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Volumn 49, Issue , 2015, Pages 280-292

The choroid plexus transcriptome reveals changes in type I and II interferon responses in a mouse model of Alzheimer's disease

Author keywords

Aging; Alzheimer's disease; Cerebrospinal fluid; Choroid plexus; Glial cells; Hippocampus; Interferons; Memory; Neuroinflammation; Transcriptome

Indexed keywords

ALPHA1 INTERFERON; AMYLOID BETA PROTEIN; BETA1 INTERFERON; GAMMA INTERFERON; INTERCELLULAR ADHESION MOLECULE 1; INTERFERON; INTERFERON REGULATORY FACTOR 7; TOLL LIKE RECEPTOR 9; TRANSCRIPTOME;

EID: 84940599385     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2015.06.008     Document Type: Article
Times cited : (66)

References (46)
  • 1
    • 0032211097 scopus 로고    scopus 로고
    • Transgenic expression of IFN-alpha in the central nervous system of mice protects against lethal neurotropic viral infection but induces inflammation and neurodegeneration
    • Akwa Y., Hassett D.E., Eloranta M.L., Sandberg K., Masliah E., Powell H., Whitton J.L., Bloom F.E., Campbell I.L. Transgenic expression of IFN-alpha in the central nervous system of mice protects against lethal neurotropic viral infection but induces inflammation and neurodegeneration. J. Immunol. 1998, 161:5016-5026.
    • (1998) J. Immunol. , vol.161 , pp. 5016-5026
    • Akwa, Y.1    Hassett, D.E.2    Eloranta, M.L.3    Sandberg, K.4    Masliah, E.5    Powell, H.6    Whitton, J.L.7    Bloom, F.E.8    Campbell, I.L.9
  • 3
    • 84904957734 scopus 로고    scopus 로고
    • Accelerated microglial pathology is associated with Abeta plaques in mouse models of Alzheimer's disease
    • Baron R., Babcock A.A., Nemirovsky A., Finsen B., Monsonego A. Accelerated microglial pathology is associated with Abeta plaques in mouse models of Alzheimer's disease. Aging Cell 2014, 13:584-595.
    • (2014) Aging Cell , vol.13 , pp. 584-595
    • Baron, R.1    Babcock, A.A.2    Nemirovsky, A.3    Finsen, B.4    Monsonego, A.5
  • 4
    • 84885063645 scopus 로고    scopus 로고
    • CNS-specific T cells shape brain function via the choroid plexus
    • Baruch K., Schwartz M. CNS-specific T cells shape brain function via the choroid plexus. Brain Behav. Immun. 2013, 34:11-16.
    • (2013) Brain Behav. Immun. , vol.34 , pp. 11-16
    • Baruch, K.1    Schwartz, M.2
  • 7
    • 84893969832 scopus 로고    scopus 로고
    • Neuronal and glial alterations, increased anxiety, and cognitive impairment before hippocampal amyloid deposition in PDAPP mice, model of Alzheimer's disease
    • Beauquis J., Vinuesa A., Pomilio C., Pavia P., Galvan V., Saravia F. Neuronal and glial alterations, increased anxiety, and cognitive impairment before hippocampal amyloid deposition in PDAPP mice, model of Alzheimer's disease. Hippocampus 2014, 24:257-269.
    • (2014) Hippocampus , vol.24 , pp. 257-269
    • Beauquis, J.1    Vinuesa, A.2    Pomilio, C.3    Pavia, P.4    Galvan, V.5    Saravia, F.6
  • 8
    • 0032621790 scopus 로고    scopus 로고
    • TNFalpha plus IFNgamma induce the production of Alzheimer beta-amyloid peptides and decrease the secretion of APPs
    • Blasko I., Marx F., Steiner E., Hartmann T., Grubeck-Loebenstein B. TNFalpha plus IFNgamma induce the production of Alzheimer beta-amyloid peptides and decrease the secretion of APPs. FASEB J. 1999, 13:63-68.
    • (1999) FASEB J. , vol.13 , pp. 63-68
    • Blasko, I.1    Marx, F.2    Steiner, E.3    Hartmann, T.4    Grubeck-Loebenstein, B.5
  • 9
    • 84874225589 scopus 로고    scopus 로고
    • IFN-gamma Production by amyloid beta-specific Th1 cells promotes microglial activation and increases plaque burden in a mouse model of Alzheimer's disease
    • Browne T.C., McQuillan K., McManus R.M., O'Reilly J.A., Mills K.H., Lynch M.A. IFN-gamma Production by amyloid beta-specific Th1 cells promotes microglial activation and increases plaque burden in a mouse model of Alzheimer's disease. J. Immunol. 2013, 190:2241-2251.
    • (2013) J. Immunol. , vol.190 , pp. 2241-2251
    • Browne, T.C.1    McQuillan, K.2    McManus, R.M.3    O'Reilly, J.A.4    Mills, K.H.5    Lynch, M.A.6
  • 10
  • 11
    • 28044466172 scopus 로고    scopus 로고
    • Choroid plexus megalin is involved in neuroprotection by serum insulin-like growth factor I
    • Carro E., Spuch C., Trejo J.L., Antequera D., Torres-Aleman I. Choroid plexus megalin is involved in neuroprotection by serum insulin-like growth factor I. J. Neurosci. 2005, 25:10884-10893.
    • (2005) J. Neurosci. , vol.25 , pp. 10884-10893
    • Carro, E.1    Spuch, C.2    Trejo, J.L.3    Antequera, D.4    Torres-Aleman, I.5
  • 12
    • 80054739524 scopus 로고    scopus 로고
    • Designing, performing, and interpreting a microarray-based gene expression study
    • Coppola G. Designing, performing, and interpreting a microarray-based gene expression study. Methods Mol. Biol. 2011, 793:417-439.
    • (2011) Methods Mol. Biol. , vol.793 , pp. 417-439
    • Coppola, G.1
  • 14
    • 84880811222 scopus 로고    scopus 로고
    • Toll-like receptor 3 activation modulates hippocampal network excitability, via glial production of interferon-beta
    • Costello D.A., Lynch M.A. Toll-like receptor 3 activation modulates hippocampal network excitability, via glial production of interferon-beta. Hippocampus 2013, 23:696-707.
    • (2013) Hippocampus , vol.23 , pp. 696-707
    • Costello, D.A.1    Lynch, M.A.2
  • 15
    • 84922727888 scopus 로고    scopus 로고
    • Age-dependent alterations of the hippocampal cell composition and proliferative potential in the hAbetaPPSwInd-J20 mouse
    • Fu Y., Rusznak Z., Kwok J.B., Kim W.S., Paxinos G. Age-dependent alterations of the hippocampal cell composition and proliferative potential in the hAbetaPPSwInd-J20 mouse. J. Alzheimers Dis. 2014, 41:1177-1192.
    • (2014) J. Alzheimers Dis. , vol.41 , pp. 1177-1192
    • Fu, Y.1    Rusznak, Z.2    Kwok, J.B.3    Kim, W.S.4    Paxinos, G.5
  • 16
    • 84874882726 scopus 로고    scopus 로고
    • Sustained interleukin-1beta overexpression exacerbates tau pathology despite reduced amyloid burden in an Alzheimer's mouse model
    • Ghosh S., Wu M.D., Shaftel S.S., Kyrkanides S., LaFerla F.M., Olschowka J.A., O'Banion M.K. Sustained interleukin-1beta overexpression exacerbates tau pathology despite reduced amyloid burden in an Alzheimer's mouse model. J. Neurosci. 2013, 33:5053-5064.
    • (2013) J. Neurosci. , vol.33 , pp. 5053-5064
    • Ghosh, S.1    Wu, M.D.2    Shaftel, S.S.3    Kyrkanides, S.4    LaFerla, F.M.5    Olschowka, J.A.6    O'Banion, M.K.7
  • 17
    • 0035943436 scopus 로고    scopus 로고
    • Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils
    • Gotz J., Chen F., van Dorpe J., Nitsch R.M. Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils. Science 2001, 293:1491-1495.
    • (2001) Science , vol.293 , pp. 1491-1495
    • Gotz, J.1    Chen, F.2    van Dorpe, J.3    Nitsch, R.M.4
  • 18
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
    • Hardy J., Selkoe D.J. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 2002, 297:353-356.
    • (2002) Science , vol.297 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 19
    • 84908317354 scopus 로고    scopus 로고
    • Sleep restriction impairs blood-brain barrier function
    • He J., Hsuchou H., He Y., Kastin A.J., Wang Y., Pan W. Sleep restriction impairs blood-brain barrier function. J. Neurosci. 2014, 34:14697-14706.
    • (2014) J. Neurosci. , vol.34 , pp. 14697-14706
    • He, J.1    Hsuchou, H.2    He, Y.3    Kastin, A.J.4    Wang, Y.5    Pan, W.6
  • 21
    • 84887057618 scopus 로고    scopus 로고
    • IFN-gamma-dependent activation of the brain's choroid plexus for CNS immune surveillance and repair
    • Kunis G., Baruch K., Rosenzweig N., Kertser A., Miller O., Berkutzki T., Schwartz M. IFN-gamma-dependent activation of the brain's choroid plexus for CNS immune surveillance and repair. Brain 2013, 136:3427-3440.
    • (2013) Brain , vol.136 , pp. 3427-3440
    • Kunis, G.1    Baruch, K.2    Rosenzweig, N.3    Kertser, A.4    Miller, O.5    Berkutzki, T.6    Schwartz, M.7
  • 23
    • 70349807619 scopus 로고    scopus 로고
    • Immune activation in brain aging and neurodegeneration: too much or too little?
    • Lucin K.M., Wyss-Coray T. Immune activation in brain aging and neurodegeneration: too much or too little?. Neuron 2009, 64:110-122.
    • (2009) Neuron , vol.64 , pp. 110-122
    • Lucin, K.M.1    Wyss-Coray, T.2
  • 26
    • 73649129558 scopus 로고    scopus 로고
    • Interferon-{gamma} differentially affects Alzheimer's disease pathologies and induces neurogenesis in triple transgenic-AD mice
    • Mastrangelo M.A., Sudol K.L., Narrow W.C., Bowers W.J. Interferon-{gamma} differentially affects Alzheimer's disease pathologies and induces neurogenesis in triple transgenic-AD mice. Am. J. Pathol. 2009, 175:2076-2088.
    • (2009) Am. J. Pathol. , vol.175 , pp. 2076-2088
    • Mastrangelo, M.A.1    Sudol, K.L.2    Narrow, W.C.3    Bowers, W.J.4
  • 27
    • 77955872434 scopus 로고
    • In search of power: a statistical power analysis of contemporary research in strategic management
    • Mazen A.M.M., Hemmasi M., Lewis M.F. In search of power: a statistical power analysis of contemporary research in strategic management. Acad. Manage. Proc. 1985, 1985:30-34.
    • (1985) Acad. Manage. Proc. , vol.1985 , pp. 30-34
    • Mazen, A.M.M.1    Hemmasi, M.2    Lewis, M.F.3
  • 28
    • 84868252916 scopus 로고    scopus 로고
    • Astrocytes: conductors of the Alzheimer disease neuroinflammatory symphony
    • Medeiros R., LaFerla F.M. Astrocytes: conductors of the Alzheimer disease neuroinflammatory symphony. Exp. Neurol. 2013, 239:133-138.
    • (2013) Exp. Neurol. , vol.239 , pp. 133-138
    • Medeiros, R.1    LaFerla, F.M.2
  • 30
    • 33645517069 scopus 로고    scopus 로고
    • Abeta-induced meningoencephalitis is IFN-gamma-dependent and is associated with T cell-dependent clearance of Abeta in a mouse model of Alzheimer's disease
    • Monsonego A., Imitola J., Petrovic S., Zota V., Nemirovsky A., Baron R., Fisher Y., Owens T., Weiner H.L. Abeta-induced meningoencephalitis is IFN-gamma-dependent and is associated with T cell-dependent clearance of Abeta in a mouse model of Alzheimer's disease. Proc. Natl. Acad. Sci. USA 2006, 103:5048-5053.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 5048-5053
    • Monsonego, A.1    Imitola, J.2    Petrovic, S.3    Zota, V.4    Nemirovsky, A.5    Baron, R.6    Fisher, Y.7    Owens, T.8    Weiner, H.L.9
  • 32
    • 77954132249 scopus 로고    scopus 로고
    • Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks
    • Palop J.J., Mucke L. Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks. Nat. Neurosci. 2010, 13:812-818.
    • (2010) Nat. Neurosci. , vol.13 , pp. 812-818
    • Palop, J.J.1    Mucke, L.2
  • 35
    • 33750731675 scopus 로고    scopus 로고
    • 100years and counting: prospects for defeating Alzheimer's disease
    • Roberson E.D., Mucke L. 100years and counting: prospects for defeating Alzheimer's disease. Science 2006, 314:781-784.
    • (2006) Science , vol.314 , pp. 781-784
    • Roberson, E.D.1    Mucke, L.2
  • 39
    • 84861497648 scopus 로고    scopus 로고
    • A possible role for CSF turnover and choroid plexus in the pathogenesis of late onset Alzheimer's disease
    • Serot J.M., Zmudka J., Jouanny P. A possible role for CSF turnover and choroid plexus in the pathogenesis of late onset Alzheimer's disease. J. Alzheimers Dis. 2012, 30:17-26.
    • (2012) J. Alzheimers Dis. , vol.30 , pp. 17-26
    • Serot, J.M.1    Zmudka, J.2    Jouanny, P.3
  • 41
    • 84893734805 scopus 로고    scopus 로고
    • Type-1 interferon signaling mediates neuro-inflammatory events in models of Alzheimer's disease
    • Taylor J.M., Minter M.R., Newman A.G., Zhang M., Adlard P.A., Crack P.J. Type-1 interferon signaling mediates neuro-inflammatory events in models of Alzheimer's disease. Neurobiol. Aging 2014, 35:1012-1023.
    • (2014) Neurobiol. Aging , vol.35 , pp. 1012-1023
    • Taylor, J.M.1    Minter, M.R.2    Newman, A.G.3    Zhang, M.4    Adlard, P.A.5    Crack, P.J.6
  • 44
    • 33748471099 scopus 로고    scopus 로고
    • Inflammation in Alzheimer disease: driving force, bystander or beneficial response?
    • Wyss-Coray T. Inflammation in Alzheimer disease: driving force, bystander or beneficial response?. Nat. Med. 2006, 12:1005-1015.
    • (2006) Nat. Med. , vol.12 , pp. 1005-1015
    • Wyss-Coray, T.1
  • 45
    • 77958504804 scopus 로고    scopus 로고
    • Clocks not winding down: unravelling circadian networks
    • Zhang E.E., Kay S.A. Clocks not winding down: unravelling circadian networks. Nat. Rev. Mol. Cell Biol. 2010, 11:764-776.
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 764-776
    • Zhang, E.E.1    Kay, S.A.2
  • 46
    • 38149090292 scopus 로고    scopus 로고
    • The blood-brain barrier in health and chronic neurodegenerative disorders
    • Zlokovic B.V. The blood-brain barrier in health and chronic neurodegenerative disorders. Neuron 2008, 57:178-201.
    • (2008) Neuron , vol.57 , pp. 178-201
    • Zlokovic, B.V.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.