-
1
-
-
84871509601
-
The resolution of inflammation
-
1 Buckley, C.D., et al. The resolution of inflammation. Nat. Rev. Immunol. 13 (2013), 59–66.
-
(2013)
Nat. Rev. Immunol.
, vol.13
, pp. 59-66
-
-
Buckley, C.D.1
-
2
-
-
77953483260
-
Age-related neuroinflammatory changes negatively impact on neuronal function
-
2 Lynch, M.A., Age-related neuroinflammatory changes negatively impact on neuronal function. Front. Aging Neurosci., 1, 2010, 6.
-
(2010)
Front. Aging Neurosci.
, vol.1
, pp. 6
-
-
Lynch, M.A.1
-
3
-
-
84929921146
-
Immune attack: the role of inflammation in Alzheimer disease
-
3 Heppner, F.L., et al. Immune attack: the role of inflammation in Alzheimer disease. Nat. Rev. Neurosci. 16 (2015), 358–372.
-
(2015)
Nat. Rev. Neurosci.
, vol.16
, pp. 358-372
-
-
Heppner, F.L.1
-
4
-
-
33847613885
-
Inflammatory processes in Alzheimer's disease
-
4 Heneka, M.T., O'Banion, M.K., Inflammatory processes in Alzheimer's disease. J. Neuroimmunol. 184 (2007), 69–91.
-
(2007)
J. Neuroimmunol.
, vol.184
, pp. 69-91
-
-
Heneka, M.T.1
O'Banion, M.K.2
-
5
-
-
72449204160
-
Does neuroinflammation fan the flame in neurodegenerative diseases?
-
5 Frank-Cannon, T.C., et al. Does neuroinflammation fan the flame in neurodegenerative diseases?. Mol. Neurodegen. 4 (2009), 1–13.
-
(2009)
Mol. Neurodegen.
, vol.4
, pp. 1-13
-
-
Frank-Cannon, T.C.1
-
6
-
-
84940453103
-
Immunopathology of multiple sclerosis
-
6 Dendrou, C.A., et al. Immunopathology of multiple sclerosis. Nat. Rev. Immunol. 15 (2015), 545–558.
-
(2015)
Nat. Rev. Immunol.
, vol.15
, pp. 545-558
-
-
Dendrou, C.A.1
-
7
-
-
77954865635
-
Systemic inflammatory cells fight off neurodegenerative disease
-
7 Schwartz, M., Shechter, R., Systemic inflammatory cells fight off neurodegenerative disease. Nat. Rev. Neurol. 6 (2010), 405–410.
-
(2010)
Nat. Rev. Neurol.
, vol.6
, pp. 405-410
-
-
Schwartz, M.1
Shechter, R.2
-
8
-
-
0031849511
-
Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats
-
8 Rapalino, O., et al. Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats. Nat. Med. 4 (1998), 814–821.
-
(1998)
Nat. Med.
, vol.4
, pp. 814-821
-
-
Rapalino, O.1
-
9
-
-
0033049143
-
Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy
-
9 Moalem, G., et al. Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy. Nat. Med. 5 (1999), 49–55.
-
(1999)
Nat. Med.
, vol.5
, pp. 49-55
-
-
Moalem, G.1
-
10
-
-
0035370214
-
Protective autoimmunity is a physiological response to CNS trauma
-
10 Yoles, E., et al. Protective autoimmunity is a physiological response to CNS trauma. J. Neurosci. 21 (2001), 3740–3748.
-
(2001)
J. Neurosci.
, vol.21
, pp. 3740-3748
-
-
Yoles, E.1
-
11
-
-
33845628839
-
What is immune privilege (not)?
-
11 Galea, I., et al. What is immune privilege (not)?. Trends Immunol. 28 (2007), 12–18.
-
(2007)
Trends Immunol.
, vol.28
, pp. 12-18
-
-
Galea, I.1
-
12
-
-
84942518278
-
Revisiting the mechanisms of CNS immune privilege
-
12 Louveau, A., et al. Revisiting the mechanisms of CNS immune privilege. Trends Immunol. 36 (2015), 569–577.
-
(2015)
Trends Immunol.
, vol.36
, pp. 569-577
-
-
Louveau, A.1
-
13
-
-
77950013567
-
Protective autoimmunity functions by intracranial immunosurveillance to support the mind: the missing link between health and disease
-
13 Schwartz, M., Shechter, R., Protective autoimmunity functions by intracranial immunosurveillance to support the mind: the missing link between health and disease. Mol. Psychiatry 15 (2010), 342–354.
-
(2010)
Mol. Psychiatry
, vol.15
, pp. 342-354
-
-
Schwartz, M.1
Shechter, R.2
-
14
-
-
84866391516
-
Pro-cognitive properties of T cells
-
14 Kipnis, J., et al. Pro-cognitive properties of T cells. Nat. Rev. Immunol. 12 (2012), 663–669.
-
(2012)
Nat. Rev. Immunol.
, vol.12
, pp. 663-669
-
-
Kipnis, J.1
-
15
-
-
84894646177
-
The resolution of neuroinflammation in neurodegeneration: leukocyte recruitment via the choroid plexus
-
15 Schwartz, M., Baruch, K., The resolution of neuroinflammation in neurodegeneration: leukocyte recruitment via the choroid plexus. EMBO J. 33 (2014), 7–22.
-
(2014)
EMBO J.
, vol.33
, pp. 7-22
-
-
Schwartz, M.1
Baruch, K.2
-
16
-
-
77956536780
-
T cells in multiple sclerosis and experimental autoimmune encephalomyelitis
-
16 Fletcher, J.M., et al. T cells in multiple sclerosis and experimental autoimmune encephalomyelitis. Clin. Exp. Immunol. 162 (2010), 1–11.
-
(2010)
Clin. Exp. Immunol.
, vol.162
, pp. 1-11
-
-
Fletcher, J.M.1
-
17
-
-
1842732224
-
Loss of functional suppression by CD4+ CD25+ regulatory T cells in patients with multiple sclerosis
-
17 Viglietta, V., et al. Loss of functional suppression by CD4+ CD25+ regulatory T cells in patients with multiple sclerosis. J. Exp. Med. 199 (2004), 971–979.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 971-979
-
-
Viglietta, V.1
-
18
-
-
84862746826
-
Immune checkpoints in central nervous system autoimmunity
-
18 Joller, N., et al. Immune checkpoints in central nervous system autoimmunity. Immunol. Rev. 248 (2012), 122–139.
-
(2012)
Immunol. Rev.
, vol.248
, pp. 122-139
-
-
Joller, N.1
-
19
-
-
84899418705
-
Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease
-
19 Prinz, M., Priller, J., Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease. Nat. Rev. Neurosci. 15 (2014), 300–312.
-
(2014)
Nat. Rev. Neurosci.
, vol.15
, pp. 300-312
-
-
Prinz, M.1
Priller, J.2
-
20
-
-
84874506801
-
Contribution of vitamin D insufficiency to the pathogenesis of multiple sclerosis
-
20 Pierrot-Deseilligny, C., Souberbielle, J.C., Contribution of vitamin D insufficiency to the pathogenesis of multiple sclerosis. Ther. Adv. Neurol. Disord. 6 (2013), 81–116.
-
(2013)
Ther. Adv. Neurol. Disord.
, vol.6
, pp. 81-116
-
-
Pierrot-Deseilligny, C.1
Souberbielle, J.C.2
-
21
-
-
85014215234
-
Crosstalk between vitamin B and immunity
-
21 Spinas, E., et al. Crosstalk between vitamin B and immunity. J. Biol. Regul. Homeost. Agents 29 (2015), 283–288.
-
(2015)
J. Biol. Regul. Homeost. Agents
, vol.29
, pp. 283-288
-
-
Spinas, E.1
-
22
-
-
58849143335
-
Accumulated amyloid-β peptide and hyperphosphorylated tau protein: relationship and links in Alzheimer's disease
-
22 Huang, H-C., Jiang, Z-F., Accumulated amyloid-β peptide and hyperphosphorylated tau protein: relationship and links in Alzheimer's disease. J. Alzheimers Dis. 16 (2009), 15–27.
-
(2009)
J. Alzheimers Dis.
, vol.16
, pp. 15-27
-
-
Huang, H.-C.1
Jiang, Z.-F.2
-
23
-
-
84939000054
-
Neutrophils promote Alzheimer's disease-like pathology and cognitive decline via LFA-1 integrin
-
23 Zenaro, E., et al. Neutrophils promote Alzheimer's disease-like pathology and cognitive decline via LFA-1 integrin. Nat. Med. 21 (2015), 880–886.
-
(2015)
Nat. Med.
, vol.21
, pp. 880-886
-
-
Zenaro, E.1
-
24
-
-
84924673435
-
Migration of blood cells to β-amyloid plaques in Alzheimer's disease
-
24 Hohsfield, L.A., Humpel, C., Migration of blood cells to β-amyloid plaques in Alzheimer's disease. Exp. Gerontol. 65 (2015), 8–15.
-
(2015)
Exp. Gerontol.
, vol.65
, pp. 8-15
-
-
Hohsfield, L.A.1
Humpel, C.2
-
25
-
-
84939490054
-
Breaking immune tolerance by targeting Foxp3(+) regulatory T cells mitigates Alzheimer's disease pathology
-
25 Baruch, K., et al. Breaking immune tolerance by targeting Foxp3(+) regulatory T cells mitigates Alzheimer's disease pathology. Nat. Commun., 6, 2015, 7967.
-
(2015)
Nat. Commun.
, vol.6
, pp. 7967
-
-
Baruch, K.1
-
26
-
-
84957431867
-
PD-1 immune checkpoint blockade reduces pathology and improves memory in mouse models of Alzheimer's disease
-
26 Baruch, K., et al. PD-1 immune checkpoint blockade reduces pathology and improves memory in mouse models of Alzheimer's disease. Nat. Med. 22 (2016), 135–137.
-
(2016)
Nat. Med.
, vol.22
, pp. 135-137
-
-
Baruch, K.1
-
27
-
-
78149360132
-
Fate mapping analysis reveals that adult microglia derive from primitive macrophages
-
27 Ginhoux, F., et al. Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science 330 (2010), 841–845.
-
(2010)
Science
, vol.330
, pp. 841-845
-
-
Ginhoux, F.1
-
28
-
-
84976883162
-
Microglia development follows a stepwise program to regulate brain homeostasis
-
28 Matcovitch-Natan, O., et al. Microglia development follows a stepwise program to regulate brain homeostasis. Science, 2016, 23.
-
(2016)
Science
, pp. 23
-
-
Matcovitch-Natan, O.1
-
29
-
-
84960388165
-
Microglial physiology and pathophysiology: insights from genome-wide transcriptional profiling
-
29 Crotti, A., Ransohoff, R.M., Microglial physiology and pathophysiology: insights from genome-wide transcriptional profiling. Immunity 44 (2016), 505–515.
-
(2016)
Immunity
, vol.44
, pp. 505-515
-
-
Crotti, A.1
Ransohoff, R.M.2
-
30
-
-
84893745524
-
Identification of a unique TGF-[beta]-dependent molecular and functional signature in microglia
-
30 Butovsky, O., et al. Identification of a unique TGF-[beta]-dependent molecular and functional signature in microglia. Nat. Neurosci. 17 (2014), 131–143.
-
(2014)
Nat. Neurosci.
, vol.17
, pp. 131-143
-
-
Butovsky, O.1
-
31
-
-
84955557892
-
Safflower yellow regulates microglial polarization and inhibits inflammatory response in LPS-stimulated Bv2 cells
-
31 Yang, X.W., et al. Safflower yellow regulates microglial polarization and inhibits inflammatory response in LPS-stimulated Bv2 cells. Int. J. Immunopathol. Pharmacol. 29 (2016), 54–64.
-
(2016)
Int. J. Immunopathol. Pharmacol.
, vol.29
, pp. 54-64
-
-
Yang, X.W.1
-
32
-
-
84994809320
-
Role of TNF in mast cell neuroinflammation and pain.
-
BIOLIFE SAS VIA S STEFANO 39 BIS, 64029 SILVA MARINA (TE) ITALY
-
32 Gu, Y., et al. Role of TNF in mast cell neuroinflammation and pain. 2015, BIOLIFE SAS VIA S STEFANO 39 BIS, 64029 SILVA MARINA (TE), ITALY.
-
(2015)
-
-
Gu, Y.1
-
33
-
-
77951879282
-
Infiltration of Th1 and Th17 cells and activation of microglia in the CNS during the course of experimental autoimmune encephalomyelitis
-
33 Murphy, Á.C., et al. Infiltration of Th1 and Th17 cells and activation of microglia in the CNS during the course of experimental autoimmune encephalomyelitis. Brain Behav. Immun. 24 (2010), 641–651.
-
(2010)
Brain Behav. Immun.
, vol.24
, pp. 641-651
-
-
Murphy, Á.C.1
-
34
-
-
84902537095
-
Phagocytosis of microglia in the central nervous system diseases
-
34 Fu, R., et al. Phagocytosis of microglia in the central nervous system diseases. Mol. Neurobiol. 49 (2014), 1422–1434.
-
(2014)
Mol. Neurobiol.
, vol.49
, pp. 1422-1434
-
-
Fu, R.1
-
35
-
-
84923253406
-
Microglia in action: how aging and injury can change the brain's guardians
-
35 Lourbopoulos, A., et al. Microglia in action: how aging and injury can change the brain's guardians. Front. Cell. Neurosci., 9, 2015, 54.
-
(2015)
Front. Cell. Neurosci.
, vol.9
, pp. 54
-
-
Lourbopoulos, A.1
-
36
-
-
84886953273
-
A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation
-
36 Goldmann, T., et al. A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation. Nat. Neurosci. 16 (2013), 1618–1626.
-
(2013)
Nat. Neurosci.
, vol.16
, pp. 1618-1626
-
-
Goldmann, T.1
-
37
-
-
84905116959
-
Differential roles of microglia and monocytes in the inflamed central nervous system
-
37 Yamasaki, R., et al. Differential roles of microglia and monocytes in the inflamed central nervous system. J. Exp. Med. 211 (2014), 1533–1549.
-
(2014)
J. Exp. Med.
, vol.211
, pp. 1533-1549
-
-
Yamasaki, R.1
-
38
-
-
43049177588
-
Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system
-
38 Prinz, M., et al. Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system. Immunity 28 (2008), 675–686.
-
(2008)
Immunity
, vol.28
, pp. 675-686
-
-
Prinz, M.1
-
39
-
-
68049143269
-
Infiltrating blood-derived macrophages are vital cells playing an anti-inflammatory role in recovery from spinal cord injury in mice
-
39 Shechter, R., et al. Infiltrating blood-derived macrophages are vital cells playing an anti-inflammatory role in recovery from spinal cord injury in mice. PLoS Med., 6, 2009, e1000113.
-
(2009)
PLoS Med.
, vol.6
, pp. e1000113
-
-
Shechter, R.1
-
40
-
-
84858259145
-
Clearance of amyloid-β peptides by microglia and macrophages: the issue of what, when and where
-
40 Lai, A.Y., McLaurin, J., Clearance of amyloid-β peptides by microglia and macrophages: the issue of what, when and where. Future Neurol. 7 (2012), 165–176.
-
(2012)
Future Neurol.
, vol.7
, pp. 165-176
-
-
Lai, A.Y.1
McLaurin, J.2
-
41
-
-
84906313533
-
In acute experimental autoimmune encephalomyelitis, infiltrating macrophages are immune activated, whereas microglia remain immune suppressed
-
41 Vainchtein, I.D., et al. In acute experimental autoimmune encephalomyelitis, infiltrating macrophages are immune activated, whereas microglia remain immune suppressed. Glia 62 (2014), 1724–1735.
-
(2014)
Glia
, vol.62
, pp. 1724-1735
-
-
Vainchtein, I.D.1
-
42
-
-
84946564936
-
Stage-specific role of interferon-gamma in experimental autoimmune encephalomyelitis and multiple sclerosis
-
42 Arellano, G., et al. Stage-specific role of interferon-gamma in experimental autoimmune encephalomyelitis and multiple sclerosis. Front. Immunol., 6, 2015, 492.
-
(2015)
Front. Immunol.
, vol.6
, pp. 492
-
-
Arellano, G.1
-
43
-
-
84918825145
-
Chronic exposure to TGFβ1 regulates myeloid cell inflammatory response in an IRF7 - dependent manner
-
43 Cohen, M., et al. Chronic exposure to TGFβ1 regulates myeloid cell inflammatory response in an IRF7 - dependent manner. EMBO J. 33 (2014), 2906–2921.
-
(2014)
EMBO J.
, vol.33
, pp. 2906-2921
-
-
Cohen, M.1
-
44
-
-
84924737031
-
TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models
-
44 Jay, T.R., et al. TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models. J. Exp. Med. 212 (2015), 287–295.
-
(2015)
J. Exp. Med.
, vol.212
, pp. 287-295
-
-
Jay, T.R.1
-
45
-
-
84925464993
-
TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model
-
45 Wang, Y., et al. TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model. Cell 160 (2015), 1061–1071.
-
(2015)
Cell
, vol.160
, pp. 1061-1071
-
-
Wang, Y.1
-
46
-
-
84959118543
-
TREM2 variants: new keys to decipher Alzheimer disease pathogenesis
-
46 Colonna, M., Wang, Y., TREM2 variants: new keys to decipher Alzheimer disease pathogenesis. Nat. Rev. Neurosci. 17 (2016), 201–207.
-
(2016)
Nat. Rev. Neurosci.
, vol.17
, pp. 201-207
-
-
Colonna, M.1
Wang, Y.2
-
47
-
-
79961234274
-
Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease
-
47 Mildner, A., et al. Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease. J. Neurosci. 31 (2011), 11159–11171.
-
(2011)
J. Neurosci.
, vol.31
, pp. 11159-11171
-
-
Mildner, A.1
-
48
-
-
84968764145
-
TREM2 haplodeficiency in mice and humans impairs the microglia barrier function leading to decreased amyloid compaction and severe axonal dystrophy
-
48 Yuan, P., et al. TREM2 haplodeficiency in mice and humans impairs the microglia barrier function leading to decreased amyloid compaction and severe axonal dystrophy. Neuron 90 (2016), 724–739.
-
(2016)
Neuron
, vol.90
, pp. 724-739
-
-
Yuan, P.1
-
49
-
-
84969286765
-
TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques
-
49 Wang, Y., et al. TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques. J. Exp. Med. 213 (2016), 667–675.
-
(2016)
J. Exp. Med.
, vol.213
, pp. 667-675
-
-
Wang, Y.1
-
50
-
-
84885356418
-
A deficiency in CCR2+ monocytes: the hidden side of Alzheimer's disease
-
50 Naert, G., Rivest, S., A deficiency in CCR2+ monocytes: the hidden side of Alzheimer's disease. J. Mol. Cell Biol. 5 (2013), 284–293.
-
(2013)
J. Mol. Cell Biol.
, vol.5
, pp. 284-293
-
-
Naert, G.1
Rivest, S.2
-
51
-
-
44949173099
-
Blocking TGF-β–Smad2/3 innate immune signaling mitigates Alzheimer-like pathology
-
51 Town, T., et al. Blocking TGF-β–Smad2/3 innate immune signaling mitigates Alzheimer-like pathology. Nat. Med. 14 (2008), 681–687.
-
(2008)
Nat. Med.
, vol.14
, pp. 681-687
-
-
Town, T.1
-
52
-
-
59049104731
-
Selective targeting of perivascular macrophages for clearance of β-amyloid in cerebral amyloid angiopathy
-
52 Hawkes, C.A., McLaurin, J., Selective targeting of perivascular macrophages for clearance of β-amyloid in cerebral amyloid angiopathy. Proc. Natl. Acad. Sci. 106 (2009), 1261–1266.
-
(2009)
Proc. Natl. Acad. Sci.
, vol.106
, pp. 1261-1266
-
-
Hawkes, C.A.1
McLaurin, J.2
-
53
-
-
34147115541
-
Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease
-
53 El Khoury, J., et al. Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease. Nat. Med. 13 (2007), 432–438.
-
(2007)
Nat. Med.
, vol.13
, pp. 432-438
-
-
El Khoury, J.1
-
54
-
-
84939525561
-
Therapeutic effects of glatiramer acetate and grafted CD115(+) monocytes in a mouse model of Alzheimer's disease
-
54 Koronyo, Y., et al. Therapeutic effects of glatiramer acetate and grafted CD115(+) monocytes in a mouse model of Alzheimer's disease. Brain 138:Pt 8 (2015), 2399–2422.
-
(2015)
Brain
, vol.138
, pp. 2399-2422
-
-
Koronyo, Y.1
-
55
-
-
70450215332
-
Attenuation of AD-like neuropathology by harnessing peripheral immune cells: local elevation of IL-10 and MMP-9
-
55 Koronyo-Hamaoui, M., et al. Attenuation of AD-like neuropathology by harnessing peripheral immune cells: local elevation of IL-10 and MMP-9. J. Neurochem. 111 (2009), 1409–1424.
-
(2009)
J. Neurochem.
, vol.111
, pp. 1409-1424
-
-
Koronyo-Hamaoui, M.1
-
56
-
-
32344440522
-
Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease
-
56 Simard, A.R., et al. Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease. Neuron 49 (2006), 489–502.
-
(2006)
Neuron
, vol.49
, pp. 489-502
-
-
Simard, A.R.1
-
57
-
-
84896692474
-
Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior
-
57 Zhan, Y., et al. Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior. Nat. Neurosci. 17 (2014), 400–406.
-
(2014)
Nat. Neurosci.
, vol.17
, pp. 400-406
-
-
Zhan, Y.1
-
58
-
-
80053390173
-
Long term potentiation is impaired in membrane glycoprotein CD200-deficient mice a role for toll-like receptor activation
-
58 Costello, D.A., et al. Long term potentiation is impaired in membrane glycoprotein CD200-deficient mice a role for toll-like receptor activation. J. Biol. Chem. 286 (2011), 34722–34732.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 34722-34732
-
-
Costello, D.A.1
-
59
-
-
84922064574
-
IL-10 alters immunoproteostasis in APP mice, increasing plaque burden and worsening cognitive behavior
-
59 Chakrabarty, P., et al. IL-10 alters immunoproteostasis in APP mice, increasing plaque burden and worsening cognitive behavior. Neuron 85 (2015), 519–533.
-
(2015)
Neuron
, vol.85
, pp. 519-533
-
-
Chakrabarty, P.1
-
60
-
-
84922026428
-
Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology
-
60 Guillot-Sestier, M-V., et al. Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology. Neuron 85 (2015), 534–548.
-
(2015)
Neuron
, vol.85
, pp. 534-548
-
-
Guillot-Sestier, M.-V.1
-
61
-
-
78651473243
-
Neuroprotection and progenitor cell renewal in the injured adult murine retina requires healing monocyte-derived macrophages
-
61 London, A., et al. Neuroprotection and progenitor cell renewal in the injured adult murine retina requires healing monocyte-derived macrophages. J. Exp. Med. 208 (2011), 23–39.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 23-39
-
-
London, A.1
-
62
-
-
84904994770
-
CNS repair requires both effector and regulatory T cells with distinct temporal and spatial profiles
-
62 Raposo, C., et al. CNS repair requires both effector and regulatory T cells with distinct temporal and spatial profiles. J. Neurosci. 34 (2014), 10141–10155.
-
(2014)
J. Neurosci.
, vol.34
, pp. 10141-10155
-
-
Raposo, C.1
-
63
-
-
84928586698
-
Astrocyte-derived TGF-β1 accelerates disease progression in ALS mice by interfering with the neuroprotective functions of microglia and T cells
-
63 Endo, F., et al. Astrocyte-derived TGF-β1 accelerates disease progression in ALS mice by interfering with the neuroprotective functions of microglia and T cells. Cell Rep. 11 (2015), 592–604.
-
(2015)
Cell Rep.
, vol.11
, pp. 592-604
-
-
Endo, F.1
-
64
-
-
84929340491
-
Immunization with a myelin-derived antigen activates the brain's choroid plexus for recruitment of immunoregulatory cells to the CNS and attenuates disease progression in a mouse model of ALS
-
64 Kunis, G., et al. Immunization with a myelin-derived antigen activates the brain's choroid plexus for recruitment of immunoregulatory cells to the CNS and attenuates disease progression in a mouse model of ALS. J. Neurosci. 35 (2015), 6381–6393.
-
(2015)
J. Neurosci.
, vol.35
, pp. 6381-6393
-
-
Kunis, G.1
-
65
-
-
84868535759
-
Progressive multiple sclerosis: pathology and pathogenesis
-
65 Lassmann, H., et al. Progressive multiple sclerosis: pathology and pathogenesis. Nat. Rev. Neurol. 8 (2012), 647–656.
-
(2012)
Nat. Rev. Neurol.
, vol.8
, pp. 647-656
-
-
Lassmann, H.1
-
66
-
-
79952126441
-
Tissue-based class control: the other side of tolerance
-
66 Matzinger, P., Kamala, T., Tissue-based class control: the other side of tolerance. Nat. Rev. Immunol. 11 (2011), 221–230.
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 221-230
-
-
Matzinger, P.1
Kamala, T.2
-
67
-
-
84887057618
-
IFN-gamma-dependent activation of the brain's choroid plexus for CNS immune surveillance and repair
-
67 Kunis, G., et al. IFN-gamma-dependent activation of the brain's choroid plexus for CNS immune surveillance and repair. Brain 136:Pt 11 (2013), 3427–3440.
-
(2013)
Brain
, vol.136
, pp. 3427-3440
-
-
Kunis, G.1
-
68
-
-
84933674972
-
Cerebral nitric oxide represses choroid plexus NFκB - dependent gateway activity for leukocyte trafficking
-
68 Baruch, K., et al. Cerebral nitric oxide represses choroid plexus NFκB - dependent gateway activity for leukocyte trafficking. EMBO J., 2015, e201591468.
-
(2015)
EMBO J.
, pp. e201591468
-
-
Baruch, K.1
-
69
-
-
84875414225
-
Orchestrated leukocyte recruitment to immune-privileged sites: absolute barriers versus educational gates
-
69 Shechter, R., et al. Orchestrated leukocyte recruitment to immune-privileged sites: absolute barriers versus educational gates. Nat. Rev. Immunol. 13 (2013), 206–218.
-
(2013)
Nat. Rev. Immunol.
, vol.13
, pp. 206-218
-
-
Shechter, R.1
-
70
-
-
84963841577
-
Origin, fate and dynamics of macrophages at central nervous system interfaces
-
70 Goldmann, T., et al. Origin, fate and dynamics of macrophages at central nervous system interfaces. Nat. Immunol. 17 (2016), 797–805.
-
(2016)
Nat. Immunol.
, vol.17
, pp. 797-805
-
-
Goldmann, T.1
-
71
-
-
77952311924
-
Regulation of learning and memory by meningeal immunity: a key role for IL-4
-
71 Derecki, N.C., et al. Regulation of learning and memory by meningeal immunity: a key role for IL-4. J. Exp. Med. 207 (2010), 1067–1080.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 1067-1080
-
-
Derecki, N.C.1
-
72
-
-
84899488296
-
Dynamics of the meningeal CD4(+) T-cell repertoire are defined by the cervical lymph nodes and facilitate cognitive task performance in mice
-
72 Radjavi, A., et al. Dynamics of the meningeal CD4(+) T-cell repertoire are defined by the cervical lymph nodes and facilitate cognitive task performance in mice. Mol. Psychiatry 19 (2014), 531–533.
-
(2014)
Mol. Psychiatry
, vol.19
, pp. 531-533
-
-
Radjavi, A.1
-
73
-
-
84888880129
-
Brain antigen-reactive CD4+ T cells are sufficient to support learning behavior in mice with limited T cell repertoire
-
73 Radjavi, A., et al. Brain antigen-reactive CD4+ T cells are sufficient to support learning behavior in mice with limited T cell repertoire. Brain Behav. Immun. 35 (2014), 58–63.
-
(2014)
Brain Behav. Immun.
, vol.35
, pp. 58-63
-
-
Radjavi, A.1
-
74
-
-
65549167413
-
Kinetic profile of the transcriptome changes induced in the choroid plexus by peripheral inflammation
-
74 Marques, F., et al. Kinetic profile of the transcriptome changes induced in the choroid plexus by peripheral inflammation. J. Cereb. Blood Flow Metab. 29 (2009), 921–932.
-
(2009)
J. Cereb. Blood Flow Metab.
, vol.29
, pp. 921-932
-
-
Marques, F.1
-
75
-
-
71549130733
-
The choroid plexus response to a repeated peripheral inflammatory stimulus
-
75 Marques, F., et al. The choroid plexus response to a repeated peripheral inflammatory stimulus. BMC Neurosci., 10, 2009, 135.
-
(2009)
BMC Neurosci.
, vol.10
, pp. 135
-
-
Marques, F.1
-
76
-
-
84876804888
-
The path from the choroid plexus to the subventricular zone: go with the flow!
-
76 Falcao, A.M., et al. The path from the choroid plexus to the subventricular zone: go with the flow!. Front. Cell. Neurosci., 6, 2012, 34.
-
(2012)
Front. Cell. Neurosci.
, vol.6
, pp. 34
-
-
Falcao, A.M.1
-
77
-
-
15944418259
-
The choroid plexus in the rise, fall and repair of the brain
-
77 Emerich, D.F., et al. The choroid plexus in the rise, fall and repair of the brain. Bioessays 27 (2005), 262–274.
-
(2005)
Bioessays
, vol.27
, pp. 262-274
-
-
Emerich, D.F.1
-
78
-
-
79951682931
-
The blood-cerebrospinal fluid barrier: structure and functional significance
-
78 Johanson, C.E., et al. The blood-cerebrospinal fluid barrier: structure and functional significance. Methods Mol. Biol. 686 (2011), 101–131.
-
(2011)
Methods Mol. Biol.
, vol.686
, pp. 101-131
-
-
Johanson, C.E.1
-
79
-
-
84868088436
-
Cell trafficking through the choroid plexus
-
79 Meeker, R.B., et al. Cell trafficking through the choroid plexus. Cell Adh. Migr. 6 (2012), 390–396.
-
(2012)
Cell Adh. Migr.
, vol.6
, pp. 390-396
-
-
Meeker, R.B.1
-
80
-
-
0029952623
-
ICAM-1, VCAM-1, and MAdCAM-1 are expressed on choroid plexus epithelium but not endothelium and mediate binding of lymphocytes in vitro
-
80 Steffen, B.J., et al. ICAM-1, VCAM-1, and MAdCAM-1 are expressed on choroid plexus epithelium but not endothelium and mediate binding of lymphocytes in vitro. Am. J. Pathol., 148, 1996, 1819.
-
(1996)
Am. J. Pathol.
, vol.148
, pp. 1819
-
-
Steffen, B.J.1
-
81
-
-
84959315169
-
Type I/II interferon balance in the regulation of brain physiology and pathology
-
81 Deczkowska, A., et al. Type I/II interferon balance in the regulation of brain physiology and pathology. Trends Immunol. 37 (2016), 181–192.
-
(2016)
Trends Immunol.
, vol.37
, pp. 181-192
-
-
Deczkowska, A.1
-
82
-
-
84873475219
-
CNS-specific immunity at the choroid plexus shifts toward destructive Th2 inflammation in brain aging
-
82 Baruch, K., et al. CNS-specific immunity at the choroid plexus shifts toward destructive Th2 inflammation in brain aging. Proc. Natl. Acad. Sci. U.S.A. 110 (2013), 2264–2269.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 2264-2269
-
-
Baruch, K.1
-
83
-
-
79551554496
-
Resident memory T cells (T RM) are abundant in human lung: diversity, function, and antigen specificity
-
83 Purwar, R., et al. Resident memory T cells (T RM) are abundant in human lung: diversity, function, and antigen specificity. PloS ONE, 6, 2011, e16245.
-
(2011)
PloS ONE
, vol.6
, pp. e16245
-
-
Purwar, R.1
-
84
-
-
65249175159
-
CC chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE
-
84 Reboldi, A., et al. CC chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE. Nat. Immunol. 10 (2009), 514–523.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 514-523
-
-
Reboldi, A.1
-
85
-
-
84940599385
-
The choroid plexus transcriptome reveals changes in type I and II interferon responses in a mouse model of Alzheimer's disease
-
85 Mesquita, S.D., et al. The choroid plexus transcriptome reveals changes in type I and II interferon responses in a mouse model of Alzheimer's disease. Brain Behav. Immun. 49 (2015), 280–292.
-
(2015)
Brain Behav. Immun.
, vol.49
, pp. 280-292
-
-
Mesquita, S.D.1
-
86
-
-
84901430100
-
Aging is associated with increased regulatory T - cell function
-
86 Garg, S.K., et al. Aging is associated with increased regulatory T - cell function. Aging Cell 13 (2014), 441–448.
-
(2014)
Aging Cell
, vol.13
, pp. 441-448
-
-
Garg, S.K.1
-
87
-
-
0030925868
-
Th1/Th2 changes in aging
-
87 Shearer, G.M., Th1/Th2 changes in aging. Mech. Ageing Dev. 94 (1997), 1–5.
-
(1997)
Mech. Ageing Dev.
, vol.94
, pp. 1-5
-
-
Shearer, G.M.1
-
88
-
-
84907659600
-
Aging. Aging-induced type I interferon response at the choroid plexus negatively affects brain function
-
88 Baruch, K., et al. Aging. Aging-induced type I interferon response at the choroid plexus negatively affects brain function. Science 346 (2014), 89–93.
-
(2014)
Science
, vol.346
, pp. 89-93
-
-
Baruch, K.1
-
89
-
-
34447644067
-
Selective ablation of bone marrow-derived dendritic cells increases amyloid plaques in a mouse Alzheimer's disease model
-
89 Butovsky, O., et al. Selective ablation of bone marrow-derived dendritic cells increases amyloid plaques in a mouse Alzheimer's disease model. Eur. J. Neurosci. 26 (2007), 413–416.
-
(2007)
Eur. J. Neurosci.
, vol.26
, pp. 413-416
-
-
Butovsky, O.1
-
90
-
-
58549098084
-
Blood–brain barrier: ageing and microvascular disease–systematic review and meta-analysis
-
90 Farrall, A.J., Wardlaw, J.M., Blood–brain barrier: ageing and microvascular disease–systematic review and meta-analysis. Neurobiol. Aging 30 (2009), 337–352.
-
(2009)
Neurobiol. Aging
, vol.30
, pp. 337-352
-
-
Farrall, A.J.1
Wardlaw, J.M.2
-
91
-
-
84875553508
-
Recruitment of beneficial M2 macrophages to injured spinal cord is orchestrated by remote brain choroid plexus
-
91 Shechter, R., et al. Recruitment of beneficial M2 macrophages to injured spinal cord is orchestrated by remote brain choroid plexus. Immunity 38 (2013), 555–569.
-
(2013)
Immunity
, vol.38
, pp. 555-569
-
-
Shechter, R.1
-
92
-
-
0037097215
-
Monocyte recruitment and myelin removal are delayed following spinal cord injury in mice with CCR2 chemokine receptor deletion
-
92 Ma, M., et al. Monocyte recruitment and myelin removal are delayed following spinal cord injury in mice with CCR2 chemokine receptor deletion. J. Neurosci. Res. 68 (2002), 691–702.
-
(2002)
J. Neurosci. Res.
, vol.68
, pp. 691-702
-
-
Ma, M.1
-
93
-
-
0032146758
-
Selective chemokine mRNA accumulation in the rat spinal cord after contusion injury
-
93 McTigue, D.M., et al. Selective chemokine mRNA accumulation in the rat spinal cord after contusion injury. J. Neurosci. Res. 53 (1998), 368–376.
-
(1998)
J. Neurosci. Res.
, vol.53
, pp. 368-376
-
-
McTigue, D.M.1
-
94
-
-
84896752215
-
Immune cell trafficking from the brain maintains CNS immune tolerance
-
94 Mohammad, M.G., et al. Immune cell trafficking from the brain maintains CNS immune tolerance. J. Clin. Invest. 124 (2014), 1228–1241.
-
(2014)
J. Clin. Invest.
, vol.124
, pp. 1228-1241
-
-
Mohammad, M.G.1
-
95
-
-
84942469639
-
A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules
-
95 Aspelund, A., et al. A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules. J. Exp. Med. 212 (2015), 991–999.
-
(2015)
J. Exp. Med.
, vol.212
, pp. 991-999
-
-
Aspelund, A.1
-
96
-
-
84936871460
-
Structural and functional features of central nervous system lymphatic vessels
-
96 Louveau, A., et al. Structural and functional features of central nervous system lymphatic vessels. Nature 523 (2015), 337–341.
-
(2015)
Nature
, vol.523
, pp. 337-341
-
-
Louveau, A.1
-
97
-
-
84983130412
-
Understanding the role of T cells in CNS homeostasis
-
97 Ellwardt, E., et al. Understanding the role of T cells in CNS homeostasis. Trends Immunol. 37 (2016), 154–165.
-
(2016)
Trends Immunol.
, vol.37
, pp. 154-165
-
-
Ellwardt, E.1
-
98
-
-
57049154546
-
Lymphatic drainage of the brain and the pathophysiology of neurological disease
-
98 Weller, R.O., et al. Lymphatic drainage of the brain and the pathophysiology of neurological disease. Acta Neuropathol. 117 (2009), 1–14.
-
(2009)
Acta Neuropathol.
, vol.117
, pp. 1-14
-
-
Weller, R.O.1
-
99
-
-
84882273124
-
Drainage of cells and soluble antigen from the CNS to regional lymph nodes
-
99 Laman, J.D., Weller, R.O., Drainage of cells and soluble antigen from the CNS to regional lymph nodes. J. Neuroimmune Pharmacol. 8 (2013), 840–856.
-
(2013)
J. Neuroimmune Pharmacol.
, vol.8
, pp. 840-856
-
-
Laman, J.D.1
Weller, R.O.2
-
100
-
-
84924716458
-
Multiple sclerosis — a quiet revolution
-
100 Ransohoff, R.M., et al. Multiple sclerosis — a quiet revolution. Nat. Rev. Neurol. 11 (2015), 134–142.
-
(2015)
Nat. Rev. Neurol.
, vol.11
, pp. 134-142
-
-
Ransohoff, R.M.1
-
101
-
-
85010046415
-
A real world experience with fingolimod in active RRMS patients naïve to second-line agents: a 2 years, intention-to-treat, observational, single center study
-
101 Baroncini, D., et al. A real world experience with fingolimod in active RRMS patients naïve to second-line agents: a 2 years, intention-to-treat, observational, single center study. Multiple Sclerosis and Demyelinating Disorders, 1, 2016, 1.
-
(2016)
Multiple Sclerosis and Demyelinating Disorders
, vol.1
, pp. 1
-
-
Baroncini, D.1
-
102
-
-
0033536163
-
Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse
-
102 Schenk, D., et al. Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature 400 (1999), 173–177.
-
(1999)
Nature
, vol.400
, pp. 173-177
-
-
Schenk, D.1
-
103
-
-
0034700471
-
Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
-
103 Janus, C., et al. Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease. Nature 408 (2000), 979–982.
-
(2000)
Nature
, vol.408
, pp. 979-982
-
-
Janus, C.1
-
104
-
-
34848885871
-
Mechanism of action of glatiramer acetate in treatment of multiple sclerosis
-
104 Weber, M.S., et al. Mechanism of action of glatiramer acetate in treatment of multiple sclerosis. Neurotherapeutics 4 (2007), 647–653.
-
(2007)
Neurotherapeutics
, vol.4
, pp. 647-653
-
-
Weber, M.S.1
-
105
-
-
0842331842
-
Immunomodulation by the copolymer glatiramer acetate
-
105 Arnon, R., Sela, M., Immunomodulation by the copolymer glatiramer acetate. J. Mol. Recogn. 16 (2003), 412–421.
-
(2003)
J. Mol. Recogn.
, vol.16
, pp. 412-421
-
-
Arnon, R.1
Sela, M.2
-
106
-
-
70449697216
-
Glatiramer acetate has no impact on disease progression in ALS at 40 mg/day: a double-blind, randomized, multicentre, placebo-controlled trial
-
106 Meininger, V., et al. Glatiramer acetate has no impact on disease progression in ALS at 40 mg/day: a double-blind, randomized, multicentre, placebo-controlled trial. Amyotroph. Lateral Scler. 10 (2009), 378–383.
-
(2009)
Amyotroph. Lateral Scler.
, vol.10
, pp. 378-383
-
-
Meininger, V.1
-
107
-
-
84922423174
-
Therapeutic uses of anti-α4-integrin (anti-VLA-4) antibodies in multiple sclerosis
-
107 Schwab, N., et al. Therapeutic uses of anti-α4-integrin (anti-VLA-4) antibodies in multiple sclerosis. Int. Immunol. 27 (2015), 47–53.
-
(2015)
Int. Immunol.
, vol.27
, pp. 47-53
-
-
Schwab, N.1
-
108
-
-
0026506799
-
Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin
-
108 Yednock, T.A., et al. Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin. Nature 356 (1992), 63–66.
-
(1992)
Nature
, vol.356
, pp. 63-66
-
-
Yednock, T.A.1
-
109
-
-
84861955413
-
Progressive multiple sclerosis: The treatment gap
-
S10-S10
-
109 Humphries, C., Progressive multiple sclerosis: The treatment gap. Nature, 484, 2012 S10-S10.
-
(2012)
Nature
, vol.484
-
-
Humphries, C.1
-
110
-
-
40449089827
-
Differential regulation of central nervous system autoimmunity by TH1 and TH17 cells
-
110 Stromnes, I.M., et al. Differential regulation of central nervous system autoimmunity by TH1 and TH17 cells. Nat. Med. 14 (2008), 337–342.
-
(2008)
Nat. Med.
, vol.14
, pp. 337-342
-
-
Stromnes, I.M.1
-
111
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
-
111 Hardy, J., Selkoe, D.J., The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297 (2002), 353–356.
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
112
-
-
33645470003
-
Neuropathologic changes in Alzheimer's disease: potential targets for treatment
-
quiz 23
-
112 Wenk, G.L., Neuropathologic changes in Alzheimer's disease: potential targets for treatment. J. Clin. Psychiatry 67:Suppl. 3 (2006), 3–7 quiz 23.
-
(2006)
J. Clin. Psychiatry
, vol.67
, pp. 3-7
-
-
Wenk, G.L.1
-
113
-
-
51149120624
-
Microglial dysfunction and defective β-amyloid clearance pathways in aging Alzheimer's disease mice
-
113 Hickman, S.E., et al. Microglial dysfunction and defective β-amyloid clearance pathways in aging Alzheimer's disease mice. J. Neurosci. 28 (2008), 8354–8360.
-
(2008)
J. Neurosci.
, vol.28
, pp. 8354-8360
-
-
Hickman, S.E.1
-
114
-
-
34248355132
-
Loss of blood–brain barrier integrity in the spinal cord is common to experimental allergic encephalomyelitis in knockout mouse models
-
114 Fabis, M.J., et al. Loss of blood–brain barrier integrity in the spinal cord is common to experimental allergic encephalomyelitis in knockout mouse models. Proc. Natl. Acad. Sci. U.S.A. 104 (2007), 5656–5661.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 5656-5661
-
-
Fabis, M.J.1
-
115
-
-
0035153262
-
Involvement of the choroid plexus in central nervous system inflammation
-
115 Engelhardt, B., et al. Involvement of the choroid plexus in central nervous system inflammation. Microsc. Res. Tech. 52 (2001), 112–129.
-
(2001)
Microsc. Res. Tech.
, vol.52
, pp. 112-129
-
-
Engelhardt, B.1
-
116
-
-
72949119691
-
Management of acute exacerbations in multiple sclerosis
-
116 Ontaneda, D., Rae-Grant, A.D., Management of acute exacerbations in multiple sclerosis. Ann. Indian Acad. Neurol. 12 (2009), 264–272.
-
(2009)
Ann. Indian Acad. Neurol.
, vol.12
, pp. 264-272
-
-
Ontaneda, D.1
Rae-Grant, A.D.2
|