BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones

Nature Structural and Molecular Biology

Volumn 21, Issue 12, 2014, Pages 1047-1057

  Kanno, Tomohiko ^a,b   Kanno, Yuka ^c   Leroy, Gary ^d   Campos, Eric ^d   Sun, Hong Wei ^c   Brooks, Stephen R ^c   Vahedi, Golnaz ^c   Heightman, Tom D ^e,g   Garcia, Benjamin A ^f   Reinberg, Danny ^d   Siebenlist, Ulrich ^a   O'Shea, John J ^c   Ozato, Keiko ^b  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^d NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f UNIVERSITY OF PENNSYLVANIA   (United States)

^g ASTEX PHARMACEUTICALS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN BRD4; PROTEIN DERIVATIVE; RNA POLYMERASE II; UNCLASSIFIED DRUG; UNTRANSLATED RNA; BRD4 PROTEIN, MOUSE; HISTONE; NUCLEAR PROTEIN; NUCLEOSOME; POSITIVE TRANSCRIPTION ELONGATION FACTOR B; RNA; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME RELEASE; HISTONE ACETYLATION; INTERACTIONS WITH RNA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RNA ANALYSIS; RNA TRANSCRIPTION; RNA TRANSLATION; 3T3 CELL LINE; ACETYLATION; ANIMAL; ANTAGONISTS AND INHIBITORS; ENHANCER REGION; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; NUCLEOSOME; TRANSCRIPTION ELONGATION; TRANSCRIPTION INITIATION;

ACETYLATION; ANIMALS; ENHANCER ELEMENTS, GENETIC; HEK293 CELLS; HISTONES; HUMANS; MICE; NIH 3T3 CELLS; NUCLEAR PROTEINS; NUCLEOSOMES; POSITIVE TRANSCRIPTIONAL ELONGATION FACTOR B; PROTEIN INTERACTION MAPS; RNA; RNA POLYMERASE II; RNA, UNTRANSLATED; TRANSCRIPTION ELONGATION, GENETIC; TRANSCRIPTION FACTORS; TRANSCRIPTION INITIATION, GENETIC;

EID: 84925556593     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.2912     Document Type: Article

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