AMPK and PFKFB3 mediate glycolysis and survival in response to mitophagy during mitotic arrest

Nature Cell Biology

Volumn 17, Issue 10, 2015, Pages 1304-1316

  Doménech, Elena ^a   Maestre, Carolina ^a   Esteban Martínez, Lorena ^b   Partida, David ^a   Pascual, Rosa ^c   Fernández Miranda, Gonzalo ^c   Seco, Esther ^b   Campos Olivas, Ramón ^a   Pérez, Manuel ^a   Megias, Diego ^a   Allen, Katherine ^d   López, Miguel ^e,f   Saha, Asish K ^d   Velasco, Guillermo ^g   Rial, Eduardo ^b   Méndez, Raúl ^c   Boya, Patricia ^b   Salazar Roa, María ^a   Malumbres, Marcos ^a  

^a Centro Nacional de Investigaciones Oncológicas   (Spain)

^b CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^c INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^d BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^f Instituto de Salud Carlos III   (Spain)

^g UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

6 PHOSPHOFRUCTO 2 KINASE FRUCTOSE 2,6 BISPHOSPHATASE 3; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MESSENGER RNA; PHOSPHOPROTEIN PHOSPHATASE; UNCLASSIFIED DRUG; 6 PHOSPHOFRUCTO 2 KINASE; ANTINEOPLASTIC AGENT; CDC20 PROTEIN, MOUSE; CELL CYCLE PROTEIN 20; PACLITAXEL; PFKFB3 PROTEIN, HUMAN; PFKFB3 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; BREAST CANCER; CANCER CELL; CANCER TISSUE; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; CYTOMETRY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FEMALE; FIBROBLAST; GLYCOLYSIS; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IN VIVO STUDY; MICROSCOPY; MICROTUBULE; MITOCHONDRION; MITOPHAGY; MITOSIS INHIBITION; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEOMICS; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; ANIMAL EMBRYO; APOPTOSIS; CELL CULTURE; CONFOCAL MICROSCOPY; CYTOLOGY; DRUG EFFECTS; DRUG SCREENING; GENETICS; KNOCKOUT MOUSE; M PHASE CELL CYCLE CHECKPOINT; MCF 7 CELL LINE; METABOLISM; NUDE MOUSE; PHYSIOLOGY; RNA INTERFERENCE; TUMOR CELL LINE; ULTRASTRUCTURE; WESTERN BLOTTING;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; BLOTTING, WESTERN; CDC20 PROTEINS; CELL LINE, TUMOR; CELL SURVIVAL; CELLS, CULTURED; EMBRYO, MAMMALIAN; FEMALE; FIBROBLASTS; GLYCOLYSIS; HUMANS; M PHASE CELL CYCLE CHECKPOINTS; MCF-7 CELLS; MICE, KNOCKOUT; MICE, NUDE; MICROSCOPY, CONFOCAL; PACLITAXEL; PHOSPHOFRUCTOKINASE-2; RNA INTERFERENCE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84942990367     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb3231     Document Type: Article

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