-
1
-
-
0030970058
-
Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis
-
Benveniste E.N. Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis. J. Mol. Med. 1997, 75:165-173.
-
(1997)
J. Mol. Med.
, vol.75
, pp. 165-173
-
-
Benveniste, E.N.1
-
2
-
-
68149169760
-
Inhibition of ERK MAPK suppresses IL-23- and IL-1-driven IL-17 production and attenuates autoimmune disease
-
Brereton C.F., Sutton C.E., Lalor S.J., Lavelle E.C., Mills K.H. Inhibition of ERK MAPK suppresses IL-23- and IL-1-driven IL-17 production and attenuates autoimmune disease. J. Immunol. 2009, 183:1715-1723.
-
(2009)
J. Immunol.
, vol.183
, pp. 1715-1723
-
-
Brereton, C.F.1
Sutton, C.E.2
Lalor, S.J.3
Lavelle, E.C.4
Mills, K.H.5
-
3
-
-
0028941871
-
The adhesion molecule and cytokine profile of multiple sclerosis lesions
-
Cannella B., Raine C.S. The adhesion molecule and cytokine profile of multiple sclerosis lesions. Ann. Neurol. 1995, 37:424-435.
-
(1995)
Ann. Neurol.
, vol.37
, pp. 424-435
-
-
Cannella, B.1
Raine, C.S.2
-
5
-
-
0031985336
-
Mature microglia resemble immature antigen-presenting cells
-
Carson M.J., Reilly C.R., Sutcliffe J.G., Lo D. Mature microglia resemble immature antigen-presenting cells. Glia 1998, 22:72-85.
-
(1998)
Glia
, vol.22
, pp. 72-85
-
-
Carson, M.J.1
Reilly, C.R.2
Sutcliffe, J.G.3
Lo, D.4
-
6
-
-
33748743268
-
CNS immune privilege: hiding in plain sight
-
Carson M.J., Doose J.M., Melchior B., Schmid C.D., Ploix C.C. CNS immune privilege: hiding in plain sight. Immunol. Rev. 2006, 213:48-65.
-
(2006)
Immunol. Rev.
, vol.213
, pp. 48-65
-
-
Carson, M.J.1
Doose, J.M.2
Melchior, B.3
Schmid, C.D.4
Ploix, C.C.5
-
7
-
-
25444464602
-
Myelin basic protein-primed T cells of female but not male mice induce nitric-oxide synthase and proinflammatory cytokines in microglia: implications for gender bias in multiple sclerosis
-
Dasgupta S., Jana M., Liu X., Pahan K. Myelin basic protein-primed T cells of female but not male mice induce nitric-oxide synthase and proinflammatory cytokines in microglia: implications for gender bias in multiple sclerosis. J. Biol. Chem. 2005, 280:32609-32617.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 32609-32617
-
-
Dasgupta, S.1
Jana, M.2
Liu, X.3
Pahan, K.4
-
8
-
-
70449519444
-
A novel anti-inflammatory role of NCAM-derived mimetic peptide FGL
-
Downer E.J., Cowley T.R., Lyons A., Mills K.H., Berezin V., Bock E., Lynch M.A. A novel anti-inflammatory role of NCAM-derived mimetic peptide FGL. Neurobiol. Ageing 2010, 31:118-128.
-
(2010)
Neurobiol. Ageing
, vol.31
, pp. 118-128
-
-
Downer, E.J.1
Cowley, T.R.2
Lyons, A.3
Mills, K.H.4
Berezin, V.5
Bock, E.6
Lynch, M.A.7
-
9
-
-
0031852288
-
IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis
-
Eugster H.P., Frei K., Kopf M., Lassmann H., Fontana A. IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis. Eur. J. Immunol. 1998, 28:2178-2187.
-
(1998)
Eur. J. Immunol.
, vol.28
, pp. 2178-2187
-
-
Eugster, H.P.1
Frei, K.2
Kopf, M.3
Lassmann, H.4
Fontana, A.5
-
10
-
-
7244251521
-
Reversible demyelination, blood-brain barrier breakdown, and pronounced neutrophil recruitment induced by chronic IL-1 expression in the brain
-
Ferrari C.C., Depino A.M., Prada F., Muraro N., Campbell S., Podhajcer O., Perry V.H., Anthony D.C., Pitossi F.J. Reversible demyelination, blood-brain barrier breakdown, and pronounced neutrophil recruitment induced by chronic IL-1 expression in the brain. Am. J. Pathol. 2004, 165:1827-1837.
-
(2004)
Am. J. Pathol.
, vol.165
, pp. 1827-1837
-
-
Ferrari, C.C.1
Depino, A.M.2
Prada, F.3
Muraro, N.4
Campbell, S.5
Podhajcer, O.6
Perry, V.H.7
Anthony, D.C.8
Pitossi, F.J.9
-
11
-
-
0035865406
-
Brain dendritic cells and macrophages/microglia in central nervous system inflammation
-
Fischer H.G., Reichmann G. Brain dendritic cells and macrophages/microglia in central nervous system inflammation. J. Immunol. 2001, 166:2717-2726.
-
(2001)
J. Immunol.
, vol.166
, pp. 2717-2726
-
-
Fischer, H.G.1
Reichmann, G.2
-
12
-
-
27544490377
-
+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat. Immunol. 2005, 6:1123-1132.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
Turner, H.4
Murphy, T.L.5
Murphy, K.M.6
Weaver, C.T.7
-
13
-
-
34948909646
-
Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation
-
Kebir H., Kreymborg K., Ifergan I., Dodelet-Devillers A., Cayrol R., Bernard M., Giuliani F., Arbour N., Becher B., Prat A. Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation. Nat. Med. 2007, 13:1173-1175.
-
(2007)
Nat. Med.
, vol.13
, pp. 1173-1175
-
-
Kebir, H.1
Kreymborg, K.2
Ifergan, I.3
Dodelet-Devillers, A.4
Cayrol, R.5
Bernard, M.6
Giuliani, F.7
Arbour, N.8
Becher, B.9
Prat, A.10
-
14
-
-
46949104323
-
IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition
-
Kroenke M.A., Carlson T.J., Andjelkovic A.V., Segal B.M. IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition. J. Exp. Med. 2008, 205:1535-1541.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1535-1541
-
-
Kroenke, M.A.1
Carlson, T.J.2
Andjelkovic, A.V.3
Segal, B.M.4
-
15
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
Langrish C.L., Chen Y., Blumenschein W.M., Mattson J., Basham B., Sedgwick J.D., McClanahan T., Kastelein R.A., Cua D.J. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J. Exp. Med. 2005, 201:233-240.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
Mattson, J.4
Basham, B.5
Sedgwick, J.D.6
McClanahan, T.7
Kastelein, R.A.8
Cua, D.J.9
-
16
-
-
68949119874
-
IL-1R signaling within the central nervous system regulates CXCL12 expression at the blood-brain barrier and disease severity during experimental autoimmune encephalomyelitis
-
McCandless E.E., Budde M., Lees J.R., Dorsey D., Lyng E., Klein R.S. IL-1R signaling within the central nervous system regulates CXCL12 expression at the blood-brain barrier and disease severity during experimental autoimmune encephalomyelitis. J. Immunol. 2009, 183:613-620.
-
(2009)
J. Immunol.
, vol.183
, pp. 613-620
-
-
McCandless, E.E.1
Budde, M.2
Lees, J.R.3
Dorsey, D.4
Lyng, E.5
Klein, R.S.6
-
17
-
-
34249049841
-
Antigen presentation in the CNS by myeloid dendritic cells drives progression of relapsing experimental autoimmune encephalomyelitis
-
Miller S.D., McMahon E.J., Schreiner B., Bailey S.L. Antigen presentation in the CNS by myeloid dendritic cells drives progression of relapsing experimental autoimmune encephalomyelitis. Ann. NY Acad. Sci. 2007, 1103:179-191.
-
(2007)
Ann. NY Acad. Sci.
, vol.1103
, pp. 179-191
-
-
Miller, S.D.1
McMahon, E.J.2
Schreiner, B.3
Bailey, S.L.4
-
18
-
-
0041344592
-
Activation of the c-Jun N-terminal kinase signaling cascade mediates the effect of amyloid-beta on long term potentiation and cell death in hippocampus: a role for interleukin-1beta?
-
Minogue A.M., Schmid A.W., Fogarty M.P., Moore A.C., Campbell V.A., Herron C.E., Lynch M.A. Activation of the c-Jun N-terminal kinase signaling cascade mediates the effect of amyloid-beta on long term potentiation and cell death in hippocampus: a role for interleukin-1beta?. J. Biol. Chem. 2003, 278:27971-27980.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 27971-27980
-
-
Minogue, A.M.1
Schmid, A.W.2
Fogarty, M.P.3
Moore, A.C.4
Campbell, V.A.5
Herron, C.E.6
Lynch, M.A.7
-
19
-
-
56149125346
-
Cutting edge: Th1 cells facilitate the entry of Th17 cells to the central nervous system during experimental autoimmune encephalomyelitis
-
O'Connor R.A., Prendergast C.T., Sabatos C.A., Lau C.W., Leech M.D., Wraith D.C., Anderton S.M. Cutting edge: Th1 cells facilitate the entry of Th17 cells to the central nervous system during experimental autoimmune encephalomyelitis. J. Immunol. 2008, 181:3750-3754.
-
(2008)
J. Immunol.
, vol.181
, pp. 3750-3754
-
-
O'Connor, R.A.1
Prendergast, C.T.2
Sabatos, C.A.3
Lau, C.W.4
Leech, M.D.5
Wraith, D.C.6
Anderton, S.M.7
-
20
-
-
0034952985
-
Metallothionein treatment reduces proinflammatory cytokines IL-6 and TNF-alpha and apoptotic cell death during experimental autoimmune encephalomyelitis (EAE)
-
Penkowa M., Hidalgo J. Metallothionein treatment reduces proinflammatory cytokines IL-6 and TNF-alpha and apoptotic cell death during experimental autoimmune encephalomyelitis (EAE). Exp. Neurol. 2001, 170:1-14.
-
(2001)
Exp. Neurol.
, vol.170
, pp. 1-14
-
-
Penkowa, M.1
Hidalgo, J.2
-
21
-
-
68149148572
-
Site-specific production of IL-6 in the central nervous system retargets and enhances the inflammatory response in experimental autoimmune encephalomyelitis
-
Quintana A., Muller M., Frausto R.F., Ramos R., Getts D.R., Sanz E., Hofer M.J., Krauthausen M., King N.J., Hidalgo J., Campbell I.L. Site-specific production of IL-6 in the central nervous system retargets and enhances the inflammatory response in experimental autoimmune encephalomyelitis. J. Immunol. 2009, 183:2079-2088.
-
(2009)
J. Immunol.
, vol.183
, pp. 2079-2088
-
-
Quintana, A.1
Muller, M.2
Frausto, R.F.3
Ramos, R.4
Getts, D.R.5
Sanz, E.6
Hofer, M.J.7
Krauthausen, M.8
King, N.J.9
Hidalgo, J.10
Campbell, I.L.11
-
22
-
-
0033996188
-
Tumor necrosis factor: a master-regulator of leukocyte movement
-
Sedgwick J.D., Riminton D.S., Cyster J.G., Korner H. Tumor necrosis factor: a master-regulator of leukocyte movement. Immunol. Today 2000, 21:110-113.
-
(2000)
Immunol. Today
, vol.21
, pp. 110-113
-
-
Sedgwick, J.D.1
Riminton, D.S.2
Cyster, J.G.3
Korner, H.4
-
23
-
-
0033764672
-
Tumour necrosis factor and anti-tumour necrosis factor approach to inflammatory demyelinating diseases of the central nervous system
-
Selmaj K.W. Tumour necrosis factor and anti-tumour necrosis factor approach to inflammatory demyelinating diseases of the central nervous system. Ann. Rheum. Dis. 2000, 59(Suppl 1):i94-102.
-
(2000)
Ann. Rheum. Dis.
, vol.59
, Issue.SUPPL 1
-
-
Selmaj, K.W.1
-
24
-
-
0030240326
-
The central nervous system as an immunocompetent organ: role of glial cells in antigen presentation
-
Shrikant P., Benveniste E.N. The central nervous system as an immunocompetent organ: role of glial cells in antigen presentation. J. Immunol. 1996, 157:1819-1822.
-
(1996)
J. Immunol.
, vol.157
, pp. 1819-1822
-
-
Shrikant, P.1
Benveniste, E.N.2
-
25
-
-
6944234040
-
Bone marrow stem cells have the ability to populate the entire central nervous system into fully differentiated parenchymal microglia
-
Simard A.R., Rivest S. Bone marrow stem cells have the ability to populate the entire central nervous system into fully differentiated parenchymal microglia. FASEB J. 2004, 18:998-1000.
-
(2004)
FASEB J.
, vol.18
, pp. 998-1000
-
-
Simard, A.R.1
Rivest, S.2
-
26
-
-
40449089827
-
Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells
-
Stromnes I.M., Cerretti L.M., Liggitt D., Harris R.A., Goverman J.M. Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells. Nat. Med. 2008, 14:337-342.
-
(2008)
Nat. Med.
, vol.14
, pp. 337-342
-
-
Stromnes, I.M.1
Cerretti, L.M.2
Liggitt, D.3
Harris, R.A.4
Goverman, J.M.5
-
27
-
-
33846783031
-
An interferon-gamma-producing Th1 subset is the major source of IL-17 in experimental autoimmune encephalitis
-
Suryani S., Sutton I. An interferon-gamma-producing Th1 subset is the major source of IL-17 in experimental autoimmune encephalitis. J. Neuroimmunol. 2007, 183:96-103.
-
(2007)
J. Neuroimmunol.
, vol.183
, pp. 96-103
-
-
Suryani, S.1
Sutton, I.2
-
28
-
-
33745873727
-
A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis
-
Sutton C., Brereton C., Keogh B., Mills K.H., Lavelle E.C. A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis. J. Exp. Med. 2006, 203:1685-1691.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 1685-1691
-
-
Sutton, C.1
Brereton, C.2
Keogh, B.3
Mills, K.H.4
Lavelle, E.C.5
-
29
-
-
68649088121
-
Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity
-
Sutton C.E., Lalor S.J., Sweeney C.M., Brereton C.F., Lavelle E.C., Mills K.H. Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity. Immunity 2009, 31:331-341.
-
(2009)
Immunity
, vol.31
, pp. 331-341
-
-
Sutton, C.E.1
Lalor, S.J.2
Sweeney, C.M.3
Brereton, C.F.4
Lavelle, E.C.5
Mills, K.H.6
-
30
-
-
32244442562
-
TGF beta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
-
Veldhoen M., Hocking R.J., Atkins C.J., Locksley R.M., Stockinger B. TGF beta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 2006, 24:179-189.
-
(2006)
Immunity
, vol.24
, pp. 179-189
-
-
Veldhoen, M.1
Hocking, R.J.2
Atkins, C.J.3
Locksley, R.M.4
Stockinger, B.5
|