Deletion of inositol hexakisphosphate kinase 1 (IP6K1) reduces cell migration and invasion, conferring protection from aerodigestive tract carcinoma in mice

Cellular Signalling

Volumn 28, Issue 8, 2016, Pages 1124-1136

  Jadav, Rathan S ^a,b   Kumar, Dharmika ^a,d   Buwa, Natasha ^c   Ganguli, Shubhra ^a,b   Thampatty, Sitalakshmi R ^a,b   Balasubramanian, Nagaraj ^c   Bhandari, Rashna ^a  

^a CENTRE FOR DNA FINGERPRINTING AND DIAGNOSTICS   (India)

^b MANIPAL UNIVERSITY   (India)

^c INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH   (India)

^d NONE   (India)

Author keywords

Aerodigestive tract carcinoma; Cell invasion; Cell migration; Gene expression; Inositol hexakisphosphate kinase; Inositol pyrophosphate

Indexed keywords

FOCAL ADHESION KINASE; INOSITOL HEXAKISPHOSPHATE KINASE 1; PAXILLIN; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG; 4 NITROQUINOLINE 1 OXIDE; 4-NITROQUINOLONE-1-OXIDE; FIBRONECTIN; INOSITOL HEXAKISPHOSPHATE KINASE; INOSITOL PHOSPHATE; QUINOLONE DERIVATIVE; SMALL INTERFERING RNA;

ACTIN FILAMENT; AERODIGESTIVE TRACT CARCINOMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CARCINOGENESIS; CELL ADHESION; CELL INVASION; CELL MIGRATION; CELL MOTILITY; CELL SPREADING; CELL SURFACE; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; CONTROLLED STUDY; CYTOSKELETON REMODELING; DISEASE ASSOCIATION; DOWN REGULATION; EMBRYO; EMBRYONIC FIBROBLAST; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; FEMALE; FIBROBLAST; GASTROINTESTINAL CARCINOMA; GENE DELETION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE INACTIVATION; INTRACELLULAR SIGNALING; IP6K1 GENE; MALE; MICROARRAY ANALYSIS; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOUSE; NONHUMAN; ONCOGENIC POTENTIAL; ONCOLOGICAL PARAMETERS; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; CELL MOTION; ENZYMOLOGY; EXTRACELLULAR SPACE; GENETICS; HCT 116 CELL LINE; HEAD AND NECK TUMOR; HEK293 CELL LINE; HELA CELL LINE; HUMAN; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR INVASION;

4-NITROQUINOLINE-1-OXIDE; ANIMALS; CELL ADHESION; CELL MOVEMENT; EXTRACELLULAR SPACE; FIBROBLASTS; FIBRONECTINS; GENE DELETION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKOUT TECHNIQUES; HCT116 CELLS; HEAD AND NECK NEOPLASMS; HEK293 CELLS; HELA CELLS; HUMANS; INOSITOL PHOSPHATES; MICE, KNOCKOUT; NEOPLASM INVASIVENESS; PHOSPHOTRANSFERASES (PHOSPHATE GROUP ACCEPTOR); QUINOLONES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84969642608     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2016.04.011     Document Type: Article

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