Inhibition of C5a receptor alleviates experimental CNS lupus

Journal of Neuroimmunology

Volumn 221, Issue 1-2, 2010, Pages 46-52

  Jacob, Alexander ^a   Hack, Bradley ^a   Bai, Tao ^a   Brorson, James R ^a   Quigg, Richard J ^a   Alexander, Jessy J ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

Anaphylatoxins; Brain; Complement system; Inflammation; Systemic lupus erythematosus

Indexed keywords

COMPLEMENT COMPONENT C5A RECEPTOR; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; STAT1 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; C5ARAD; CELL ADHESION MOLECULE; COMPLEMENT COMPONENT C5A; CXCL2 CHEMOKINE; INTERCELLULAR ADHESION MOLECULE 1; LIPOCORTIN 5;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN; BRAIN VASCULITIS; CELL LOSS; CENTRAL NERVOUS SYSTEM DISEASE; COMPLEMENT ACTIVATION; CONTROLLED STUDY; GENE EXPRESSION; MOUSE; MURPHY ROTHS LARGE LYMPHOPROLIFERATIVE MOUSE; NERVE CELL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SERUM; SIGNAL TRANSDUCTION; SYSTEMIC LUPUS ERYTHEMATOSUS; ANIMAL; ANIMAL EMBRYO; CELL CULTURE; CYTOLOGY; DISEASE MODEL; DRUG EFFECT; GENETICS; MALE; METABOLISM; METHODOLOGY; NICK END LABELING; PATHOLOGY; UPREGULATION;

ANIMALS; ANNEXIN A5; APOPTOSIS; BRAIN; CELL ADHESION MOLECULES; CELLS, CULTURED; CHEMOKINE CXCL2; COMPLEMENT C5A; DISEASE MODELS, ANIMAL; EMBRYO, MAMMALIAN; IN SITU NICK-END LABELING; INTERCELLULAR ADHESION MOLECULE-1; LUPUS VASCULITIS, CENTRAL NERVOUS SYSTEM; MALE; MICE; MICE, INBRED MRL LPR; NEURONS; NITRIC OXIDE SYNTHASE TYPE II; RECEPTOR, ANAPHYLATOXIN C5A; RNA, MESSENGER; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 77951224132     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2010.02.011     Document Type: Article

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