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Volumn 138, Issue 8, 2015, Pages 2399-2422

Therapeutic effects of glatiramer acetate and grafted CD115+ monocytes in a mouse model of Alzheimer's disease

Author keywords

Alzheimer's disease; behavioural neurology; dementia; neuroinflammation; neuroprotection

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; CD36 ANTIGEN; GELATINASE B; GLATIRAMER; GREEN FLUORESCENT PROTEIN; INTERLEUKIN 10; PHOSPHATE BUFFERED SALINE; PROTEIN SCARA1; SCAVENGER RECEPTOR; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; COLONY STIMULATING FACTOR RECEPTOR;

EID: 84939525561     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awv150     Document Type: Article
Times cited : (127)

References (66)
  • 1
    • 34548479478 scopus 로고    scopus 로고
    • The therapeutic effect of glatiramer acetate in a murine model of inflammatory bowel disease is mediated by anti-inflammatory T-cells
    • Aharoni R, Sonego H, Brenner O, Eilam R, Arnon R. The therapeutic effect of glatiramer acetate in a murine model of inflammatory bowel disease is mediated by anti-inflammatory T-cells. Immunol Lett 2007; 112: 110-9.
    • (2007) Immunol Lett , vol.112 , pp. 110-119
    • Aharoni, R.1    Sonego, H.2    Brenner, O.3    Eilam, R.4    Arnon, R.5
  • 4
    • 5144233487 scopus 로고    scopus 로고
    • Mechanism of action of glatiramer acetate in multiple sclerosis and its potential for the development of new applications
    • Arnon R, Aharoni R. Mechanism of action of glatiramer acetate in multiple sclerosis and its potential for the development of new applications. Proc Natl Acad Sci USA 2004; 101 (Suppl 2): 14593-8.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 14593-14598
    • Arnon, R.1    Aharoni, R.2
  • 5
    • 84856023786 scopus 로고    scopus 로고
    • Egr1 expression is induced following glatiramer acetate immunotherapy in rodent models of glaucoma and Alzheimer's disease
    • Bakalash S, Pham M, Koronyo Y, Salumbides BC, Kramerov A, Seidenberg H, et al. Egr1 expression is induced following glatiramer acetate immunotherapy in rodent models of glaucoma and Alzheimer's disease. Invest Ophthalmol Vis Sci 2011; 52: 9033-46.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 9033-9046
    • Bakalash, S.1    Pham, M.2    Koronyo, Y.3    Salumbides, B.C.4    Kramerov, A.5    Seidenberg, H.6
  • 6
    • 0034611980 scopus 로고    scopus 로고
    • Neuroinflammation and Alzheimer's disease: Critical roles for cytokine/Abeta-induced glial activation, NF-kappaB, and apolipoprotein E
    • Bales KR, Du Y, Holtzman D, Cordell B, Paul SM. Neuroinflammation and Alzheimer's disease: critical roles for cytokine/Abeta-induced glial activation, NF-kappaB, and apolipoprotein E. Neurobiol Aging 2000; 21: 427-32.
    • (2000) Neurobiol Aging , vol.21 , pp. 427-432
    • Bales, K.R.1    Du, Y.2    Holtzman, D.3    Cordell, B.4    Paul, S.M.5
  • 7
    • 67349093525 scopus 로고    scopus 로고
    • Clearance mechanisms of Alzheimer's amyloid-beta peptide: Implications for therapeutic design and diagnostic tests
    • Bates KA, Verdile G, Li QX, Ames D, Hudson P, Masters CL, et al. Clearance mechanisms of Alzheimer's amyloid-beta peptide: implications for therapeutic design and diagnostic tests. Mol Psychiatry 2009; 14: 469-86.
    • (2009) Mol Psychiatry , vol.14 , pp. 469-486
    • Bates, K.A.1    Verdile, G.2    Li, Q.X.3    Ames, D.4    Hudson, P.5    Masters, C.L.6
  • 8
    • 84896799922 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme overexpression in myelomonocytes prevents Alzheimer's-like cognitive decline
    • Bernstein KE, Koronyo Y, Salumbides BC, Sheyn J, Pelissier L, Lopes DH, et al. Angiotensin-converting enzyme overexpression in myelomonocytes prevents Alzheimer's-like cognitive decline. J Clin Invest 2014; 124: 1000-12.
    • (2014) J Clin Invest , vol.124 , pp. 1000-1012
    • Bernstein, K.E.1    Koronyo, Y.2    Salumbides, B.C.3    Sheyn, J.4    Pelissier, L.5    Lopes, D.H.6
  • 9
    • 65249119363 scopus 로고    scopus 로고
    • Powerful beneficial effects of macrophage colony-stimulating factor on beta-amyloid deposition and cognitive impairment in Alzheimer's disease
    • Boissonneault V, Filali M, Lessard M, Relton J, Wong G, Rivest S. Powerful beneficial effects of macrophage colony-stimulating factor on beta-amyloid deposition and cognitive impairment in Alzheimer's disease. Brain 2009; 132: 1078-92.
    • (2009) Brain , vol.132 , pp. 1078-1092
    • Boissonneault, V.1    Filali, M.2    Lessard, M.3    Relton, J.4    Wong, G.5    Rivest, S.6
  • 10
    • 33746827434 scopus 로고    scopus 로고
    • Glatiramer acetate fights against Alzheimer's disease by inducing dendritic-like microglia expressing insulin-like growth factor 1
    • Butovsky O, Koronyo-Hamaoui M, Kunis G, Ophir E, Landa G, Cohen H, et al. Glatiramer acetate fights against Alzheimers disease by inducing dendritic-like microglia expressing insulin-like growth factor 1. Proc Natl Acad Sci USA 2006; 103: 11784-9.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 11784-11789
    • Butovsky, O.1    Koronyo-Hamaoui, M.2    Kunis, G.3    Ophir, E.4    Landa, G.5    Cohen, H.6
  • 11
    • 34447644067 scopus 로고    scopus 로고
    • Selective ablation of bone marrow-derived dendritic cells increases amyloid plaques in a mouse Alzheimer's disease model
    • Butovsky O, Kunis G, Koronyo-Hamaoui M, Schwartz M. Selective ablation of bone marrow-derived dendritic cells increases amyloid plaques in a mouse Alzheimer's disease model. Eur J Neurosci 2007; 26: 413-6.
    • (2007) Eur J Neurosci , vol.26 , pp. 413-416
    • Butovsky, O.1    Kunis, G.2    Koronyo-Hamaoui, M.3    Schwartz, M.4
  • 12
    • 0026484136 scopus 로고
    • Astrocytosis, beta A4-protein deposition and paired helical filament formation in Alzheimer's disease
    • Cairns NJ, Chadwick A, Luthert PJ, Lantos PL. Astrocytosis, beta A4-protein deposition and paired helical filament formation in Alzheimer's disease. J Neurol Sci 1992; 112: 68-75.
    • (1992) J Neurol Sci , vol.112 , pp. 68-75
    • Cairns, N.J.1    Chadwick, A.2    Luthert, P.J.3    Lantos, P.L.4
  • 14
    • 34147115541 scopus 로고    scopus 로고
    • Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease
    • El Khoury J, Toft M, Hickman SE, Means TK, Terada K, Geula C, et al. Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease. Nat Med 2007; 13: 432-8.
    • (2007) Nat Med , vol.13 , pp. 432-438
    • El Khoury, J.1    Toft, M.2    Hickman, S.E.3    Means, T.K.4    Terada, K.5    Geula, C.6
  • 15
    • 34447636918 scopus 로고    scopus 로고
    • Phagocytosis of amyloid-beta and inflammation: Two faces of innate immunity in Alzheimer's disease
    • Fiala M, Cribbs DH, Rosenthal M, Bernard G. Phagocytosis of amyloid-beta and inflammation: two faces of innate immunity in Alzheimer's disease. J Alzheimers Dis 2007; 11: 457-63.
    • (2007) J Alzheimers Dis , vol.11 , pp. 457-463
    • Fiala, M.1    Cribbs, D.H.2    Rosenthal, M.3    Bernard, G.4
  • 16
    • 21444454120 scopus 로고    scopus 로고
    • Ineffective phagocytosis of amyloid-beta by macrophages of Alzheimer's disease patients
    • discussion 255-62
    • Fiala M, Lin J, Ringman J, Kermani-Arab V, Tsao G, Patel A, et al. Ineffective phagocytosis of amyloid-beta by macrophages of Alzheimer's disease patients. J Alzheimers Dis 2005; 7: 221-32; discussion 255-62.
    • (2005) J Alzheimers Dis , vol.7 , pp. 221-232
    • Fiala, M.1    Lin, J.2    Ringman, J.3    Kermani-Arab, V.4    Tsao, G.5    Patel, A.6
  • 17
    • 0029002659 scopus 로고
    • Normal adult ramified microglia separated from other central nervous system macrophages by flow cytometric sorting. Phenotypic differences defined and direct ex vivo antigen presentation to myelin basic protein-reactive CD4 + T cells compared
    • Ford AL, Goodsall AL, Hickey WF, Sedgwick JD. Normal adult ramified microglia separated from other central nervous system macrophages by flow cytometric sorting. Phenotypic differences defined and direct ex vivo antigen presentation to myelin basic protein-reactive CD4 + T cells compared. J Immunol 1995; 154: 4309-21.
    • (1995) J Immunol , vol.154 , pp. 4309-4321
    • Ford, A.L.1    Goodsall, A.L.2    Hickey, W.F.3    Sedgwick, J.D.4
  • 18
    • 0026635173 scopus 로고
    • Phagocytosis and deposition of vascular beta-amyloid in rat brains injected with Alzheimer beta-amyloid
    • Frautschy SA, Cole GM, Baird A. Phagocytosis and deposition of vascular beta-amyloid in rat brains injected with Alzheimer beta-amyloid. Am J Pathol 1992; 140: 1389-99.
    • (1992) Am J Pathol , vol.140 , pp. 1389-1399
    • Frautschy, S.A.1    Cole, G.M.2    Baird, A.3
  • 19
    • 24644435506 scopus 로고    scopus 로고
    • Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears beta-amyloid in a mouse model of Alzheimer disease
    • Frenkel D, Maron R, Burt DS, Weiner HL. Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears beta-amyloid in a mouse model of Alzheimer disease. J Clin Invest 2005; 115: 2423-33.
    • (2005) J Clin Invest , vol.115 , pp. 2423-2433
    • Frenkel, D.1    Maron, R.2    Burt, D.S.3    Weiner, H.L.4
  • 20
    • 84883361779 scopus 로고    scopus 로고
    • Scara1 deficiency impairs clearance of soluble amyloid-beta by mononuclear phagocytes and accelerates Alzheimer's-like disease progression
    • Frenkel D, Wilkinson K, Zhao L, Hickman SE, Means TK, Puckett L, et al. Scara1 deficiency impairs clearance of soluble amyloid-beta by mononuclear phagocytes and accelerates Alzheimer's-like disease progression. Nat Commun 2013; 4: 2030.
    • (2013) Nat Commun , vol.4 , pp. 2030
    • Frenkel, D.1    Wilkinson, K.2    Zhao, L.3    Hickman, S.E.4    Means, T.K.5    Puckett, L.6
  • 21
    • 34547127632 scopus 로고    scopus 로고
    • Neuroprotective role of the innate immune system by microglia
    • Glezer I, Simard AR, Rivest S. Neuroprotective role of the innate immune system by microglia. Neuroscience 2007; 147: 867-83.
    • (2007) Neuroscience , vol.147 , pp. 867-883
    • Glezer, I.1    Simard, A.R.2    Rivest, S.3
  • 22
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
    • Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 2002; 297: 353-6.
    • (2002) Science , vol.297 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 23
    • 59049104731 scopus 로고    scopus 로고
    • Selective targeting of perivascular macrophages for clearance of beta-amyloid in cerebral amyloid angiopathy
    • Hawkes CA, McLaurin J. Selective targeting of perivascular macrophages for clearance of beta-amyloid in cerebral amyloid angiopathy. Proc Natl Acad Sci USA 2009; 106: 1261-6.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 1261-1266
    • Hawkes, C.A.1    McLaurin, J.2
  • 24
    • 51149120624 scopus 로고    scopus 로고
    • Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer's disease mice
    • Hickman SE, Allison EK, El Khoury J. Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer's disease mice. J Neurosci 2008; 28: 8354-60.
    • (2008) J Neurosci , vol.28 , pp. 8354-8360
    • Hickman, S.E.1    Allison, E.K.2    El Khoury, J.3
  • 25
    • 77949890133 scopus 로고    scopus 로고
    • Mechanisms of mononuclear phagocyte recruitment in Alzheimer's disease
    • Hickman SE, El Khoury J. Mechanisms of mononuclear phagocyte recruitment in Alzheimer's disease. CNS Neurol Disord Drug Targets 2010; 9: 168-73.
    • (2010) CNS Neurol Disord Drug Targets , vol.9 , pp. 168-173
    • Hickman, S.E.1    El Khoury, J.2
  • 26
    • 0034596949 scopus 로고    scopus 로고
    • Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2
    • Izikson L, Klein RS, Charo IF, Weiner HL, Luster AD. Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2. J Exp Med 2000; 192: 1075-80.
    • (2000) J Exp Med , vol.192 , pp. 1075-1080
    • Izikson, L.1    Klein, R.S.2    Charo, I.F.3    Weiner, H.L.4    Luster, A.D.5
  • 27
    • 1642555780 scopus 로고    scopus 로고
    • Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: Evidence for augmentation of a 42-specific gamma secretase
    • Jankowsky JL, Fadale DJ, Anderson J, Xu GM, Gonzales V, Jenkins NA, et al. Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase. Hum Mol Genet 2004; 13: 159-70.
    • (2004) Hum Mol Genet , vol.13 , pp. 159-170
    • Jankowsky, J.L.1    Fadale, D.J.2    Anderson, J.3    Xu, G.M.4    Gonzales, V.5    Jenkins, N.A.6
  • 29
    • 0035871635 scopus 로고    scopus 로고
    • Resident and infiltrating central nervous system APCs regulate the emergence and resolution of experimental autoimmune encephalomyelitis
    • Juedes AE, Ruddle NH. Resident and infiltrating central nervous system APCs regulate the emergence and resolution of experimental autoimmune encephalomyelitis. J Immunol 2001; 166: 5168-75.
    • (2001) J Immunol , vol.166 , pp. 5168-5175
    • Juedes, A.E.1    Ruddle, N.H.2
  • 30
    • 84889582306 scopus 로고    scopus 로고
    • Glial fibrillary acidic protein isoform expression in plaque related astrogliosis in Alzheimer's disease
    • Kamphuis W, Middeldorp J, Kooijman L, Sluijs JA, Kooi EJ, Moeton M, et al. Glial fibrillary acidic protein isoform expression in plaque related astrogliosis in Alzheimer's disease. Neurobiol Aging 2014; 35: 492-510.
    • (2014) Neurobiol Aging , vol.35 , pp. 492-510
    • Kamphuis, W.1    Middeldorp, J.2    Kooijman, L.3    Sluijs, J.A.4    Kooi, E.J.5    Moeton, M.6
  • 31
    • 0031927636 scopus 로고    scopus 로고
    • Confocal observation of senile plaques in Alzheimer's disease: Senile plaque morphology and relationship between senile plaques and astrocytes
    • Kato S, Gondo T, Hoshii Y, Takahashi M, Yamada M, Ishihara T. Confocal observation of senile plaques in Alzheimer's disease: senile plaque morphology and relationship between senile plaques and astrocytes. Pathol Int 1998; 48: 332-40.
    • (1998) Pathol Int , vol.48 , pp. 332-340
    • Kato, S.1    Gondo, T.2    Hoshii, Y.3    Takahashi, M.4    Yamada, M.5    Ishihara, T.6
  • 32
    • 70450215332 scopus 로고    scopus 로고
    • Attenuation of AD-like neuropathology by harnessing peripheral immune cells: Local elevation of IL-10 and MMP-9
    • Koronyo-Hamaoui M, Ko MK, Koronyo Y, Azoulay D, Seksenyan A, Kunis G, et al. Attenuation of AD-like neuropathology by harnessing peripheral immune cells: local elevation of IL-10 and MMP-9. J Neurochem 2009; 111: 1409-24.
    • (2009) J Neurochem , vol.111 , pp. 1409-1424
    • Koronyo-Hamaoui, M.1    Ko, M.K.2    Koronyo, Y.3    Azoulay, D.4    Seksenyan, A.5    Kunis, G.6
  • 33
    • 78650832181 scopus 로고    scopus 로고
    • Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model
    • Koronyo-Hamaoui M, Koronyo Y, Ljubimov AV, Miller CA, Ko MK, Black KL, et al. Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model. Neuroimage 2011; 54: S204-17.
    • (2011) Neuroimage , vol.54 , pp. S204-S217
    • Koronyo-Hamaoui, M.1    Koronyo, Y.2    Ljubimov, A.V.3    Miller, C.A.4    Ko, M.K.5    Black, K.L.6
  • 34
    • 84858259145 scopus 로고    scopus 로고
    • Clearance of amyloid-beta peptides by microglia and macrophages: The issue of what, when and where
    • Lai AY, McLaurin J. Clearance of amyloid-beta peptides by microglia and macrophages: the issue of what, when and where. Future Neurol 2012; 7: 165-76.
    • (2012) Future Neurol , vol.7 , pp. 165-176
    • Lai, A.Y.1    McLaurin, J.2
  • 35
    • 84885345875 scopus 로고    scopus 로고
    • Migration of bone marrow-derived cells into the central nervous system in models of neurodegeneration
    • Lampron A, Pimentel-Coelho PM, Rivest S. Migration of bone marrow-derived cells into the central nervous system in models of neurodegeneration. J Comp Neurol 2013; 521: 3863-76.
    • (2013) J Comp Neurol , vol.521 , pp. 3863-3876
    • Lampron, A.1    Pimentel-Coelho, P.M.2    Rivest, S.3
  • 36
    • 77954851584 scopus 로고    scopus 로고
    • Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloid-depositing transgenic mice
    • Lebson L, Nash K, Kamath S, Herber D, Carty N, Lee DC, et al. Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloid-depositing transgenic mice. J Neurosci 2010; 30: 9651-8.
    • (2010) J Neurosci , vol.30 , pp. 9651-9658
    • Lebson, L.1    Nash, K.2    Kamath, S.3    Herber, D.4    Carty, N.5    Lee, D.C.6
  • 37
    • 79951948366 scopus 로고    scopus 로고
    • Projections from the brain to the spinal cord in the mouse
    • Liang H, Paxinos G, Watson C. Projections from the brain to the spinal cord in the mouse. Brain Struct Funct 2011; 215: 159-86.
    • (2011) Brain Struct Funct , vol.215 , pp. 159-186
    • Liang, H.1    Paxinos, G.2    Watson, C.3
  • 38
    • 40849105303 scopus 로고    scopus 로고
    • Degradation of fibrillar forms of Alzheimer's amyloid beta-peptide by macrophages
    • Majumdar A, Chung H, Dolios G, Wang R, Asamoah N, Lobel P, et al. Degradation of fibrillar forms of Alzheimer's amyloid beta-peptide by macrophages. Neurobiol Aging 2008; 29: 707-15.
    • (2008) Neurobiol Aging , vol.29 , pp. 707-715
    • Majumdar, A.1    Chung, H.2    Dolios, G.3    Wang, R.4    Asamoah, N.5    Lobel, P.6
  • 39
    • 77952568975 scopus 로고    scopus 로고
    • The role and therapeutic potential of monocytic cells in Alzheimer's disease
    • Malm T, Koistinaho M, Muona A, Magga J, Koistinaho J. The role and therapeutic potential of monocytic cells in Alzheimer's disease. Glia 2010; 58: 889-900.
    • (2010) Glia , vol.58 , pp. 889-900
    • Malm, T.1    Koistinaho, M.2    Muona, A.3    Magga, J.4    Koistinaho, J.5
  • 40
    • 84871246344 scopus 로고    scopus 로고
    • Animal models of Alzheimer's disease: Utilization of transgenic Alzheimer's disease models in studies of amyloid beta clearance
    • Malm T, Magga J, Koistinaho J. Animal models of Alzheimer's disease: utilization of transgenic Alzheimer's disease models in studies of amyloid beta clearance. Curr Transl Geriatr Exp Gerontol Rep 2012; 1: 11-20.
    • (2012) Curr Transl Geriatr Exp Gerontol Rep , vol.1 , pp. 11-20
    • Malm, T.1    Magga, J.2    Koistinaho, J.3
  • 41
    • 11844255779 scopus 로고    scopus 로고
    • Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to beta-amyloid deposition in APP/PS1 double transgenic Alzheimer mice
    • Malm TM, Koistinaho M, Parepalo M, Vatanen T, Ooka A, Karlsson S, et al. Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to beta-amyloid deposition in APP/PS1 double transgenic Alzheimer mice. Neurobiol Dis 2005; 18: 134-42.
    • (2005) Neurobiol Dis , vol.18 , pp. 134-142
    • Malm, T.M.1    Koistinaho, M.2    Parepalo, M.3    Vatanen, T.4    Ooka, A.5    Karlsson, S.6
  • 43
    • 0036949091 scopus 로고    scopus 로고
    • Local neuroinflammation and the progression of Alzheimer's disease
    • McGeer PL, McGeer EG. Local neuroinflammation and the progression of Alzheimer's disease. J Neurovirol 2002; 8: 529-38.
    • (2002) J Neurovirol , vol.8 , pp. 529-538
    • McGeer, P.L.1    McGeer, E.G.2
  • 44
    • 84887611153 scopus 로고    scopus 로고
    • Real-time in vivo imaging reveals the ability of monocytes to clear vascular amyloid beta
    • Michaud JP, Bellavance MA, Prefontaine P, Rivest S. Real-time in vivo imaging reveals the ability of monocytes to clear vascular amyloid beta. Cell Rep 2013; 5: 646-53.
    • (2013) Cell Rep , vol.5 , pp. 646-653
    • Michaud, J.P.1    Bellavance, M.A.2    Prefontaine, P.3    Rivest, S.4
  • 45
    • 84885356418 scopus 로고    scopus 로고
    • A deficiency in CCR2 + monocytes: The hidden side of Alzheimer's disease
    • Naert G, Rivest S. A deficiency in CCR2 + monocytes: the hidden side of Alzheimer's disease. J Mol Cell Biol 2013; 5: 284-93.
    • (2013) J Mol Cell Biol , vol.5 , pp. 284-293
    • Naert, G.1    Rivest, S.2
  • 46
    • 0030248270 scopus 로고    scopus 로고
    • Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor
    • Paresce DM, Ghosh RN, Maxfield FR. Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor. Neuron 1996; 17: 553-65.
    • (1996) Neuron , vol.17 , pp. 553-565
    • Paresce, D.M.1    Ghosh, R.N.2    Maxfield, F.R.3
  • 47
    • 84921322562 scopus 로고    scopus 로고
    • Phenotypic profile of alternative activation marker CD163 is different in Alzheimer's and Parkinson's disease
    • Pey P, Pearce RK, Kalaitzakis ME, Griffin WS, Gentleman SM. Phenotypic profile of alternative activation marker CD163 is different in Alzheimer's and Parkinson's disease. Acta Neuropathol Commun 2014; 2: 21.
    • (2014) Acta Neuropathol Commun , vol.2 , pp. 21
    • Pey, P.1    Pearce, R.K.2    Kalaitzakis, M.E.3    Griffin, W.S.4    Gentleman, S.M.5
  • 48
    • 84880525521 scopus 로고    scopus 로고
    • Increased in vivo amyloid-beta42 production, exchange, and loss in presenilin mutation carriers
    • Potter R, Patterson BW, Elbert DL, Ovod V, Kasten T, Sigurdson W, et al. Increased in vivo amyloid-beta42 production, exchange, and loss in presenilin mutation carriers. Sci Transl Med 2013; 5: 189ra77.
    • (2013) Sci Transl Med , vol.5
    • Potter, R.1    Patterson, B.W.2    Elbert, D.L.3    Ovod, V.4    Kasten, T.5    Sigurdson, W.6
  • 49
    • 80053233055 scopus 로고    scopus 로고
    • Heterogeneity of CNS myeloid cells and their roles in neurodegeneration
    • Prinz M, Priller J, Sisodia SS, Ransohoff RM. Heterogeneity of CNS myeloid cells and their roles in neurodegeneration. Nat Neurosci 2011; 14: 1227-35.
    • (2011) Nat Neurosci , vol.14 , pp. 1227-1235
    • Prinz, M.1    Priller, J.2    Sisodia, S.S.3    Ransohoff, R.M.4
  • 50
    • 0028989154 scopus 로고
    • Proliferation is a prerequisite for bacterial superantigen-induced T cell apoptosis in vivo
    • Renno T, Hahne M, MacDonald HR. Proliferation is a prerequisite for bacterial superantigen-induced T cell apoptosis in vivo. J Exp Med 1995; 181: 2283-7.
    • (1995) J Exp Med , vol.181 , pp. 2283-2287
    • Renno, T.1    Hahne, M.2    MacDonald, H.R.3
  • 51
    • 45949106077 scopus 로고    scopus 로고
    • Toll-like receptor 2 acts as a natural innate immune receptor to clear amyloid beta 1-42 and delay the cognitive decline in a mouse model of Alzheimer's disease
    • Richard KL, Filali M, Prefontaine P, Rivest S. Toll-like receptor 2 acts as a natural innate immune receptor to clear amyloid beta 1-42 and delay the cognitive decline in a mouse model of Alzheimer's disease. J Neurosci 2008; 28: 5784-93.
    • (2008) J Neurosci , vol.28 , pp. 5784-5793
    • Richard, K.L.1    Filali, M.2    Prefontaine, P.3    Rivest, S.4
  • 52
    • 78650768901 scopus 로고    scopus 로고
    • Screening renal artery angiography in hypertensive patients undergoing coronary angiography and 6-month follow-up after ad hoc percutaneous revascularization
    • Rimoldi SF, de Marchi SF, Windecker S, Meier B, Allemann Y. Screening renal artery angiography in hypertensive patients undergoing coronary angiography and 6-month follow-up after ad hoc percutaneous revascularization. J Hypertens 2010; 28: 842-7.
    • (2010) J Hypertens , vol.28 , pp. 842-847
    • Rimoldi, S.F.1    De Marchi, S.F.2    Windecker, S.3    Meier, B.4    Allemann, Y.5
  • 53
    • 0031969223 scopus 로고    scopus 로고
    • Alzheimer's disease as proteolytic disorders: Anabolism and catabolism of beta-amyloid
    • Saido TC. Alzheimer's disease as proteolytic disorders: anabolism and catabolism of beta-amyloid. Neurobiol Aging 1998; 19: S69-75.
    • (1998) Neurobiol Aging , vol.19 , pp. S69-S75
    • Saido, T.C.1
  • 54
    • 44549087765 scopus 로고    scopus 로고
    • Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior
    • Selkoe DJ. Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior. Behav Brain Res 2008; 192: 106-13.
    • (2008) Behav Brain Res , vol.192 , pp. 106-113
    • Selkoe, D.J.1
  • 55
    • 49149124343 scopus 로고    scopus 로고
    • Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
    • Shankar GM, Li S, Mehta TH, Garcia-Munoz A, Shepardson NE, Smith I, et al. Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. Nat Med 2008; 14: 837-42.
    • (2008) Nat Med , vol.14 , pp. 837-842
    • Shankar, G.M.1    Li, S.2    Mehta, T.H.3    Garcia-Munoz, A.4    Shepardson, N.E.5    Smith, I.6
  • 56
    • 68049143269 scopus 로고    scopus 로고
    • Infiltrating blood-derived macrophages are vital cells playing an anti-inflammatory role in recovery from spinal cord injury in mice
    • Shechter R, London A, Varol C, Raposo C, Cusimano M, Yovel G, et al. Infiltrating blood-derived macrophages are vital cells playing an anti-inflammatory role in recovery from spinal cord injury in mice. PLoS Med 2009; 6: e1000113.
    • (2009) PLoS Med , vol.6
    • Shechter, R.1    London, A.2    Varol, C.3    Raposo, C.4    Cusimano, M.5    Yovel, G.6
  • 57
    • 32344440522 scopus 로고    scopus 로고
    • Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease
    • Simard AR, Soulet D, Gowing G, Julien JP, Rivest S. Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease. Neuron 2006; 49: 489-502.
    • (2006) Neuron , vol.49 , pp. 489-502
    • Simard, A.R.1    Soulet, D.2    Gowing, G.3    Julien, J.P.4    Rivest, S.5
  • 58
    • 33846446438 scopus 로고    scopus 로고
    • Microglial transplantation increases amyloid-beta clearance in Alzheimer model rats
    • Takata K, Kitamura Y, Yanagisawa D, Morikawa S, Morita M, Inubushi T, et al. Microglial transplantation increases amyloid-beta clearance in Alzheimer model rats. FEBS Lett 2007; 581: 475-8.
    • (2007) FEBS Lett , vol.581 , pp. 475-478
    • Takata, K.1    Kitamura, Y.2    Yanagisawa, D.3    Morikawa, S.4    Morita, M.5    Inubushi, T.6
  • 59
    • 33846408655 scopus 로고    scopus 로고
    • Monocytes give rise to mucosal, but not splenic, conventional dendritic cells
    • Varol C, Landsman L, Fogg DK, Greenshtein L, Gildor B, Margalit R, et al. Monocytes give rise to mucosal, but not splenic, conventional dendritic cells. J Exp Med 2007; 204: 171-80.
    • (2007) J Exp Med , vol.204 , pp. 171-180
    • Varol, C.1    Landsman, L.2    Fogg, D.K.3    Greenshtein, L.4    Gildor, B.5    Margalit, R.6
  • 60
    • 34547699396 scopus 로고    scopus 로고
    • Type II monocytes modulate T cell-mediated central nervous system autoimmune disease
    • Weber MS, Prod'homme T, Youssef S, Dunn SE, Rundle CD, Lee L, et al. Type II monocytes modulate T cell-mediated central nervous system autoimmune disease. Nat Med 2007; 13: 935-43.
    • (2007) Nat Med , vol.13 , pp. 935-943
    • Weber, M.S.1    Prod'Homme, T.2    Youssef, S.3    Dunn, S.E.4    Rundle, C.D.5    Lee, L.6
  • 62
    • 33748471099 scopus 로고    scopus 로고
    • Inflammation in Alzheimer disease: Driving force, bystander or beneficial response?
    • Wyss-Coray T. Inflammation in Alzheimer disease: driving force, bystander or beneficial response? Nat Med 2006; 12: 1005-15.
    • (2006) Nat Med , vol.12 , pp. 1005-1015
    • Wyss-Coray, T.1
  • 63
    • 0034744296 scopus 로고    scopus 로고
    • TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice
    • Wyss-Coray T, Lin C, Yan F, Yu GQ, Rohde M, McConlogue L, et al. TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice. Nat Med 2001; 7: 612-8.
    • (2001) Nat Med , vol.7 , pp. 612-618
    • Wyss-Coray, T.1    Lin, C.2    Yan, F.3    Yu, G.Q.4    Rohde, M.5    McConlogue, L.6
  • 64
    • 0036685522 scopus 로고    scopus 로고
    • Inflammation in neurodegenerative disease - A double-edged sword
    • Wyss-Coray T, Mucke L. Inflammation in neurodegenerative disease-a double-edged sword. Neuron 2002; 35: 419-32.
    • (2002) Neuron , vol.35 , pp. 419-432
    • Wyss-Coray, T.1    Mucke, L.2
  • 65
    • 84870226700 scopus 로고    scopus 로고
    • PPARgamma/RXRalpha-induced and CD36-mediated microglial amyloid-beta phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice
    • Yamanaka M, Ishikawa T, Griep A, Axt D, Kummer MP, Heneka MT. PPARgamma/RXRalpha-induced and CD36-mediated microglial amyloid-beta phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice. J Neurosci 2012; 32: 17321-31.
    • (2012) J Neurosci , vol.32 , pp. 17321-17331
    • Yamanaka, M.1    Ishikawa, T.2    Griep, A.3    Axt, D.4    Kummer, M.P.5    Heneka, M.T.6
  • 66
    • 63849319352 scopus 로고    scopus 로고
    • Macrophage-mediated degradation of beta-amyloid via an apolipoprotein E isoform-dependent mechanism
    • Zhao L, Lin S, Bales KR, Gelfanova V, Koger D, Delong C, et al. Macrophage-mediated degradation of beta-amyloid via an apolipoprotein E isoform-dependent mechanism. J Neurosci 2009; 29: 3603-12.
    • (2009) J Neurosci , vol.29 , pp. 3603-3612
    • Zhao, L.1    Lin, S.2    Bales, K.R.3    Gelfanova, V.4    Koger, D.5    Delong, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.