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Volumn 213, Issue 5, 2016, Pages 667-675

TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2; IMMUNOGLOBULIN RECEPTOR; MEMBRANE PROTEIN; TREM2 PROTEIN, MOUSE;

EID: 84969286765     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20151948     Document Type: Article
Times cited : (560)

References (30)
  • 1
    • 0037450356 scopus 로고    scopus 로고
    • PDA PP; YFP double transgenic mice: a tool to study amyloid-beta associated changes in axonal, dendritic, and synaptic structures
    • Brendza, R.P., C. O'Brien, K. Simmons, D.W. McKeel, K.R. Bales, S.M. Paul, J.W. Olney, J.R. Sanes, and D.M. Holtzman. 2003. PDA PP; YFP double transgenic mice: a tool to study amyloid-beta associated changes in axonal, dendritic, and synaptic structures. J. Comp. Neurol. 456:375-383. http://dx.doi.org/10.1002/cne.10536
    • (2003) J. Comp. Neurol. , vol.456 , pp. 375-383
    • Brendza, R.P.1    O'Brien, C.2    Simmons, K.3    McKeel, D.W.4    Bales, K.R.5    Paul, S.M.6    Olney, J.W.7    Sanes, J.R.8    Holtzman, D.M.9
  • 3
    • 84857017750 scopus 로고    scopus 로고
    • Specific lipid recognition is a general feature of CD300 and TREM molecules
    • Cannon, J.P., M. O'Driscoll, and G.W. Litman. 2012. Specific lipid recognition is a general feature of CD300 and TREM molecules. Immunogenetics. 64:39-47. http://dx.doi.org/10.1007/s00251-011-0562-4
    • (2012) Immunogenetics. , vol.64 , pp. 39-47
    • Cannon, J.P.1    O'Driscoll, M.2    Litman, G.W.3
  • 4
    • 84937113148 scopus 로고    scopus 로고
    • Microglia constitute a barrier that prevents neurotoxic protofibrillar Aß42 hotspots around plaques
    • Condello, C., P. Yuan, A. Schain, and J. Grutzendler. 2015. Microglia constitute a barrier that prevents neurotoxic protofibrillar Aß42 hotspots around plaques. Nat. Commun. 6:6176. http://dx.doi.org/10.1038/ncomms7176
    • (2015) Nat. Commun. , vol.6 , pp. 6176
    • Condello, C.1    Yuan, P.2    Schain, A.3    Grutzendler, J.4
  • 5
    • 0038784517 scopus 로고    scopus 로고
    • Pattern recognition by TREM-2: binding of anionic ligands
    • Daws, M.R., P.M. Sullam, E.C. Niemi, T.T. Chen, N.K. Tchao, and W.E. Seaman. 2003. Pattern recognition by TREM-2: binding of anionic ligands. J. Immunol. 171:594-599. http://dx.doi.org/10.4049/jimmunol.171.2.594
    • (2003) J. Immunol. , vol.171 , pp. 594-599
    • Daws, M.R.1    Sullam, P.M.2    Niemi, E.C.3    Chen, T.T.4    Tchao, N.K.5    Seaman, W.E.6
  • 8
    • 84869156976 scopus 로고    scopus 로고
    • Development and homeostasis of "resident" myeloid cells: the case of the microglia
    • Gomez Perdiguero, E., C. Schulz, and F. Geissmann. 2013. Development and homeostasis of "resident" myeloid cells: the case of the microglia. Glia. 61:112-120. http://dx.doi.org/10.1002/glia.22393
    • (2013) Glia. , vol.61 , pp. 112-120
    • Gomez Perdiguero, E.1    Schulz, C.2    Geissmann, F.3
  • 9
    • 84869161077 scopus 로고    scopus 로고
    • Regulation of microglia development and homeostasis
    • Greter, M., and M. Merad. 2013. Regulation of microglia development and homeostasis. Glia. 61:121-127. http://dx.doi.org/10.1002/glia.22408
    • (2013) Glia. , vol.61 , pp. 121-127
    • Greter, M.1    Merad, M.2
  • 10
    • 84919863377 scopus 로고    scopus 로고
    • Genetics of Alzheimer's disease
    • Guerreiro, R., and J. Hardy. 2014. Genetics of Alzheimer's disease. Neurotherapeutics. 11:732-737. http://dx.doi.org/10.1007/s13311-014-0295-9
    • (2014) Neurotherapeutics. , vol.11 , pp. 732-737
    • Guerreiro, R.1    Hardy, J.2
  • 11
    • 0034710784 scopus 로고    scopus 로고
    • Amyloid beta protein starting pyroglutamate at position 3 is a major component of the amyloid deposits in the Alzheimer's disease brain
    • Harigaya, Y., T.C. Saido, C.B. Eckman, C.M. Prada, M. Shoji, and S.G. Younkin. 2000. Amyloid beta protein starting pyroglutamate at position 3 is a major component of the amyloid deposits in the Alzheimer's disease brain. Biochem. Biophys. Res. Commun. 276:422-427. http://dx.doi.org/10.1006/bbrc.2000.3490
    • (2000) Biochem. Biophys. Res. Commun. , vol.276 , pp. 422-427
    • Harigaya, Y.1    Saido, T.C.2    Eckman, C.B.3    Prada, C.M.4    Shoji, M.5    Younkin, S.G.6
  • 13
    • 79953854897 scopus 로고    scopus 로고
    • Alzheimer's disease: the challenge of the second century
    • 77sr1
    • Holtzman, D.M., J.C. Morris, and A.M. Goate. 2011. Alzheimer's disease: the challenge of the second century. Sci. Transl. Med. 3:77sr1. http://dx.doi.org/10.1126/scitranslmed.3002369
    • (2011) Sci. Transl. Med , vol.3
    • Holtzman, D.M.1    Morris, J.C.2    Goate, A.M.3
  • 14
  • 15
    • 84920703987 scopus 로고    scopus 로고
    • Alzheimer's disease risk genes and mechanisms of disease pathogenesis
    • Karch, C.M., and A.M. Goate. 2015. Alzheimer's disease risk genes and mechanisms of disease pathogenesis. Biol. Psychiatry. 77:43-51. http://dx.doi.org/10.1016/j.biopsych.2014.05.006
    • (2015) Biol. Psychiatry. , vol.77 , pp. 43-51
    • Karch, C.M.1    Goate, A.M.2
  • 16
    • 84901399091 scopus 로고    scopus 로고
    • Truncated and modified amyloid-beta species
    • Kummer, M.P., and M.T. Heneka. 2014. Truncated and modified amyloid-beta species. Alzheimers Res. Ther. 6:28. http://dx.doi.org/10.1186/alzrt258
    • (2014) Alzheimers Res. Ther. , vol.6 , pp. 28
    • Kummer, M.P.1    Heneka, M.T.2
  • 17
    • 0029813177 scopus 로고    scopus 로고
    • Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease
    • Masliah, E., A. Sisk, M. Mallory, L. Mucke, D. Schenk, and D. Games. 1996. Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease. J. Neurosci. 16:5795-5811.
    • (1996) J. Neurosci. , vol.16 , pp. 5795-5811
    • Masliah, E.1    Sisk, A.2    Mallory, M.3    Mucke, L.4    Schenk, D.5    Games, D.6
  • 19
    • 33749521100 scopus 로고    scopus 로고
    • Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation
    • Oakley, H., S.L. Cole, S. Logan, E. Maus, P. Shao, J. Craft, A. Guillozet-Bongaarts, M. Ohno, J. Disterhoft, L. Van Eldik, et al. 2006. Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation. J. Neurosci. 26:10129-10140. http://dx.doi.org/10.1523/JNEUROSCI.1202-06.2006
    • (2006) J. Neurosci. , vol.26 , pp. 10129-10140
    • Oakley, H.1    Cole, S.L.2    Logan, S.3    Maus, E.4    Shao, P.5    Craft, J.6    Guillozet-Bongaarts, A.7    Ohno, M.8    Disterhoft, J.9    Van Eldik, L.10
  • 20
    • 67649205726 scopus 로고    scopus 로고
    • Macrophage colony-stimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and beta-catenin
    • Otero, K., I.R. Turnbull, P.L. Poliani, W. Vermi, E. Cerutti, T. Aoshi, I. Tassi, T. Takai, S.L. Stanley, M. Miller, et al. 2009. Macrophage colony-stimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and beta-catenin. Nat. Immunol. 10:734-743. http://dx.doi.org/10.1038/ni.1744
    • (2009) Nat. Immunol. , vol.10 , pp. 734-743
    • Otero, K.1    Turnbull, I.R.2    Poliani, P.L.3    Vermi, W.4    Cerutti, E.5    Aoshi, T.6    Tassi, I.7    Takai, T.8    Stanley, S.L.9    Miller, M.10
  • 22
    • 84899418705 scopus 로고    scopus 로고
    • Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease
    • Prinz, M., and J. Priller. 2014. Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease. Nat. Rev. Neurosci. 15:300-312. http://dx.doi.org/10.1038/nrn3722
    • (2014) Nat. Rev. Neurosci. , vol.15 , pp. 300-312
    • Prinz, M.1    Priller, J.2
  • 24
    • 14244268775 scopus 로고    scopus 로고
    • Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2
    • Takahashi, K., C.D. Rochford, and H. Neumann. 2005. Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2. J. Exp. Med. 201:647-657. http://dx.doi.org/10.1084/jem.20041611
    • (2005) J. Exp. Med. , vol.201 , pp. 647-657
    • Takahashi, K.1    Rochford, C.D.2    Neumann, H.3
  • 25
    • 84867608942 scopus 로고    scopus 로고
    • The genetics of Alzheimer disease
    • Tanzi, R.E. 2012. The genetics of Alzheimer disease. Cold Spring Harb. Perspect. Med. 2:10. http://dx.doi.org/10.1101/cshperspect.a006296
    • (2012) Cold Spring Harb. Perspect. Med. , vol.2 , pp. 10
    • Tanzi, R.E.1
  • 26
    • 84932645258 scopus 로고    scopus 로고
    • TREM2 and Risk of Alzheimer's Disease--Friend or Foe?
    • Tanzi, R.E. 2015. TREM2 and Risk of Alzheimer's Disease--Friend or Foe? N. Engl. J. Med. 372:2564-2565. http://dx.doi.org/10.1056/NEJMcibr1503954
    • (2015) N. Engl. J. Med. , vol.372 , pp. 2564-2565
    • Tanzi, R.E.1
  • 29
    • 84950241312 scopus 로고    scopus 로고
    • Replacement of brain-resident myeloid cells does not alter cerebral amyloid-ß deposition in mouse models of Alzheimer's disease
    • Varvel, N.H., S.A. Grathwohl, K. Degenhardt, C. Resch, A. Bosch, M. Jucker, and J.J. Neher. 2015. Replacement of brain-resident myeloid cells does not alter cerebral amyloid-ß deposition in mouse models of Alzheimer's disease. J. Exp. Med. 212:1803-1809. http://dx.doi.org/10.1084/jem.20150478
    • (2015) J. Exp. Med. , vol.212 , pp. 1803-1809
    • Varvel, N.H.1    Grathwohl, S.A.2    Degenhardt, K.3    Resch, C.4    Bosch, A.5    Jucker, M.6    Neher, J.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.