matsuda, M.1
  • 194
    • 33645471300 scopus 로고    scopus 로고
    • Antagonism of PDGF D by human antibody CR002 prevents renal scarring in experimental glomerulonephritis
    • Ostendorf T., et al. Antagonism of PDGF D by human antibody CR002 prevents renal scarring in experimental glomerulonephritis. J. Am. Soc. Nephrol. 17, 1054-1062 (2006
    • (2006) J. Am. Soc. Nephrol , vol.17 , pp. 1054-1062
    • Ostendorf, T.1
  • 195
    • 84908131865 scopus 로고    scopus 로고
    • Decreased miR 26a expression correlates with the progression of podocyte injury in autoimmune glomerulonephritis
    • Ichii O., et al. Decreased miR 26a expression correlates with the progression of podocyte injury in autoimmune glomerulonephritis. PLoS ONE 9, e110383 2014
    • (2014) Plos One , vol.9 , pp. e110383
    • Ichii, O.1
  • 196
    • 73649090376 scopus 로고    scopus 로고
    • Viral RNA induces type i interferon-dependent cytokine release and cell death in mesangial cells via melanoma-differentiation-associated gene 5: Implications for viral infection-associated glomerulonephritis
    • Flur K., et al. Viral RNA induces type I interferon-dependent cytokine release and cell death in mesangial cells via melanoma-differentiation-associated gene 5: implications for viral infection-associated glomerulonephritis. Am. J. Pathol. 175, 2014-2022 (2009
    • (2009) Am. J. Pathol , vol.175 , pp. 2014-2022
    • Flur, K.1
  • 197
    • 82755186809 scopus 로고    scopus 로고
    • Cutting edge: Calcium/calmodulin-dependent protein kinase type IV is essential for mesangial cell proliferation and lupus nephritis
    • Ichinose K., et al. Cutting edge: calcium/calmodulin-dependent protein kinase type IV is essential for mesangial cell proliferation and lupus nephritis. J. Immunol. 187, 5500-5504 (2011
    • (2011) J. Immunol , vol.187 , pp. 5500-5504
    • Ichinose, K.1
  • 198
    • 84962092538 scopus 로고    scopus 로고
    • Lupus nephritis IgG induction of calcium/calmodulin-dependent kinase type IV expression in podocytes and alteration of their function
    • Ichinose K., et al. Lupus nephritis IgG induction of calcium/calmodulin-dependent kinase type IV expression in podocytes and alteration of their function. Arthritis Rheumatol. 68, 944-952 (2016
    • (2016) Arthritis Rheumatol , vol.68 , pp. 944-952
    • Ichinose, K.1
  • 199
    • 79551680278 scopus 로고    scopus 로고
    • Suppression of autoimmunity and organ pathology in lupus-prone mice upon inhibition of calcium/calmodulin-dependent protein kinase type IV
    • Ichinose K., Juang Y. T., Crispin J. C., Kis-Toth K., & Tsokos G. C. Suppression of autoimmunity and organ pathology in lupus-prone mice upon inhibition of calcium/calmodulin-dependent protein kinase type IV. Arthritis Rheum. 63, 523-529 (2011
    • (2011) Arthritis Rheum , vol.63 , pp. 523-529
    • Ichinose, K.1    Juang, Y.T.2    Crispin, J.C.3    Kis-Toth, K.4    Tsokos, G.C.5
  • 200
    • 84958603397 scopus 로고    scopus 로고
    • Glomerular cytokine expression in murine lupus nephritis
    • Tshilela K. A., et al. Glomerular cytokine expression in murine lupus nephritis. Clin. Exp. Nephrol. 20, 23-29 (2016
    • (2016) Clin. Exp. Nephrol , vol.20 , pp. 23-29
    • Tshilela, K.A.1
  • 201
    • 68149179247 scopus 로고    scopus 로고
    • Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL 23-TH17 pathway
    • Espinosa A., et al. Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL 23-TH17 pathway. J. Exp. Med. 206, 1661-1671 (2009
    • (2009) J. Exp. Med , vol.206 , pp. 1661-1671
    • Espinosa, A.1
  • 202
    • 67651097514 scopus 로고    scopus 로고
    • High Ro52 expression in spontaneous and UV induced cutaneous inflammation
    • Oke V., et al. High Ro52 expression in spontaneous and UV induced cutaneous inflammation. J. Invest. Dermatol. 129, 2000-2010 (2009
    • (2009) J. Invest. Dermatol , vol.129 , pp. 2000-2010
    • Oke, V.1
  • 203
    • 0242581986 scopus 로고    scopus 로고
    • Analysis of the molecular composition of Ro ribonucleoprotein complexes: Identification of novel y RNA-binding proteins
    • Fabini G., Rutjes S. A., Zimmermann C., Pruijn G. J., & Steiner G. Analysis of the molecular composition of Ro ribonucleoprotein complexes: identification of novel Y RNA-binding proteins. Eur. J. Biochem. 267, 2778-2789 (2000
    • (2000) Eur. J. Biochem , vol.267 , pp. 2778-2789
    • Fabini, G.1    Rutjes, S.A.2    Zimmermann, C.3    Pruijn, G.J.4    Steiner, G.5
  • 204
    • 84959860636 scopus 로고    scopus 로고
    • Genetic variants that are associated with neuropsychiatric systemic lupus erythematosus
    • Ho R. C., et al. Genetic variants that are associated with neuropsychiatric systemic lupus erythematosus. J. Rheumatol. 43, 541-551 (2016
    • (2016) J. Rheumatol , vol.43 , pp. 541-551
    • Ho, R.C.1
  • 205
    • 79958015275 scopus 로고    scopus 로고
    • Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort
    • Namjou B., et al. Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort. Genes Immun. 12, 270-279 (2011
    • (2011) Genes Immun , vol.12 , pp. 270-279
    • Namjou, B.1
  • 206
    • 77951224132 scopus 로고    scopus 로고
    • Inhibition of C5a receptor alleviates experimental CNS lupus
    • Jacob A., et al. Inhibition of C5a receptor alleviates experimental CNS lupus. J. Neuroimmunol. 221, 46-52 (2010
    • (2010) J. Neuroimmunol , vol.221 , pp. 46-52
    • Jacob, A.1
  • 207
    • 77953522365 scopus 로고    scopus 로고
    • C5a alters blood-brain barrier integrity in experimental lupus
    • Jacob A., et al. C5a alters blood-brain barrier integrity in experimental lupus. FASEB J. 24, 1682-1688 2010
    • (2010) FASEB J , vol.24 , pp. 1682-1688
    • Jacob, A.1
  • 208
    • 84954389233 scopus 로고    scopus 로고
    • A meta-analysis of serum and cerebrospinal fluid autoantibodies in neuropsychiatric systemic lupus erythematosus
    • Ho R. C., et al. A meta-analysis of serum and cerebrospinal fluid autoantibodies in neuropsychiatric systemic lupus erythematosus. Autoimmun. Rev. 15, 124-138 (2016
    • (2016) Autoimmun Rev , vol.15 , pp. 124-138
    • Ho, R.C.1
  • 209
    • 84878353733 scopus 로고    scopus 로고
    • Neuropsychiatric disease in murine lupus is dependent on the TWEAK/Fn14 pathway
    • Wen J., et al. Neuropsychiatric disease in murine lupus is dependent on the TWEAK/Fn14 pathway. J. Autoimmun. 43, 44-54 (2013
    • (2013) J. Autoimmun , vol.43 , pp. 44-54
    • Wen, J.1
  • 210
    • 0007274992 scopus 로고
    • Abnormal C1 in a patient with systemic lupus erythematosus
    • Pondman K. W., Stoop J. W., Cormane R. H., & Hannema A. J. Abnormal C1 in a patient with systemic lupus erythematosus. J. Immunol. 101, 811 (1968
    • (1968) J. Immunol , vol.101 , pp. 811
    • Pondman, K.W.1    Stoop, J.W.2    Cormane, R.H.3    Hannema, A.J.4
  • 211
    • 34948865177 scopus 로고    scopus 로고
    • Pediatric systemic lupus erythematosus with C1q deficiency
    • Kallel-Sellami M., et al. Pediatric systemic lupus erythematosus with C1q deficiency. Ann. NY Acad. Sci. 1108, 193-196 (2007
    • (2007) Ann. NY Acad. Sci , vol.1108 , pp. 193-196
    • Kallel-Sellami, M.1
  • 212
    • 80053627280 scopus 로고    scopus 로고
    • Clinical presentations and molecular basis of complement C1r deficiency in a male African-American patient with systemic lupus erythematosus
    • Wu Y. L., Brookshire B. P., Verani R. R., Arnett F. C., & Yu C. Y. Clinical presentations and molecular basis of complement C1r deficiency in a male African-American patient with systemic lupus erythematosus. Lupus 20, 1126-1134 (2011
    • (2011) Lupus , vol.20 , pp. 1126-1134
    • Wu, Y.L.1    Brookshire, B.P.2    Verani, R.R.3    Arnett, F.C.4    Yu, C.Y.5
  • 213
    • 0026629692 scopus 로고
    • Selective deficiency of C1s associated with a systemic lupus erythematosus-like syndrome report of a case
    • Suzuki Y., Ogura Y., Otsubo O., Akagi K., & Fujita T. Selective deficiency of C1s associated with a systemic lupus erythematosus-like syndrome. Report of a case. Arthritis Rheum. 35, 576-579 (1992
    • (1992) Arthritis Rheum , vol.35 , pp. 576-579
    • Suzuki, Y.1    Ogura, Y.2    Otsubo, O.3    Akagi, K.4    Fujita, T.5
  • 215
    • 0018463971 scopus 로고
    • C2 deficiency and a lupus erythematosus-like illness: Family re evaluation
    • Wahl R., et al. C2 deficiency and a lupus erythematosus-like illness: family re evaluation. Ann. Intern. Med. 90, 717-718 (1979
    • (1979) Ann Intern. Med , vol.90 , pp. 717-718
    • Wahl, R.1
  • 216
    • 0018834558 scopus 로고
    • Complement deficiency and nephritis: A report of a family
    • Pussell B. A., Bourke E., Nayef M., Morris S., & Peters D. K. Complement deficiency and nephritis: a report of a family. Lancet 1, 675-677 (1980
    • (1980) Lancet , vol.1 , pp. 675-677
    • Pussell, B.A.1    Bourke, E.2    Nayef, M.3    Morris, S.4    Peters, D.K.5
  • 217
    • 84889009074 scopus 로고    scopus 로고
    • Clinical manifestations of disease in X linked carriers of chronic granulomatous disease
    • Battersby A. C., Cale A. M., Goldblatt D., & Gennery A. R. Clinical manifestations of disease in X linked carriers of chronic granulomatous disease. J. Clin. Immunol. 33, 1276-1284 (2013
    • (2013) J. Clin. Immunol , vol.33 , pp. 1276-1284
    • Battersby, A.C.1    Cale, A.M.2    Goldblatt, D.3    Gennery, A.R.4
  • 218
    • 77952095497 scopus 로고    scopus 로고
    • Prolidase deficiency: It looks like systemic lupus erythematosus but it is not
    • Klar A., et al. Prolidase deficiency: it looks like systemic lupus erythematosus but it is not. Eur. J. Pediatr. 169, 727-732 (2010
    • (2010) Eur. J. Pediatr , vol.169 , pp. 727-732
    • Klar, A.1
  • 219
    • 2442675182 scopus 로고    scopus 로고
    • Sisters with α mannosidosis and systemic lupus erythematosus
    • Urushihara M., et al. Sisters with α mannosidosis and systemic lupus erythematosus. Eur. J. Pediatr. 163, 192-195 (2004
    • (2004) Eur. J. Pediatr , vol.163 , pp. 192-195
    • Urushihara, M.1
  • 220
    • 33749006867 scopus 로고    scopus 로고
    • Familial chilblain lupus a monogenic form of cutaneous lupus erythematosus maps to chromosome 3p
    • Lee-Kirsch M. A., et al. Familial chilblain lupus a monogenic form of cutaneous lupus erythematosus maps to chromosome 3p. Am. J. Hum. Genet. 79, 731-737 (2006
    • (2006) Am. J. Hum. Genet , vol.79 , pp. 731-737
    • Lee-Kirsch, M.A.1
  • 221
    • 34147185679 scopus 로고    scopus 로고
    • Heterozygous mutations in TREX1 cause familial chilblain lupus and dominant Aicardi- Goutières syndrome
    • Rice G., et al. Heterozygous mutations in TREX1 cause familial chilblain lupus and dominant Aicardi- Goutières syndrome. Am. J. Hum. Genet. 80, 811-815 (2007
    • (2007) Am. J. Hum. Genet , vol.80 , pp. 811-815
    • Rice, G.1
  • 222
    • 0034939627 scopus 로고    scopus 로고
    • Mutation of DNASE1 in people with systemic lupus erythematosus
    • Yasutomo K., et al. Mutation of DNASE1 in people with systemic lupus erythematosus. Nat. Genet. 28, 313-314 (2001
    • (2001) Nat. Genet , vol.28 , pp. 313-314
    • Yasutomo, K.1
  • 223
    • 80455129268 scopus 로고    scopus 로고
    • Aicardi-Goutières syndrome and systemic lupus erythematosus (SLE) in a 12 year-old boy with SAMHD1 mutations
    • Ramantani G., et al. Aicardi-Goutières syndrome and systemic lupus erythematosus (SLE) in a 12 year-old boy with SAMHD1 mutations. J. Child Neurol. 26, 1425-1428 (2011
    • (2011) J. Child Neurol , vol.26 , pp. 1425-1428
    • Ramantani, G.1
  • 224
    • 79251551861 scopus 로고    scopus 로고
    • Tartrate-resistant acid phosphatase deficiency causes a bone dysplasia with autoimmunity and a type i interferon expression signature
    • Briggs T. A., et al. Tartrate-resistant acid phosphatase deficiency causes a bone dysplasia with autoimmunity and a type I interferon expression signature. Nat. Genet. 43, 127-131 (2011
    • (2011) Nat. Genet , vol.43 , pp. 127-131
    • Briggs, T.A.1
  • 225
    • 84921417123 scopus 로고    scopus 로고
    • Characterization of human disease phenotypes associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR and IFIH1
    • Crow Y. J., et al. Characterization of human disease phenotypes associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR and IFIH1. Am. J. Med. Genet. A 167A, 296-312 (2015
    • (2015) Am. J. Med. Genet. A , vol.167 A , pp. 296-312
    • Crow, Y.J.1
  • 226
    • 84868207785 scopus 로고    scopus 로고
    • Mutations in ADAR1 cause Aicardi- Goutières syndrome associated with a type i interferon signature
    • Rice G. I., et al. Mutations in ADAR1 cause Aicardi- Goutières syndrome associated with a type I interferon signature. Nat. Genet. 44, 1243-1248 (2012
    • (2012) Nat. Genet , vol.44 , pp. 1243-1248
    • Rice, G.I.1
  • 227
    • 84925137606 scopus 로고    scopus 로고
    • Mutations in DDX58, which encodes RIG I, cause atypical singleton-merten syndrome
    • Jang M. A., et al. Mutations in DDX58, which encodes RIG I, cause atypical Singleton-Merten syndrome. Am. J. Hum. Genet. 96, 266-274 (2015
    • (2015) Am. J. Hum. Genet , vol.96 , pp. 266-274
    • Jang, M.A.1
  • 228
    • 84905825645 scopus 로고    scopus 로고
    • Activated STING in a vascular and pulmonary syndrome
    • Liu Y., et al. Activated STING in a vascular and pulmonary syndrome. N. Engl. J. Med. 371, 507-518 (2014
    • (2014) N. Engl. J. Med , vol.371 , pp. 507-518
    • Liu, Y.1
  • 229
    • 84922880395 scopus 로고    scopus 로고
    • Human intracelluqlar SG15 prevents interferon α/β over-amplification and auto-inflammation
    • Zhang X., et al. Human intracellular ISG15 prevents interferon α/β over-amplification and auto-inflammation. Nature 517, 89-93 (2015
    • (2015) Nature , vol.517 , pp. 89-93
    • Zhang, X.1
  • 230
    • 84946780874 scopus 로고    scopus 로고
    • Additive loss of function proteasome subunit mutations in CANDLE/PRAAS patients promote type i IFN production
    • Brehm A., et al. Additive loss of function proteasome subunit mutations in CANDLE/PRAAS patients promote type I IFN production. J. Clin. Invest. 125, 4196-4211 (2015
    • (2015) J. Clin. Invest , vol.125 , pp. 4196-4211
    • Brehm, A.1
  • 231
    • 0029737324 scopus 로고    scopus 로고
    • Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease
    • Wu J., et al. Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease. J. Clin. Invest. 98, 1107-1113 (1996
    • (1996) J. Clin. Invest , vol.98 , pp. 1107-1113
    • Wu, J.1
  • 232
    • 84871302106 scopus 로고    scopus 로고
    • Association of FAS gene polymorphisms with systemic lupus erythematosus: A meta-analysis
    • Xiang N., Li X. M., Wang G. S., Tao J. H., & Li X. P. Association of FAS gene polymorphisms with systemic lupus erythematosus: a meta-analysis. Mol. Biol. Rep. 40, 407-415 (2013
    • (2013) Mol. Biol. Rep , vol.40 , pp. 407-415
    • Xiang, N.1    Li, X.M.2    Wang, G.S.3    Tao, J.H.4    Li, X.P.5
  • 233
    • 0029006893 scopus 로고
    • Mutations in FAS associated with human lymphoproliferative syndrome and autoimmunity
    • Rieux-Laucat F., et al. Mutations in FAS associated with human lymphoproliferative syndrome and autoimmunity. Science 268, 1347-1349 (1995
    • (1995) Science , vol.268 , pp. 1347-1349
    • Rieux-Laucat, F.1
  • 234
    • 84886085781 scopus 로고    scopus 로고
    • Are RASopathies new monogenic predisposing conditions to the development of systemic lupus erythematosus? Case report and systematic review of the literature
    • Bader-Meunier B., et al. Are RASopathies new monogenic predisposing conditions to the development of systemic lupus erythematosus? Case report and systematic review of the literature. Semin. Arthritis Rheum. 43, 217-219 (2013
    • (2013) Semin. Arthritis Rheum , vol.43 , pp. 217-219
    • Bader-Meunier, B.1
  • 235
    • 84896710741 scopus 로고    scopus 로고
    • Autoimmunity due to RAG deficiency and estimated disease incidence in RAG1/2 mutations
    • e810
    • Chen K., et al. Autoimmunity due to RAG deficiency and estimated disease incidence in RAG1/2 mutations. J. Allergy Clin. Immunol. 133, 880-882. e810 (2014
    • (2014) J. Allergy Clin. Immunol , vol.133 , pp. 880-882
    • Chen, K.1
  • 236
    • 84920461307 scopus 로고    scopus 로고
    • Impaired receptor editing and heterozygous RAG2 mutation in a patient with systemic lupus erythematosus and erosive arthritis
    • Walter J. E., et al. Impaired receptor editing and heterozygous RAG2 mutation in a patient with systemic lupus erythematosus and erosive arthritis. J. Allergy Clin. Immunol. 135, 272-273 (2014
    • (2014) J. Allergy Clin. Immunol , vol.135 , pp. 272-273
    • Walter, J.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.