Renal involvement in lupus is characterized by unique DNA methylation changes in naïve CD4+ T cells

Journal of Autoimmunity

Volumn 61, Issue , 2015, Pages 29-35

  Coit, Patrick ^a   Renauer, Paul ^a   Jeffries, Matlock A ^b   Merrill, Joan T ^c   McCune, W Joseph ^a   Maksimowicz McKinnon, Kathleen ^d   Sawalha, Amr H ^a,e  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^c OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^d HENRY FORD HEALTH SYSTEM   (United States)

^e UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Biomarker; Epigenetics; EWAS; Lupus; Methylation; Nephritis

Indexed keywords

CD4 ANTIGEN; MITOGEN ACTIVATED PROTEIN KINASE; UPSTREAM STIMULATORY FACTOR; DUAL SPECIFICITY PHOSPHATASE; DUSP5 PROTEIN, HUMAN; INTERFERON REGULATORY FACTOR 7; PROTEIN TYROSINE KINASE; TNK2 PROTEIN, HUMAN;

ADULT; ARTICLE; CD4+ T LYMPHOCYTE; CD80 GENE; CHST12 GENE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; DUSP5 GENE; EPIGENETICS; FEMALE; GENE; GENE LOCUS; GENETIC SUSCEPTIBILITY; HERC5 GENE; HUMAN; HUMAN CELL; IFI44 GENE; IRF7 GENE; ISG15 GENE; ISG20 GENE; ITGAX GENE; LUPUS ERYTHEMATOSUS NEPHRITIS; MAJOR CLINICAL STUDY; PARP12 GENE; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION; SYSTEMIC LUPUS ERYTHEMATOSUS; TNK2 GENE; CASE CONTROL STUDY; GENETICS; GENOME-WIDE ASSOCIATION STUDY; KIDNEY; METABOLISM; MIDDLE AGED; PATHOLOGY; PROCEDURES;

ADULT; CASE-CONTROL STUDIES; CD4-POSITIVE T-LYMPHOCYTES; DNA METHYLATION; DUAL-SPECIFICITY PHOSPHATASES; FEMALE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; INTERFERON REGULATORY FACTOR-7; KIDNEY; LUPUS ERYTHEMATOSUS, SYSTEMIC; LUPUS NEPHRITIS; MIDDLE AGED; PROTEIN-TYROSINE KINASES;

EID: 84937516401     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2015.05.003     Document Type: Article

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