Selective chemokine mRNA accumulation in the rat spinal cord after contusion injury

Journal of Neuroscience Research

Volumn 53, Issue 3, 1998, Pages 368-376

  McTigue, Dana M ^a   Tani, Marie ^b   Krivacic, Kimberly ^b   Chernosky, Ann ^b   Kelner, Gregory S ^c   Maciejewski, Dominique ^c   Maki, Richard ^c   Ransohoff, Richard M ^b   Stokes, Bradford T ^a  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c NEUROCRINE BIOSCIENCES INC   (United States)

Author keywords

Cytokine; Inflammation; Spinal cord injury; Trauma

Indexed keywords

MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTUSION; FEMALE; INFLAMMATORY CELL; LEUKOCYTE MIGRATION; MYELITIS; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD INJURY;

ANIMALS; ANTIGEN PRESENTATION; CHEMOKINE CCL2; CHEMOKINES, CC; CHEMOKINES, CXC; CHEMOTACTIC FACTORS; CONTUSIONS; FEMALE; GENE EXPRESSION; GROWTH INHIBITORS; GROWTH SUBSTANCES; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MACROPHAGE INFLAMMATORY PROTEINS; MONOCYTE CHEMOATTRACTANT PROTEINS; POLYMERASE CHAIN REACTION; RANTES; RATS; RATS, INBRED LEW; RECEPTORS, CHEMOKINE; RNA, MESSENGER; SPINAL CORD INJURIES; T-LYMPHOCYTES; TIME FACTORS;

EID: 0032146758     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19980801)53:3<368::AID-JNR11>3.0.CO;2-1     Document Type: Article

References (67)

1. Adams DH, Lloyd AR (1997): Chemokines: leucocyte recruitment and activation cytokines. Lancet 349:490-495.
2. Anderson TE, Stokes BT (1992): Experimental models for spinal cord injury research: Physical and physiological considerations. J Neurotrauma 9:S135-S142.
3. Assoian RK, Fleurdelys BE, Stevenson HC, Miller PJ, Madtes DK, Raines EW, Ross R, Sporn MB (1987): Expression and secretion of type β transforming growth factor by activated human macrophages. Proc Natl Acad Sci 84:6020-6024.
4. Baggiolini M, Dewald B, Moser B (1994): Interleukin-8 and related chemotactive cytokines - CXC and CC chemokines. Adv Immunol 55:97-179.
5. Bartholdi D, Schwab ME (1997): Expression of pro-inflammatory cytokine and chemokine mRNA upon experimental spinal cord injury in mouse: An in situ hybridization study. Eur J Neurosci 9:1422-1438.
6. Basso DM, Beattie MS, Bresnahan JC (1996): A sensitive and reliable locomotor rating scale for open field testing in rats. J Neurotrauma 12:1-21.
7. Beggs JL, Waggener JD (1976): Transendothelial vesicular transport of protein following compression injury to the spinal cord. Lab Invest 34:428-439.
8. Bell MD, Taub DD, Kunkel SJ, Strieter RM, Foley R, Gauldie J, Perry VH (1996): Recombinant human adenovirus with rat MIP-2 gene insertion causes prolonged PMN recruitment to the murine brain. Eur J Neurosci 8:1803-1811.
9. Berman JW, Guida MP, Warren J, Amat J, Brosnan CF (1996): Localization of monocyte chemoattractant peptide-1 expression in the central nervous system in experimental autoimmune encephalomyelitis and trauma in the rat. J Immunol 156:3017-3023.
10. Blight AR (1985): Delayed demyelination and macrophage invasion: A candidate for secondary cell damage in spinal cord injury. Central Nerv Sys Trauma 2:299-315.
11. Blight AR (1994): Effects of silica on the outcome from experimental spinal cord injury: Implication of macrophages in secondary tissue damage. Neuroscience 60:263-273.
12. Carr MW, Roth SJ, Luther E, Rose SS, Springer TA (1994): Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant. Proc Natl Acad Sci 91:3652-3656.
13. Crowe MJ, Bresnahan JC, Shuman SL, Masters JN, Beattie MS (1997): Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys. Nature Med 3:73-76.
14. Dusart I, Schwab ME (1994): Secondary cell death and the inflammatory reaction after dorsal hemisection of the rat spinal cord. Eur J Neurosci 6:712-724.
15. Elkabes S, DiCicco-Bloom EM, Black IB (1996): Brain microglia/ macrophages express neurotrophins that selectively regulate microglial proliferation and function. J Neurosci 16:2508-2521.
16. Farber JM (1997): Mig and IP-10: CXC chemokines that target lymphocytes. J Leukocyte Biol 61:246-257.
17. Fuentes ME, Durham SK, Swerdel MR, Lewin AC, Barton DS, Megill JR, Bravo R, Lira SA (1995): Controlled recruitment of monocytes and macrophages to specific organs through transgenic expression of monocyte chemoattractant protein-1. J Immunol 155:5796-5776.
18. Glabinski AR, Tani M, Aras S, Stoler M, Tuohy V, Ransohoff R (1995): Regulation and function of central nervous system chemokines. Int J Dev Neurosci 13:153-165.
19. Glabinski AR, Balasingam, V, Tani M, Kunkel SL, Strieter RM, Yong VW, Ransohoff RM (1996a): Chemokine monocyte chemoattractant protein-1 is expressed by astrocytes after mechanical injury to the brain. J Immunol 156:4363-4368.
20. Glabinski A, Tani M, Tuohy VK, Tuthill RJ, Ransohoff R (1996b): Central nervous system chemokine mRNA accumulation follows leukocyte entry at the onset of murine acute experimental autoimmune encephalomyelitis. Brain Behav Immun 9:315-330.
21. Glabinski AR, Tani M, Strieter RM, Tuohy VK, Ransohoff RM (1997): Synchronous synthesis of α-and β-chemokines by cells of diverse lineage in the central nervous system of mice with relapses of chronic experimental autoimmune encephalomyelitis. Am J Pathol 150:617-630.
22. Gourmala NG, Buttini M, Limonta S, Sauter A, Boddeke HW (1997): Differential and time-dependent expression of monocyte chemoattractant protein-1 mRNA by astrocytes and macrophages in rat brain: effects of ischemia and peripheral lipopolysaccharide administration. J Neuroimmunol 74:35-44.
23. Griffiths IR, McCulloch M, Crawford RA (1978): Ultrastructural appearances of the spinal microvasculature between 12 hours and 5 days after impact injury. Acta Neuropathol 43:205-211.
24. Giulian D, Chen J, Ingeman JE, George JK, Noponen M (1989): The role of mononuclear phagocytes in wound healing after traumatic injury to adult mammalian brain. J Neurosci 9:4416-4429.
25. Giulian D, Li J, Leara B, Keenen C (1994): Phagocytic microglia release cytokines and cytotoxins that regulate the survival of astrocytes and neurons in culture. Neurochem Int 25:227-233.
26. Guth L, Zhang Z, Roberts E (1994): Key role for pregnenolone in combination therapy that promotes recovery after spinal cord injury. Proc Natl Acad Sci 91:12308-12312.
27. Hayashi M, Luo Y, Laning J, Strieter RM, Dorf ME (1995): Production and function of monocyte chemoattractant protein-1 and other β-chemokines in murine glial cells. J Neuroimmunol 60:143-150.
28. Henson PM, Henson JE, Fittschen C, Kimani G, Bratton DL, Riches DWH (1998): Phagocytic cells: Degranulation and secretion. In Gallin JI, Goldstein IM, Snyderman R (eds): "Inflammation. Basic Principles and Clinical Correlates." New York: Raven Press, Ltd., pp 363-390.
29. Horner PJ, Popovich PG, Reier PJ, Stokes BT (1994): Fetal spinal transplant vascularity: Metabolic and immunologic mechanisms. In Marwah J, Teitelbaum H, Prasad KN (eds): "Neural Transplantation, CNS Neuronal Injury, and Regeneration." Boca Raton: CRC Press Inc., pp 119-140.
30. Hurwitz AA, Lyman WD, Berman JW (1995): Tumor necrosis factor α and transforming growth factor βupregulate astrocyte expression of monocyte chemoattractant protein-1. J Neuroimmunol 57:193-198.
31. Kelvin DJ, Michiel DF, Johnston JA, Lloyd AR, Sprenger H, Oppenheim JJ, Wang J-M (1993): Chemokines and serpentines: The molecular biology of chemokine receptors. J Leukocyte Biol 54:604-612.
32. Kiefer R, Streit WJ, Toyka KV, Kreutzberg GW, Hartung H-P (1995): Transforming growth factor-β1: A lesion-associated cytokine of the nervous system. Int J Dev Neurosci 13:331-339.
33. Kim JS, Gautam SC, Chopp M, Zaloga C, Jones ML, Ward PA, Welch KMA (1995): Expression of monocyte chemoattractant protein-1 and macrophage inflammatory protein-1 after focal cerebral ischemia in the rat. J Neuroimmunol 56:127-143.
34. Lehrmann E, Kiefer R, Finsen B, Diemer NH, Zimmer J, Hartung H-P (1995): Cytokines in cerebral ischemia: Expression of transforming growth factor beta-1 (TGF-β1) mRNA in the postischemic adult rat hippocampus. Exp Neurol 131:114-123.
35. Luster AD, Unkeless JC, Ravetch JV (1985): γ-Interferon transcriptionally regulates an early-response gene containing homology to platelet proteins. Nature 315:672-676.
36. Majumder S, Zhou Z-HL, Ransohoff R (1996): Transcriptional regulation of chemokine gene expression in astrocytes. J Neurosci Res 45:758-769.
37. Means ED, Anderson DK (1983): Neuronophagia by leukocytes in experimental spinal cord injury. J Neuropath Exp Neurol 42:707-719.
38. Merrill JE, Ignarro LJ, Sherman MP, Melinek J, Lane TE (1993): Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide. J Immunol 151:2132-2141.
39. Middleton J, Neil S, Wintle J, dark-Lewis I, Moore H, Lam C, Auer M, Hub E, Rot A (1997): Transcytosis and surface presentation of IL-8 by venular endothelial cells. Cell 91: 385-395.
40. Murphy P (1996): Chemokine receptors: structure, function and role in microbial pathogenesis. Cytokine Growth Factor Rev 7:47-65.
41. Ping D, Jones PL, Boss JM (1996): TNF regulates the in vivo occupancy of both distal and proximal regulatory regions of the MCP-1/JE gene. Immunity 4:455-469.
42. Popovich PG, Whitacre CC, Stokes BT (1996): Concept of autoimmunity following spinal cord injury: Possible roles for T lymphocytes in the traumatized central nervous system. J Neurosci Res 45:349-363.
43. Popovich PG, Huitinga I, van Rooijen N, Stokes BT (1997a): Selective depletion of peripheral macrophages attenuates myelin loss and improves hindlimb function in spinal injured rats. J Neurotrauma 14:790. (Abstract)
44. Popovich PG, Wei P, Stokes BT (1997b): Cellular inflammatory response after spinal cord injury in Sprague-Dawley and Lewis rats. J Comp Neurol 377:443-464.
45. Ransohoff RM (1997): Chemokines in neurological disease models: correlation between chemokine expression patterns and inflammatory pathology. J Leukocyte Biol 62:645-652.
46. Ransohoff RM, Tani M (1998): Do chemokines mediate leukocyte recruitment in post-traumatic CNS inflammation? Trends Neurosci 21:154-159.
47. Ransohoff RM, Hamilton TA, Tani M, Stoler MH, Shick HE, Major JA, Estes ML, Thomas DM, Tuohy VK (1993): Astrocyte expression of mRNA encoding cytokines IP-10 and JE/MCP-1 in experimental autoimmune encephalomyelitis. FASEB J 7:592-600.
48. Ransohoff RM, Glabinski AR, Tani M (1996): Chemokines in immune-mediated inflammation of the central nervous system. Cytokine Growth Factor Rev 7:35-46.
49. Ransohoff RM, Tani M, Glabinski AR, Chernosky A, Krivacic K, Peterson J, Chien H-F, Trapp B. (1997): Chemokines and chemokine receptors in model neurological pathologies: molecular and immunocytochemical approaches. Methods Enzymol 287:319-348.
50. Rollins B (1997): Chemokines. Blood 90:909-928.
51. Schall TJ, Bacon KB (1994): Chemokines, leukocyte trafficking, and inflammation. Curr Opin Immunol 6:865-874.
52. Schwab ME (1990): Myelin-associated inhibitors of neunte growth and regeneration in the CNS. Trends Neurosci 13:452-456.
53. Schwab ME, Bartholdi D (1996): Degeneration and regeneration of axons in the lesioned spinal cord. Physiol Rev 76:319-370.
54. Shuman SL, Bresnahan JC, Beattie MS (1997): Apoptosis of microglia and oligodendrocytes after spinal cord injury in rats. J Neurosci Res 50:798-808.
55. Smith JB, Herschman HR (1995): Glucocorticoid-attenuated response genes encode intercellular mediators including a new C-X-C chemokine. J Biol Chem 270:16756-1675.
56. Smith JB, Herschman HR (1997): Identification of inflammatory mediators by screening for glucocorticoid-attenuated response genes. Methods Enzymol 287:250-65.
57. Stokes BT, Noyes DH, Behrmann DL (1992): An electromechanical spinal injury technique with dynamic sensitivity. J Neurotrauma 9:187-195.
58. Stokes BT, Horner PJ, Akino M (1995): Spinal cord injury modeling and functional assessment. In Ohnishi ST, Ohnishi T (eds): "Central Nervous System Trauma: Research Techniques." New York: CRC Press, pp 281-295.
59. Streit WJ, Semple-Rowland SL, Hurley SD, Miller RC, Popovich PG, Stokes BT (1998): Cytokine mRNA transcription profiles in contused spinal cord and axotomized facial nucleus suggest a pro-regenerative role for inflammation and gliosis. Exp Neurol (in press).
60. Sun D, Hu X, Liu X, Whitaker JN, Walker WS (1997): Expression of chemokine genes in rat glial cells: the effect of myelin basic protein-reactive encephalitogenic T cells. J Neurosci Res 48:192-200.
61. Tani M, Fuentes ME, Peterson JW, Trapp BD, Durham SK, Loy JK, Bravo R, Ransohoff RM, Lira SA (1996): Neutrophil infiltration, glial reaction and neurological disease in transgenic mice expressing the chemokine N51/KC in oligodendrocytes. J Clin Invest 98:529-539.
62. Taub DD, Lloyd AR, Conlon K, Wang JM, Ortaldo JR, Harada A, Matsushima K, Kelvin DJ, Oppenheim JJ (1993): Recombinant human interferon-inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T cell adhesion to endothelial cells. J Exp Med 177:1809-1814.
63. Yakovlev AG, Faden AI (1994): Sequential expression of c-fos protooncogene, TNF-alpha, and dynorphin genes in spinal cord following experimental traumatic injury. Mol Chem Neuropath 23:179-190.
64. Wang CX, Olschowka JA, Wrathall JR (1997): Increase of interleukin-1β mRNA and protein in the spinal cord following experimental traumatic injury in the rat. Brain Res 759:190-196.
65. Weiss SJ (1989): Tissue destruction by neutrophils. N E J Med 320:365-376.
66. Zhang Z, Krebs CJ, Guth L (1997): Experimental analysis of progressive necrosis after spinal cord trauma in the rat: Etiological role of the inflammatory response. Exp Neurol 143:141-152.
67. Zhou ZH, Chaturvedi P, Han Y-L, Aras S, Li Y-S, Kolattukudy PE, Ping D, Boss JM, Ransohoff RM (1998): Interferon-γ induction of the human monocyte chemoattractant (hMCP)-1 gene in astrocytoma cells: functional interaction between a gamma activated site (GAS) and GC-rich element. J Immunol 160:3908-3917.