Increased expression of TLR2 in CD4+ T cells from SLE patients enhances immune reactivity and promotes IL-17 expression through histone modifications

European Journal of Immunology

Volumn 45, Issue 9, 2015, Pages 2683-2693

  Liu, Yu ^a   Liao, Jieyue ^a   Zhao, Ming ^a   Wu, Haijing ^a   Yung, Susan ^b   Chan, Tak Mao ^b   Yoshimura, Akihiko ^c   Lu, Qianjin ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Histone modification; IL 17; Systemic lupus erythematosus; T cells; TLR2

Indexed keywords

BETA ACTIN; CD19 ANTIGEN; CD40 LIGAND; CD70 ANTIGEN; HISTONE H3; HYDROXYCHLOROQUINE; INTERLEUKIN 17; INTERLEUKIN 17F; METHYLPREDNISOLONE; PREDNISONE; THALIDOMIDE; TOLL LIKE RECEPTOR 2; TRIAMCINOLONE; CD70 PROTEIN, HUMAN; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, HUMAN; HISTONE; IL17A PROTEIN, HUMAN; IL17F PROTEIN, HUMAN; SMALL INTERFERING RNA; TLR2 PROTEIN, HUMAN;

ACETYLATION; ADOLESCENT; ADULT; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HISTONE MODIFICATION; HUMAN; IMMUNOREACTIVITY; INFLAMMATION; MALE; METHYLATION; MONOCYTE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SYSTEMIC LUPUS ERYTHEMATOSUS; ANTAGONISTS AND INHIBITORS; DNA METHYLATION; GENETIC EPIGENESIS; GENETICS; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; MIDDLE AGED; PATHOLOGY; PRIMARY CELL CULTURE; SIGNAL TRANSDUCTION;

ADOLESCENT; ADULT; ANTIGENS, CD70; B-LYMPHOCYTES; CD4-POSITIVE T-LYMPHOCYTES; CD40 LIGAND; CD8-POSITIVE T-LYMPHOCYTES; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; HISTONES; HUMANS; IMMUNITY, INNATE; INTERLEUKIN-17; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MIDDLE AGED; PRIMARY CELL CULTURE; PROMOTER REGIONS, GENETIC; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2;

EID: 84940960375     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201445219     Document Type: Article

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