-
1
-
-
33644607018
-
Multiple sclerosis-the plaque and its pathogenesis
-
Frohman EM, Racke MK, Raine CS. Multiple sclerosis-the plaque and its pathogenesis. N Engl J Med 2006 354 : 942 955.
-
(2006)
N Engl J Med
, vol.354
, pp. 942-955
-
-
Frohman, E.M.1
Racke, M.K.2
Raine, C.S.3
-
2
-
-
54149084585
-
Multiple sclerosis
-
Compston A, Coles A. Multiple sclerosis. Lancet 2008 372 : 1502 1517.
-
(2008)
Lancet
, vol.372
, pp. 1502-1517
-
-
Compston, A.1
Coles, A.2
-
3
-
-
0014723429
-
The effects of experimental demyelination on conduction in the central nervous system
-
McDonald WI, Sears TA. The effects of experimental demyelination on conduction in the central nervous system. Brain 1970 93 : 583 598.
-
(1970)
Brain
, vol.93
, pp. 583-598
-
-
McDonald, W.I.1
Sears, T.A.2
-
4
-
-
33644584352
-
A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis
-
Polman CH, O'Connor PW, Havrdova E et al. A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis. N Engl J Med 2006 354 : 899 910.
-
(2006)
N Engl J Med
, vol.354
, pp. 899-910
-
-
Polman, C.H.1
O'Connor, P.W.2
Havrdova, E.3
-
5
-
-
34248647881
-
Active induction of experimental allergic encephalomyelitis
-
Stromnes IM, Goverman JM. Active induction of experimental allergic encephalomyelitis. Nat Protoc 2006 1 : 1810 1819.
-
(2006)
Nat Protoc
, vol.1
, pp. 1810-1819
-
-
Stromnes, I.M.1
Goverman, J.M.2
-
6
-
-
58149294030
-
Swift entry of myelin-specific T lymphocytes into the central nervous system in spontaneous autoimmune encephalomyelitis
-
Furtado GC, Marcondes MC, Latkowski JA, Tsai J, Wensky A, Lafaille JJ. Swift entry of myelin-specific T lymphocytes into the central nervous system in spontaneous autoimmune encephalomyelitis. J Immunol 2008 181 : 4648 4655.
-
(2008)
J Immunol
, vol.181
, pp. 4648-4655
-
-
Furtado, G.C.1
Marcondes, M.C.2
Latkowski, J.A.3
Tsai, J.4
Wensky, A.5
Lafaille, J.J.6
-
7
-
-
56149125346
-
Cutting edge: Th1 cells facilitate the entry of Th17 cells to the central nervous system during experimental autoimmune encephalomyelitis
-
O'Connor RA, Prendergast CT, Sabatos CA et al. Cutting edge: Th1 cells facilitate the entry of Th17 cells to the central nervous system during experimental autoimmune encephalomyelitis. J Immunol 2008 181 : 3750 3754.
-
(2008)
J Immunol
, vol.181
, pp. 3750-3754
-
-
O'Connor, R.A.1
Prendergast, C.T.2
Sabatos, C.A.3
-
8
-
-
0033231305
-
Assessment of animal models for MS and demyelinating disease in the design of rational therapy
-
Steinman L. Assessment of animal models for MS and demyelinating disease in the design of rational therapy. Neuron 1999 24 : 511 514.
-
(1999)
Neuron
, vol.24
, pp. 511-514
-
-
Steinman, L.1
-
9
-
-
34248650931
-
Passive induction of experimental allergic encephalomyelitis
-
Stromnes IM, Goverman JM. Passive induction of experimental allergic encephalomyelitis. Nat Protoc 2006 1 : 1952 1960.
-
(2006)
Nat Protoc
, vol.1
, pp. 1952-1960
-
-
Stromnes, I.M.1
Goverman, J.M.2
-
10
-
-
0015103005
-
Suppression of experimental allergic encephalomyelitis by a synthetic polypeptide
-
Teitelbaum D, Meshorer A, Hirshfeld T, Arnon R, Sela M. Suppression of experimental allergic encephalomyelitis by a synthetic polypeptide. Eur J Immunol 1971 1 : 242 248.
-
(1971)
Eur J Immunol
, vol.1
, pp. 242-248
-
-
Teitelbaum, D.1
Meshorer, A.2
Hirshfeld, T.3
Arnon, R.4
Sela, M.5
-
11
-
-
0026506799
-
Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin
-
Yednock TA, Cannon C, Fritz LC, Sanchez-Madrid F, Steinman L, Karin N. Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin. Nature 1992 356 : 63 6.
-
(1992)
Nature
, vol.356
, pp. 63-6
-
-
Yednock, T.A.1
Cannon, C.2
Fritz, L.C.3
Sanchez-Madrid, F.4
Steinman, L.5
Karin, N.6
-
12
-
-
0023126661
-
Exacerbations of multiple sclerosis in patients treated with gamma interferon
-
Panitch HS, Hirsch RL, Haley AS, Johnson KP. Exacerbations of multiple sclerosis in patients treated with gamma interferon. Lancet 1987 1 : 893 895.
-
(1987)
Lancet
, vol.1
, pp. 893-895
-
-
Panitch, H.S.1
Hirsch, R.L.2
Haley, A.S.3
Johnson, K.P.4
-
13
-
-
0029671318
-
Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE)
-
Ferber IA, Brocke S, Taylor-Edwards C et al. Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE). J Immunol 1996 156 : 5 7.
-
(1996)
J Immunol
, vol.156
, pp. 5-7
-
-
Ferber, I.A.1
Brocke, S.2
Taylor-Edwards, C.3
-
14
-
-
3142724732
-
Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis
-
Bettelli E, Sullivan B, Szabo SJ, Sobel RA, Glimcher LH, Kuchroo VK. Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis. J Exp Med 2004 200 : 79 87.
-
(2004)
J Exp Med
, vol.200
, pp. 79-87
-
-
Bettelli, E.1
Sullivan, B.2
Szabo, S.J.3
Sobel, R.A.4
Glimcher, L.H.5
Kuchroo, V.K.6
-
15
-
-
0037434789
-
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
-
Cua DJ, Sherlock J, Chen Y et al. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 2003 421 : 744 748.
-
(2003)
Nature
, vol.421
, pp. 744-748
-
-
Cua, D.J.1
Sherlock, J.2
Chen, Y.3
-
16
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
Langrish CL, Chen Y, Blumenschein WM et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 2005 201 : 233 240.
-
(2005)
J Exp Med
, vol.201
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
-
17
-
-
27544490377
-
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
Harrington LE, Hatton RD, Mangan PR et al. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 2005 6 : 1123 1132.
-
(2005)
Nat Immunol
, vol.6
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
-
18
-
-
33646560950
-
Transforming growth factor-beta induces development of the T(H)17 lineage
-
Mangan PR, Harrington LE, O'Quinn DB et al. Transforming growth factor-beta induces development of the T(H)17 lineage. Nature 2006 441 : 231 234.
-
(2006)
Nature
, vol.441
, pp. 231-234
-
-
Mangan, P.R.1
Harrington, L.E.2
O'Quinn, D.B.3
-
19
-
-
70449711235
-
Transforming growth factor {beta} is dispensable for the molecular orchestration of Th17 cell differentiation
-
Das J, Ren G, Zhang L et al. Transforming growth factor {beta} is dispensable for the molecular orchestration of Th17 cell differentiation. J Exp Med 2009 206 : 2407 2416.
-
(2009)
J Exp Med
, vol.206
, pp. 2407-2416
-
-
Das, J.1
Ren, G.2
Zhang, L.3
-
20
-
-
33745873727
-
A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis
-
Sutton C, Brereton C, Keogh B, Mills KH, Lavelle EC. A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis. J Exp Med 2006 203 : 1685 1691.
-
(2006)
J Exp Med
, vol.203
, pp. 1685-1691
-
-
Sutton, C.1
Brereton, C.2
Keogh, B.3
Mills, K.H.4
Lavelle, E.C.5
-
21
-
-
47549112840
-
IL-21 and TGF-beta are required for differentiation of human T(H)17 cells
-
Yang L, Anderson DE, Baecher-Allan C et al. IL-21 and TGF-beta are required for differentiation of human T(H)17 cells. Nature 2008 454 : 350 352.
-
(2008)
Nature
, vol.454
, pp. 350-352
-
-
Yang, L.1
Anderson, D.E.2
Baecher-Allan, C.3
-
22
-
-
44049104564
-
The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat
-
Manel N, Unutmaz D, Littman DR. The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat. Nat Immunol 2008 9 : 641 649.
-
(2008)
Nat Immunol
, vol.9
, pp. 641-649
-
-
Manel, N.1
Unutmaz, D.2
Littman, D.R.3
-
23
-
-
34548133583
-
Development, cytokine profile and function of human interleukin 17-producing helper T cells
-
Wilson NJ, Boniface K, Chan JR et al. Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat Immunol 2007 8 : 950 957.
-
(2007)
Nat Immunol
, vol.8
, pp. 950-957
-
-
Wilson, N.J.1
Boniface, K.2
Chan, J.R.3
-
24
-
-
60549094470
-
TGF-beta indirectly favors the development of human Th17 cells by inhibiting Th1 cells
-
Santarlasci V, Maggi L, Capone M et al. TGF-beta indirectly favors the development of human Th17 cells by inhibiting Th1 cells. Eur J Immunol 2009 39 : 207 215.
-
(2009)
Eur J Immunol
, vol.39
, pp. 207-215
-
-
Santarlasci, V.1
Maggi, L.2
Capone, M.3
-
25
-
-
30944452780
-
Therapeutic efficacy of IL-17 neutralization in murine experimental autoimmune encephalomyelitis
-
Hofstetter HH, Ibrahim SM, Koczan D et al. Therapeutic efficacy of IL-17 neutralization in murine experimental autoimmune encephalomyelitis. Cell Immunol 2005 237 : 123 130.
-
(2005)
Cell Immunol
, vol.237
, pp. 123-130
-
-
Hofstetter, H.H.1
Ibrahim, S.M.2
Koczan, D.3
-
26
-
-
33745321276
-
IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis
-
Komiyama Y, Nakae S, Matsuki T et al. IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis. J Immunol 2006 177 : 566 573.
-
(2006)
J Immunol
, vol.177
, pp. 566-573
-
-
Komiyama, Y.1
Nakae, S.2
Matsuki, T.3
-
27
-
-
61749093508
-
IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inflammation in mice
-
Haak S, Croxford AL, Kreymborg K et al. IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inflammation in mice. J Clin Invest 2009 119 : 61 9.
-
(2009)
J Clin Invest
, vol.119
, pp. 61-9
-
-
Haak, S.1
Croxford, A.L.2
Kreymborg, K.3
-
28
-
-
46749156754
-
Cutting edge: IL-21 is not essential for Th17 differentiation or experimental autoimmune encephalomyelitis
-
Coquet JM, Chakravarti S, Smyth MJ, Godfrey DI. Cutting edge: IL-21 is not essential for Th17 differentiation or experimental autoimmune encephalomyelitis. J Immunol 2008 180 : 7097 7101.
-
(2008)
J Immunol
, vol.180
, pp. 7097-7101
-
-
Coquet, J.M.1
Chakravarti, S.2
Smyth, M.J.3
Godfrey, D.I.4
-
29
-
-
40049103352
-
IL-22 is expressed by Th17 cells in an IL-23-dependent fashion, but not required for the development of autoimmune encephalomyelitis
-
Kreymborg K, Etzensperger R, Dumoutier L et al. IL-22 is expressed by Th17 cells in an IL-23-dependent fashion, but not required for the development of autoimmune encephalomyelitis. J Immunol 2007 179 : 8098 8104.
-
(2007)
J Immunol
, vol.179
, pp. 8098-8104
-
-
Kreymborg, K.1
Etzensperger, R.2
Dumoutier, L.3
-
30
-
-
68149179251
-
IL-9 as a mediator of Th17-driven inflammatory disease
-
Nowak EC, Weaver CT, Turner H et al. IL-9 as a mediator of Th17-driven inflammatory disease. J Exp Med 2009 206 : 1653 1660.
-
(2009)
J Exp Med
, vol.206
, pp. 1653-1660
-
-
Nowak, E.C.1
Weaver, C.T.2
Turner, H.3
-
31
-
-
50949091429
-
Host T cells are the main producers of IL-17 within the central nervous system during initiation of experimental autoimmune encephalomyelitis induced by adoptive transfer of Th1 cell lines
-
Lees JR, Iwakura Y, Russell JH. Host T cells are the main producers of IL-17 within the central nervous system during initiation of experimental autoimmune encephalomyelitis induced by adoptive transfer of Th1 cell lines. J Immunol 2008 180 : 8066 8072.
-
(2008)
J Immunol
, vol.180
, pp. 8066-8072
-
-
Lees, J.R.1
Iwakura, Y.2
Russell, J.H.3
-
32
-
-
46949104323
-
IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition
-
Kroenke MA, Carlson TJ, Andjelkovic AV, Segal BM. IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition. J Exp Med 2008 205 : 1535 1541.
-
(2008)
J Exp Med
, vol.205
, pp. 1535-1541
-
-
Kroenke, M.A.1
Carlson, T.J.2
Andjelkovic, A.V.3
Segal, B.M.4
-
33
-
-
40449089827
-
Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells
-
Stromnes IM, Cerretti LM, Liggitt D, Harris RA, Goverman JM. Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells. Nat Med 2008 14 : 337 342.
-
(2008)
Nat Med
, vol.14
, pp. 337-342
-
-
Stromnes, I.M.1
Cerretti, L.M.2
Liggitt, D.3
Harris, R.A.4
Goverman, J.M.5
-
34
-
-
70349735887
-
Encephalitogenic T cells that stably express both T-bet and RORgammat consistently produce IFNgamma but have a spectrum of IL-17 profiles
-
Abromson-Leeman S, Bronson RT, Dorf ME. Encephalitogenic T cells that stably express both T-bet and RORgammat consistently produce IFNgamma but have a spectrum of IL-17 profiles. J Neuroimmunol 2009 215 : 10 24.
-
(2009)
J Neuroimmunol
, vol.215
, pp. 10-24
-
-
Abromson-Leeman, S.1
Bronson, R.T.2
Dorf, M.E.3
-
35
-
-
58149190437
-
Phenotype switching by inflammation-inducing polarized Th17 cells, but not by Th1 cells
-
Shi G, Cox CA, Vistica BP, Tan C, Wawrousek EF, Gery I. Phenotype switching by inflammation-inducing polarized Th17 cells, but not by Th1 cells. J Immunol 2008 181 : 7205 7213.
-
(2008)
J Immunol
, vol.181
, pp. 7205-7213
-
-
Shi, G.1
Cox, C.A.2
Vistica, B.P.3
Tan, C.4
Wawrousek, E.F.5
Gery, I.6
-
36
-
-
67650433931
-
T-bet is essential for encephalitogenicity of both Th1 and Th17 cells
-
Yang Y, Weiner J, Liu Y et al. T-bet is essential for encephalitogenicity of both Th1 and Th17 cells. J Exp Med 2009 206 : 1549 1564.
-
(2009)
J Exp Med
, vol.206
, pp. 1549-1564
-
-
Yang, Y.1
Weiner, J.2
Liu, Y.3
-
37
-
-
33846514266
-
T-bet regulates the fate of Th1 and Th17 lymphocytes in autoimmunity
-
Gocke AR, Cravens PD, Ben LH et al. T-bet regulates the fate of Th1 and Th17 lymphocytes in autoimmunity. J Immunol 2007 178 : 1341 1348.
-
(2007)
J Immunol
, vol.178
, pp. 1341-1348
-
-
Gocke, A.R.1
Cravens, P.D.2
Ben, L.H.3
-
38
-
-
33846906914
-
IL-23 is critical in the induction but not in the effector phase of experimental autoimmune encephalomyelitis
-
Thakker P, Leach MW, Kuang W, Benoit SE, Leonard JP, Marusic S. IL-23 is critical in the induction but not in the effector phase of experimental autoimmune encephalomyelitis. J Immunol 2007 178 : 2589 2598.
-
(2007)
J Immunol
, vol.178
, pp. 2589-2598
-
-
Thakker, P.1
Leach, M.W.2
Kuang, W.3
Benoit, S.E.4
Leonard, J.P.5
Marusic, S.6
-
39
-
-
69249134656
-
IL-23-driven encephalo-tropism and Th17 polarization during CNS-inflammation in vivo
-
Gyulveszi G, Haak S, Becher B. IL-23-driven encephalo-tropism and Th17 polarization during CNS-inflammation in vivo. Eur J Immunol 2009 39 : 1864 1869.
-
(2009)
Eur J Immunol
, vol.39
, pp. 1864-1869
-
-
Gyulveszi, G.1
Haak, S.2
Becher, B.3
-
40
-
-
65249175159
-
C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE
-
Reboldi A, Coisne C, Baumjohann D et al. C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE. Nat Immunol 2009 10 : 514 523.
-
(2009)
Nat Immunol
, vol.10
, pp. 514-523
-
-
Reboldi, A.1
Coisne, C.2
Baumjohann, D.3
-
41
-
-
67349112343
-
Human Th17 cells in infection and autoimmunity
-
Sallusto F, Lanzavecchia A. Human Th17 cells in infection and autoimmunity. Microbes Infect 2009 11 : 620 624.
-
(2009)
Microbes Infect
, vol.11
, pp. 620-624
-
-
Sallusto, F.1
Lanzavecchia, A.2
-
42
-
-
0036105484
-
Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis
-
Lock C, Hermans G, Pedotti R et al. Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis. Nat Med 2002 8 : 500 508.
-
(2002)
Nat Med
, vol.8
, pp. 500-508
-
-
Lock, C.1
Hermans, G.2
Pedotti, R.3
-
43
-
-
58049087366
-
Oligoclonal myelin-reactive T-cell infiltrates derived from multiple sclerosis lesions are enriched in Th17 cells
-
Montes M, Zhang X, Berthelot L et al. Oligoclonal myelin-reactive T-cell infiltrates derived from multiple sclerosis lesions are enriched in Th17 cells. Clin Immunol 2009 130 : 133 144.
-
(2009)
Clin Immunol
, vol.130
, pp. 133-144
-
-
Montes, M.1
Zhang, X.2
Berthelot, L.3
-
44
-
-
38749143286
-
Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis
-
Tzartos JS, Friese MA, Craner MJ et al. Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis. Am J Pathol 2008 172 : 146 155.
-
(2008)
Am J Pathol
, vol.172
, pp. 146-155
-
-
Tzartos, J.S.1
Friese, M.A.2
Craner, M.J.3
-
45
-
-
0344389016
-
Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis
-
Matusevicius D, Kivisakk P, He B et al. Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis. Mult Scler 1999 5 : 101 104.
-
(1999)
Mult Scler
, vol.5
, pp. 101-104
-
-
Matusevicius, D.1
Kivisakk, P.2
He, B.3
-
46
-
-
67249090787
-
T-helper 17 cells expand in multiple sclerosis and are inhibited by interferon-beta
-
Durelli L, Conti L, Clerico M et al. T-helper 17 cells expand in multiple sclerosis and are inhibited by interferon-beta. Ann Neurol 2009 65 : 499 509.
-
(2009)
Ann Neurol
, vol.65
, pp. 499-509
-
-
Durelli, L.1
Conti, L.2
Clerico, M.3
-
47
-
-
52949094997
-
IL17 and IFNgamma production by peripheral blood mononuclear cells from clinically isolated syndrome to secondary progressive multiple sclerosis
-
Frisullo G, Nociti V, Iorio R et al. IL17 and IFNgamma production by peripheral blood mononuclear cells from clinically isolated syndrome to secondary progressive multiple sclerosis. Cytokine 2008 44 : 22 5.
-
(2008)
Cytokine
, vol.44
, pp. 22-5
-
-
Frisullo, G.1
Nociti, V.2
Iorio, R.3
-
48
-
-
34948909646
-
Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation
-
Kebir H, Kreymborg K, Ifergan I et al. Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation. Nat Med 2007 13 : 1173 1175.
-
(2007)
Nat Med
, vol.13
, pp. 1173-1175
-
-
Kebir, H.1
Kreymborg, K.2
Ifergan, I.3
-
49
-
-
70350052626
-
Preferential recruitment of interferon-gamma-expressing T(H)17 cells in multiple sclerosis
-
Kebir H, Ifergan I, Alvarez JI et al. Preferential recruitment of interferon-gamma-expressing T(H)17 cells in multiple sclerosis. Ann Neurol 2009 66 : 390 402.
-
(2009)
Ann Neurol
, vol.66
, pp. 390-402
-
-
Kebir, H.1
Ifergan, I.2
Alvarez, J.I.3
-
50
-
-
23944499790
-
A high-density screen for linkage in multiple sclerosis
-
Sawcer S, Ban M, Maranian M et al. A high-density screen for linkage in multiple sclerosis. Am J Hum Genet 2005 77 : 454 467.
-
(2005)
Am J Hum Genet
, vol.77
, pp. 454-467
-
-
Sawcer, S.1
Ban, M.2
Maranian, M.3
-
51
-
-
70149122373
-
Pathogenic CD8(+) T cells in multiple sclerosis
-
Friese MA, Fugger L. Pathogenic CD8(+) T cells in multiple sclerosis. Ann Neurol 2009 66 : 132 141.
-
(2009)
Ann Neurol
, vol.66
, pp. 132-141
-
-
Friese, M.A.1
Fugger, L.2
-
52
-
-
35848945932
-
CD8+ T cells in inflammatory demyelinating disease
-
Weiss HA, Millward JM, Owens T. CD8+ T cells in inflammatory demyelinating disease. J Neuroimmunol 2007 191 : 79 85.
-
(2007)
J Neuroimmunol
, vol.191
, pp. 79-85
-
-
Weiss, H.A.1
Millward, J.M.2
Owens, T.3
-
53
-
-
73249148836
-
Novel CD8(+) regulatory T cells suppress experimental autoimmune encephalomyelitis by TGF-beta- and IFN-gamma-dependent mechanisms
-
Chen ML, Yan BS, Kozoriz D, Weiner HL. Novel CD8(+) regulatory T cells suppress experimental autoimmune encephalomyelitis by TGF-beta- and IFN-gamma-dependent mechanisms. Eur J Immunol 2009 39 : 3423 3435.
-
(2009)
Eur J Immunol
, vol.39
, pp. 3423-3435
-
-
Chen, M.L.1
Yan, B.S.2
Kozoriz, D.3
Weiner, H.L.4
-
54
-
-
0026562142
-
Gamma delta T-cell receptor repertoire in acute multiple sclerosis lesions
-
Wucherpfennig KW, Newcombe J, Li H, Keddy C, Cuzner ML, Hafler DA. Gamma delta T-cell receptor repertoire in acute multiple sclerosis lesions. Proc Natl Acad Sci USA 1992 89 : 4588 4592.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 4588-4592
-
-
Wucherpfennig, K.W.1
Newcombe, J.2
Li, H.3
Keddy, C.4
Cuzner, M.L.5
Hafler, D.A.6
-
55
-
-
0027402498
-
Clonal expansions of activated gamma/delta T cells in recent-onset multiple sclerosis
-
Shimonkevitz R, Colburn C, Burnham JA, Murray RS, Kotzin BL. Clonal expansions of activated gamma/delta T cells in recent-onset multiple sclerosis. Proc Natl Acad Sci USA 1993 90 : 923 927.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 923-927
-
-
Shimonkevitz, R.1
Colburn, C.2
Burnham, J.A.3
Murray, R.S.4
Kotzin, B.L.5
-
56
-
-
0031043177
-
Aggravation of murine experimental allergic encephalomyelitis by administration of T-cell receptor gammadelta-specific antibody
-
Kobayashi Y, Kawai K, Ito K, Honda H, Sobue G, Yoshikai Y. Aggravation of murine experimental allergic encephalomyelitis by administration of T-cell receptor gammadelta-specific antibody. J Neuroimmunol 1997 73 : 169 174.
-
(1997)
J Neuroimmunol
, vol.73
, pp. 169-174
-
-
Kobayashi, Y.1
Kawai, K.2
Ito, K.3
Honda, H.4
Sobue, G.5
Yoshikai, Y.6
-
57
-
-
17044374687
-
Gamma delta T cells regulate the extent and duration of inflammation in the central nervous system by a Fas ligand-dependent mechanism
-
Ponomarev ED, Dittel BN. Gamma delta T cells regulate the extent and duration of inflammation in the central nervous system by a Fas ligand-dependent mechanism. J Immunol 2005 174 : 4678 4687.
-
(2005)
J Immunol
, vol.174
, pp. 4678-4687
-
-
Ponomarev, E.D.1
Dittel, B.N.2
-
58
-
-
3242747325
-
Gamma delta T cell regulation of IFN-gamma production by central nervous system-infiltrating encephalitogenic T cells: Correlation with recovery from experimental autoimmune encephalomyelitis
-
Ponomarev ED, Novikova M, Yassai M, Szczepanik M, Gorski J, Dittel BN. Gamma delta T cell regulation of IFN-gamma production by central nervous system-infiltrating encephalitogenic T cells: correlation with recovery from experimental autoimmune encephalomyelitis. J Immunol 2004 173 : 1587 1595.
-
(2004)
J Immunol
, vol.173
, pp. 1587-1595
-
-
Ponomarev, E.D.1
Novikova, M.2
Yassai, M.3
Szczepanik, M.4
Gorski, J.5
Dittel, B.N.6
-
59
-
-
0029901881
-
A pathogenic role for gamma delta T cells in relapsing-remitting experimental allergic encephalomyelitis in the SJL mouse
-
Rajan AJ, Gao YL, Raine CS, Brosnan CF. A pathogenic role for gamma delta T cells in relapsing-remitting experimental allergic encephalomyelitis in the SJL mouse. J Immunol 1996 157 : 941 949.
-
(1996)
J Immunol
, vol.157
, pp. 941-949
-
-
Rajan, A.J.1
Gao, Y.L.2
Raine, C.S.3
Brosnan, C.F.4
-
60
-
-
0032525335
-
The effect of gammadelta T cell depletion on cytokine gene expression in experimental allergic encephalomyelitis
-
Rajan AJ, Klein JD, Brosnan CF. The effect of gammadelta T cell depletion on cytokine gene expression in experimental allergic encephalomyelitis. J Immunol 1998 160 : 5955 5962.
-
(1998)
J Immunol
, vol.160
, pp. 5955-5962
-
-
Rajan, A.J.1
Klein, J.D.2
Brosnan, C.F.3
-
61
-
-
0032736525
-
Decreased severity of myelin oligodendrocyte glycoprotein peptide 33-35-induced experimental autoimmune encephalomyelitis in mice with a disrupted TCR delta chain gene
-
Spahn TW, Issazadah S, Salvin AJ, Weiner HL. Decreased severity of myelin oligodendrocyte glycoprotein peptide 33-35-induced experimental autoimmune encephalomyelitis in mice with a disrupted TCR delta chain gene. Eur J Immunol 1999 29 : 4060 4071.
-
(1999)
Eur J Immunol
, vol.29
, pp. 4060-4071
-
-
Spahn, T.W.1
Issazadah, S.2
Salvin, A.J.3
Weiner, H.L.4
-
62
-
-
2942718822
-
Gammadelta T cells enhance the expression of experimental autoimmune encephalomyelitis by promoting antigen presentation and IL-12 production
-
Odyniec A, Szczepanik M, Mycko MP, Stasiolek M, Raine CS, Selmaj KW. Gammadelta T cells enhance the expression of experimental autoimmune encephalomyelitis by promoting antigen presentation and IL-12 production. J Immunol 2004 173 : 682 694.
-
(2004)
J Immunol
, vol.173
, pp. 682-694
-
-
Odyniec, A.1
Szczepanik, M.2
Mycko, M.P.3
Stasiolek, M.4
Raine, C.S.5
Selmaj, K.W.6
-
63
-
-
0037105610
-
Gamma/delta T cell-deficient mice exhibit reduced disease severity and decreased inflammatory response in the brain in murine neurocysticercosis
-
Cardona AE, Teale JM. Gamma/delta T cell-deficient mice exhibit reduced disease severity and decreased inflammatory response in the brain in murine neurocysticercosis. J Immunol 2002 169 : 3163 3171.
-
(2002)
J Immunol
, vol.169
, pp. 3163-3171
-
-
Cardona, A.E.1
Teale, J.M.2
-
64
-
-
60749115323
-
In vivo application of mAb directed against the gammadelta TCR does not deplete but generates 'invisible' gammadelta T cells
-
Koenecke C, Chennupati V, Schmitz S, Malissen B, Forster R, Prinz I. In vivo application of mAb directed against the gammadelta TCR does not deplete but generates 'invisible' gammadelta T cells. Eur J Immunol 2009 39 : 372 379.
-
(2009)
Eur J Immunol
, vol.39
, pp. 372-379
-
-
Koenecke, C.1
Chennupati, V.2
Schmitz, S.3
Malissen, B.4
Forster, R.5
Prinz, I.6
-
65
-
-
33749138039
-
IL-17 production is dominated by gammadelta T cells rather than CD4 T cells during Mycobacterium tuberculosis infection
-
Lockhart E, Green AM, Flynn JL. IL-17 production is dominated by gammadelta T cells rather than CD4 T cells during Mycobacterium tuberculosis infection. J Immunol 2006 177 : 4662 4669.
-
(2006)
J Immunol
, vol.177
, pp. 4662-4669
-
-
Lockhart, E.1
Green, A.M.2
Flynn, J.L.3
-
66
-
-
33947677787
-
Resident Vdelta1+ gammadelta T cells control early infiltration of neutrophils after Escherichia coli infection via IL-17 production
-
Shibata K, Yamada H, Hara H, Kishihara K, Yoshikai Y. Resident Vdelta1+ gammadelta T cells control early infiltration of neutrophils after Escherichia coli infection via IL-17 production. J Immunol 2007 178 : 4466 4472.
-
(2007)
J Immunol
, vol.178
, pp. 4466-4472
-
-
Shibata, K.1
Yamada, H.2
Hara, H.3
Kishihara, K.4
Yoshikai, Y.5
-
67
-
-
68649088121
-
Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity
-
Sutton CE, Lalor SJ, Sweeney CM, Brereton CF, Lavelle EC, Mills KH. Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity. Immunity 2009 31 : 331 341.
-
(2009)
Immunity
, vol.31
, pp. 331-341
-
-
Sutton, C.E.1
Lalor, S.J.2
Sweeney, C.M.3
Brereton, C.F.4
Lavelle, E.C.5
Mills, K.H.6
-
68
-
-
2942674466
-
Foxp3: A critical regulator of the development and function of regulatory T cells
-
DOI 10.1016/j.micinf.2004.02.020, PII S1286457904001261
-
Hori S, Sakaguchi S. Foxp3: a critical regulator of the development and function of regulatory T cells. Microbes Infect 2004 6 : 745 751. (Pubitemid 38781186)
-
(2004)
Microbes and Infection
, vol.6
, Issue.8
, pp. 745-751
-
-
Hori, S.1
Sakaguchi, S.2
-
69
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 2003 4 : 330 336.
-
(2003)
Nat Immunol
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
70
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995 155 : 1151 1164.
-
(1995)
J Immunol
, vol.155
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
71
-
-
33746338535
-
Interleukin-10-secreting type 1 regulatory T cells in rodents and humans
-
Roncarolo MG, Gregori S, Battaglia M, Bacchetta R, Fleischhauer K, Levings MK. Interleukin-10-secreting type 1 regulatory T cells in rodents and humans. Immunol Rev 2006 212 : 28 50.
-
(2006)
Immunol Rev
, vol.212
, pp. 28-50
-
-
Roncarolo, M.G.1
Gregori, S.2
Battaglia, M.3
Bacchetta, R.4
Fleischhauer, K.5
Levings, M.K.6
-
72
-
-
33847651713
-
Thymic development and peripheral homeostasis of regulatory T cells
-
Liston A, Rudensky AY. Thymic development and peripheral homeostasis of regulatory T cells. Curr Opin Immunol 2007 19 : 176 185.
-
(2007)
Curr Opin Immunol
, vol.19
, pp. 176-185
-
-
Liston, A.1
Rudensky, A.Y.2
-
73
-
-
65549123867
-
Natural and adaptive foxp3+ regulatory T cells: More of the same or a division of labor?
-
Curotto de Lafaille MA, Lafaille JJ. Natural and adaptive foxp3+ regulatory T cells: more of the same or a division of labor? Immunity 2009 30 : 626 635.
-
(2009)
Immunity
, vol.30
, pp. 626-635
-
-
Curotto De Lafaille, M.A.1
Lafaille, J.J.2
-
74
-
-
33745817085
-
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
-
Liu W, Putnam AL, Xu-Yu Z et al. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J Exp Med 2006 203 : 1701 1711.
-
(2006)
J Exp Med
, vol.203
, pp. 1701-1711
-
-
Liu, W.1
Putnam, A.L.2
Xu-Yu, Z.3
-
75
-
-
42249086506
-
IL-10 suppressor activity and ex vivo Tr1 cell function are impaired in multiple sclerosis
-
Martinez-Forero I, Garcia-Munoz R, Martinez-Pasamar S et al. IL-10 suppressor activity and ex vivo Tr1 cell function are impaired in multiple sclerosis. Eur J Immunol 2008 38 : 576 586.
-
(2008)
Eur J Immunol
, vol.38
, pp. 576-586
-
-
Martinez-Forero, I.1
Garcia-Munoz, R.2
Martinez-Pasamar, S.3
-
76
-
-
33845302957
-
Alterations in CD46-mediated Tr1 regulatory T cells in patients with multiple sclerosis
-
Astier AL, Meiffren G, Freeman S, Hafler DA. Alterations in CD46-mediated Tr1 regulatory T cells in patients with multiple sclerosis. J Clin Invest 2006 116 : 3252 3257.
-
(2006)
J Clin Invest
, vol.116
, pp. 3252-3257
-
-
Astier, A.L.1
Meiffren, G.2
Freeman, S.3
Hafler, D.A.4
-
77
-
-
37149003363
-
Compromised CD4+ CD25(high) regulatory T-cell function in patients with relapsing-remitting multiple sclerosis is correlated with a reduced frequency of FOXP3-positive cells and reduced FOXP3 expression at the single-cell level
-
Venken K, Hellings N, Thewissen M et al. Compromised CD4+ CD25(high) regulatory T-cell function in patients with relapsing-remitting multiple sclerosis is correlated with a reduced frequency of FOXP3-positive cells and reduced FOXP3 expression at the single-cell level. Immunology 2008 123 : 79 89.
-
(2008)
Immunology
, vol.123
, pp. 79-89
-
-
Venken, K.1
Hellings, N.2
Thewissen, M.3
-
79
-
-
27944499757
-
Reduced suppressive effect of CD4+CD25high regulatory T cells on the T cell immune response against myelin oligodendrocyte glycoprotein in patients with multiple sclerosis
-
Haas J, Hug A, Viehover A et al. Reduced suppressive effect of CD4+CD25high regulatory T cells on the T cell immune response against myelin oligodendrocyte glycoprotein in patients with multiple sclerosis. Eur J Immunol 2005 35 : 3343 3352.
-
(2005)
Eur J Immunol
, vol.35
, pp. 3343-3352
-
-
Haas, J.1
Hug, A.2
Viehover, A.3
-
80
-
-
33744904725
-
Secondary progressive in contrast to relapsing-remitting multiple sclerosis patients show a normal CD4+CD25+ regulatory T-cell function and FOXP3 expression
-
Venken K, Hellings N, Hensen K et al. Secondary progressive in contrast to relapsing-remitting multiple sclerosis patients show a normal CD4+CD25+ regulatory T-cell function and FOXP3 expression. J Neurosci Res 2006 83 : 1432 1446.
-
(2006)
J Neurosci Res
, vol.83
, pp. 1432-1446
-
-
Venken, K.1
Hellings, N.2
Hensen, K.3
-
81
-
-
1842732224
-
Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis
-
Viglietta V, Baecher-Allan C, Weiner HL, Hafler DA. Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis. J Exp Med 2004 199 : 971 979.
-
(2004)
J Exp Med
, vol.199
, pp. 971-979
-
-
Viglietta, V.1
Baecher-Allan, C.2
Weiner, H.L.3
Hafler, D.A.4
-
82
-
-
0141481855
-
Functional assay for human CD4+CD25+ Treg cells reveals an age-dependent loss of suppressive activity
-
Tsaknaridis L, Spencer L, Culbertson N et al. Functional assay for human CD4+CD25+ Treg cells reveals an age-dependent loss of suppressive activity. J Neurosci Res 2003 74 : 296 308.
-
(2003)
J Neurosci Res
, vol.74
, pp. 296-308
-
-
Tsaknaridis, L.1
Spencer, L.2
Culbertson, N.3
-
83
-
-
23744515175
-
Decreased FOXP3 levels in multiple sclerosis patients
-
Huan J, Culbertson N, Spencer L et al. Decreased FOXP3 levels in multiple sclerosis patients. J Neurosci Res 2005 81 : 45 52.
-
(2005)
J Neurosci Res
, vol.81
, pp. 45-52
-
-
Huan, J.1
Culbertson, N.2
Spencer, L.3
-
84
-
-
66549093255
-
Regulatory T cells fail to suppress CD4(+)T-bet(+) T cells in relapsing multiple sclerosis patients
-
Frisullo G, Nociti V, Iorio R et al. Regulatory T cells fail to suppress CD4(+)T-bet(+) T cells in relapsing multiple sclerosis patients. Immunology 2008 127 : 418 428.
-
(2008)
Immunology
, vol.127
, pp. 418-428
-
-
Frisullo, G.1
Nociti, V.2
Iorio, R.3
-
85
-
-
34147092225
-
A CFSE based assay for measuring CD4+CD25+ regulatory T cell mediated suppression of auto-antigen specific and polyclonal T cell responses
-
Venken K, Thewissen M, Hellings N et al. A CFSE based assay for measuring CD4+CD25+ regulatory T cell mediated suppression of auto-antigen specific and polyclonal T cell responses. J Immunol Methods 2007 322 : 1 11.
-
(2007)
J Immunol Methods
, vol.322
, pp. 1-11
-
-
Venken, K.1
Thewissen, M.2
Hellings, N.3
-
86
-
-
33845873044
-
Interferon beta-1a therapy enhances CD4+ regulatory T-cell function: An ex vivo and in vitro longitudinal study in relapsing-remitting multiple sclerosis
-
de Andres C, Aristimuno C, de Las Heras V et al. Interferon beta-1a therapy enhances CD4+ regulatory T-cell function: an ex vivo and in vitro longitudinal study in relapsing-remitting multiple sclerosis. J Neuroimmunol 2007 182 : 204 211.
-
(2007)
J Neuroimmunol
, vol.182
, pp. 204-211
-
-
De Andres, C.1
Aristimuno, C.2
De Las Heras, V.3
-
87
-
-
33751113922
-
CD4+CD25+FoxP3+ T lymphocytes fail to suppress myelin basic protein-induced proliferation in patients with multiple sclerosis
-
Kumar M, Putzki N, Limmroth V et al. CD4+CD25+FoxP3+ T lymphocytes fail to suppress myelin basic protein-induced proliferation in patients with multiple sclerosis. J Neuroimmunol 2006 180 : 178 184.
-
(2006)
J Neuroimmunol
, vol.180
, pp. 178-184
-
-
Kumar, M.1
Putzki, N.2
Limmroth, V.3
-
88
-
-
55949119602
-
Interferon beta-induced restoration of regulatory T-cell function in multiple sclerosis is prompted by an increase in newly generated naive regulatory T cells
-
Korporal M, Haas J, Balint B et al. Interferon beta-induced restoration of regulatory T-cell function in multiple sclerosis is prompted by an increase in newly generated naive regulatory T cells. Arch Neurol 2008 65 : 1434 1439.
-
(2008)
Arch Neurol
, vol.65
, pp. 1434-1439
-
-
Korporal, M.1
Haas, J.2
Balint, B.3
-
89
-
-
18144387626
-
Induction of CD4+CD25+ regulatory T cells by copolymer-I through activation of transcription factor Foxp3
-
Hong J, Li N, Zhang X, Zheng B, Zhang JZ. Induction of CD4+CD25+ regulatory T cells by copolymer-I through activation of transcription factor Foxp3. Proc Natl Acad Sci USA 2005 102 : 6449 6454.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 6449-6454
-
-
Hong, J.1
Li, N.2
Zhang, X.3
Zheng, B.4
Zhang, J.Z.5
-
90
-
-
69949189926
-
Glucocorticoid treatment restores the impaired suppressive function of regulatory T cells in patients with relapsing-remitting multiple sclerosis
-
Xu L, Xu Z, Xu M. Glucocorticoid treatment restores the impaired suppressive function of regulatory T cells in patients with relapsing-remitting multiple sclerosis. Clin Exp Immunol 2009 158 : 26 30.
-
(2009)
Clin Exp Immunol
, vol.158
, pp. 26-30
-
-
Xu, L.1
Xu, Z.2
Xu, M.3
-
91
-
-
55849126729
-
Patients with relapsing-remitting multiple sclerosis have normal Treg function when cells expressing IL-7 receptor alpha-chain are excluded from the analysis
-
Michel L, Berthelot L, Pettre S et al. Patients with relapsing-remitting multiple sclerosis have normal Treg function when cells expressing IL-7 receptor alpha-chain are excluded from the analysis. J Clin Invest 2008 118 : 3411 3419.
-
(2008)
J Clin Invest
, vol.118
, pp. 3411-3419
-
-
Michel, L.1
Berthelot, L.2
Pettre, S.3
-
92
-
-
73349127157
-
CD39+Foxp3+ regulatory T cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis
-
Fletcher JM, Lonergan R, Costelloe L et al. CD39+Foxp3+ regulatory T cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis. J Immunol 2009 183 : 7602 7610.
-
(2009)
J Immunol
, vol.183
, pp. 7602-7610
-
-
Fletcher, J.M.1
Lonergan, R.2
Costelloe, L.3
-
93
-
-
0028102655
-
High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice
-
Lafaille JJ, Nagashima K, Katsuki M, Tonegawa S. High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice. Cell 1994 78 : 399 408.
-
(1994)
Cell
, vol.78
, pp. 399-408
-
-
Lafaille, J.J.1
Nagashima, K.2
Katsuki, M.3
Tonegawa, S.4
-
94
-
-
0032538918
-
Regulatory CD4(+) T cells expressing endogenous T cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitis
-
Olivares-Villagomez D, Wang Y, Lafaille JJ. Regulatory CD4(+) T cells expressing endogenous T cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitis. J Exp Med 1998 188 : 1883 1894.
-
(1998)
J Exp Med
, vol.188
, pp. 1883-1894
-
-
Olivares-Villagomez, D.1
Wang, Y.2
Lafaille, J.J.3
-
95
-
-
0036838536
-
Cutting edge: CD4+CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis
-
Kohm AP, Carpentier PA, Anger HA, Miller SD. Cutting edge: CD4+CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis. J Immunol 2002 169 : 4712 4716.
-
(2002)
J Immunol
, vol.169
, pp. 4712-4716
-
-
Kohm, A.P.1
Carpentier, P.A.2
Anger, H.A.3
Miller, S.D.4
-
96
-
-
1042269477
-
IL-10 is involved in the suppression of experimental autoimmune encephalomyelitis by CD25+CD4+ regulatory T cells
-
Zhang X, Koldzic DN, Izikson L et al. IL-10 is involved in the suppression of experimental autoimmune encephalomyelitis by CD25+CD4+ regulatory T cells. Int Immunol 2004 16 : 249 256.
-
(2004)
Int Immunol
, vol.16
, pp. 249-256
-
-
Zhang, X.1
Koldzic, D.N.2
Izikson, L.3
-
97
-
-
68149125252
-
Infection with a helminth parasite attenuates autoimmunity through TGF-beta-mediated suppression of Th17 and Th1 responses
-
Walsh KP, Brady MT, Finlay CM, Boon L, Mills KH. Infection with a helminth parasite attenuates autoimmunity through TGF-beta-mediated suppression of Th17 and Th1 responses. J Immunol 2009 183 : 1577 1586.
-
(2009)
J Immunol
, vol.183
, pp. 1577-1586
-
-
Walsh, K.P.1
Brady, M.T.2
Finlay, C.M.3
Boon, L.4
Mills, K.H.5
-
98
-
-
7444250675
-
Myelin proteolipid protein-specific CD4+CD25+ regulatory cells mediate genetic resistance to experimental autoimmune encephalomyelitis
-
Reddy J, Illes Z, Zhang X et al. Myelin proteolipid protein-specific CD4+CD25+ regulatory cells mediate genetic resistance to experimental autoimmune encephalomyelitis. Proc Natl Acad Sci USA 2004 101 : 15434 15439.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 15434-15439
-
-
Reddy, J.1
Illes, Z.2
Zhang, X.3
-
99
-
-
28444444122
-
CD4+CD25+ regulatory T cells limit the risk of autoimmune disease arising from T cell receptor crossreactivity
-
Stephens LA, Gray D, Anderton SM. CD4+CD25+ regulatory T cells limit the risk of autoimmune disease arising from T cell receptor crossreactivity. Proc Natl Acad Sci USA 2005 102 : 17418 17423.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 17418-17423
-
-
Stephens, L.A.1
Gray, D.2
Anderton, S.M.3
-
100
-
-
34147128572
-
Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation
-
Korn T, Reddy J, Gao W et al. Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation. Nat Med 2007 13 : 423 431.
-
(2007)
Nat Med
, vol.13
, pp. 423-431
-
-
Korn, T.1
Reddy, J.2
Gao, W.3
-
101
-
-
33646596928
-
Neuron-mediated generation of regulatory T cells from encephalitogenic T cells suppresses EAE
-
Liu Y, Teige I, Birnir B, Issazadeh-Navikas S. Neuron-mediated generation of regulatory T cells from encephalitogenic T cells suppresses EAE. Nat Med 2006 12 : 518 525.
-
(2006)
Nat Med
, vol.12
, pp. 518-525
-
-
Liu, Y.1
Teige, I.2
Birnir, B.3
Issazadeh-Navikas, S.4
-
102
-
-
23844478869
-
Natural recovery and protection from autoimmune encephalomyelitis: Contribution of CD4+CD25+ regulatory cells within the central nervous system
-
McGeachy MJ, Stephens LA, Anderton SM. Natural recovery and protection from autoimmune encephalomyelitis: contribution of CD4+CD25+ regulatory cells within the central nervous system. J Immunol 2005 175 : 3025 3032.
-
(2005)
J Immunol
, vol.175
, pp. 3025-3032
-
-
McGeachy, M.J.1
Stephens, L.A.2
Anderton, S.M.3
-
103
-
-
33645225611
-
Recovery from experimental allergic encephalomyelitis is TGF-beta dependent and associated with increases in CD4+LAP+ and CD4+CD25+ T cells
-
Zhang X, Reddy J, Ochi H, Frenkel D, Kuchroo VK, Weiner HL. Recovery from experimental allergic encephalomyelitis is TGF-beta dependent and associated with increases in CD4+LAP+ and CD4+CD25+ T cells. Int Immunol 2006 18 : 495 503.
-
(2006)
Int Immunol
, vol.18
, pp. 495-503
-
-
Zhang, X.1
Reddy, J.2
Ochi, H.3
Frenkel, D.4
Kuchroo, V.K.5
Weiner, H.L.6
-
104
-
-
34548734314
-
The inflamed central nervous system drives the activation and rapid proliferation of Foxp3+ regulatory T cells
-
O'Connor RA, Malpass KH, Anderton SM. The inflamed central nervous system drives the activation and rapid proliferation of Foxp3+ regulatory T cells. J Immunol 2007 179 : 958 966.
-
(2007)
J Immunol
, vol.179
, pp. 958-966
-
-
O'Connor, R.A.1
Malpass, K.H.2
Anderton, S.M.3
-
105
-
-
27944439639
-
Lymphocyte homeostasis following therapeutic lymphocyte depletion in multiple sclerosis
-
Cox AL, Thompson SA, Jones JL et al. Lymphocyte homeostasis following therapeutic lymphocyte depletion in multiple sclerosis. Eur J Immunol 2005 35 : 3332 3342.
-
(2005)
Eur J Immunol
, vol.35
, pp. 3332-3342
-
-
Cox, A.L.1
Thompson, S.A.2
Jones, J.L.3
-
106
-
-
54949143968
-
Alemtuzumab vs. interferon beta-1a in early multiple sclerosis
-
Coles AJ, Compston DA, Selmaj KW et al. Alemtuzumab vs. interferon beta-1a in early multiple sclerosis. N Engl J Med 2008 359 : 1786 1801.
-
(2008)
N Engl J Med
, vol.359
, pp. 1786-1801
-
-
Coles, A.J.1
Compston, D.A.2
Selmaj, K.W.3
-
107
-
-
65449122461
-
Curing CNS autoimmune disease with myelin-reactive Foxp3+ Treg
-
Stephens LA, Malpass KH, Anderton SM. Curing CNS autoimmune disease with myelin-reactive Foxp3+ Treg. Eur J Immunol 2009 39 : 1108 1117.
-
(2009)
Eur J Immunol
, vol.39
, pp. 1108-1117
-
-
Stephens, L.A.1
Malpass, K.H.2
Anderton, S.M.3
-
110
-
-
70349968220
-
IL-17 as a future therapeutic target for rheumatoid arthritis
-
van den Berg WB, Miossec P. IL-17 as a future therapeutic target for rheumatoid arthritis. Nat Rev Rheumatol 2009 5 : 549 553.
-
(2009)
Nat Rev Rheumatol
, vol.5
, pp. 549-553
-
-
Van Den Berg, W.B.1
Miossec, P.2
-
111
-
-
48849087125
-
Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: A phase II, double-blind, placebo-controlled, randomised, dose-ranging study
-
Segal BM, Constantinescu CS, Raychaudhuri A, Kim L, Fidelus-Gort R, Kasper LH. Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: a phase II, double-blind, placebo-controlled, randomised, dose-ranging study. Lancet Neurol 2008 7 : 796 804.
-
(2008)
Lancet Neurol
, vol.7
, pp. 796-804
-
-
Segal, B.M.1
Constantinescu, C.S.2
Raychaudhuri, A.3
Kim, L.4
Fidelus-Gort, R.5
Kasper, L.H.6
-
112
-
-
66449113393
-
Why did IL-12/IL-23 antibody therapy fail in multiple sclerosis?
-
Longbrake EE, Racke MK. Why did IL-12/IL-23 antibody therapy fail in multiple sclerosis? Expert Rev Neurother 2009 9 : 319 321.
-
(2009)
Expert Rev Neurother
, vol.9
, pp. 319-321
-
-
Longbrake, E.E.1
Racke, M.K.2
-
113
-
-
58149268052
-
Induction, function and regulation of IL-17-producing T cells
-
Mills KH. Induction, function and regulation of IL-17-producing T cells. Eur J Immunol 2008 38 : 2636 2649.
-
(2008)
Eur J Immunol
, vol.38
, pp. 2636-2649
-
-
Mills, K.H.1
-
114
-
-
33646433989
-
Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis
-
Chen Y, Langrish CL, McKenzie B et al. Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis. J Clin Invest 2006 116 : 1317 1326.
-
(2006)
J Clin Invest
, vol.116
, pp. 1317-1326
-
-
Chen, Y.1
Langrish, C.L.2
McKenzie, B.3
-
115
-
-
0031852288
-
IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis
-
Eugster HP, Frei K, Kopf M, Lassmann H, Fontana A. IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis. Eur J Immunol 1998 28 : 2178 2187.
-
(1998)
Eur J Immunol
, vol.28
, pp. 2178-2187
-
-
Eugster, H.P.1
Frei, K.2
Kopf, M.3
Lassmann, H.4
Fontana, A.5
-
116
-
-
57449112782
-
IL-6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3+ regulatory T cells
-
Korn T, Mitsdoerffer M, Croxford AL et al. IL-6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3+ regulatory T cells. Proc Natl Acad Sci USA 2008 105 : 18460 18465.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 18460-18465
-
-
Korn, T.1
Mitsdoerffer, M.2
Croxford, A.L.3
-
117
-
-
33846458998
-
IL-25 regulates Th17 function in autoimmune inflammation
-
Kleinschek MA, Owyang AM, Joyce-Shaikh B et al. IL-25 regulates Th17 function in autoimmune inflammation. J Exp Med 2007 204 : 161 170.
-
(2007)
J Exp Med
, vol.204
, pp. 161-170
-
-
Kleinschek, M.A.1
Owyang, A.M.2
Joyce-Shaikh, B.3
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