Adipocyte-specific deletion of Ip6k1 reduces diet-induced obesity by enhancing AMPK-mediated thermogenesis

Journal of Clinical Investigation

Volumn 126, Issue 11, 2016, Pages 4273-4288

  Zhu, Qingzhang ^a   Ghoshal, Sarbani ^a   Rodrigues, Ana ^a   Gao, Su ^a   Asterian, Alice ^a   Kamenecka, Theodore M ^a   Barrow, James C ^b   Chakraborty, Anutosh ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b LIEBER INSTITUTE FOR BRAIN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INOSITOL HEXAKISPHOSPHATE KINASE 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 1; IHPK1 PROTEIN, MOUSE; PPARGC1A PROTEIN, MOUSE; UCP1 PROTEIN, MOUSE;

ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE; COLD EXPOSURE; CONTROLLED STUDY; DIET INDUCED OBESITY; DOWN REGULATION; ENERGY METABOLISM; ENVIRONMENTAL TEMPERATURE; GLYCATION; IN VITRO STUDY; INGUINAL FAT; LIPID STORAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RETROPERITONEAL FAT; THERMOGENESIS; WEIGHT GAIN; WHITE ADIPOSE TISSUE; ANIMAL; CHEMICALLY INDUCED; GENETICS; KNOCKOUT MOUSE; METABOLISM; OBESITY; PATHOLOGY; SIGNAL TRANSDUCTION; WHITE ADIPOCYTE;

ADIPOCYTES, WHITE; ADIPOSE TISSUE, WHITE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ENERGY METABOLISM; MICE; MICE, KNOCKOUT; OBESITY; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR 1-ALPHA; PHOSPHOTRANSFERASES (PHOSPHATE GROUP ACCEPTOR); SIGNAL TRANSDUCTION; THERMOGENESIS; UNCOUPLING PROTEIN 1;

EID: 84994592284     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI85510     Document Type: Article

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