Inositol Pyrophosphates Mediate the DNA-PK/ATM-p53 Cell Death Pathway by Regulating CK2 Phosphorylation of Tti1/Tel2

Molecular Cell

Volumn 54, Issue 1, 2014, Pages 119-132

  Rao, Feng ^a   Cha, Jiyoung ^a   Xu, Jing ^a   Xu, Risheng ^a   Vandiver, M Scott ^a   Tyagi, Richa ^a   Tokhunts, Robert ^a   Koldobskiy, Michael A ^a   Fu, Chenglai ^a   Barrow, Roxanne ^a   Wu, Mingxuan ^b   Fiedler, Dorothea ^b   Barrow, James C ^a   Snyder, Solomon H ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 DIPHOSPHOINOSITOL PENTAKISPHOSPHATE; ATM PROTEIN; CASEIN KINASE II; CHECKPOINT KINASE 2; DNA; INOSITOL HEXAKISPHOSPHATE KINASE 2; PHOSPHATIDYLINOSITOL 3 KINASE; PHYTIC ACID; PROTEIN; PROTEIN P53; PYROPHOSPHATE; TEL2 PROTEIN; TTI1 PROTEIN; TTI2 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CANCER CELL; CELL DEATH; CONTROLLED STUDY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; RNA INTERFERENCE; SIGNAL TRANSDUCTION; UBIQUITINATION;

MURINAE;

ANIMALS; APOPTOSIS; ATAXIA TELANGIECTASIA MUTATED PROTEINS; B-LYMPHOCYTES; BINDING SITES; CARRIER PROTEINS; CASEIN KINASE II; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; ENZYME STABILITY; HCT116 CELLS; HEK293 CELLS; HUMANS; INOSITOL PHOSPHATES; MICE, KNOCKOUT; NEOPLASMS; NUCLEAR PROTEINS; PHOSPHORYLATION; PHOSPHOTRANSFERASES (PHOSPHATE GROUP ACCEPTOR); PROTO-ONCOGENE PROTEINS C-ETS; RNA INTERFERENCE; SERINE; SIGNAL TRANSDUCTION; TELOMERE-BINDING PROTEINS; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84898022580     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2014.02.020     Document Type: Article

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